id subject predicate object category relation description has_attribute source uuid:e62c6bce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e62c9f90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:4 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobupivacaine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:e62cca60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:4 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobupivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:e62cf04e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:4 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobupivacaine targets GPCR (Prostaglandin E2 receptor EP1 subtype) DrugCentral uuid:e62d1614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobupivacaine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.707']} DrugCentral uuid:e62d4012-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobupivacaine targets Ion channel (5-hydroxytryptamine receptor 3A) DrugCentral uuid:e62d67fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:4 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:e62d922e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily A member 5) DrugCentral uuid:e62dbc22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 (S)-nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e62dbc22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 (S)-nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e62ded78-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:6 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 (S)-nitrendipine is blocker of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e62e178a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:6 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e62e4188-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:6 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e62e6bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:6 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e62e967e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:6 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e62ec090-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:6 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 (S)-nitrendipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:e62ee64c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:13 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levdobutamine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:e62f0be0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:21 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e62f361a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:21 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e62f5f64-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:21 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e62f891c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48760 biolink:molecularly_interacts_with DrugCentral:21 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminopterin targets Enzyme (Folylpoly-gamma-glutamate synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:e62fb298-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:21 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminopterin is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:e62fdc46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:24 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutanoic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:e630059a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:24 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:e6302ed0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:24 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:e6305806-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:24 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:e63083a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:25 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azacitidine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e630acf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:25 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azacitidine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:e630d20e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:26 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorouracil is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:e630f6e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:26 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorouracil targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:e6311f16-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96J66 biolink:molecularly_interacts_with DrugCentral:26 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorouracil targets Transporter (ATP-binding cassette sub-family C member 11) DrugCentral uuid:e6314478-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:26 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorouracil targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e6316d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8F0 biolink:molecularly_interacts_with DrugCentral:26 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorouracil targets Enzyme (Uracil phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e6319752-ac81-11ec-8b6b-0242ac110002 UniProtKB:O26232 biolink:molecularly_interacts_with DrugCentral:27 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azaribine targets Enzyme (Orotidine 5'-phosphate decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e631c088-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03962 biolink:molecularly_interacts_with DrugCentral:27 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azaribine targets Enzyme (Orotidine 5'-phosphate decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:e631ea4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:30 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxsalen targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:e632136c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:30 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxsalen targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:e6323e64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:30 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxsalen targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e632679a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:30 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxsalen targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:e63290d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:30 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxsalen targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:e632b9fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:34 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abacavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.276']} DrugCentral uuid:e632e562-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:34 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abacavir is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:e6331118-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:34 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abacavir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e6333a44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:35 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abarelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.49']} DrugCentral uuid:e6336be0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e6336be0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e6336be0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e633bd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:e633bd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:e633bd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:e633bd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:e633bd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:e633bd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:e633bd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:e6342026-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:39 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acarbose is inhibitor of Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.697']} DrugCentral uuid:e6344952-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04746 biolink:molecularly_interacts_with DrugCentral:39 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acarbose is inhibitor of Enzyme (Pancreatic alpha-amylase) DrugCentral uuid:e6346e3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04745 biolink:molecularly_interacts_with DrugCentral:39 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acarbose targets Enzyme (Alpha-amylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e634975e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:39 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acarbose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e634c3dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:39 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acarbose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e634ee2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:39 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acarbose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e6351756-ac81-11ec-8b6b-0242ac110002 UniProtKB:P94451 biolink:molecularly_interacts_with DrugCentral:39 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acarbose targets Enzyme (Alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:e6354104-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53051 biolink:molecularly_interacts_with DrugCentral:39 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acarbose targets Enzyme (Oligo-1,6-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:e6356a08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00690 biolink:molecularly_interacts_with DrugCentral:39 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acarbose targets Enzyme (Pancreatic alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:e6359316-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:39 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acarbose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.609']} DrugCentral uuid:e635bc38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:40 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acebutolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e635e5d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:40 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acebutolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e6360ef4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:40 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acebutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e6363820-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:43 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclofenac targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e6366156-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:43 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclofenac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e6368c44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:43 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclofenac targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.227']} DrugCentral uuid:e636b566-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:43 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:e636dab4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:44 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acediasulfone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e63703b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4Z710 biolink:molecularly_interacts_with DrugCentral:44 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acediasulfone targets Unclassified (Dihydropteroate synthetase, putative) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:e6372d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0A113T0T6 biolink:molecularly_interacts_with DrugCentral:44 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acediasulfone targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:e637562e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:47 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acemetacin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:e6377c4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:47 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acemetacin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:e637a124-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:47 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acemetacin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e637cb5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:48 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acenocoumarol is inhibitor of Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e637f462-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:48 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acenocoumarol is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.114']} DrugCentral uuid:e6381d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:49 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acefylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:e6384764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:50 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceprometazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:e6386d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:e638964c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) DrugCentral uuid:e638bb36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:e638e020-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e63909ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e6393304-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:e6395c08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:e63985b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:e639aee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e639d80e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e63a0130-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:e63a2b6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20292 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Cytosolic other (Arachidonate 5-lipoxygenase-activating protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:e63a5482-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.547']} DrugCentral uuid:e63a7d90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:e63aa6c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e63ad09c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02144 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol targets Unclassified (Myoglobin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e63af9be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:52 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paracetamol is agonist of GPCR (Cannabinoid receptor 1) DrugCentral uuid:e63b1e8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:54 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetanilide targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e63b47c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9VTU8 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2, isoform A; LD26647p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:e63b7182-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9V396 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 1; GH09688p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:e63b9a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:e63bc3bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e63bece8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e63c18c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e63c41e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:e63c6c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29972 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Transporter (Aquaporin-1) DrugCentral uuid:e63c912a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e63cba56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:e63ce36e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:e63d0c72-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e63d3634-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:e63d5f42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e63d8a08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:e63db398-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:e63ddde6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:e63e06fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERQ8 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e63e3020-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e63e5938-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:e63e82c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:e63eabe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:e63ed520-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:e63efe38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e63f2818-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e63f525c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e63f7b60-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e63fa54a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29029 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Endochitinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:e63fce58-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:e63ff75c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e6402088-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e64049f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:e640731c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:e6409d24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:e640c646-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e640efe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00921 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e64144c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e641fac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e641fac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e641fac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e641fac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e6424be2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:e6424be2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:e6428080-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46510 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:e642a984-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.08']} DrugCentral uuid:e642d31e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.56']} DrugCentral uuid:e642fc18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HVB9 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:e6432544-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:e643501e-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:e64379c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75493 biolink:molecularly_interacts_with DrugCentral:56 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase-related protein 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:e643a6cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:57 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetohexamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.639']} DrugCentral uuid:e643a6cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:57 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetohexamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.639']} DrugCentral uuid:e643db56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:58 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetohydroxamic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:e6440cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:e6440cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:e6440cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:e6444564-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07374 biolink:molecularly_interacts_with DrugCentral:58 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetohydroxamic acid targets Enzyme (Urease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:e6446e40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0PXQ5 biolink:molecularly_interacts_with DrugCentral:58 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetohydroxamic acid targets Enzyme (Urease subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:e64497da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:59 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetophenazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:e644bcba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:59 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetophenazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e644e5be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:60 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racecadotril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e6450ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:60 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racecadotril is inhibitor of Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e64539d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:60 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racecadotril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:e64562c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07861 biolink:molecularly_interacts_with DrugCentral:60 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:e6458c1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08049 biolink:molecularly_interacts_with DrugCentral:60 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e645b4ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19621 biolink:molecularly_interacts_with DrugCentral:60 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:e645de10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42892 biolink:molecularly_interacts_with DrugCentral:60 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racecadotril targets Enzyme (Endothelin-converting enzyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e646070a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00800 biolink:molecularly_interacts_with DrugCentral:60 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racecadotril targets Enzyme (Thermolysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:e6463004-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:62 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetoxolone targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e6465980-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:62 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetoxolone targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:e6468248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:62 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetoxolone targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:e646ab60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:62 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e646d41e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:62 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e646fe58-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:62 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetoxolone targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e6472a04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e64752cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e6477bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:e647a696-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e647cf86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e647f84e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e6482134-ac81-11ec-8b6b-0242ac110002 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:e6484ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:e6487396-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:e648a096-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e648a096-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e648da52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:e648da52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:e6491292-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:e6491292-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:e6494b90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:e6494b90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:e64984de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e64984de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e649bd32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e649bd32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e64a01de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e64a01de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e64a01de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e64a01de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e64a01de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e64a5a3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:H6TY12 biolink:molecularly_interacts_with DrugCentral:65 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcholine targets Ion channel (Nicotinic acetylcholine receptor alpha8 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:e64a8316-ac81-11ec-8b6b-0242ac110002 UniProtKB:P99999 biolink:molecularly_interacts_with DrugCentral:66 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcysteine targets Enzyme (Cytochrome c) DrugCentral uuid:e64aa940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:66 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcysteine targets Secreted (Vascular endothelial growth factor A) DrugCentral uuid:e64ace0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04179 biolink:molecularly_interacts_with DrugCentral:66 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcysteine targets Enzyme (Superoxide dismutase [Mn], mitochondrial) DrugCentral uuid:e64af2ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48637 biolink:molecularly_interacts_with DrugCentral:66 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcysteine is modulator of Enzyme (Glutathione synthetase) DrugCentral uuid:e64b17a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:66 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylcysteine is modulator of Transporter (Cystine/glutamate transporter) DrugCentral uuid:e64b585e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e64b585e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e64b585e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e64b585e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e64b585e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e64b585e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e64b585e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e64b585e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e64bc474-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:73 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acepromazine is antagonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:e64be9ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:73 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acepromazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:e64c0ea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:73 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acepromazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e64c3774-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:74 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylsalicylic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e64c6050-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:74 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylsalicylic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e64c8a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P60045 biolink:molecularly_interacts_with DrugCentral:74 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylsalicylic acid targets Enzyme (Acidic phospholipase A2 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:e64cb348-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19440 biolink:molecularly_interacts_with DrugCentral:74 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylsalicylic acid targets Enzyme (Gamma-glutamyltranspeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:e64cdc06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:74 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e64d04c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:74 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e64d2de6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:74 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e64d5726-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:74 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylsalicylic acid is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e64d800c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:74 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylsalicylic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e64daab4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:76 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acipimox is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e64dd3a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:78 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acitretin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) DrugCentral uuid:e64df87a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:78 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acitretin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:e64e2160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:78 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acitretin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) DrugCentral uuid:e64e4712-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:78 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acitretin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:e64e723c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:80 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclarubicin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.152']} DrugCentral uuid:e64e9b36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:80 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclarubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e64ec426-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:80 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase 1) DrugCentral uuid:e64eed48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:80 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase II) DrugCentral uuid:e64eed48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:80 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase II) DrugCentral uuid:e64f2be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:e64f2be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:e64f2be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:e64f2be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:e64f2be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:e64f78e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:82 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acrivastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e64f9e5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:82 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acrivastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:e64fc81c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:82 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acrivastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e64ff0f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:85 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:e6501d9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09250 biolink:molecularly_interacts_with DrugCentral:85 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acyclovir targets Kinase (Thymidine kinase) DrugCentral uuid:e65044fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:85 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:e6507064-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:85 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:e650999a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:85 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acyclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:e650beac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09252 biolink:molecularly_interacts_with DrugCentral:85 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acyclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:e650e3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:85 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acyclovir is inhibitor of Kinase (Thymidine kinase) DrugCentral uuid:e65108a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04407 biolink:molecularly_interacts_with DrugCentral:85 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acyclovir is inhibitor of Kinase (Thymidine kinase) DrugCentral uuid:e6512e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:87 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adapalene targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e65157e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:87 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adapalene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e65180f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:87 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adapalene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:e651ab0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:87 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adapalene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e651d418-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:88 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adefovir dipivoxil is inhibitor of Polyprotein (Protein P) DrugCentral uuid:e651f970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54098 biolink:molecularly_interacts_with DrugCentral:88 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adefovir dipivoxil targets Enzyme (DNA polymerase subunit gamma-1) DrugCentral uuid:e6521e28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:88 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adefovir dipivoxil targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:e65246f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:89 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e6527bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e6527bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e6527bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e6527bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e652c738-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:e652f000-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.509']} DrugCentral uuid:e65318d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:e65342c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:e6536bb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55263 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Kinase (Adenosine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e653947e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:e653bda0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.29']} DrugCentral uuid:e653e898-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6541192-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e6543aa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9TVW2 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Kinase (Adenosine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e65463fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:e6548d52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23526 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Enzyme (Adenosylhomocysteinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.796']} DrugCentral uuid:e654ba34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e654ba34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e654ee5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BTU6 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine is inhibitor of Kinase (Phosphatidylinositol 4-kinase type 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e65517c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCG2 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine is inhibitor of Kinase (Phosphatidylinositol 4-kinase type 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e655408a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04406 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Enzyme (Glyceraldehyde-3-phosphate dehydrogenase liver) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:e6557618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e6557618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e6557618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e6557618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e655c3de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TEK3 biolink:molecularly_interacts_with DrugCentral:90 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine targets Enzyme (Histone-lysine N-methyltransferase, H3 lysine-79 specific) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e655ecba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49652 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:e6561582-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51575 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of Ion channel (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e6563f3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e656696a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e656926e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47900 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:e656bb4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e656e4c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:e6570d98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e657367e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e6575f50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41148 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets Membrane other (Endoplasmin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e6578a7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49137 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets Kinase (MAP kinase-activated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:e657b36a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:e657dc5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e6580522-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:e6582ed0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.836']} DrugCentral uuid:e65857e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12931 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets Unclassified (Heat shock protein 75 kDa, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:e65880ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29410 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets Kinase (Adenylate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:e658aa72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11142 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets Unclassified (Heat shock cognate 71 kDa protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:e658d394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMV8 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets Unclassified (Heat shock 70 kDa protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e658fc70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7TN37 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e6592632-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49653 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e659509e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJX6 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e659797a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35811 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e659a238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e659cb0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51579 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e659f922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51578 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e65a2410-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e65a4cf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:91 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine triphosphate targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e65a7640-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09467 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Enzyme (Fructose-1,6-bisphosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e65a9f80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00636 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Enzyme (Fructose-1,6-bisphosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e65ac866-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e65af174-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94759 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Ion channel (Transient receptor potential cation channel subfamily M member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:e65b1b72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e65b448a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:e65b7158-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:e65b7158-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:e65ba650-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00338 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Enzyme (L-lactate dehydrogenase A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.19']} DrugCentral uuid:e65bcff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A9J4 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Enzyme (Ketopantoate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.2']} DrugCentral uuid:e65bf8bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29410 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Kinase (Adenylate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:e65c22d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43598 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Enzyme (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:e65c4c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35820 biolink:molecularly_interacts_with DrugCentral:92 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adenosine phosphate targets Enzyme (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e65c7580-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam targets Transporter (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65ccd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:e65d6ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:94 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adiphenine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e65da7f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:e65da7f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:e65da7f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:e65da7f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:e65da7f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:e65dfe32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:99 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e65e2786-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:99 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:e65e5490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:e65e5490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:e65e907c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:e65e907c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:e65e907c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:e65ed190-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:99 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e65efa76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:99 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 agomelatine is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:e65f2370-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 agomelatine is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:e65f4c60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:100 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ajmaline is inhibitor of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e65f717c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:100 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ajmaline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e65f9b34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:100 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ajmaline is inhibitor of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:e65fc410-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:100 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ajmaline is inhibitor of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:e65fecd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:101 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alacepril is inhibitor of Enzyme (Angiotensin-converting enzyme) DrugCentral uuid:e6601618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alatrofloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:e6601618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alatrofloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:e6604a66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alatrofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:e6604a66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alatrofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:e660791e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50719 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole targets Structural (Tubulin alpha chain) DrugCentral uuid:e660a786-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:e660a786-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:e660a786-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:e660fb5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:e660fb5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:e660fb5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:e660fb5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:e660fb5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:e660fb5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:e660fb5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:e6615c94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50719 biolink:molecularly_interacts_with DrugCentral:104 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albendazole sulfoxide targets Structural (Tubulin alpha chain) DrugCentral uuid:e6618156-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salbutamol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.613']} DrugCentral uuid:e661aa3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salbutamol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:e661d386-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salbutamol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.94']} DrugCentral uuid:e661fc58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salbutamol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:e6622534-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:107 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:e66249d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:107 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alclofenac targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:e6626f62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:e6629866-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e662c124-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e662e9ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e663137c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.721']} DrugCentral uuid:e6633d98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.959']} DrugCentral uuid:e6636660-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e66396bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:e66396bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:e66396bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:e663d3a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.347']} DrugCentral uuid:e663d3a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.347']} DrugCentral uuid:e6640836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aldosterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e6643194-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aldosterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:e6645d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aldosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:e6648784-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aldosterone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.37']} DrugCentral uuid:e664b056-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alendronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:e664db08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e66503c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alendronic acid targets Enzyme (Protein farnesyltransferase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:e6652c7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e6655524-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e6657e50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alexidine targets Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e665a722-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alexidine targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:e665cfea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q932Y6 biolink:molecularly_interacts_with DrugCentral:113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alexidine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:e665f8b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WUK0 biolink:molecularly_interacts_with DrugCentral:113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alexidine is inhibitor of Enzyme (Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.97']} DrugCentral uuid:e6662256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfentanil is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:e6664b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfentanil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.951']} DrugCentral uuid:e66673e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e6669ca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e666d192-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e666d192-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e666d192-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e666d192-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e6671daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e6674686-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:e6676ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e66798fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfuzosin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:e667c21e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfuzosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:e667ebe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfuzosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:e668150c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfuzosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:e6683dca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aliskiren targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.61']} DrugCentral uuid:e668667e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aliskiren targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.678']} DrugCentral uuid:e6688fdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aliskiren is inhibitor of Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:e668b872-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9TSZ1 biolink:molecularly_interacts_with DrugCentral:119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e668e144-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6DLS0 biolink:molecularly_interacts_with DrugCentral:119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e6690a5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08424 biolink:molecularly_interacts_with DrugCentral:119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e66933ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06281 biolink:molecularly_interacts_with DrugCentral:119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aliskiren targets Enzyme (Renin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:e6695c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7M3D2 biolink:molecularly_interacts_with DrugCentral:119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e6698536-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aliskiren targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:e669add6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6DLW5 biolink:molecularly_interacts_with DrugCentral:119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:e669d888-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alizapride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:e66a0128-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alizapride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e66a29c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alizapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e66a527c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 allopurinol is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e66a7cf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00492 biolink:molecularly_interacts_with DrugCentral:124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 allopurinol targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) DrugCentral uuid:e66aa182-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 allopurinol targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e66aca36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 allopurinol targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:e66af42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9FBI2 biolink:molecularly_interacts_with DrugCentral:124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 allopurinol targets Unclassified (Shiga toxin subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:e66b1cfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:128 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e66b4650-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:128 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e66b6f2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:128 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e66b992a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alosetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e66bc40e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alosetron targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:e66becea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e66c15b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alosetron targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.218']} DrugCentral uuid:e66c3f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:130 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfacalcidol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e66c67f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:130 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfacalcidol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:e66c8c72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Transporter (Sodium- and chloride-dependent GABA transporter 1) DrugCentral uuid:e66cb8c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e66cb8c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e66cb8c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e66e12fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e66e12fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e66e12fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e66e526e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Transporter (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e66e7b22-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e66ea570-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66f0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e66ff466-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:e6701d2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem targets Unclassified (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e6704600-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpidem is partial agonist of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) DrugCentral uuid:e6706a90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.85']} DrugCentral uuid:e670938a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.457']} DrugCentral uuid:e670bd56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:e670e600-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.61']} DrugCentral uuid:e67117ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:e67117ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:e67117ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:e671630a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:e671630a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:e671630a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:e671ab1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:e671ab1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:e671ab1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:e671f234-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e671f234-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e671f234-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e67231ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:e6725af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:e67284e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprenolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.86']} DrugCentral uuid:e672ae90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e672d762-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02769 biolink:molecularly_interacts_with DrugCentral:137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprenolol targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:e6730304-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:e6732dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:e67356ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.678']} DrugCentral uuid:e673802c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprenolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.658']} DrugCentral uuid:e673a930-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e673d1da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e673fa8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e67423ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e6744c6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:e67474f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e6749e08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:e674c8a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:e674f498-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e6751fcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:e675488a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e67571f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:e6759ad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e675c3d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e675ec90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e67615bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e6763e5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e676671a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.35']} DrugCentral uuid:e67690d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e676bcb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:141 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 altretamine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:e676e564-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alvimopan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:e6770e36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alvimopan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e6773816-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alvimopan targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e67760f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alvimopan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e67789ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:e677b2d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:e677dc58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63231 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine is inhibitor of Ion channel (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e6781c86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e6781c86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e6781c86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e6781c86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e6781c86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e6781c86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e6781c86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e6788e78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q20MD5 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e678b736-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05778 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e678dff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DOF8 biolink:molecularly_interacts_with DrugCentral:144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:e67909ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ambenonium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:e6792e50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ambenonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.34']} DrugCentral uuid:e67956fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ambenonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:e6797fea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:147 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ambroxol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.744']} DrugCentral uuid:e679a934-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:147 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ambroxol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.254']} DrugCentral uuid:e679d1ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:147 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ambroxol targets Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:e679f678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:147 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ambroxol targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:e67a1f2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amcinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:e67a4d62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:e67a4d62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:e67a4d62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:e67a94b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e67a94b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e67a94b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e67ad4a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:156 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifostine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:e67afd66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:156 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifostine targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) DrugCentral uuid:e67b2200-ac81-11ec-8b6b-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:157 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amikacin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.201']} DrugCentral uuid:e67b4adc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37088 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Ion channel (Amiloride-sensitive sodium channel subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e67b73fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e67b9cd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:e67bc584-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.408']} DrugCentral uuid:e67bee38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19634 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e67c1836-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:e67c40d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16515 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride is blocker of Ion channel (Acid-sensing ion channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e67c6980-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e67c9220-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08590 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e67cbc00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:e67cec84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e67cec84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e67cec84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e67d2bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9W6Q1 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:e67d5660-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14940 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride is inhibitor of Transporter (Sodium/hydrogen exchanger 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:e67d7f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26431 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride is inhibitor of Transporter (Sodium/hydrogen exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e67da8fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50482 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e67dd1da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06869 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e67dfcb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55926 biolink:molecularly_interacts_with DrugCentral:158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:e67e2572-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:160 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoacridine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:e67e4e26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:160 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoacridine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:e67e7702-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:160 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoacridine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:e67ea038-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:161 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amineptine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e67ec946-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminocaproic acid is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e67ef1fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminocaproic acid is inhibitor of Enzyme (Tissue-type plasminogen activator) DrugCentral uuid:e67f16a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoglutethimide is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e67f3fd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoglutethimide targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:e67f689c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05108 biolink:molecularly_interacts_with DrugCentral:164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoglutethimide is inhibitor of Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) DrugCentral uuid:e67f8df4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22443 biolink:molecularly_interacts_with DrugCentral:164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoglutethimide targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:e67fb798-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoglutethimide targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:e67fe04c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:165 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminohippuric acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e6800900-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:165 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminohippuric acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e68031b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminophenazone targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:e68056bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminophenazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:e6807b4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminophenazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e680a40a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminopicoline is inhibitor of Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e680ccaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoquinuride targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e680f5fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoquinuride targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:e6811ea8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoquinuride targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e681477a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminoquinuride targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e6817056-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e6819a04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e681c39e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.112']} DrugCentral uuid:e681ec84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:e6821560-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.177']} DrugCentral uuid:e6823eb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e6826768-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e6829030-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e682b8d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e682e2b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e6830bd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e683359e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e6835f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e6838990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.912']} DrugCentral uuid:e683b244-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.647']} DrugCentral uuid:e683db2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.989']} DrugCentral uuid:e6840442-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.231']} DrugCentral uuid:e6842d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.674']} DrugCentral uuid:e68455d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.045']} DrugCentral uuid:e6847eb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:e684a82a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:e684d124-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.984']} DrugCentral uuid:e684f9d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:e68522d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.743']} DrugCentral uuid:e6854f00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.168']} DrugCentral uuid:e6857822-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.296']} DrugCentral uuid:e685a0e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.968']} DrugCentral uuid:e685ca98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.498']} DrugCentral uuid:e685f3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.701']} DrugCentral uuid:e6861ca0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.004']} DrugCentral uuid:e686455e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.207']} DrugCentral uuid:e6866f5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.176']} DrugCentral uuid:e686984c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.549']} DrugCentral uuid:e686c10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:e686e9dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.284']} DrugCentral uuid:e6871420-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.791']} DrugCentral uuid:e6873fea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:e68768e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.088']} DrugCentral uuid:e68791a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.039']} DrugCentral uuid:e687baba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37268 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e687e346-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.368']} DrugCentral uuid:e6880c18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.191']} DrugCentral uuid:e68834fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:e6885f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e68887c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.347']} DrugCentral uuid:e688b078-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e688d9fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.407']} DrugCentral uuid:e6890406-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.115']} DrugCentral uuid:e6892cce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.879']} DrugCentral uuid:e68956cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e6897ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.967']} DrugCentral uuid:e689a8c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.943']} DrugCentral uuid:e689d2fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.932']} DrugCentral uuid:e689fbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e68a253e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e68a4de8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:e68a76a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e68a9f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75151 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase PHF2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:e68aca84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29375 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e68af36a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6ZMT4 biolink:molecularly_interacts_with DrugCentral:176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:e68b1c1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.953']} DrugCentral uuid:e68b44dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.081']} DrugCentral uuid:e68b6dfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:e68b96bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.382']} DrugCentral uuid:e68bbf7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:e68be838-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.758']} DrugCentral uuid:e68c1182-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:e68c3acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:e68c638a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.625']} DrugCentral uuid:e68c8dba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e68cb696-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:e68cdf7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amisulpride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:e68d0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e68d3152-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:e68d5a88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:e68d8378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:e68dac2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:e68dd65c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e68dff2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.367']} DrugCentral uuid:e68e2814-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.456']} DrugCentral uuid:e68e50c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:e68e7b98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e68ea460-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e68ecd32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e68ef604-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:e68f1f1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e68f47da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:e68f71d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e68f9bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.686']} DrugCentral uuid:e68fc4a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:e68fed70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e6901638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e6904004-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:e69068fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.83']} DrugCentral uuid:e69091b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e690bad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e690e3e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:e6910c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e6913518-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.585']} DrugCentral uuid:e6915da4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.066']} DrugCentral uuid:e6918702-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:e691afb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e691d978-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e6920236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:e6922dba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e6925664-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e6927f18-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e692a844-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:e692d102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.771']} DrugCentral uuid:e692fa10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:e69322c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e6934c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:e6937562-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e6939e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e693c6b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e693f1c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e6941b3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e6944406-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:e6946cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e69495e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.854']} DrugCentral uuid:e694ce26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e694ce26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e694ce26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e694ce26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e694ce26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e69526dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptyline is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e6954f72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amitriptylinoxide targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e6957916-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlexanox is inhibitor of Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e695a1c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlexanox is inhibitor of Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e695cd62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlexanox targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e69601d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:e69601d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:e69601d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:e69601d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:e6964440-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.646']} DrugCentral uuid:e6966d80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.871']} DrugCentral uuid:e69696d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:e696bf9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:e696e92c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.583']} DrugCentral uuid:e697123a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.358']} DrugCentral uuid:e6973b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e69763de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e6978e36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e697b76c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:e697dc10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:e698012c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e6982b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e69853e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.507']} DrugCentral uuid:e6987cce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e698a5be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e698cee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amlodipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:e698f78a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amodiaquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e699219c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50135 biolink:molecularly_interacts_with DrugCentral:186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amodiaquine targets Enzyme (Histamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:e6994c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y251 biolink:molecularly_interacts_with DrugCentral:186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amodiaquine targets Enzyme (Heparanase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.28']} DrugCentral uuid:e699775a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amodiaquine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e699a022-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:e699c8ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:e699f1a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:e69a1ad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e69a3f82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.469']} DrugCentral uuid:e69a684a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:e69a92de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:e69abbba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.75']} DrugCentral uuid:e69ae4a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.182']} DrugCentral uuid:e69b0d7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e69b37e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e69b634e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e69b8c0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.593']} DrugCentral uuid:e69bb506-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.734']} DrugCentral uuid:e69bde78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:e69c074a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.542']} DrugCentral uuid:e69c3008-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:e69c58ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.423']} DrugCentral uuid:e69c8288-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.616']} DrugCentral uuid:e69cab50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.211']} DrugCentral uuid:e69cd3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.336']} DrugCentral uuid:e69cfcae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.365']} DrugCentral uuid:e69d26de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e69d4f9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:e69d794a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.842']} DrugCentral uuid:e69da294-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:e69dcb52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y345 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets Transporter (Sodium- and chloride-dependent glycine transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.036']} DrugCentral uuid:e69df41a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:e69e1cce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:e69e45dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e69e6eb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e69e9794-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e69ec0de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e69ef2fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e69ef2fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e69ef2fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e69f2bf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e69f54a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e69f7db2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e69fa648-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e69fe248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e69fe248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e69fe248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e69fe248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e69fe248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e69fe248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e69fe248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6a0444a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amperozide targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:e6a06cea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amperozide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:e6a0959e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:e6a0bb46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.753']} DrugCentral uuid:e6a0e422-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:e6a109a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e6a12e50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:e6a1577c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:e6a17c0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:e6a1a4ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:e6a1cd6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e6a1f66e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a22404-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:e6a24cc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a2a992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e6a3734a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e6a3734a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e6a3734a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e6a3734a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e6a3c764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:e6a3c764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:e6a3c764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:e6a40882-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:e6a43294-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ampicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e6a4599a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ampicillin targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.09']} DrugCentral uuid:e6a48258-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ampicillin targets Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:e6a4c240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6a4c240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6a4c240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6a4c240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6a4c240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6a4c240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6a4c240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6a522bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amprenavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e6a54b5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amprenavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:e6a56fe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amprenavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.172']} DrugCentral uuid:e6a598e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amprenavir targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e6a5c1ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amprenavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:e6a5ea80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amprenavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.44']} DrugCentral uuid:e6a61334-ac81-11ec-8b6b-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amprenavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:e6a63da0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amprenavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:e6a66686-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:e6a68f58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amrinone targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:e6a6b820-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:e6a6ecdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e6a6ecdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e6a6ecdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e6a6ecdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e6a738ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amsacrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e6a761d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amsacrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e6a78bce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e6a7b46e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amsacrine targets Enzyme (DNA topoisomerase I, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:e6a7dd22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:e6a806bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e6a82f70-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amsacrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e6a85bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amsacrine targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:e6a85bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amsacrine targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:e6a88fd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anagrelide is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:e6a8b8f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anagrelide targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:e6a8e1a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anastrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:e6a90b66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:213 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androisoxazole targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:e6a9300a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenediol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:e6a9595e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenediol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e6a9821c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenediol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e6a9aab2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenediol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e6a9d442-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenediol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.17']} DrugCentral uuid:e6a9fe7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenediol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:e6aa273a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenedione targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e6aa500c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenedione targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:e6aa7a00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenedione targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:e6aaa3b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37058 biolink:molecularly_interacts_with DrugCentral:215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenedione targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:e6aacc76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenedione targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e6aaf598-ac81-11ec-8b6b-0242ac110002 UniProtKB:O54939 biolink:molecularly_interacts_with DrugCentral:215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstenedione targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:e6ab1ece-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05121 biolink:molecularly_interacts_with DrugCentral:217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anecortave targets Secreted (Plasminogen activator inhibitor 1) DrugCentral uuid:e6ab434a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e6ab67d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anhydrovinblastine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:e6ab8c56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:e6abb258-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:e6abd72e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68371 biolink:molecularly_interacts_with DrugCentral:219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anhydrovinblastine targets Structural (Tubulin beta-4B chain) DrugCentral uuid:e6abfbdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anileridine is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:e6ac2076-ac81-11ec-8b6b-0242ac110002 UniProtKB:P38435 biolink:molecularly_interacts_with DrugCentral:222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anisindione is inhibitor of Enzyme (Vitamin K-dependent gamma-carboxylase) DrugCentral uuid:e6ac4574-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anisindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e6ac6e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octatropine methylbromide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:e6ac92f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octatropine methylbromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:e6acb798-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:224 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 antazoline is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:e6acdc32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:224 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 antazoline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:e6ad05ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75342 biolink:molecularly_interacts_with DrugCentral:226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dithranol targets Enzyme (Arachidonate 12-lipoxygenase, 12R-type) DrugCentral uuid:e6ad2a8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BEG3 biolink:molecularly_interacts_with DrugCentral:226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dithranol targets Enzyme (5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:e6ad534c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dithranol targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e6ad7d18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dithranol targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e6ada810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dithranol targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:e6add0ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:e6adf98c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:e6ae22d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e6ae4bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:e6ae74e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e6ae9dd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e6aec880-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e6aef224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e6af1af6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e6af43d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:e6af6d6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e6af9634-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:e6afbefc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:e6afe846-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e6b01186-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e6b03a26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:e6b06352-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:e6b08cc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:e6b0b564-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e6b0de18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:e6b106fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:e6b13142-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:e6b15a82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e6b18340-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e6b1ac8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:e6b1d5b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e6b1fe42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e6b22728-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b25b3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e6b25b3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e6b25b3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e6b25b3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b2d934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e6b3a49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e6b3a49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e6b3a49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e6b3e7fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e6b3e7fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e6b42b7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e6b42b7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e6b42b7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e6b42b7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e6b42b7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e6b489be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e6b489be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e6b489be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e6b4ca28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34949 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets Enzyme (Mannose-6-phosphate isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:e6b4f4e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e6b51dac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00987 biolink:molecularly_interacts_with DrugCentral:228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apomorphine targets Nuclear other (E3 ubiquitin-protein ligase Mdm2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:e6b54688-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apraclonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e6b57018-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apraclonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.938']} DrugCentral uuid:e6b59912-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apraclonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6b5c1da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apraclonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:e6b5f286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:e6b5f286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:e6b5f286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:e6b63296-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprepitant targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:e6b65726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprepitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:e6b68002-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29371 biolink:molecularly_interacts_with DrugCentral:230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprepitant targets GPCR (Neuromedin-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:e6b6aaa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5DUB1 biolink:molecularly_interacts_with DrugCentral:230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprepitant targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:e6b6d372-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprindine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e6b6f7e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprindine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:e6b71c88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprindine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.757']} DrugCentral uuid:e6b745e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25786 biolink:molecularly_interacts_with DrugCentral:231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprindine targets Enzyme (Proteasome subunit alpha type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:e6b76eea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32418 biolink:molecularly_interacts_with DrugCentral:231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprindine targets Transporter (Sodium/calcium exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:e6b79780-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprindine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.359']} DrugCentral uuid:e6b7c80e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:e6b7c80e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:e6b7c80e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:e6b80d1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:234 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aranidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e6b80d1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:234 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aranidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e6b83c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:237 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arbutamine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:e6b86138-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 argatroban is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:e6b88b4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 argatroban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:e6b8b408-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 argatroban targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:e6b8dcb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 argatroban targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e6b90570-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00735 biolink:molecularly_interacts_with DrugCentral:239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 argatroban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:e6b92ec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.851']} DrugCentral uuid:e6b95764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:e6b9802c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:e6b9a912-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:e6b9d266-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.131']} DrugCentral uuid:e6b9fb24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e6ba23ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e6ba4dc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:e6ba76da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:e6ba9fac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:e6bac860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:e6baf16e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e6bb1a36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:e6bb42fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:e6bb6bb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:e6bb9542-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.991']} DrugCentral uuid:e6bbbdf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:e6bbe696-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.681']} DrugCentral uuid:e6bc0f68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:e6bc38f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.169']} DrugCentral uuid:e6bc6288-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.455']} DrugCentral uuid:e6bc8b28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:e6bcb3e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:e6bcdce0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.633']} DrugCentral uuid:e6bd058a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e6bd2e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e6bd5706-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.421']} DrugCentral uuid:e6bd808c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:e6bda9cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:e6bdd3a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.202']} DrugCentral uuid:e6bdfd96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.463']} DrugCentral uuid:e6be2672-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:e6be4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:e6be77ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e6bea110-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e6becac8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:e6bef3ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:e6bf1c8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:e6bf45fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e6bf6f00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e6bf97b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e6bfc072-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e6bfead4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e6c0139c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e6c03c64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e6c0663a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:e6c08f66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:244 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arsenic trioxide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:e6c0b82e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:244 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arsenic trioxide is inhibitor of Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:e6c0dcbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.312']} DrugCentral uuid:e6c106bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.998']} DrugCentral uuid:e6c12f8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:e6c15860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:e6c18132-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:e6c1ab3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.741']} DrugCentral uuid:e6c1d420-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.025']} DrugCentral uuid:e6c1fd24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:e6c225ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.481']} DrugCentral uuid:e6c24f18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e6c277cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:e6c2a094-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.865']} DrugCentral uuid:e6c2c95c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.359']} DrugCentral uuid:e6c2f2ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.253']} DrugCentral uuid:e6c31ba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.126']} DrugCentral uuid:e6c34472-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.027']} DrugCentral uuid:e6c36d76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.819']} DrugCentral uuid:e6c39832-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:e6c3c1fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:e6c3eabc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:e6c413fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e6c43ca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:e6c4665e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e6c48fbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:e6c4b9a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:e6c4e25a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.297']} DrugCentral uuid:e6c50b18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.219']} DrugCentral uuid:e6c533d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:e6c55d7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:e6c5861a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.784']} DrugCentral uuid:e6c5aeba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.671']} DrugCentral uuid:e6c5d76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:e6c6009a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:e6c62962-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.577']} DrugCentral uuid:e6c65234-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:e6c676b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:e6c6a806-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e6c6a806-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e6c6a806-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e6c6e79e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:e6c7105c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:e6c73ae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.218']} DrugCentral uuid:e6c76386-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.065']} DrugCentral uuid:e6c78c12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.701']} DrugCentral uuid:e6c7b4ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.546']} DrugCentral uuid:e6c7ddf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.883']} DrugCentral uuid:e6c80700-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:e6c82fbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e6c85a0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:e6c882ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:e6c8ab7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:e6c8d432-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.673']} DrugCentral uuid:e6c8fda4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.868']} DrugCentral uuid:e6c9266c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.733']} DrugCentral uuid:e6c94f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:e6c977b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:e6c9a204-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:e6c9ce96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49355 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e6c9ce96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49355 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e6ca02b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75530 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Unclassified (Polycomb protein EED) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:e6ca2bfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e6ca54ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e6ca7de6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 astemizole is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.58']} DrugCentral uuid:e6caa69a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asulacrine targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:e6cacc38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.629']} DrugCentral uuid:e6caf53c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:e6cb1e54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.921']} DrugCentral uuid:e6cb46ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.921']} DrugCentral uuid:e6cb707a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.575']} DrugCentral uuid:e6cb9938-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:e6cbc1f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e6cbea8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir targets Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:e6cc13ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e6cc3cc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.27']} DrugCentral uuid:e6cc666a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:254 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atazanavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.12']} DrugCentral uuid:e6cc8f32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e6ccbab6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e6cce392-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atenolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:e6cd0c46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e6cd3586-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.93']} DrugCentral uuid:e6cd5eb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:e6cd8766-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:e6cdb024-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e6cdd9be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.69']} DrugCentral uuid:e6ce0290-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.97']} DrugCentral uuid:e6ce2b76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e6ce542a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.282']} DrugCentral uuid:e6ce7e78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:e6cea790-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e6ced076-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:e6cef9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e6cf26f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.478']} DrugCentral uuid:e6cf26f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.478']} DrugCentral uuid:e6cf5eec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:e6cf5eec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:e6cf9434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13118 biolink:molecularly_interacts_with DrugCentral:256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atomoxetine targets Nuclear other (Krueppel-like factor 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e6cfbd38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atorvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:e6cfe1be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atorvastatin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:e6d00a54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atorvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e6d033f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:e6d05e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:e6d086dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:e6d0af72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atorvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e6d0d812-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q1W675 biolink:molecularly_interacts_with DrugCentral:257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atorvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e6d10120-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e6d129c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43264 biolink:molecularly_interacts_with DrugCentral:258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atovaquone targets Enzyme (Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial) DrugCentral uuid:e6d14ed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02768 biolink:molecularly_interacts_with DrugCentral:258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atovaquone is inhibitor of Enzyme (Cytochrome b) DrugCentral uuid:e6d17358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:e6d19ce8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q54A96 biolink:molecularly_interacts_with DrugCentral:258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:e6d1c5a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atracurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:e6d1ea40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:e6d212ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atracurium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:e6d246ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:e6d246ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:e6d246ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:e6d286bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e6d2af70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e6d2d8ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e6d30164-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:e6d32a2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:e6d3538a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.907']} DrugCentral uuid:e6d37c48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:e6d3a4fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.97']} DrugCentral uuid:e6d3ce1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:e6d3f90c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:e6d423be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:e6d44c72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:e6d47526-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:e6d49e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:e6d4c6ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.59']} DrugCentral uuid:e6d4ef7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:e6d51828-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:e6d542f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:e6d56bd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:e6d59492-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e6d5bd5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:e6d5e794-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.99']} DrugCentral uuid:e6d61052-ac81-11ec-8b6b-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e6d64892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:e6d64892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:e6d64892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:e6d64892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:e6d64892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:e6d69f40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.99']} DrugCentral uuid:e6d6cfa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e6d6cfa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e6d6cfa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e6d717ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:e6d717ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:e6d717ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:e6d7585e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azapropazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:e6d77ce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azapropazone targets Enzyme (Xanthine dehydrogenase/oxidase) DrugCentral uuid:e6d7a2e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:267 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azasetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.268']} DrugCentral uuid:e6d7cbea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azatadine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:e6d7f084-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azatadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:e6d81938-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azathioprine targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:e6d83e04-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azathioprine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:e6d86294-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azathioprine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:e6d8871a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63000 biolink:molecularly_interacts_with DrugCentral:269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azathioprine targets Enzyme (Ras-related C3 botulinum toxin substrate 1) DrugCentral uuid:e6d8aba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51580 biolink:molecularly_interacts_with DrugCentral:269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azathioprine targets Enzyme (Thiopurine S-methyltransferase) DrugCentral uuid:e6d8d008-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelaic acid targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) DrugCentral uuid:e6d8f52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e6d91dba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e6d94254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e6d96b12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e6d9952e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e6d9be96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.168']} DrugCentral uuid:e6d9e754-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:e6da1062-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e6da3920-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelastine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:e6da62ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e6da8f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e6da8f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azelnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e6dabea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e6dae762-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08703 biolink:molecularly_interacts_with DrugCentral:274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:e6db1034-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70344 biolink:molecularly_interacts_with DrugCentral:274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:e6db38e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97414 biolink:molecularly_interacts_with DrugCentral:274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azimilide is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e6db650c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.39']} DrugCentral uuid:e6db8dc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azithromycin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.7']} DrugCentral uuid:e6dbb674-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azithromycin targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:e6dbdf64-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azithromycin is agonist of GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:e6dc1b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e6dc1b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e6dc1b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e6dc1b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e6dc1b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e6dc1b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e6dc7140-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.736']} DrugCentral uuid:e6dc9abc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07806 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam targets Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:e6dcc3a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.317']} DrugCentral uuid:e6dcec6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:e6dd1514-ac81-11ec-8b6b-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e6dd3f94-ac81-11ec-8b6b-0242ac110002 UniProtKB:A4ZYU9 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:e6dd6942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q83TT7 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam targets Unclassified (AmpC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e6dd91ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3S5C3 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam targets Transporter (Efflux transporter; SugE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:e6ddbb18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q48435 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:e6dde386-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:e6de0c30-ac81-11ec-8b6b-0242ac110002 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e6de4c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6de4c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6de4c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6de4c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6de4c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6de4c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6de4c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e6deadac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:281 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacitracin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.269']} DrugCentral uuid:e6ded638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:281 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacitracin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.716']} DrugCentral uuid:e6df0004-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:281 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacitracin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:e6df29da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P60932 biolink:molecularly_interacts_with DrugCentral:281 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bacitracin targets Unclassified (Undecaprenyl-diphosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:e6df5676-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets GPCR (GABA B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6df5676-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets GPCR (GABA B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6df8ec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen is agonist of GPCR (GABA-B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:e6df8ec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen is agonist of GPCR (GABA-B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:e6dfc2b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0252e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e6e0fc9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 balsalazide is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:e6e12136-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 balsalazide is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:e6e145b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 balsalazide is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:e6e16a88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 balsalazide is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:e6e18f54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bambuterol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:e6e1b3bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bambuterol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e6e1dc3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bambuterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.25']} DrugCentral uuid:e6e205e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bambuterol is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:e6e22ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bambuterol targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:e6e25736-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bamipine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:e6e27fa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:290 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 barnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e6e27fa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:290 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 barnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e6e2af38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.427']} DrugCentral uuid:e6e2d7d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:e6e3006e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:e6e32a30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e6e3533e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e6e37be8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e6e3a49c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:e6e3ce40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e6e3f6e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Y34 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate is agonist of GPCR (Probable G-protein coupled receptor 97) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:e6e41f6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04401 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate targets Unclassified (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:e6e4480c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e6e471d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:296 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belotecan is inhibitor of Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.561']} DrugCentral uuid:e6e49a50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benazepril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:e6e4c2e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benazepril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e6e4eb68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benazepril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e6e51566-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendamustine targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e6e53de8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendamustine targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:e6e566ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendamustine targets Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e6e58fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendamustine targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:e6e5b944-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendamustine targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:e6e5e1a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendamustine targets Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:e6e60a34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:e6e62ea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendroflumethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e6e658d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:e6e67d20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:e6e6a1a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bendroflumethiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:e6e6c640-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benoxaprofen is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:e6e6eb16-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benoxaprofen targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e6e7138e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.57']} DrugCentral uuid:e6e73c42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:e6e764a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:e6e78dd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e6e7b65e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.18']} DrugCentral uuid:e6e7df3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e6e807bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e6e83296-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:e6e85b18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.131']} DrugCentral uuid:e6e883cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.105']} DrugCentral uuid:e6e8ac80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:e6e8d656-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:e6e90022-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:e6e929c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e6e95342-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:e6e97bec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.486']} DrugCentral uuid:e6e9a478-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:e6e9d506-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e6e9d506-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e6e9d506-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e6ea182c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benserazide targets Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:e6ea3fe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benserazide targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e6ea68e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benserazide targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:e6ea9590-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benserazide targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:e6ea9590-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benserazide targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:e6eac95c-ac81-11ec-8b6b-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benserazide targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:e6eaf1f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03313 biolink:molecularly_interacts_with DrugCentral:314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benserazide targets Unclassified (Genome polyprotein [Cleaved into: P1; Capsid protein VP0) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e6eb1a60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52789 biolink:molecularly_interacts_with DrugCentral:314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benserazide targets Kinase (Hexokinase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:e6eb4396-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:317 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzarone targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:e6eb6c18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:317 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e6eb94ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:e6ebbdee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:e6ebe88c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:e6ec1154-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:e6ec3a26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:e6ec6398-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:e6ec8c2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.976']} DrugCentral uuid:e6ecb4ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.908']} DrugCentral uuid:e6ecde72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.711']} DrugCentral uuid:e6ed076c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:e6ed3016-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e6ed58ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.32']} DrugCentral uuid:e6ed814c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:e6edab68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:e6edd430-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzbromarone is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e6ee0bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15392 biolink:molecularly_interacts_with DrugCentral:321 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benziodarone targets Unclassified (Baculoviral IAP repeat-containing protein 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e6ee3542-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:321 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benziodarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e6ee5dd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:e6ee825e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:e6eea6da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:e6eecd04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:e6eef176-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:e6ef15fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:e6ef3b04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UI33 biolink:molecularly_interacts_with DrugCentral:323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 11 subunit alpha) DrugCentral uuid:e6ef5f8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:e6ef871c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01118 biolink:molecularly_interacts_with DrugCentral:323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 7 subunit alpha) DrugCentral uuid:e6efae68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['3.495']} DrugCentral uuid:e6efd7d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzonatate targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e6effc24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzphetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:e6f02140-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzphetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:e6f04594-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzphetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e6f069fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzphetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:e6f08e5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzquinamide is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:e6f0b75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzquinamide is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e6f0dff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzquinamide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.445']} DrugCentral uuid:e6f1088a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzquinamide targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.241']} DrugCentral uuid:e6f13206-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzquinamide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.865']} DrugCentral uuid:e6f15f56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzquinamide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:e6f187ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzquinamide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:e6f1b06e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:e6f1d4fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzthiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.17']} DrugCentral uuid:e6f1fe20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:e6f22292-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:e6f24740-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzthiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:e6f26bee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:e6f294de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:e6f2bd92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:e6f2e61e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:e6f30f36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.157']} DrugCentral uuid:e6f3398e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:e6f36242-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:e6f38ad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.888']} DrugCentral uuid:e6f3b404-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:e6f3dc86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.654']} DrugCentral uuid:e6f40558-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:e6f42de4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.926']} DrugCentral uuid:e6f456d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.636']} DrugCentral uuid:e6f48096-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:e6f4a922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:e6f4d1ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:e6f4fcec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:e6f52578-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:e6f54f08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.253']} DrugCentral uuid:e6f5780c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:e6f5a106-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:e6f5c9a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:e6f5f246-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e6f61ab4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:e6f648ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:e6f671bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:e6f69a5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e6f6c432-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q695T7 biolink:molecularly_interacts_with DrugCentral:333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzatropine is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:e6f6ecf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:335 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzyl benzoate targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:e6f71572-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:335 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzyl benzoate targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e6f73dfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepotastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:e6f762b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e6f7870a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:e6f7afa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:e6f7d85e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.149']} DrugCentral uuid:e6f801bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:e6f82a66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e6f85306-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:e6f87b92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:e6f8ae14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:e6f8ae14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:e6f8ae14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:e6f8ed20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil is gating inhibitor of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e6f91692-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:e6f93b86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:e6f9600c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beraprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:e6f98898-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beraprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e6f9b142-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e6f9da82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:e6fa03c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:e6fa2c3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2Q167 biolink:molecularly_interacts_with DrugCentral:345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betacarotene targets Unclassified (Core protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:e6fa55f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betahistine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:e6fa81a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betahistine is inverse agonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:e6faaa7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:e6fad342-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone targets Cytosolic other (Annexin A1) DrugCentral uuid:e6faf7be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:349 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:e6fb1cb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone benzoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:e6fb4142-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:e6fb6640-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone dipropionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:e6fb8ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:354 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone valerate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:e6fbb3ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamipron targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:e6fbdc56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamipron targets Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:e6fc0528-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betaxolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:e6fc2e40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e6fc57c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.98']} DrugCentral uuid:e6fc8052-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:e6fca8e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betaxolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.53']} DrugCentral uuid:e6fcd1a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betaxolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.76']} DrugCentral uuid:e6fcfaf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:357 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betazole is agonist of GPCR (Histamine H2 receptor) DrugCentral uuid:e6fd1f76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:e6fd49ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:e6fd7304-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:e6fd9bea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:e6fdc494-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bethanechol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:e6fded52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VH27 biolink:molecularly_interacts_with DrugCentral:358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bethanechol targets GPCR (Muscarinic receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e6fe1746-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betanidine is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:e6fe3ec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:360 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bevantolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:e6fe661a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:e6fe8f0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene is antagonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e6feb804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e6fee0c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:e6ff0994-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:e6ff3234-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e6ff5b92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e6ff8446-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:e6ffad54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:e6ffd626-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e70000e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05343 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e700296e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43174 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Enzyme (Cytochrome P450 26A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:e700533a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NR63 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Enzyme (Cytochrome P450 26B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:e7007bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:e700a60a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13133 biolink:molecularly_interacts_with DrugCentral:361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bexarotene targets Nuclear other (Oxysterols receptor LXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:e700ce82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bezafibrate targets Enzyme (Lipoprotein lipase) DrugCentral uuid:e700f2f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bezafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e7011c2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bezafibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.178']} DrugCentral uuid:e70145ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bezafibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:e7016e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bezafibrate targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.48']} DrugCentral uuid:e70196f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bezafibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:e701c09e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bezafibrate is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) DrugCentral uuid:e701e4e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:e7020946-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:e7022dc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biapenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:e7025270-ac81-11ec-8b6b-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:e70276f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biapenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:e7029b90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:367 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bicalutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:e702c444-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:367 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bicalutamide targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e702ecc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:367 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bicalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e7031624-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:367 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bicalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:e7033ec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:367 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bicalutamide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:e7036778-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63449 biolink:molecularly_interacts_with DrugCentral:367 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bicalutamide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e703916c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bifemelane targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:e703bcd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bifonazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e703e554-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bifonazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e7040e9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bifonazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:e70437a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bifonazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:e704609c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bimatoprost targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e704895a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bimatoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e704b218-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biotin targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e704dbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.32']} DrugCentral uuid:e7050524-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e7052de2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:e7055740-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.62']} DrugCentral uuid:e7058314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biperiden targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.201']} DrugCentral uuid:e705adbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biperiden targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:e705d242-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bisacodyl targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:e705fad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bisacodyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.011']} DrugCentral uuid:e7062512-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bisacodyl targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e7064db2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15559 biolink:molecularly_interacts_with DrugCentral:376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bisantrene targets Enzyme (NAD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e706765c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bisoprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:e7069fc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bisoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:e706c878-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bisoprolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e706f118-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bisoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:e70719cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bisoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:e70743de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bisulepine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:e70768fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bitolterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:e7078d6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bivalirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:e707b60c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 blonanserin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:e707df24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 blonanserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e70807f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 blonanserin is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.854']} DrugCentral uuid:e70830be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 blonanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.092']} DrugCentral uuid:e7085968-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:e7088258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.345']} DrugCentral uuid:e708ab48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.014']} DrugCentral uuid:e708d3de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bopindolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.463']} DrugCentral uuid:e708fc92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bopindolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.262']} DrugCentral uuid:e70927b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:e709503e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bopindolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:e70979ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bopindolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.65']} DrugCentral uuid:e709a296-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:e709cbea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e709f494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e70a1d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e70a4642-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:e70a6ee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e70a97a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e70ac0a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:e70ae9ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e70b1284-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.745']} DrugCentral uuid:e70b3b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99460 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Cytosolic other (26S proteasome non-ATPase regulatory subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:e70b63e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25786 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit alpha type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.208']} DrugCentral uuid:e70b8dc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e70bb644-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:e70bdeda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:e70c07ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08311 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Cathepsin G) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e70c31c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:e70c5a68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e70c82fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17538 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Chymotrypsinogen B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:e70cabf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28062 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e70cd5a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e70cfe32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:e70d2704-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:e70d5058-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e70d7916-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:e70da2d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:e70dcb8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e70df468-ac81-11ec-8b6b-0242ac110002 UniProtKB:A5PKW4 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Unclassified (PH and SEC7 domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:e70e24ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:e70e24ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:e70e24ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:e70e6448-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00766 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Alpha-chymotrypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e70e8e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IJT1 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:e70eb9e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28063 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.78']} DrugCentral uuid:e70ee31e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28065 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e70f0ba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40306 biolink:molecularly_interacts_with DrugCentral:391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:e70f34ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosentan targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:e70f5948-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosentan targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:e70f81f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:e70faad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e70fd3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosentan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:e70ffc86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q29010 biolink:molecularly_interacts_with DrugCentral:392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosentan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:e710256c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosentan targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:e7104dda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21451 biolink:molecularly_interacts_with DrugCentral:392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosentan targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e710790e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bretylium targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:e7109d62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bretylium targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:e710c1fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bretylium is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:e710e6aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.387']} DrugCentral uuid:e7110ffe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:e7113920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:e71161c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:e7118b3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:e711b4c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.073']} DrugCentral uuid:e711dd9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e7120774-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e7123000-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:e712599a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:e71289ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e71289ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e71289ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e712d1e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:e712d1e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:e712d1e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:e7131132-ac81-11ec-8b6b-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brimonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:e71339e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:e7136290-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e7138bb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e713b484-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:e713dd2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e714065a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e7142ffe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e71458a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e714813e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e714aa9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e714d35a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:e714fc2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e71524cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:e7154f42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e71577f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e715a08c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:e715c92c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e715f384-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e7161c38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:e71644c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:e7166d64-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:e716971c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:e716bfc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:e716e8d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:e7171174-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e7173aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e7176340-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e7178be0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:e717b69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brinzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:e717df3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:e71807f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brivudine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e718307c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06479 biolink:molecularly_interacts_with DrugCentral:397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e71859a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e718820c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:398 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brodimoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:e718aa98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:398 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:e718d3a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:398 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e718fc78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:398 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:e7192518-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:398 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:e7194ea8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:398 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:e7197752-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:398 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:e719a18c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:398 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:e719d1fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e719d1fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e719d1fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e71a0a5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromfenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e71a3390-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromfenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:e71a6004-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromfenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e71a6004-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromfenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e71a948e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromhexine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:e71abdb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromhexine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:e71ae65a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromhexine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.708']} DrugCentral uuid:e71b0f04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromhexine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:e71b37ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.858']} DrugCentral uuid:e71b617a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:e71b8a1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e71bb2ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:e71bdb5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e71c04e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e71c2d80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:e71c56a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e71c7f6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e71ca86e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e71cd104-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e71cf990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:e71d2334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e71d4f26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e71d77ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e71da11a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e71dca46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e71df2f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e71e1b90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e71e443a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e71e6d52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.86']} DrugCentral uuid:e71e9606-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:e71ebea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.708']} DrugCentral uuid:e71ee75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:e71f10a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:e71f391c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e71f6194-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:e71f8a20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e71fb40a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7TSF2 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets Transporter (Vesicular glutamate transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:e71fdca0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e7200d06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:e7200d06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:e7200d06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:e7205c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e7205c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e7205c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e7205c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e7205c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e720b742-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:e720b742-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromocriptine targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:e720ebe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:404 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:e7211476-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e7213d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromopride targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:e72165fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e7218f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:e721b82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:e721e0ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e722094e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e7223266-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:e7225b06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.119']} DrugCentral uuid:e72283a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.745']} DrugCentral uuid:e722ae58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:e722d72a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e722ffc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.319']} DrugCentral uuid:e7232892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bromperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e72351fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brompheniramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e7237a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brompheniramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.218']} DrugCentral uuid:e723ab82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e723ab82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e723ab82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e723eb9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:409 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brotizolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e724140a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 broxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:e7243d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buclizine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:e72461e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e7248750-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:e724afc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:e724d85e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide targets Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.5']} DrugCentral uuid:e72500ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e7252aac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e7255342-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.701']} DrugCentral uuid:e7257c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.963']} DrugCentral uuid:e725a4a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:e725cd9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e725f626-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04401 biolink:molecularly_interacts_with DrugCentral:419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budesonide targets Unclassified (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:e7261ed0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:e726603e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:e726603e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:e726603e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:e726603e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:e726603e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:e726603e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:e726603e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:e726cd6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buflomedil targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:e726f274-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buflomedil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7271b64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buflomedil targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e7274404-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buflomedil targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e7276902-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buflomedil targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:e7278dba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buflomedil targets GPCR (Alpha-1D adrenergic receptor) DrugCentral uuid:e727b358-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buflomedil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:e727d8e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buflomedil targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:e727fd5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buflomedil targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e72825ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufuralol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e7285150-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufuralol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:e72879dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufuralol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e7289e62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufuralol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ks', 'has_quantitative_value': ['4.59']} DrugCentral uuid:e728c7b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bumetanide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e728f06a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bumetanide targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e729191e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bumetanide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e72941b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bumetanide is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e7296aae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bunazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e7298f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bunazosin targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:e729b39c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bunazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:e729d818-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bunazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) DrugCentral uuid:e729fc9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobunolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.399']} DrugCentral uuid:e72a2642-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobunolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.263']} DrugCentral uuid:e72a4ece-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobunolol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:e72a776e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobunolol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.585']} DrugCentral uuid:e72aa13a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobunolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:e72ac9f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.593']} DrugCentral uuid:e72af298-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobunolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e72b1b6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e72b4464-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e72b6cfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:e72b9572-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:e72bbe58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.293']} DrugCentral uuid:e72be874-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e72c1100-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.514']} DrugCentral uuid:e72c3978-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:e72c6204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.233']} DrugCentral uuid:e72c8b12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:e72cb3b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e72cdc7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e72d04fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z0V1 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:e72d2e3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e72d56c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupranolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e72d7f7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupranolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e72daa60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e72dd530-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buprenorphine is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.29']} DrugCentral uuid:e72dfdf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buprenorphine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e72e26fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buprenorphine is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:e72e5014-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buprenorphine is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:e72e78be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buprenorphine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:e72ea190-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buprenorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.89']} DrugCentral uuid:e72eca44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buprenorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:e72ef398-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buprenorphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:e72f1c88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buprenorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e72f4528-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e72f6db4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e72f979e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.796']} DrugCentral uuid:e72fc4b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:e72fee6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:e73012dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e7303bd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e7306476-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.846']} DrugCentral uuid:e7308d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:e730ba66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:e730ba66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:e730f242-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e730f242-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e7312622-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buserelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.569']} DrugCentral uuid:e7314eb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.52']} DrugCentral uuid:e73179c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01776 biolink:molecularly_interacts_with DrugCentral:436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:e731a2c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:e731cc26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:e73205c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e7322efa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:e73257a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e732801c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:e732a952-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:e732d1fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:e732fa74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.435']} DrugCentral uuid:e7332300-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:e7334e84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e7337738-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.277']} DrugCentral uuid:e733a10e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:e733cb0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.471']} DrugCentral uuid:e733f3ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:e7341c74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e734451e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:e7346e68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:e734971c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e734bfd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e734e898-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e735134a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e7353be0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e735643a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e7358cc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e735b5ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:e735de92-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:e7360714-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e7362faa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:e736647a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e736647a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e736647a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e736647a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e736b736-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e736b736-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e736b736-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e7370768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:e7370768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:e7370768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:e7370768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:e7370768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:e7376636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:e7376636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:e7376636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:e737adda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:e737adda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:e737adda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:e737ed4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:438 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 busulfan targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.283']} DrugCentral uuid:e7381e78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e7381e78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e7381e78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e738600e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e738600e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e738600e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e7389862-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butenafine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:e738c350-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butenafine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.779']} DrugCentral uuid:e738ec9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butenafine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.125']} DrugCentral uuid:e7391562-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butenafine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:e7393dda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butenafine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:e73966de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butenafine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.161']} DrugCentral uuid:e739901e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butenafine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:e739b49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butenafine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.805']} DrugCentral uuid:e739ddc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butenafine targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:e73a063e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92206 biolink:molecularly_interacts_with DrugCentral:444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butenafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.347']} DrugCentral uuid:e73a2fce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:450 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butoconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:e73a545e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:454 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butorphanol is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:e73a7e34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:454 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butorphanol is partial agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:e73aa788-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:454 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butorphanol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e73ad01e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:455 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butriptyline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:e73af8b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:455 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butriptyline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:e73b21a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:455 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.405']} DrugCentral uuid:e73b4a26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:458 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:e73b6e8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:458 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:e73b92e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:458 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:e73bb7ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:458 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:e73bdc7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e73c0542-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:e73c2e00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:e73c57ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e73c82f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e73cabd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:e73cd4e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e73cfde4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e73d26b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e73d4f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e73d7800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e73da186-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e73dca3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e73df3f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e73e1c92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e73e46ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:e73e6f8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabergoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e73e9820-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:461 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cadralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:e73ebca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:461 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cadralazine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:e73ee5b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:e73f0e54-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:e73f36fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:e73f6084-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e73f89a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:e73fb250-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e73fdac8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:e74004f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00489 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets Enzyme (Glycogen phosphorylase, muscle form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:e7402e42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e74056d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e7407f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:e740a87c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:e740d5a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:e740d5a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:e7411596-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e7411596-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e7411596-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e7411596-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e74160e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2T3 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets Enzyme (Guanine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:e7418972-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:e741b230-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60614 biolink:molecularly_interacts_with DrugCentral:463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e741dbde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:464 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcifediol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:e742014a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:465 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcipotriene is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.51']} DrugCentral uuid:e74229e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitriol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:e7424e70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitriol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e7427742-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitriol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:e7429baa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02774 biolink:molecularly_interacts_with DrugCentral:466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitriol targets Secreted (Vitamin D-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:e742c44a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:e742ecf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42392 biolink:molecularly_interacts_with DrugCentral:466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.6']} DrugCentral uuid:e74316c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28037 biolink:molecularly_interacts_with DrugCentral:466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:e7433f2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:A3RGC1 biolink:molecularly_interacts_with DrugCentral:466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitriol targets Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.15']} DrugCentral uuid:e7436918-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9PTN2 biolink:molecularly_interacts_with DrugCentral:466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitriol targets Nuclear hormone receptor (Vitamin D3 receptor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:e74391b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camphor targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e743bd14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camphor is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:e743e8b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:471 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camostat targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:e7441188-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:471 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camostat is inhibitor of Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e7443a32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06870 biolink:molecularly_interacts_with DrugCentral:471 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camostat targets Enzyme (Kallikrein-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:e7446368-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01177 biolink:molecularly_interacts_with DrugCentral:471 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camostat targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:e7448c3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:471 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camostat targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:e744b4da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:471 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camostat targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e744de38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:471 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camostat targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:e7450700-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:471 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camostat targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:e7452f82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04756 biolink:molecularly_interacts_with DrugCentral:471 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camostat targets Enzyme (Hepatocyte growth factor activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e7455886-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15393 biolink:molecularly_interacts_with DrugCentral:471 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camostat is inhibitor of Enzyme (Transmembrane protease serine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e7458298-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:472 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 camylofin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e745ab60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:e745d3e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:e745fc6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:e746261c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34976 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:e7464ef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBT6 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase kappa) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:e746777a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNA4 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase iota) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e746a024-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y253 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase eta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:e746c964-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e746f1f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e7471a90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:e74743a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e7476d56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:e747960a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e747bee6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:e747e7e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:e748106c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 candesartan cilexetil targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:e748390c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:478 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 canrenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:e7486198-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:480 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capecitabine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:e74886e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:e748b008-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e748d8c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e74901a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:e7492b82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7495530-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:e7497db2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e749a652-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e749cf4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P44514 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Succinyl-diaminopimelate desuccinylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:e749f7f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q79MP6 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e74a2186-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q93T40 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Beta-lactamase II) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:e74a4a3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9K2N0 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Unclassified (Beta-lactamase class B VIM-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e74a7438-ac81-11ec-8b6b-0242ac110002 UniProtKB:C7C422 biolink:molecularly_interacts_with DrugCentral:484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 captopril targets Enzyme (Beta-lactamase NDM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e74a9d50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caramiphen targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.81']} DrugCentral uuid:e74ac62c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caramiphen targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e74aeec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caramiphen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e74b182a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caramiphen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:e74b40c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caramiphen targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:e74b6960-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carazolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.94']} DrugCentral uuid:e74b9264-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e74bbb22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e74be3cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e74c0c76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carazolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:e74c35b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carazolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:e74c5e92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:e74c86ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:e74caf8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e74cd8ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.577']} DrugCentral uuid:e74d0158-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:e74d29da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:e74d52ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e74d7b9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:e74da432-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:e74dccbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e74df568-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e74e2006-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e74e48ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:e74e7150-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.74']} DrugCentral uuid:e74e9a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e74eca74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e74eca74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e74f066a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e74f066a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e74f4012-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:e74f4012-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:e74f783e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:e74f783e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:e74fb04c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e74fb04c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e74fe8fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:e74fe8fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:e7502cfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:e7502cfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:e7502cfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:e7502cfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:e7502cfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:e750835a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e750a830-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.495']} DrugCentral uuid:e750d0c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.125']} DrugCentral uuid:e750f97a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:e751238c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:e7514c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:e751783c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e751783c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e751783c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e751b504-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:e751b504-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:e751e8f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H461 biolink:molecularly_interacts_with DrugCentral:489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamazepine is allosteric modulator of GPCR (Frizzled-8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e752117a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenicillin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e7523a74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenicillin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e752651c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e752a0ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e752a0ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e752a0ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e752a0ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e752a0ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e752a0ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e752a0ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e75300ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenoxolone is inhibitor of Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:e753297a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:e7535206-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51661 biolink:molecularly_interacts_with DrugCentral:493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbenoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:e7537bb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxyverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.71']} DrugCentral uuid:e753a4fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxyverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:e753cdbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxyverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:e753f65c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxyverine targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:e7541ff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxyverine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:e7544a8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxyverine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:e754744c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxyverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e7549cec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbetocin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:e754c5c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbetocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.232']} DrugCentral uuid:e754ee7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbetocin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.149']} DrugCentral uuid:e7551730-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbidopa is inhibitor of Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:e7553b98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbidopa targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.168']} DrugCentral uuid:e75564c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbidopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:e7558d50-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbidopa targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e755b5e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22079 biolink:molecularly_interacts_with DrugCentral:497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbimazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e755def4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbimazole is inhibitor of Enzyme (Thyroid peroxidase) DrugCentral uuid:e75605a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbinoxamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:e7562c92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:502 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carboprost is agonist of GPCR (Prostaglandin F2-alpha receptor) DrugCentral uuid:e756551e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:e756551e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:e756a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e756a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e756a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e756a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e756a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e756a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e756a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e756fffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:510 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carubicin targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:e757246c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carmofur targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:e7574dca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carmofur targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.213']} DrugCentral uuid:e757766a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6P7S1 biolink:molecularly_interacts_with DrugCentral:511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carmofur targets Enzyme (Acid ceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:e7579f0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13510 biolink:molecularly_interacts_with DrugCentral:511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carmofur targets Enzyme (Acid ceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:e757c89a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6N5 biolink:molecularly_interacts_with DrugCentral:511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carmofur targets Unclassified (Sulfide:quinone oxidoreductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e757f338-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:512 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carmustine is inhibitor of Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:e7581caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50416 biolink:molecularly_interacts_with DrugCentral:513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levocarnitine targets Enzyme (Carnitine O-palmitoyltransferase 1, liver isoform) DrugCentral uuid:e758413a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levocarnitine targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:e7586a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18886 biolink:molecularly_interacts_with DrugCentral:513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levocarnitine targets Enzyme (Carnitine palmitoyltransferase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:e758941e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:515 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carperitide targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10']} DrugCentral uuid:e758bcaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18910 biolink:molecularly_interacts_with DrugCentral:515 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carperitide targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e758e522-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:516 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfenazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:e7590a48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:516 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfenazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:e7592ea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carpipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:e759573c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carpipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:e7598018-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:518 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e759aa16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:518 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:e759d2ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:518 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e759fb4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:518 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carprofen targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:e75a23ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:518 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carprofen targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:e75a4cf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:518 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carprofen targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:e75a759a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:520 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carteolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e75a9e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:520 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carteolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:e75ac6ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carumonam targets Enzyme (Peptidoglycan synthase FtsI) DrugCentral uuid:e75aec5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92736 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol is inhibitor of Ion channel (Ryanodine receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e75b14e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.742']} DrugCentral uuid:e75b3da4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:e75b666c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:e75b925e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.126']} DrugCentral uuid:e75bbe32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:e75be7e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:e75c10f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e75c3a7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.928']} DrugCentral uuid:e75c6314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.273']} DrugCentral uuid:e75c8baa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.476']} DrugCentral uuid:e75cb4d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:e75cdd80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:e75d06c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:e75d2f6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.152']} DrugCentral uuid:e75d59e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:e75d829e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:e75dab48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:e75dd3f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:e75dfd14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:e75e25f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:e75e4eb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.054']} DrugCentral uuid:e75e773a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e75ea1ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e75eca6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Ion channel (Potassium channel subfamily K member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e75ef2fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.706']} DrugCentral uuid:e75f1cb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:e75f475a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:e75f6fc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:e75f987c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.09']} DrugCentral uuid:e75fc158-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e75fe9ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:e7601270-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00206 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Membrane receptor (Toll-like receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e7603bec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:522 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carvedilol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:e7606590-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefacetrile targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e76089ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaclor targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e760ae74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaclor targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:e760eec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e760eec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e760eec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e760eec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e760eec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e760eec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e760eec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7614e60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46059 biolink:molecularly_interacts_with DrugCentral:526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefadroxil targets Transporter (Solute carrier family 15 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.14']} DrugCentral uuid:e7618e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7618e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7618e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7618e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7618e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7618e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7618e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e761ed8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46059 biolink:molecularly_interacts_with DrugCentral:527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefamandole targets Transporter (Solute carrier family 15 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.09']} DrugCentral uuid:e7622f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7622f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7622f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7622f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7622f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7622f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7622f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7628e1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefazolin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e762ccae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e762ccae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e762ccae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e762ccae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e762ccae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e762ccae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e762ccae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76330f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O54286 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir targets Enzyme (Pencillin binding protein 2a; Penicillin binding protein 2'; Penicillin binding protein, PBP2; Penicillin-binding protein 2; Penicillin-binding protein 2'; Peptidase) DrugCentral uuid:e7635552-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14TG6 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:e7637a28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:e763b9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e763b9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e763b9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e763b9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e763b9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e763b9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e763b9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76419f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefdinir targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e764428c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14TG6 biolink:molecularly_interacts_with DrugCentral:534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefditoren pivoxil targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:e76466d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q54906 biolink:molecularly_interacts_with DrugCentral:534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefditoren pivoxil targets Enzyme (Penicillin-binding protein) DrugCentral uuid:e764a42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e764a42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e764a42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e764a42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e764a42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e764a42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e764a42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76522c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76522c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76522c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76522c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76522c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76522c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76522c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e765839a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42971 biolink:molecularly_interacts_with DrugCentral:536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefetamet pivoxil targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:e765a802-ac81-11ec-8b6b-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefetamet pivoxil targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:e765cc6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefixime targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:e765f726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefixime targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e76636d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76636d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76636d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76636d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76636d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76636d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76636d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e766974e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19174 biolink:molecularly_interacts_with DrugCentral:537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefixime targets Enzyme (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e766d70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e766d70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e766d70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e766d70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e766d70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e766d70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e766d70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e767369a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmetazole targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e7677204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7677204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7677204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7677204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7677204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7677204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7677204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e767d21c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmetazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e767fad0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefmetazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e768235c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:e7684d6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e7687532-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e7689dbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:e768ddce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e768ddce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e768ddce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e768ddce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e768ddce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e768ddce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e768ddce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7693d5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoperazone targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e7697acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7697acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7697acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7697acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7697acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7697acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7697acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e769da76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceforanide targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e76a178e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76a178e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76a178e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76a178e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76a178e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76a178e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76a178e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76a7896-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotaxime is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:e76aa12c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.512']} DrugCentral uuid:e76aca26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.659']} DrugCentral uuid:e76af2a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotaxime targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e76b1bb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotaxime targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e76b4474-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.617']} DrugCentral uuid:e76b6ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e76b9726-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e76bbb98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e76be438-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e76c0f58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:e76c37e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e76c777c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76c777c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76c777c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76c777c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76c777c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76c777c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76c777c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76cd794-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotiam targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e76cfbf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotiam targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:e76d2528-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32241 biolink:molecularly_interacts_with DrugCentral:548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotiam targets GPCR (Vasoactive intestinal polypeptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:e76d64b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76d64b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76d64b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76d64b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76d64b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76d64b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76d64b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76dc6a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e76decf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) DrugCentral uuid:e76e114a-ac81-11ec-8b6b-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e76e39cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e76e62b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e76e8b3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:e76ecac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76ecac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76ecac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76ecac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76ecac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76ecac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76ecac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76f4344-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76f4344-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76f4344-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76f4344-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76f4344-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76f4344-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76f4344-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e76fa3b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefprozil targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e76fc846-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25098 biolink:molecularly_interacts_with DrugCentral:558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefsulodin targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:e76ff0c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefsulodin targets Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.522']} DrugCentral uuid:e770194a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefsulodin targets Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:e7704230-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefsulodin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e7706ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefsulodin targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:e770933e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefsulodin targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:e770bbb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5A7N4 biolink:molecularly_interacts_with DrugCentral:558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefsulodin targets Unclassified (tRNA 2'-phosphotransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e770e4ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:559 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftazidime is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.261']} DrugCentral uuid:e7710d82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:559 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftazidime is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.534']} DrugCentral uuid:e771362c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:559 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftazidime is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e7715eb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q1J5W5 biolink:molecularly_interacts_with DrugCentral:562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftibuten targets Enzyme (Penicillin-binding protein) DrugCentral uuid:e7718500-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60FU1 biolink:molecularly_interacts_with DrugCentral:562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftibuten targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:e771c10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e771c10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e771c10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e771c10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e771c10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e771c10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e771c10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e772228a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftizoxime targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e77246fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftizoxime targets Enzyme (Beta-lactamase) DrugCentral uuid:e772825c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e772825c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e772825c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e772825c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e772825c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e772825c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e772825c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e772e2f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:564 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftriaxone is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.142']} DrugCentral uuid:e7730b8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:564 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.513']} DrugCentral uuid:e7733436-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:564 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.744']} DrugCentral uuid:e7736028-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:564 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.213']} DrugCentral uuid:e77388aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:564 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftriaxone targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e773b1b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e773d62a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e773ff1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:e77427a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e774673e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774673e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774673e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774673e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774673e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774673e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774673e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774de8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774de8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774de8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774de8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774de8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774de8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e774de8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e775453c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e7756ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e77598de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.854']} DrugCentral uuid:e775c1ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.477']} DrugCentral uuid:e775ea96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e776134a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:e7763be0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.917']} DrugCentral uuid:e776652a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:e7768db6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e776b624-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.856']} DrugCentral uuid:e776de88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:e7770a48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e7773306-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:e7775b9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e7778482-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:e777ad86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e777d680-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:e777ff0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:e778287e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:e778518c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.033']} DrugCentral uuid:e7787a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:e778a3b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:e778ce78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:e778f768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:e7792012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:e779489e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:e7797198-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:e7799a24-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:e779c2a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.627']} DrugCentral uuid:e779eb50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.29']} DrugCentral uuid:e77a14fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:e77a3d8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8SPQ9 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Cyclooxygenase 2; Prostaglandin G/H synthase-2; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e77a660c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:e77a8ea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:e77aba12-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e77ae3d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e77b0cec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e77b35f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8HZR1 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:e77b5e7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e77b8712-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e77baf9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:e77bd91a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:e77c01a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:e77c2a46-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e77c52b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:e77c7bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:e77ca4a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e77cce38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:e77cf6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:e77d1fd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O78750 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e77d4868-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:e77d70fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:e77d9a20-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:e77dc36a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:e77dec0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:e77e14be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:e77e3e76-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:e77e6748-ac81-11ec-8b6b-0242ac110002 UniProtKB:O78749 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:e77e9060-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:e77eb8f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:e77ee1dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celecoxib targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:e77f0a68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celiprolol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e77f32ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celiprolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e77f5b8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 celiprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e77f84ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42971 biolink:molecularly_interacts_with DrugCentral:571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalexin targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:e77fa93c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16348 biolink:molecularly_interacts_with DrugCentral:571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalexin targets Transporter (Solute carrier family 15 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:e77fe8d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e77fe8d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e77fe8d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e77fe8d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e77fe8d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e77fe8d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e77fe8d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e78065b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e78065b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e78065b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e78065b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e78065b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e78065b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e78065b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e780c678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e780ef0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e781138a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e7813c16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:e78165b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin is inhibitor of Transporter (Solute carrier family 22 member 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e7818e32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e781b6b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35236 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:e781f836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e781f836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e781f836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e781f836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e781f836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e781f836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e781f836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e78257cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e7828094-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:e782a90c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:e782d210-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:e782fac4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:e78323dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:e7834c40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e78374c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:e7839d30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e783c774-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e783ebd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:e7841468-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:e7843cea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:e78465e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:e7848e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:e784b6fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e784df6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e78509cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:e7853230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e7855a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e785830c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:e785c68c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e785c68c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e785c68c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e785c68c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e785c68c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e785c68c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e785c68c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e786262c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefradine targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e7864aee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefradine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e78673e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefradine targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e786b38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e786b38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e786b38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e786b38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e786b38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e786b38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e786b38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7871514-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cerivastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:e7873990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cerivastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e78762f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cerivastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e7878c10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:578 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cerulenin targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e787b49c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00488 biolink:molecularly_interacts_with DrugCentral:578 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cerulenin targets Enzyme (Coagulation factor XIII A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e787dd1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:578 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cerulenin targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e78805fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceruletide is agonist of GPCR (Cholecystokinin receptor type A) DrugCentral uuid:e7882a8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:581 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetirizine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:e7885320-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:581 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetirizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:e7887bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:581 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetirizine targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.05']} DrugCentral uuid:e788a802-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetrorelix targets GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:e788d084-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetrorelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:e788f924-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cevimeline is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:e78921a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.983']} DrugCentral uuid:e7894c80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cevimeline is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:e7897836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.883']} DrugCentral uuid:e789a3a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.201']} DrugCentral uuid:e789cd68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorambucil targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:e789f662-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorambucil targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.93']} DrugCentral uuid:e78a1ee4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorambucil targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.026']} DrugCentral uuid:e78a47f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14091 biolink:molecularly_interacts_with DrugCentral:588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorambucil targets Enzyme (Cathepsin E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.78']} DrugCentral uuid:e78a713c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13443 biolink:molecularly_interacts_with DrugCentral:588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorambucil targets Enzyme (Disintegrin and metalloproteinase domain-containing protein 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e78a99b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:589 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloramphenicol targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:e78ac22c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62580 biolink:molecularly_interacts_with DrugCentral:589 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloramphenicol targets Enzyme (Chloramphenicol acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e78aeaa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:589 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloramphenicol targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:e78b145c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q88N29 biolink:molecularly_interacts_with DrugCentral:589 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloramphenicol targets Unclassified (Probable HTH-type transcriptional regulator TtgR) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:e78b3de2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorcyclizine targets Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e78b6678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.682']} DrugCentral uuid:e78b8f18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:e78bb81c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e78be0a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:e78c0948-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e78c31e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e78c5b3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21761 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e78c8bac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:e78c8bac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:e78c8bac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:e78cd364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:e78cd364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:e78cd364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:e78d2076-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:e78d2076-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:e78d2076-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:e78d67e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:e78d67e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:e78d67e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:e78db2b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:e78db2b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:e78db2b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78e2d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e78f1494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e78f1494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e78f1494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e78f1494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e78f1494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e78f1494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e78f7a74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e78f7a74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e78fb200-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e78fb200-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e78fe6f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorhexidine targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e7901006-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorhexidine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e790389c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e7906114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorhexidine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e7908aa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e790b33a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorhexidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:e790dbb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorhexidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e7910434-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7912d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorhexidine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e791557e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15056 biolink:molecularly_interacts_with DrugCentral:597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorhexidine targets Enzyme (Synaptojanin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e7917e0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlormadinone targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:e791a682-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlormadinone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.764']} DrugCentral uuid:e791cf90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlormadinone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:e791f7fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlormadinone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:e792209e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlormadinone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.163']} DrugCentral uuid:e79250d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e79250d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e79250d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e7928ed0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroprocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:e792b61c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:606 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloropyramine targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:e792df02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:e7930874-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e79330ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e79359fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:e793827c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e793aca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:e793d54c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:e793fde2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e7942678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:e79451e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e7947d4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:e794a5ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e794ceac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e794f71a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05227 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Cytosolic other (Histidine-rich protein PFHRP-II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e7951f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:e7954800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e7957154-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e79599b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e795c262-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N6S8 biolink:molecularly_interacts_with DrugCentral:607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroquine targets Enzyme (Cysteine proteinase falcipain 2a) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e795ead0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorothiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:e79610a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['5.43']} DrugCentral uuid:e7963c06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorotrianisene targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:e7966078-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorotrianisene is modulator of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:e7968558-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroxine targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:e796ae34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroxine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e796d6c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroxine targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e796ff60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroxine targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:e79727c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15296 biolink:molecularly_interacts_with DrugCentral:611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroxine targets Enzyme (Arachidonate 15-lipoxygenase, type II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:e79750e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e7977968-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.818']} DrugCentral uuid:e797a1d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:e797cb5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:e797f67c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:e7982002-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.967']} DrugCentral uuid:e79849ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.06']} DrugCentral uuid:e7987250-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e798a3ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e798a3ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e798a3ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e798e2bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e7990b5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96JM7 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Unclassified (Lethal(3)malignant brain tumor-like protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:e799347e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05BQ5 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Unclassified (MBT domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:e7995d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:e799858c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.842']} DrugCentral uuid:e799ae22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphenamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.975']} DrugCentral uuid:e799d988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphentermine is substrate of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.471']} DrugCentral uuid:e79a0282-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorphentermine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.404']} DrugCentral uuid:e79a2b04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:619 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorproethazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:e79a5408-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:619 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorproethazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.987']} DrugCentral uuid:e79a7c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:619 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorproethazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:e79aa53e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.233']} DrugCentral uuid:e79acdac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:e79af6d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:e79b1f64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e79b47fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.724']} DrugCentral uuid:e79b7072-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:e79b9bce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e79bc6a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:e79bef34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:e79c17de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:e79c40e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e79c696e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e79c91f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e79cba86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:e79ce3b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:e79d0c48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.553']} DrugCentral uuid:e79d34d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e79d5f0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e79d89b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e79db238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e79ddaba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.759']} DrugCentral uuid:e79e04d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:e79e2d62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:e79e55ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.746']} DrugCentral uuid:e79e7e8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.251']} DrugCentral uuid:e79ea7ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:e79ed03c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:e79ef8be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:e79f212c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.827']} DrugCentral uuid:e79f4c92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.345']} DrugCentral uuid:e79f7596-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e79f9f6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:e79fc7f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:e79ff110-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:e7a01a28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.708']} DrugCentral uuid:e7a042b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:e7a06c58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.092']} DrugCentral uuid:e7a094ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:e7a0c568-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:e7a0c568-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:e7a0c568-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:e7a105b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.133']} DrugCentral uuid:e7a13138-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.928']} DrugCentral uuid:e7a15ca8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.463']} DrugCentral uuid:e7a18714-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:e7a1b00e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:e7a1d8a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.061']} DrugCentral uuid:e7a20126-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.713']} DrugCentral uuid:e7a229a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.569']} DrugCentral uuid:e7a252ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e7a27b6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:e7a2a3ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.043']} DrugCentral uuid:e7a2cc3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e7a2f6e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.797']} DrugCentral uuid:e7a31f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.305']} DrugCentral uuid:e7a347f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:e7a3716e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.835']} DrugCentral uuid:e7a39a90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:e7a3c43e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.673']} DrugCentral uuid:e7a3ece8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.777']} DrugCentral uuid:e7a4163c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:e7a43eaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e7a467d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:e7a4906c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:e7a4b9fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:e7a4e292-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e7a50b1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:e7a533be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e7a55ca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35433 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7a58526-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e7a5add0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e7a5d634-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.854']} DrugCentral uuid:e7a5ff60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7a63fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7a63fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7a63fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7a63fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7a63fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7a63fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7a63fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7a6c594-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7a6c594-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7a6c594-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7a6c594-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7a6c594-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7a6c594-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7a6c594-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7a742e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e7a742e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e7a742e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e7a742e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e7a742e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e7a79ca8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e7a79ca8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e7a7e078-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e7a7e078-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e7a7e078-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e7a7e078-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e7a7e078-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e7a83f5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e7a83f5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e7a83f5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e7a889b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:e7a889b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:e7a889b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:e7a8e3d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e7a8e3d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e7a8e3d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e7a8e3d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e7a8e3d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e7a8e3d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e7a8e3d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e7a8e3d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e7a95cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:e7a98540-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e7a9aebc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04925 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Unclassified (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e7a9d752-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17405 biolink:molecularly_interacts_with DrugCentral:621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpromazine targets Enzyme (Sphingomyelin phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e7a9ffd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:622 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpropamide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e7aa2d6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:622 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpropamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:e7aa2d6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:622 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorpropamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:e7aa6406-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:e7aa8cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:e7aab55a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.367']} DrugCentral uuid:e7aade86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e7ab0726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:e7ab2fd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e7ab5848-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:e7ab817e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:e7aba9ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:e7abd264-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:e7abfae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:e7ac27dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:e7ac51a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.194']} DrugCentral uuid:e7ac7a5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:e7aca356-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:e7accc0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.97']} DrugCentral uuid:e7acf518-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorprothixene targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:e7ad1db8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortetracycline targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e7ad4748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortetracycline targets Surface antigen (Major prion protein) DrugCentral uuid:e7ad6ba6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM07 biolink:molecularly_interacts_with DrugCentral:624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortetracycline targets Enzyme (Protein-arginine deiminase type-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e7ad941e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.56']} DrugCentral uuid:e7adbcbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:e7ade2ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e7ae0bba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:e7ae345a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:e7ae5cfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:e7ae85fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:e7aeae94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e7aed72a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e7aeffca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e7af2982-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:e7af5218-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:e7af7ac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:625 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e7afa362-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorzoxazone is activator of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e7afccac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e7aff52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29475 biolink:molecularly_interacts_with DrugCentral:626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e7b01ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29474 biolink:molecularly_interacts_with DrugCentral:626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, endothelial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:e7b04786-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29476 biolink:molecularly_interacts_with DrugCentral:626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.554']} DrugCentral uuid:e7b07008-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorzoxazone is activator of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:e7b09934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorzoxazone is opener of Ion channel (Calcium-activated potassium channel subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.523']} DrugCentral uuid:e7b0c198-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:e7b0eaba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:e7b11350-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:e7b13be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e7b16490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:e7b18e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e7b1b6c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:e7b1df56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.31']} DrugCentral uuid:e7b20800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e7b23226-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:e7b25ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e7b2837a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:e7b2ac10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:e7b2d5fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:e7b2fea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:e7b3274e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:e7b34fbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e7b37c12-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:e7b3a50c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e7b3cda2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e7b3f728-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:e7b420a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96394 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Arginase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7b4493a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:e7b471bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4QEW7 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:e7b49af2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:e7b4c3a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:e7b4ec50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:629 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cianidanol targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e7b514d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cibenzoline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:e7b53e26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cibenzoline targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) DrugCentral uuid:e7b562ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cibenzoline targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:e7b58b38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:e7b5b3ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:e7b5dcdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicaprost targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e7b6057c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e7b62e1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicaprost targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:e7b656bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicaprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:e7b67ffc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicaprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:e7b6a8a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicaprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:e7b6d146-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicaprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e7b6f9d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e7b737d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7b737d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7b737d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7b737d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7b737d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7b737d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7b737d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:e7b798c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclesonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:e7b7c2fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:636 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclopirox is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e7b7ebbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:636 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclopirox is inhibitor of Unclassified (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e7b81452-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:636 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclopirox targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e7b83d7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicloprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e7b86614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cicloprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e7b88ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cidofovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:e7b8b31c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16444 biolink:molecularly_interacts_with DrugCentral:640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cilastatin is inhibitor of Enzyme (Dipeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:e7b8dd38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22412 biolink:molecularly_interacts_with DrugCentral:640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cilastatin targets Enzyme (Dipeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:e7b90902-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cilazapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e7b933e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02294 biolink:molecularly_interacts_with DrugCentral:642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cilnidipine is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e7b960d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cilnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e7b960d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cilnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e7b98fb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cilostazol is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e7b9b83e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cilostazol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e7b9e0d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cilostazol is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:e7ba09ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:645 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cimetidine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:e7ba328c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:645 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cimetidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:e7ba5b40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:645 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cimetidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:e7ba83fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:645 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cimetidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e7baadb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:645 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cimetidine is inhibitor of Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e7bad656-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:645 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cimetidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:e7baff6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:647 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinacalcet targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e7bb28a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:647 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinacalcet targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:e7bb519e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:647 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinacalcet is positive allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e7bb7a02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31424 biolink:molecularly_interacts_with DrugCentral:647 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinacalcet is allosteric modulator of GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:e7bba298-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:648 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinalukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:e7bbcc32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:648 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinalukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) DrugCentral uuid:e7bbf162-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.035']} DrugCentral uuid:e7bc1a02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:e7bc42ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.777']} DrugCentral uuid:e7bc6b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:e7bc964e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:e7bcbf02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.552']} DrugCentral uuid:e7bce798-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.208']} DrugCentral uuid:e7bd1038-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.987']} DrugCentral uuid:e7bd3946-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.333']} DrugCentral uuid:e7bd631c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:e7bd8bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:e7bdb54c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.064']} DrugCentral uuid:e7bdddec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.849']} DrugCentral uuid:e7be0696-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:e7be2f4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:e7be58a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:e7be81ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:e7beaaec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:e7bed396-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.885']} DrugCentral uuid:e7befc90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.242']} DrugCentral uuid:e7bf2512-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.299']} DrugCentral uuid:e7bf4dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.793']} DrugCentral uuid:e7bf763e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e7bf9fce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.97']} DrugCentral uuid:e7bfd12e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:e7bfd12e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:e7bfd12e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:e7c0103a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinoxacin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:e7c03f2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:e7c03f2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:e7c06e18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e7c0969a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AFI2 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:e7c0bf3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q45066 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:e7c0e834-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e7c110d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e7c13974-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:e7c162b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c1c498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e7c2acc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e7c2acc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e7c2e0b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37340 biolink:molecularly_interacts_with DrugCentral:659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciprofloxacin targets Unclassified (Multidrug resistance protein mdtK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:e7c3093e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:e7c332ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e7c35b6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e7c383e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:e7c3ac72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.379']} DrugCentral uuid:e7c3d652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.19']} DrugCentral uuid:e7c40226-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:e7c42dfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:e7c45730-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e7c4803e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:e7c4a906-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:e7c4d1b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.396']} DrugCentral uuid:e7c4fa46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e7c52368-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.281']} DrugCentral uuid:e7c54bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:e7c5750c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.947']} DrugCentral uuid:e7c59da2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.155']} DrugCentral uuid:e7c5c980-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:e7c5f374-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.472']} DrugCentral uuid:e7c61c0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:e7c64518-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.063']} DrugCentral uuid:e7c66e12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:e7c6973e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e7c6bfde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e7c6e914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e7c711b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e7c73a5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e7c762ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e7c78dd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:e7c7ba6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e7c7ba6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e7c7fe12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:e7c7fe12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:e7c7fe12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:e7c7fe12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:e7c7fe12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:e7c86014-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e7c86014-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e7c86014-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e7c86014-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e7c8b32a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e7c8b32a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e7c8b32a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e7c8fb3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:e7c8fb3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:e7c8fb3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:e7c93a8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e7c96cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e7c96cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e7c96cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e7c9abe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.777']} DrugCentral uuid:e7c9d480-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e7c9fd84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.935']} DrugCentral uuid:e7ca262e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e7ca4ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.191']} DrugCentral uuid:e7ca776e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.931']} DrugCentral uuid:e7caa0cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:e7cac9da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.456']} DrugCentral uuid:e7caf27a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:e7cb1afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:e7cb445a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:e7cb6d04-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:e7cb957c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:e7cbbe6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:e7cbe6ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e7cc1006-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e7cc39e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e7cc6308-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e7cc8c84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e7ccb524-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:e7ccddc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q48255 biolink:molecularly_interacts_with DrugCentral:666 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citric acid targets Enzyme (3-dehydroquinate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e7cd0790-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15474 biolink:molecularly_interacts_with DrugCentral:666 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citric acid targets Enzyme (3-dehydroquinate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e7cd3044-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EPK8 biolink:molecularly_interacts_with DrugCentral:666 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 citric acid is activator of Ion channel (Transient receptor potential cation channel subfamily V member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e7cd58b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cladribine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:e7cd7d24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cladribine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.441']} DrugCentral uuid:e7cda682-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cladribine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e7cdcf36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cladribine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:e7cdf7c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:668 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clarithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:e7ce203a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'MPC', 'has_quantitative_value': ['8.719']} DrugCentral uuid:e7ce49de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.187']} DrugCentral uuid:e7ce7260-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e7ce9aec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59401 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e7cec378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e7ceef4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e7cf1a26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13661 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase OXA-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e7cf42bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e7cf6c06-ac81-11ec-8b6b-0242ac110002 UniProtKB:A4KCT8 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e7cf9488-ac81-11ec-8b6b-0242ac110002 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:e7cfbd0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:e7cfe582-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e7d00e5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9F663 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Carbepenem-hydrolyzing beta-lactamase KPC) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e7d036e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:e7d05f44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e7d087d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD64 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:e7d0b37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6GWS8 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:e7d0dc30-ac81-11ec-8b6b-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e7d104c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0ZX81 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:e7d12d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4TVR4 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e7d156a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e7d17f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2XPY6 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e7d1a82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A3M1 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e7d1d0cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e7d1f9bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e7d223f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q670S6 biolink:molecularly_interacts_with DrugCentral:669 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:e7d24c78-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:e7d275fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e7d2a07e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7d2c914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:e7d2f1be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:e7d31b12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e7d34394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:e7d36c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e7d394d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:e7d3c5b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7d3c5b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7d3c5b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7d40cc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:e7d40cc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:e7d40cc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:e7d44d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.115']} DrugCentral uuid:e7d4793a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:e7d4a1e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:e7d4caa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:e7d4f3ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:e7d51c64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.514']} DrugCentral uuid:e7d54590-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.036']} DrugCentral uuid:e7d56e3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:e7d5975c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:e7d5c006-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:e7d5e8ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:e7d61150-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.604']} DrugCentral uuid:e7d63d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:e7d66902-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:e7d69198-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:e7d6bad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.703']} DrugCentral uuid:e7d6e382-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.084']} DrugCentral uuid:e7d70c22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.558']} DrugCentral uuid:e7d734c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:e7d75dda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:e7d78670-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.269']} DrugCentral uuid:e7d7aef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e7d7d8be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:e7d80348-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:e7d82f9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:e7d85b36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:e7d8850c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:e7d8ae6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:e7d8d7a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e7d90036-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemastine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e7d928cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemizole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.396']} DrugCentral uuid:e7d951da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemizole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e7d97a66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN4 biolink:molecularly_interacts_with DrugCentral:672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e7d9a31a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e7d9cce6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13507 biolink:molecularly_interacts_with DrugCentral:672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e7d9f888-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y210 biolink:molecularly_interacts_with DrugCentral:672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e7da2452-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clenbuterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:e7da4ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clenbuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e7da77fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clenbuterol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:e7daa09e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clenbuterol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:e7dac948-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clenbuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:e7daf1f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:674 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clevidipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:e7db16e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:674 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clevidipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:e7db3b76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:676 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:e7db6006-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:676 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:e7db8892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:678 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clindamycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:e7dbaf3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:681 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clioquinol targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:e7dbda22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:681 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clioquinol targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:e7dc02cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:681 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clioquinol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:e7dc2bee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:681 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clioquinol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e7dc5d12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e7dc5d12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e7dc5d12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e7dc9660-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05141 biolink:molecularly_interacts_with DrugCentral:690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clodronic acid targets Enzyme (ADP/ATP translocase 2) DrugCentral uuid:e7dcbab4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12235 biolink:molecularly_interacts_with DrugCentral:690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clodronic acid targets Transporter (ADP/ATP translocase 1) DrugCentral uuid:e7dcdf8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12236 biolink:molecularly_interacts_with DrugCentral:690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clodronic acid targets Enzyme (ADP/ATP translocase 3) DrugCentral uuid:e7dd03f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clodronic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) DrugCentral uuid:e7dd2882-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BYT1 biolink:molecularly_interacts_with DrugCentral:690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clodronic acid is inhibitor of Transporter (Solute carrier family 17 member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:e7dd5118-ac81-11ec-8b6b-0242ac110002 UniProtKB:B1LRJ1 biolink:molecularly_interacts_with DrugCentral:690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clodronic acid targets Unclassified (Type IV secretion-like conjugative transfer relaxase protein TraI) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e7dd7b20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:691 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofarabine is inhibitor of Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:e7dda0f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:691 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofarabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7ddc9a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:691 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofarabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7ddf230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P60891 biolink:molecularly_interacts_with DrugCentral:691 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofarabine targets Kinase (Ribose-phosphate pyrophosphokinase 1) DrugCentral uuid:e7de174c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HA47 biolink:molecularly_interacts_with DrugCentral:691 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofarabine targets Kinase (Uridine-cytidine kinase 1) DrugCentral uuid:e7de3c4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BZX2 biolink:molecularly_interacts_with DrugCentral:691 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofarabine targets Kinase (Uridine-cytidine kinase 2) DrugCentral uuid:e7de60da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:691 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofarabine targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:e7de8966-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L2G3 biolink:molecularly_interacts_with DrugCentral:692 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofazimine targets Enzyme (Uncharacterized oxidoreductase CzcO-like) DrugCentral uuid:e7deaebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:692 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofazimine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e7ded740-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:694 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:e7defff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:694 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e7df286c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofibric acid targets Enzyme (Lipoprotein lipase) DrugCentral uuid:e7df4e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofibric acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e7df770e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofibric acid targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:e7df9f90-ac81-11ec-8b6b-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:698 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clometacin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e7dfc812-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.461']} DrugCentral uuid:e7dff13e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.455']} DrugCentral uuid:e7e019e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e7e0429c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.745']} DrugCentral uuid:e7e06b32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e7e0954e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:e7e0bdf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:e7e0e6b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.025']} DrugCentral uuid:e7e10f56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.062']} DrugCentral uuid:e7e13b48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:e7e16456-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:e7e18d0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.142']} DrugCentral uuid:e7e1b622-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:e7e1deae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.187']} DrugCentral uuid:e7e20758-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.407']} DrugCentral uuid:e7e22fe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.889']} DrugCentral uuid:e7e25906-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.358']} DrugCentral uuid:e7e281a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:e7e2aa50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.896']} DrugCentral uuid:e7e2d2dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.371']} DrugCentral uuid:e7e2fcbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.668']} DrugCentral uuid:e7e3255c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.206']} DrugCentral uuid:e7e34e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e7e377aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.519']} DrugCentral uuid:e7e3a0e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:e7e3ca02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.979']} DrugCentral uuid:e7e3f28e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e7e41b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.778']} DrugCentral uuid:e7e44478-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:e7e46d22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:e7e4969e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:e7e4bf52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:e7e4eac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomifene targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e7e51362-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:e7e53bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:e7e56574-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:e7e58e00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.243']} DrugCentral uuid:e7e5b6aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.703']} DrugCentral uuid:e7e5df4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e7e60876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:e7e6310c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:e7e65a38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:e7e682d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:e7e6ad80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:e7e6d65c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:e7e6fefc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.412']} DrugCentral uuid:e7e72792-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.007']} DrugCentral uuid:e7e750a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.696']} DrugCentral uuid:e7e7794a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:e7e7a1ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:e7e7ca76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:e7e7f3ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:e7e81c60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e7e844ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.319']} DrugCentral uuid:e7e86e18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:e7e89ad2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:e7e8c570-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:e7e8ee1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:e7e916f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Enzyme (Glutathione S-transferase P) DrugCentral uuid:e7e93b68-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:e7e963fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e7e98dca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:e7e9b7aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.937']} DrugCentral uuid:e7e9e0cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:e7ea0958-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e7ea320c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e7ea5c28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:e7ea84a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eadf22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e7eba826-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e7eba826-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e7eba826-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e7eba826-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e7ebfa38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:e7ebfa38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:e7ebfa38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:e7ec4254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:e7ec4254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:e7ec4254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:e7ec8174-ac81-11ec-8b6b-0242ac110002 UniProtKB:P39051 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e7ecaa14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clomipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e7ecdad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:e7ecdad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:e7ecdad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ed5450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e7ee3d98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7ee3d98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7ee3d98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7ee3d98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7ee3d98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7ee3d98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7eed8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e7efac46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e7efd874-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e7f002d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e7f02bb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e7f0545c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e7f07d60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e7f0a68c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e7f0cf2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e7f0f844-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:e7f120f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:e7f14998-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:e7f17260-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:e7f19c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e7f1c710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e7f1ef92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.41']} DrugCentral uuid:e7f218c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:e7f241ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e7f26a4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e7f292ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:e7f2bb84-ac81-11ec-8b6b-0242ac110002 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e7f2e492-ac81-11ec-8b6b-0242ac110002 UniProtKB:O88703 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e7f30e0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.796']} DrugCentral uuid:e7f3367c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:e7f366d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e7f366d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e7f366d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e7f3a6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70507 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e7f3cfa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:e7f3f83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clonixin targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e7f421d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloperastine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:e7f44a6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clopidogrel targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.524']} DrugCentral uuid:e7f47320-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clopidogrel is antagonist of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e7f49bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clopidogrel targets Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e7f4cd0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:e7f4cd0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:e7f4cd0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:e7f51424-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:e7f51424-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:e7f51424-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:e7f557e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:e7f557e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:e7f557e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:e7f59bf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:e7f59bf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:e7f59bf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:e7f5d40e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:714 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.825']} DrugCentral uuid:e7f5fcf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:714 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:e7f6268e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:e7f64f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:e7f6786e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e7f6b04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:e7f6b04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:e7f6b04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:e7f6b04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:e7f6b04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:e7f70da6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:e7f70da6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:e7f70da6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:e7f74dca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.186']} DrugCentral uuid:e7f77656-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.379']} DrugCentral uuid:e7f79ee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:e7f7c7d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.136']} DrugCentral uuid:e7f7f07c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:e7f81930-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.391']} DrugCentral uuid:e7f84248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:e7f86c0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.351']} DrugCentral uuid:e7f894a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e7f8bd22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:e7f8e590-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.174']} DrugCentral uuid:e7f90f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.514']} DrugCentral uuid:e7f937b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.104']} DrugCentral uuid:e7f9606a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.995']} DrugCentral uuid:e7f98a54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:e7f9b312-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.132']} DrugCentral uuid:e7f9dbb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e7fa0466-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.235']} DrugCentral uuid:e7fa2d92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.429']} DrugCentral uuid:e7fa575e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.046']} DrugCentral uuid:e7fa7ffe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.466']} DrugCentral uuid:e7faa8a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.294']} DrugCentral uuid:e7fad35a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:e7fafbfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.287']} DrugCentral uuid:e7fb2490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.677']} DrugCentral uuid:e7fb4d44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.785']} DrugCentral uuid:e7fb7670-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:e7fb9f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.267']} DrugCentral uuid:e7fbc828-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:e7fbf0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.106']} DrugCentral uuid:e7fc1a08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:e7fc42a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:e7fc6b20-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:e7fc8f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.156']} DrugCentral uuid:e7fcb936-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.521']} DrugCentral uuid:e7fce1cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.132']} DrugCentral uuid:e7fd0a44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.598']} DrugCentral uuid:e7fd335c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:e7fd57ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:e7fd8050-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e7fda9ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.712']} DrugCentral uuid:e7fdd366-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:e7fdfbe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.645']} DrugCentral uuid:e7fe250a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:e7fe4d78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:e7fe774e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.159']} DrugCentral uuid:e7fe9fe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e7fec870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.058']} DrugCentral uuid:e7fef106-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.089']} DrugCentral uuid:e7ff1a64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e7ff42e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:e7ff6b7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.497']} DrugCentral uuid:e7ff9412-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.178']} DrugCentral uuid:e7ffbd3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.854']} DrugCentral uuid:e7ffe5ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e8000e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e800382c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:e8006446-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.471']} DrugCentral uuid:e8008d54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.112']} DrugCentral uuid:e800b5fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.906']} DrugCentral uuid:e800df16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e8010798-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:e8013024-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.942']} DrugCentral uuid:e80158a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:e80181b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:e801ab3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e801d3e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e801fc7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:e8022768-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.99']} DrugCentral uuid:e802503a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:e8027948-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:e802a1e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e802cace-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:e802f350-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPN5 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Putative cytochrome P450 130) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:e8031bf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00766 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Alpha-chymotrypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8034486-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:e8036eac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e803974c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clotrimazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e803bfce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e803e4f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e8040fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:A4ZYU9 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e8043846-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3S5C3 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin targets Transporter (Efflux transporter; SugE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e80460d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q48435 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e80489ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62594 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e804c1c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e804c1c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e804c1c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e804c1c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e804c1c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e8050e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:721 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxazolam targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:e8053746-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:e8055fbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.783']} DrugCentral uuid:e8058962-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e805b220-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:e805debc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.154']} DrugCentral uuid:e806077a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:e8063088-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:e806598c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:e806824a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:e806ab12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e806d3d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e806fd24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:e80725c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e8074e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:e80776fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.78']} DrugCentral uuid:e807a1b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e807cd76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e807f6ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:e8081f6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.594']} DrugCentral uuid:e8084864-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:e808710e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:e80899b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:e808c230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.181']} DrugCentral uuid:e808eb66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e80913f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.591']} DrugCentral uuid:e8093c74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:e80965aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.792']} DrugCentral uuid:e8098fa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.356']} DrugCentral uuid:e809b83e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e809e0e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e80a09ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e80a332c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:e80a5bb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e80a8462-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e80aada2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e80ad64c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:e80afeec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22310 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Enzyme (UDP-glucuronosyltransferase 1-4) {'has_attribute_type': 'IAO:0000004', 'name': 'app Km', 'has_quantitative_value': ['4.208']} DrugCentral uuid:e80b2764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e80b5248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e80b7af2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e80ba392-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.445']} DrugCentral uuid:e80bcd5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e80bf66c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:e80c1f02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e80c47ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:e80c70ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:e80c9982-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:e80cc218-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:e80ceb1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:e80d14f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:e80d3d88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e80d6628-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e80d8eb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:e80db920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:e80de1c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:e80e0a6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:e80e3300-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:e80e5c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:e80e84c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e80ead4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e80ed5f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e80f0212-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e80f2b2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:e80f53d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e80f7ca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:e80fa56e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e80fcde6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e80ff6ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:e8102016-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e8104992-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:e81072b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:e8109b54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:e810c5b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q91ZY2 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:e810ee7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q91ZY1 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e8111afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e8111afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e8115ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e8115ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e8115ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e8115ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e8115ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e811c254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e811c254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e811c254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e811c254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e812157e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e812157e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e812157e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e81258ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:e81258ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:e8129dbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:e8129dbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:e8129dbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:e8129dbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:e8129dbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:e812fb9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:e812fb9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:e812fb9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:e8135628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e8135628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e8135628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e8135628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e8135628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e8135628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e8135628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e8135628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e813d6fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e813d6fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e813d6fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e8141644-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e8143eee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e81468d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.21']} DrugCentral uuid:e8149420-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP23 biolink:molecularly_interacts_with DrugCentral:722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clozapine targets Cytosolic other (Calmodulin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e814bc98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e814e114-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e8150a22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e81532a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:e8155cde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:e8158592-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:e815aedc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.67']} DrugCentral uuid:e815d77c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e8160058-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e8162902-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:e81654d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:e8167f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UI33 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Ion channel (Sodium channel protein type 11 subunit alpha) DrugCentral uuid:e816a38c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e816cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:e816f0da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:e8171966-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:e8174206-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:e8176a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:e81794d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e817bd4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:e817e9d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e817e9d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e81828c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:e81828c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:e81828c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:e81867d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27922 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transporter (Dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:e8189066-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GJT6 biolink:molecularly_interacts_with DrugCentral:723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cocaine targets Transporter (Dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e818b960-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 codeine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:e818e296-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 codeine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:e8190b54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 codeine is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:e8193f84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e8193f84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e8193f84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e8193f84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e8198aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:e819b338-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.801']} DrugCentral uuid:e819dbba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:e81a0342-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.49']} DrugCentral uuid:e81a2bd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.194']} DrugCentral uuid:e81a545a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07437 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine is inhibitor of Structural (Tubulin beta chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e81a7d54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e81aa5d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02550 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e81acf98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6B856 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Structural (Tubulin beta-2B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e81af82e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine is inhibitor of Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e81b222c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q27957 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Unclassified (Tubulin polymerization-promoting protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:e81b4aa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68371 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Structural (Tubulin beta-4B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e81b7b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e81b7b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e81b7b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e81bbfb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e81bbfb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e81bf3a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08828 biolink:molecularly_interacts_with DrugCentral:729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colforsin daropate targets Enzyme (Adenylate cyclase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:e81c23f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e81c23f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e81c23f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e81c6362-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11166 biolink:molecularly_interacts_with DrugCentral:729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colforsin daropate targets Transporter (Solute carrier family 2, facilitated glucose transporter member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e81c8bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19754 biolink:molecularly_interacts_with DrugCentral:729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colforsin daropate targets Enzyme (Adenylate cyclase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:e81cb484-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 conivaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:e81cddc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 conivaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:e81d077c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 conivaptan targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:e81d3008-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 conivaptan targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e81d58bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 conivaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:e81d8166-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cortisone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:e81dadc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cortisone acetate targets Cytosolic other (Annexin A1) DrugCentral uuid:e81dd29c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cortisone acetate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e81dfb50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cortisone acetate targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:e81e2440-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cortisone acetate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:e81e4d76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cortisone acetate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:e81e79e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cortisone acetate targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e81e79e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cortisone acetate targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e81eaf14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:736 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cortivazol is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:e81ed41c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:737 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cotinine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:e81ef884-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e81f212e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:e81f49ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:e81f7494-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e81f9d52-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e81fc5e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e81fee88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:e8201796-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:e82041da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:e8206a98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e82093b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:e820bc64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e820e504-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:e8210d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e82137b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e82160a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q33BM1 biolink:molecularly_interacts_with DrugCentral:741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cromoglicic acid targets GPCR (G protein-coupled receptor GPR35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:e8218928-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES90 biolink:molecularly_interacts_with DrugCentral:741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cromoglicic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:e821b196-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cromoglicic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:e821daa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25815 biolink:molecularly_interacts_with DrugCentral:741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cromoglicic acid targets Cytosolic other (Protein S100-P) DrugCentral uuid:e821fef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e822278e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.237']} DrugCentral uuid:e822502e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e822798c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:e822a308-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:e822cba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e822f43e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.602']} DrugCentral uuid:e8231e32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:e82346be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:e8236f5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:e8239862-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:e823c166-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:e823e9fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyamemazine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.531']} DrugCentral uuid:e82412b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.235']} DrugCentral uuid:e8243b5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:e82464ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.623']} DrugCentral uuid:e8248d58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:e824b602-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.993']} DrugCentral uuid:e824e0b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.353']} DrugCentral uuid:e8250c74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:e825350a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.385']} DrugCentral uuid:e8255da0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.799']} DrugCentral uuid:e8258690-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.924']} DrugCentral uuid:e825af4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.342']} DrugCentral uuid:e825d7c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:e826005c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.206']} DrugCentral uuid:e8262aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:e8265340-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:e82677c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:e826a142-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.728']} DrugCentral uuid:e826cce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:e826f5ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:e8271f0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.541']} DrugCentral uuid:e82747b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.812']} DrugCentral uuid:e82770c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:e8279976-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:e827c216-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:e827eb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.829']} DrugCentral uuid:e82813f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:e8283c6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:e8286504-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.222']} DrugCentral uuid:e8288f16-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.509']} DrugCentral uuid:e828ba04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclobenzaprine targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:e828e2c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:753 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclofenil targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:e8290b4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:753 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclofenil targets Nuclear other (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:e8293452-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e8295cf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:e82985ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloguanil is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:e829ae5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:e829dbe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:e82a047c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:e82a2d8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:e82a5648-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclopentolate is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:e82a7db2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclophosphamide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:e82aa71a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82acfba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:e82af8a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82b2122-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82b49c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:e82b72d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82b9bfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WQA8 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Enzyme (Alanine racemase) DrugCentral uuid:e82bc050-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05586 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:e82be8e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60391 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82c12b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WP31 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine is inhibitor of Enzyme (D-alanine--D-alanine ligase) DrugCentral uuid:e82c38aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WQA9 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine is inhibitor of Enzyme (Alanine racemase) DrugCentral uuid:e82c600a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:e82c8bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:e82ccc0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82ccc0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82ccc0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82ccc0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82ccc0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82ccc0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82ccc0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e82d3822-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:e82d60b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:e82d89da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:e82db25c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:e82ddade-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e82e0496-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin is modulator of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:e82e2f3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:e82e57b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:e82e801a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e82ea8ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e82ed182-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:e82efa36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02790 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e82f22ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:e82f4bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23284 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.01']} DrugCentral uuid:e82f7466-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e82f9d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:e82fc59c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:e82fefc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08752 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:e8301862-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e83040ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e8306970-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e8309260-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JHG7 biolink:molecularly_interacts_with DrugCentral:760 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciclosporin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:e830baf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:e830df5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e83107cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:e831310c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclothiazide is allosteric modulator of Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:e8315998-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclothiazide is allosteric modulator of Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:e8318ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e8318ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e8318ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e8318ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e831deb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:762 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclovalone targets Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:e832073a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:762 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclovalone targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e8323034-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05412 biolink:molecularly_interacts_with DrugCentral:762 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclovalone targets Transcription factor (Transcription factor AP-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e8325942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cycrimine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:e8327d8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:e832a618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:e832ceae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:e832f7ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.855']} DrugCentral uuid:e8332084-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e83344ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:e8336d8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:e83396fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:e833bf8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.419']} DrugCentral uuid:e833e82a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.812']} DrugCentral uuid:e83410b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.652']} DrugCentral uuid:e83439a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e834623c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e8348adc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e834b372-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:e834dcda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:e835055c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.222']} DrugCentral uuid:e8352e74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:e8355818-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.185']} DrugCentral uuid:e83580ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e835a926-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e835d19e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e835fb60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:e8362414-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.559']} DrugCentral uuid:e8364caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:e8367540-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.733']} DrugCentral uuid:e8369e80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e836c716-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e836f768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:e836f768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:e836f768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:e8373228-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:e8375afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.899']} DrugCentral uuid:e8378390-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:e837ac94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:e837d5a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e837fe2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:e83826c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:e8384f5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e83878b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:e838a1e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34968 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e838ca70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:e838f310-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:e8391eee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e8395ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e8395ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e8395ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e8395ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e8395ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e839c13c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e839c13c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e839c13c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e839c13c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e839c13c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e83a1eca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e83a1eca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e83a1eca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e83a666e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:e83a666e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:e83a666e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:e83aa57a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WTS6 biolink:molecularly_interacts_with DrugCentral:765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproheptadine targets Enzyme (Histone-lysine N-methyltransferase SETD7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e83ace10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproterone acetate targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.053']} DrugCentral uuid:e83afa52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproterone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:e83b2388-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproterone acetate is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:e83b4c1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproterone acetate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.678']} DrugCentral uuid:e83b763a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproterone acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:e83b9ed0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproterone acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.315']} DrugCentral uuid:e83bc784-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyproterone acetate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e83bf01a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:769 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cysteine targets Transporter (Cystine/glutamate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:e83c195a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15309 biolink:molecularly_interacts_with DrugCentral:770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytarabine targets Enzyme (Prostatic acid phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'GI50', 'has_quantitative_value': ['7']} DrugCentral uuid:e83c41f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytarabine targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:e83c6a54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06746 biolink:molecularly_interacts_with DrugCentral:770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytarabine targets Enzyme (DNA polymerase beta) DrugCentral uuid:e83c9682-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:e83c9682-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:e83c9682-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:e83cd0fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00987 biolink:molecularly_interacts_with DrugCentral:770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytarabine targets Nuclear other (E3 ubiquitin-protein ligase Mdm2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e83cf9ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:773 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dacarbazine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.255']} DrugCentral uuid:e83d226e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14181 biolink:molecularly_interacts_with DrugCentral:773 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dacarbazine targets Enzyme (DNA polymerase alpha subunit B) DrugCentral uuid:e83d474e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62993 biolink:molecularly_interacts_with DrugCentral:774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dactinomycin targets Cytosolic other (Growth factor receptor-bound protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e83d6fda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dactinomycin targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e83d9884-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60631 biolink:molecularly_interacts_with DrugCentral:774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dactinomycin targets Cytosolic other (Growth factor receptor-bound protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e83dc124-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96IV0 biolink:molecularly_interacts_with DrugCentral:774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dactinomycin targets Enzyme (Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.05']} DrugCentral uuid:e83deafa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e83e139a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e83e3c44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:e83e64e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:e83e8f8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:e83eb836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04070 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Enzyme (Vitamin K-dependent protein C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:e83ee0e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:e83f0958-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:e83f3252-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e83f629a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e83f629a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e83f629a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e83fa1a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:e83fcae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28731 biolink:molecularly_interacts_with DrugCentral:776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabigatran etexilate targets Unclassified (Thrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:e83ff386-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.243']} DrugCentral uuid:e8401c1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:e84044c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.163']} DrugCentral uuid:e84070b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.087']} DrugCentral uuid:e8409958-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.248']} DrugCentral uuid:e840c20c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:e840ebce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.976']} DrugCentral uuid:e84114e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:e8413d90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.425']} DrugCentral uuid:e841664e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.708']} DrugCentral uuid:e8418fca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.894']} DrugCentral uuid:e841b888-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.462']} DrugCentral uuid:e841e132-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.265']} DrugCentral uuid:e84209dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:e842342a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.207']} DrugCentral uuid:e8425d06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.294']} DrugCentral uuid:e84285c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:e842aa2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:e842cee4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:e842f752-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets Enzyme (Steryl-sulfatase) DrugCentral uuid:e8431bce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e843446e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.053']} DrugCentral uuid:e8436d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:e84396b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 danazol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:e843bfd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:780 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dantrolene is antagonist of Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.757']} DrugCentral uuid:e843e892-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15413 biolink:molecularly_interacts_with DrugCentral:780 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dantrolene is antagonist of Ion channel (Ryanodine receptor 3) DrugCentral uuid:e8440e3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:780 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dantrolene targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:e84436e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.929']} DrugCentral uuid:e8445f66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.762']} DrugCentral uuid:e8448928-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:e844b236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.485']} DrugCentral uuid:e844dafe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole is antagonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e844ff66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.279']} DrugCentral uuid:e845282e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.388']} DrugCentral uuid:e845518c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:e8457608-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:e8459ea8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e845c734-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:e845f240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapsone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:e8461aea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapsone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:e8464394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C0X1 biolink:molecularly_interacts_with DrugCentral:782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapsone is inhibitor of Enzyme (Dihydropteroate synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:e8466c8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapsone targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:e8469506-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapsone targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:e846bd92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapsone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:e846e326-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4Z710 biolink:molecularly_interacts_with DrugCentral:782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapsone targets Unclassified (Dihydropteroate synthetase, putative) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:e8470cde-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0A113T0T6 biolink:molecularly_interacts_with DrugCentral:782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapsone targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:e84735ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapsone targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:e8475e8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q57P83 biolink:molecularly_interacts_with DrugCentral:783 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daptomycin targets Transporter (Outer membrane porin protein OmpD) DrugCentral uuid:e8478308-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darifenacin targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e847ace8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darifenacin targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e847d880-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darifenacin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e8480102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e84829a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e84852ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:e8487b46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e848a4f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:e848cd94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e848f6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:e8491f88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:e8494846-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:e84970dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.6']} DrugCentral uuid:e8499c38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:e849c55a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e849ee0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:e84a16ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Breakpoint cluster region protein) DrugCentral uuid:e84a3b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:e84a642e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:e84a8d64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:e84ab6b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e84adf6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.07']} DrugCentral uuid:e84b0802-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:e84b30b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e84b5abe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e84b83f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:e84bac8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e84bd52a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e84bfdfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:e84c2688-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.33']} DrugCentral uuid:e84c4eec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e84c7778-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:e84ca1da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.46']} DrugCentral uuid:e84cca8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:e84cf43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:e84d1cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:e84d47ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e84d7074-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e84d9928-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:e84dc236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:e84deb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:e84e1416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:e84e3cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e84e65ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:e84e8e8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:e84eb72c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e84edfae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.77']} DrugCentral uuid:e84f0a56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e84f3332-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:e84f5be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:e84f8486-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e84fad9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:e84fd620-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e84ffec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:e8502756-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e8505122-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e850799a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e850a334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.03']} DrugCentral uuid:e850cc7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:e850f55a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.51']} DrugCentral uuid:e8511df0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:e851469a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:e8517016-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.59']} DrugCentral uuid:e85198d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:e851c174-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.35']} DrugCentral uuid:e851ea1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:e8521354-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.25']} DrugCentral uuid:e8523bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:e852649e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.16']} DrugCentral uuid:e8528d3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.47']} DrugCentral uuid:e852b82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e852e338-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:e8530d0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:e85335cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e8535ed0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:e853877a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e853b010-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e853d928-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:e85401c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06240 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase LCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.19']} DrugCentral uuid:e8542a5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:e85452f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e8547ce8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.41']} DrugCentral uuid:e854a9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:e854d314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:e854fba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e8552486-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e8554d26-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e85575da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:e8559e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.68']} DrugCentral uuid:e855c7ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:e855f046-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e85618e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:e8564168-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e8566c60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:e85694ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27037 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Activin receptor type-2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e856bda0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:e856e67c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e8570fb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e8573866-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e85760fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:e8578a64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e857b318-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:e857db9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99640 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e8580430-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:e8582e10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e858569c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:e8587f1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36894 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Bone morphogenetic protein receptor type-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e858a8a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:e858d1b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5VT25 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e858fa52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:e8592414-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:e8594cbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e859761c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:e8599eb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e859c748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:e859effc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.16']} DrugCentral uuid:e85a1978-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:e85a422c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e85a6ac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:e85a939e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16277 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e85abc34-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.41']} DrugCentral uuid:e85ae4ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:e85b0d42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e85b3664-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:e85b5ef0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:e85b8772-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e85bb094-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:e85bdb6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e85c0742-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e85c3032-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:e85c58c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e85c81a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e85cab2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e85cd3de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:e85cfc6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e85d25b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e85d4e68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e85d76f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:e85da0ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:e85dcc1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:e85e0056-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e85e0056-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e85e0056-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e85e0056-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e85e4f0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase; MEK1/2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e85e4f0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase; MEK1/2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e85e86c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e85e86c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e85ebbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01538 biolink:molecularly_interacts_with DrugCentral:785 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasatinib targets Transcription factor (Myelin transcription factor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e85ee4ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e85f09d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:e85f2e40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:e85f5320-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicin targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:e85f7878-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:e85f9ce0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e85fc558-ac81-11ec-8b6b-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicin targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:e85fedbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deanol targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:e8601878-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28570 biolink:molecularly_interacts_with DrugCentral:787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deanol targets Transporter (Creatine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:e8604208-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:788 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 debrisoquine targets Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:e860665c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:788 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 debrisoquine targets Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:e8608ae2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:e860b3e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:e860dc68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:e86104e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e8613168-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e8613168-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e8617736-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:e8617736-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:e8617736-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:e8617736-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:e8617736-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:e861c312-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:790 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decitabine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e861ec52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:790 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 decitabine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:e86210ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:792 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deferoxamine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:e8623964-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:792 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deferoxamine targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e86261f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prasterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e8628b08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prasterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.84']} DrugCentral uuid:e862b3bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prasterone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e862dcca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GRG7 biolink:molecularly_interacts_with DrugCentral:795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prasterone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e863056a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:798 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.921']} DrugCentral uuid:e8632f86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:798 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.97']} DrugCentral uuid:e8635812-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delavirdine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.276']} DrugCentral uuid:e86380c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delavirdine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:e863a916-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delavirdine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e863d288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delavirdine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e863fc18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delavirdine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e86425bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delavirdine targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8645712-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:e8645712-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:e8645712-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e864cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:e865a57c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 demecarium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:e865c9da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 demeclocycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:e865ee42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 demeclocycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:e86612dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 demeclocycline targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e8663cb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 denopamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:e866655c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 denopamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e8668e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deptropine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e866b6c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WSF8 biolink:molecularly_interacts_with DrugCentral:808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deptropine targets Unclassified (Soluble acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:e866e86a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e866e86a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e866e86a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e8672794-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deserpidine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:e8674c42-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:e86771d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:e8679670-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:e867baf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:e867df72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:e8680970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:e8680970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e868718a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:e869320a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:e8695b40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.631']} DrugCentral uuid:e86983c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:e869ac3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:e869d548-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.755']} DrugCentral uuid:e869fdf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.081']} DrugCentral uuid:e86a266a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.194']} DrugCentral uuid:e86a4f00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:e86a78f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e86aa400-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e86acc78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e86af50e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:e86b1a16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:e86b42ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:e86b6b4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:e86b9504-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e86bbe12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e86be6a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:e86c0f2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:e86c3810-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:e86c643e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:e86c88b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:e86cb128-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.6']} DrugCentral uuid:e86cd9a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:e86d03f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e86d2cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:e86d5542-ac81-11ec-8b6b-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e86d7e50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e86da6d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e86dcf54-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86e2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e86eee84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e86eee84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e86eee84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e86f2d86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e86f56bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48545 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e86f8024-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e86fc412-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e86fc412-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e86fc412-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e86fc412-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e86fc412-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e86fc412-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e86fc412-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e86fc412-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:e87035a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:e8705e22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:e87086c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.956']} DrugCentral uuid:e870afda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.025']} DrugCentral uuid:e870d8e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:e8710188-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:e8712aa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:e871534a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.009']} DrugCentral uuid:e8717bea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.189']} DrugCentral uuid:e871a480-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:e871cea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.967']} DrugCentral uuid:e871f7d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e872204a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:e87248cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e8727234-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:e8729aac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e872c342-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e872ebba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.511']} DrugCentral uuid:e87315a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desloratadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:e8733e44-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75899 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets GPCR (Gamma-aminobutyric acid type B receptor subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.027']} DrugCentral uuid:e87366bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28476 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-2) DrugCentral uuid:e87392f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:e87392f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:e87392f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e8740a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e874d3b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desmopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e874fc48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desmopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:e87524f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desmopressin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e8754d7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desmopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:e87577c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desmopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e875a04e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desmopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:e875c902-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desmopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:e875f1c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desmopressin is agonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e8761ace-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desogestrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:e8763f36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desogestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:e87667d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:819 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoximetasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.932']} DrugCentral uuid:e8769076-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:819 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoximetasone targets Cytosolic other (Annexin A1) DrugCentral uuid:e876b59c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:819 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoximetasone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:e876de1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:e87706be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.498']} DrugCentral uuid:e8772f5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e87758da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoxycortone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e877818e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoxycortone is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11']} DrugCentral uuid:e877aa1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoxycortone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:e877d2c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoxycortone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:e8785fe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoxycorticosterone acetate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) DrugCentral uuid:e8788980-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:822 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desoxycorticosterone pivalate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:e878b28e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.886']} DrugCentral uuid:e878db42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.88']} DrugCentral uuid:e87903c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Cytosolic other (Annexin A1) DrugCentral uuid:e879291c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:e8795194-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e87979e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05112 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Cytokine (Interleukin-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:e879a306-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e879cc14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:e879f61c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.786']} DrugCentral uuid:e87a1eda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:e87a4766-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.517']} DrugCentral uuid:e87a7100-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:e87a9978-ac81-11ec-8b6b-0242ac110002 UniProtKB:O54915 biolink:molecularly_interacts_with DrugCentral:824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e87ac31c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:826 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:e87ae798-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:e87b133a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:e87b3bbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e87b6448-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:e87b8d2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone palmitate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:e87bb5b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone palmitate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:e87bde3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone palmitate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:e87c06b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone palmitate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:e87c2fe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:e87c584e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:e87c80c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e87ca93e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:e87cd328-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone valerate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:e87cfb96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone valerate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:e87d2404-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone valerate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:e87d4c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone valerate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:e87d753a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexbrompheniramine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:e87d99ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexetimide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:e87dc33c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexetimide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:e87dfc1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:e87dfc1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:e87dfc1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:e87dfc1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:e87dfc1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:e87e51c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:e87e7a52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:e87ea4fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:e87ed0a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:e87efa04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:e87f229a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.607']} DrugCentral uuid:e87f4b94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.384']} DrugCentral uuid:e87f7420-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:e87f9cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.042']} DrugCentral uuid:e87fc52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.257']} DrugCentral uuid:e87fee78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:e880183a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:e88040d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.733']} DrugCentral uuid:e8806a24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.577']} DrugCentral uuid:e88092a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.326']} DrugCentral uuid:e880bb0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.156']} DrugCentral uuid:e880e396-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e8810c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.898']} DrugCentral uuid:e881358a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.706']} DrugCentral uuid:e8815ee8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:e881876a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e881b0c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:833 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:e881d95e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:833 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:e88201b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:834 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexloxiglumide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:e8822a44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e8825500-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e8827dc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:e882a668-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e882cefe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:e882f7f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e8832084-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:e8834942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:e8837a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:e8837a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:e8837a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:e883c12e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e883c12e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e883c12e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e8840076-ac81-11ec-8b6b-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmedetomidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:e88429ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmethylphenidate is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:e8844e3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmethylphenidate is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e88476e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmethylphenidate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:e8849f68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmethylphenidate targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:e884d7d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:e884d7d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:e884d7d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:e884d7d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:e884d7d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:e8852faa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e88558ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:e885819e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:e885aa20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:e885d2ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:e885fcf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e8862586-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:e8864e1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e88676b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.824']} DrugCentral uuid:e8869fb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:e886c856-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e886f0d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:e887196e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:e8874330-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:e8876bbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:e8879bfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e8879bfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e8879bfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e887dffc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e887dffc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexniguldipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e8880e14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:e888327c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e8885c66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e88884f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:e888ad92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e888d20e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:e888fb44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:e8891fb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:e889484c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:e8896cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.87']} DrugCentral uuid:e8899612-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:e889be9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:e889e702-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:e88a0fac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e88a387e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e88a6100-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88abb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e88b7ae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan is agonist of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'D2', 'has_quantitative_value': ['6.458']} DrugCentral uuid:e88ba34e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.842']} DrugCentral uuid:e88bcbc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ks', 'has_quantitative_value': ['4.48']} DrugCentral uuid:e88bf45c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e88c1d4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan is blocker of Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:e88c45ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e88c6e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:e88c96d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e88cd728-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:e88cd728-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:e88cd728-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:e88cd728-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:e88cd728-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:e88cd728-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:e88cd728-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:e88d4ba4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e88d4ba4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e88d4ba4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e88d8ae2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:e88db440-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextromethorphan targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:e88ddd08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:844 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextropropoxyphene targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e88e015c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:844 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextropropoxyphene is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:e88e25c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:844 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextropropoxyphene targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:e88e4f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextrothyroxine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:e88e7d6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextrothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor) DrugCentral uuid:e88e7d6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextrothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor) DrugCentral uuid:e88ec2ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e88ec2ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e88ec2ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e88ec2ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e88ec2ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e88ec2ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e88ec2ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e88f3194-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:847 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dezocine is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e88f5a34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:847 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dezocine is antagonist of GPCR (Kappa-type opioid receptor) DrugCentral uuid:e88f7ea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42574 biolink:molecularly_interacts_with DrugCentral:849 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diacerein targets Enzyme (Caspase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e88fa732-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55210 biolink:molecularly_interacts_with DrugCentral:849 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diacerein targets Enzyme (Caspase-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:e88fcffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q17339 biolink:molecularly_interacts_with DrugCentral:849 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diacerein targets Unclassified (Female germline-specific tumor suppressor gld-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e88ff87c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02083 biolink:molecularly_interacts_with DrugCentral:849 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diacerein targets Enzyme (N-acylethanolamine-hydrolyzing acid amidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:e89028d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:e89028d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:e89028d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:e89068a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:e8909124-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:e890b99c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is allosteric modulator of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:e890e2d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e8910c12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:e8913502-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e8915ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:e891884a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:e891b0e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e891d96c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.67']} DrugCentral uuid:e8920202-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e8922b38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:e89253ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e8927c64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e892a4fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19969 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:e892d7e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:e892d7e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:e892d7e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:e8931ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:e8931ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:e8931ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:e8936804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:e8936804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:e8936804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:e893af26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:e893af26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:e893af26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:e893f6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:e893f6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:e893f6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:e8943f04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:e8943f04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:e8943f04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e894b8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e8959e44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e8959e44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e8959e44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e8959e44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e8959e44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e8959e44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e89608c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:e89608c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:e89608c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:e89650fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:e89650fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:e89650fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:e8969d30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e8969d30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e8969d30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8971288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e897e2d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e897e2d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e897e2d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e89829de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e89829de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e89829de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e8987628-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:e8987628-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:e8987628-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:e898bd2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:e898bd2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:e898bd2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:e8990476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:e8990476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:e8990476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:e8994bf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:e8994bf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:e8994bf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:e8998ce8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:854 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazoxide targets Enzyme (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.64']} DrugCentral uuid:e899b97a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:854 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazoxide is opener of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:e899b97a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:854 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazoxide is opener of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:e899ed6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:854 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diazoxide is activator of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:e89a1726-ac81-11ec-8b6b-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dibekacin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.921']} DrugCentral uuid:e89a40a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinchocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e89a651e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinchocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:e89a916a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e89a916a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e89a916a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e89ad102-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e89af9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazone is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.081']} DrugCentral uuid:e89b2256-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15118 biolink:molecularly_interacts_with DrugCentral:862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3']} DrugCentral uuid:e89b4b8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15119 biolink:molecularly_interacts_with DrugCentral:862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.699']} DrugCentral uuid:e89b73fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15120 biolink:molecularly_interacts_with DrugCentral:862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.097']} DrugCentral uuid:e89b9d9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16654 biolink:molecularly_interacts_with DrugCentral:862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.301']} DrugCentral uuid:e89bc634-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorophen targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:e89bf0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorophen targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:e89c1b8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorophen targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e89c441a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e89c6cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:e89c95dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e89cbe68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:e89ce6ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:e89d0f8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:e89d38d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:e89d616a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:e89d89e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.577']} DrugCentral uuid:e89db2fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.423']} DrugCentral uuid:e89ddcd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e89e0566-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e89e2e10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:e89e5700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:e89e7f96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:e89ea840-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:e89ed14e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e89efbb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:e89f2450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e89f4d0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:e89f75a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:e89f9fac-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e89fc84c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e89ff0e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e8a01964-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:e8a04286-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:e8a06b1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e8a093a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e8a0bc34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:e8a0e560-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dichlorphenamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:e8a10df6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e8a13682-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:e8a1601c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:e8a18bd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:e8a1b760-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac is antagonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e8a1e0f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e8a209e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8a23262-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:e8a25ada-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:e8a28366-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:e8a2ac88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e8a2d4ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e8a2fd82-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e8a3260e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e8a350e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:e8a37960-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:e8a3a200-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAW7 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:e8a3caa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19224 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:e8a3f3c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60656 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e8a41cb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAW8 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:e8a445de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:e8a46f14-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diclofenac targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:e8a4978c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e8a4c00e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e8a4e890-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:e8a513b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e8a53df4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e8a56252-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:e8a58aca-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:e8a5b3a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:e8a5dcfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e8a614a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e8a614a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e8a614a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e8a614a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e8a614a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:e8a66120-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.971']} DrugCentral uuid:e8a68970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15559 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol targets Enzyme (NAD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e8a6b206-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.388']} DrugCentral uuid:e8a6db14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.354']} DrugCentral uuid:e8a70706-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16549 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol targets Enzyme (Proprotein convertase subtilisin/kexin type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e8a73050-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:e8a75904-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:e8a781a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07374 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol targets Enzyme (Urease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e8a7aa1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WMN1 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol targets Enzyme (ATP phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e8a7d294-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05982 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol targets Enzyme (NULLD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e8a7fb34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicoumarol is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.509']} DrugCentral uuid:e8a8246a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.686']} DrugCentral uuid:e8a84cf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.773']} DrugCentral uuid:e8a87596-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:e8a89e36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.082']} DrugCentral uuid:e8a8c92e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:e8a8f412-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:e8a91c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.386']} DrugCentral uuid:e8a94520-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:e8a96e2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.079']} DrugCentral uuid:e8a997a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:e8a9c054-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.033']} DrugCentral uuid:e8a9e9a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.386']} DrugCentral uuid:e8aa1248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.767']} DrugCentral uuid:e8aa3b56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.327']} DrugCentral uuid:e8aa63ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70676 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets Unclassified (SMR1-alpha2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:e8aa8eee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:e8aabab8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.61']} DrugCentral uuid:e8aaec40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:e8aaec40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:e8aaec40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:e8ab2b88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72549 biolink:molecularly_interacts_with DrugCentral:869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 didanosine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e8ab548c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dienestrol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:e8ab7d2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:871 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dienogest is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:e8aba1bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:e8abcad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylcarbamazine targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:e8abef28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylcarbamazine targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:e8ac1778-ac81-11ec-8b6b-0242ac110002 UniProtKB:E1G1C3 biolink:molecularly_interacts_with DrugCentral:873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylcarbamazine is positive modulator of Ion channel (Nematode GABA-A receptor) DrugCentral uuid:e8ac1778-ac81-11ec-8b6b-0242ac110002 UniProtKB:E1G1C3 biolink:molecularly_interacts_with DrugCentral:873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylcarbamazine is positive modulator of Ion channel (Nematode GABA-A receptor) DrugCentral uuid:e8ac45cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:874 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylpropion is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:e8ac6c64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:874 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylpropion is inhibitor of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:e8ac9220-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.316']} DrugCentral uuid:e8acbaa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.894']} DrugCentral uuid:e8ace34c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.252']} DrugCentral uuid:e8ad0c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:e8ad34fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:e8ad5e94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:e8ad872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:e8adb06a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.276']} DrugCentral uuid:e8add90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.178']} DrugCentral uuid:e8ae0196-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.439']} DrugCentral uuid:e8ae2a2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:e8ae5470-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e8ae7d06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.575']} DrugCentral uuid:e8aea59c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.223']} DrugCentral uuid:e8aece8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.272']} DrugCentral uuid:e8aef718-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:e8af1fc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.437']} DrugCentral uuid:e8af4844-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.408']} DrugCentral uuid:e8af71fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.317']} DrugCentral uuid:e8af9aa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.657']} DrugCentral uuid:e8afc346-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:e8afebd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.778']} DrugCentral uuid:e8b0172e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:e8b03fd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:e8b0685a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.274']} DrugCentral uuid:e8b0910e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.739']} DrugCentral uuid:e8b0ba30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:e8b0e2da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.019']} DrugCentral uuid:e8b10b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.593']} DrugCentral uuid:e8b13406-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:e8b15e4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Estrogen-related receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e8b186c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e8b1af4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.983']} DrugCentral uuid:e8b1d8c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.847']} DrugCentral uuid:e8b201a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.361']} DrugCentral uuid:e8b22a28-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95718 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Steroid hormone receptor ERR2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e8b252b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.483']} DrugCentral uuid:e8b27b86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:e8b2a430-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e8b2ccb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.528']} DrugCentral uuid:e8b2f534-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.052']} DrugCentral uuid:e8b31e56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.214']} DrugCentral uuid:e8b346ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:e8b36f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:e8b39804-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08580 biolink:molecularly_interacts_with DrugCentral:875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e8b3c1f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 difenoxin is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:e8b3e66a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:880 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diflunisal is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:e8b40f0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:880 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diflunisal is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e8b437b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:880 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diflunisal targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e8b460ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:880 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diflunisal targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd1', 'has_quantitative_value': ['7.125']} DrugCentral uuid:e8b48930-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:880 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diflunisal targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:e8b4b1c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:880 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diflunisal is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:e8b4da66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:880 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diflunisal is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:e8b503b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.648']} DrugCentral uuid:e8b52c32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.857']} DrugCentral uuid:e8b556a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:e8b57b2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50997 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8b5a766-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:e8b5eb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8b5eb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8b5eb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8b5eb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8b5eb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8b5eb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8b5eb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8b5eb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8b66516-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.783']} DrugCentral uuid:e8b68d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.136']} DrugCentral uuid:e8b6b624-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e8b6df5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50997 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e8b707d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:e8b74b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8b74b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8b74b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8b74b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8b74b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8b74b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8b74b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8b74b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8b7c924-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51450 biolink:molecularly_interacts_with DrugCentral:882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 digoxin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e8b7f1ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.007']} DrugCentral uuid:e8b81a6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:e8b84318-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.187']} DrugCentral uuid:e8b86bae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.526']} DrugCentral uuid:e8b894f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:e8b8bd8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:e8b8e638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:e8b90ece-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.085']} DrugCentral uuid:e8b9391c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.114']} DrugCentral uuid:e8b96414-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.121']} DrugCentral uuid:e8b98cb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:e8b9b554-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:e8b9de4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.728']} DrugCentral uuid:e8ba06d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.261']} DrugCentral uuid:e8ba2f70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.369']} DrugCentral uuid:e8ba57f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:e8ba810a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e8baaad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.299']} DrugCentral uuid:e8bad3e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e8bafc66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:e8bb27c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:886 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydrocodeine is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:e8bb4c02-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.087']} DrugCentral uuid:e8bb7498-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.462']} DrugCentral uuid:e8bb9d88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:e8bbc70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.309']} DrugCentral uuid:e8bbefb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.127']} DrugCentral uuid:e8bc184e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:e8bc43aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.385']} DrugCentral uuid:e8bc719a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.373']} DrugCentral uuid:e8bc9a26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.377']} DrugCentral uuid:e8bcc2b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.903']} DrugCentral uuid:e8bcedbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:e8bd197e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e8bd3fee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.442']} DrugCentral uuid:e8bd6884-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:e8bd91a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.605']} DrugCentral uuid:e8bdba46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1D) DrugCentral uuid:e8bddea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:e8be0758-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.183']} DrugCentral uuid:e8be30a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:e8be5514-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:e8be7daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:e8bea640-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.896']} DrugCentral uuid:e8becff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:e8bef87a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.79']} DrugCentral uuid:e8bf20e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.14']} DrugCentral uuid:e8bf49c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocristine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e8bf723c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.804']} DrugCentral uuid:e8bf9ad2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.922']} DrugCentral uuid:e8bfc35e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.529']} DrugCentral uuid:e8bfed7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.412']} DrugCentral uuid:e8c01606-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:e8c03e9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.424']} DrugCentral uuid:e8c06854-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.644']} DrugCentral uuid:e8c0923e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.364']} DrugCentral uuid:e8c0bb74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:e8c0e400-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.83']} DrugCentral uuid:e8c10ca0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e8c135ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e8c15a16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.752']} DrugCentral uuid:e8c182c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.742']} DrugCentral uuid:e8c1ab56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:e8c1d4b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:e8c1fd54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.821']} DrugCentral uuid:e8c225d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.69']} DrugCentral uuid:e8c24e62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:e8c2755e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 5A) DrugCentral uuid:e8c299bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e8c2c252-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e8c2eae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.349']} DrugCentral uuid:e8c313e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.416']} DrugCentral uuid:e8c33c5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e8c364d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.18']} DrugCentral uuid:e8c38df4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e8c3b68a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:e8c3deee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e8c40856-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e8c43240-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:e8c45afe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:e8c48b32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:e8c48b32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:e8c48b32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:e8c4cad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:889 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinidine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e8c4ef28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:889 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:e8c5137c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:889 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:e8c537c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:889 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:e8c55c10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:889 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:e8c58118-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:889 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:e8c5a576-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dilazep targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e8c5d5be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e8c5d5be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e8c5d5be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e8c61916-ac81-11ec-8b6b-0242ac110002 UniProtKB:O54699 biolink:molecularly_interacts_with DrugCentral:893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dilazep targets Transporter (Equilibrative nucleoside transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:e8c641d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:894 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dilevalol targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:e8c66646-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:894 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dilevalol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:e8c68a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:894 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dilevalol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e8c6af52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:894 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dilevalol targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:e8c6d3b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:894 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dilevalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:e8c6fc3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:e8c724b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.736']} DrugCentral uuid:e8c74dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:e8c776e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e8c79f84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:e8c7c8ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e8c7f4b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:e8c81d42-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.017']} DrugCentral uuid:e8c845f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:e8c86f04-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:e8c8977c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:e8c8c01c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:e8c8e8a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:e8c911d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:e8c94230-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:e8c94230-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:e8c94230-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:e8c988c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e8c988c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e8c988c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e8c9cbec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e8c9f7b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:e8ca2308-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JIS7 biolink:molecularly_interacts_with DrugCentral:897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diltiazem is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e8ca4c0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:900 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimemorfan is inhibitor of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:e8ca74a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.791']} DrugCentral uuid:e8ca9d24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.312']} DrugCentral uuid:e8cac646-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.695']} DrugCentral uuid:e8caef86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.703']} DrugCentral uuid:e8cb1826-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e8cb41b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.479']} DrugCentral uuid:e8cb6ba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:e8cb9526-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:e8cbbdee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:e8cbe67a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.785']} DrugCentral uuid:e8cc0f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:e8cc380a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:e8cc6096-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.644']} DrugCentral uuid:e8cc892c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.749']} DrugCentral uuid:e8ccb23a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.821']} DrugCentral uuid:e8ccdac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimenhydrinate targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:e8cd0352-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7KQK5 biolink:molecularly_interacts_with DrugCentral:902 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimetacrine targets Unclassified (Apical membrane antigen 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:e8cd2bb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimetindene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:e8cd560e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:e8cd8192-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:e8cdaa46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:e8cdd2e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e8cdfbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e8ce2c32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:e8ce2c32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:e8ce2c32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:e8ce6f3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:908 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimethyltubocurarinium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:e8ce6f3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:908 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimethyltubocurarinium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:e8ce9df2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:911 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dioxyline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:e8cec660-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:911 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dioxyline targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:e8ceefc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:e8cf184a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8cf43ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:e8cf6c5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e8cf94f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e8cfbd86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:e8cfe662-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e8d00ef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e8d0378e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e8d060d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:e8d0896e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:e8d0b1fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43117 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:e8d0da68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e8d104e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e8d12d74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e8d1561e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:e8d17e8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8d1a79a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:e8d1d030-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e8d1f8e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:e8d22166-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:e8d24a88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:e8d27332-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e8d29bc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:e8d2c44a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e8d2f136-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e8d31d1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:e8d3460e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:e8d36f12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e8d397a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:e8d3c03e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e8d3e8ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:e8d41282-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43117 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e8d43b22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:e8d46390-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:e8d48c30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e8d4b6b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e8d4e0ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e8d50958-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e8d531da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:e8d55ade-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:e8d5834c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:913 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e8d5abec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:915 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphemanil is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:e8d5d05e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:915 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphemanil is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:e8d5f57a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:e8d61de8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.018']} DrugCentral uuid:e8d64660-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:e8d66f0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:e8d69ab6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:e8d6c360-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.81']} DrugCentral uuid:e8d6ecc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:e8d716d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e8d73f70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:e8d76810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e8d79074-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:e8d7b9aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.585']} DrugCentral uuid:e8d7e22c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.932']} DrugCentral uuid:e8d80ad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e8d83358-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.678']} DrugCentral uuid:e8d8663e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e8d8663e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e8d8663e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e8d8a5c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:e8d8ce44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenhydramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.658']} DrugCentral uuid:e8d8f748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:918 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenoxylate is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.167']} DrugCentral uuid:e8d91fd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:918 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenoxylate targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e8d94856-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenylpyraline is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.076']} DrugCentral uuid:e8d970ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenylpyraline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:e8d99a18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenylpyraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.377']} DrugCentral uuid:e8d9c27c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenylpyraline targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:e8d9e6e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diphenylpyraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:e8da0f66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipivefrine is agonist of GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:e8da3518-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipivefrine is agonist of GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:e8da5a02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipivefrine is agonist of GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:e8da80ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:923 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diprafenone targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:e8daa516-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:923 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diprafenone targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e8dacaaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:923 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diprafenone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:e8daef30-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:e8db17da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:e8db4066-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8db69e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e8db92a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.802']} DrugCentral uuid:e8dbbb2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:e8dbe3f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e8dc0d3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e8dc35c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 7B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e8dc5e6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60658 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e8dc86ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.158']} DrugCentral uuid:e8dcb0f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:e8dcd980-ac81-11ec-8b6b-0242ac110002 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:e8dd05fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:e8dd05fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:e8dd3e70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e8dd3e70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e8dd85ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e8dd85ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e8dd85ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e8dd85ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e8dd85ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e8dd85ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e8ddf3b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:e8ddf3b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:e8ddf3b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:e8de3334-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:e8de5bc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86TP1 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole targets Enzyme (Protein prune homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e8de849c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e8dead0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DTD1 biolink:molecularly_interacts_with DrugCentral:924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dipyridamole is inhibitor of Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:e8ded58c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:926 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disopyramide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e8defa12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:926 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disopyramide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.036']} DrugCentral uuid:e8df2334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:926 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disopyramide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:e8df4bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:926 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:e8df7014-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:926 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:e8df9472-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:926 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:e8dfbbd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48544 biolink:molecularly_interacts_with DrugCentral:926 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disopyramide targets Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:e8dfe56c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:926 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disopyramide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:e8e00dee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:926 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disopyramide targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.604']} DrugCentral uuid:e8e0372e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 distigmine is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:e8e05c04-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:e8e0849a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.846']} DrugCentral uuid:e8e0ad30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Transporter (Translocator protein) DrugCentral uuid:e8e0d18e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.967']} DrugCentral uuid:e8e0face-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.115']} DrugCentral uuid:e8e12364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.735']} DrugCentral uuid:e8e14bfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.156']} DrugCentral uuid:e8e17580-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.658']} DrugCentral uuid:e8e19f56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.129']} DrugCentral uuid:e8e1c8fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.833']} DrugCentral uuid:e8e1f19a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.434']} DrugCentral uuid:e8e21a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.434']} DrugCentral uuid:e8e24316-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:e8e26bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.957']} DrugCentral uuid:e8e29474-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:e8e2bdb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:e8e2e636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.862']} DrugCentral uuid:e8e30ecc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05091 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram is inhibitor of Enzyme (Aldehyde dehydrogenase, mitochondrial) DrugCentral uuid:e8e3332a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.319']} DrugCentral uuid:e8e35df0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.738']} DrugCentral uuid:e8e389b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25025 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (C-X-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:e8e3b28c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:e8e3db18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.821']} DrugCentral uuid:e8e403f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.794']} DrugCentral uuid:e8e42c76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.669']} DrugCentral uuid:e8e45516-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.357']} DrugCentral uuid:e8e47db6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.333']} DrugCentral uuid:e8e4a6f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11884 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Aldehyde dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e8e4cf64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99685 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:e8e4f7dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:e8e5216c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e8e54d2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29375 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Lysine-specific demethylase 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e8e57658-ac81-11ec-8b6b-0242ac110002 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:e8e59eee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:e8e5c87e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e8e5f204-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e8e61aa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:e8e64344-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57764 biolink:molecularly_interacts_with DrugCentral:928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disulfiram targets Unclassified (Gasdermin-D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8e66c66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9VTU8 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 2, isoform A; LD26647p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:e8e69510-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9V396 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 1; GH09688p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:e8e6bdba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:e8e6e66e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e8e711fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e8e73d80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e8e76652-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e8e78fe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05181 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Cytochrome P450 2E1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:e8e7b990-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:e8e7e24e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e8e80af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:e8e8341a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57764 biolink:molecularly_interacts_with DrugCentral:931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ditiocarb targets Unclassified (Gasdermin-D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e8e85cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:e8e8855a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R4D5 biolink:molecularly_interacts_with DrugCentral:934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e8e8add2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R455 biolink:molecularly_interacts_with DrugCentral:934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:e8e8d82a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomenthol is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:e8e900ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7Z2W7 biolink:molecularly_interacts_with DrugCentral:934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e8e92942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:e8e951c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e8e97aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.976']} DrugCentral uuid:e8e9a322-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:e8e9cba4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:e8e9f502-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:e8ea1ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.771']} DrugCentral uuid:e8ea4778-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:e8ea6ffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:e8ea9886-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:e8eac1f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e8eaea8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:e8eb132e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:e8eb3c28-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:e8eb64c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.256']} DrugCentral uuid:e8eb8d54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:e8ebb612-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e8ebdf3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e8ec07fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.258']} DrugCentral uuid:e8ec307e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.401']} DrugCentral uuid:e8ec5914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.301']} DrugCentral uuid:e8ec827c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:e8ecab26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:e8ecd3c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:e8ecfc70-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:e8ed254c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.223']} DrugCentral uuid:e8ed4dd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:e8ed765a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:e8ed9ee6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:e8edc92a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:e8edf2a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:e8ee1b64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e8ee4468-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e8ee6a7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:e8ee8efa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.086']} DrugCentral uuid:e8eeb786-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.283']} DrugCentral uuid:e8eee062-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel targets GPCR (Growth hormone-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:e8ef27c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e8ef27c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e8ef27c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e8ef27c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e8ef27c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e8ef27c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e8ef27c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e8ef27c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e8ef27c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e8efac04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docetaxel targets Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8efff6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:e8f0959c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dofetilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:e8f0be96-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dofetilide targets Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:e8f0e31c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dofetilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e8f10bbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.766']} DrugCentral uuid:e8f13484-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e8f15dce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.988']} DrugCentral uuid:e8f18678-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:e8f1af04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e8f1d48e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:e8f1ff0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.586']} DrugCentral uuid:e8f2283a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:e8f250f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:e8f279ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:e8f2a2a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:e8f2cb50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.013']} DrugCentral uuid:e8f2f3dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:e8f31c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:e8f345a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:e8f36e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:e8f396a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:e8f3bf2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:e8f3e918-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:e8f4119a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.553']} DrugCentral uuid:e8f441e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:e8f441e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:e8f441e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:e8f47ba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:e8f4a43e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:e8f4ccca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:e8f4f574-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:e8f51ec8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.93']} DrugCentral uuid:e8f54768-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e8f56fcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e8f59934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domperidone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:e8f5c508-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:e8f5f0dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e8f61c9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:e8f64730-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.046']} DrugCentral uuid:e8f67052-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e8f698f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e8f6c17e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:e8f6eac8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:e8f71340-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e8f73ba4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:e8f76430-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:e8f78d52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:e8f7b764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e8f7dff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e8f808ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:e8f8316c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32738 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Choline O-acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:e8f859e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e8f88374-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e8f8acbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:e8f8d55e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:e8f8fdea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:e8f92662-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e8f950a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.19']} DrugCentral uuid:e8f97b62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e8f9a3ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e8f9cc7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.18']} DrugCentral uuid:e8f9f542-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.084']} DrugCentral uuid:e8fa1de2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e8fa466e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e8fa6f04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e8fa9858-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e8fac0e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.375']} DrugCentral uuid:e8fae970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e8fb11fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e8fb3e48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:e8fb69fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e8fb958c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:e8fbc048-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e8fbe8d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:e8fc116a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:e8fc39f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e8fc6322-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:e8fc8ba4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:e8fcb4da-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e8fcddf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09172 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (Dopamine beta-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3']} DrugCentral uuid:e8fd1484-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e8fd1484-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e8fd1484-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e8fd1484-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e8fd6678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e8fd6678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e8fd6678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e8fdab74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:e8fdab74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:e8fdeec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e8fdeec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e8fdeec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e8fdeec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e8fdeec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e8fe4cf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e8fe4cf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e8fe4cf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e8fea70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e8fea70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e8fea70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e8fea70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e8fea70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e8fea70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e8fea70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e8fea70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e8ff2706-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:e8ff4fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e8ff7878-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8I2J3 biolink:molecularly_interacts_with DrugCentral:947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopamine targets Enzyme (M18 aspartyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e8ffa0d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:948 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopexamine targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:e8ffc530-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:948 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dopexamine targets GPCR (D(1A) dopamine receptor) DrugCentral uuid:e8ffe9b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:e900130a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e9003baa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:e9006454-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e9008d08-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:e900b94a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:e900e514-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:e9010daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:e90136ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e9015f44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e90187ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e901b098-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:e901daf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:e902039a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:e9022c30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e90254b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:e9027f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:e902aa34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e902d2d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:e902fb56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:e9032540-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:e9034dfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:e9037716-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:e9039fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:e903c8d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:e903f164-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:e90419fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:e90443bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e9046c5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e90494f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:e904bd88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:e904e682-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dorzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e9050f36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.066']} DrugCentral uuid:e90537ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.337']} DrugCentral uuid:e905606c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.588']} DrugCentral uuid:e90589ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.378']} DrugCentral uuid:e905b256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:e905dae2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e906036e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.744']} DrugCentral uuid:e9062e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:e9065698-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e9067f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:e906a7a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:e906d08c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dosulepin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.275']} DrugCentral uuid:e906f90e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:953 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxapram targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e907226c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:953 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxapram is blocker of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:e90746f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:953 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxapram is blocker of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:e9076be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:e9079490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:e907bd26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:e907e7c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:e90810b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e908394a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.845']} DrugCentral uuid:e90861ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.631']} DrugCentral uuid:e9088af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:e908b3a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:e908dc60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:e90904f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.827']} DrugCentral uuid:e9092e4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:e90956f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e909802a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e909a8a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.381']} DrugCentral uuid:e909d368-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.81']} DrugCentral uuid:e909fec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxazosin targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e90a2818-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e90a505e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e90a791c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e90aa19e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:e90aca16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:e90af2a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.53']} DrugCentral uuid:e90b1caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:e90b4554-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:e90b6dcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e90b97ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e90bc1e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:e90bea5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 7) DrugCentral uuid:e90c0ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.629']} DrugCentral uuid:e90c37b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e90c6056-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.325']} DrugCentral uuid:e90c8900-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:e90cb182-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:e90cda9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e90d031c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:e90d2bb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:e90d542a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:e90d7ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:e90da754-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e90dcfcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:e90df9d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:e90e22ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:e90e4b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11']} DrugCentral uuid:e90e73d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.886']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90ecf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e90f8f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxepin is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:e90fb7c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:957 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxercalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:e90fdca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxifluridine targets Enzyme (Thymidylate synthase) DrugCentral uuid:e9100116-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:e91029c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:e9105256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.433']} DrugCentral uuid:e9107b96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:e910a026-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e910c916-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:e910ed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:e91112c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:e9113752-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.914']} DrugCentral uuid:e9115fac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.496']} DrugCentral uuid:e9118838-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.288']} DrugCentral uuid:e911b11e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.605']} DrugCentral uuid:e911d98c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e912020e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e9122b76-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e912547a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e9127d06-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e912a6a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61823 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Enzyme (Ribonuclease pancreatic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e912cf4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.867']} DrugCentral uuid:e912f948-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.805']} DrugCentral uuid:e91321f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e9134a7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:e913730a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43870 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Unclassified (Type-2 restriction enzyme HindIII) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:e9139bfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O52691 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Unclassified (Type-2 restriction enzyme ScaI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e913c472-ac81-11ec-8b6b-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:e913ecb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WIQ1 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Enzyme (UDP-galactopyranose mutase) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e9141526-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxorubicin targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e9143e3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxycycline targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:e9146292-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxycycline targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:e9148af6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08254 biolink:molecularly_interacts_with DrugCentral:961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxycycline targets Enzyme (Stromelysin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e914b364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxycycline is inhibitor of Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e914dcc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45452 biolink:molecularly_interacts_with DrugCentral:961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxycycline is inhibitor of Enzyme (Collagenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e915054e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02980 biolink:molecularly_interacts_with DrugCentral:961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxycycline targets Transporter (Tetracycline resistance protein, class B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:e9152db2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxycycline targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:e915567a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09237 biolink:molecularly_interacts_with DrugCentral:961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxycycline is inhibitor of Enzyme (Matrilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.14']} DrugCentral uuid:e9157f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxylamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:e915a378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:965 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 drostanolone propionate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:e915c7d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.199']} DrugCentral uuid:e915f10c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:e91619c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.602']} DrugCentral uuid:e916436e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:e9166c04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:e91695d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:e916bf1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.132']} DrugCentral uuid:e916e7ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.069']} DrugCentral uuid:e9171050-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.623']} DrugCentral uuid:e9173954-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.996']} DrugCentral uuid:e91761ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.027']} DrugCentral uuid:e9178a9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:e917b32a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:e917dc6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.782']} DrugCentral uuid:e91804f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.592']} DrugCentral uuid:e9182d96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.076']} DrugCentral uuid:e918562c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.175']} DrugCentral uuid:e91880de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:e918aaaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.695']} DrugCentral uuid:e918d336-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.78']} DrugCentral uuid:e918fbb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:e9192c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:e9192c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:e9192c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:e9196bac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:968 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 drospirenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.5']} DrugCentral uuid:e9199424-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:968 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 drospirenone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:e919bd14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:968 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 drospirenone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.5']} DrugCentral uuid:e919e56e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:969 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 drotaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:e91a0aa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:969 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 drotaverine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:e91a2f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e91a78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:e91a78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:e91a78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:e91a78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:e91a78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:e91a78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:e91a78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:e91a78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:e91a78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:e91aec7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 droxidopa is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e91b152e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:e91b3dc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:e91b6646-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:e91b8f36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e91bb7e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:e91be06c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e91c090c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e91c3242-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:e91c5aba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:e91c8328-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.402']} DrugCentral uuid:e91cac5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:e91cd4ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:e91cfd62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.352']} DrugCentral uuid:e91d25da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.428']} DrugCentral uuid:e91d4f4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.09']} DrugCentral uuid:e91d78fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:e91da26c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e91dcb2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duloxetine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e91df582-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dutasteride targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e91e1e04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dutasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:e91e46a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18405 biolink:molecularly_interacts_with DrugCentral:973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dutasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:e91e6f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dyclonine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:e91e985c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dyclonine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:e91ebcce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:975 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dydrogesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e91ee578-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:975 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dydrogesterone targets Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.561']} DrugCentral uuid:e91f0e36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:976 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diprophylline is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) DrugCentral uuid:e91f332a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:976 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diprophylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:e91f5788-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:e91f8000-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e91fa88c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.506']} DrugCentral uuid:e91fd2f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:e91ffb8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:e9202410-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:e9204ca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:e92075fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:e9209e72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.588']} DrugCentral uuid:e920c6fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.701']} DrugCentral uuid:e920efee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.905']} DrugCentral uuid:e9211870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:e92140e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.472']} DrugCentral uuid:e921697e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.384']} DrugCentral uuid:e921935e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.543']} DrugCentral uuid:e921bd66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e921e5e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.554']} DrugCentral uuid:e9220e74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:e92237be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.937']} DrugCentral uuid:e9226054-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.615']} DrugCentral uuid:e92288d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.719']} DrugCentral uuid:e922b176-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.397']} DrugCentral uuid:e922daf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.106']} DrugCentral uuid:e923037e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.743']} DrugCentral uuid:e9232bf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:e923548c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:e9238088-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.126']} DrugCentral uuid:e923a914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.253']} DrugCentral uuid:e923d196-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:e923faae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.976']} DrugCentral uuid:e924233a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.191']} DrugCentral uuid:e9244bbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.633']} DrugCentral uuid:e9247452-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.849']} DrugCentral uuid:e9249d74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.871']} DrugCentral uuid:e924c5f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:e924ee5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:e92516c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e92540da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:979 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ebrotidine is antagonist of GPCR (Histamine H2 receptor) DrugCentral uuid:e9256556-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 echothiophate is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:e92589b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.131']} DrugCentral uuid:e925b240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.543']} DrugCentral uuid:e925dc20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.636']} DrugCentral uuid:e92604b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.336']} DrugCentral uuid:e9262d6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e92655ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.086']} DrugCentral uuid:e9267f18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:e926a7b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.052']} DrugCentral uuid:e926d058-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:e926f8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.648']} DrugCentral uuid:e92723a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.617']} DrugCentral uuid:e9274c22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.034']} DrugCentral uuid:e92774ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.939']} DrugCentral uuid:e9279d58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.362']} DrugCentral uuid:e927c670-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.202']} DrugCentral uuid:e927ef24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:e92817ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.572']} DrugCentral uuid:e9284122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.792']} DrugCentral uuid:e928699a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.805']} DrugCentral uuid:e92892a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.197']} DrugCentral uuid:e928bb3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.936']} DrugCentral uuid:e928e532-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.421']} DrugCentral uuid:e92910ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.529']} DrugCentral uuid:e9293cb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.336']} DrugCentral uuid:e929653e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.178']} DrugCentral uuid:e9298f5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:e929b7b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.006']} DrugCentral uuid:e929e144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:e92a09e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.485']} DrugCentral uuid:e92a332e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.359']} DrugCentral uuid:e92a5bce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.463']} DrugCentral uuid:e92a848c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:e92aa8fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.294']} DrugCentral uuid:e92ad52c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e92b00d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.864']} DrugCentral uuid:e92b29a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e92b525e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:e92b7ad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.489']} DrugCentral uuid:e92ba31c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.189']} DrugCentral uuid:e92bcbb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:e92bf4d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:e92c1d56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.916']} DrugCentral uuid:e92c45c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.857']} DrugCentral uuid:e92c6e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:e92c98ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e92cc4cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:e92cedc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:e92d1652-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:e92d3f42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:e92d67c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.999']} DrugCentral uuid:e92d9064-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.431']} DrugCentral uuid:e92db8fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.503']} DrugCentral uuid:e92de24e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49146 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Neuropeptide Y receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.959']} DrugCentral uuid:e92e0bde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.498']} DrugCentral uuid:e92e3488-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:e92e5e22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:e92e8a6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:e92eb642-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:e92ee20c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:e92f0c96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e92f352c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e92f5dae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:e92f864e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e92fb0ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:e92fd96e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e9300218-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 econazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:e9302ab8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:986 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edatrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:e93056dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:986 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edatrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:e9307b76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:986 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edatrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e930a434-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:986 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edatrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e930cd38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edetic acid targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e930f5ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edetic acid targets Enzyme (Ceramide glucosyltransferase) DrugCentral uuid:e9311a4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q79MP6 biolink:molecularly_interacts_with DrugCentral:987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edetic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:e93142c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XAY4 biolink:molecularly_interacts_with DrugCentral:987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edetic acid targets Unclassified (Beta-lactamase VIM-1; Class B carbapenemase VIM-1; Metallo-beta-lactamase; Metallo-beta-lactamase VIM-1; Metallobeta-lactamase; VIM-1; VIM-1 metallo-beta lactamase; VIM-1 metallo-beta-lactamase; VIM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e9316bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:J3SE37 biolink:molecularly_interacts_with DrugCentral:987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edetic acid targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:e931945c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edetic acid targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e931bce8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edetic acid targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:e931e574-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edetic acid targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:e93210c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:988 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edrophonium is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.79']} DrugCentral uuid:e9323cae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:988 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edrophonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e9326576-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efavirenz is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:e9328df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efavirenz targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:e932b2ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efavirenz is inhibitor of Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:e932db96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efavirenz is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e9330440-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efavirenz targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:e9332cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efavirenz is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:e933568e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efavirenz targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:e9337f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11926 biolink:molecularly_interacts_with DrugCentral:990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eflornithine is inhibitor of Enzyme (Ornithine decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e933a7ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09057 biolink:molecularly_interacts_with DrugCentral:990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eflornithine targets Enzyme (Ornithine decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:e933d064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9TZZ6 biolink:molecularly_interacts_with DrugCentral:990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eflornithine is inhibitor of Enzyme (Ornithine decarboxylase) DrugCentral uuid:e933f7d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O54898 biolink:molecularly_interacts_with DrugCentral:992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efonidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e93420a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efonidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.621']} DrugCentral uuid:e9344d0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efonidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e9344d0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efonidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:e9347bb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:995 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e934a462-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:995 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e934cd02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:995 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e934f5a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:995 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e9351ece-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:995 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e935475a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elliptinium targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e9356fdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elliptinium targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:e9359976-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elliptinium targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e935cbda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:e935cbda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:e935cbda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e93645d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:e9371904-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emedastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:e93741a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emetine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:e9376a4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emetine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:e93793de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emetine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.578']} DrugCentral uuid:e937bc74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emetine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:e937e500-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emetine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e9380d8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75884 biolink:molecularly_interacts_with DrugCentral:1001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emetine targets Enzyme (Putative hydrolase RBBP9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e938367c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1003 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emtricitabine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:e9385bf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1005 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enalapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e938847e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1005 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enalapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e938ad0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:1005 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enalapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:e938d668-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enalaprilat is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e938feea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:e9392794-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:1006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:e939502a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5EGZ1 biolink:molecularly_interacts_with DrugCentral:1006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e9397c4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09470 biolink:molecularly_interacts_with DrugCentral:1006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.94']} DrugCentral uuid:e939a552-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1007 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 encainide targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e939c9ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1007 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:e939ef76-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1007 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:e93a1442-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1007 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:e93a3936-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1007 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:e93a5d9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 endralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:e93a8238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1009 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enflurane is positive modulator of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:e93aa754-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1009 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:e93acbe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1009 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:e93af056-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1009 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:e93b14dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1009 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:e93b39ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1009 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:e93b5e42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q53I07 biolink:molecularly_interacts_with DrugCentral:1010 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfuvirtide targets Viral envelope protein (Envelope glycoprotein) DrugCentral uuid:e93b82aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O40239 biolink:molecularly_interacts_with DrugCentral:1010 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfuvirtide is inhibitor of Membrane other (Transmembrane glycoprotein gp41) DrugCentral uuid:e93ba708-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q76270 biolink:molecularly_interacts_with DrugCentral:1010 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfuvirtide targets Unclassified (GP41) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e93bcfc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43700 biolink:molecularly_interacts_with DrugCentral:1013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxacin targets Enzyme (DNA gyrase subunit A) DrugCentral uuid:e93bf438-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21281 biolink:molecularly_interacts_with DrugCentral:1013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxacin targets Enzyme (V-type proton ATPase subunit B, brain isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e93c208e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5EP76 biolink:molecularly_interacts_with DrugCentral:1013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:e93c208e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5EP76 biolink:molecularly_interacts_with DrugCentral:1013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:e93c52c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48371 biolink:molecularly_interacts_with DrugCentral:1013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:e93c52c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48371 biolink:molecularly_interacts_with DrugCentral:1013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:e93c81c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoximone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.345']} DrugCentral uuid:e93cb6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e93cb6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e93cb6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e93cb6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e93d026a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprofylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e93d2cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:e93d556c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:1015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprofylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:e93d7e16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprofylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.03']} DrugCentral uuid:e93da724-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:1015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprofylline targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:e93dcb8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e93df440-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprofylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e93e1ce0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprofylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:e93e462a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:1015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:e93e6ede-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:1015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprofylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:e93e977e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprostil targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e93ec000-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprostil targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:e93ee9d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprostil targets GPCR (Prostacyclin receptor) DrugCentral uuid:e93f0e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e93f380a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprostil is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e93f60b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:1016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:e93f89ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:1016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e93fb230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entacapone targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e93fdab2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entacapone targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:e940033e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:1018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entacapone targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e9402c6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:1018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entacapone targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e940558c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:1018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entacapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.523']} DrugCentral uuid:e9407ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17394 biolink:molecularly_interacts_with DrugCentral:1019 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entecavir targets Polyprotein (Protein P) DrugCentral uuid:e940a352-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:1019 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entecavir is inhibitor of Polyprotein (Protein P) DrugCentral uuid:e940ca4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:1019 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entecavir targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:e940f2b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:1021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:e9411b2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:1021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:e941438e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epalrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e9416c56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:1021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epalrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:e94194e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:1021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:e941bd6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epalrestat targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e941e6a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00796 biolink:molecularly_interacts_with DrugCentral:1021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epalrestat targets Enzyme (Sorbitol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:e9420f26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02928 biolink:molecularly_interacts_with DrugCentral:1021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epalrestat is inhibitor of Enzyme (Cytochrome P450 4A11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:e94237da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epalrestat is inhibitor of Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.678']} DrugCentral uuid:e942603e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eperisone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e9428a64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eperisone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.859']} DrugCentral uuid:e942b4e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eperisone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:e942dd7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eperisone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:e9430606-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1024 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ephedrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e9432ece-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:e9435336-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e9437bc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e9439fee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:e943c4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e943e940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:e9441230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine targets GPCR (Histamine H2 receptor) DrugCentral uuid:e9443666-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:e9446050-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e9448a9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e944b410-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinastine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:e944dc7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.401']} DrugCentral uuid:e94506a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e9452f44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.26']} DrugCentral uuid:e94557ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:e94580ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:e945a9f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.434']} DrugCentral uuid:e945d2aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e945fb5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.401']} DrugCentral uuid:e94624a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.449']} DrugCentral uuid:e9465130-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:e9467ce6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e946a766-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.484']} DrugCentral uuid:e946d024-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:e946f8ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e9472132-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e94749be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e9477312-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e9479bb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:e947c448-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10608 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:e947ece8-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e9481f6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e9481f6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e9481f6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e9486678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:e9486678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:e9486678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:e948a728-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8I2J3 biolink:molecularly_interacts_with DrugCentral:1028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epinephrine targets Enzyme (M18 aspartyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e948cfaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1030 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epirubicin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.878']} DrugCentral uuid:e948f84a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1030 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epirubicin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.286']} DrugCentral uuid:e94920cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:1030 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epirubicin targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:e94949f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eplerenone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:e949728e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eplerenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e9499b1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eplerenone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e949c3ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:1032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eplerenone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e949edfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eplerenone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e94a16b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eplerenone targets Nuclear other (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e94a3f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:1032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eplerenone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e94a67e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epoprostenol is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e94a90ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:1034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epoprostenol targets GPCR (P2Y purinoceptor 12) DrugCentral uuid:e94ab64e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epoprostenol is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e94adf0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epoprostenol is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e94b07b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eprosartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e94b30d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eprosartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e94b5964-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eprosartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e94b85c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eprosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e94b85c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eprosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e94bc228-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e94bc228-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e94bc228-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e94c06ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:1040 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eptifibatide is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:e94c06ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:1040 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eptifibatide is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:e94c3a8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:e94c6372-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e94c8bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:e94cb494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.333']} DrugCentral uuid:e94cdd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:e94d062e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.58']} DrugCentral uuid:e94d2ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:e94d5778-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:e94d80fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:e94da98a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.714']} DrugCentral uuid:e94dd220-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e94dfa8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.367']} DrugCentral uuid:e94e237e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e94e4c00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.889']} DrugCentral uuid:e94e7496-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e94e9d2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:e94ec66c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:e94eeef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.621']} DrugCentral uuid:e94f1798-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.722']} DrugCentral uuid:e94f4010-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:e94f6a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:e94f9312-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.099']} DrugCentral uuid:e94fbb9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e94fe506-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.354']} DrugCentral uuid:e9500e00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e95037b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:e9506062-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e95089ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:e950b256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e950d6d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.754']} DrugCentral uuid:e950ff72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.836']} DrugCentral uuid:e951290c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:e951535a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.064']} DrugCentral uuid:e9517bdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:e951a47c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:e951cd76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e951f5f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.742']} DrugCentral uuid:e9521e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.487']} DrugCentral uuid:e9524706-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e952701e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e952994a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e952c1d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:e952ea6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:e9531398-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.514']} DrugCentral uuid:e9533c1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.342']} DrugCentral uuid:e953649c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.041']} DrugCentral uuid:e9538d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e953b942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.11']} DrugCentral uuid:e953e1b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e9540b18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e954341c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:e9545cbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:e954853e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:e954add4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08786 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets GPCR (Cholecystokinin A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:e954d7a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O32393 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine targets Unclassified (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:e95500ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35364 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e955294e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e95551d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e9557b10-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00206 biolink:molecularly_interacts_with DrugCentral:1044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eritoran targets Membrane receptor (Toll-like receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e955a392-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:e955cc1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e955f4aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e9561db8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e9564798-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:e956701a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:e956989c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:e956c33a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:e956ebee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e957147a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e9573cde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:e9576628-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:e9578ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:e957b72c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:e957e012-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:e9580998-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e9583224-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e9585ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:e9588828-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:e958b0b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e958d94a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e95901e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:e9592b52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e95953de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:e9597c60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:e959a4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:e959ce04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e959f686-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e95a1f08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:e95a478a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e95a7340-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:e95a9bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e95ac462-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e95aed52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:e95b15e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e95b3e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:e95b670a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e95b8fd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:e95bb854-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:e95be0ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:e95c0a66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e95c364e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e95c5fe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:e95c8888-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e95cb10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:e95cda18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e95d02a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e95d2b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e95d53b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:e95d7cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e95da538-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e95dcdc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e95df768-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e95e231e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:e95e4be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e95e7472-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e95e9d62-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:e95ec5ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:e95eee7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e95f1710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e95f4014-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:e95f6882-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e95f9118-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e95fb986-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e95fe3f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e9600dd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:e960365e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:e9605ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:e96087f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:e960b084-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:e960d910-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:e961019c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e9612a64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e96152fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e9617b86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e961a534-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:e961cdc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:e961f642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:e9621ece-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:e96248e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e9627162-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e9629a02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31152 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e962c298-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e962eb92-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e9631400-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e9633c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:e96364fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e9639092-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e963b946-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e963e1c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:e9640b26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e964342a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e9645ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:e964852e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:e964ae28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e964d6b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:e964ff4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e96527ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e96551b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:e9657a60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:e965a2d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:e965cb8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94956 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib is inhibitor of Transporter (Solute carrier organic anion transporter family member 2B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:e965f49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:1045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e9661d12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:1046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:e966415c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:e96665ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:1046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertapenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:e9668aea-ac81-11ec-8b6b-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:e966af48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:1046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertapenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:e966d3ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertapenem is inhibitor of Enzyme (D-alanyl-D-alanine carboxypeptidase DacB) DrugCentral uuid:e966f82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:1046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertapenem is inhibitor of Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e9671c8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:1046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertapenem is inhibitor of Enzyme (Penicillin-binding protein 1B) DrugCentral uuid:e96743f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erythromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:e9676c62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erythromycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:e96794d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erythromycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:e967bdb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:1048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erythromycin targets GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:e967e660-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erythromycin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e9680fd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erythromycin propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:e968398a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erythromycin propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:e9686270-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 escitalopram is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:e9688b06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 escitalopram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.186']} DrugCentral uuid:e968b392-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 escitalopram targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:e968dc1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 escitalopram targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.412']} DrugCentral uuid:e969068a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 escitalopram targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.706']} DrugCentral uuid:e9692f34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 escitalopram targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:e96957ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 escitalopram targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e969806a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 escitalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:e969a96e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 escitalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e969d204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esmolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e969fa86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esmolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:e96a2326-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esmolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:e96a501c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esomeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:e96a501c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esomeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:e96a8654-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e96a8654-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e96a8654-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e96ac61e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:e96ac61e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:e96ac61e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:e96b078c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:e96b078c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:e96b078c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:e96b476a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:e96b476a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:e96b476a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:e96b8144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.243']} DrugCentral uuid:e96ba9c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.538']} DrugCentral uuid:e96bd252-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.725']} DrugCentral uuid:e96bfae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.926']} DrugCentral uuid:e96c23f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:e96c4c6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:e96c750e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol is activator of Ion channel (Calcium-activated potassium channel subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e96c9eda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:e96cc7b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:e96cf010-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e96d1a5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:e96d434e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.83']} DrugCentral uuid:e96d6bee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:e96d9484-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95718 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Nuclear hormone receptor (Steroid hormone receptor ERR2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:e96dbd1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:e96de614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.947']} DrugCentral uuid:e96e0e96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.372']} DrugCentral uuid:e96e372c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:e96e5fb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:e96e8b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08537 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:e96eb56c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19785 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:e96edde4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e96f0a4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:e96f0a4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:e96f3f82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:e96f6804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.767']} DrugCentral uuid:e96f909a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.133']} DrugCentral uuid:e96fb9b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.637']} DrugCentral uuid:e96fe248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.446']} DrugCentral uuid:e9700ae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:e970336a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:e9705cd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.94']} DrugCentral uuid:e9708572-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.638']} DrugCentral uuid:e970adf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.156']} DrugCentral uuid:e970d694-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1058 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol benzoate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.902']} DrugCentral uuid:e970fff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1059 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol cypionate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:e9712446-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1062 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol mustard targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e9714cfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol valerate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:e971714e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estramustine phosphate is modulator of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:e971962e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:1066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estramustine phosphate targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:e971bea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:1066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estramustine phosphate targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:e971e750-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:1066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estramustine phosphate targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:e9720fdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol succinate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:e9723ba6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol succinate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:e97265ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol succinate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:e9728f02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol succinate targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:e972b810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol succinate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:e972e1c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol succinate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.63']} DrugCentral uuid:e9730a40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol succinate targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:e9733394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol succinate targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:e9735ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol succinate targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:e973851a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e973adec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:e973d696-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:e9740134-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:e97434c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e97434c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e97434c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:e974748e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:e974748e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:e974748e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:e974b534-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:e974b534-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:e974b534-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:e974f526-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:e974f526-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:e974f526-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:e97535a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:e97535a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:e97535a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:e975756e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:e975756e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:e975756e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:e975ad9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1071 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethacrynic acid is inhibitor of Transporter (Solute carrier family 12 member 1) DrugCentral uuid:e975d3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:1071 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethacrynic acid targets Enzyme (Glutathione S-transferase P) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:e975fe4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08263 biolink:molecularly_interacts_with DrugCentral:1071 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethacrynic acid targets Enzyme (Glutathione S-transferase A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e97627d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1071 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethacrynic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.939']} DrugCentral uuid:e9765056-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:1071 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethacrynic acid targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e976798c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:1071 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethacrynic acid targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e976a20e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethambutol targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:e976ca68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:e976f2ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e9771bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e9774448-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WNL8 biolink:molecularly_interacts_with DrugCentral:1073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase A) DrugCentral uuid:e97769dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WNL6 biolink:molecularly_interacts_with DrugCentral:1073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase B) DrugCentral uuid:e9778e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WNL5 biolink:molecularly_interacts_with DrugCentral:1073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase C) DrugCentral uuid:e977b4be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethambutol targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:e977dd68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WNL9 biolink:molecularly_interacts_with DrugCentral:1073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethambutol is inhibitor of Enzyme (Probable arabinosyltransferase A) DrugCentral uuid:e97801c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1076 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethanol targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:e978262e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1076 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethanol targets Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:e9784b2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:1076 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethanol targets Ion channel (Glycine receptor subunit alpha-2) DrugCentral uuid:e9787764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:e9787764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:e9787764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:e978b7e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e978b7e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e978b7e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:e978f09a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:e979193a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e97941da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.964']} DrugCentral uuid:e9796a7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:e9799694-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:e979bf48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.022']} DrugCentral uuid:e979e7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:e97a1204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e97a3ab8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.353']} DrugCentral uuid:e97a6358-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:e97a8c16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.985']} DrugCentral uuid:e97ab52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.83']} DrugCentral uuid:e97addce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e97b0664-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e97b2efa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.81']} DrugCentral uuid:e97b592a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:e97b81de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.246']} DrugCentral uuid:e97baa60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.857']} DrugCentral uuid:e97bd31e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:e97bfc7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:e97c2526-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethinylestradiol targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:e97c4d9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WIE4 biolink:molecularly_interacts_with DrugCentral:1083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethionamide targets Enzyme (Catalase-peroxidase) DrugCentral uuid:e97c7224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:1083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethionamide is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) DrugCentral uuid:e97c9718-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethionamide targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e97cc0bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1084 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethisterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:e97ce970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1084 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethisterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.78']} DrugCentral uuid:e97d1206-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1084 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethisterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:e97d3bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1084 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethisterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.111']} DrugCentral uuid:e97d6454-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1084 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethisterone targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:e97d8cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1086 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:e97db148-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1086 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 profenamine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:e97dd646-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1086 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 profenamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.61']} DrugCentral uuid:e97dfed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1086 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 profenamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e97e2844-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1086 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 profenamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:e97e51ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1086 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:e97e7a4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1086 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:e97ea2d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1086 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 profenamine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:e97ecb6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1086 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 profenamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:e97ef4e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1087 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethosuximide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:e97f3bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:e97f3bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:e97f3bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:e97f3bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:e97f3bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:e97f3bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:e97f3bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:e97f3bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:e97f3bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:e97f3bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:e97fb9f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:e97fe2b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:e9800b64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:e980349a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:e9805d44-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:e98085ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e980aea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:e980d9cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:e98104a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:e9812d46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e98155fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:e9817f4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:e981a8e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e981d28c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e981fb9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e9822458-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e9824d2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e98275ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e9829fd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:e982c8c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e982f162-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:e98319f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:e9834342-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:e9836bce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:e98394f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:e983bd90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:e983e68a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:e9840f2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:e9843bc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e9843bc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e984708c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:e984992c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:e984c1b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:e984ea3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethoxzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:e985135c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:1091 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethyl biscoumacetate targets Enzyme (Vitamin K epoxide reductase complex subunit 1) DrugCentral uuid:e98537ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethylestrenol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:e985605a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethylestrenol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:e98588f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethylestrenol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.983']} DrugCentral uuid:e985b2f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethylestrenol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:e985dbb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethylestrenol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:e9860028-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethylestrenol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:e98628be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethylestrenol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.889']} DrugCentral uuid:e986535c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethylestrenol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:e9867c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethylestrenol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:e986a4a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etynodiol targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:e986c918-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etynodiol is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:e986ee20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etynodiol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.368']} DrugCentral uuid:e98716b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etynodiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:e9873f60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etynodiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:e987680a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e9878e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:e987b27e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:e987d754-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etidocaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:e987ffcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e98829b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etidocaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:e9885242-ac81-11ec-8b6b-0242ac110002 UniProtKB:B1LRJ1 biolink:molecularly_interacts_with DrugCentral:1098 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etidronic acid targets Unclassified (Type IV secretion-like conjugative transfer relaxase protein TraI) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e9887aec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1100 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etilamfetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:e988a3a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1101 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etilefrine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:e988d0dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e988d0dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e988d0dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e98917b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:e98917b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:e98917b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:e98957fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:e98957fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:e98957fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:e9899922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:e9899922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:e9899922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:e989d176-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etodolac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e989fbc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1103 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etodolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.577']} DrugCentral uuid:e98a2450-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:1107 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etofylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:e98a4cf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etomidate targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e98a7554-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etomidate targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e98a9e94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etomidate targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:e98ac720-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etomidate targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:e98af772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:e98af772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:e98af772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:e98b3e94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e98b3e94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e98b3e94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e98b7d82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etonogestrel targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:e98ba1d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etonogestrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:e98bc6e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etonogestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:e98bef6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:e98c192c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.051']} DrugCentral uuid:e98c41a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.071']} DrugCentral uuid:e98c6ada-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:e98c9370-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.282']} DrugCentral uuid:e98cbcf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.21']} DrugCentral uuid:e98ce596-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:e98d0a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:e98d3302-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:e98d5756-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:e98d7bb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:1112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:e98da0da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:1112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide targets Transporter (Canalicular multispecific organic anion transporter 2) DrugCentral uuid:e98dc52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:1112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:e98dedc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.497']} DrugCentral uuid:e98e1650-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoricoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e98e3f9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:e98e6812-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoricoxib targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.102']} DrugCentral uuid:e98e909e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoricoxib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:e98eb920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e98ee210-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e98f0b28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etravirine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:e98f33be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etravirine targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:e98f5c4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etravirine targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:e98f877e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etravirine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e98fb014-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:1115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etravirine targets Transporter (Canalicular multispecific organic anion transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:e98fd8a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:1115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etravirine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e990012c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etravirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:e9902634-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etravirine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:e9904f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etravirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:e9907792-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:1115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etravirine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:e990a082-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:1116 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etretinate is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) DrugCentral uuid:e990c620-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:1116 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etretinate is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) DrugCentral uuid:e990ea6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1117 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etryptamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.63']} DrugCentral uuid:e99112e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1117 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etryptamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:e9913bfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1117 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etryptamine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:e9916710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 everolimus targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:e9918b8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:1118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 everolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:e991b3fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:1118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 everolimus is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e991dd30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 exemestane targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:e99202e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 exemestane is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.692']} DrugCentral uuid:e9922b78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:1123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 exenatide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.18']} DrugCentral uuid:e9925418-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32301 biolink:molecularly_interacts_with DrugCentral:1123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 exenatide targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:e9927d12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHC9 biolink:molecularly_interacts_with DrugCentral:1125 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ezetimibe is antagonist of Membrane other (Niemann-Pick C1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:e992a5c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6T3U3 biolink:molecularly_interacts_with DrugCentral:1125 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ezetimibe targets Unclassified (Niemann-Pick C1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e992ce84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1126 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fadrozole is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e992f71a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1126 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fadrozole is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e993217c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15539 biolink:molecularly_interacts_with DrugCentral:1126 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fadrozole targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:e9934aa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1126 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fadrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:e9937334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1128 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:e9939792-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09252 biolink:molecularly_interacts_with DrugCentral:1128 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famciclovir targets Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:e993bc9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.93']} DrugCentral uuid:e993e530-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:e9940dd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:e9943670-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:e9945f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e99488be-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:e994b15e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:e994ddb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:e9950992-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e99532a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:e9955b4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:e99584a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:e995ad48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:e995d5f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:e995fe74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:e9962764-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:e9964fd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.304']} DrugCentral uuid:e9967872-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famotidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:e996a0f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:1130 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 famprofazone targets Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:e996cb88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e996f72a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.44']} DrugCentral uuid:e99721be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e9974a40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e9977380-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e997a058-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13500 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil targets Cytokine (C-C motif chemokine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e997c8d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e997f332-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:e9981b96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62868 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e9984440-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:e9986cf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:1132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fasudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:e998962a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 febuxostat targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:e998bec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:1137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 febuxostat is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:e998eaa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:1137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 febuxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e9991384-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:1137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 febuxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e9993cc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1140 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felbamate is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 2A) DrugCentral uuid:e999614a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1140 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felbamate is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.284']} DrugCentral uuid:e99989ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1141 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felbinac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:e999ae66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1141 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felbinac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.049']} DrugCentral uuid:e999d760-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:e99a0064-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:e99a28fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:e99a4d9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:e99a72d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.339']} DrugCentral uuid:e99a9b46-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.168']} DrugCentral uuid:e99ac3fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e99aec86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine is activator of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e99b1d78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:e99b1d78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:e99b1d78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:e99b5cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenbufen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:e99b852e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenbufen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:e99bae64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenbufen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:e99bd2cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenbufen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:e99bf734-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1148 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fendiline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e99c1fca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:1148 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fendiline targets GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e99c490a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:1148 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fendiline targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:e99c716e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:1148 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fendiline targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e99c99f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35384 biolink:molecularly_interacts_with DrugCentral:1148 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fendiline is positive allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:e99cc330-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.004']} DrugCentral uuid:e99cec16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:e99d14ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.428']} DrugCentral uuid:e99d3d4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:e99d65d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.172']} DrugCentral uuid:e99d8f2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.845']} DrugCentral uuid:e99db8c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:e99de166-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:e99e09f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.042']} DrugCentral uuid:e99e3634-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:e99e5ec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:e99e8760-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.717']} DrugCentral uuid:e99eb05a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.016']} DrugCentral uuid:e99ed8d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.726']} DrugCentral uuid:e99f014a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.489']} DrugCentral uuid:e99f29cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:e99f52e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:e99f7b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.195']} DrugCentral uuid:e99fa3e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.735']} DrugCentral uuid:e99fcc6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:e99ff730-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:e9a02278-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.673']} DrugCentral uuid:e9a04dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:e9a076e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:e9a09fd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.331']} DrugCentral uuid:e9a0c9e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.032']} DrugCentral uuid:e9a0f284-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.164']} DrugCentral uuid:e9a11c28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:e9a144b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.808']} DrugCentral uuid:e9a16d54-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e9a195e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:e9a1bfb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:e9a1e87e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenofibrate targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:e9a210f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e9a23982-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:e9a26272-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:e9a28b08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e9a2b3b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e9a2dc3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e9a30588-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e9a32e28-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e9a35e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e9a35e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e9a35e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e9a39fb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:e9a3c860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoldopam targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:e9a3f0c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:e9a4195a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:e9a4424a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:e9a46ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:e9a46ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:e9a4a3c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N695 biolink:molecularly_interacts_with DrugCentral:1154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoprofen is inhibitor of Transporter (Sodium-coupled monocarboxylate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:e9a4cd00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1155 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:e9a4f582-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1155 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:e9a51e0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.001']} DrugCentral uuid:e9a54686-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:e9a57110-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:e9a59afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:e9a5c390-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:e9a5ec30-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:e9a61516-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9a63d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:e9a66638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:e9a68eba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:e9a6b854-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e9a6e0d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:e9a7096c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:e9a731e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e9a769b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:e9a769b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:e9a769b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:e9a769b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:e9a7b7ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:e9a7b7ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:e9a7ec2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:e9a814a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e9a83de6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentanyl targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:e9a8665e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1165 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fentiazac targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:e9a88f94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1170 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fexofenadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:e9a8b7ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1170 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fexofenadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e9a8e098-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1170 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fexofenadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e9a90b40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:1170 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fexofenadine targets Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e9a93480-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 finasteride targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e9a95d20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 finasteride targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e9a985a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14060 biolink:molecularly_interacts_with DrugCentral:1171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 finasteride targets Enzyme (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e9a9ae88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24008 biolink:molecularly_interacts_with DrugCentral:1171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 finasteride targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:e9a9d71e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 finasteride targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:e9aa0388-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 finasteride targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:e9aa0388-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 finasteride targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:e9aa3790-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:1171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 finasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:e9aa60c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18405 biolink:molecularly_interacts_with DrugCentral:1171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 finasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:e9aa893e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flavoxate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.704']} DrugCentral uuid:e9aabd96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:e9aabd96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:e9aabd96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:e9aabd96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:e9ab07c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:1175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 7) DrugCentral uuid:e9ab07c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:1175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 7) DrugCentral uuid:e9ab3afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:1175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 8) DrugCentral uuid:e9ab3afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:1175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 8) DrugCentral uuid:e9ab6958-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flecainide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:e9ab9252-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flecainide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:e9abbac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flecainide targets Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.745']} DrugCentral uuid:e9abe41e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:1176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:e9ac0caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flecainide targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.77']} DrugCentral uuid:e9ac35d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:1176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e9ac5e76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63881 biolink:molecularly_interacts_with DrugCentral:1176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flecainide targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e9ac86f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:1176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e9acaff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1177 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fleroxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:e9acdb08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 floctafenine is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:e9ad0394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 floctafenine is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.268']} DrugCentral uuid:e9ad2c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:1180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flopropione is inhibitor of Enzyme (Catechol O-methyltransferase) DrugCentral uuid:e9ad510a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 floxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:e9ad7572-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 floxacillin targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:e9ad9dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:1183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 floxacillin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:e9adc676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1184 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 floxuridine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:e9adeb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:1184 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 floxuridine targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:e9ae13f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e9ae3c8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:e9ae6626-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:e9ae9006-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:e9aeb900-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e9aee18c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:e9af0a22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:1187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:e9af331c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:1187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:e9af5ba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:1187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluconazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e9af8448-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7Z1V1 biolink:molecularly_interacts_with DrugCentral:1187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluconazole targets Enzyme (Sterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:e9afac98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flucytosine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e9afd6b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0CS13 biolink:molecularly_interacts_with DrugCentral:1188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flucytosine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:e9affb3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12461 biolink:molecularly_interacts_with DrugCentral:1188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flucytosine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:e9b01fac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02829 biolink:molecularly_interacts_with DrugCentral:1188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flucytosine targets Cytosolic other (ATP-dependent molecular chaperone HSP82) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:e9b04824-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludarabine phosphate is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e9b0731c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludarabine phosphate is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e9b09eb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludarabine phosphate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:e9b0c790-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:e9b0f026-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e9b11934-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e9b141d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludarabine phosphate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:e9b16a7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:1189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludarabine phosphate is inhibitor of Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:e9b18ed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludrocortisone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e9b1b7e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludrocortisone acetate targets Cytosolic other (Annexin A1) DrugCentral uuid:e9b1dc5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludrocortisone acetate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:e9b204fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:e9b22e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:e9b25966-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:e9b281fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:e9b2aa92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e9b2d382-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:e9b2fbdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e9b3245e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e9b34cf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:e9b375ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:e9b39e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6UVM3 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid is activator of Ion channel (Potassium channel subfamily T member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:e9b3c7b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e9b3f032-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94759 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:e9b41c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:e9b447ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e9b47232-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:e9b49aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZQ8 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:e9b4c3a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7TN37 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e9b4ec4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:e9b514e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:e9b53dfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:e9b5667e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:e9b58f1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flufenamic acid is agonist of GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.863']} DrugCentral uuid:e9b5b76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1194 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:e9b5e130-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e9b60c1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:e9b634be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:e9b65d54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e9b68676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e9b6b6fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:e9b6b6fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:e9b6b6fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:e9b6fdd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:e9b6fdd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:e9b6fdd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:e9b74692-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:e9b74692-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:e9b74692-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:e9b78db4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:e9b78db4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:e9b78db4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b809f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9b8f0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:e9b8f0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:e9b8f0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:e9b8f0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:e9b8f0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:e9b8f0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:e9b95a86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:e9b95a86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:e9b95a86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:e9b9a2e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e9b9a2e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e9b9a2e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e9b9e9ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e9b9e9ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e9b9e9ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:e9ba3136-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:e9ba3136-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:e9ba3136-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9baa9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:e9bb82f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1198 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flumetasone pivalate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:e9bba76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.621']} DrugCentral uuid:e9bbd018-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:e9bbf908-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.713']} DrugCentral uuid:e9bc21a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:e9bc4a52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.662']} DrugCentral uuid:e9bc72fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e9bc9c0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.304']} DrugCentral uuid:e9bcc496-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:e9bcecfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:e9bd159a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:e9bd4042-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:e9bd6a18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:e9bd92a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.455']} DrugCentral uuid:e9bdbb3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:e9bde43e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:e9be0dce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:e9be365a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.151']} DrugCentral uuid:e9be5efa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.504']} DrugCentral uuid:e9be883a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.103']} DrugCentral uuid:e9beb0da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e9bed966-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:e9bf02c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e9bf2ef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.333']} DrugCentral uuid:e9bf5986-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.532']} DrugCentral uuid:e9bf8230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.357']} DrugCentral uuid:e9bfab2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:e9bfd3c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:e9bffc4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:e9c024d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:e9c04e0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e9c076a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e9c09f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e9c0c7a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:e9c0f2a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:e9c1241e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e9c1241e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e9c1241e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e9c16348-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y256 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:e9c18c06-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:e9c1b47e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e9c1ddf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:e9c206a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:e9c22ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:e9c2588e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunisolide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:e9c28106-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunisolide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:e9c2a9b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:e9c2d624-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:e9c2ff6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e9c3280e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:e9c358c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e9c358c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e9c358c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e9c39fa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e9c39fa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e9c39fa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:e9c3e758-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:e9c3e758-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:e9c3e758-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:e9c42e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:e9c42e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:e9c42e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:e9c47524-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:e9c47524-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:e9c47524-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:e9c4c114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:e9c4c114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:e9c4c114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c53b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9c61636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:e9c61636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:e9c61636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:e9c65e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e9c65e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e9c65e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:e9c6a628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e9c6a628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e9c6a628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e9c6ed04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e9c6ed04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e9c6ed04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:e9c73430-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e9c73430-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e9c73430-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:e9c77364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1204 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluocinolone acetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.848']} DrugCentral uuid:e9c79c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1204 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluocinolone acetonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.475']} DrugCentral uuid:e9c7c53a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1205 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluocinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.622']} DrugCentral uuid:e9c7edd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1205 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluocinonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.538']} DrugCentral uuid:e9c8167a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1207 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorescein targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.042']} DrugCentral uuid:e9c8414a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:1207 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorescein targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:e9c86cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:1207 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorescein targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:e9c8958c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:1207 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorescein targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:e9c8be40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1208 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorometholone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.801']} DrugCentral uuid:e9c8e726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1208 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorometholone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.067']} DrugCentral uuid:e9c910de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1208 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorometholone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:e9c9396a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:e9c96264-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:e9c98b04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:e9c9b44e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:e9c9dcda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.091']} DrugCentral uuid:e9ca06a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:e9ca2f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:e9ca580e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e9ca8090-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:e9caa980-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e9cad202-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e9cafa70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:e9cb2306-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:e9cb4c28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.959']} DrugCentral uuid:e9cb74aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.047']} DrugCentral uuid:e9cb9d18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:e9cbc586-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e9cbf09c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.538']} DrugCentral uuid:e9cc1928-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:e9cc41a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.444']} DrugCentral uuid:e9cc6a22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:e9cc92fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e9ccbbf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e9cce45c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e9cd0d92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e9cd3614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:e9cd5ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e9cd8740-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:e9cdb21a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:e9cddb32-ac81-11ec-8b6b-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:e9ce03b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:e9ce2c40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:e9ce553a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:e9ce896a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e9ce896a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e9ce896a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e9ce896a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:e9cedce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e9cedce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e9cedce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:e9cf24ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e9cf24ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e9cf24ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:e9cf63e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:e9cf8e5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25122 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine targets Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:e9cfb8e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxetine is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e9cfe184-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoxymesterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:e9d00a24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:e9d03328-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9d05bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.65']} DrugCentral uuid:e9d08418-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:e9d0acae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.058']} DrugCentral uuid:e9d0d5e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:e9d0fb28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:e9d123d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e9d14c4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.066']} DrugCentral uuid:e9d1785a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:e9d1a118-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:e9d1c9a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:e9d1f280-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:e9d21b16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:e9d252fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e9d252fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e9d252fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e9d252fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e9d252fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:e9d2a946-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.075']} DrugCentral uuid:e9d2d1d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.649']} DrugCentral uuid:e9d2fa7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.269']} DrugCentral uuid:e9d32394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.503']} DrugCentral uuid:e9d34cf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.067']} DrugCentral uuid:e9d37588-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:e9d39e32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:e9d3c718-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.711']} DrugCentral uuid:e9d3f0c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.838']} DrugCentral uuid:e9d4193e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.044']} DrugCentral uuid:e9d441de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:e9d46b0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:e9d49490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.464']} DrugCentral uuid:e9d4bd12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:e9d4e5b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.191']} DrugCentral uuid:e9d50f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.087']} DrugCentral uuid:e9d53814-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:e9d56082-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.887']} DrugCentral uuid:e9d58918-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.793']} DrugCentral uuid:e9d5b1e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:e9d5da80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e9d60302-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.575']} DrugCentral uuid:e9d62ba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.999']} DrugCentral uuid:e9d654ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.315']} DrugCentral uuid:e9d67d50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.447']} DrugCentral uuid:e9d6a5e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.655']} DrugCentral uuid:e9d6ce68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:e9d6f7ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:e9d72070-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.539']} DrugCentral uuid:e9d74906-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.788']} DrugCentral uuid:e9d7720a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:e9d79a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.535']} DrugCentral uuid:e9d7c32c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.019']} DrugCentral uuid:e9d7ebae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:e9d814e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.005']} DrugCentral uuid:e9d83d70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.072']} DrugCentral uuid:e9d86610-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:e9d88f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:e9d8ba66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.397']} DrugCentral uuid:e9d8e612-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:e9d91092-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.097']} DrugCentral uuid:e9d93914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.708']} DrugCentral uuid:e9d961f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.125']} DrugCentral uuid:e9d98a90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e9d9b326-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.67']} DrugCentral uuid:e9d9de00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:e9da06aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.061']} DrugCentral uuid:e9da2f36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.049']} DrugCentral uuid:e9da57ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:e9da81c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:e9daad30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:e9dad7ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e9db0082-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:e9db2986-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:e9db59ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:e9db59ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:e9db59ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:e9dbb43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e9dbb43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e9dbb43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e9dbb43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e9dbb43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e9dbb43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e9dbb43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e9dbb43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:e9dc2d18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1213 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine decanoate is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:e9dc527a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:e9dc7e30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.268']} DrugCentral uuid:e9dca72a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.503']} DrugCentral uuid:e9dccfb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.225']} DrugCentral uuid:e9dcf892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.837']} DrugCentral uuid:e9dd2146-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:e9dd49dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.048']} DrugCentral uuid:e9dd725e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:e9dd9b76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:e9ddc402-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:e9ddec98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.087']} DrugCentral uuid:e9de1524-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.611']} DrugCentral uuid:e9de3fb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.887']} DrugCentral uuid:e9de684e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:e9de90d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:e9debab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.961']} DrugCentral uuid:e9dee396-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.145']} DrugCentral uuid:e9df0c2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.841']} DrugCentral uuid:e9df349a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.274']} DrugCentral uuid:e9df5dda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.447']} DrugCentral uuid:e9df863e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:e9dfafce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:e9dfd850-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.539']} DrugCentral uuid:e9e00230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:e9e02d32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:e9e055c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:e9e07e36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:e9e0a726-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:1215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupirtine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e9e0cf76-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:1215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupirtine targets Ion channel (Potassium voltage-gated channel subfamily KQT member 3) DrugCentral uuid:e9e0f3fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:1215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flupirtine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:e9e11c88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1216 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluprednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:e9e14258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludroxycortide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.695']} DrugCentral uuid:e9e16af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fludroxycortide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:e9e1938e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1218 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurazepam targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.222']} DrugCentral uuid:e9e1c3f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e9e1c3f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e9e1c3f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:e9e2053a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurbiprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:e9e22dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurbiprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:e9e25652-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurbiprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:e9e27f42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurbiprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:e9e2a7ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:1219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurbiprofen targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:e9e2d050-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurbiprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:e9e2f8dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e9e321fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e9e34a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:e9e373e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:e9e39c7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:e9e3c8ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.436']} DrugCentral uuid:e9e3f1c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.244']} DrugCentral uuid:e9e41a5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e9e44372-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:e9e46d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:e9e495de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:e9e4be88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:e9e4e7c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:e9e51068-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:e9e53908-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:e9e5619e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.951']} DrugCentral uuid:e9e58ca0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:e9e5b77a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.208']} DrugCentral uuid:e9e5dff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.056']} DrugCentral uuid:e9e60892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e9e63150-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e9e65a22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:1222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluspirilene targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e9e682ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flutamide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:e9e6ab44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flutamide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.082']} DrugCentral uuid:e9e6d4ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:e9e6fd56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flutamide targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:e9e725ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.049']} DrugCentral uuid:e9e74f4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flutamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:e9e778e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.74']} DrugCentral uuid:e9e7a166-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:e9e7ca6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.77']} DrugCentral uuid:e9e7f328-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47712 biolink:molecularly_interacts_with DrugCentral:1225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone propionate targets Enzyme (Cytosolic phospholipase A2) DrugCentral uuid:e9e8179a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:1225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone propionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.12']} DrugCentral uuid:e9e84030-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1227 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flutrimazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:e9e868a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1227 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flutrimazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:e9e891ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:e9e8b646-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvastatin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:e9e8ded2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:1229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvastatin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.96']} DrugCentral uuid:e9e90786-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:1229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:e9e9318e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvastatin targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e9e95a1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvastatin targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e9e982c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:e9e9ab50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvoxamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:e9e9d45e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvoxamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:e9e9fcea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvoxamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.951']} DrugCentral uuid:e9ea2576-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvoxamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:e9ea4f2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvoxamine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:e9ea786e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvoxamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:e9eaa104-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1230 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluvoxamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:e9eac99a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 folic acid targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:e9eaf230-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 folic acid targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:e9eb21e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1232 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leucovorin targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.071']} DrugCentral uuid:e9eb4a82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:1232 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leucovorin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:e9eb7be2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:e9eb7be2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:e9eb7be2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:e9ebb8a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:1233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fomepizole targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e9ebb8a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:1233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fomepizole targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:e9ebecb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:1236 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fondaparinux is activator of Secreted (Antithrombin-III) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:e9ec1534-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1238 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 formestane targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:e9ec3e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 formoterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:e9ec6728-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 formoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:e9ec8fe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 formoterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:e9ecb872-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 formoterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:e9ece3a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 formoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:e9ed0c6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 formoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:e9ed34dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 formoterol targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:e9ed5dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1240 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosamprenavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:e9ed82ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1240 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosamprenavir is inhibitor of Enzyme (Pol polyprotein) DrugCentral uuid:e9eda728-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 foscarnet is inhibitor of Enzyme (DNA polymerase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:e9edcfc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08546 biolink:molecularly_interacts_with DrugCentral:1241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 foscarnet targets Enzyme (DNA polymerase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e9edf84a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 foscarnet targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:e9ee218a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 foscarnet targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e9ee4a02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosfluconazole targets Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:e9ee6e60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q836E5 biolink:molecularly_interacts_with DrugCentral:1243 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1) DrugCentral uuid:e9ee92d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q831A8 biolink:molecularly_interacts_with DrugCentral:1243 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2) DrugCentral uuid:e9eeba5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A749 biolink:molecularly_interacts_with DrugCentral:1243 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosfomycin is inhibitor of Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e9eee4b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HVW7 biolink:molecularly_interacts_with DrugCentral:1243 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:e9ef0d52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosinopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:e9ef35c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosinopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:e9ef5faa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1247 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosphenytoin is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e9ef8412-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 frovatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e9efacd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 frovatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:e9efd6ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 frovatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:e9f00108-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fructose targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:e9f02980-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1253 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ftivazide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:e9f0520c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:e9f07bce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:e9f0a608-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:e9f0ce9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.68']} DrugCentral uuid:e9f0f72a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant is antagonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:e9f1201a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:e9f1489c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:e9f1711e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:e9f1998c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:e9f1c2b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:e9f1eb44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:1255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fulvestrant targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:e9f213c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furaltadone targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:e9f23c52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:e9f26718-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:e9f28bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:e9f2b484-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e9f2dd1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:e9f3060a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:e9f32e96-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:e9f3581c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e9f38166-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:e9f3aa06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:e9f3d29c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:e9f3fb3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:e9f42530-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:e9f44fc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:e9f4783c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:e9f4a0f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:e9f4c9b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:e9f4f262-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96618 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Enzyme (Holo-[acyl-carrieir-protein] synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:e9f51b02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furosemide targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:e9f54384-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fusidic acid targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:e9f56cb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fusidic acid targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:e9f59532-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e9f5bdaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23978 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:e9f5e744-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31648 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:e9f611d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:e9f63a5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:e9f662f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24046 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:e9f68b5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48066 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:e9f6b430-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48065 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent betaine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:e9f6dcb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31650 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:e9f70520-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31646 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:e9f72f50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31649 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:e9f757be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23574 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:e9f78040-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid is agonist of GPCR (Gamma-aminobutyric acid type B receptor subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:e9f7a8d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSD5 biolink:molecularly_interacts_with DrugCentral:1262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:e9f7d234-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:e9f7f66a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:e9f81abe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin targets GPCR (Adenosine receptor A1) DrugCentral uuid:e9f83f08-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75899 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin targets GPCR (Gamma-aminobutyric acid type B receptor subunit 2) DrugCentral uuid:e9f863d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:e9f88828-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.523']} DrugCentral uuid:e9f8b140-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:e9f8d9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:e9f90316-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:e9f92ba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08532 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:e9f95442-ac81-11ec-8b6b-0242ac110002 UniProtKB:O77773 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin targets Ion channel (Uncharacterized protein; Voltage-dependent calcium channel alpha-2 delta subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:e9f97cf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:1264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.928']} DrugCentral uuid:e9f9a726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galantamine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:e9f9d016-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galantamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:e9f9f8b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:e9fa2142-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:1272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e9fa4a14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:1272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galantamine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:e9fa726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:e9fa9ae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:e9fac372-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:1272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:e9faec80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galantamine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:e9fb162e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galantamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e9fb3ece-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1273 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:e9fb675a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1273 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:e9fb937e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1273 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:e9fbc07e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1273 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:e9fbe996-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:1273 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:e9fc127c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1273 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallamine is blocker of Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:e9fc3b12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1273 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallamine is negative allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:e9fc6b6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:e9fc6b6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:e9fc6b6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:e9fcab2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:1276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gamolenic acid targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:e9fcd39c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:e9fcfc1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:e9fd24a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:1276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:e9fd4e6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:1276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gamolenic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:e9fd76da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:1276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gamolenic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:e9fd9f48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ganciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:e9fdc392-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:1277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ganciclovir targets Kinase (Thymidine kinase) DrugCentral uuid:e9fde840-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13255 biolink:molecularly_interacts_with DrugCentral:1277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ganciclovir targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:e9fe10c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41594 biolink:molecularly_interacts_with DrugCentral:1277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ganciclovir targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:e9fe3944-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10210 biolink:molecularly_interacts_with DrugCentral:1277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ganciclovir targets Enzyme (Capsid scaffolding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:e9fe61c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:1277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ganciclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:e9fe8b88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ganirelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:e9feafdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gatifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:e9fed962-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gatifloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:e9ff05e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:e9ff05e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:e9ff39ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:e9ff39ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:e9ff6bfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gatifloxacin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e9ff6bfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gatifloxacin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:e9ff9fe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:e9ffc8b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:e9fff144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea0019ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ea004284-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ea006bce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ea009464-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:ea00bcfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ea00e5f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ea010f70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ea01391e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ea0161aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ea018a90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:ea01b33a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:ea01dbbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ea02042a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ea022d60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea0255e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:ea027e82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:ea02a7f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:ea02d1ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ea02fa38-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:ea0322c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ea034b5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ea03745e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ea039cea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:ea03c580-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ea03edf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ea041742-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ea043fd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ea046882-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ea049104-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ea04bc24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ea04e596-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ea050e36-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ea05371c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ea05603e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ea0588d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:ea05b174-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ea05da8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ea06030e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ea062ba4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ea0654a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ea067e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea06a7e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ea06d086-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:ea06f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ea072342-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:ea074bd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ea077478-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ea079d22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:ea07c676-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:ea07ef16-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ea0817b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ea084114-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ea086c16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ea0894a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ea08bd2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea08e60a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ea090e96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ea093722-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:ea095fae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ea098902-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31152 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ea09b198-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea09da24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:ea0a027e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea0a2dee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:ea0a5936-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ea0a81ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ea0aab48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:ea0ad44c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:ea0afcd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ea0b2596-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ea0b4ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ea0b778a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ea0ba00c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:ea0bc884-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:ea0bf246-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ea0c1ae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ea0c435e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gefitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ea0c6bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemcitabine targets Enzyme (Thymidylate synthase) DrugCentral uuid:ea0c90b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:1283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemcitabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:ea0cb53c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemcitabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:ea0cd9b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemcitabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:ea0cfe02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30085 biolink:molecularly_interacts_with DrugCentral:1283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemcitabine targets Kinase (UMP-CMP kinase) DrugCentral uuid:ea0d2c6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:ea0d2c6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:ea0d2c6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:ea0d6482-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemfibrozil targets Enzyme (Lipoprotein lipase) DrugCentral uuid:ea0d88b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemfibrozil targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:ea0db144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemfibrozil targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea0ddcb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemfibrozil targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.523']} DrugCentral uuid:ea0e0748-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemfibrozil is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:ea0e2fca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemfibrozil targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:ea0e5860-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemfibrozil targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:ea0e8146-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ea0eaa9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:1286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemifloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:ea0ecf0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P72525 biolink:molecularly_interacts_with DrugCentral:1286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemifloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) DrugCentral uuid:ea0ef36a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gestodene targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:ea0f187c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gestodene targets Enzyme (Cytochrome P450 3A5) DrugCentral uuid:ea0f3cda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1292 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gestrinone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ea0f6584-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12882 biolink:molecularly_interacts_with DrugCentral:1293 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gimeracil is inhibitor of Enzyme (Dihydropyrimidine dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:ea0f8e1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1297 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glafenine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:ea0fb93a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1297 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glafenine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:ea0fe5c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ea0fe5c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ea101dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.046']} DrugCentral uuid:ea101dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.046']} DrugCentral uuid:ea105606-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ea105606-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ea108e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.222']} DrugCentral uuid:ea108e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.222']} DrugCentral uuid:ea10c668-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:ea10c668-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:ea10feee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:ea10feee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:ea1136e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1301 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glipizide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.097']} DrugCentral uuid:ea1136e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1301 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glipizide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.097']} DrugCentral uuid:ea117018-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gliquidone is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ea117018-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gliquidone is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ea11ab6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glisoxepide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.959']} DrugCentral uuid:ea11ab6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glisoxepide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.959']} DrugCentral uuid:ea11e02a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ea120a46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:ea1232e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:ea125b86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P39086 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:ea128426-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ea12ad5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13255 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ea12d5e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00367 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Enzyme (Glutamate dehydrogenase 1, mitochondrial) DrugCentral uuid:ea12fa5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49448 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Enzyme (Glutamate dehydrogenase 2, mitochondrial) DrugCentral uuid:ea131ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:ea1348d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41594 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ea137476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14833 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ea139d2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ea13c5ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13002 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ea13eeba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13003 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ea141746-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14831 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:ea143fa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15303 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:ea14682c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14416 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:ea149144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43003 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:ea14b9e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43004 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:ea14e270-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43005 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:ea150b06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19491 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:ea153734-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.595']} DrugCentral uuid:ea155ffc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16099 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.738']} DrugCentral uuid:ea158888-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14832 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid is agonist of GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ea15b178-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00222 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid is agonist of GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ea15dad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ea16034e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42260 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ea162bda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22756 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ea165510-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31423 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ea167d7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35349 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ea16a600-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19490 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:ea16ce64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19492 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ea16f8c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ea17212a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42264 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.31']} DrugCentral uuid:ea1749ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03469 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Enzyme (Glutamate racemase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ea177238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70579 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ea179b28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47743 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:ea17c38c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31424 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:ea17ed1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23385 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ea181580-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31421 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ea183e8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31422 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ea1866fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56068 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Enzyme (Glutamate racemase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ea188f9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35921 biolink:molecularly_interacts_with DrugCentral:1310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ea18b81e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:1311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutamine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:ea18e302-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2Q3 biolink:molecularly_interacts_with DrugCentral:1312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutathione targets Enzyme (Glutathione S-transferase kappa 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ea191354-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:ea191354-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:ea191354-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:ea194b8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:ea19745c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ea199dd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.795']} DrugCentral uuid:ea19c66e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:ea19ef0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide is blocker of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:ea1a1c68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:ea1a1c68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:ea1a503e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ea1a78c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ea1aa2b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96P20 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide targets Unclassified (NACHT, LRR and PYD domains-containing protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ea1acb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:ea1af3ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide targets Nuclear other (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:ea1b2086-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ESQ5 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide is inhibitor of Ion channel (Sur1-Trpm4; Sulfonylurea receptor 1 - Transient receptor potential melastatin 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:ea1b2086-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ESQ5 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide is inhibitor of Ion channel (Sur1-Trpm4; Sulfonylurea receptor 1 - Transient receptor potential melastatin 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:ea1b58b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.523']} DrugCentral uuid:ea1b58b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.523']} DrugCentral uuid:ea1b8cce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ea1bb546-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48067 biolink:molecularly_interacts_with DrugCentral:1319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycine targets Transporter (Sodium- and chloride-dependent glycine transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ea1bf592-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ea1bf592-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ea1bf592-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ea1bf592-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ea1bf592-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ea1bf592-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ea1bf592-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ea1c61e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycine targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:ea1c8ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:1325 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ea1cbb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:1325 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ea1ce5c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:1325 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:ea1d0f54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:1325 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycyrrhizic acid targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:ea1d37cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:1327 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 goserelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:ea1d5c48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1327 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 goserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:ea1d80ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ea1da9c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:ea1dd24a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ea1dfae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ea1e2380-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07820 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Cytosolic other (Induced myeloid leukemia cell differentiation protein Mcl-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ea1e4e0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:ea1e786c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00346 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Enzyme (Malate dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ea1ea0da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0PJ46 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Enzyme (Lactate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:ea1ec948-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6VVP7 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Enzyme (Malate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:ea1ef224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11708 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Enzyme (Malate dehydrogenase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ea1f1a7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00338 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Enzyme (L-lactate dehydrogenase A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ea1f4314-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92843 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Cytosolic other (Apoptosis regulator Bcl-W) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:ea1f6bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52732 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Enzyme (Kinesin-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:ea1f9508-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11166 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Transporter (Solute carrier family 2, facilitated glucose transporter member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ea1fbd8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29372 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Enzyme (DNA-3-methyladenine glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ea1fe5ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07195 biolink:molecularly_interacts_with DrugCentral:1328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gossypol targets Enzyme (L-lactate dehydrogenase B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ea200f4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 granisetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:ea203af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 granisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ea2066d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 granisetron targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:ea20928c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 granisetron targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ea20bf46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 granisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:ea20bf46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 granisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:ea20f72c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:ea20f72c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:ea212b20-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:1329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 granisetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ea215456-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:ea217cec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1330 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grepafloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ea21a96a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1330 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:ea21a96a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1330 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:ea21dbce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1330 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ea21dbce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1330 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ea220bbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10875 biolink:molecularly_interacts_with DrugCentral:1331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 griseofulvin targets Structural (Tubulin beta chain) DrugCentral uuid:ea22302e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 griseofulvin targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ea2259c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 griseofulvin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:ea228ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:ea228ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:ea228ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:ea22c2f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1334 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guaiacol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:ea22ec08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1334 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guaiacol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:ea2314a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanadrel is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:ea233992-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanadrel targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:ea235ddc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanethidine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:ea238244-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanethidine is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:ea23a698-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanethidine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:ea23cb96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanethidine targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:ea23eff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanethidine targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:ea241448-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanethidine targets GPCR (Alpha-1D adrenergic receptor) DrugCentral uuid:ea2438b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanethidine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:ea245e58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.065']} DrugCentral uuid:ea248716-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:ea24afb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:ea24d860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanfacine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.926']} DrugCentral uuid:ea250182-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanfacine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ea252a18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanfacine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:ea2552b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:1343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanfacine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:ea257b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanfacine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:ea25a6a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanfacine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.164']} DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2668b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea2853dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea291038-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1349 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ulobetasol propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:ea29354a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halofantrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ea296128-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ea298afe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.003']} DrugCentral uuid:ea29b38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ea29dc98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol is inverse agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:ea2a052e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.947']} DrugCentral uuid:ea2a2dce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:ea2a5628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ea2a7f2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ea2aa7d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ea2ad062-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea2af8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea2b23f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ea2b4d4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ea2b75da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ea2b9e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ea2bc72e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ea2befb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:ea2c1828-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ea2c40a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:ea2c69c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol is inverse agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:ea2c924e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ea2cbbca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:ea2ce58c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.999']} DrugCentral uuid:ea2d1160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ea2d3d16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ea2d6692-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.182']} DrugCentral uuid:ea2d8f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.569']} DrugCentral uuid:ea2db804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ea2de09a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:ea2e0930-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:ea2e3270-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:ea2e63da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ea2e63da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ea2e63da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ea2ea2f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.648']} DrugCentral uuid:ea2ecd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ea2ef5c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ea2f1e74-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ea2f46ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ea2f6fc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.305']} DrugCentral uuid:ea2f984a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:ea2fc0d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ea2fe958-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.76']} DrugCentral uuid:ea30127a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ea303b10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ea30639c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea308e6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ea30b73e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ea30dfe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:ea310874-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:ea31315a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:ea3159fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ea318286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ea31ab12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:ea31d452-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ea31fcde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ea32257e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:ea324ee6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ea327970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:ea32a21a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ea32caba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ea32f35a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:ea331c72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:ea3344fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ea336d94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50129 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ea3396d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:ea33bf7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ea33e800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62744 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Unclassified (AP-2 complex subunit sigma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:ea342130-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ea342130-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ea342130-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ea342130-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ea342130-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ea348724-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea348724-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea348724-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea348724-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea34dda0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ea34dda0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ea34dda0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ea34dda0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ea352f9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ea352f9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ea352f9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ea35738c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:ea35738c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:ea35b6bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ea35b6bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ea35b6bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ea35b6bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ea35b6bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ea361634-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea361634-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea361634-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea36618e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:ea36618e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:ea36618e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:ea36bd00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ea36bd00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ea36bd00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ea36bd00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ea36bd00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ea36bd00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ea36bd00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ea36bd00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ea373c26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:ea373c26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:ea373c26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:ea377d44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ea37a5d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:ea37ce70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ea37f9fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea3824c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60493 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol targets Unclassified (Zinc finger protein 664) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:ea384d82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol is inverse agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:ea387622-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1354 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halopredone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:ea389ae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:ea38c366-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.339']} DrugCentral uuid:ea38ec06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.366']} DrugCentral uuid:ea391546-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.561']} DrugCentral uuid:ea393e72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:ea3966fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:ea398f9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:ea39b974-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ea39e61a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:ea3a0e9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.231']} DrugCentral uuid:ea3a3746-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.805']} DrugCentral uuid:ea3a602c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ea3a88b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.338']} DrugCentral uuid:ea3ab144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:ea3ad9e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:1355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloprogin targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ea3b0338-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:ea3b27b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:ea3b4c3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:ea3b70c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:ea3b974e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:ea3bc07a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:ea3bc07a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3c28da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea3ce450-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:1358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 heparin is activator of Secreted (Antithrombin-III) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:ea3d0cdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:1358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 heparin targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.14']} DrugCentral uuid:ea3d3572-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:1358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 heparin targets Unclassified (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.14']} DrugCentral uuid:ea3d5f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:ea3d8afe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:ea3db646-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:ea3ddf04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:1362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hesperetin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:ea3e07cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:1362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hesperetin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:ea3e3076-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hesperetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ea3e58f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:1362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hesperetin targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:ea3e8170-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:1362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hesperetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ea3eaa7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:1362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hesperetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ea3ee642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ea3ee642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ea3ee642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ea3ee642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ea3ee642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ea3ee642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ea3f3c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.212']} DrugCentral uuid:ea3f6590-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.191']} DrugCentral uuid:ea3f8e12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.043']} DrugCentral uuid:ea3fb6b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.686']} DrugCentral uuid:ea3fdfa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.636']} DrugCentral uuid:ea40081a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.441']} DrugCentral uuid:ea4030a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.618']} DrugCentral uuid:ea405946-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.994']} DrugCentral uuid:ea408362-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.442']} DrugCentral uuid:ea40ac16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:ea40d5a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.521']} DrugCentral uuid:ea40fe64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:ea4127ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.882']} DrugCentral uuid:ea41501c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.126']} DrugCentral uuid:ea41789e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.911']} DrugCentral uuid:ea41a170-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06149 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Enzyme (D-lactate dehydrogenase) DrugCentral uuid:ea41c5ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.614']} DrugCentral uuid:ea41ee64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.459']} DrugCentral uuid:ea4216e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.479']} DrugCentral uuid:ea424012-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ea426880-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.605']} DrugCentral uuid:ea429102-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.057']} DrugCentral uuid:ea42b95c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:ea42e288-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.479']} DrugCentral uuid:ea430b0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.708']} DrugCentral uuid:ea433396-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) DrugCentral uuid:ea4357f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:ea4380bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ea43a93e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11142 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Unclassified (Heat shock cognate 71 kDa protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:ea43d1a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMV8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Unclassified (Heat shock 70 kDa protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:ea43fa10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ea442332-ac81-11ec-8b6b-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:ea444b8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:ea4474f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ea449e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6IQ20 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene is inhibitor of Unclassified (N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:ea44c828-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:1364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexachlorophene targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ea44f0b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexafluronium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:ea451526-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexafluronium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ea453dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexafluronium targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ea456aa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:ea456aa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:ea45a27a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ea45a27a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ea45da42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:ea45da42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:ea461a48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea461a48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea461a48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea461a48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ea4665de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ea468fe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamethonium is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:ea46bb7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1368 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexestrol is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:ea46eeb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:ea46eeb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:ea46eeb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:ea472eb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:ea472eb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:ea472eb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:ea476e84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:ea476e84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:ea476e84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:ea47af66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:ea47af66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:ea47af66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:ea47f03e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ea47f03e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ea47f03e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ea482f40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:ea48539e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ea487fea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:ea48a8bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ea48d13e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ea48fa2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:ea492a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ea492a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ea492a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ea4969a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexylresorcinol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ea4992b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexylresorcinol targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:ea49bb26-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexylresorcinol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ea49e3a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine is agonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ea4a0c16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ea4a35f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ea4a5fa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.508']} DrugCentral uuid:ea4a893e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:ea4ab1ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ea4adbf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ea4b0454-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ea4b2cb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:ea4b553a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P58406 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:ea4b7e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q91ZY2 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ea4ba6e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q91ZY1 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ea4bcf6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.84']} DrugCentral uuid:ea4bf7d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q91ZY3 biolink:molecularly_interacts_with DrugCentral:1375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ea4c23fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histidine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ea4c4cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:ea4c7532-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:ea4c9e2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:ea4cc6ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:ea4cef44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:ea4d17da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hycanthone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:ea4d411a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:ea4d697e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:ea4d8dd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 1) DrugCentral uuid:ea4db23a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:ea4dd760-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBC3 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 3B) DrugCentral uuid:ea4dfb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ea4e23c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.438']} DrugCentral uuid:ea4e4c40-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ea4e7526-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ea4e9d9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea4ec5f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0LPN4 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine targets Ion channel (Ryanodine receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.152']} DrugCentral uuid:ea4eef60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92736 biolink:molecularly_interacts_with DrugCentral:1384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydralazine is blocker of Ion channel (Ryanodine receptor 2) DrugCentral uuid:ea4f147c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ea4f3d12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochlorothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.01']} DrugCentral uuid:ea4f656c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ea4f8df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:ea4fb3b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:1385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochlorothiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:ea4fdb00-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochlorothiazide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ea5003c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochlorothiazide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:ea502c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ea50565c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochlorothiazide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:ea507ef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochlorothiazide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:ea50a832-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocodone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:ea50d0dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocodone is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ea50fa3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1387 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortamate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:ea511e98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:ea51471a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone targets Cytosolic other (Annexin A1) DrugCentral uuid:ea516b6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.95']} DrugCentral uuid:ea51956c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:1388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ea51bdda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.881']} DrugCentral uuid:ea51e666-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ea520ee8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:1388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.37']} DrugCentral uuid:ea5237d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone cypionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:ea525c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroflumethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.37']} DrugCentral uuid:ea5284ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydromorphone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:ea52ad44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydromorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:ea52d68e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydromorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ea530bb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ea530bb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ea530bb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ea530bb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ea5356ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:1394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyamfetamine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.1']} DrugCentral uuid:ea538142-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ea53a9c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyamfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.529']} DrugCentral uuid:ea53d23c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:ea53fb2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ea5423c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:ea54483e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:ea5470f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.81']} DrugCentral uuid:ea549a1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:ea54c2b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:ea54eb18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ea5513a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ea553dac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ea556642-ac81-11ec-8b6b-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:ea558aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:ea55b34a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYK1 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine is antagonist of Membrane receptor (Toll-like receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:ea55dd66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine is antagonist of Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ea560660-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:1395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxychloroquine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ea562ee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:1398 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxystilbamidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:ea56573c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ea56804a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:ea56a9d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxycarbamide is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:ea56ce38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxycarbamide is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:ea56f2a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:ea571c6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyzine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ea574502-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyzine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ea576d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyzine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:ea5795fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyzine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.409']} DrugCentral uuid:ea57beec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:1400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyzine targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ea57e75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hymecromone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:ea580fbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hymecromone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:ea5838e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hymecromone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:ea586176-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hymecromone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ea588a0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37058 biolink:molecularly_interacts_with DrugCentral:1401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hymecromone targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ea58b284-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hymecromone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:ea58dc64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ea5907f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ea5930f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:ea595978-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hyoscyamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:ea59825e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hyoscyamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:ea59ab08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:1404 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibandronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:ea59d39e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:1404 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibandronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ea59fc20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02769 biolink:molecularly_interacts_with DrugCentral:1404 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibandronic acid targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ea5a2538-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:1404 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibandronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ea5a4da6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:1406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ea5a761e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:ea5a9f9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:ea5ac92a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08493 biolink:molecularly_interacts_with DrugCentral:1406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ea5af1ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:ea5b1a56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ea5b433c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ea5b6bdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:ea5b9454-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:ea5bbde4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:ea5be314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:ea5c0bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ea5c34c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:ea5c5d30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ea5c86b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ea5caf38-ac81-11ec-8b6b-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ea5cd7a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ea5d0028-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02769 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ea5d28f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ea5d5168-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ea5d79cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ea5da636-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ea5da636-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ea5ddab6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N695 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen is inhibitor of Transporter (Sodium-coupled monocarboxylate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:ea5e0342-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VD48 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ea5e2bba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:1407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuprofen is blocker of Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.53']} DrugCentral uuid:ea5e5586-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuproxam targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:ea5e82fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuproxam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ea5e82fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibuproxam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ea5eb6d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibutilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ea5edf56-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75907 biolink:molecularly_interacts_with DrugCentral:1413 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 icosapent ethyl is inhibitor of Enzyme (Diacylglycerol O-acyltransferase 1) DrugCentral uuid:ea5f0418-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idarubicin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:ea5f2880-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idarubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:ea5f4cd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idarubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:ea5f7182-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idebenone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:ea5f9aa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idebenone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:ea5fc330-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idebenone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ea5febc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idebenone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:ea60142a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:1417 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idoxuridine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:ea603dce-ac81-11ec-8b6b-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:1417 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idoxuridine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ea606650-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ea608ed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.41']} DrugCentral uuid:ea60b736-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ea60e01c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ea610894-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ea61312a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ea615ace-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:ea6183e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:ea61ac40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ea61d544-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ea61fede-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ea62276a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ea624fec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.99']} DrugCentral uuid:ea627d50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ea627d50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ea62b950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ea62b950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ea62b950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ea62f87a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00960 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate [NMDA] receptor subunit epsilon 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ea632106-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60490 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Unclassified (3-beta-hydroxysteroid-delta(8),delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.57']} DrugCentral uuid:ea634a6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:ea6372fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ea639b7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ea63c3ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:1419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ifenprodil targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:ea63ed66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ea6415b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ea643e42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:ea6466c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ea648fdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ea64b85e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:ea64e0ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ea650a34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ea6532ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ea655b4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ea6583e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:ea65ade0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ea65d98c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ea660204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ea662b80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:ea665448-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:ea667cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:1422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ea66a54c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:ea66cdce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:ea66f704-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:ea6720bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:ea67495c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ea6771fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:ea6799ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ea67c4b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ea67ed44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:ea6816de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ea683f6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:ea686800-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ea6890aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:ea68b9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:ea68e26c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:ea690aee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ea693366-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:ea695dbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ea69864a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ea69aed6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:ea69d762-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ea6a0048-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ea6a29ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ea6a5250-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ea6a7ad2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ea6aa3fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:ea6acc76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ea6af502-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:ea6b1d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ea6b49f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:ea6b72c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ea6b9b4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ea6bc446-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ea6becb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ea6c152c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ea6c3dcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ea6c66bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ea6c8f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ea6cb7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ea6ce074-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:ea6d0a54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ea6d342a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:ea6d5cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ea6d8542-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ea6dae32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ea6dd6c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ea6dff54-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:ea6e28d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ea6e51fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ea6e7a7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:ea6ea378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ea6ecd12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ea6ef7e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ea6f2064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:ea6f48c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ea6f717c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15046 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Lysine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ea6f99ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ea6fc28a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:ea6feaf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:ea701442-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:ea703d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ea70658c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ea708e72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:ea70b96a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ea70e1ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ea710a78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ea71330e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.97']} DrugCentral uuid:ea715bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:ea718462-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ea71acee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ea71d570-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:ea71fe88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ea7227f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:ea72507c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:ea727da4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ea727da4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ea72b558-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ea72b558-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ea72ecf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:ea72ecf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:ea7322ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05030 biolink:molecularly_interacts_with DrugCentral:1423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:ea734b4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imidapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ea7373d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem targets Enzyme (Penicillin-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ea739c5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem targets Enzyme (Penicillin-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ea73c59c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ea73ee32-ac81-11ec-8b6b-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ea742dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ea742dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ea742dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ea742dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ea742dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ea742dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ea742dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ea7493fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:ea74bcae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.284']} DrugCentral uuid:ea74e59e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ea750eca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.854']} DrugCentral uuid:ea7537b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.432']} DrugCentral uuid:ea756046-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:ea758a58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.825']} DrugCentral uuid:ea75b2f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:ea75db7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.495']} DrugCentral uuid:ea760410-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ea762e7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.412']} DrugCentral uuid:ea76588e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.614']} DrugCentral uuid:ea7680fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:ea76a9a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:ea76d282-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:ea76fb18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:ea7723ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.081']} DrugCentral uuid:ea774c44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.071']} DrugCentral uuid:ea777566-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:ea779df2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ea77c660-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ea77eef6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ea781854-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:ea7840d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:ea786a98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ea7893b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:ea78bc46-ac81-11ec-8b6b-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ea78e4dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34968 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ea790d5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:ea793680-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ea795f02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:ea79887e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ea79b114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:ea79db94-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:ea7a1d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ea7a1d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ea7a1d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ea7a1d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ea7a1d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ea7a1d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ea7a1d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ea7a9944-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ea7a9944-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ea7a9944-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ea7a9944-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ea7a9944-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7b2152-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ea7bed80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ea7bed80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ea7bed80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ea7c3dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ea7c3dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ea7c3dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ea7c3dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ea7c3dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ea7c9bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:ea7c9bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:ea7c9bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:ea7ce384-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ea7ce384-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ea7ce384-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ea7d2a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ea7d2a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ea7d2a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ea7d6976-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48545 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ea7d9478-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ea7dbd18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17405 biolink:molecularly_interacts_with DrugCentral:1427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imipramine targets Enzyme (Sphingomyelin phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ea7de5a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imiquimod targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:ea7e0fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imiquimod targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:ea7e3842-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imiquimod targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ea7e6100-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYK1 biolink:molecularly_interacts_with DrugCentral:1429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imiquimod is agonist of Membrane receptor (Toll-like receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:ea7e8996-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:1431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 incadronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ea7eb2c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8MTZ4 biolink:molecularly_interacts_with DrugCentral:1431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 incadronic acid targets Unclassified (Vacuolar-type proton translocating pyrophosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:ea7edb80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:1431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 incadronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:ea7f0402-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indalpine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ea7f2c8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ea7f574a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ea7f804e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:ea7fa8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:ea7fd18e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:ea7ffa9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ea80233c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51787 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Ion channel (Potassium voltage-gated channel subfamily KQT member 1) DrugCentral uuid:ea8047b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ea807044-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:ea80998e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:ea80c242-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ea80ebf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:ea81149a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.535']} DrugCentral uuid:ea813f88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:ea81681e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:ea8190b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indecainide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:ea81b562-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indenolol targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:ea81d9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indenolol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:ea81fe14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:ea822772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.222']} DrugCentral uuid:ea825008-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.733']} DrugCentral uuid:ea827920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ea82a238-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:ea82cac4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:ea82f49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ea831fe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:ea834850-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.27']} DrugCentral uuid:ea8370e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:ea8399e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:ea83c28a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1438 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:ea83eb34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indobufen targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:ea840f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indobufen targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:ea8434b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:ea845d4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:ea8485e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:ea84ae5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ea84d94a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:ea850492-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:ea852d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BPW9 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ea855582-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ea857e54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:ea85a6cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ea85cf3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:ea85f7a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.691']} DrugCentral uuid:ea8620d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:ea864a5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ea8672fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ea869c3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ea86c4d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ea86ee7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.19']} DrugCentral uuid:ea871700-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ea8743b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ea876c50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ea8794f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ea87bd86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ea87e66c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ea880ef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ea883784-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:ea8863ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ea8863ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ea889cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ea889cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ea88d478-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase (cyclooxygenase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ea88d478-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase (cyclooxygenase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ea8908c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29477 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ea893148-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:ea8959b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17516 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:ea89822e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ea89ab28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indomethacin targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:ea89d3d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ea89fd6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08659 biolink:molecularly_interacts_with DrugCentral:1442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoprofen targets Unclassified (Luciferin 4-monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ea8a25ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:ea8a5050-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:ea8a7aa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ea8aa33e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:ea8acbca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:ea8af4ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ea8b1d82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ea8b4618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ea8b6ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ea8b9f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ea8b9f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ea8b9f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ea8be672-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:ea8be672-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:ea8be672-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:ea8c2be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 intoplicine targets Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ea8c5454-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:1446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 intoplicine targets Enzyme (DNA topoisomerase I, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ea8c7cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:1446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 intoplicine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ea8ca562-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diiodohydroxyquinoline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.278']} DrugCentral uuid:ea8ccea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diiodohydroxyquinoline targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.724']} DrugCentral uuid:ea8cf72e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diiodohydroxyquinoline targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.609']} DrugCentral uuid:ea8d1f9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diiodohydroxyquinoline targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.804']} DrugCentral uuid:ea8d480a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diiodohydroxyquinoline targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.067']} DrugCentral uuid:ea8d70f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.279']} DrugCentral uuid:ea8d9a6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.439']} DrugCentral uuid:ea8dc2f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diiodohydroxyquinoline targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.043']} DrugCentral uuid:ea8dec74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.532']} DrugCentral uuid:ea8e171c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diiodohydroxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:ea8e3f8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:ea8e67f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:ea8e914c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipratropium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.292']} DrugCentral uuid:ea8eba5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.181']} DrugCentral uuid:ea8ee2dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:ea8f0b5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:ea8f3458-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:ea8f5ce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.74']} DrugCentral uuid:ea8f8570-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipratropium targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:ea8fadfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipriflavone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.531']} DrugCentral uuid:ea8fd7c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipriflavone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:ea90005e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1478 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iprindole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:ea9028f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1478 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iprindole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.899']} DrugCentral uuid:ea905176-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1478 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iprindole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:ea907b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1478 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iprindole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.185']} DrugCentral uuid:ea90a3ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1480 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iproniazid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ea90cc32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:1480 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iproniazid targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ea90f4c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1480 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iproniazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ea911dae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1480 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iproniazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:ea91464e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irbesartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ea916ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:1481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irbesartan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ea919946-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irbesartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ea91c614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irbesartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:ea91c614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irbesartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:ea9202e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:ea9202e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:ea9202e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:ea9242ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irbesartan is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ea926b78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:ea928ff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:ea92b880-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:ea92dd4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.336']} DrugCentral uuid:ea9305ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:ea932a36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:ea934e80-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:ea937464-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ea939dfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan is inhibitor of Enzyme (DNA topoisomerase 1) DrugCentral uuid:ea93c266-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.218']} DrugCentral uuid:ea93eafc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:ea94143c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:ea943cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ea946540-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ea948dc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ea94b6a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:ea94df16-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:1483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 irofulven targets Kinase (Serine/threonine-protein kinase Chk2) DrugCentral uuid:ea95045a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:1486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isepamicin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.87']} DrugCentral uuid:ea952cf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1490 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isocarboxazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:ea955248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1490 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isocarboxazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:ea9577b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoetarine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:ea95a04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.109']} DrugCentral uuid:ea95c8f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:ea95edfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:ea96126e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:ea9636ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:ea965b66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:ea968424-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:ea968424-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea96ebe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ea97a69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluostigmine targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ea97d004-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ea97f8ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.15']} DrugCentral uuid:ea982130-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:ea984b10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:1494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluostigmine targets Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ea987388-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q29550 biolink:molecularly_interacts_with DrugCentral:1494 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluostigmine targets Enzyme (Liver carboxylesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ea989c00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoniazid targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:ea98c46e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WIE4 biolink:molecularly_interacts_with DrugCentral:1497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoniazid targets Enzyme (Catalase-peroxidase) DrugCentral uuid:ea98ea02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:1497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoniazid is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:ea991496-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoniazid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ea993d04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoniazid targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ea99659a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WNX1 biolink:molecularly_interacts_with DrugCentral:1497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoniazid targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ea998eda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ea99b75c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:ea99dfd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ea9a086a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ea9a3178-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:ea9a59f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ea9a8286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.752']} DrugCentral uuid:ea9aaaf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ea9ad5ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ea9b0116-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ea9b29ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ea9b52ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9b7c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9ba468-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04274 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:ea9bce16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ea9bf710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ea9c1fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ea9c4846-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59533 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 38) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9c71b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59534 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 39) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9c9ada-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59535 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 40) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9cc370-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59536 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 41) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9cebfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59537 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 43) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9d1474-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59538 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 31) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9d3db4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59539 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 45) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9d664a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9d8eb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59541 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 30) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9db73a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59542 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 19) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9de016-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59543 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9e088e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59544 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 50) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9e311a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59551 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 60) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9e59b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTR8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 42) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9e8566-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYV7 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 16) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9eb11c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9ed99e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYV9 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 13) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9f02f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYW0 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9f2b6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYW1 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9f53ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYW2 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9f7c5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYW3 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9fa5d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYW4 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9fce58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYW5 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ea9ff6d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYW6 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:eaa01f34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYW7 biolink:molecularly_interacts_with DrugCentral:1499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:eaa04964-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1500 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isopropamide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:eaa06ee4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1500 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isopropamide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:eaa0934c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isosorbide dinitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:eaa0c358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:eaa0c358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:eaa0c358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:eaa0c358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:eaa10660-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1506 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isosorbide mononitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:eaa13676-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:eaa13676-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:eaa13676-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:eaa13676-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:eaa17a5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:eaa1a30e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:eaa1cbae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.628']} DrugCentral uuid:eaa1f44e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['8.229']} DrugCentral uuid:eaa21e92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08319 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets Enzyme (Alcohol dehydrogenase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:eaa247be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BPW9 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.523']} DrugCentral uuid:eaa2704a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets Enzyme (11-cis retinol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:eaa298d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14756 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets Enzyme (17-beta-hydroxysteroid dehydrogenase type 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:eaa2c234-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin is inhibitor of Nuclear hormone receptor (Retinoic acid receptor beta) DrugCentral uuid:eaa2e69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.597']} DrugCentral uuid:eaa30f1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.335']} DrugCentral uuid:eaa337aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40220 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:eaa360a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isotretinoin targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:eaa3893a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1509 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:eaa3b1bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1509 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:eaa3da34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isradipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:eaa4007c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isradipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:eaa425e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:eaa44e9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:eaa47728-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isradipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:eaa4a090-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:1511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isradipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:eaa4c944-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isradipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:eaa4f1e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JIS7 biolink:molecularly_interacts_with DrugCentral:1511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eaa51a84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01815 biolink:molecularly_interacts_with DrugCentral:1511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:eaa543f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eaa56c96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.046']} DrugCentral uuid:eaa59540-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['9.246']} DrugCentral uuid:eaa5bf5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:eaa5e824-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:eaa610ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eaa6395a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eaa662b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:eaa68b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:eaa6b3b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:eaa6dd6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:eaa7066e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:1513 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 itraconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:eaa74dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:eaa74dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:eaa74dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:eaa74dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:eaa74dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:eaa74dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:eaa74dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:eaa74dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:eaa74dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:eaa7c7ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:1519 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kanamycin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.678']} DrugCentral uuid:eaa7f07e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A6R0 biolink:molecularly_interacts_with DrugCentral:1519 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kanamycin targets Unclassified (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:eaa818f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29033 biolink:molecularly_interacts_with DrugCentral:1519 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kanamycin targets Unclassified (Gap junction beta-2 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:eaa84218-ac81-11ec-8b6b-0242ac110002 UniProtKB:C3TDZ2 biolink:molecularly_interacts_with DrugCentral:1520 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bekanamycin targets Enzyme (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:eaa86a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A6R0 biolink:molecularly_interacts_with DrugCentral:1520 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bekanamycin targets Unclassified (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:eaa89326-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:eaa8d37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:eaa8d37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:eaa8d37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:eaa8d37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:eaa8d37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:eaa8d37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:eaa8d37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:eaa95694-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:eaa95694-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:eaa95694-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:eaa95694-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:eaa95694-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:eaa95694-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:eaa95694-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:eaa9d114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:eaa9d114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:eaa9d114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:eaa9d114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:eaaa14b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eaaa3d2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:eaaa65ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki'} DrugCentral uuid:eaaa9022-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:eaaab91c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:eaaae18a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:eaab0a2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:eaab32a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eaab5c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:eaab84dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:eaabad86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:eaabd6d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:eaabff5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.701']} DrugCentral uuid:eaac27de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eaac5056-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.747']} DrugCentral uuid:eaac7932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:eaaca1a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:eaacca18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:eaacf286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:eaad1d06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:eaad47b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:eaad7044-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:eaad98c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.903']} DrugCentral uuid:eaadc210-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:eaadea9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:eaae140e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:eaae3cc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:eaae65bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.33']} DrugCentral uuid:eaae8e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eaaeb6fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:eaaee03c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eaaf0b48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:eaaf3b90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:eaaf3b90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:eaaf3b90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:eaaf8352-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:eaaf8352-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:eaaf8352-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:eaafc29a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eaafeb44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BRU6 biolink:molecularly_interacts_with DrugCentral:1524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketanserin targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:eab0139e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:eab03db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:eab06646-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.585']} DrugCentral uuid:eab08ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:eab0c3e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eab0c3e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eab0c3e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eab0c3e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eab119a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eab119a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eab119a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eab119a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eab165a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.821']} DrugCentral uuid:eab18e22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:eab1b762-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:eab1dfda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:eab208d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:eab2316a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:eab259ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:eab28282-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.084']} DrugCentral uuid:eab2ae88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.667']} DrugCentral uuid:eab2da0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.028']} DrugCentral uuid:eab3050e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:eab32e26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.729']} DrugCentral uuid:eab356a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:eab37b10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:eab3a3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:eab3cca0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:eab3f52c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:eab41e26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:eab446b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:eab47150-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:eab49d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eab4c84e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:eab4f0c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.665']} DrugCentral uuid:eab51ae2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'app Ki', 'has_quantitative_value': ['7.197']} DrugCentral uuid:eab54332-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:eab56bc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:eab59576-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:eab5bf60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:eab5e7ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.266']} DrugCentral uuid:eab6105a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.897']} DrugCentral uuid:eab63a4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.211']} DrugCentral uuid:eab66528-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:eab68dd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:eab6b64a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.66']} DrugCentral uuid:eab6df58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07973 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.506']} DrugCentral uuid:eab707d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08686 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 21) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:eab73034-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15150 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 11B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:eab758b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14137 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:eab7819c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09128 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 24A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:eab7a9f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18125 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 7A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:eab7d278-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q64654 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 51) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:eab7faf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11715 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 17A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:eab8264c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:eab850d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35084 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:eab87962-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:eab8a1e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole is inhibitor of Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:eab8cb06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoconazole is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.896']} DrugCentral uuid:eab8f37e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:eab91ce6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:eab945ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:eab96e80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:eab99afe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:eab99afe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:eab9cef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketorolac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:eab9fa58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketorolac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.72']} DrugCentral uuid:eaba2348-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketorolac targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:eaba4bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketorolac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.214']} DrugCentral uuid:eaba7438-ac81-11ec-8b6b-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketorolac targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:eaba9d6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:1529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketorolac targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:eabac5dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.361']} DrugCentral uuid:eabaee68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:eabb1762-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:eabb3bc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.839']} DrugCentral uuid:eabb6604-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.047']} DrugCentral uuid:eabb8ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:eabbb870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.076']} DrugCentral uuid:eabbe106-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:eabc09b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.489']} DrugCentral uuid:eabc323c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:eabc5b54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.509']} DrugCentral uuid:eabc83d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.391']} DrugCentral uuid:eabcac62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:eabcd4bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.016']} DrugCentral uuid:eabcfda2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.359']} DrugCentral uuid:eabd2714-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:eabd4fa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.075']} DrugCentral uuid:eabd782c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:eabda342-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.737']} DrugCentral uuid:eabdcbec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:eabdf4be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1530 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eabe1d54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.234']} DrugCentral uuid:eabe46d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:eabe6f70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.117']} DrugCentral uuid:eabe9810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.478']} DrugCentral uuid:eabec128-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.648']} DrugCentral uuid:eabee9be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:eabf1254-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.894']} DrugCentral uuid:eabf3acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:eabf64ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:eabf8f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.491']} DrugCentral uuid:eabfb7b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:eabfe030-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:eac00916-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47154 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets Enzyme (CAAX prenyl protease 1) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eac0317a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:1531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 labetalol targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:eac059d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacidipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.046']} DrugCentral uuid:eac0824c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacidipine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.245']} DrugCentral uuid:eac0ab46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacidipine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:eac0d3be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacidipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.642']} DrugCentral uuid:eac0fc36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacidipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:eac125a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacidipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:eac14f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacidipine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.771']} DrugCentral uuid:eac1797c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacidipine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:eac1a668-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:eac1a668-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:eac1d520-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00214 biolink:molecularly_interacts_with DrugCentral:1535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lactose targets Unclassified (Galectin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.21']} DrugCentral uuid:eac1fdac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00182 biolink:molecularly_interacts_with DrugCentral:1535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lactose targets Unclassified (Galectin-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eac22638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17931 biolink:molecularly_interacts_with DrugCentral:1535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lactose targets Unclassified (Galectin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.03']} DrugCentral uuid:eac24ec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:1539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamivudine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:eac275ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:1539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamivudine is inhibitor of Polyprotein (Protein P) DrugCentral uuid:eac29a5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1539 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamivudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:eac2c2fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:eac2eb68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.839']} DrugCentral uuid:eac3150c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:eac33974-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:eac36214-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:eac38a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:eac3b3a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:eac3d816-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:eac400a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.744']} DrugCentral uuid:eac42938-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:eac45282-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:eac47afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:eac4ab4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:eac4ab4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:eac4ab4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:eac4ed32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lamotrigine targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:eac515b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1545 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 landiolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:eac53a26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:1546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:eac562da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:1546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:eac58bf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:eac5b492-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:1546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eac5dd32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:1546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:eac605b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:1546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanreotide targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:eac62f1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:1546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eac657a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:1546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanreotide targets GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:eac6805c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:1546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:eac6a8e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30936 biolink:molecularly_interacts_with DrugCentral:1546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:eac6d52a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.275']} DrugCentral uuid:eac6ffb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.473']} DrugCentral uuid:eac72962-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:eac75306-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCT1 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole targets Enzyme (Phosphoethanolamine/phosphocholine phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:eac77b6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eac7a3f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:eac7d074-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:eac7d074-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:eac7ff54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:eac827d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:eac85062-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:1547 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lansoprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:eac878bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:eac89dd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:eac8c218-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:eac8eb8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eac91416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:eac93d74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:eac9660a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Transporter (Solute carrier organic anion transporter family member 1B1) DrugCentral uuid:eac98a7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eac9b2fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:eac9dbf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:eaca047a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:eaca2d24-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eaca55a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:eaca8210-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:eacaaa88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:eacad30a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:eacafc5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00750 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:eacb24ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75747 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:eacb4d6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:eacb75ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lapatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eacb9ede-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:1549 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arginine hydrochloride targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eacbc774-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5T6X5 biolink:molecularly_interacts_with DrugCentral:1549 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arginine hydrochloride is agonist of GPCR (G-protein coupled receptor family C group 6 member A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:eacbefe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75746 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Transporter (Calcium-binding mitochondrial carrier protein Aralar1) DrugCentral uuid:eacc1422-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17174 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Enzyme (Aspartate aminotransferase, cytoplasmic) DrugCentral uuid:eacc3a10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45381 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Enzyme (Aspartoacylase) DrugCentral uuid:eacc5e64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08243 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Enzyme (Asparagine synthetase [glutamine-hydrolyzing]) DrugCentral uuid:eacc82ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00966 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Enzyme (Argininosuccinate synthase) DrugCentral uuid:eacca748-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03154 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Enzyme (Aminoacylase-1) DrugCentral uuid:eacccd40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00505 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Enzyme (Aspartate aminotransferase, mitochondrial) DrugCentral uuid:eaccf27a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14868 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Enzyme (Aspartate--tRNA ligase, cytoplasmic) DrugCentral uuid:eacd16d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12797 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Enzyme (Aspartyl/asparaginyl beta-hydroxylase) DrugCentral uuid:eacd3b68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43003 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:eacd6502-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43004 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eacd8dac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43005 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:eacdb610-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UJS0 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Transporter (Calcium-binding mitochondrial carrier protein Aralar2) DrugCentral uuid:eacdf1a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:eacdf1a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:eacdf1a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:eacdf1a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:eacdf1a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:eacdf1a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:eacdf1a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:eace659c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35921 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eace8e32-ac81-11ec-8b6b-0242ac110002 UniProtKB:O59010 biolink:molecularly_interacts_with DrugCentral:1550 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aspartic acid targets Transporter (Glutamate transporter homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:eaceb722-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 latanoprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.757']} DrugCentral uuid:eacedf9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 latanoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.187']} DrugCentral uuid:eacf0830-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 latanoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eacf30da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:1551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 latanoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:eacf5a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leflunomide targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.287']} DrugCentral uuid:eacf82d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leflunomide targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.338']} DrugCentral uuid:eacfab6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leflunomide targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:eacfd40e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:1552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leflunomide is inhibitor of Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:eacffdb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leflunomide targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:ead0263e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leflunomide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.684']} DrugCentral uuid:ead04f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:1552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ead07896-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35435 biolink:molecularly_interacts_with DrugCentral:1552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ead0a12c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 letrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ead0c9ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 letrozole targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:ead0f23a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 letrozole targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ead11b66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1557 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leucine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ead143fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1559 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leuprorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:ead16c9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:1559 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 leuprorelin targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ead19546-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1560 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levallorphan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:ead1bf12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1560 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levallorphan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:ead1e776-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1560 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levallorphan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ead21cdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:ead21cdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:ead21cdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:ead21cdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:ead267dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N587 biolink:molecularly_interacts_with DrugCentral:1561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamisole targets Ion channel (Acetylcholine receptor subunit alpha-type unc-63) DrugCentral uuid:ead28c44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:1561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamisole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ead2b4f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96760 biolink:molecularly_interacts_with DrugCentral:1561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamisole is agonist of Ion channel (Nicotinic acetylcholine receptor alpha subunit) DrugCentral uuid:ead2d96a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamisole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.568']} DrugCentral uuid:ead302d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09487 biolink:molecularly_interacts_with DrugCentral:1561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamisole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:ead32b68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09923 biolink:molecularly_interacts_with DrugCentral:1561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamisole targets Enzyme (Intestinal-type alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:ead353ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:ead37c8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ead3a5de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:ead3ce6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:ead3f7be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead45358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ead50faa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levetiracetam targets Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:ead5341c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levetiracetam targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:ead5597e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levetiracetam targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:ead580b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02563 biolink:molecularly_interacts_with DrugCentral:1563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levetiracetam is inhibitor of Unclassified (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ead5a9ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L0J3 biolink:molecularly_interacts_with DrugCentral:1563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levetiracetam is modulator of Transporter (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ead5d250-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1564 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levocabastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:ead5f802-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1564 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levocabastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.279']} DrugCentral uuid:ead6208e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95665 biolink:molecularly_interacts_with DrugCentral:1564 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levocabastine is agonist of GPCR (Neurotensin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ead64a46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63384 biolink:molecularly_interacts_with DrugCentral:1564 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levocabastine targets GPCR (Neurotensin receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:ead672e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70310 biolink:molecularly_interacts_with DrugCentral:1564 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levocabastine is agonist of GPCR (Neurotensin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ead69bd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levocetirizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:ead6c58e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1567 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levodopa targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ead6ee1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1567 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levodopa targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.541']} DrugCentral uuid:ead71692-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1567 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levodopa targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:ead80002-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1567 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levodopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:ead82afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1567 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levodopa targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.646']} DrugCentral uuid:ead853ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1567 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levodopa is agonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:ead878ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1567 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levodopa is agonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:ead89d3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levofloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.04']} DrugCentral uuid:ead8c640-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levofloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:ead8eef4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levofloxacin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:ead91d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levofloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:ead91d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levofloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:ead94fc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ead94fc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ead97e78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y256 biolink:molecularly_interacts_with DrugCentral:1569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levofloxacin targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:ead9a772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomethadyl acetate is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:ead9cc02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomethadyl acetate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:ead9f538-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levonorgestrel targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.225']} DrugCentral uuid:eada1de2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levonorgestrel targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:eada470e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levonorgestrel targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:eada6b8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levonorgestrel is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['12.796']} DrugCentral uuid:eada9402-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levonorgestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.91']} DrugCentral uuid:eadabc98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levonorgestrel targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:eadae678-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levonorgestrel targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.339']} DrugCentral uuid:eadb0f2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:eadb37b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:eadb6062-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:eadb8b0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:eadbb38c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:eadbdc40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:eadc04fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:eadc2e16-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:eadc56d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:eadc7f88-ac81-11ec-8b6b-0242ac110002 UniProtKB:O55242 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:eadcc272-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eadcc272-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eadcc272-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eadcc272-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eadcc272-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eadcc272-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eadcc272-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eadd463e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eadd463e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eadd463e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eadd463e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eadd463e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eadd463e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eadd463e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eaddbd9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:eaddbd9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:eaddbd9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:eaddbd9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:eade1168-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:eade1168-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:eade1168-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:eade5074-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levorphanol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:eade7928-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1575 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosalbutamol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:eadea5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosimendan targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) DrugCentral uuid:eadecc48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosimendan targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) DrugCentral uuid:eadef0d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15842 biolink:molecularly_interacts_with DrugCentral:1576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosimendan targets Ion channel (ATP-sensitive inward rectifier potassium channel 8) DrugCentral uuid:eadf1568-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63316 biolink:molecularly_interacts_with DrugCentral:1576 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosimendan is opener of Cytosolic other (Troponin C, slow skeletal and cardiac muscles) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.155']} DrugCentral uuid:eadf3e62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:eadf66ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:eadf8f84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:eadfb928-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:eadfe1aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:eae00a40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eae04258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:eae04258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:eae04258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:eae04258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:eae04258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:eae0a2d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:eae0a2d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:eae0a2d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:eae0e9ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:eae0e9ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:eae0e9ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:eae12a88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:eae15328-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:eae177b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:eae1a0a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:eae1c95c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:eae1f1b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.296']} DrugCentral uuid:eae21a38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:eae24094-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.559']} DrugCentral uuid:eae270d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:eae270d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:eae270d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:eae2b7b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:eae2b7b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:eae2b7b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:eae2f75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:eae31fe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:1579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:eae3487c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1580 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidoflazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:eae3716c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:1580 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidoflazine targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:eae3a1be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:eae3a1be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:eae3a1be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:eae3e0fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1581 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 limaprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) DrugCentral uuid:eae4071c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:1582 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lincomycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:eae42d3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:eae455be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:eae47f3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75NA5 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:eae4a82a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24046 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:eae4d872-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:eae4d872-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:eae4d872-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:eae51f3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:eae51f3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:eae51f3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:eae560da-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:eae560da-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:eae560da-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:eae5a0a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:eae5a0a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:eae5a0a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:eae5ebe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:eae5ebe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:eae5ebe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:eae62af6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eae6535a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:eae67c72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:eae6a4ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31040 biolink:molecularly_interacts_with DrugCentral:1584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linezolid targets Enzyme (Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:eae6cd80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine is agonist of Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.24']} DrugCentral uuid:eae6f63e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine is agonist of Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:eae71f42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:eae747ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:eae77050-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:eae799ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eae7c5fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae82b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eae93868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eaea0ef0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1587 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisinopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:eaea37f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1587 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisinopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:eaea60a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.491']} DrugCentral uuid:eaea8948-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:eaeab256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:eaeadaf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:eaeb03a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.936']} DrugCentral uuid:eaeb2c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:eaeb5652-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.061']} DrugCentral uuid:eaeb81f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eaebadaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.259']} DrugCentral uuid:eaebd870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eaec0174-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.625']} DrugCentral uuid:eaec29f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:eaec5264-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:eaec7adc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:eaeca4bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:eaeccd52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eaecf5d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:eaed1e6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.203']} DrugCentral uuid:eaed4ae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:eaed773e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eaed9fde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.037']} DrugCentral uuid:eaedc8d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.78']} DrugCentral uuid:eaedf178-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:eaee1a18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.338']} DrugCentral uuid:eaee42b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:eaee6bbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:eaee9448-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.33']} DrugCentral uuid:eaeebcd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:eaeee56a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eaef10b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisuride is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.489']} DrugCentral uuid:eaef3c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:eaef66a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:eaef8f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.268']} DrugCentral uuid:eaefb81e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:eaefe08c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eaf00904-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:eaf031fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.444']} DrugCentral uuid:eaf05a6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:eaf082d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.481']} DrugCentral uuid:eaf0ac4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.886']} DrugCentral uuid:eaf0d636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.468']} DrugCentral uuid:eaf0fecc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:eaf12758-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:eaf15002-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:eaf178fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:eaf1a192-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:eaf1d1ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eaf1d1ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eaf1d1ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eaf218fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:eaf218fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:eaf218fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:eaf2584e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lofexidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:eaf280bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43700 biolink:molecularly_interacts_with DrugCentral:1594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lomefloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eaf2aed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lomefloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:eaf2aed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1594 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lomefloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:eaf2de5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1595 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lomerizine targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:eaf306f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:1597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lonazolac targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:eaf32f8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:eaf358a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:eaf3812e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:eaf3a9b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) DrugCentral uuid:eaf3cdf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:eaf3f78a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.932']} DrugCentral uuid:eaf4200c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:eaf4499c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.343']} DrugCentral uuid:eaf47228-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:eaf49dca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.519']} DrugCentral uuid:eaf4c642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:eaf4eea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) DrugCentral uuid:eaf51390-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:eaf53c1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.599']} DrugCentral uuid:eaf564a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:eaf59504-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:eaf59504-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:eaf59504-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:eaf5cd8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:eaf5f60c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.345']} DrugCentral uuid:eaf61ea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) DrugCentral uuid:eaf6430a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) DrugCentral uuid:eaf669d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) DrugCentral uuid:eaf68e28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:eaf6b6be-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:eaf6df40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:eaf70844-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:eaf730c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:eaf7592a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:eaf781f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eaf7aa88-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:eaf7dada-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:eaf7dada-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:eaf7dada-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:eaf81ac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:eaf84484-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:1599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loperamide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:eaf86e32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lopinavir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:eaf896be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lopinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:eaf8bfb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lopinavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:eaf8e43e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lopinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:eaf90cde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80W54 biolink:molecularly_interacts_with DrugCentral:1601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lopinavir targets Enzyme (CAAX prenyl protease 1 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:eaf93588-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lopinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eaf95e5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lopinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.59']} DrugCentral uuid:eaf98704-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lopinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.54']} DrugCentral uuid:eaf9b74c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:eaf9b74c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:eaf9b74c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:eaf9f8ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:eaf9f8ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:eaf9f8ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:eafa3942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:eafa3942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:eafa3942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:eafa7970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eafa7970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eafa7970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eafab1d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1603 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loracarbef targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:eafaed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eafaed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eafaed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eafaed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eafaed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eafaed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eafaed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eafb4e4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:eafb76cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:eafb9f8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:eafbc96a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:eafbf232-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:eafc1aa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:eafc432c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:eafc6c12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:eafc9480-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:eafcbe56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:eafce6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2J7 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets Transporter (Sodium-dependent neutral amino acid transporter B(0)AT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:eafd0fdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loratadine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:eafd385e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1606 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorazepam targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:eafd68e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:eafd68e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:eafd68e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:eafda988-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorcainide targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:eafdcfee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:eafdf438-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:eafe188c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:eafe3d8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:eafe61e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.498']} DrugCentral uuid:eafe8a74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:eafeb300-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:eafedc18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:eaff04a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:eaff2e0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:eaff5698-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:eaff7fe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:eaffa86e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:eaffd10e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34976 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:eafff9a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WV26 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:eb0026ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:eb0026ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:eb006646-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:eb006646-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:eb006646-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:eb006646-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:eb00b56a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:eb00b56a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:eb00f0fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:eb00f0fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:eb00f0fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:eb0133f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:eb0133f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:eb016b9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCN6 biolink:molecularly_interacts_with DrugCentral:1610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 losartan targets Unclassified (Platelet glycoprotein VI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:eb019444-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loteprednol etabonate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:eb01b9c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.061']} DrugCentral uuid:eb01e304-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:eb020b90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.807']} DrugCentral uuid:eb023412-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eb025c80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.67']} DrugCentral uuid:eb02864c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eb02aec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets GPCR (Hydroxycarboxylic acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:eb02d750-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:eb02ffd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eb032930-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:eb0351a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:eb037a20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.697']} DrugCentral uuid:eb03a2b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:eb03cbce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:eb03f446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01237 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:eb041cbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eb044554-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20701 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Adhesion (Leukocyte adhesion glycoprotein LFA-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:eb046e30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95214 biolink:molecularly_interacts_with DrugCentral:1612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lovastatin targets Enzyme (Acyl-CoA:cholesterol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:eb04969e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.268']} DrugCentral uuid:eb04bf3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:eb04e7ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:eb051128-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.244']} DrugCentral uuid:eb0539be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:eb056268-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:eb058b8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:eb05b416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:eb05dc98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:eb06051a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:eb062e14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:eb06566e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:eb067fd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:eb06a86c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.682']} DrugCentral uuid:eb06d27e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.297']} DrugCentral uuid:eb06fb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:eb0723f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.376']} DrugCentral uuid:eb074cf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:eb077634-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.087']} DrugCentral uuid:eb079eb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.829']} DrugCentral uuid:eb07c864-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.411']} DrugCentral uuid:eb07f0fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:eb081a08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:eb0842c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:eb086b66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:eb0893f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.276']} DrugCentral uuid:eb08c03e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:eb08ebe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.854']} DrugCentral uuid:eb0914c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:eb093de8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5JUK3 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:eb096660-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:eb098ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:eb09b750-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:eb09e04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eb0a08b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eb0a313a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:eb0a61aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:eb0a61aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:eb0a61aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:eb0aa78c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:1614 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxiglumide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:eb0ad252-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:1614 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxiglumide is antagonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:eb0afae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1615 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:eb0b2432-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1615 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loxoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:eb0b4c96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lucanthone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eb0b750e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1617 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumefantrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:eb0b9d72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumiracoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:eb0bc676-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumiracoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:eb0bef02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumiracoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:eb0c1784-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:eb0c4010-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:eb0c6978-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.979']} DrugCentral uuid:eb0c91c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.856']} DrugCentral uuid:eb0cba68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.12']} DrugCentral uuid:eb0ce39e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:eb0d0c2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eb0d34c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:eb0d5d4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:eb0d861e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:eb0dafcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:eb0dd8b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.81']} DrugCentral uuid:eb0e0152-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:eb0e2c72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:eb0e5940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:eb0e8258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:eb0eaaee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eb0ed442-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:eb0efcd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eb0f256e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:eb0f4e0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:eb0f76d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eb0fa732-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eb0fa732-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eb0fa732-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eb0fe666-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1622 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lysine targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:eb101276-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:eb103b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:eb1063b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:eb108cf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:eb10b596-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:eb10de2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:eb11029e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:eb112bac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:eb115438-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:eb117c9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:eb11a500-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:eb11ceae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:eb11f71c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:eb121f8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:eb1248e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:eb127228-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:eb129a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:eb12c32c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:eb12ebcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:eb1314da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:eb133d7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:eb136606-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:eb138fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:eb13bb88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:eb13e4b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:eb140d40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:eb143658-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:eb145ef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:eb14878e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:eb14b02e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eb14d93c-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mafenide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:eb1501aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:1626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 malathion targets GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.538']} DrugCentral uuid:eb152a4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:A2PZ98 biolink:molecularly_interacts_with DrugCentral:1626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 malathion is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:eb154ea8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 manidipine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:eb157cde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 manidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:eb157cde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 manidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:eb15ab14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.308']} DrugCentral uuid:eb15d3a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:eb15fc2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.165']} DrugCentral uuid:eb162576-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.364']} DrugCentral uuid:eb164ed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:eb16777e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.27']} DrugCentral uuid:eb16a00a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:eb16c8fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:eb16f190-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:eb171a3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:eb1743c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.854']} DrugCentral uuid:eb176c42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.876']} DrugCentral uuid:eb1794c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.298']} DrugCentral uuid:eb17bd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.367']} DrugCentral uuid:eb17e65e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.777']} DrugCentral uuid:eb180efe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.406']} DrugCentral uuid:eb18378a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:eb186016-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:eb18891a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:eb18b192-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:eb18da28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.939']} DrugCentral uuid:eb1902aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:eb192dac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.355']} DrugCentral uuid:eb19589a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:eb198234-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:eb19aac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:eb19cfdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:eb19f854-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:eb1a216c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:eb1a4ad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:1634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maprotiline is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:eb1a73ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:1635 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maraviroc is antagonist of GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eb1a9c64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51682 biolink:molecularly_interacts_with DrugCentral:1635 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maraviroc targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:eb1ac4e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1635 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maraviroc targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:eb1aee9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61813 biolink:molecularly_interacts_with DrugCentral:1635 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maraviroc targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:eb1b170c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:eb1b3f8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:eb1b6806-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:eb1b911e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:eb1bb9aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eb1be236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:eb1c0ac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:eb1c33b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:eb1c5c2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:eb1c8542-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:eb1cadba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:eb1cd920-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:eb1d04f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:eb1d2dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:eb1d563e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:eb1d7f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eb1da7ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:eb1dd03c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BEG3 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:eb1df90e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48999 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:eb1e2578-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:eb1e2578-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:eb1e5a84-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15296 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase, type II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eb1e8310-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:eb1eb3a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:eb1edc20-ac81-11ec-8b6b-0242ac110002 UniProtKB:K4CF70 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Enzyme (Fatty acid hydroperoxide lyase, chloroplastic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eb1f04a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 masoprocol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:eb1f2d6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:1638 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maxacalcitol targets Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:eb1f5704-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:1638 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maxacalcitol is agonist of Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:eb1f7f86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mazindol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:eb1fa8a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eb1fd1c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:eb1ffa4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mazindol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:eb20230a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:eb204baa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mazindol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:eb207648-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mazindol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:eb209fb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mazindol targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eb20c832-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1640 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mazindol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:eb20f08c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:eb211972-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eb2141ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BJF5 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole targets Kinase (Calmodulin-domain protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:eb217228-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:eb217228-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:eb217228-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:eb21c1d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:eb21c1d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:eb21c1d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:eb21c1d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:eb21c1d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:eb21c1d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:eb21c1d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:eb2222ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1643 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebhydrolin is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.119']} DrugCentral uuid:eb224cca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1643 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebhydrolin targets GPCR (Histamine H4 receptor) DrugCentral uuid:eb22713c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1643 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebhydrolin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:eb2299aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1643 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebhydrolin targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:eb22c24a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.161']} DrugCentral uuid:eb22eb3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:eb2317b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:eb2317b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:eb234f6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.602']} DrugCentral uuid:eb234f6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.602']} DrugCentral uuid:eb2387ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine is negative allosteric modulator of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:eb2387ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine is negative allosteric modulator of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:eb23bf88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:eb23bf88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:eb23f76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:eb23f76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:eb2439fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eb2439fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eb2439fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eb2439fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eb248436-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine is blocker of Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:eb24adf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:eb24d684-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:eb24fefc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eb252788-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:1648 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecillinam is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.035']} DrugCentral uuid:eb255078-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1649 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclozine is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:eb2578fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1649 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclozine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:eb259d58-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35627 biolink:molecularly_interacts_with DrugCentral:1649 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclozine is agonist of Nuclear hormone receptor (Constitutive androstane receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eb25c60c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:1649 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclozine targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:eb25f05a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eb261904-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:eb264168-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eb2669c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:eb2692d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:eb26bb5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:eb26e3fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:eb270c88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:eb273564-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:eb275dfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:eb2786a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.503']} DrugCentral uuid:eb27af26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eb27da78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eb2802fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:eb282f46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:eb282f46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meclofenamic acid targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb289cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:eb297932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:eb297932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:eb297932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:eb29c36a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eb29c36a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eb29c36a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eb2a0a28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:eb2a0a28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:eb2a0a28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:eb2a5172-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:eb2a5172-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:eb2a5172-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:eb2a9196-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxalol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'pA2', 'has_quantitative_value': ['7.82']} DrugCentral uuid:eb2aba40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxalol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'pA2', 'has_quantitative_value': ['6.08']} DrugCentral uuid:eb2ae3a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.561']} DrugCentral uuid:eb2b0c5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:eb2b34f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eb2b5d60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:eb2b88bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.59']} DrugCentral uuid:eb2bb148-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:eb2bd9ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:eb2c02c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:eb2c2bd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:eb2c5440-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:eb2c7cea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:eb2ca620-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.032']} DrugCentral uuid:eb2cceb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:eb2cfc38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:eb2cfc38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:eb2d302c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1662 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 medrysone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:eb2d57c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:eb2d8090-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:eb2da8fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:eb2dd144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:eb2dfa34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:eb2e23a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:eb2e4c50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:eb2e75a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:eb2e9e26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:eb2ec694-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:eb2eef02-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:eb2f1914-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:eb2f427c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefenamic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:eb2f6aea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1665 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefloquine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:eb2f936c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1665 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefloquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:eb2fbc2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1665 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefloquine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:eb2fe0b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1665 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefloquine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:eb300932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1665 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefloquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:eb302d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1665 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefloquine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eb3056c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P90584 biolink:molecularly_interacts_with DrugCentral:1665 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefloquine targets Unclassified (Protein kinase Pfmrk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eb307f48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 megestrol acetate targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:eb30a3a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 megestrol acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.057']} DrugCentral uuid:eb30cc50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 megestrol acetate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:eb30f298-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 megestrol acetate targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:eb311b56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 megestrol acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:eb3143d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 megestrol acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.842']} DrugCentral uuid:eb316c6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1670 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meglutol targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:eb319568-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:eb31be08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.56']} DrugCentral uuid:eb31e69e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:eb320f98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:eb3239aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35398 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets Nuclear hormone receptor (Nuclear receptor ROR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:eb326236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:eb328aae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:eb32b47a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:eb32de00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:eb330e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:eb330e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:eb330e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:eb334d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:eb337680-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melatonin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:eb339f34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1676 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meloxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:eb33c7c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1676 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:eb33f10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1676 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:eb3419b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1676 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eb344222-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1676 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:eb346a7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:eb3493c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:eb34bc5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:eb34e0c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:eb350946-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.717']} DrugCentral uuid:eb353222-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:eb355ab8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:eb35833a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.063']} DrugCentral uuid:eb35aba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:eb35d4d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:eb35fd60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.357']} DrugCentral uuid:eb3626c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.469']} DrugCentral uuid:eb364f5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:eb36747a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:eb369d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:1678 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 melphalan targets Transporter (L-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:eb36c5ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1679 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 memantine targets Ion channel (5-hydroxytryptamine receptor 3A) DrugCentral uuid:eb36ea36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1679 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:eb370f02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05586 biolink:molecularly_interacts_with DrugCentral:1679 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:eb37378e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1679 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 memantine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:eb375ff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:1679 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 memantine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:eb378c98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1679 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:eb378c98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1679 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:eb37c550-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1679 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:eb37c550-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1679 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:eb37f9bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:eb382220-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eb384d36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:eb3875d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:eb389e6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eb38c702-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30305 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (M-phase inducer phosphatase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:eb38efe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:eb39186a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30307 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Dual specificity phosphatase Cdc25C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:eb3940f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15374 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Ubiquitin carboxyl-terminal hydrolase isozyme L3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:eb39696e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:eb3992ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q64346 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Dual specificity protein phosphatase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:eb39bb3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28563 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Dual specificity protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:eb39e4ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (M-phase inducer phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:eb3a0e82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:eb3a3830-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1684 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menadione sodium bisulfite targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:eb3a60bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1685 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 menatetrenone targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:eb3a8916-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:eb3ab1fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.119']} DrugCentral uuid:eb3ada88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:eb3b031e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:eb3b2bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.485']} DrugCentral uuid:eb3b54f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:eb3b7d94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.069']} DrugCentral uuid:eb3ba634-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.742']} DrugCentral uuid:eb3bcec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.167']} DrugCentral uuid:eb3bfa12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.504']} DrugCentral uuid:eb3c25a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:eb3c5070-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:eb3c794c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:eb3ca1d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:eb3cca6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:eb3cf2e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:eb3d1c26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:eb3d453e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.411']} DrugCentral uuid:eb3d6da2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:eb3d9638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:eb3dbf96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UDY8 biolink:molecularly_interacts_with DrugCentral:1688 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pecazine targets Enzyme (Mucosa-associated lymphoid tissue lymphoma translocation protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:eb3de8f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1689 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepenzolate is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:eb3e0d5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1689 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepenzolate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:eb3e361a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1689 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepenzolate is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:eb3e605e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1689 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepenzolate targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:eb3e88fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:eb3eb1b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:eb3eda34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:eb3eff1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.625']} DrugCentral uuid:eb3f27aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:eb3f4c12-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:eb3f749e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:eb3f9ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:eb3fc778-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:eb3ffb80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:eb3ffb80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:eb3ffb80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:eb3ffb80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:eb4051de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eb4051de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eb4051de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eb4051de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eb409c0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pethidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:eb40c52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1694 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephentermine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:eb410c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eb410c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eb410c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eb410c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eb410c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eb410c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eb410c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eb410c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eb410c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eb410c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eb4193d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb4193d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb4193d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb41cbe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:eb41f05c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:eb4215be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:eb423a30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:eb425eac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:eb42844a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:1700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:eb42a9de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1700 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:eb42ce64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprednisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:eb42f2b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.821']} DrugCentral uuid:eb4323a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:eb4323a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:eb4323a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:eb436892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:eb436892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:eb436892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:eb43ac44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:eb43ac44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:eb43ac44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:eb43eca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb43eca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb43eca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb4424c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meproscillarin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:eb444a32-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meptazinol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:eb447340-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:1706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meptazinol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:eb449bd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:1706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meptazinol targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:eb44c46c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meptazinol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:eb44ed02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meptazinol is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.06']} DrugCentral uuid:eb4516a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mequitazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.237']} DrugCentral uuid:eb453f50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:eb4567f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:eb459090-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.276']} DrugCentral uuid:eb45b980-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.955']} DrugCentral uuid:eb45e220-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:eb460aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mequitazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:eb463324-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mequitazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:eb465c64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q389T8 biolink:molecularly_interacts_with DrugCentral:1707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mequitazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:eb46850e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mercaptopurine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.789']} DrugCentral uuid:eb46ad7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:1708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mercaptopurine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:eb46d1ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mercaptopurine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:eb46f84a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:1708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mercaptopurine targets Enzyme (Purine nucleoside phosphorylase) DrugCentral uuid:eb471cc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06203 biolink:molecularly_interacts_with DrugCentral:1708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mercaptopurine is inhibitor of Enzyme (Amidophosphoribosyltransferase) DrugCentral uuid:eb474124-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51580 biolink:molecularly_interacts_with DrugCentral:1708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mercaptopurine targets Enzyme (Thiopurine S-methyltransferase) DrugCentral uuid:eb4766a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:1708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mercaptopurine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.1']} DrugCentral uuid:eb478f94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:1709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:eb47b3fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:eb47d86e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:1709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meropenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:eb47fcd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:eb482206-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meropenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:eb484682-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meropenem is inhibitor of Enzyme (D-alanyl-D-alanine carboxypeptidase DacB) DrugCentral uuid:eb486bee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:1709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meropenem targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:eb489466-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9K2N0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meropenem targets Unclassified (Beta-lactamase class B VIM-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eb48bdf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:C7C422 biolink:molecularly_interacts_with DrugCentral:1709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meropenem targets Enzyme (Beta-lactamase NDM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eb48e678-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XEC0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meropenem targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:eb490f18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1710 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesalazine is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:eb4937ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1710 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesalazine is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:eb495c98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1710 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:eb498196-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1710 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesalazine is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:eb49a5fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:1710 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesalazine targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:eb49ce94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1710 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesalazine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eb49f7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1710 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesalazine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eb4a2060-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WU19 biolink:molecularly_interacts_with DrugCentral:1710 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesalazine targets Enzyme (Hydroxyacid oxidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eb4a48ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:eb4a71a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.724']} DrugCentral uuid:eb4a9bc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:eb4ac466-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:eb4aed06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.125']} DrugCentral uuid:eb4b159c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.804']} DrugCentral uuid:eb4b3ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:eb4b6736-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:eb4b8fae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.744']} DrugCentral uuid:eb4bb830-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:eb4be15c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:eb4c09de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:eb4c3256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:eb4c5bf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:eb4c87c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesoridazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.041']} DrugCentral uuid:eb4cb06e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1714 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mestranol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.647']} DrugCentral uuid:eb4cd8f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1714 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mestranol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:eb4d01e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1714 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mestranol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:eb4d2a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1714 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mestranol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.282']} DrugCentral uuid:eb4d5442-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1714 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mestranol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:eb4d7ce2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1714 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mestranol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.958']} DrugCentral uuid:eb4da67c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orciprenaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eb4dcf1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orciprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:eb4df7da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1721 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metaraminol is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:eb4e1c4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:eb4e47b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:eb4e72be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:eb4e9b5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:eb4ec408-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.504']} DrugCentral uuid:eb4eed02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:eb4f1598-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:eb4f3e24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eb4f6764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:eb4f9090-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:eb4fb908-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:eb4fe19e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:eb500b6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.124']} DrugCentral uuid:eb5036e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.583']} DrugCentral uuid:eb505f70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:eb508932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:eb50b218-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:eb50dac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:eb510376-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:eb512c2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:eb51556a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:eb517dec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:eb51a68c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.872']} DrugCentral uuid:eb51cf18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:eb51fb50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:eb522486-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:eb524d26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.867']} DrugCentral uuid:eb52762a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:eb529ec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eb52c76a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:eb52efe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:eb531922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:eb5342d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:eb536b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:eb539fc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb539fc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb539fc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb539fc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb53f748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:eb53f748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:eb53f748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:eb543794-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y478 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin targets Kinase (5'-AMP-activated protein kinase subunit beta-1) DrugCentral uuid:eb545c4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:eb5484ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.697']} DrugCentral uuid:eb54ad3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.401']} DrugCentral uuid:eb54d5b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['2.499']} DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb55be84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:eb57c792-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:eb57f0fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:eb58199a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:eb583e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:eb586698-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:eb5890c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:eb58b940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:eb58e1cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:1726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:eb590a6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43351 biolink:molecularly_interacts_with DrugCentral:1727 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metacycline targets Nuclear other (DNA repair protein RAD52 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:eb593456-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methadone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.78']} DrugCentral uuid:eb595fc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methadone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:eb598b18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methadone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:eb59b386-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methadone targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:eb59d8ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:1728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methadone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:eb59fd1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methadone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eb5a31a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:eb5a31a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:eb5a31a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:eb5a31a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:eb5a7c94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylmethadol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:eb5aa520-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetylmethadol is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:eb5ac988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.383']} DrugCentral uuid:eb5af228-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:eb5b1da2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.133']} DrugCentral uuid:eb5b462e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:eb5b6e92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:eb5b9728-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:eb5bc068-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:eb5be91c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.611']} DrugCentral uuid:eb5c11bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:eb5c3b92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:eb5c641e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:eb5c8dc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.88']} DrugCentral uuid:eb5cb630-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:1732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:eb5cf046-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:eb5cf046-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:eb5cf046-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:eb5cf046-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:eb5cf046-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:eb5d3c04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:eb5d649a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:eb5d8e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:eb5db6ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:eb5ddfe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:eb5e088c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.409']} DrugCentral uuid:eb5e31b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.843']} DrugCentral uuid:eb5e5a4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:eb5e82e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:eb5eade6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.939']} DrugCentral uuid:eb5ed8b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.228']} DrugCentral uuid:eb5f0156-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:eb5f29ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:eb5f52f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methapyrilene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:eb5f834c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:eb5f834c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:eb5f834c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:eb5fcb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:eb5fcb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:eb5fcb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:eb6012b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:eb6012b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:eb6012b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:eb60598e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:eb60598e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:eb60598e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:eb60a326-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:eb60a326-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:eb60a326-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:eb60ea16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:eb60ea16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:eb60ea16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:eb61317e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:eb61317e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:eb61317e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:eb617490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:eb617490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:eb61affa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:eb61affa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:eb61affa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:eb61f852-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eb61f852-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eb61f852-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb62726e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb632cb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:eb635576-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:eb637e34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:eb63a738-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:eb63cfd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:eb63f86e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:eb642118-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:eb644e0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:eb6477bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:eb64a052-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:eb64c956-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:eb64f200-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:eb651a8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:eb65432c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:eb656c1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:eb6594b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:eb65bd34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:eb65e5ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:eb660f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:eb66380e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:eb6660b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:eb668962-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:eb66b25c-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:eb66dafc-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:eb6704a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:eb672d36-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:eb67564e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:eb677eee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:eb67a78e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb67fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:eb68a60c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eb68a60c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eb68da00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:eb6902aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:eb692bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methazolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:eb69546c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1742 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methdilazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:eb6978ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07944 biolink:molecularly_interacts_with DrugCentral:1744 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meticillin targets Enzyme (Beta-lactam-inducible penicillin-binding protein) DrugCentral uuid:eb699d32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18843 biolink:molecularly_interacts_with DrugCentral:1744 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meticillin targets Enzyme (NH(3)-dependent NAD(+) synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:eb69d824-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:eb69d824-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:eb69d824-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:eb69d824-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:eb69d824-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:eb6a2482-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:1745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamazole is inhibitor of Enzyme (Thyroid peroxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:eb6a4d54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:1745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:eb6a75cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22079 biolink:molecularly_interacts_with DrugCentral:1745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:eb6a9e26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15101 biolink:molecularly_interacts_with DrugCentral:1745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamazole targets Enzyme (Dopamine beta-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:eb6ac6c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1747 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methocarbamol is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eb6aef98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1748 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methohexital targets Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:eb6b1bc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb6b1bc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb6b1bc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb6b59d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1748 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methohexital targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:eb6b59d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1748 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methohexital targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:eb6b8926-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:eb6bad7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:eb6bd1ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:eb6bf654-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:eb6c1b3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:eb6c43ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:eb6c6850-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:eb6c90c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:eb6cb5e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:eb6cde52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:eb6d06b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:eb6d2f38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:eb6d590e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:eb6d84e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:eb6db07a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.14']} DrugCentral uuid:eb6dd906-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:eb6e01ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:eb6e2a5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.89']} DrugCentral uuid:eb6e5304-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:eb6e7b68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:eb6ea49e-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.68']} DrugCentral uuid:eb6ecd16-ac81-11ec-8b6b-0242ac110002 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:eb6ef58e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:eb6f1eec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:eb6f48ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WNX1 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.08']} DrugCentral uuid:eb6f713a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q81R22 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.91']} DrugCentral uuid:eb6f99c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:eb6fc2ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00380 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:eb6feb2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:eb7013ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:eb703c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:eb7065d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:1751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methotrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:eb708e8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1752 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomepromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.237']} DrugCentral uuid:eb70b874-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1752 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomepromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:eb70e11e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1753 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxamine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:eb710aae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1753 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxamine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:eb71333a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1753 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxamine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:eb715be4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1753 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxamine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eb718c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eb718c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eb718c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eb71cbc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is agonist of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb7229d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eb72e540-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methscopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:eb730de0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:eb733694-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methscopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:eb735f2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.01']} DrugCentral uuid:eb738824-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:eb73b0c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:eb73e10c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:eb73e10c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:eb73e10c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:eb7419a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylclothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:eb743df0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metildigoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:eb74624e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1762 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyldopa is agonist of GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:eb7487d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:1762 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyldopa targets Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:eb74add0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1762 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyldopa targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.282']} DrugCentral uuid:eb74d6ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1762 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyldopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.286']} DrugCentral uuid:eb74ff1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1762 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyldopa targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.672']} DrugCentral uuid:eb75279c-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:1762 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyldopa targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:eb75505a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylthioninium chloride targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:eb7578d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylthioninium chloride targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:eb75a168-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylthioninium chloride targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:eb75cad0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:1763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylthioninium chloride targets Enzyme (Thioredoxin reductase 1, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:eb75f3fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15770 biolink:molecularly_interacts_with DrugCentral:1763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylthioninium chloride targets Enzyme (Glutathione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:eb761c7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylthioninium chloride targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:eb764500-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:1763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylthioninium chloride targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:eb766d82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylthioninium chloride targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:eb769a00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:eb76c2c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:eb76eb54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.225']} DrugCentral uuid:eb771462-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.633']} DrugCentral uuid:eb773cee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:eb776584-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine is partial agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eb778e24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eb77b75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.928']} DrugCentral uuid:eb77dfe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.678']} DrugCentral uuid:eb780890-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:eb78311c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:eb785afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:eb788388-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:eb78ac14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.033']} DrugCentral uuid:eb78d496-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:eb78fd5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:eb7925d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1764 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:eb794e62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:eb7976ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eb79a006-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.93']} DrugCentral uuid:eb79c98c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:eb79f22c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:eb7a1aa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:eb7a4452-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.58']} DrugCentral uuid:eb7a6e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:eb7a96a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:eb7abfb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:eb7ae84e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:eb7b113e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:eb7b39ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.97']} DrugCentral uuid:eb7b62f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:eb7b9726-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:eb7b9726-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:eb7b9726-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:eb7b9726-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:eb7be5a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:eb7be5a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naltrexone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:eb7c1af2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:eb7c4392-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:eb7c6c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:eb7c952c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:eb7cbe30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:eb7ce6da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1766 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:eb7d0f70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylphenidate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.252']} DrugCentral uuid:eb7d38a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylphenidate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:eb7d615a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylphenidate is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:eb7d8ad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylphenidate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.615']} DrugCentral uuid:eb7db36c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylphenidate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:eb7dde64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylphenidate is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:eb7e08e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylphenidate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:eb7e317a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1768 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylprednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:eb7e59d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1768 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylprednisolone targets Cytosolic other (Annexin A1) DrugCentral uuid:eb7e7ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1768 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylprednisolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:eb7ea75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:1768 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylprednisolone is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eb7ecff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylprednisolone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:eb7ef45c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1771 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylprednisolone succinate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:eb7f2120-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb7f2120-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb7f2120-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:eb7f5938-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.326']} DrugCentral uuid:eb7f81ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:eb7facb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.214']} DrugCentral uuid:eb7fd55c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:eb7ffde8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:eb802692-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:eb804f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:eb807804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.663']} DrugCentral uuid:eb80a0a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:eb80c944-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:eb80f298-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:eb811b2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.213']} DrugCentral uuid:eb8143b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.334']} DrugCentral uuid:eb816d18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eb8196da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:eb81bf70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.054']} DrugCentral uuid:eb81e810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:eb82111e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:eb8239be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:eb82627c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07820 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets Cytosolic other (Induced myeloid leukemia cell differentiation protein Mcl-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:eb828bbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:eb82b4f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:eb82dd92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:eb830614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:eb832e96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:eb835808-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:eb8380a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:eb83a93e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:eb83d990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:eb83d990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:eb83d990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:eb841914-ac81-11ec-8b6b-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:eb84418c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35364 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eb846a40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:eb84936c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:eb84bbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.45']} DrugCentral uuid:eb84e484-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:eb850d56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:eb853786-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metiazinic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:eb856152-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metipranolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:eb8585ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1779 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metipranolol is antagonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:eb85aa54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1780 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metixene is antagonist of GPCR (5-hydroxytryptamine receptor 2C) DrugCentral uuid:eb85cf2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1780 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metixene is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:eb85f3ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1780 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metixene targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:eb861c50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metochalcone targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:eb8644d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:eb866e30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:eb8696e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:eb86bfa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:eb86e856-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.397']} DrugCentral uuid:eb871452-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:eb873fea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:eb8768a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:eb878d60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.509']} DrugCentral uuid:eb87b5ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:eb87de8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:eb880736-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eb883094-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:eb885998-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:eb888224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:eb88aab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:eb88d422-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:eb88fcb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:eb892562-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:eb8952bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:eb8952bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:eb899678-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eb899678-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eb899678-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eb899678-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eb899678-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eb89f726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eb89f726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eb89f726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eb89f726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eb8a49f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eb8a49f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eb8a49f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eb8a9208-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:eb8a9208-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:eb8a9208-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:eb8adf38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:eb8adf38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:eb8adf38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:eb8b2290-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eb8b2290-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eb8b56fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:1782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoclopramide is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:eb8b7f7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1783 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metolazone targets Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.45']} DrugCentral uuid:eb8ba828-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1783 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metolazone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:eb8bcd76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1783 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metolazone targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:eb8bf6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metopimazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:eb8c1fe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metopimazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:eb8c4896-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metopimazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:eb8c7258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eb8c9ce2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eb8cc564-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoprolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:eb8cedfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.79']} DrugCentral uuid:eb8d16d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.83']} DrugCentral uuid:eb8d4746-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eb8d4746-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eb8d4746-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eb8d8670-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:eb8daf9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:eb8dd832-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4LW95 biolink:molecularly_interacts_with DrugCentral:1790 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metronidazole targets Enzyme (Thioredoxin reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:eb8e015e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1791 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metyrapone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:eb8e29c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1791 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:eb8e5424-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15150 biolink:molecularly_interacts_with DrugCentral:1791 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:eb8e7cc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15393 biolink:molecularly_interacts_with DrugCentral:1791 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:eb8ea56e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1791 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metyrapone is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.84']} DrugCentral uuid:eb8ece0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07101 biolink:molecularly_interacts_with DrugCentral:1792 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metirosine is inhibitor of Enzyme (Tyrosine 3-monooxygenase) DrugCentral uuid:eb8ef2da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:eb8f1b2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:eb8f3f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:eb8f64ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:eb8f89de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:eb8fae3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:eb8fd7b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:eb900030-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eb902a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:eb90531e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:eb907bc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:eb90a47c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:eb90cd62-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:eb90f5e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.51']} DrugCentral uuid:eb911e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:eb9146ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:eb917050-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62205 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eb9198be-ac81-11ec-8b6b-0242ac110002 UniProtKB:A2APX8 biolink:molecularly_interacts_with DrugCentral:1794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:eb91c122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:eb91e99a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:eb9215dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:eb923f44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:eb9267bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:eb928c74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:eb92b500-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:eb92dd8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:eb930622-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eb932f3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:eb9357bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:eb938048-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:eb93a8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:eb93d34a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:eb93fbc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:eb942430-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:eb944ca8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eb947606-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:eb949e6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:eb94c6ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:eb94ef64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eb95187c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:eb95423e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:eb956aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02768 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:eb959324-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eb95bd40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14778 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Membrane receptor (Interleukin-1 receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:eb95e5b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41222 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eb96253c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eb96253c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eb96253c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eb96253c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eb96253c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eb96253c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eb96253c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eb9685e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:eb96aeee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:eb96d810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.319']} DrugCentral uuid:eb97009c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:eb972932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.149']} DrugCentral uuid:eb9751b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:eb977d4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:eb97a7fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:eb97d0a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:eb97fac4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.175']} DrugCentral uuid:eb9823c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:eb984c68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:eb9874ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:eb989d8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:eb98c6ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.245']} DrugCentral uuid:eb98ef42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.003']} DrugCentral uuid:eb9917ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.125']} DrugCentral uuid:eb9940c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.465']} DrugCentral uuid:eb996c42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:eb999708-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.526']} DrugCentral uuid:eb99bf8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.541']} DrugCentral uuid:eb99e870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:eb9a10f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:eb9a3992-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:eb9a6214-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:eb9a8b5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:eb9ab52a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:eb9addac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:eb9b064c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:eb9b3068-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:eb9b58f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:eb9b828e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:eb9bab10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:eb9bd414-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:eb9bfc8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:eb9c2590-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:eb9c4eee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:eb9c7766-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:eb9c9ff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:eb9cc87e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:eb9cf272-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:eb9d1b4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:eb9d43e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:eb9d6c8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:eb9d9588-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:eb9dbe28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:eb9de6c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:eb9e0f40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:eb9e3c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:eb9e3c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:eb9e7bc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:eb9e7bc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:eb9e7bc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:eb9e7bc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:eb9ecff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:eb9ecff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:eb9ecff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:eb9f19a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:eb9f19a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:eb9f19a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:eb9f5d1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:eb9f5d1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:eb9f989c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:eb9f989c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:eb9f989c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:eb9fdd0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:eb9fdd0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:eba011be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NG02 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin targets GPCR (G-protein coupled receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:eba03a4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:1796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eba062ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eba08b80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:eba0b682-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:eba0df0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:eba10790-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eba1306c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:eba158f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eba18184-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:eba1aa1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:eba1d346-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:eba1fbd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eba22468-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eba24e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eba277ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eba2a03c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eba2c8c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07652 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil is gating inhibitor of Ion channel (Voltage-dependent R-type calcium channel subunit alpha-1E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:eba2f14a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54282 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil is gating inhibitor of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:eba31a58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:eba342d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15390 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eba36b52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:eba393e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mibefradil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.602']} DrugCentral uuid:eba3bd28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AIC4 biolink:molecularly_interacts_with DrugCentral:1798 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 micafungin targets Unclassified (Beta-1,3-glucan synthase) DrugCentral uuid:eba3e190-ac81-11ec-8b6b-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:1798 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 micafungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) DrugCentral uuid:eba4060c-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.715']} DrugCentral uuid:eba42e8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.137']} DrugCentral uuid:eba45a30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.588']} DrugCentral uuid:eba4837a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:eba4ac06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:eba4d49c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.505']} DrugCentral uuid:eba4fd8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:eba5262c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:eba54ecc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:eba57924-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:eba59dbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:eba5c640-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:eba5eee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.535']} DrugCentral uuid:eba618c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.183']} DrugCentral uuid:eba64250-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.952']} DrugCentral uuid:eba66b5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.452']} DrugCentral uuid:eba6941c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.555']} DrugCentral uuid:eba6bd20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:eba6e5b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.785']} DrugCentral uuid:eba70e4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.964']} DrugCentral uuid:eba736e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.178']} DrugCentral uuid:eba76022-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:eba788ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:eba7b158-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.175']} DrugCentral uuid:eba7da7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.351']} DrugCentral uuid:eba80658-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.386']} DrugCentral uuid:eba82f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.869']} DrugCentral uuid:eba857ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eba88038-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.136']} DrugCentral uuid:eba8a90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.799']} DrugCentral uuid:eba8d1b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.271']} DrugCentral uuid:eba8fa54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.825']} DrugCentral uuid:eba923a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:eba94c5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:eba970c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.923']} DrugCentral uuid:eba9995a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:eba9c2a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.729']} DrugCentral uuid:eba9eb26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:ebaa13a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ebaa3c20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.534']} DrugCentral uuid:ebaa6614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:ebaa8eaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:ebaab754-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:ebaadff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:ebab0920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.381']} DrugCentral uuid:ebab31a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.562']} DrugCentral uuid:ebab5b32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:ebab83d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ebabae5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ebabd6e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.109']} DrugCentral uuid:ebabff88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.792']} DrugCentral uuid:ebac2828-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.326']} DrugCentral uuid:ebac514a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.029']} DrugCentral uuid:ebac79fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.922']} DrugCentral uuid:ebaca2a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.674']} DrugCentral uuid:ebaccbfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.792']} DrugCentral uuid:ebacf4a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.692']} DrugCentral uuid:ebad1d46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.711']} DrugCentral uuid:ebad45f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:ebad6f94-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:ebad98a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22443 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ebadc11a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ebade992-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ebae128c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ebae3b18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:ebae6494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ebae8d2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:ebaeb674-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:ebaedf0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:K4CF70 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (Fatty acid hydroperoxide lyase, chloroplastic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:ebaf0796-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:1800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ebaf2ffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['6']} DrugCentral uuid:ebaf5aca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.353']} DrugCentral uuid:ebaf8360-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebafabf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ebafdcde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:ebafdcde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:ebafdcde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:ebb023c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:ebb023c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:ebb023c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:ebb06aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:ebb06aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:ebb06aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb0e3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebb1c314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:ebb1c314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:ebb1c314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:ebb20a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:ebb20a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:ebb20a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:ebb251b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ebb251b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ebb251b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ebb298de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:ebb298de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:ebb298de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:ebb2dfec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ebb2dfec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ebb2dfec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ebb320d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midodrine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:ebb34554-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midodrine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:ebb36dd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.001']} DrugCentral uuid:ebb396e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.957']} DrugCentral uuid:ebb3bf7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:ebb3e838-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.918']} DrugCentral uuid:ebb41178-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone is antagonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ebb43bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ebb46452-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:ebb48cf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ebb4b59c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ebb4e10c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:ebb509ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone is antagonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:ebb5326a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ebb55b5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:ebb583fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.081']} DrugCentral uuid:ebb5ac72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.255']} DrugCentral uuid:ebb5d51c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.256']} DrugCentral uuid:ebb601f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.374']} DrugCentral uuid:ebb62a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:ebb652f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63449 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.46']} DrugCentral uuid:ebb67b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21447 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Transporter (P-glycoprotein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ebb6a604-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1Q298 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ebb6cea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N1U3 biolink:molecularly_interacts_with DrugCentral:1805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifepristone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ebb6f852-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol is inhibitor of Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ebb720f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04746 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol targets Enzyme (Pancreatic alpha-amylase) DrugCentral uuid:ebb745f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:ebb76e9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol is inhibitor of Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:ebb7973a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ebb7bfc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:ebb7e938-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35574 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ebb811e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ebb83ac8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09848 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ebb86476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q58D55 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:ebb88d3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0HJB3 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol targets Enzyme (Alpha-mannosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:ebb8b5e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56526 biolink:molecularly_interacts_with DrugCentral:1806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglitol targets Enzyme (Alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ebb8de60-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ebb9075a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat is inhibitor of Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ebb93004-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ebb95886-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:ebb9811c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q69ZF3 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ebb9aa66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ebb9d2fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCG7 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:ebb9fc14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ebba2496-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35573 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ebba4ffc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70699 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ebba787e-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5THE3 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ebbaa10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9LGC6 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Putative alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:ebbac996-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70282 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Trehalase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ebbaf768-ac81-11ec-8b6b-0242ac110002 UniProtKB:I3LIR5 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:ebbb20d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O88693 biolink:molecularly_interacts_with DrugCentral:1807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miglustat targets Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:ebbb495c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milnacipran targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ebbb724c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milnacipran is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:ebbb9b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milnacipran is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ebbbc382-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ebbbec2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milnacipran targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:ebbc163e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:ebbc3f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milnacipran targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ebbc6800-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:ebbc908c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:ebbcb9a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:ebbce244-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:ebbd0ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ebbd3366-ac81-11ec-8b6b-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ebbd5c4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ebbd84d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O89085 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ebbdb156-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ebbdb156-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ebbdf238-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ebbdf238-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ebbdf238-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ebbdf238-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ebbe3cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:1810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miltefosine targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:ebbe652e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 miltefosine targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ebbe8e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:1811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mimosine targets Enzyme (Serine hydroxymethyltransferase, cytosolic) DrugCentral uuid:ebbeb416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mimosine targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:ebbedc8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08543 biolink:molecularly_interacts_with DrugCentral:1811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mimosine targets Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:ebbf051a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mimosine targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:ebbf2df6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:1811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mimosine targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ebbf5682-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ebbf7f18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minaprine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ebbfa7ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ebbfd436-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minaprine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ebbffcb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02980 biolink:molecularly_interacts_with DrugCentral:1813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minocycline targets Transporter (Tetracycline resistance protein, class B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.638']} DrugCentral uuid:ebc02558-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z7H2 biolink:molecularly_interacts_with DrugCentral:1813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minocycline targets Unclassified (30S ribosomal protein S4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ka', 'has_quantitative_value': ['6']} DrugCentral uuid:ebc04e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z8T8 biolink:molecularly_interacts_with DrugCentral:1813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minocycline targets Unclassified (30S ribosomal protein S9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ka', 'has_quantitative_value': ['5.756']} DrugCentral uuid:ebc07792-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48048 biolink:molecularly_interacts_with DrugCentral:1814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minoxidil targets Ion channel (ATP-sensitive inward rectifier potassium channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ebc0a442-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minoxidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) DrugCentral uuid:ebc0a442-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minoxidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) DrugCentral uuid:ebc0d28c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:ebc0fb86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:ebc12430-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ebc14cbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:ebc17548-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ebc19fe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:ebc1c8a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:ebc1f14e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:ebc219e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:ebc24342-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:ebc26bd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ebc2946e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:ebc2bdea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:ebc2e2ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:ebc3073c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:ebc32fdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ebc35872-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:ebc384b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebc3af98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:ebc3d824-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:ebc40182-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ebc431de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ebc431de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ebc431de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ebc47144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ebc49a48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ebc4c2e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ebc4eb60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 misoprostol targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.028']} DrugCentral uuid:ebc517fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitiglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ebc517fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitiglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ebc54e34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1819 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitomycin targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ebc577ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitotane targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:ebc5a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitotane targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:ebc5c954-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitotane targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:ebc5f2d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitotane targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.512']} DrugCentral uuid:ebc61b84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitotane targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.186']} DrugCentral uuid:ebc6441a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitotane targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ebc66d1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitotane targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:ebc69776-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitotane is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) DrugCentral uuid:ebc6bbd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10109 biolink:molecularly_interacts_with DrugCentral:1820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitotane targets Unclassified (Adrenodoxin, mitochondrial) DrugCentral uuid:ebc6e064-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05108 biolink:molecularly_interacts_with DrugCentral:1820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitotane is inhibitor of Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) DrugCentral uuid:ebc704d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.532']} DrugCentral uuid:ebc72fce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.841']} DrugCentral uuid:ebc75850-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.306']} DrugCentral uuid:ebc780dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.729']} DrugCentral uuid:ebc7aa26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.744']} DrugCentral uuid:ebc7d2b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:ebc7fb66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.047']} DrugCentral uuid:ebc823e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:ebc848aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC90', 'has_quantitative_value': ['5.959']} DrugCentral uuid:ebc87136-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.287']} DrugCentral uuid:ebc899ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kact', 'has_quantitative_value': ['5.155']} DrugCentral uuid:ebc8c24e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.269']} DrugCentral uuid:ebc8eca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ebc91744-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.691']} DrugCentral uuid:ebc93fb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:ebc9683e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:ebc9917e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ebc9ba14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.748']} DrugCentral uuid:ebc9e282-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ebca0b04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ebca33cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ebca5c58-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:ebca85d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ebcaae56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ebcad7e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:ebcb004a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29372 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Enzyme (DNA-3-methyladenine glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ebcb28ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:1821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoxantrone targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:ebcb5310-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1822 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mivacurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:ebcb7f34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:ebcb7f34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:ebcb7f34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:ebcbb760-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mizolastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.456']} DrugCentral uuid:ebcbdfd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mizolastine targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:ebcc04d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mizolastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:ebcc2d94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moclobemide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ebcc5616-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moclobemide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ebcc7f38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:ebccaa12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moclobemide is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ebccd28a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:ebccfb2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:1825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ebcd2460-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:1825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:ebcd4cec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1826 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 modafinil targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ebcd7564-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1826 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 modafinil is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:ebcd9e0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1826 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 modafinil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:ebcdc2da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1826 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 modafinil targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.396']} DrugCentral uuid:ebcdeb70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1826 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 modafinil targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:ebce0fce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1826 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 modafinil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ebce3846-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1826 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 modafinil targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:ebce62a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moexipril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:ebce8b3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:ebceb3c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:ebcedc56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:ebcf0578-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:ebcf2e18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.157']} DrugCentral uuid:ebcf5690-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ebcf7f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:ebcfa82a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.421']} DrugCentral uuid:ebcfd0ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ebcff94c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ebd021d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:ebd04c08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:ebd07494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:ebd09d20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.254']} DrugCentral uuid:ebd0c5b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ebd0eef6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ebd118b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ebd1414e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.763']} DrugCentral uuid:ebd16a48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ebd192c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:ebd1bb24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ebd1e3b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molindone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ebd20dae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 molsidomine targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:ebd2384c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mometasone furoate targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:ebd261d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mometasone furoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:ebd28a5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mometasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:ebd2b362-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1834 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 monobenzone targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.429']} DrugCentral uuid:ebd2dbda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1834 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 monobenzone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.992']} DrugCentral uuid:ebd3047a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1834 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 monobenzone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.414']} DrugCentral uuid:ebd32d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1834 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 monobenzone is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:ebd3525e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1834 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 monobenzone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.311']} DrugCentral uuid:ebd37ae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ebd3a39e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.833']} DrugCentral uuid:ebd3cc34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.574']} DrugCentral uuid:ebd3f812-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ebd420ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:ebd449a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.713']} DrugCentral uuid:ebd47224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.853']} DrugCentral uuid:ebd49b6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.495']} DrugCentral uuid:ebd4c418-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.115']} DrugCentral uuid:ebd4ecc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:ebd515bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:ebd53e5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.958']} DrugCentral uuid:ebd566fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.772']} DrugCentral uuid:ebd58fc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ebd5b9d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.328']} DrugCentral uuid:ebd5e46a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.495']} DrugCentral uuid:ebd60cf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:ebd63582-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.817']} DrugCentral uuid:ebd65f94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ebd68848-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.068']} DrugCentral uuid:ebd6b0d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.895']} DrugCentral uuid:ebd6d974-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ebd703cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast targets GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:ebd72c6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6NS65 biolink:molecularly_interacts_with DrugCentral:1836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 montelukast is antagonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:ebd754ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ebd77d84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:ebd7a8ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1837 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.134']} DrugCentral uuid:ebd7d158-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1842 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moracizine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:ebd7f5d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.86']} DrugCentral uuid:ebd81f14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ebd847be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ebd87072-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ebd898fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:ebd8c20c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:ebd8eaac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:ebd9134c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ebd93bc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:ebd96694-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:ebd9911e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:ebd9b9be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ebd9e240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79350 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ebda0b94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47748 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:ebda3fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ebda3fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ebda3fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ebda3fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ebda9b54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:ebda9b54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:ebda9b54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:ebda9b54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:ebda9b54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:ebdafc34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:ebdafc34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:ebdafc34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:ebdafc34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:ebdb48a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q98UH1 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Mu opioid receptor-like OR2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:ebdb713c-ac81-11ec-8b6b-0242ac110002 UniProtKB:B3DH72 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Opioid receptor, delta 1b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ebdb99e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O57585 biolink:molecularly_interacts_with DrugCentral:1845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 morphine targets GPCR (Opioid receptor homologue) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:ebdbc27c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1847 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapramine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:ebdbebbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1847 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapramine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:ebdc1592-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:ebdc3e3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:ebdc6740-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.891']} DrugCentral uuid:ebdc8fe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:ebdcb862-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:ebdce0ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.694']} DrugCentral uuid:ebdd0af6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.725']} DrugCentral uuid:ebdd362a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.683']} DrugCentral uuid:ebdd5eca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ebdd876a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ebddb1a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ebddda26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:ebde02b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ebde2f1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ebde2f1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ebde6360-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:1848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mosapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ebde8c0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:1851 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 latamoxef is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.938']} DrugCentral uuid:ebdeb4a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:1851 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 latamoxef is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.716']} DrugCentral uuid:ebdede80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:1851 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 latamoxef is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.637']} DrugCentral uuid:ebdf08d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:ebdf2d40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1854 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ebdf55d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1854 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxifloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ebdf82f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:1854 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:ebdf82f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:1854 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:ebdfb5ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1854 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxifloxacin is inhibitor of Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ebdfb5ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1854 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxifloxacin is inhibitor of Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ebdfea00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1856 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ebe01304-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1856 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.397']} DrugCentral uuid:ebe03bae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1856 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxonidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ebe06444-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:1856 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ebe08cd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1856 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:ebe0b6d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:1856 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxonidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:ebe0e2b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:1856 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxonidine is agonist of Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:ebe10bce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00956 biolink:molecularly_interacts_with DrugCentral:1857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:ebe13478-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41252 biolink:molecularly_interacts_with DrugCentral:1857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ebe15d86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41972 biolink:molecularly_interacts_with DrugCentral:1857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mupirocin is inhibitor of Enzyme (Isoleucine--tRNA ligase) DrugCentral uuid:ebe181f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99YW3 biolink:molecularly_interacts_with DrugCentral:1857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mupirocin is inhibitor of Enzyme (Isoleucine--tRNA ligase) DrugCentral uuid:ebe1a73c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56690 biolink:molecularly_interacts_with DrugCentral:1857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ebe1d112-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mycophenolate mofetil is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:ebe1fa34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:1859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mycophenolate mofetil is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:ebe222d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mycophenolic acid targets Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:ebe24b60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:1860 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mycophenolic acid targets Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ebe277fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mycophenolic acid is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase (IMPDH)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ebe277fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mycophenolic acid is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase (IMPDH)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ebe2af56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5KP44 biolink:molecularly_interacts_with DrugCentral:1860 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mycophenolic acid targets Unclassified (Inosine-5'-monophosphate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ebe2d80a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nabilone is agonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ebe300aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:1862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nabilone targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:ebe329d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:1862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nabilone targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:ebe35280-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:1862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nabilone targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:ebe37b34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nabumetone is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:ebe39f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nabumetone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.34']} DrugCentral uuid:ebe3c878-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nabumetone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.732']} DrugCentral uuid:ebe3f10e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nabumetone targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ebe41990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nabumetone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.001']} DrugCentral uuid:ebe4421c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nadolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ebe46c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nadolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:ebe494ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nadolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ebe4bd8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ebe4e604-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:ebe50f4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat is inhibitor of Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ebe537d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06870 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat targets Enzyme (Kallikrein-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ebe56066-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:ebe589d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:ebe5b372-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00736 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat is inhibitor of Enzyme (Complement C1r subcomponent) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ebe5dbfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09871 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat targets Enzyme (Complement C1s subcomponent) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ebe604a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16515 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:ebe62e88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ebe658e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ebe6816c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ebe6aa0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15661 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat is inhibitor of Enzyme (Tryptase alpha/beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:ebe6d342-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:ebe6fbec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04756 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat targets Enzyme (Hepatocyte growth factor activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ebe72496-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15393 biolink:molecularly_interacts_with DrugCentral:1867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafamostat is inhibitor of Enzyme (Transmembrane protease serine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ebe74d40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafarelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.699']} DrugCentral uuid:ebe77644-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafcillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:ebe7ab3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ebe7ab3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ebe7ab3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ebe7ab3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ebe7ab3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ebe7f718-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftidrofuryl targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ebe82328-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftifine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ebe84c4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftifine targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ebe874cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:1872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftifine targets Enzyme (Squalene monooxygenase) DrugCentral uuid:ebe899e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:1872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftifine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:ebe8be64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftifine targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:ebe8e6e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O07855 biolink:molecularly_interacts_with DrugCentral:1872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftifine targets Enzyme (Dehydrosqualene desaturase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:ebe90f5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftopidil targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ebe94032-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ebe94032-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ebe94032-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ebe9883a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:ebe9883a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:ebe9883a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:ebe9c796-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftopidil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:ebe9f0ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftopidil is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:ebea19a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naftopidil is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:ebea425c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1874 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalbuphine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ebea6b10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1874 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalbuphine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ebea945a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1874 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalbuphine is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ebeabcfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1874 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalbuphine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ebeae57c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalidixic acid targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ebeb1286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalidixic acid is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ebeb1286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalidixic acid is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ebeb410c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalmefene is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.53']} DrugCentral uuid:ebeb69ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalmefene is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:ebeb931e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalmefene is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:ebebbd44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalmefene targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:ebebe5e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalmefene targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:ebec0e84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalmefene targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebec372e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:ebec6082-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:ebec8904-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:ebecb2bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ebecdb70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ebed056e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ebed39b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ebed39b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ebed39b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ebed39b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ebed90ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:ebed90ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:ebed90ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:ebed90ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:ebeddb24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:ebee03b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:ebee2ce6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ebee5568-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:ebee7e12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:ebeea6b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ebeecfa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ebeef856-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:ebef20e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ebef495a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:ebef72cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:ebef9b62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ebefc3f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ebefed24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79350 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ebf015a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51682 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.98']} DrugCentral uuid:ebf049c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ebf049c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ebf049c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ebf049c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ebf095f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1879 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:ebf0ba60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1879 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:ebf0e30a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1879 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ebf10baa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1879 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:ebf1356c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1879 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.678']} DrugCentral uuid:ebf15df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1879 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:ebf186a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone decanoate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:ebf1ac4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone decanoate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:ebf1d580-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone decanoate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ebf1fede-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone decanoate targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:ebf2274c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone decanoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:ebf24ff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone decanoate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:ebf27940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone phenpropionate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ebf2a1d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nandrolone phenpropionate is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.5']} DrugCentral uuid:ebf2cae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ebf2f370-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ebf31ed6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ebf3474e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:ebf36fc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ebf398a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ebf3c124-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ebf3e9a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ebf4123c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ebf44036-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ebf44036-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naproxen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ebf4740c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1884 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naratriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:ebf49cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1884 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:ebf4c560-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1884 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.796']} DrugCentral uuid:ebf4ef04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1884 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:ebf517a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1884 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ebf54044-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:1886 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nateglinide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ebf56d1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:ebf56d1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:ebf5a50c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:ebf5a50c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:ebf5d914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nebivolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:ebf601be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nebivolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ebf62b12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nebivolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ebf653a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nebivolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:ebf67c48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1887 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nebivolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:ebf6a5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:1889 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nedocromil targets GPCR (Cysteinyl leukotriene receptor 1) DrugCentral uuid:ebf6ccde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1889 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nedocromil is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.013']} DrugCentral uuid:ebf6f588-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:ebf71e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ebf7486c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.699']} DrugCentral uuid:ebf77120-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.444']} DrugCentral uuid:ebf799ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:ebf7c24c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ebf7ecb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.143']} DrugCentral uuid:ebf81544-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.789']} DrugCentral uuid:ebf83df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.635']} DrugCentral uuid:ebf866fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:ebf8923a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.444']} DrugCentral uuid:ebf8be0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:ebf8e776-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:ebf91002-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:ebf938de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:ebf9616a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ebf989e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ebf9b32c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:ebf9dbb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:ebfa0426-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ebfa2ca8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:ebfa5692-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1891 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefopam targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:ebfa7d70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1891 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefopam targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:ebfaa624-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1891 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefopam targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:ebfaceba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1891 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:ebfaf7b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1891 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.481']} DrugCentral uuid:ebfb204a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1891 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.252']} DrugCentral uuid:ebfb48e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1891 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nefopam targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:ebfb716c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.232']} DrugCentral uuid:ebfb9aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.189']} DrugCentral uuid:ebfbc356-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:ebfbece6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ebfc1568-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.057']} DrugCentral uuid:ebfc413c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.209']} DrugCentral uuid:ebfc6a40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.592']} DrugCentral uuid:ebfc92ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.909']} DrugCentral uuid:ebfcbb8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.078']} DrugCentral uuid:ebfce470-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.842']} DrugCentral uuid:ebfd0d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.632']} DrugCentral uuid:ebfd35ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.255']} DrugCentral uuid:ebfd5ff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:ebfd8484-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.101']} DrugCentral uuid:ebfdad10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.098']} DrugCentral uuid:ebfdd5b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.676']} DrugCentral uuid:ebfdff90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.648']} DrugCentral uuid:ebfe286c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.739']} DrugCentral uuid:ebfe50f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:ebfe798e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.615']} DrugCentral uuid:ebfea288-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:ebfecb14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.236']} DrugCentral uuid:ebfef440-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:ebff1cfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:ebff462a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:ebff6eca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nelfinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:ebff9756-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1895 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nemonapride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ebffbff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1895 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nemonapride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:ebffec06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1895 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nemonapride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:ec0018ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1895 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nemonapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:ec004174-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1895 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nemonapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.31']} DrugCentral uuid:ec006a5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1895 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nemonapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:ec0092fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:1896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 framycetin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ec00bb90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:1896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 framycetin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:ec00dfda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08312 biolink:molecularly_interacts_with DrugCentral:1896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 framycetin targets Enzyme (Phenylalanine--tRNA ligase alpha subunit) DrugCentral uuid:ec0104e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07395 biolink:molecularly_interacts_with DrugCentral:1896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 framycetin targets Enzyme (Phenylalanine--tRNA ligase beta subunit) DrugCentral uuid:ec01294a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:1896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 framycetin targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ec0151ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95237 biolink:molecularly_interacts_with DrugCentral:1896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 framycetin targets Enzyme (Lecithin retinol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:ec017a62-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:1896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 framycetin targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.81']} DrugCentral uuid:ec01a424-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48442 biolink:molecularly_interacts_with DrugCentral:1896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 framycetin is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:ec01cfee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:ec01fb90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ec022412-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:ec024d20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:ec027598-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ec029e2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ec02c6ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1899 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nepafenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ec02eff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1899 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nepafenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ec031cdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1899 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ec031cdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1899 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ec0355bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1899 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ec0355bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1899 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ec038b04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1900 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nepinalone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:ec03b3b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nesiritide is agonist of Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:ec03d816-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:1904 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nevirapine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:ec04019c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1904 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nevirapine targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ec042b0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1904 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nevirapine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ec0453ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1904 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nevirapine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ec047c1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:1904 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nevirapine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ec04a4c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets GPCR (Hydroxycarboxylic acid receptor 2) DrugCentral uuid:ec04ca0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets GPCR (Hydroxycarboxylic acid receptor 3) DrugCentral uuid:ec04ee5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40261 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets Enzyme (Nicotinamide N-methyltransferase) DrugCentral uuid:ec05129e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15274 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets Enzyme (Nicotinate-nucleotide pyrophosphorylase [carboxylating]) DrugCentral uuid:ec05371a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96EB6 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacetylase sirtuin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ec0561ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IXJ6 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacetylase sirtuin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ec058abc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ec05b320-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53686 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets Enzyme (NAD-dependent deacetylase HST2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:ec05db98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NTG7 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets Enzyme (NAD-dependent deacetylase sirtuin 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ec0604a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:ec062d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8I6E4 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets Unclassified (Putative silent information regulator 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ec0655c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:1906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinamide targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:ec067e4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.377']} DrugCentral uuid:ec06a730-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:ec06cfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ec06f834-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:ec071d50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:ec0748c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ec07716a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.553']} DrugCentral uuid:ec0799e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.553']} DrugCentral uuid:ec07c336-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:ec07ebd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:ec081570-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec083dfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O54698 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ec086700-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:ec089748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ec089748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ec089748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ec08dffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ec08dffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ec08dffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ec0927da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:ec0927da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:ec0927da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:ec096b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:ec096b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:ec0999f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ec09c280-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15385 biolink:molecularly_interacts_with DrugCentral:1909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicardipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ec09eb20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.046']} DrugCentral uuid:ec0a13ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:ec0a3c9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:ec0a6528-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ec0a8d96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:ec0ab618-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ec0ae002-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:ec0b088e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:ec0b3192-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:ec0b5b0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:ec0b843a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:ec0bacda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:ec0bd566-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:ec0bfdfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5JUK3 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ec0c26e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ec0c4f64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:1912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niclosamide targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ec0c77e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1919 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicorandil targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:ec0ca130-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48048 biolink:molecularly_interacts_with DrugCentral:1919 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicorandil targets Ion channel (ATP-sensitive inward rectifier potassium channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:ec0cc99e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1919 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicorandil targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ec0cf20c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:ec0d1aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ec0d43ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.356']} DrugCentral uuid:ec0d6c50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ec0d94f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ec0dbd68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ec0de676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.03']} DrugCentral uuid:ec0e0f2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ec0e390a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49582 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:ec0e61b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43144 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ec0e8bee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit beta-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:ec0eb4ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04757 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:ec0edd56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12389 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ec0f060a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WSF8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Unclassified (Soluble acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ec0f304e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:ec0f58bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21687 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Enzyme (Lycopene cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:ec0f8148-ac81-11ec-8b6b-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:ec0faa60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25162 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit beta-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ec0fd2f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09482 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:ec0ffb96-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70174 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ec102800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ec102800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ec10611c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ec10611c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ec1098f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ec1098f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ec10d142-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ec10d142-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ec1109be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ec1109be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ec11419a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ec11419a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec11a446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:ec125bac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ec125bac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ec1294fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:ec1294fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:ec12cd58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:ec12cd58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:ec130534-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:ec130534-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:ec133d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ec133d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ec138112-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:ec138112-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:ec138112-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:ec138112-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:ec138112-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:ec13e274-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:ec13e274-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:ec13e274-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:ec13e274-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:ec143d8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:ec143d8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:ec143d8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:ec143d8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:ec148c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ec148c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ec14cbb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ec14cbb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ec14cbb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ec14cbb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ec152562-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ec152562-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ec152562-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ec152562-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ec152562-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ec157b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:ec15a3fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:ec15cdf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ec15f992-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62897 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ec162282-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotine targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ec164c26-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.089']} DrugCentral uuid:ec167566-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.65']} DrugCentral uuid:ec169eec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ec16c764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ec16efc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:ec1718d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.019']} DrugCentral uuid:ec17416c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.348']} DrugCentral uuid:ec1769f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:ec179324-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:ec17bf66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:ec17e8c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ec18116e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec183a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:ec186326-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.672']} DrugCentral uuid:ec188bbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:ec18b434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:ec18dd24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine is inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ec1905c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ec192e50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.355']} DrugCentral uuid:ec1956d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine is antagonist of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ec198170-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16389 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ec19ad30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:ec19d7f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.731']} DrugCentral uuid:ec1a0078-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:ec1a29c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec1a524e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine is antagonist of Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ec1a7bde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.821']} DrugCentral uuid:ec1aa49c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ec1acd3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ec1af5b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:ec1b1e4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ec1b4820-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:ec1b7124-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:ec1b99ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ec1bc250-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ec1beb72-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35505 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:ec1c1bd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:ec1c1bd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:ec1c1bd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:ec1c641c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:ec1c641c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:ec1c641c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:ec1ca404-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:ec1ccc68-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:ec1cf4f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ec1d1ea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16388 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ec1d472e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63142 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ec1d7046-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ec1d98f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1922 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifedipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ec1dc23a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1923 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifekalant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ec1debb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1923 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifekalant targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:ec1e1438-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1923 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifekalant targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ec1e3cc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1923 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifekalant targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ec1e6582-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niflumic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.037']} DrugCentral uuid:ec1e8e04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niflumic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.973']} DrugCentral uuid:ec1eb690-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:1925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niflumic acid targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ec1edef4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niflumic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ec1f0960-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51800 biolink:molecularly_interacts_with DrugCentral:1925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niflumic acid is activator of Ion channel (Chloride channel protein ClC-Ka) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ec1f31c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6UVM3 biolink:molecularly_interacts_with DrugCentral:1925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niflumic acid is activator of Ion channel (Potassium channel subfamily T member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:ec1f5a3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niflumic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ec1f82dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51801 biolink:molecularly_interacts_with DrugCentral:1925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niflumic acid is activator of Ion channel (Chloride channel protein ClC-Kb) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ec1fac1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niflumic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ec1fd49e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:1928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifuroxazide targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ec1ffd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:ec20261a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:ec204eb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:ec207728-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ec209fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:ec20c994-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ec20f28e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ec211b24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:ec2143c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ec216cf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ec219568-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.83']} DrugCentral uuid:ec21bdf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ec21e874-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ec221182-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.33']} DrugCentral uuid:ec223a04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ec226286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ec228b08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:ec22b4ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:ec22dd4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:ec2305e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ec232e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ec235808-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:ec2380a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.13']} DrugCentral uuid:ec23a934-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.387']} DrugCentral uuid:ec23d238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:ec23fa9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ec242332-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:ec244bc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:ec2475ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ec24a19a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.069']} DrugCentral uuid:ec24cd64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ec24f64a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:ec251f9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:ec2547f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:ec257084-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.318']} DrugCentral uuid:ec2598fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:ec25c1f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.096']} DrugCentral uuid:ec25eb7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ec261412-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:ec263c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:ec266908-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ec2693ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ec26bc3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.141']} DrugCentral uuid:ec26e55e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ec270de0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:ec27364e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ec275eda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:ec2787d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:ec27b056-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ec27d8c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ec28027c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ec282cf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ec285592-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:ec287e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:ec28a6a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ec28cfe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ec28f86c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:ec292102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ec29497a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ec297274-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:ec299b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ec29c36e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ec29ee2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ec2a19ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ec2a426c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ec2a6aee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:ec2a94b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:ec2abd32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:ec2ae5c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ec2b0e54-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ec2b376c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ec2b5fe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:ec2b885c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ec2bb0de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ec2bdf64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:ec2bdf64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1932 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilotinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:ec2c1376-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1933 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec2c3bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilvadipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:ec2c610a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilvadipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:ec2c8572-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilvadipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:ec2cadb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilvadipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:ec2cadb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nilvadipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:ec2cdc0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:ec2d04fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ec2d2d9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.927']} DrugCentral uuid:ec2d561e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:ec2d7e8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ec2da984-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ec2dd54e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.632']} DrugCentral uuid:ec2dfdda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ec2e2666-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ec2e4f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2A865 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:ec2e7832-ac81-11ec-8b6b-0242ac110002 UniProtKB:L8I2E6 biolink:molecularly_interacts_with DrugCentral:1935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimesulide targets Enzyme (Dipeptidyl peptidase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.16']} DrugCentral uuid:ec2ea0b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.364']} DrugCentral uuid:ec2ec9a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:ec2ef226-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:ec2f1aa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.072']} DrugCentral uuid:ec2f435c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ec2f6d0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:ec2f9190-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ec2fba26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:ec2fde8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:ec3003aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec302c2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.252']} DrugCentral uuid:ec3054b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec307d44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:ec30a634-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ec30cf60-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec30f7c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ec312032-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:ec314a76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ec3175e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ec319fee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.642']} DrugCentral uuid:ec31c97e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.638']} DrugCentral uuid:ec31f2b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine targets Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) DrugCentral uuid:ec321712-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.395']} DrugCentral uuid:ec323fb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ec32683e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:ec328d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:ec32b5b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec32e624-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:ec32e624-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:ec32e624-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:ec3327b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01815 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ec3350c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99246 biolink:molecularly_interacts_with DrugCentral:1942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ec337a6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1943 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitazoxanide targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ec33a2f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q968X7 biolink:molecularly_interacts_with DrugCentral:1943 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitazoxanide is inhibitor of Enzyme (Pyruvate dehydrogenase [NADP(+)]) DrugCentral uuid:ec33c828-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q24982 biolink:molecularly_interacts_with DrugCentral:1943 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitazoxanide is inhibitor of Enzyme (Pyruvate:ferredoxin oxidoreductase) DrugCentral uuid:ec33ec90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0P8E1 biolink:molecularly_interacts_with DrugCentral:1943 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitazoxanide targets Enzyme (Pyruvate-flavodoxin oxidoreductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:ec341526-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32754 biolink:molecularly_interacts_with DrugCentral:1944 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitisinone is inhibitor of Enzyme (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:ec343d76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02110 biolink:molecularly_interacts_with DrugCentral:1944 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitisinone targets Enzyme (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ec346652-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32755 biolink:molecularly_interacts_with DrugCentral:1944 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitisinone targets Unclassified (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ec3496a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ec3496a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ec3496a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ec34e988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ec34e988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ec34e988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ec34e988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ec34e988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ec34e988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ec354b80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ec3573f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.081']} DrugCentral uuid:ec359d38-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine is blocker of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ec35c5ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:ec35ea0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.921']} DrugCentral uuid:ec361290-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ec363b8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:ec366402-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.056']} DrugCentral uuid:ec368c8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:ec36b506-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec36e0da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ec3709f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:ec37327e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec375bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec378436-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21556 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:ec37b474-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:ec37b474-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:ec37b474-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:ec37f43e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1947 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrendipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:ec3828aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:ec3828aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:ec3828aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:ec3828aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:ec386cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:1949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrofurantoin targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:ec389236-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrofurantoin targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:ec38bacc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:1950 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrofurazone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:ec38df34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P83512 biolink:molecularly_interacts_with DrugCentral:1950 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitrofurazone targets Enzyme (Snake venom metalloproteinase Bap1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:ec3907ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glyceryl trinitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:ec39388a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:ec39388a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:ec39388a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:ec39388a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:ec397a98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroxoline targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ec39a31a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:1954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroxoline targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ec39cc32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:1954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroxoline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:ec39f4b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroxoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ec3a1d4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:1954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroxoline targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ec3a45d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:1954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroxoline targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ec3a6f3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1955 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nizatidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ec3a97de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1955 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nizatidine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.251']} DrugCentral uuid:ec3ac06a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ec3ae900-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:ec3b122c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:ec3b3a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ec3b6344-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:ec3b8bc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['2.947']} DrugCentral uuid:ec3bb4ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.963']} DrugCentral uuid:ec3bdd4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ec3c05ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:ec3c2f54-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:ec3c5b1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ec3c87d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets Enzyme (Hemoglobin HbA) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.678']} DrugCentral uuid:ec3c87d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nomifensine targets Enzyme (Hemoglobin HbA) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.678']} DrugCentral uuid:ec3cbbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1959 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norelgestromin is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:ec3ce14c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ec3d0a0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ec3d32aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ec3d5b40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ec3d8458-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:ec3dae24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ec3dd6b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ec3dff32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.367']} DrugCentral uuid:ec3e2b06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ec3e5680-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.071']} DrugCentral uuid:ec3e7f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ec3ea860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:ec3ed10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:ec3ef996-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ec3f2286-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ec3f4b94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ec3f7416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ec3f9ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:ec3fc51a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10608 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:ec3fef5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:ec401826-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ec404990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:ec404990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:ec404990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:ec40912a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ec40912a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ec40912a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ec40e3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ec40e3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ec40e3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ec40e3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ec40e3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ec40e3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ec414cd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec414cd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec414cd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec418be8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01337 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ec41b50a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:1960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norepinephrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ec41de04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethisterone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.618']} DrugCentral uuid:ec42069a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethisterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.706']} DrugCentral uuid:ec422f44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethisterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.636']} DrugCentral uuid:ec425988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethisterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:ec428228-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethisterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['11.26']} DrugCentral uuid:ec42aabe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethisterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.97']} DrugCentral uuid:ec42d354-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethisterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ec42fd34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethisterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.914']} DrugCentral uuid:ec432ac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethisterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:ec432ac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1962 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethisterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:ec435e96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1963 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethindrone acetate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ec438722-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1963 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.533']} DrugCentral uuid:ec43b2ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1963 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:ec43db5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1963 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:ec4403f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1963 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethindrone acetate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['11.26']} DrugCentral uuid:ec442cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1963 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethindrone acetate targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:ec445558-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1963 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethindrone acetate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.97']} DrugCentral uuid:ec447e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1963 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethindrone acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.149']} DrugCentral uuid:ec44a68e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1963 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethindrone acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.441']} DrugCentral uuid:ec44cfec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1965 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethynodrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:ec44f44a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1965 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norethynodrel targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:ec451ccc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ec45454e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ec456efc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ec459788-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ec45c00a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AFI2 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ec45e896-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:ec46117c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:ec463a12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ec4662b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ec468b34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ec46b46a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ec46ddfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec4741be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec481512-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37340 biolink:molecularly_interacts_with DrugCentral:1967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norfloxacin targets Unclassified (Multidrug resistance protein mdtK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.01']} DrugCentral uuid:ec483da8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1968 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norgestimate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:ec48622e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13507 biolink:molecularly_interacts_with DrugCentral:1968 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norgestimate is blocker of Ion channel (Short transient receptor potential channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ec488b8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y210 biolink:molecularly_interacts_with DrugCentral:1968 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 norgestimate is blocker of Ion channel (Short transient receptor potential channel 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ec48b418-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:ec48dcb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ec490558-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:ec492ee8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:ec49590e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.36']} DrugCentral uuid:ec4981b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.509']} DrugCentral uuid:ec49aad0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.356']} DrugCentral uuid:ec49d398-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:ec49fc24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ec4a24e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:ec4a4e0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:ec4a769a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ec4a9f4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:ec4ac7ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.033']} DrugCentral uuid:ec4af17e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.639']} DrugCentral uuid:ec4b1a14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:ec4b42a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:ec4b6b36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:ec4b9426-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.076']} DrugCentral uuid:ec4bbcb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:ec4be52a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.071']} DrugCentral uuid:ec4c0db6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:ec4c3700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.921']} DrugCentral uuid:ec4c5f8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['6.225']} DrugCentral uuid:ec4c894e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:ec4cb2b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:ec4cdb4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ec4d03d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.943']} DrugCentral uuid:ec4d2c78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:ec4d5752-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:ec4d8632-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:ec4daeb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:ec4dd74a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78508 biolink:molecularly_interacts_with DrugCentral:1971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nortriptyline is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.796']} DrugCentral uuid:ec4e0026-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 noscapine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.087']} DrugCentral uuid:ec4e289e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 noscapine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:ec4e5116-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 noscapine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ec4e7984-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 noscapine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:ec4ea4b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:ec4ecd1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:ec4ef5b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A4L9 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:ec4f1e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7X1P7 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Enzyme (ParE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:ec4f4760-ac81-11ec-8b6b-0242ac110002 UniProtKB:C3SLN2 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:ec4f73e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ec4f73e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ec4fabba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5HK04 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ec4fabba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5HK04 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ec4fdb08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C559 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ec500380-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A0K8 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ec502c20-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0QNE0 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Enzyme (DNULL gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:ec5054c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:C3SLN3 biolink:molecularly_interacts_with DrugCentral:1974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 novobiocin targets Enzyme (DNULL gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ec5085da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ec5085da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ec5085da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ec50c518-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:ec50edcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.699']} DrugCentral uuid:ec511810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ec5140c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:ec516964-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide targets GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:ec5191f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide targets GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:ec51bb08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ec51e39e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.98']} DrugCentral uuid:ec520c52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:ec52377c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ec526224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30936 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ec528b1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08858 biolink:molecularly_interacts_with DrugCentral:1980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:ec52b3e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:ec52dd1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ec530594-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:ec532e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ec5356ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:ec537b6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ec53a404-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03362 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Polyprotein (Gag-Pro-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec5406d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec54dbbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47154 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Enzyme (CAAX prenyl protease 1) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:ec550416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:1981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofloxacin targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:ec552c70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ec555556-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ec557e00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:ec55a6aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.523']} DrugCentral uuid:ec55cf40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.492']} DrugCentral uuid:ec55fa56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ec5622ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:ec564b5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ec567418-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.319']} DrugCentral uuid:ec569e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:ec56c706-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:ec56efb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:ec5718b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:ec574208-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:ec576aa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:ec57942e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:ec57be72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:ec57e9e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:ec581296-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.356']} DrugCentral uuid:ec583b36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.506']} DrugCentral uuid:ec586462-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.102']} DrugCentral uuid:ec588d02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.136']} DrugCentral uuid:ec58b598-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.682']} DrugCentral uuid:ec58de2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:ec59073c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:ec592fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.233']} DrugCentral uuid:ec595854-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.121']} DrugCentral uuid:ec5980fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:ec59abb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:ec59d45a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:ec59fcfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:ec5a2658-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:ec5a4f02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.916']} DrugCentral uuid:ec5a77a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.509']} DrugCentral uuid:ec5aa04c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ec5ac950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.558']} DrugCentral uuid:ec5af1f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:ec5b1a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.364']} DrugCentral uuid:ec5b4330-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ec5b6dec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:ec5b995c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:ec5bc224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ec5beace-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ec5c1418-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ec5c3ccc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:ec5c6558-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ec5c8e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec5cb828-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:ec5ce0c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:ec5d095e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ec5d32da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:ec5d5b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ec5d8bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ec5d8bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ec5d8bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ec5dd3ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ec5dd3ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ec5dd3ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ec5e1330-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:ec5e3b9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:1982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olanzapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ec5e6538-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1985 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olmesartan medoxomil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ec5e8db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:1985 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olmesartan medoxomil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:ec5eb63c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1986 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olopatadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.284']} DrugCentral uuid:ec5edee6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1986 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olopatadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ec5f0cae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olprinone is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:ec5f0cae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olprinone is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:ec5f3c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1988 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olsalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:ec5f60aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1988 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olsalazine is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:ec5f890e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1988 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olsalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:ec5f890e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1988 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olsalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:ec5fb816-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omapatrilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ec5fe08e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:1989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omapatrilat targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec60092e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omapatrilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ec6031b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07861 biolink:molecularly_interacts_with DrugCentral:1989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omapatrilat targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ec605a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omapatrilat targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ec6082fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omapatrilat targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ec60ab7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.31']} DrugCentral uuid:ec60d41c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.051']} DrugCentral uuid:ec60ff14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.347']} DrugCentral uuid:ec61278c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:ec61500e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ec617958-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ec61a5e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ec61a5e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ec61dec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19156 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ec61dec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19156 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ec62132c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ec623bb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:ec62644e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ec6290d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:ec6290d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:1990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:ec62c6c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:ec62f04e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:ec6318d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.678']} DrugCentral uuid:ec63413e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ec636aa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:ec639314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:ec63bb96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ec63e49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ec640d1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ec6435bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ec645ed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ec6488a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ec64b17c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ec64da12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35563 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:ec6502bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ec652bfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ec655492-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ec657d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ec65a5a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:ec65d296-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:ec65d296-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:ec660a68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:ec660a68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:ec66460e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ec66460e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ec66460e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ec668dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ec668dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ec66c1b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:1992 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ondansetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ec66ea50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1993 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 opipramol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ec6713c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1993 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 opipramol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:ec673d84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1993 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 opipramol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ec67661a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ec678f50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Lipoprotein lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.18']} DrugCentral uuid:ec67b7d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ec67e07c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4D2 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ec680908-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ec683252-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NCG7 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ec685aca-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95870 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Abhydrolase domain-containing protein 16A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ec68836a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N2K0 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Monoacylglycerol lipase ABHD12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ec68abec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13093 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Platelet-activating factor acetylhydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ec68d52c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00591 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ec68fd90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BV23 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Monoacylglycerol lipase ABHD6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:ec69263a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6WQJ1 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec694ebc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Lipoprotein lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.18']} DrugCentral uuid:ec697842-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11150 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Hepatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:ec69a0d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5X9 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat targets Enzyme (Endothelial lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ec69c96e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16233 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat is inhibitor of Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.9']} DrugCentral uuid:ec69f218-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07098 biolink:molecularly_interacts_with DrugCentral:1996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orlistat is inhibitor of Enzyme (Gastric triacylglycerol lipase) DrugCentral uuid:ec6a190a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.886']} DrugCentral uuid:ec6a4466-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.092']} DrugCentral uuid:ec6a70da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.174']} DrugCentral uuid:ec6a9ace-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.614']} DrugCentral uuid:ec6ac396-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.578']} DrugCentral uuid:ec6aec40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.903']} DrugCentral uuid:ec6b14e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.666']} DrugCentral uuid:ec6b3df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.553']} DrugCentral uuid:ec6b668e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.283']} DrugCentral uuid:ec6b8f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:ec6bb7c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:ec6be1e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.165']} DrugCentral uuid:ec6c0a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:ec6c3316-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.873']} DrugCentral uuid:ec6c5bc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:ec6c8500-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ec6cad96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:ec6cd640-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.889']} DrugCentral uuid:ec6cfeea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:ec6d291a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.764']} DrugCentral uuid:ec6d51b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:ec6d7a50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.201']} DrugCentral uuid:ec6da2dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ec6dcf14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:ec6e0f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ec6e0f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ec6e0f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ec6e0f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ec6e0f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ec6e0f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ec6e0f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ec6e7d38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06818 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.83']} DrugCentral uuid:ec6ea59c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16207 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ec6ecebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ec6ef7b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:ec6f2044-ac81-11ec-8b6b-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:ec6f48d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ec6f715c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75VQ4 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.81']} DrugCentral uuid:ec6f9ba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6Q793 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:ec6fc42c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ec6feccc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2LFS1 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ec701562-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4LRQ6 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:ec703eac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q20MD3 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:ec706710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:ec708f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ec70b86e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03469 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.86']} DrugCentral uuid:ec70e10e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07599 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec710990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.96']} DrugCentral uuid:ec71321c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XV28 biolink:molecularly_interacts_with DrugCentral:2001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ec715bac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11172 biolink:molecularly_interacts_with DrugCentral:2002 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oteracil is inhibitor of Enzyme (Uridine 5'-monophosphate synthase) DrugCentral uuid:ec71801e-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ouabain targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.169']} DrugCentral uuid:ec71a8a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ouabain targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.009']} DrugCentral uuid:ec71d136-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ouabain targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:ec71f724-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:2004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ouabain targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:ec721f9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxacillin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ec724814-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxacillin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:ec727096-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:ec729670-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxacillin targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ec72ce6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ec72ce6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ec72ce6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ec72ce6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ec72ce6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:ec731a1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxametacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ec7345a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxametacin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ec7374c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxametacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ec7374c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxametacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ec73a8b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2011 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxandrolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:ec73cdba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxaprozin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:ec73f664-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxaprozin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.068']} DrugCentral uuid:ec741ee6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxaprozin targets GPCR (fMet-Leu-Phe receptor) DrugCentral uuid:ec744362-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxaprozin is inhibitor of Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ec746cca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxaprozin targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ec749556-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxaprozin targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ec74bdf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxaprozin targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:ec74e66e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxatomide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.056']} DrugCentral uuid:ec751134-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxatomide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.148']} DrugCentral uuid:ec753a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxatomide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:ec75630a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxatomide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:ec758baa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxatomide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec75b5d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxatomide is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:ec75e636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:ec75e636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:ec75e636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:ec762542-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2017 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxcarbazepine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:ec764a18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2026 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyphencyclimine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:ec766e94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2026 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyphencyclimine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:ec769306-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxprenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ec76bbb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxprenolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ec76e590-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxprenolol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ec770df4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:ec77368a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.991']} DrugCentral uuid:ec775f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.589']} DrugCentral uuid:ec778892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.298']} DrugCentral uuid:ec77b240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.837']} DrugCentral uuid:ec77dafe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:ec780394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:ec782cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:ec78552e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.168']} DrugCentral uuid:ec787dc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:ec78a75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:ec78d03a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:ec78f8ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:ec792184-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:ec794ad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ec7974a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2028 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:ec799d1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:ec79c652-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ec79ef2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ec7a17b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ec7a4046-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ec7a68e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ec7a9406-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:ec7abcb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:ec7ae532-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:ec7b0ddc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ec7b3712-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2029 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:ec7b5fc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:ec7b887a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.493']} DrugCentral uuid:ec7bb17e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ec7bda0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:ec7c02a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ec7c2b4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.111']} DrugCentral uuid:ec7c54c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.342']} DrugCentral uuid:ec7c7d5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.019']} DrugCentral uuid:ec7ca5f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:ec7cce9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ec7cf7e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ec7d207c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:ec7d4908-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ec7d7298-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ec7d9ba6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.379']} DrugCentral uuid:ec7dc568-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:ec7dee12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.162']} DrugCentral uuid:ec7e16da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.041']} DrugCentral uuid:ec7e41dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:ec7e6a7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ec7e9326-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:ec7ebba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:ec7ee506-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:ec7f0d9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ec7f3632-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:ec7f66fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:ec7f66fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:ec7f66fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:ec7fae0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:ec7fae0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:ec7fae0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:ec7fed34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:ec80199e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ec804220-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2033 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetholone targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:ec8066a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2033 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetholone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:ec808b04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2033 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymetholone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:ec80b444-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:ec80dce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:ec8105ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ec812f82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:ec81580e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ec8180ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.27']} DrugCentral uuid:ec81a93a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ec81d306-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ec81fbb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:ec822446-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:ec82588a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:ec82588a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:ec82588a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:ec82588a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:ec82a75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:ec82a75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxymorphone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:ec82dc56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2036 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyphenbutazone targets GPCR (fMet-Leu-Phe receptor) DrugCentral uuid:ec8300be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16647 biolink:molecularly_interacts_with DrugCentral:2036 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyphenbutazone targets Enzyme (Prostacyclin synthase) DrugCentral uuid:ec83299a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2036 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyphenbutazone is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:ec83299a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2036 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyphenbutazone is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:ec835802-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2036 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyphenbutazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:ec8380a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:ec83a640-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:ec83cd46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.84']} DrugCentral uuid:ec83f8ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:2041 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxytetracycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:ec841d78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:2041 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxytetracycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:ec84428a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxytocin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:ec846aee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxytocin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:ec849366-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:2042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxytocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ec84bbfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:2042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxytocin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ec84e4ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01178 biolink:molecularly_interacts_with DrugCentral:2042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxytocin targets Secreted (Oxytocin-neurophysin 1) DrugCentral uuid:ec850a3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:2042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxytocin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:ec8532c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:2042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxytocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:ec855b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:2042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxytocin is agonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ec8585fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ozagrel targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ec85b1d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49430 biolink:molecularly_interacts_with DrugCentral:2043 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ozagrel targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ec85ddb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ec86082c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ec863126-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:ec8659b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets Transporter (Bile salt export pump) DrugCentral uuid:ec867e2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:ec86a296-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07437 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is inhibitor of Structural (Tubulin beta chain) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec86cbfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.621']} DrugCentral uuid:ec86f49e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.954']} DrugCentral uuid:ec871d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.643']} DrugCentral uuid:ec8745b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:ec8771da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.794']} DrugCentral uuid:ec879aac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ec87c32e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:ec87ec8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13509 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets Structural (Tubulin beta-3 chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ec88152c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel targets Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ec885c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec885c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec885c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec885c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec885c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec885c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec885c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec885c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec885c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ec88e1f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:2045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palmidrol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ec890a72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:2045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palmidrol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ec89351a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:2045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palmidrol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ec895d88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:2045 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palmidrol is agonist of GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ec89860a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palonosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.5']} DrugCentral uuid:ec89b274-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palonosetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:ec89b274-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palonosetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:ec89e712-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:2047 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pamabrom targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:ec8a0fc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pamidronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:ec8a3852-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pamidronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ec8a6142-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07010 biolink:molecularly_interacts_with DrugCentral:2048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pamidronic acid targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ec8a89c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2049 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobenzoic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ec8ab25a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2049 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobenzoic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:ec8adadc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2049 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobenzoic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:ec8b049e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2049 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobenzoic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ec8b2d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q81VW8 biolink:molecularly_interacts_with DrugCentral:2049 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobenzoic acid targets Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:ec8b55de-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2049 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminobenzoic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ec8b7ea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WNC6 biolink:molecularly_interacts_with DrugCentral:2050 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminosalicylic acid targets Kinase (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase) DrugCentral uuid:ec8ba386-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2050 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminosalicylic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['2.92']} DrugCentral uuid:ec8bcffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2050 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminosalicylic acid is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:ec8bcffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2050 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aminosalicylic acid is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:ec8c0628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:ec8c0628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:ec8c0628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:ec8c4b56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ec8c4b56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ec8c8ae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ec8c8ae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ec8c8ae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ec8c8ae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ec8cd77e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:ec8cfbe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:ec8d2490-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ec8d4d30-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ec8d765c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ec8d9ee8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:ec8dcb5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:ec8dcb5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:ec8df9ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:ec8e26ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec8e26ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:2054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pantoprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec8e5aae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:ec8e833a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:ec8ead88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:ec8ed24a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:ec8efac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:ec8f2344-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ec8f4c5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.118']} DrugCentral uuid:ec8f75d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.088']} DrugCentral uuid:ec8f9e64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ec8fc6f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ec8fefcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:ec901876-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM07 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Protein-arginine deiminase type-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:ec904102-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:ec906984-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ec90956c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ec90c028-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QYJ6 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:ec90f07a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ec90f07a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ec90f07a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ec913454-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:ec913454-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:ec916ff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ec916ff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ec916ff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ec91af7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ec91d864-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2056 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ec9208c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:ec9208c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:ec9208c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:ec92424a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 parecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.854']} DrugCentral uuid:ec926dd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 parecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:ec92966e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2065 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pargyline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ec92c2ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2065 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pargyline is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ec92ebfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2065 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pargyline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ec931486-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2065 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pargyline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ec933d08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11884 biolink:molecularly_interacts_with DrugCentral:2065 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pargyline targets Enzyme (Aldehyde dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:ec936576-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paricalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ec938e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ec93b6de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.647']} DrugCentral uuid:ec93df6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.068']} DrugCentral uuid:ec9407ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:ec943244-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.398']} DrugCentral uuid:ec945ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.52']} DrugCentral uuid:ec948320-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ec94abc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:ec94d4f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.724']} DrugCentral uuid:ec94fd8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ec952a5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:ec95534a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:ec957be0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:ec95a46c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ec95ccc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec95f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ec961f50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec9647c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25098 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:ec967388-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:ec969d5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:ec96c6e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:ec96ef70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.36']} DrugCentral uuid:ec971806-ac81-11ec-8b6b-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ec974100-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:ec9769a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ec9792ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ec97c2ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ec97c2ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ec97c2ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ec980c66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ec980c66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ec980c66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ec984bc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:ec987502-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:ec989d7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21146 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ec98c5f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:ec98ee6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:2071 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pefloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.785']} DrugCentral uuid:ec991750-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2071 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pefloxacin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.097']} DrugCentral uuid:ec993fc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2071 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pefloxacin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.785']} DrugCentral uuid:ec99682c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed is inhibitor of Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.468']} DrugCentral uuid:ec9990c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.181']} DrugCentral uuid:ec99bb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:ec99dfbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ec9a0840-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Serine hydroxymethyltransferase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ec9a30d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ec9a5a0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:ec9a8392-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:ec9aac28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ec9ad518-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ec9afd9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ec9b261c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45352 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ec9b4e9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:ec9b7838-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ec9ba0ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ec9bc946-ac81-11ec-8b6b-0242ac110002 UniProtKB:E2QDN0 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:ec9bf1b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.86']} DrugCentral uuid:ec9c1aea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:ec9c4376-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q64737 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed is inhibitor of Enzyme (Trifunctional purine biosynthetic protein adenosine-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:ec9c6c20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22102 biolink:molecularly_interacts_with DrugCentral:2073 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemetrexed is inhibitor of Enzyme (Trifunctional purine biosynthetic protein adenosine-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ec9c94ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2075 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemoline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:ec9cbd9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2078 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penbutolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ec9ce63c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2078 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penbutolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ec9d0ec8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2078 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penbutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ec9d374a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02763 biolink:molecularly_interacts_with DrugCentral:2078 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penbutolol targets Secreted (Alpha-1-acid glycoprotein 1) DrugCentral uuid:ec9d5e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2078 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penbutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:ec9d8876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2079 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:ec9dad60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:2079 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penciclovir targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ec9dd5ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:2079 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penciclovir targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ec9dfee6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ec9e2772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:ec9e501c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ec9e78bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:ec9ea2b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ec9ecb50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ec9ef3dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:ec9f1db2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ec9f46ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ec9f6f56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:ec9f97f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ec9fc140-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ec9fe9d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:eca01280-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:eca03b34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:eca0642e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:eca08cce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:eca0b564-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:eca0de0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:eca108ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:eca13160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:eca16950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:eca16950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:eca16950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:eca16950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:eca16950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:eca1c008-ac81-11ec-8b6b-0242ac110002 UniProtKB:P44514 biolink:molecularly_interacts_with DrugCentral:2081 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 penicillamine targets Enzyme (Succinyl-diaminopimelate desuccinylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eca1e88a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:eca20ce8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:eca235ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eca276a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca276a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca276a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca276a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca276a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca276a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca276a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca2d9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eca302a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxymethylpenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:eca33e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca33e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca33e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca33e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca33e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca33e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca33e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eca39ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:2088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:eca3c754-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentagastrin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:eca3efe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:2088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:eca418b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:2088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eca44148-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.287']} DrugCentral uuid:eca469de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:eca49274-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:eca4bdee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:eca4e698-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.765']} DrugCentral uuid:eca50f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.867']} DrugCentral uuid:eca53878-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.295']} DrugCentral uuid:eca560fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:eca58a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.683']} DrugCentral uuid:eca5b30c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eca5dbf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:eca60492-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.101']} DrugCentral uuid:eca62d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eca6556e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:eca67eae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:eca6a730-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:eca6cfb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04271 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Cytosolic other (Protein S100-B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:eca6f852-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:eca72174-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:eca749e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19801 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Amiloride-sensitive amine oxidase [copper-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:eca773a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:eca79c44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eca7c548-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eca7edc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:eca8164c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:eca83f5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:eca87f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:eca87f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:eca87f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:eca87f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:eca87f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:eca87f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:eca87f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:eca8f0e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:eca8f0e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:eca92532-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21673 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Spermidine/spermine N(1)-acetyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:eca94daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75365 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Protein-tyrosine phosphatase 4A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:eca9762c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:eca99f1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04631 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Unclassified (Protein S100-B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.36']} DrugCentral uuid:eca9c7b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:eca9f048-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ecaa199c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12974 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Protein tyrosine phosphatase type IVA 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ecaa4228-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q93096 biolink:molecularly_interacts_with DrugCentral:2090 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentamidine targets Enzyme (Protein tyrosine phosphatase type IVA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ecaa6abe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:ecaa932c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.553']} DrugCentral uuid:ecaac41e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:ecaac41e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:ecaac41e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecab3cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ecac1e68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ecac1e68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ecac1e68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ecac5db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:2096 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentolonium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:ecac86c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2096 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentolonium is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:ecac86c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2096 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentolonium is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:ecacb526-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:2098 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentostatin is inhibitor of Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.8']} DrugCentral uuid:ecacdd9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56658 biolink:molecularly_interacts_with DrugCentral:2098 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentostatin targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:ecad0666-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2099 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxifylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ecad2f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:2099 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxifylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:ecad53d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2099 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxifylline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:ecad7c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2099 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentoxifylline is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) DrugCentral uuid:ecada0bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ecadcace-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ecadf3dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:ecae1c68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ecae44e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:ecae6dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ecae9648-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:ecaebfba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:ecaee850-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ecaf1154-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ecaf39d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:ecaf6262-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ecaf8ada-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ecafb6d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ecafe016-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:ecb00898-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:ecb03264-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:ecb05b04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:ecb08386-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.838']} DrugCentral uuid:ecb0ad48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:ecb0d638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:ecb0fec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ecb12746-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ecb14fbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ecb179a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:ecb1a23e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:ecb1cac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ecb1fb1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:ecb1fb1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:ecb1fb1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:ecb23f00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:ecb23f00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:ecb2823a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:ecb2823a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:ecb2823a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:ecb2823a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:ecb2823a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:ecb2dd84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:ecb2dd84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:ecb31182-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ecb339fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pergolide is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ecb3668c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.962']} DrugCentral uuid:ecb390ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:ecb3b98e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.486']} DrugCentral uuid:ecb3e2d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:ecb40b78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:ecb43418-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ecb45ca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.105']} DrugCentral uuid:ecb485bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.027']} DrugCentral uuid:ecb4ae34-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:ecb4d29c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:ecb4fb3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) DrugCentral uuid:ecb5209e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50416 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 1, liver isoform) DrugCentral uuid:ecb54506-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23786 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:ecb56d9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.828']} DrugCentral uuid:ecb59614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.391']} DrugCentral uuid:ecb5c062-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ecb5f0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ecb5f0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ecb5f0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ecb630ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18886 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Enzyme (Carnitine palmitoyltransferase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ecb65a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32198 biolink:molecularly_interacts_with DrugCentral:2106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perhexiline targets Enzyme (Carnitine palmitoyltransferase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:ecb68312-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2107 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 periciazine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ecb6abb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2107 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 periciazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ecb6d43e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2107 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 periciazine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ecb6fe78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2107 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 periciazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:ecb726fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2108 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perindopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ecb74f68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perlapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:ecb777e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perlapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.704']} DrugCentral uuid:ecb7a0da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perlapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.824']} DrugCentral uuid:ecb7c970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perlapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ecb7f1e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perlapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:ecb81a60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perlapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:ecb843b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perlapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ecb86c4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perospirone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ecb894f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perospirone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:ecb8be5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perospirone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:ecb8e706-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perospirone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:ecb90f9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:ecb93832-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ecb96122-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.462']} DrugCentral uuid:ecb989c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:ecb9b23a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:ecb9dbc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:ecba04ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:ecba2d78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:ecba560e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ecba7e9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:ecbaa87a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.521']} DrugCentral uuid:ecbad11a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.088']} DrugCentral uuid:ecbaf992-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.733']} DrugCentral uuid:ecbb221e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.481']} DrugCentral uuid:ecbb4adc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:ecbb7368-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.588']} DrugCentral uuid:ecbb9d2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ecbbc5ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ecbbef14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perphenazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ecbc17aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenacemide is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:ecbc3c08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenacetin targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:ecbc6070-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ecbc89f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ecbcb2aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazocine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ecbcdb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ecbd0426-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:2119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:ecbd4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ecbd4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ecbd4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ecbd4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ecbd4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ecbd4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ecbd4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ecbd4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ecbd4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ecbd4f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ecbdce60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P83512 biolink:molecularly_interacts_with DrugCentral:2120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenazopyridine targets Enzyme (Snake venom metalloproteinase Bap1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:ecbdf778-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ecbe2022-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:ecbe4976-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:ecbe7216-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ecbe9aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ecbec34c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ecbeec50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ecbf2be8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ecbf2be8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ecbf2be8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ecbf2be8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ecbf2be8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ecbf2be8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ecbf2be8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ecbfaffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ecbfaffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ecbfaffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ecbfaffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ecbfaffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ecbfaffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ecbfaffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ecc02390-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ecc02390-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ecc05b3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ecc05b3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ecc09e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ecc09e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ecc09e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ecc09e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ecc09e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ecc0f478-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phendimetrazine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:ecc118d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phendimetrazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ecc14162-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phendimetrazine is inhibitor of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:ecc16692-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:ecc18f0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.076']} DrugCentral uuid:ecc1b7b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ecc1e036-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine is inhibitor of Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:ecc20c46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:ecc234d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ecc25d7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.836']} DrugCentral uuid:ecc2866c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:ecc2aeee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16853 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ecc2d752-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ecc2ffd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:ecc328ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ecc35146-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:ecc37afe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenelzine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ecc3a358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y478 biolink:molecularly_interacts_with DrugCentral:2126 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenformin targets Kinase (5'-AMP-activated protein kinase subunit beta-1) DrugCentral uuid:ecc3c978-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2129 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenindamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ecc3f222-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2130 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenindione is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) DrugCentral uuid:ecc41676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2130 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenindione targets Enzyme (Prothrombin) DrugCentral uuid:ecc43ad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2130 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ecc463c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2131 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pheniprazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:ecc48958-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2131 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pheniprazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:ecc4adde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pheniramine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:ecc4d246-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pheniramine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:ecc50356-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:ecc50356-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:ecc50356-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:ecc5428a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenmetrazine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.298']} DrugCentral uuid:ecc56b2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenmetrazine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.883']} DrugCentral uuid:ecc594f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenmetrazine targets Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:ecc5bc42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenobarbital targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:ecc5e118-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenobarbital targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:ecc60d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ecc60d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ecc60d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ecc64db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ecc64db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ecc64db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ecc68cda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2135 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ecc6b566-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2135 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ecc6deb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2135 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ecc70868-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q834R3 biolink:molecularly_interacts_with DrugCentral:2135 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ecc73108-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ecc759b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:ecc7840a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.456']} DrugCentral uuid:ecc7acc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ecc7e4a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ecc7e4a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ecc7e4a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ecc7e4a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ecc7e4a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ecc84264-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:ecc84264-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:ecc84264-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:ecc8895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:ecc8895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:ecc8895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:ecc8ca4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenprocoumon targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ecc8f2d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:2138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenprocoumon targets Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ecc91b80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:2138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenprocoumon targets Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ecc9454c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenprocoumon is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.745']} DrugCentral uuid:ecc975bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:ecc975bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:ecc975bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:ecc9ae74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2140 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentermine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:ecc9d340-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2140 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentermine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.801']} DrugCentral uuid:ecc9fcd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:ecca2584-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:ecca4dfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.784']} DrugCentral uuid:ecca7728-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.667']} DrugCentral uuid:ecca9f96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:eccac82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.616']} DrugCentral uuid:eccaf0ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.684']} DrugCentral uuid:eccb1b2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:eccb43e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:eccb6c78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:eccb9518-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:eccbbe3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:eccbe6c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.71']} DrugCentral uuid:eccc0f8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:eccc3824-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.94']} DrugCentral uuid:eccc6146-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:eccc89c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ecccb240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:ecccdac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:eccd05ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:eccd2e3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:eccd56aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.03']} DrugCentral uuid:eccd7f9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:eccdafd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:eccdafd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:eccdafd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:eccdf812-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:eccdf812-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:eccdf812-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:ecce3912-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylalanine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:ecce6194-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08532 biolink:molecularly_interacts_with DrugCentral:2144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylalanine targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ecce8a34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:2144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylalanine targets Transporter (L-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:ecceb36a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19111 biolink:molecularly_interacts_with DrugCentral:2144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylalanine targets Enzyme (Intestinal alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:eccedd5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6DWJ6 biolink:molecularly_interacts_with DrugCentral:2144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylalanine is agonist of GPCR (Probable G-protein coupled receptor 139) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:eccf05e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09923 biolink:molecularly_interacts_with DrugCentral:2144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylalanine targets Enzyme (Intestinal-type alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:eccf2f48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P98170 biolink:molecularly_interacts_with DrugCentral:2144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylalanine targets Unclassified (E3 ubiquitin-protein ligase XIAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:eccf582e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutazone is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:eccf80ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutazone targets GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:eccfa91e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16647 biolink:molecularly_interacts_with DrugCentral:2145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutazone targets Enzyme (Prostacyclin synthase) DrugCentral uuid:eccfcd86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutazone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:eccff6a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8SPQ9 biolink:molecularly_interacts_with DrugCentral:2145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase 2; Prostaglandin G/H synthase-2; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ecd02326-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ecd02326-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ecd056f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2145 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylbutazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:ecd07f9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ecd0abc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ecd0d488-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ecd0fd32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ecd1262c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ecd14eae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ecd18018-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:ecd18018-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:ecd18018-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:ecd1c802-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ecd1c802-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ecd1c802-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ecd20f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ecd20f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ecd20f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ecd24e1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:2146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ecd27982-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:ecd2a47a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:ecd2c8ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:ecd2f164-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:ecd31a68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:ecd33fca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:ecd36856-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:ecd390ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:ecd3ba36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.166']} DrugCentral uuid:ecd3e2cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:ecd40b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:ecd434f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ecd45fc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylpropanolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:ecd4883a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenyltoloxamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:ecd4b0bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenyltoloxamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:ecd4daa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenyltoloxamine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:ecd50346-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenyltoloxamine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:ecd52be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenyltoloxamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:ecd55044-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:ecd57538-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:ecd59a2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:ecd5be94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ecd5e720-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:ecd60ce6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:ecd63590-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:ecd65a16-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:ecd67e92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:ecd6af5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ecd6af5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ecd6af5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ecd6eeae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phloroglucinol targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:ecd71b18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2156 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ecd71b18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2156 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ecd7577c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ecd7577c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ecd7577c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ecd796ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:ecd7bfbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.37']} DrugCentral uuid:ecd7e9e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ecd8127a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ecd83ad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.17']} DrugCentral uuid:ecd8645a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:ecd88e44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.17']} DrugCentral uuid:ecd8b6bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:ecd8df66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ecd907fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:ecd9311e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:ecd959a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ecd9822c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:ecd9aab8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36196 biolink:molecularly_interacts_with DrugCentral:2159 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ecd9d6a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ecda01fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ecda2c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ecda54e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdab700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ecdb8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotin targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ecdbb434-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotin is blocker of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ecdbdcd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotin is blocker of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ecdc05ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:2163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picrotin targets Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ecdc2ed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2165 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:ecdc533a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2165 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:ecdc77b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:ecdca056-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ecdcc996-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ecdcf204-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ecdd2b5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:ecdd2b5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:ecdd2b5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:ecdd2b5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:ecdd2b5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:ecdd84bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:ecddad52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:ecddd5ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ecddfea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ecde2732-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ecde4fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2167 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilsicainide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:ecde7958-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2167 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pilsicainide is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.377']} DrugCentral uuid:ecdea27a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:2168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimecrolimus targets Cytokine (Interleukin-5) DrugCentral uuid:ecdec6ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:2168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimecrolimus targets Cytokine (Interferon gamma) DrugCentral uuid:ecdeeb36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimecrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ecdf13c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P60568 biolink:molecularly_interacts_with DrugCentral:2168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimecrolimus targets Cytokine (Interleukin-2) DrugCentral uuid:ecdf3992-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48454 biolink:molecularly_interacts_with DrugCentral:2168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimecrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform) DrugCentral uuid:ecdf5e22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62658 biolink:molecularly_interacts_with DrugCentral:2168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimecrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ecdf86b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimethixene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:ecdfaf58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimethixene targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:ecdfd85c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WTS6 biolink:molecularly_interacts_with DrugCentral:2169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimethixene targets Enzyme (Histone-lysine N-methyltransferase SETD7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:ece000f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:2171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimobendan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ece02d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimobendan is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:ece02d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimobendan is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:ece06150-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:ece08a5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.862']} DrugCentral uuid:ece0b2ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.798']} DrugCentral uuid:ece0db9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.842']} DrugCentral uuid:ece1054c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:ece12e50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:ece156c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.63']} DrugCentral uuid:ece17f86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.559']} DrugCentral uuid:ece1a8c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.058']} DrugCentral uuid:ece1d15c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.149']} DrugCentral uuid:ece1f9e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.301']} DrugCentral uuid:ece22274-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.704']} DrugCentral uuid:ece24be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:ece2765c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:ece29efc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:ece2c7a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ece2f1c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.709']} DrugCentral uuid:ece31a44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:ece342d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.424']} DrugCentral uuid:ece36b66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:ece394ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ece3bd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ece3e5be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ece40e40-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ece43ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:ece43ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:ece43ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:ece47df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ece4a684-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ece4d294-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:ece4fb16-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ece523ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ece54cf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ece57582-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ece59e04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ece5c6b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:ece5ff02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ece5ff02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ece5ff02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ece5ff02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ece5ff02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ece655e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94782 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide targets Enzyme (Ubiquitin carboxyl-terminal hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ece67e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EQ60 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ece6aa92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:ece6d36e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O54898 biolink:molecularly_interacts_with DrugCentral:2172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ece6fbf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60706 biolink:molecularly_interacts_with DrugCentral:2173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pinacidil targets Ion channel (ATP-binding cassette sub-family C member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:ece724fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:2173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pinacidil targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:ece74d62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pinacidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:ece74d62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pinacidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:ece78160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol is partial agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ece7a9ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol is partial agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ece7d444-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ece7fcda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ece82584-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ece84e24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:ece87a0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.78']} DrugCentral uuid:ece8a55e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ece8d0e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.209']} DrugCentral uuid:ece8faae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ece9234e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ece95800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ece95800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ece95800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ece95800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ece9afee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ece9afee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ece9afee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ece9ef36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.943']} DrugCentral uuid:ecea17b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ecea429c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ecea6e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.455']} DrugCentral uuid:ecea96a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:eceabf24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:eceae86e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.879']} DrugCentral uuid:eceb10e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:eceb397c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:eceb6258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37238 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:eceb8af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O88275 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:ecebb38e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ecebdbfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ecec05c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:ecec3160-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0K020 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ecec5ce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:ecec85ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N5K1 biolink:molecularly_interacts_with DrugCentral:2179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:ececaed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:ececd75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.87']} DrugCentral uuid:ececfffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:eced2980-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:eced5284-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.461']} DrugCentral uuid:eced7c5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.351']} DrugCentral uuid:eceda504-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.992']} DrugCentral uuid:ecedcd90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.256']} DrugCentral uuid:ecedf73e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:ecee1fca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:ecee4888-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:ecee71dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.105']} DrugCentral uuid:ecee9d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.799']} DrugCentral uuid:eceec5ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.939']} DrugCentral uuid:eceeeed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:ecef17b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.189']} DrugCentral uuid:ecef4058-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ecef68d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:ecef915c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.848']} DrugCentral uuid:ecefbbd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:ecefe468-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.429']} DrugCentral uuid:ecf00d08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:ecf03576-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:ecf05eac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ecf0871a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ecf0afa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:ecf0d83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:ecf1015e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ecf12ae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ecf1538e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.324']} DrugCentral uuid:ecf17c92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.644']} DrugCentral uuid:ecf1a618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:ecf1ceae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.602']} DrugCentral uuid:ecf1f758-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ecf2208e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ecf2492e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ecf271ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:ecf29a50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ecf2c37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ecf2efd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:ecf2efd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:ecf3260a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:ecf3260a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:ecf3260a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:ecf3657a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:ecf3657a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:ecf398ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:ecf398ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:ecf3c722-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:ecf3eb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:2187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ecf41470-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:2187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperacillin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:ecf4541c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ecf4541c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ecf4541c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ecf4541c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ecf4541c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ecf4541c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ecf4541c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:ecf4b538-ac81-11ec-8b6b-0242ac110002 UniProtKB:O18276 biolink:molecularly_interacts_with DrugCentral:2188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperazine targets Ion channel (Gamma-aminobutyric acid receptor subunit beta) DrugCentral uuid:ecf4d9a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipotiazine palmitate is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:ecf50236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2193 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pipotiazine palmitate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.553']} DrugCentral uuid:ecf52c20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2199 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirbuterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:ecf55092-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:ecf57928-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:ecf5a1d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:ecf5cacc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:ecf5f36c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:ecf61c02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:ecf644a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ecf66e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:ecf696e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:ecf6bf86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:ecf6e81c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ecf71328-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ecf73be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ecf773d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ecf773d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ecf773d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ecf773d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ecf773d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ecf7da6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:ecf7da6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:ecf7da6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:ecf7da6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:ecf7da6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:ecf83136-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piretanide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ecf85a62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:2201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piretanide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ecf882d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ecf8ab84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ecf8d528-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ecf8ffd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ecf9285c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:ecf950f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ecf979e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ecf9a282-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ecf9cb18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ecf9f3ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ecfa1d5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piribedil is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ecfa461a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:2206 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:ecfa6e92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28347 biolink:molecularly_interacts_with DrugCentral:2206 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ecfa973c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:2206 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:ecfac144-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15562 biolink:molecularly_interacts_with DrugCentral:2206 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:ecfae9d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99594 biolink:molecularly_interacts_with DrugCentral:2206 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:ecfb1266-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2206 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirlindole is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:ecfb3ade-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2207 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirmenol targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:ecfb5fa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piroxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ecfb8854-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piroxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:ecfbb0d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piroxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:ecfbdef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:ecfbdef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:ecfc16b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ecfc16b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ecfc4a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2213 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirprofen targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:ecfc6ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2213 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pirprofen targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:ecfc9654-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitavastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.168']} DrugCentral uuid:ecfcc28c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitavastatin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:ecfceb2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitavastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:ecfd1534-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pizotifen targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:ecfd3de8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pizotifen is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ecfd6674-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:ecfd8f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ecfdb886-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:ecfde126-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ecfe09c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pizotifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ecfe3270-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polythiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['9.09']} DrugCentral uuid:ecfe5cb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralidoxime is activator of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.59']} DrugCentral uuid:ecfe85e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08725 biolink:molecularly_interacts_with DrugCentral:2232 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralmorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ecfeae6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92847 biolink:molecularly_interacts_with DrugCentral:2232 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralmorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) DrugCentral uuid:ecfed2d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:ecfefbe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ecff245a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.121']} DrugCentral uuid:ecff4cfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:ecff7590-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:ecff9e94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.925']} DrugCentral uuid:ecffc810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ecfff09c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.668']} DrugCentral uuid:ed00190a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:ed004326-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.455']} DrugCentral uuid:ed006ba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:ed00943e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.282']} DrugCentral uuid:ed00bcfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:ed00e5ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:ed010e82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ed013718-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramipexole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:ed01645e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2236 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:ed01645e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2236 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:ed019c30-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2236 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:ed019c30-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2236 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:ed01d3da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2236 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:ed01d3da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2236 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:ed0208e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2237 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pranlukast targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ed023168-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2237 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pranlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ed0259d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:2237 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pranlukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ed028262-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2237 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pranlukast targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ed02ac74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:2237 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pranlukast targets GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:ed02d5a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2237 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pranlukast targets Nuclear other (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ed02fe0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:2237 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pranlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:ed03269a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2238 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pranoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ed034fe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2238 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pranoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ed03796a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pravastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ed03a20a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pravastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:ed03ca96-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:2239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pravastatin targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:ed03fb9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ed03fb9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ed03fb9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ed0433c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 praziquantel targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:ed045c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08515 biolink:molecularly_interacts_with DrugCentral:2241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 praziquantel targets Enzyme (Glutathione S-transferase class-mu 26 kDa isozyme) DrugCentral uuid:ed048120-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95US7 biolink:molecularly_interacts_with DrugCentral:2241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 praziquantel is blocker of Ion channel (High voltage-activated calcium channel beta subunit CavB1) DrugCentral uuid:ed04a5a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q962H3 biolink:molecularly_interacts_with DrugCentral:2241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 praziquantel is blocker of Ion channel (High voltage-activated calcium channel beta subunit CavB2) DrugCentral uuid:ed04ca40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2243 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednicarbate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:ed04eec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ed0517d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Cytosolic other (Annexin A1) DrugCentral uuid:ed053c32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:ed0564e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ed058d7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ed05b856-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:ed05e15a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:ed0609fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ed063290-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:ed065b9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15104 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Enzyme (Glutamine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:ed068416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:ed06ac98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:ed06d51a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78536 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Unclassified (Disintegrin and metalloproteinase domain-containing protein 17) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:ed06fe46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ed0726e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2247 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:ed074c98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.28']} DrugCentral uuid:ed0775ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:ed079ec8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ed07c75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ed07f06c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:ed0819c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:ed084378-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ed086c04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:ed0894ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15104 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Enzyme (Glutamine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ed08bd80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:ed08e620-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:ed090ede-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78536 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Unclassified (Disintegrin and metalloproteinase domain-containing protein 17) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:ed093760-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ed0961d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2253 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisone targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.772']} DrugCentral uuid:ed098a76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2253 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ed09b2da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2253 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisone targets Cytosolic other (Annexin A1) DrugCentral uuid:ed09d738-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pregabalin targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.801']} DrugCentral uuid:ed0a008c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:2255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pregabalin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:ed0a292c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O77773 biolink:molecularly_interacts_with DrugCentral:2255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pregabalin targets Ion channel (Uncharacterized protein; Voltage-dependent calcium channel alpha-2 delta subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:ed0a51cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:2255 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pregabalin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:ed0a7a58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pregnenolone succinate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:ed0aa35c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pregnenolone succinate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ed0acbfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pregnenolone succinate targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:ed0af46a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prenalterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ed0b1e04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prenalterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.97']} DrugCentral uuid:ed0b514e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ed0b514e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ed0b514e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ed0b9848-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:ed0b9848-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:ed0b9848-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:ed0bd876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prenylamine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ed0c00f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2263 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:ed0c2984-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2263 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ed0c5210-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2263 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.194']} DrugCentral uuid:ed0c7b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2263 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:ed0ca38c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2263 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.799']} DrugCentral uuid:ed0cd3f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:ed0cd3f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:ed0cd3f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:ed0d15d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.668']} DrugCentral uuid:ed0d3e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.075']} DrugCentral uuid:ed0d66fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:ed0d8ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:ed0db5ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ed0dde78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.739']} DrugCentral uuid:ed0e070e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:ed0e2fea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:ed0e5452-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:ed0e7dd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ed0ea66e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35869 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Transcription factor (Aryl hydrocarbon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:ed0ed04e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:ed0efbf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:ed0f2698-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primaquine targets Unclassified (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ed0f56f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ed0f56f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ed0f56f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ed0f8ff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:2267 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 primidone is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ed0fb86a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ed0fe100-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ed100a04-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ed1032a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ed105b4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 8) DrugCentral uuid:ed107fca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 11) DrugCentral uuid:ed10a590-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ed10ce58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ed10f6f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:ed111f98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAW7 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid targets Enzyme (UDP-glucuronosyltransferase 1-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.02']} DrugCentral uuid:ed1148ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:2268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probenecid is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ed11715a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probucol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.686']} DrugCentral uuid:ed1199dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:2269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probucol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed11c268-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95477 biolink:molecularly_interacts_with DrugCentral:2269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probucol is inhibitor of Transporter (ATP-binding cassette sub-family A member 1) DrugCentral uuid:ed11e78e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:2269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probucol targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ed121100-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:2269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 probucol targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:ed123978-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.86']} DrugCentral uuid:ed1262fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.812']} DrugCentral uuid:ed128d60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ed12b5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 1) DrugCentral uuid:ed12da36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:ed12fe80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBC3 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 3B) DrugCentral uuid:ed132388-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ed136fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ed136fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ed136fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ed136fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ed136fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ed136fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ed136fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ed136fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ed136fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ed136fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:ed13ed22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.569']} DrugCentral uuid:ed141590-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procaine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.529']} DrugCentral uuid:ed143e44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:ed1464d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:2271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procaine targets Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.222']} DrugCentral uuid:ed14951a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:ed14951a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:ed14951a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:ed14d43a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2273 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procaterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:ed14fd7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2273 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procaterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ed15262e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.712']} DrugCentral uuid:ed154ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:ed15778c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.764']} DrugCentral uuid:ed15a194-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.201']} DrugCentral uuid:ed15ca48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:ed15f2fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ed161c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.207']} DrugCentral uuid:ed164810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.402']} DrugCentral uuid:ed1672fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.229']} DrugCentral uuid:ed169b94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:ed16c4de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:ed16ed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:ed17161e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:ed173ec8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.622']} DrugCentral uuid:ed1767c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.324']} DrugCentral uuid:ed179076-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.611']} DrugCentral uuid:ed17b920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.723']} DrugCentral uuid:ed17e1c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.613']} DrugCentral uuid:ed180d44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.956']} DrugCentral uuid:ed1835e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.493']} DrugCentral uuid:ed185e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:ed188710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.801']} DrugCentral uuid:ed18b0d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:ed18d95e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:ed1901ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:ed192ada-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:ed195384-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:ed197c10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:ed19a5be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.245']} DrugCentral uuid:ed19cf94-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ed19f870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:ed1a2110-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.919']} DrugCentral uuid:ed1a49b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.381']} DrugCentral uuid:ed1a72e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:ed1a9b54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:ed1ac3ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prochlorperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed1aec6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.337']} DrugCentral uuid:ed1b1570-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:ed1b3e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.907']} DrugCentral uuid:ed1b6692-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:ed1b8f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:ed1bb886-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ed1bf83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed1bf83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed1bf83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed1bf83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed1bf83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed1bf83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed1bf83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed1c6d30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:ed1c6d30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:ed1c6d30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1ce652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1df40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed1ec832-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.174']} DrugCentral uuid:ed1ef0dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ed1f1986-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:ed1f4208-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ed1f6da0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:ed1f960e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:ed1fba6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:ed1fe438-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['9.876']} DrugCentral uuid:ed200ddc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:ed203690-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.94']} DrugCentral uuid:ed205f4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35610 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Enzyme (Sterol O-acyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ed208834-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ed20b0d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:ed20d960-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:ed2101ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.441']} DrugCentral uuid:ed212cbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ed21578c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:ed218022-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:ed21a8ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ed21d310-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:ed21ff8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed21ff8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed22376a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:ed22376a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:ed226bea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ed229458-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ed22bce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ed22e566-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ed23104a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone is blocker of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ed2338b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:2279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 progesterone targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed23614e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:2281 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proglumide targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.6']} DrugCentral uuid:ed238a84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:2281 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proglumide is antagonist of GPCR (Gastrin/cholecystokinin type B receptor) DrugCentral uuid:ed23aee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0IJY2 biolink:molecularly_interacts_with DrugCentral:2282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proguanil targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:ed23d34a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O02604 biolink:molecularly_interacts_with DrugCentral:2282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proguanil targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:ed23f80c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proguanil is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:ed241c92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:2282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proguanil targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ed24456e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.909']} DrugCentral uuid:ed246e22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.704']} DrugCentral uuid:ed2496b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ed24bf6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.943']} DrugCentral uuid:ed24eaa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:ed25134a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:ed253be0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.529']} DrugCentral uuid:ed25657a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:ed258f14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.656']} DrugCentral uuid:ed25b8ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:ed25e194-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:ed260aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.226']} DrugCentral uuid:ed263338-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ed265bce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.799']} DrugCentral uuid:ed26846e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:ed26af0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.551']} DrugCentral uuid:ed26d7a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.825']} DrugCentral uuid:ed27002e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.412']} DrugCentral uuid:ed2728ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.056']} DrugCentral uuid:ed2751d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:ed277a86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:ed27a312-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.796']} DrugCentral uuid:ed27cb94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:ed27f498-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:ed281d24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.427']} DrugCentral uuid:ed2845b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ed286fd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:ed2898a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:ed28c134-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.344']} DrugCentral uuid:ed28e9de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.806']} DrugCentral uuid:ed2912ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:ed293b32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ed2963c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ed298d3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:ed29ba1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ed29ba1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ed29fd88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:ed29fd88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:ed29fd88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:ed29fd88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:ed29fd88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:ed2a5ca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ed2a5ca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ed2a5ca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ed2a9be4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ed2ac452-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promegestone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ed2aed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promegestone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ed2b1718-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:ed2b3fae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.609']} DrugCentral uuid:ed2b686c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.592']} DrugCentral uuid:ed2b91fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:ed2bba88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ed2be31e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:ed2c0baa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:ed2c368e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ed2c5f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:ed2c87ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.188']} DrugCentral uuid:ed2cb096-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.948']} DrugCentral uuid:ed2cda26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:ed2cfea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:ed2d2738-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:ed2d505a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:ed2d78fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.941']} DrugCentral uuid:ed2da186-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.823']} DrugCentral uuid:ed2dca3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.479']} DrugCentral uuid:ed2df44c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:ed2e1cec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.382']} DrugCentral uuid:ed2e4578-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.975']} DrugCentral uuid:ed2e6e22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:ed2e9726-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.292']} DrugCentral uuid:ed2ebfa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.452']} DrugCentral uuid:ed2ee82a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ed2f10d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:ed2f39ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ed2f6246-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ed2f8abe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:ed2fb336-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:ed2fde56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ed3006d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ed302f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:ed30602e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ed30602e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ed30602e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ed30a020-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ed30c9f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ed30f25a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ed311b86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP23 biolink:molecularly_interacts_with DrugCentral:2286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 promethazine targets Cytosolic other (Calmodulin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:ed31449e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pronetalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ed316d52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:ed319764-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:ed31c090-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ed31e91c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:ed320d84-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:ed32325a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:ed3256c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:ed327b3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ed32a3de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:ed32ccb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['7.056']} DrugCentral uuid:ed32f546-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.524']} DrugCentral uuid:ed331ddc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.029']} DrugCentral uuid:ed33467c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.728']} DrugCentral uuid:ed337066-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:ed339bea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:ed33c4c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:ed33ed66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:ed341642-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.498']} DrugCentral uuid:ed343ee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:ed34676e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.337']} DrugCentral uuid:ed349004-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:ed34ba2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.483']} DrugCentral uuid:ed34e2b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ed350b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed3533ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ed355eb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:ed35872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:ed35afb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.849']} DrugCentral uuid:ed35d892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ed360128-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:ed3629aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.602']} DrugCentral uuid:ed365600-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:ed365600-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propafenone targets Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:ed368b52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2293 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ed36b596-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2293 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:ed36de4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2293 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:ed3706e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2293 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.2']} DrugCentral uuid:ed37316a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proparacaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ed3759f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proparacaine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:ed3782a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proparacaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:ed37af50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ed37af50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ed37af50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ed37eeac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2296 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propentofylline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:ed381724-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (D(1A) dopamine receptor) DrugCentral uuid:ed383b8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (D(2) dopamine receptor) DrugCentral uuid:ed386210-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:ed388678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (5-hydroxytryptamine receptor 2C) DrugCentral uuid:ed38aaea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:ed38cf48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:ed38f554-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:ed391ca0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:ed39413a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:ed396598-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:ed398a46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (D(4) dopamine receptor) DrugCentral uuid:ed39aeae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiomazine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:ed39d334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propiram is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:ed39f79c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.284']} DrugCentral uuid:ed3a20a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.417']} DrugCentral uuid:ed3a4940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.031']} DrugCentral uuid:ed3a71ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:ed3a9a9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.218']} DrugCentral uuid:ed3ac460-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.005']} DrugCentral uuid:ed3aef8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:ed3b1816-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:ed3b4084-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.119']} DrugCentral uuid:ed3b69ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ed3b9250-ac81-11ec-8b6b-0242ac110002 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ed3bc2ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ed3bc2ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ed3bc2ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ed3c0b4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:ed3c0b4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:ed3c0b4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3c84f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed3d61d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:ed3d61d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:ed3d61d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:ed3da0f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.919']} DrugCentral uuid:ed3dca0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:ed3df324-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:ed3e1ba6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.913']} DrugCentral uuid:ed3e4518-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:ed3e6f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.662']} DrugCentral uuid:ed3e97f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ed3ec092-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:ed3ee90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.699']} DrugCentral uuid:ed3f1254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ed3f3ad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.197']} DrugCentral uuid:ed3f636c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:ed3f8bee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:ed3fb4d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.319']} DrugCentral uuid:ed3fdd60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:ed4005f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:ed402f9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.297']} DrugCentral uuid:ed405b82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ed40874c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.671']} DrugCentral uuid:ed40b348-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ed40dcc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:ed41056e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.01']} DrugCentral uuid:ed412df0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.05']} DrugCentral uuid:ed41569a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:ed417f80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ed41a820-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.76']} DrugCentral uuid:ed41d868-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:ed41d868-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:ed41d868-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:ed42194a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ed4241b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:ed426a58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:ed4292f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:ed42bc6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propranolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:ed42e50a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:2308 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propylthiouracil is inhibitor of Enzyme (Thyroid peroxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:ed430d96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2308 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propylthiouracil targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ed433622-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49895 biolink:molecularly_interacts_with DrugCentral:2308 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propylthiouracil is inhibitor of Enzyme (Type I iodothyronine deiodinase) DrugCentral uuid:ed435af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59533 biolink:molecularly_interacts_with DrugCentral:2308 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propylthiouracil targets GPCR (Taste receptor type 2 member 38) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ed43838e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:2309 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propyphenazone is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.481']} DrugCentral uuid:ed43abe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proquazone targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:ed43d046-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proquazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:ed43fb0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proquazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ed43fb0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proquazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ed442ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proscillaridin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.056']} DrugCentral uuid:ed445750-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proscillaridin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:ed447ba4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protionamide targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ed44a4ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:2316 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protirelin is agonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ed44cd98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:2316 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ed44f642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R297 biolink:molecularly_interacts_with DrugCentral:2316 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protirelin targets GPCR (Protein Trhr2; Thyrotropin releasing hormone receptor 2; Thyrotropin-releasing hormone receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ed451f3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21761 biolink:molecularly_interacts_with DrugCentral:2316 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ed4547dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERT1 biolink:molecularly_interacts_with DrugCentral:2316 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ed457072-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protokylol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:ed4594d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.928']} DrugCentral uuid:ed45bfdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:ed45eb7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:ed46150e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ed463d90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ed4666bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ed468f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ed46b7e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ed46e060-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ed470950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ed4731e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:ed475a86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:ed478312-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:ed47ae14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protriptyline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:ed47d696-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pseudoephedrine targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:ed47faea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pseudoephedrine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:ed481f5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pseudoephedrine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:ed48445a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pseudoephedrine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:ed4868a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrazinamide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ed489130-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrazinamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed48b9b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPB6 biolink:molecularly_interacts_with DrugCentral:2328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrazinamide targets Enzyme (Cyclopropane mycolic acid synthase 1) DrugCentral uuid:ed48de7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50575 biolink:molecularly_interacts_with DrugCentral:2328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrazinamide targets Enzyme (Amidase; Nicotinamidase; Nicotinamidase/pyrazinamidase; Pyrazinamidase; Pyrazinamidase/nicotinamidase; Pyrazinamidase/nicotinamidase PncA) DrugCentral uuid:ed4902dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:2328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrazinamide targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ed492b68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P95029 biolink:molecularly_interacts_with DrugCentral:2328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrazinamide is inhibitor of Enzyme (3-oxoacyl-ACP synthase; Fatty acid synthase Fas; Probable fatty acid synthase Fas (Fatty acid synthetase)) DrugCentral uuid:ed494fe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2330 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ed497a00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2330 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:ed49a2aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2330 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ed49cb40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2330 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:ed49f3cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.952']} DrugCentral uuid:ed4a1df2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:ed4a470a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ed4a6f96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:ed4a980e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ed4ac0fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.751']} DrugCentral uuid:ed4ae99e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.228']} DrugCentral uuid:ed4b1248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ed4b3c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:ed4b66da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:ed4b907e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:ed4bb914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:ed4be254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepyramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:ed4c0ae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.721']} DrugCentral uuid:ed4c3380-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ed4c5c02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.288']} DrugCentral uuid:ed4c8510-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.409']} DrugCentral uuid:ed4cad92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:ed4cd63c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:ed4cfebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:ed4d2a4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ed4d52ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.602']} DrugCentral uuid:ed4d7b6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ed4da3fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:ed4dcd4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:ed4df5c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.009']} DrugCentral uuid:ed4e1f60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine is inhibitor of Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ed4e4850-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q27783 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:ed4e710e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08966 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ed4e999a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K0H1 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Unclassified (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:ed4ec21c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ed4eebfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06865 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Beta-hexosaminidase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ed4f1474-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07686 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Beta-hexosaminidase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ed4f3d0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3V050 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine is inhibitor of Unclassified (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ed4f658c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:ed4f8ecc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8I1R6 biolink:molecularly_interacts_with DrugCentral:2332 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:ed4fb776-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1KRD8 biolink:molecularly_interacts_with DrugCentral:2335 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrvinium targets Unclassified (Fumarate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ed4fe098-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15056 biolink:molecularly_interacts_with DrugCentral:2335 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrvinium targets Enzyme (Synaptojanin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ed500938-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43426 biolink:molecularly_interacts_with DrugCentral:2335 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrvinium targets Enzyme (Synaptojanin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ed503232-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2335 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrvinium targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ed50627a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:ed50627a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:ed50627a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:ed50a974-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:ed50a974-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:ed50a974-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:ed50f4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:ed50f4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:ed50f4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:ed513542-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ed515f90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ed518844-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ed51b10c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.483']} DrugCentral uuid:ed51d98e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ed5202ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.016']} DrugCentral uuid:ed522b5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ed5253e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ed527c90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:ed52a774-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.131']} DrugCentral uuid:ed52d00a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:ed52f88c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ed532118-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ed534a62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.512']} DrugCentral uuid:ed537302-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.027']} DrugCentral uuid:ed539b84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.127']} DrugCentral uuid:ed53c500-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:ed53eda0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:ed541654-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:ed543ed6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:ed5468e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.037']} DrugCentral uuid:ed54948a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.795']} DrugCentral uuid:ed54bd34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.266']} DrugCentral uuid:ed54e5d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.524']} DrugCentral uuid:ed550f14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:ed553796-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:ed556144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ed5589ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.241']} DrugCentral uuid:ed55b310-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed55dbba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:ed560464-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:ed562cfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.506']} DrugCentral uuid:ed565676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ed567f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ed56a7ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.866']} DrugCentral uuid:ed56d132-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.936']} DrugCentral uuid:ed56faea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.06']} DrugCentral uuid:ed57245c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ed574d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ed57760a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:ed579eb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ed57c740-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ed57efc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed5819a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quetiapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ed58422e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:ed586ace-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.542']} DrugCentral uuid:ed589364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:ed58bc7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.079']} DrugCentral uuid:ed58e512-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:ed590da8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.459']} DrugCentral uuid:ed593648-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.445']} DrugCentral uuid:ed59605a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.465']} DrugCentral uuid:ed59890e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.575']} DrugCentral uuid:ed59b1b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.558']} DrugCentral uuid:ed59da6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:ed5a03b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.481']} DrugCentral uuid:ed5a2c2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:ed5a54ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.994']} DrugCentral uuid:ed5a7df0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.574']} DrugCentral uuid:ed5aa67c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ed5acef4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:ed5af7b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:ed5b20d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ed5b496a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:ed5b75e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:ed5b75e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:ed5bb2a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ed5bb2a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ed5bb2a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ed5c03c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ed5c03c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ed5c03c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ed5c03c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ed5c4f36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00592 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Phospholipase A2 group 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ed5c78ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04055 biolink:molecularly_interacts_with DrugCentral:2338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepacrine targets Enzyme (Phospholipase A2 group 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5cd37a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed5d9ab2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:ed5d9ab2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:ed5d9ab2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:ed5dddc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:ed5dddc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:ed5e1942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ed5e1942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ed5e1942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ed5e58da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2340 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.08']} DrugCentral uuid:ed5e815c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2340 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.397']} DrugCentral uuid:ed5ea9fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:ed5ecf18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinethazone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:ed5ef394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quingestanol acetate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:ed5f1900-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ed5f416e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:ed5f6748-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:ed5f8e8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:ed5fb2d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:ed5fd746-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:ed600018-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ed6028a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.125']} DrugCentral uuid:ed60513a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:ed6079b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ed60a43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed60ccd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.106']} DrugCentral uuid:ed60f568-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ed611e08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ed61490a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.061']} DrugCentral uuid:ed6171dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:ed61a22e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ed61a22e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ed61a22e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ed61e1b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ed620a34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63881 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:ed6232b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is blocker of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ed625b2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ed628482-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinidine is inhibitor of Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:ed62ad18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:ed62d6da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.102']} DrugCentral uuid:ed62ff5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.119']} DrugCentral uuid:ed632aea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:ed634f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ed6377f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:ed63a4f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:ed63a4f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:ed63d3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ed63fc7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:ed642526-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ed644e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:ed647710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ed649fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:2350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rabeprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:ed64c846-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.321']} DrugCentral uuid:ed64f258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:ed651aee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.408']} DrugCentral uuid:ed65438e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.926']} DrugCentral uuid:ed656c1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.205']} DrugCentral uuid:ed659514-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ed65bd8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ed65e62c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:ed660ecc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.553']} DrugCentral uuid:ed66391a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:ed6661ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:ed668a78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ed66b412-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ed66ddac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:ed670638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:ed672ec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.538']} DrugCentral uuid:ed6757aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.523']} DrugCentral uuid:ed67802c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.971']} DrugCentral uuid:ed67a8ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:ed67d180-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:ed67faa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.321']} DrugCentral uuid:ed68232e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.193']} DrugCentral uuid:ed684bf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ed68748c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:ed68a01a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:ed68cba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:ed68f42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ed691c8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ed694556-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ed696e5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.436']} DrugCentral uuid:ed6996dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:ed69c01c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.876']} DrugCentral uuid:ed69e89e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13393 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Enzyme (Phospholipase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed6a113e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14939 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Enzyme (Phospholipase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ed6a39b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.827']} DrugCentral uuid:ed6a63be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.073']} DrugCentral uuid:ed6a8c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.625']} DrugCentral uuid:ed6ab4ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:ed6ade66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:ed6b0756-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:ed6b2fe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:ed6b5878-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:ed6b8532-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.73']} DrugCentral uuid:ed6b8532-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.73']} DrugCentral uuid:ed6bb9da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:ed6be270-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.66']} DrugCentral uuid:ed6c0b24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raloxifene targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:ed6c364e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltegravir is inhibitor of Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:ed6c5ef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:2352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ed6c8784-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:2352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltegravir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ed6cb01a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:2352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ed6cd91e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ed6d01aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.678']} DrugCentral uuid:ed6d2a4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:ed6d52f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:ed6d7c20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ed6da498-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.244']} DrugCentral uuid:ed6dcd92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:ed6df628-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45352 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ed6e21d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ed6e4cf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:ed6e7576-ac81-11ec-8b6b-0242ac110002 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ed6e9e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:ed6ec7ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:2353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raltitrexed targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ed6ef082-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:2354 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramatroban targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:ed6f1922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2354 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramatroban is inverse agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:ed6f424e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:2354 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramatroban targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ed6f6ae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XKD3 biolink:molecularly_interacts_with DrugCentral:2354 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramatroban is antagonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ed6f93f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:2354 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramatroban is antagonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ed6fbc9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:2355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramelteon is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.9']} DrugCentral uuid:ed6fe622-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:2355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramelteon is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.39']} DrugCentral uuid:ed700ed6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramipril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.342']} DrugCentral uuid:ed70378a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramipril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ed706098-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2357 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:ed7089b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ranitidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.86']} DrugCentral uuid:ed70b25a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ranitidine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ed70dae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:2358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ranitidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ed71039a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ranitidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:ed712cbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:2358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ranitidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ed71557a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ranolazine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ed717e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ranolazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:ed71a67e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ranolazine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:ed71ce60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5YLN7 biolink:molecularly_interacts_with DrugCentral:2359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ranolazine targets Unclassified (Voltage-gated sodium channel Nav1.5 cardiac isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ed71f73c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2360 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rebamipide is agonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ed7220fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ed724a0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:ed7272ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:ed729b4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:ed72c4fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ed72ee26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.194']} DrugCentral uuid:ed7316bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ed733f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:ed7367de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:ed7394fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:ed7394fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:ed73ccd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.387']} DrugCentral uuid:ed73ccd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.387']} DrugCentral uuid:ed7400c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regadenoson is agonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:ed74298a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regadenoson targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.398']} DrugCentral uuid:ed74520c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regadenoson targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ed747a84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regadenoson targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ed74a338-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regadenoson targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:ed74cc82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2363 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remifentanil is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:ed74f0e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2363 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remifentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ed75196c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2363 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remifentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ed7541f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ed756d86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:ed7597ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed75c038-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:ed75e8ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:ed7611b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:ed763a54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ed7662c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ed768bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:ed76c4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed76c4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed76c4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed76c4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed76c4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed771aa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09428 biolink:molecularly_interacts_with DrugCentral:2366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 repaglinide targets Ion channel (ATP-binding cassette sub-family C member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ed77455c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:2366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 repaglinide targets Transporter (Solute carrier organic anion transporter family member 1B1) DrugCentral uuid:ed7769ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 repaglinide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ed779764-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:ed779764-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:ed77cfae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:ed77cfae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:ed7803d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2368 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reproterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:ed782846-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rescinnamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:ed784cc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:ed787616-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.415']} DrugCentral uuid:ed789ea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.232']} DrugCentral uuid:ed78c756-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ed78f032-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.737']} DrugCentral uuid:ed791ad0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:ed794352-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:ed796be8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ed79946a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q27963 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ed79bd82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ed79e618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:ed7a16a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed7a16a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed7a16a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed7a57c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BRU6 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:ed7a805a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2370 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reserpine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.836']} DrugCentral uuid:ed7aa904-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:2372 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol acetate targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ed7ad258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:2372 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol acetate targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:ed7afb66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribavirin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ed7b23e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55263 biolink:molecularly_interacts_with DrugCentral:2373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribavirin targets Kinase (Adenosine kinase) DrugCentral uuid:ed7b485a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22413 biolink:molecularly_interacts_with DrugCentral:2373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribavirin targets Enzyme (Ectonucleotide pyrophosphatase/phosphodiesterase family member 1) DrugCentral uuid:ed7b6d08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49902 biolink:molecularly_interacts_with DrugCentral:2373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribavirin targets Enzyme (Cytosolic purine 5'-nucleotidase) DrugCentral uuid:ed7b9170-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:2373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribavirin is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ed7bba92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:2373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribavirin is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ed7be31e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:2373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribavirin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:ed7c0c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:2373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribavirin is inhibitor of Enzyme (NS5B protein) DrugCentral uuid:ed7c30ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribavirin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ed7c5984-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WGY9 biolink:molecularly_interacts_with DrugCentral:2376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifabutin targets Enzyme (DNA-directed RNA polymerase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ed7c8db4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7c8db4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7c8db4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7c8db4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7cd508-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ed7cfd80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ed7d25f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:ed7d4ede-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:ed7d776a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ed7da00a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:ed7dc8b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin is inhibitor of Enzyme (DNA-directed RNA polymerase subunit beta) DrugCentral uuid:ed7deeca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:ed7e1760-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.29']} DrugCentral uuid:ed7e401e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed7e68fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:ed7e9280-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:2377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifampicin targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:ed7ec6a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7ec6a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7ec6a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7ec6a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7f08aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifaximin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:ed7f3d20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7f3d20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7f3d20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7f3d20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:ed7f7f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2381 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilmenidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:ed7fa7ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2381 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilmenidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ed7fd118-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2381 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilmenidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:ed7ff9ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2381 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilmenidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ed802258-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2381 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilmenidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:ed804ae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:2381 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilmenidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:ed807712-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riluzole is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:ed809d78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riluzole is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ed80c60e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riluzole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.765']} DrugCentral uuid:ed80efee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:2382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riluzole is activator of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ed811fd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riluzole targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:ed814444-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:2382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ed816cbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riluzole targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed8196d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:2382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:ed81c004-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riluzole is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ed81e87c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:2382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ed82120c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21430 biolink:molecularly_interacts_with DrugCentral:2383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimantadine targets Ion channel (Matrix protein 2) DrugCentral uuid:ed82387c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimantadine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:ed8260fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimantadine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:ed8289a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63231 biolink:molecularly_interacts_with DrugCentral:2383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimantadine is inhibitor of Ion channel (Matrix protein 2) DrugCentral uuid:ed82ae1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:2383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimantadine targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ed82d76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:2383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimantadine targets Unclassified (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ed830004-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05778 biolink:molecularly_interacts_with DrugCentral:2383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ed8328b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DOF8 biolink:molecularly_interacts_with DrugCentral:2383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ed835180-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimexolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed83b012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ed84894c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2387 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risedronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:ed84b2be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2387 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risedronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ed84db68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q197X6 biolink:molecularly_interacts_with DrugCentral:2387 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risedronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:ed8503f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WS26 biolink:molecularly_interacts_with DrugCentral:2387 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risedronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:ed852c80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ed8555ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levisoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:ed857e6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levisoprenaline targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ed85a700-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04274 biolink:molecularly_interacts_with DrugCentral:2388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levisoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:ed85d0a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ed85fbf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ed8624aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ed864d40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ed867770-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:ed86a01a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:ed86c8b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ed86f164-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:ed871a5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.788']} DrugCentral uuid:ed8742cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ed876bc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.443']} DrugCentral uuid:ed87945c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.364']} DrugCentral uuid:ed87bf04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ed87e7a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ed88112a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:ed8839c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:ed886314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:ed888baa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ed88b44a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:ed88dd4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.023']} DrugCentral uuid:ed8905e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:ed892e70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:ed895710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ed8980f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.432']} DrugCentral uuid:ed89aa08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ed89d28a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.538']} DrugCentral uuid:ed89fb2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:ed8a2488-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ed8a4d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:ed8a75b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.278']} DrugCentral uuid:ed8a9e40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ed8ac74e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ed8aefe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:ed8b187a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:ed8b40e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.687']} DrugCentral uuid:ed8b6b36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ed8b93cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ed8bbc58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.967']} DrugCentral uuid:ed8be4f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:ed8c0f96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:ed8c3822-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:ed8c60e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ed8c8b2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:ed8cb3e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:ed8cdc8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:ed8d052c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:ed8d2ea8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ed8d573e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ed8d7fc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:ed8da86a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ed8dd1a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ed8dfa22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:ed8e22b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ed8e4b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ed8e7542-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ed8e9dd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed8ed1d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ed8ed1d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ed8ed1d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ed8ed1d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ed8f25c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:ed8f25c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:ed8f25c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:ed8f6cea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ed8f6cea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ed8f6cea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ed8fae26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risperidone targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:ed8fd6da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritodrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:ed8fff52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritodrine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ed9027d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.575']} DrugCentral uuid:ed9050f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:ed90795a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:ed90a1e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:ed90cb08-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:ed90ef98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:ed91182e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:ed9140a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.303']} DrugCentral uuid:ed9169e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:ed919272-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.119']} DrugCentral uuid:ed91bc16-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:ed91e4a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.058']} DrugCentral uuid:ed920d9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir is inhibitor of Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ed923664-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:ed925f0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir is inhibitor of Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed9287ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:ed92b256-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ed92dc9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:ed930512-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:2391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ritonavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.47']} DrugCentral uuid:ed932dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivastigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:ed935710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivastigmine is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ed938082-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:ed93a904-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivastigmine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:ed93d172-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ed93fa4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:ed9422ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ed944b66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivastigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ed9474a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivastigmine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ed949f76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivastigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:ed94c870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ed94f0e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ed951a28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ed9542a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ed956b4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ed9593cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.854']} DrugCentral uuid:ed95bcda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ed95e584-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ed960e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ed963688-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79400 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ed966504-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed966504-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rizatriptan targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ed96a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ed96a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ed96a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ed96ec36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ed96ec36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ed96ec36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ed96ec36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ed97388a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rofecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:ed976116-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ed978a06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:2397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rofecoxib targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.466']} DrugCentral uuid:ed97b292-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:2397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rofecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ed97db1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:2397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ed9803a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:ed982cc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ed985558-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:2397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:ed987dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:ed98a652-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:2397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ed98cf7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rolitetracycline targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ed98f800-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:2399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rolitetracycline targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ed99206e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rolitetracycline targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ed9948f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43351 biolink:molecularly_interacts_with DrugCentral:2399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rolitetracycline targets Nuclear other (DNA repair protein RAD52 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ed9971e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:ed999a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:ed99c30c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:ed99eb84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:ed9a1794-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ed9a4002-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ed9a688e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ed9a91ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:ed9aba6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:ed9ae3e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:ed9b0c80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:ed9b35de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ed9b5e6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:ed9b8714-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ed9bafb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ed9bd962-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropinirole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:ed9c0220-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:ed9c2aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:ed9c4f00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:ed9c73f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:ed9c9866-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:ed9cbcce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:ed9ce140-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:ed9d076a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:ed9d2bdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:ed9d547c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:ed9d7cf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ed9da6de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.391']} DrugCentral uuid:ed9dcf42-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:ed9df7ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:ed9e2078-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:ed9e4990-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:ed9e721c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:ed9e9aa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ed9ec320-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ed9eed8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.449']} DrugCentral uuid:ed9f1604-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ed9f3e90-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ed9f66f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ed9f92aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:ed9fbd66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ed9fe5de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37238 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:eda00ec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:eda03764-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:eda05fe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:eda0885e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:eda0b216-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:eda0daa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0K020 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eda10338-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:eda12ba6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:eda15626-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:eda1809c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N5K1 biolink:molecularly_interacts_with DrugCentral:2405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:eda1a928-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosuvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:eda1d1aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosuvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:eda1fa7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43924 biolink:molecularly_interacts_with DrugCentral:2406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rosuvastatin targets Enzyme (Phosphodiesterase 6D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.9']} DrugCentral uuid:eda222fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rotigotine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eda24b94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rotigotine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:eda27416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rotigotine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:eda29d42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rotigotine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:eda2c6e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rotigotine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:eda2f09e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rotigotine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eda319b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rotigotine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:eda345b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roxatidine acetate is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eda36e98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:2410 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roxithromycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:eda392ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:2410 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roxithromycin is agonist of GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:eda3bbe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2410 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roxithromycin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.261']} DrugCentral uuid:eda3e49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2413 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rupatadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.41']} DrugCentral uuid:eda40d26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:2413 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rupatadine targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:eda435a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ademetionine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eda45ec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17708 biolink:molecularly_interacts_with DrugCentral:2414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ademetionine targets Enzyme (S-adenosylmethionine decarboxylase proenzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:eda48756-ac81-11ec-8b6b-0242ac110002 UniProtKB:C3SIU2 biolink:molecularly_interacts_with DrugCentral:2414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ademetionine targets Unclassified (Met repressor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:eda4aff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11086 biolink:molecularly_interacts_with DrugCentral:2414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ademetionine targets Enzyme (Phenylethanolamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:eda4d86e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22061 biolink:molecularly_interacts_with DrugCentral:2414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ademetionine targets Enzyme (Protein-beta-aspartate methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:eda50262-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eda52b02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:eda553c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.95']} DrugCentral uuid:eda57c38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6RYA0 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Salicylic acid-binding protein 2) DrugCentral uuid:eda5a10e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:eda5c9a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:eda5f258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:eda61af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eda6444c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eda66ce2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:eda69604-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:eda6be72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:eda6eabe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.36']} DrugCentral uuid:eda7134a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:eda73be0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salicylic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:eda764d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:eda78d84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salmeterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.41']} DrugCentral uuid:eda7b61a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salmeterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eda7deb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salmeterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:eda807c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salmeterol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.004']} DrugCentral uuid:eda83054-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salmeterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eda858b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salmeterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:eda8814e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:eda8aad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:eda8d496-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.408']} DrugCentral uuid:eda8fd18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:eda92590-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:eda94e80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:eda9773e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.282']} DrugCentral uuid:eda99fd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.699']} DrugCentral uuid:eda9c86a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.555']} DrugCentral uuid:eda9f1aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.556']} DrugCentral uuid:edaa1a36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:edaa3e8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.003']} DrugCentral uuid:edaa672a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.153']} DrugCentral uuid:edaa92a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.187']} DrugCentral uuid:edaabb3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.661']} DrugCentral uuid:edaae3bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.684']} DrugCentral uuid:edab0db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:edab3650-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:edab5edc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:edab8754-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:edabb09e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:edabd916-ac81-11ec-8b6b-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:edac01b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:2422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saquinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:edac2a4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:edac5436-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:edac7cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:edacadbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:edacadbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:edacadbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:edaced4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:edad15c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.86']} DrugCentral uuid:edad3e3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:edad66c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:edad8fea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:edadb88a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:edade0f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:edae0984-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:edae34f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:edae6064-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:edae99da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:edae99da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:edae99da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:edae99da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:edae99da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:edaef268-ac81-11ec-8b6b-0242ac110002 UniProtKB:C3TDZ2 biolink:molecularly_interacts_with DrugCentral:2427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 secnidazole targets Enzyme (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:edaf1af4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:2428 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 secobarbital targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.578']} DrugCentral uuid:edaf4b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:edaf4b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:edaf4b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:edaf8426-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selegiline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.171']} DrugCentral uuid:edafacc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selegiline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.764']} DrugCentral uuid:edafd57a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selegiline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:edaffeba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:edb02750-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:edb04ff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:edb07890-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:2429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:edb0a18a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:edb0ce1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selegiline targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:edb0ce1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selegiline targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:edb101e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 seratrodast targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:edb12b3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:2433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sermorelin is agonist of GPCR (Growth hormone-releasing hormone receptor) DrugCentral uuid:edb14fb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:edb17416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertaconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:edb19ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:edb1c682-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:edb1f15c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:edb21a06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.194']} DrugCentral uuid:edb243e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:edb26cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:edb295c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:edb2be66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:edb2e6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:edb31032-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:edb338be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:edb3614a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:edb389e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:edb3b5be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:edb3dfbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:edb40870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:edb43156-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:edb459ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:edb482aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:edb4ab4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:edb4d4b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:edb4fd20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:edb525ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:edb54e56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:edb577aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:edb5a036-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:edb5c8e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:edb5f16c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:edb62236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:edb62236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:edb62236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:edb66a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:edb66a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:edb66a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:edb6aa44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:edb6d2c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:edb6fb7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2435 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertindole is inverse agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:edb723fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.965']} DrugCentral uuid:edb74de6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:edb77690-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:edb79f3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.54']} DrugCentral uuid:edb7c7c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:edb7f0ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.106']} DrugCentral uuid:edb81960-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.666']} DrugCentral uuid:edb84200-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.246']} DrugCentral uuid:edb86a8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:edb893d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.082']} DrugCentral uuid:edb8bcd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:edb8e566-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:edb90dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:edb93944-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.854']} DrugCentral uuid:edb961c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:edb98b9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.187']} DrugCentral uuid:edb9b482-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:edb9de12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:edba066c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.475']} DrugCentral uuid:edba2f16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.365']} DrugCentral uuid:edba584c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.885']} DrugCentral uuid:edba810a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:edbaa996-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:edbad236-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:edbafc0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sertraline targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:edbb2498-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 setastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:edbb48f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive modulator of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:edbb6d86-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:edbb9248-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:edbbb6ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:edbbdb2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:edbbffbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbc5e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:edbd1f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.526']} DrugCentral uuid:edbd4854-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:edbd714e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sibutramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.962']} DrugCentral uuid:edbd99c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sibutramine targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:edbdbf6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.026']} DrugCentral uuid:edbde804-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:2440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sibutramine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:edbe1162-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sibutramine is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:edbe39ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sibutramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.538']} DrugCentral uuid:edbe6270-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62897 biolink:molecularly_interacts_with DrugCentral:2440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sibutramine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:edbe8b06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:edbeb478-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:edbedd18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:edbf0644-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Transporter (Multidrug resistance-associated protein 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:edbf2f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:edbf57b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) DrugCentral uuid:edbf7c32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:edbfa4c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:edbfcdd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:edbff64e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:edc01ee4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13946 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:edc0477a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51160 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:edc07178-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76083 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:edc09c0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60658 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:edc0c57e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.094']} DrugCentral uuid:edc0ee32-ac81-11ec-8b6b-0242ac110002 UniProtKB:O54735 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:edc11736-ac81-11ec-8b6b-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:edc13fcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:edc16830-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16586 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:edc190c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11541 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:edc1b9f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:edc1e27e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O77746 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:edc20ee8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:edc20ee8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:edc24f48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:edc24f48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:edc24f48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:edc24f48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:edc2a524-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:edc2a524-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:edc2a524-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:edc2a524-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:edc2f79a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:edc2f79a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:edc2f79a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:edc33bba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:edc33bba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:edc383c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:edc383c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:edc383c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:edc383c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:edc383c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:edc383c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:edc3ed3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:edc3ed3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:edc3ed3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:edc42fde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:edc45a72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14099 biolink:molecularly_interacts_with DrugCentral:2441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:edc482ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:edc4abb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:edc4d448-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:edc4fce8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:edc5257e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:edc54ec8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:edc57768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.73']} DrugCentral uuid:edc59ff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:edc5c92a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:edc5f36e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:edc61de4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:edc6467a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:edc66f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:edc69846-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:edc6c0dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:edc6e972-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:edc7121c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:edc73c4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21447 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Transporter (P-glycoprotein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:edc7650a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:edc78daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14142 biolink:molecularly_interacts_with DrugCentral:2443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silymarin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:edc7b640-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2445 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:edc7dd50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2445 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:edc8071c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2445 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simvastatin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:edc82fda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2445 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:edc858d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2445 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simvastatin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:edc88156-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q10283 biolink:molecularly_interacts_with DrugCentral:2445 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:edc8a9f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.431']} DrugCentral uuid:edc8d296-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:edc8fbb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:edc92444-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:edc94ce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:edc97548-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:edc99f14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00688 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:edc9c7be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:edc9f022-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:edca18a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13451 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:edca41bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q53EL6 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Nuclear other (Programmed cell death protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:edca6a2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06730 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Nuclear other (Eukaryotic translation initiation factor 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:edca92c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26883 biolink:molecularly_interacts_with DrugCentral:2446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:edcabb42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:2447 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sisomicin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:edcae054-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14740 biolink:molecularly_interacts_with DrugCentral:2448 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:edcb08d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2448 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitagliptin targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:edcb32e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2448 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.774']} DrugCentral uuid:edcb5b74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28843 biolink:molecularly_interacts_with DrugCentral:2448 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:edcb8694-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:2448 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:edcbaf3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:2448 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:edcbd7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:2448 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:edcc00c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHL4 biolink:molecularly_interacts_with DrugCentral:2448 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:edcc2964-ac81-11ec-8b6b-0242ac110002 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:2448 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:edcc51be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:2449 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitafloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:edcc7626-ac81-11ec-8b6b-0242ac110002 UniProtKB:P72525 biolink:molecularly_interacts_with DrugCentral:2449 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitafloxacin targets Enzyme (DNA topoisomerase 4 subunit A) DrugCentral uuid:edcc9b06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:edccc3ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:edccec50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:edcd14e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:edcd3e80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:edcd670c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:edcd8f8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:edcdb824-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06746 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (DNA polymerase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:edcde0f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:edce0ab8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:edce334e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:edce5be4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:edce8538-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:2452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sivelestat targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:edceadb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24158 biolink:molecularly_interacts_with DrugCentral:2452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sivelestat targets Enzyme (Myeloblastin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:edced63c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3UP87 biolink:molecularly_interacts_with DrugCentral:2452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sivelestat targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:edcefed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:edcf2a88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:edcf565c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.88']} DrugCentral uuid:edcf7ede-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:edcfa7c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:edcfd05a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:edcff8e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:edd0219a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:edd04aee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:edd07406-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:edd09ca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:edd0c546-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:edd0ef4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:edd117e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:edd14084-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:edd1692e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:edd19246-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:edd1bae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:edd1e39a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:edd20c44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:edd23584-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:edd25e24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:edd286b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:edd2af28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:edd2da70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:edd302fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:edd32bb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:edd355a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:edd37e58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:edd3a702-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:edd3cfca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.68']} DrugCentral uuid:edd3fa22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:edd422d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:edd44b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:edd473da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:edd49e82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:edd4ca2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:edd4f4f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:edd51d8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:edd54670-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:edd56f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:edd597a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:edd5c032-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:edd5e95e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:edd611d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:edd63a62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:edd6649c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:edd69016-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:edd6b8de-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:edd6e16a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:edd70a50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:edd732d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:edd75c80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:edd7850c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:edd7ae4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:edd7d6ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:edd7ff96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:edd82822-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:edd853d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:edd87c78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:edd8a504-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53778 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:edd8cd86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:edd8f68a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:edd91eee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:edd94766-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:edd9709c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:edd99932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:edd9c1c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:edd9ea68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:edda15c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:edda3e50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:edda66f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:edda8f86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:eddab876-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:eddae116-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eddb0998-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:eddb3238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:eddb5c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:eddb851c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:eddbad94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:eddbd620-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:eddc01f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:eddc2af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:eddc5352-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:eddc7c6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:eddca4ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:eddccd8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:eddcf78a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15264 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:eddd20ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:eddd4938-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:eddd71b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:eddd9a50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:edddc3cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:edddec44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:edde14d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:edde3d52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:edde6642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:edde8eec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:eddeb782-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:eddee004-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:eddf093a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:eddf31a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:eddf5b2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eddf8392-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:eddfad22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49336 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:eddfd5ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:eddffe4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ede02874-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ede05114-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00526 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ede079aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:ede0a24a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ede0cb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:ede0f42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ede11cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:ede1452e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ede16fea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ede19b8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVW4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase-like 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:ede1c422-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ede1ec9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ede21580-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ede23e0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:ede2668e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:ede28f24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:ede2b85a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ede2e104-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:ede30990-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ede332f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:ede35c9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ede38528-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:ede3adaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ede3d69a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ede3ffb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5GIT4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ede42848-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ede450b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8T9Z7 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ede479f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ede4a26e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05622 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:ede4cb0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:ede4f3a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ede51d52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ede545e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ede56e88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ede5971e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:2459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:ede5c018-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:2463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ede5e8a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09250 biolink:molecularly_interacts_with DrugCentral:2463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ede61130-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XZT6 biolink:molecularly_interacts_with DrugCentral:2463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorivudine targets Kinase (Deoxynucleoside kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ede63ae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00142 biolink:molecularly_interacts_with DrugCentral:2463 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sorivudine targets Kinase (Thymidine kinase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:ede66432-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2464 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sotalol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ede68ce6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2464 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sotalol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ede6b590-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2464 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sotalol is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:ede6df48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2464 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sotalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:ede70acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:2464 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sotalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ede733ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sparfloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.413']} DrugCentral uuid:ede76184-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sparfloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:ede76184-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sparfloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:ede79442-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sparfloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ede79442-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sparfloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ede7c2aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:2468 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spectinomycin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:ede7e708-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2469 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiclomazine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:ede80f94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:ede838de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:ede86192-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:ede889f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ede8b3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:ede8dea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ede9076e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:ede92ffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ede9598a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ede98216-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ede9aad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:ede9d374-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ede9fcaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.322']} DrugCentral uuid:edea2540-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:edea4de0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:edea766c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:edeaa0a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:edeac950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:edeaf1dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:edeb1a7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.297']} DrugCentral uuid:edeb4380-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:edeb6d24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:edeb95b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:edebbefa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:edebe79a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:edec1166-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:edec39fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:edec633c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:edec8be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:edecb486-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:edecdd1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.87']} DrugCentral uuid:eded0634-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:eded2ed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:eded66b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eded66b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eded66b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eded66b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eded66b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ededc920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ededc920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ededc920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ededc920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:edee2334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:edee2334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:edee2334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:edee2334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:edee2334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:edee8450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:edee8450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:edee8450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:edeecbb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:edeecbb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:edeecbb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:edef1a6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:edef1a6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:edef1a6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:edef1a6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:edef1a6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:edef709a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02665 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets Unclassified (Beta-casein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:edef993a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:edefc1d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spiperone targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:edefea70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2474 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spirapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:edf013ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:2474 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spirapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:edf03d68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spironolactone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.227']} DrugCentral uuid:edf06680-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spironolactone targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:edf08ae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spironolactone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.884']} DrugCentral uuid:edf0b3e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spironolactone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:edf0dc96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spironolactone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.029']} DrugCentral uuid:edf10518-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spironolactone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:edf12dae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spironolactone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:edf156e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spironolactone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:edf17f7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spironolactone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.663']} DrugCentral uuid:edf1a914-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2475 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spironolactone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:edf1d1a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.033']} DrugCentral uuid:edf1fcf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stanozolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.327']} DrugCentral uuid:edf2259c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stanozolol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:edf24e3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stanozolol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:edf272f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.948']} DrugCentral uuid:edf29b76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:edf2c3ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stanozolol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:edf2ec7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stanozolol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.316']} DrugCentral uuid:edf315ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:2478 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stavudine targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:edf33a4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2478 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stavudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:edf362c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2478 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stavudine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:edf38b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2480 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stiripentol targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:edf3b0c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:2480 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stiripentol targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:edf3dc34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2480 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stiripentol targets Enzyme (Cytochrome P450 1A2) DrugCentral uuid:edf4007e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2480 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stiripentol targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:edf424e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WH62 biolink:molecularly_interacts_with DrugCentral:2481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 streptomycin targets Ribosomal protein (30S ribosomal protein S12) DrugCentral uuid:edf449c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:edf47252-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:edf49ae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:edf4c36a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:edf4eca0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:edf51cde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:edf51cde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:edf51cde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:edf55c1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07727 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:edf58700-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYW0 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine targets GPCR (Taste receptor type 2 member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:edf5b2b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:2484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 strychnine is agonist of GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.367']} DrugCentral uuid:edf5dd7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:2487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 succinic acid targets Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:edf60748-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BXA5 biolink:molecularly_interacts_with DrugCentral:2487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 succinic acid is agonist of GPCR (Succinate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:edf6301a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suxamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:edf668d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:edf668d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:edf668d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:edf668d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:edf668d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:edf6b4b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:edf6dde4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:edf7065c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:edf72f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:edf758b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:edf78410-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:edf7b82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:edf7b82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:edf7b82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:edf7b82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:edf8030e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:edf82b86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2491 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sufentanil targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:edf853fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:edf87c80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:edf8a5b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:edf8ceb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:edf8f82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:edf920b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13661 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase OXA-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:edf94c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:edf9752c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:edf99dc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:edf9c6a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:edf9ef2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:edfa17b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:edfa4042-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7X575 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:edfa696e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0VTR6 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:edfa91f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0VTR8 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:edfaba5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:D5HSX5 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:edfae2fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P83111 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Serine beta-lactamase-like protein LACTB, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:edfb0c5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62594 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:edfb360a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0VTS0 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (ADC-18 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:edfb5ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00809 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:edfb8736-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:edfbb012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:2492 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:edfbd920-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.819']} DrugCentral uuid:edfc01c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.155']} DrugCentral uuid:edfc2a56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:edfc538c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:edfc7c18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:edfca4c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.716']} DrugCentral uuid:edfccd6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:edfcf6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.786']} DrugCentral uuid:edfd20b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.977']} DrugCentral uuid:edfd495e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.053']} DrugCentral uuid:edfd7262-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.142']} DrugCentral uuid:edfd9b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.258']} DrugCentral uuid:edfdc3ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.727']} DrugCentral uuid:edfdec56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.144']} DrugCentral uuid:edfe15a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:edfe3e2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:edfe66cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:edfe8f76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:edfeb528-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:edfedda0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:edff0636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:edff2ecc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:edff57d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:edff805c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.431']} DrugCentral uuid:edffa8de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.738']} DrugCentral uuid:edffd174-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:edfffab4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:ee002336-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.782']} DrugCentral uuid:ee004bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ee007426-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ee009eec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:2495 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee00c75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfacetamide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:ee00effa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfacetamide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee011458-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:2497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfacetamide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:ee013fdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q25704 biolink:molecularly_interacts_with DrugCentral:2499 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfacytine is inhibitor of Kinase (7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase; Dihydropteroate synthetase) DrugCentral uuid:ee01644e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2500 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadiazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ee018cbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2500 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadiazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ee01b5fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08210 biolink:molecularly_interacts_with DrugCentral:2500 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadiazine targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) DrugCentral uuid:ee01da78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2500 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadiazine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee01fecc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2500 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadiazine targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:ee022758-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZV3 biolink:molecularly_interacts_with DrugCentral:2500 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadiazine targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ee02507a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2501 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadimethoxine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.206']} DrugCentral uuid:ee027b22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2502 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadimidine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee029f94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2502 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadimidine targets Enzyme (Lactoylglutathione lyase) DrugCentral uuid:ee02c424-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q25704 biolink:molecularly_interacts_with DrugCentral:2503 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadoxine is inhibitor of Kinase (7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase; Dihydropteroate synthetase) DrugCentral uuid:ee02e8a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IAU3 biolink:molecularly_interacts_with DrugCentral:2503 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadoxine targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:ee0311ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:2504 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfaethidole targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:ee033a3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfaguanidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:ee036a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:ee036a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:ee036a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:ee03aac4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2510 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfamerazine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee03cf36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfameter is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee03f3bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2512 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfamethizole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee04181a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08192 biolink:molecularly_interacts_with DrugCentral:2514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfamethoxazole targets Enzyme (Bifunctional protein FolC) DrugCentral uuid:ee043dae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfamethoxazole is inhibitor of Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ee046630-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfamethoxazole targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ee048eb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfamethoxazole targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ee04b748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfamethoxazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ee04e042-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2517 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfalene is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee0504b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ee052d40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ee0556d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ee057fde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ee05a87e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:ee05d11e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee05f586-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:ee06209c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ee064932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ee0671b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ee069ab8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ee06c506-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ee06edc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ee07166e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:ee073f9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ee07683a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ee0790f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ee07b998-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:ee07e3fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:ee080c86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:ee083530-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ee085dd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ee0886de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ee08af6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ee08d800-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ee090104-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:ee092a6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:ee09530c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:ee097cb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ee09a65e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee09cf12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00921 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:ee09f794-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ee0a2048-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ee0a494c-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfanilamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ee0a71ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfaphenazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:ee0a9a8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfaphenazole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee0abf26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfapyridine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee0ae442-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q49184 biolink:molecularly_interacts_with DrugCentral:2524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfapyridine targets Enzyme (Dihydropteroate synthase type-1) DrugCentral uuid:ee0b08c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:ee0b3168-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ee0b59f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24752 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Enzyme (Acetyl-CoA acetyltransferase, mitochondrial) DrugCentral uuid:ee0b7fb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:ee0ba6ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Transporter (Cystine/glutamate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:ee0bcfb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ee0bf8be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.707']} DrugCentral uuid:ee0c219a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.628']} DrugCentral uuid:ee0c4a30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.533']} DrugCentral uuid:ee0c72c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine is inhibitor of Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:ee0c9c6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.768']} DrugCentral uuid:ee0cc582-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.198']} DrugCentral uuid:ee0cf20a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:ee0cf20a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:ee0d2072-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:ee0d491c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfasalazine targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:ee0d72c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfathiazole is inhibitor of Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ee0d9c78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:2527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfathiazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.161']} DrugCentral uuid:ee0dc50e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfathiazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:ee0dee26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25084 biolink:molecularly_interacts_with DrugCentral:2527 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfathiazole targets Unclassified (Transcriptional activator protein LasR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ee0e16a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfinpyrazone targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:ee0e3afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfinpyrazone targets GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ee0e63a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:2528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfinpyrazone is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ee0e8cd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2528 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfinpyrazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ee0eb568-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfafurazole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ee0edde0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08210 biolink:molecularly_interacts_with DrugCentral:2529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfafurazole targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) DrugCentral uuid:ee0f0234-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfafurazole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:ee0f27dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:2529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfafurazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:ee0f50c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:2529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfafurazole targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:ee0f7962-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfafurazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:ee0fa1da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60760 biolink:molecularly_interacts_with DrugCentral:2531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfobromophthalein targets Enzyme (Hematopoietic prostaglandin D synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:ee0fca98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulforidazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.611']} DrugCentral uuid:ee0ff338-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2532 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulforidazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:ee101bf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C0X1 biolink:molecularly_interacts_with DrugCentral:2533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aldesulfone is inhibitor of Enzyme (Dihydropteroate synthase 1) DrugCentral uuid:ee104036-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aldesulfone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:ee106552-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:ee108dca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ee10b688-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ee10df14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:ee1108f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:ee113162-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Enzyme (72 kDa type IV collagenase) DrugCentral uuid:ee1155d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:ee117e92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.362']} DrugCentral uuid:ee11a76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ee11d0e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ee11fa02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:ee122270-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:ee124cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulindac targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:ee12755e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:ee129e12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.307']} DrugCentral uuid:ee12c6bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:ee12f34e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.857']} DrugCentral uuid:ee131ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.508']} DrugCentral uuid:ee134740-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:ee13703a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.146']} DrugCentral uuid:ee1398f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.606']} DrugCentral uuid:ee13c198-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.053']} DrugCentral uuid:ee13ea56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.965']} DrugCentral uuid:ee141378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.009']} DrugCentral uuid:ee143c2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.196']} DrugCentral uuid:ee1464c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:ee148d76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.426']} DrugCentral uuid:ee14b8a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ee14e488-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:ee150d50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:ee1535e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ee155ed6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.141']} DrugCentral uuid:ee158762-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.645']} DrugCentral uuid:ee15afda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:ee15da14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:ee1602d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.121']} DrugCentral uuid:ee162b90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ee165430-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ee167e10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:ee16a91c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ee16d1da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:ee16fa70-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:ee172392-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:ee174c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:ee1774f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:ee179d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:ee17c6f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:ee17effc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ee18189c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ee18425e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GJU1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ee186fa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:ee18983a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:ee18c0f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ee18ea10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:ee1912a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ee193b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:ee1963e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:ee198d1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ee19b5bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ee19de52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ee1a07d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:ee1a4112-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ee1a4112-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ee1a4112-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ee1a4112-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ee1a4112-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ee1a96f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:ee1abffc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ee1ae8b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2537 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulpiride targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:ee1b113c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:2538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ee1b39d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:ee1b62f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:2538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:ee1b8ba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:2538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ee1bb452-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:2538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ee1bdce8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:2538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:ee1c077c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:2538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.38']} DrugCentral uuid:ee1c3238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:2538 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ee1c5ad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ee1c836e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:ee1cac90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:ee1cd53a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:ee1cfde4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ee1d2684-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:ee1d5488-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ee1d7d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:ee1da5aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:ee1dd0e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:ee1dfae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ee1e239a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ee1e4c58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:ee1e7566-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:ee1e9e10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ee1ec6b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2540 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultiame targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ee1eef3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2541 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.571']} DrugCentral uuid:ee1f1886-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2541 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sultopride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:ee1f413a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:ee1f69f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ee1f92a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:ee1fbd36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ee1fe5ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:ee200ebc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ee203784-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:ee2060a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:ee208932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ee20b1d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:ee20db44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ee2103e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ee212c98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ee215538-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ee217eb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79400 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ee21a754-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:ee21d0da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:ee21f97a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ee22229c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ee224b32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N2B7 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:ee2273d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8MI13 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan targets Unclassified (5-hydroxytryptamine 1D receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:ee229c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:2543 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ee22c5bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ee22ee66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ee231706-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:ee233fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.12']} DrugCentral uuid:ee236ba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:ee239488-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:ee23bdaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:ee23e6ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ee241066-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:ee24391a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ee2461ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ee248b0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.66']} DrugCentral uuid:ee24b3c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ee24dc80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ee25053e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ee252f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:ee2557b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:ee258054-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ee25a8b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ee25d2ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ee25fb42-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:ee2623d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ee264c78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:ee2675b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:ee269e58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:ee26c6e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ee26f024-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ee2718d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:ee27415a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ee276a04-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ee2792f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:ee27bb8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:ee27e40c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ee280cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ee283614-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:ee285eaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:ee288736-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:ee28afe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ee28d90c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:ee2901b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ee292a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:ee2952d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ee297bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ee29a468-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:ee29ce0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ee29f7d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ee2a21ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ee2a4a4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ee2a72d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ee2a9c7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ee2ac53c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:ee2aede6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ee2b1672-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ee2b3f6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ee2b67ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ee2b908e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ee2bb924-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:ee2be246-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ee2c0ac8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ee2c3368-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:ee2c5bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:ee2c85de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ee2cae60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:ee2cd714-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ee2cff8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:ee2d2886-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:ee2d5108-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ee2d7976-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ee2da20c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ee2dcc64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.26']} DrugCentral uuid:ee2df504-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ee2e1d90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ee2e4720-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:ee2e6ff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ee2e9888-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2H1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 38-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ee2ec114-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:ee2ee9f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ee2f1286-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ee2f3b1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:ee2f63bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ee2f8cfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ee2fb588-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:ee2fde14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:ee3007e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ee30324c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:ee305b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ee308396-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ee30ac2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ee30d530-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ee30fe52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:ee3126d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:ee314fec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:ee31788c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ee31a136-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ee31ca9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ee31f488-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:ee321d78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ee324618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ee326e9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:ee329794-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JI10 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ee32c02a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ee32e8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:ee33114c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ee333a78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ee3362e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:ee338b90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:ee33b41c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ee33de6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:ee340700-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:ee342f96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ee34582c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ee348176-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ee34aa02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:ee34d27a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ee34fb92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ee352432-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ee354caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ee357536-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ee359f02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ee35c8a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:ee35f11e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ee361ad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ee3643ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ee366c8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:ee36951a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ee36bdc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:ee36e6b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ee370f4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ee3737cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:ee376076-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ee378cf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:ee37b602-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N752 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Casein kinase I isoform alpha-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:ee37de84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ee380792-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78368 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ee38301e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ee3858c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:ee38815e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:ee38aa62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ee38d2f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ee38fb84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ee39242e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ee394df0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ee39767c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:ee399f08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:ee39c88e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ee39f19c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:ee3a1a32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:ee3a42be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ee3a6b2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:ee3a943a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ee3abcd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ee3ae55c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ee3b0dfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ee3b3a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:ee3b64d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ee3b8d68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ee3bb68a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ee3bdf20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:ee3c07b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:ee3c318c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ee3c5a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ee3c833a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:ee3cabd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ee3cd45c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ee3cff9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ee3d286c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ee3d50f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:ee3d798e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ee3da29c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ee3dcc22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ee3df4b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:ee3e1d58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:ee3e46de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDC3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase BRSK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:ee3e6f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ee3e97f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ee3ec208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ee3eeaee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:ee3f1398-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ee3f3c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:ee3f6514-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16566 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ee3f8daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11799 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ee3fb654-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ee3fdee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ee4007f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ee403084-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:ee40592e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:ee4081ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCP0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ee40abae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ee40d426-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:ee40fcbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ee412552-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ee414e60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ee417700-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ee419f8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IWQ3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase BRSK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ee41c912-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ee41f20c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:ee421a98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ee42443c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:ee426e08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ee4296a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:ee42bf3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:ee42e7ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ee431114-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:ee4339b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:ee43625e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ee438af4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:ee43b3d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:ee43dc70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ee4404fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ee442d88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:ee445772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ee448012-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ee44a8b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ee44d148-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80370 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Unclassified (Protein delta homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:ee44fb1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ee4523be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ee454c40-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:ee457530-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ee459dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:ee45c738-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ee45efce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ee4619ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:ee4644b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:ee466d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ee4695aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ee46bf08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:ee46e7b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ee47103e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:ee4738de-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:ee4761e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:ee478a8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ee47b322-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ee47dbae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15208 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:ee4806ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:ee482f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ee485926-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43172 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Nuclear other (U4/U6 small nuclear ribonucleoprotein Prp4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ee488266-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:ee48ab06-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.23']} DrugCentral uuid:ee48d39c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ee48fc3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:ee49255e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ee494e08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:ee49769e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ee49a02e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:ee49c9be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:ee49f25e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:ee4a1af4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:ee4a4376-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ee4a6c8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ee4a9510-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ee4abdba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ee4ae66e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ee4b0fc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.05']} DrugCentral uuid:ee4b384e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:ee4b60e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ee4b8984-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ee4bb4ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:ee4bdd44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:ee4c05e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ee4c2f6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRH2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (SNF-related serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ee4c580a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:ee4c80a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ee4ca936-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:ee4cd262-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ee4cfb02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ee4d23a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:ee4d4c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H8M2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Unclassified (Bromodomain-containing protein 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ee4d76ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ee4da28c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.509']} DrugCentral uuid:ee4dcb36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ee4df408-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.229']} DrugCentral uuid:ee4e1d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:2544 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sunitinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.959']} DrugCentral uuid:ee4e45b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:ee4e6f96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ee4e982c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2546 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suprofen targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.347']} DrugCentral uuid:ee4ec1a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47872 biolink:molecularly_interacts_with DrugCentral:2548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 secretin human is agonist of GPCR (Secretin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ee4eea2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ee4f12d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ee4f3c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:ee4f66e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:ee4f8f84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:ee4fb82e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04844 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Ion channel (Acetylcholine receptor subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ee4fe114-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:ee500996-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ee503218-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:ee505aa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ee5083c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:ee50ac5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ee50d4de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:ee50fd42-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ee512844-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ee5152b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32738 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Choline O-acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:ee517b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ee51a4cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ee51cdd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ee51f670-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ee521f7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01984 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Histamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ee5248be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ee527154-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ee5299cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.61']} DrugCentral uuid:ee52c64a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:ee52c64a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:ee52ffac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:ee52ffac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:ee5342f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:ee5342f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:ee5342f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:ee5342f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:ee5342f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:ee5398fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.91']} DrugCentral uuid:ee53c194-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2551 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrine is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:ee53eba6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ee541432-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ee543d54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:ee5465e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:ee548e6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.398']} DrugCentral uuid:ee54b7d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P60568 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Cytokine (Interleukin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.72']} DrugCentral uuid:ee54e0ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48454 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:ee550a36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:ee5532b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ee555c20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ee5584a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13451 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ee55ad56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15393 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Nuclear other (Splicing factor 3B subunit 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ee55d5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96AY3 biolink:molecularly_interacts_with DrugCentral:2552 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:ee55ff04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ee56279a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ee565030-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:ee5678b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:ee56a2ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O54735 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ee56cb8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:ee56f40e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11541 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ee57305e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ee57305e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ee57305e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ee57305e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ee57305e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ee57305e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ee57a476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ee57a476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ee57a476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ee57a476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ee57a476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ee57a476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:ee5806c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tadalafil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5869ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee5924f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2557 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talinolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ee594d80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2557 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talinolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ee5975ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2557 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talinolol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:ee599b14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2557 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talinolol targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ee59c396-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2557 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talinolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ee59ec2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2557 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talinolol targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ee5a1490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:ee5a3dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.915']} DrugCentral uuid:ee5a663e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ee5a8eac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:ee5ab71a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:ee5ae0dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:ee5b0968-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:ee5b31ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ee5b5a6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ee5b8370-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:ee5babe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:ee5bdc12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ee5bdc12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ee5bdc12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ee5c1d62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:2560 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 taltirelin is agonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ee5c462a-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.807']} DrugCentral uuid:ee5c6ea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.001']} DrugCentral uuid:ee5c972e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:ee5cc028-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.357']} DrugCentral uuid:ee5ce896-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:ee5d112c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.372']} DrugCentral uuid:ee5d3af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.335']} DrugCentral uuid:ee5d6442-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ee5d8cb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.139']} DrugCentral uuid:ee5db53c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ee5dde54-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ee5e06d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:ee5e2f62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ee5e5802-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.907']} DrugCentral uuid:ee5e811a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:ee5eaaaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.158']} DrugCentral uuid:ee5ed32c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:ee5efbc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:ee5f24e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.618']} DrugCentral uuid:ee5f4d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:ee5f769c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.794']} DrugCentral uuid:ee5f9f3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:ee5fca0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.034']} DrugCentral uuid:ee5ff2a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.167']} DrugCentral uuid:ee601b2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.557']} DrugCentral uuid:ee6043ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:ee606c96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:ee609522-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.731']} DrugCentral uuid:ee60bd90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:ee60e612-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.238']} DrugCentral uuid:ee610f3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.835']} DrugCentral uuid:ee6137ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.858']} DrugCentral uuid:ee616042-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:ee6189c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:ee61b498-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.407']} DrugCentral uuid:ee61dd2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.611']} DrugCentral uuid:ee62059c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.204']} DrugCentral uuid:ee622ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:ee62574a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ee627fcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.328']} DrugCentral uuid:ee62a934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:ee62d26a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:ee62faba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Nuclear hormone receptor (Estrogen-related receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ee63235a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.449']} DrugCentral uuid:ee634cea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.069']} DrugCentral uuid:ee63777e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.095']} DrugCentral uuid:ee639ff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.923']} DrugCentral uuid:ee63c878-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:ee63f0f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.038']} DrugCentral uuid:ee6419d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ee644258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.913']} DrugCentral uuid:ee646ae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.821']} DrugCentral uuid:ee649366-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.919']} DrugCentral uuid:ee64bc9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.533']} DrugCentral uuid:ee64e51e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.604']} DrugCentral uuid:ee650daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.761']} DrugCentral uuid:ee653744-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.419']} DrugCentral uuid:ee656066-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.515']} DrugCentral uuid:ee6588d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.587']} DrugCentral uuid:ee65b156-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:ee65da14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:ee66028c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ee662b04-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.061']} DrugCentral uuid:ee66537c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BY08 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Enzyme (Emopamil-binding protein-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:ee66809a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBM7 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Enzyme (Anti-estrogen binding site (AEBS)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ee66809a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBM7 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Enzyme (Anti-estrogen binding site (AEBS)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:ee66b61e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2561 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamoxifen targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ee66de8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:ee6707d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.87']} DrugCentral uuid:ee67306c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ee6758e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:ee678184-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.54']} DrugCentral uuid:ee67aa74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:ee67d2ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ee67fb6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.24']} DrugCentral uuid:ee6823fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:ee684d12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:ee6875a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:ee689e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:ee68c6a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:ee68f168-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ee6925ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ee6925ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ee6925ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ee6925ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ee697188-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tandospirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:ee699a8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tandospirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:ee69c322-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2563 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tandospirone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:ee69ebea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:2571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ee6a153e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:2571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ee6a3ed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2571 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ee6a6746-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ee6a8faa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.527']} DrugCentral uuid:ee6ab9e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.602']} DrugCentral uuid:ee6ae342-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:ee6b0bc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59401 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ee6b343c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:ee6b5d0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10424 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.524']} DrugCentral uuid:ee6b857c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q46991 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (IMI-1; IMI-1 carbapenemase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ee6badf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ee6bd658-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6W9J1 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ee6bff66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:ee6c27c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P94958 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ee6c5038-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05193 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:ee6c789c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A4KCT8 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ee6ca2cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ee6ccb30-ac81-11ec-8b6b-0242ac110002 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ee6cf3b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ee6d1c20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9F663 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Carbepenem-hydrolyzing beta-lactamase KPC) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:ee6d4524-ac81-11ec-8b6b-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:ee6d6d6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ee6d95ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD64 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ee6dbf0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6GWS8 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ee6de786-ac81-11ec-8b6b-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ee6e0ffe-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0ZX81 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ee6e3876-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:ee6e6350-ac81-11ec-8b6b-0242ac110002 UniProtKB:B8R6A5 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ee6e8f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2XPY6 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:ee6eb7d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ee6ee046-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ee6f0a44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q670S6 biolink:molecularly_interacts_with DrugCentral:2572 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ee6f32d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ee6f5b8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 1A) DrugCentral uuid:ee6f7ff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tegaserod is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ee6fa918-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 1D) DrugCentral uuid:ee6fcd94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tegaserod targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ee6ff63e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:2579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tegaserod is partial agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ee701efc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:2580 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teicoplanin aglycone is inhibitor of Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:ee704a58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2581 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ee707320-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telmisartan targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ee709b98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telmisartan targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:ee70c49c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:2583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telmisartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.31']} DrugCentral uuid:ee70ed82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telmisartan targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ee7115fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:2583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telmisartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:ee713e68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telmisartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:ee71679e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telmisartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:ee719020-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2583 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telmisartan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:ee71b88e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 temazepam targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:ee71e4bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ee71e4bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ee71e4bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ee721ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2586 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 temocapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.444']} DrugCentral uuid:ee724830-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2586 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 temocapril is inhibitor of Enzyme (Angiotensin-converting enzyme) DrugCentral uuid:ee726c8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2590 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teniposide targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:ee7290f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:2590 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teniposide is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:ee72b5ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2590 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teniposide targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:ee72d9f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:2590 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teniposide targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:ee72fe38-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:2590 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teniposide targets Transporter (Canalicular multispecific organic anion transporter 2) DrugCentral uuid:ee7322a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenofovir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ee734bd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:2592 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenofovir targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:ee73741c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:2593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenofovir disoproxil targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:ee7398a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2593 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenofovir disoproxil is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:ee73bce2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2595 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenoxicam targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:ee73e2b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2595 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenoxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.943']} DrugCentral uuid:ee740e5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terbinafine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.67']} DrugCentral uuid:ee743776-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terbinafine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.628']} DrugCentral uuid:ee746002-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terbinafine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.388']} DrugCentral uuid:ee7489f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terbinafine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:ee74b282-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:2597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terbinafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ee74db22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:2597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terbinafine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:ee74ffa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terbinafine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.662']} DrugCentral uuid:ee7528fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52020 biolink:molecularly_interacts_with DrugCentral:2597 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terbinafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:ee755188-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2598 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terbutaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ee757a1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2598 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terbutaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ee75a2aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.373']} DrugCentral uuid:ee75ce74-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:ee75f94e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.895']} DrugCentral uuid:ee7621e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.433']} DrugCentral uuid:ee764afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:ee767518-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.216']} DrugCentral uuid:ee769da4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.599']} DrugCentral uuid:ee76c63a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.632']} DrugCentral uuid:ee76ef5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.438']} DrugCentral uuid:ee7717f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:ee77407e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:ee77691e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.862']} DrugCentral uuid:ee7793d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.338']} DrugCentral uuid:ee77be64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.511']} DrugCentral uuid:ee77e6dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.718']} DrugCentral uuid:ee780f7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.504']} DrugCentral uuid:ee783862-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:ee78610c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.362']} DrugCentral uuid:ee78897a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ee78b224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:ee78d736-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.666']} DrugCentral uuid:ee78ffcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.963']} DrugCentral uuid:ee792862-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ee7950e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ee797d08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.612']} DrugCentral uuid:ee79a8aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.102']} DrugCentral uuid:ee79d366-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.389']} DrugCentral uuid:ee79fc60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:ee7a24e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:ee7a4d64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:2599 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terconazole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ee7a76b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.874']} DrugCentral uuid:ee7aa110-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.687']} DrugCentral uuid:ee7ac9ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:ee7af21e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:ee7b1aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.719']} DrugCentral uuid:ee7b461a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:ee7b7126-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:ee7b99da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ee7bc252-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:ee7beb74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:ee7c1400-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:ee7c3d22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ee7c664e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:ee7c8eee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.693']} DrugCentral uuid:ee7cb770-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.448']} DrugCentral uuid:ee7cdfde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:ee7d09f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.213']} DrugCentral uuid:ee7d339e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51589 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets Enzyme (Cytochrome P450 2J2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ee7d5c2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:ee7d84c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ee7dad88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.734']} DrugCentral uuid:ee7dd614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:ee7dfea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:ee7e2ed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:ee7e2ed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:ee7e2ed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:ee7e6fb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2600 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terfenadine targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:ee7e9824-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:ee7ec0b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ee7eebb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:ee7f1614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ee7f3ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:ee7f675e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:ee7f906c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ee7fb916-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:ee7fe1ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ee800a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ee80336e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:ee805d26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ee8085bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ee80afc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:ee80daa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ee810334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:ee812bc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:ee8154ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ee817d50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ee81a5e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:ee81ce7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ee81f7b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terguride is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:ee822052-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2603 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terodiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ee82499c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tertatolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.087']} DrugCentral uuid:ee827246-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:ee829d16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tertatolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ee82c5a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:2605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ee82ee38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ee83173c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:2606 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testolactone is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:ee83402c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:ee8368cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:ee839158-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:ee83ba7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ee83e2de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ee840b88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:ee843414-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ee845d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:ee848658-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.599']} DrugCentral uuid:ee84aeee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:ee84db58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ee84db58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ee850fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35627 biolink:molecularly_interacts_with DrugCentral:2607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone targets Nuclear hormone receptor (Constitutive androstane receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:ee85380a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2608 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone undecanoate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:ee855c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetrabenazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:ee8584cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetrabenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:ee85adee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetrabenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:ee85d684-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetrabenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ee85ff06-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q27963 biolink:molecularly_interacts_with DrugCentral:2609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetrabenazine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ee862986-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:2609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetrabenazine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:ee865686-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:2609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetrabenazine is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ee868aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ee868aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ee868aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ee86cea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ee86f712-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.153']} DrugCentral uuid:ee871fa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.011']} DrugCentral uuid:ee87483e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.766']} DrugCentral uuid:ee8771a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ee879a0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine targets Ion channel (Sodium channel protein type 8 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ee87c2aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ee87eb0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.499']} DrugCentral uuid:ee8815f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00194 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine targets Ion channel (cGMP-gated cation channel alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ee884644-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ee884644-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ee884644-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ee888d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ee888d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ee888d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ee88cccc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:2611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:ee88f120-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:2611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:ee891574-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29475 biolink:molecularly_interacts_with DrugCentral:2612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sapropterin targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.95']} DrugCentral uuid:ee893f0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00439 biolink:molecularly_interacts_with DrugCentral:2612 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sapropterin is activator of Enzyme (Phenylalanine-4-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ee896876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2615 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:ee8990f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2615 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:ee89b998-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2615 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:ee89e364-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:2615 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:ee8a0bfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:ee8a3468-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.432']} DrugCentral uuid:ee8a5cc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:2616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thalidomide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ee8a85a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:ee8aae20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:2616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ee8ad6ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:2616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:ee8aff42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:2616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.393']} DrugCentral uuid:ee8b2878-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ee8b50fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.85']} DrugCentral uuid:ee8b799a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ee8ba35c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ee8bcfda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:ee8bfb9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:ee8c244e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:ee8c4d20-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:ee8c7598-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:ee8c9e10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ee8cc692-ac81-11ec-8b6b-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:ee8cef96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ee8d1822-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ee8d409a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:ee8d6dfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ee8d6dfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:ee8da634-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ee8ddaa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ee8ddaa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ee8ddaa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ee8ddaa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ee8e2d02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:ee8e2d02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:ee8e2d02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:ee8e6bc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ee8e9436-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60614 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:ee8ebd58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS9 biolink:molecularly_interacts_with DrugCentral:2620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 theophylline targets Unclassified (Transmembrane domain-containing protein TMIGD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:ee8ee666-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.22']} DrugCentral uuid:ee8f0ef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:ee8f374c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09508 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole targets Enzyme (Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial) DrugCentral uuid:ee8f5d4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:ee8f8814-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:ee8fb096-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AE18 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:ee8fd918-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ee9009b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:ee9009b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:ee9009b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:ee9058ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:ee9058ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:ee9058ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:ee9058ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:ee9058ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:ee9058ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:ee9058ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:ee90bb9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:2624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamphenicol targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:ee90e006-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamphenicol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ee910892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:2624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamphenicol targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee916b7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:ee9224de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:ee924d74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:ee9276c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:ee929f54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:ee92c7cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ee92f058-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ee931c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ee9344ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:ee936e3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:ee939738-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:ee93bfc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:ee93e418-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:ee940876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:ee942cca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:ee9452f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:ee94775c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:ee94a010-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiethylperazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ee94c860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.221']} DrugCentral uuid:ee94f484-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.912']} DrugCentral uuid:ee952008-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:ee95470e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:ee956e28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) DrugCentral uuid:ee959286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:ee95bb12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) DrugCentral uuid:ee95df70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00492 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) DrugCentral uuid:ee9604e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.258']} DrugCentral uuid:ee962d7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.792']} DrugCentral uuid:ee9655fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26281 biolink:molecularly_interacts_with DrugCentral:2632 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioguanine targets Kinase (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.75']} DrugCentral uuid:ee968678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ee968678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ee968678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee96f90a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:ee97cbd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63734 biolink:molecularly_interacts_with DrugCentral:2633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiopental is gating inhibitor of Ion channel (Potassium voltage-gated channel subfamily C member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:ee97f508-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2635 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioproperazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.347']} DrugCentral uuid:ee981d8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2635 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioproperazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:ee984616-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:ee986a74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ee989742-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ee98c2ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.872']} DrugCentral uuid:ee98ebc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:ee9914b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ee993d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ee9965be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.813']} DrugCentral uuid:ee998e5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ee99b780-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ee99dfda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:ee9a09a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ee9a3246-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ee9a5cf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ee9a87b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ee9ab04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.466']} DrugCentral uuid:ee9ad8d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ee9b01bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ee9b2a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ee9b52d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.866']} DrugCentral uuid:ee9b7b60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ee9ba4a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.569']} DrugCentral uuid:ee9bcd22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:ee9bf5ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.595']} DrugCentral uuid:ee9c1e30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:ee9c4a90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:ee9c74de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:ee9c9d56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:ee9cc63c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:ee9ceed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.126']} DrugCentral uuid:ee9d1754-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.774']} DrugCentral uuid:ee9d3fe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.751']} DrugCentral uuid:ee9d690c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:ee9d91a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.686']} DrugCentral uuid:ee9dba06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:ee9de2b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:ee9e0f38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:ee9e3b02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:ee9e66ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.712']} DrugCentral uuid:ee9e93e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.531']} DrugCentral uuid:ee9ebc58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.195']} DrugCentral uuid:ee9ee4e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.297']} DrugCentral uuid:ee9f0d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:ee9f367e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:ee9f5f14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.284']} DrugCentral uuid:ee9f87be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:ee9fb02c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:ee9fdab6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:eea0069e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:eea03272-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:eea05bb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:eea084b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:eea0bc9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eea0bc9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eea0bc9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eea0bc9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eea0bc9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eea11ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:eea11ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:eea11ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:eea11ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:eea171d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:eea171d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:eea171d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:eea1c286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:eea1c286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:eea1c286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:eea1c286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:eea1c286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:eea21ff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:eea21ff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:eea21ff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:eea26768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:eea26768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:eea26768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:eea2a69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:2637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioridazine is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:eea2d04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2638 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiotepa is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:eea2f99e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.292']} DrugCentral uuid:eea3225c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.347']} DrugCentral uuid:eea34afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:eea3746e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:eea39e80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:eea3c702-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eea3ef8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:eea4186a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.681']} DrugCentral uuid:eea440e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.817']} DrugCentral uuid:eea46a72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.94']} DrugCentral uuid:eea49308-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eea4bc3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.412']} DrugCentral uuid:eea4e4ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.583']} DrugCentral uuid:eea50d60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:eea535f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.386']} DrugCentral uuid:eea55fcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.585']} DrugCentral uuid:eea5884e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:eea5b0da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:eea5d9de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:eea602c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.318']} DrugCentral uuid:eea62b3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:eea653c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.181']} DrugCentral uuid:eea67c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:eea6a54e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.693']} DrugCentral uuid:eea6cde4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:eea6f684-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:eea72050-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.442']} DrugCentral uuid:eea74c10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:2646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor alpha) DrugCentral uuid:eea77212-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:2646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:eea79a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levothyroxine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:eea7c366-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levothyroxine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:eea7ebf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:2646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levothyroxine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:eea8146a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:2646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levothyroxine targets Unclassified (THAP domain-containing protein 1) DrugCentral uuid:eea838dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:2646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levothyroxine targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:eea862e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40926 biolink:molecularly_interacts_with DrugCentral:2646 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levothyroxine targets Enzyme (Malate dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:eea88b8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:2648 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiagabine is inhibitor of Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:eea8b564-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23978 biolink:molecularly_interacts_with DrugCentral:2648 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:eea8de0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31648 biolink:molecularly_interacts_with DrugCentral:2648 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:eea9091a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31651 biolink:molecularly_interacts_with DrugCentral:2648 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent betaine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:eea93cd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:eea93cd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:eea93cd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:eea983d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:eea983d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:eea983d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:eea9c382-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2650 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tianeptine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:eea9ec18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2651 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.077']} DrugCentral uuid:eeaa14a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2651 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.108']} DrugCentral uuid:eeaa3dee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2651 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.756']} DrugCentral uuid:eeaa6684-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2651 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiapride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:eeaa8f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiaprofenic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:eeaab79c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiaprofenic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:eeaae302-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tibolone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.317']} DrugCentral uuid:eeab0ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tibolone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:eeab3726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tibolone targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:eeab5b98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tibolone targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:eeab8050-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tibolone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:eeaba8c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:2655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tibolone targets Enzyme (Steryl-sulfatase) DrugCentral uuid:eeabcd3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tibolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.123']} DrugCentral uuid:eeabf5e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tibolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.542']} DrugCentral uuid:eeac200a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2656 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticarcillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:eeac5c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eeac5c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eeac5c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eeac5c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eeac5c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eeac5c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eeac5c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:eeacbf42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:eeaceae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:eead15dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:eead3ed6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.747']} DrugCentral uuid:eead6758-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.857']} DrugCentral uuid:eead8fee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.767']} DrugCentral uuid:eeadb9a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.201']} DrugCentral uuid:eeade2e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eeae0b7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:eeae33fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine is antagonist of GPCR (P2Y purinoceptor 12) DrugCentral uuid:eeae585c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.175']} DrugCentral uuid:eeae823c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eeaeaac8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:eeaed368-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2657 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticlopidine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:eeaefbd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tienilic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.494']} DrugCentral uuid:eeaf24bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tilidine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:eeaf4d3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:2664 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiliquinol targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:eeaf75ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2666 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiludronic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) DrugCentral uuid:eeaf9a28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13488 biolink:molecularly_interacts_with DrugCentral:2666 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiludronic acid targets Enzyme (V-type proton ATPase 116 kDa subunit a isoform 3) DrugCentral uuid:eeafc5ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2666 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiludronic acid targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:eeafef50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50281 biolink:molecularly_interacts_with DrugCentral:2666 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiludronic acid targets Enzyme (Matrix metalloproteinase-14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:eeb017f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:2666 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiludronic acid targets Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:eeb04072-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2672 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tinoridine is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.987']} DrugCentral uuid:eeb06afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O69638 biolink:molecularly_interacts_with DrugCentral:2673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiocarlide targets Enzyme (Epoxide hydrolase EphE; Hydrolase, alpha/beta hydrolase fold family) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:eeb0937e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2675 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tioconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:eeb0b7e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:2675 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tioconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eeb0e0d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2676 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiopronin targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:eeb1094e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:eeb131da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:eeb15a70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiotropium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11.1']} DrugCentral uuid:eeb183b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:eeb1ac46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:eeb1d4d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:eeb1fd68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:eeb226bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2677 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:eeb24f48-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1PT23 biolink:molecularly_interacts_with DrugCentral:2678 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eeb2784c-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1PWR7 biolink:molecularly_interacts_with DrugCentral:2678 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.94']} DrugCentral uuid:eeb2a0f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:F1PGZ2 biolink:molecularly_interacts_with DrugCentral:2678 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:eeb2c9d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2679 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiracizine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:eeb2f650-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:2680 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirofiban is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:eeb2f650-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:2680 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirofiban is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:eeb32a26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tizanidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:eeb35366-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tizanidine is agonist of GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:eeb37904-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tizanidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:eeb3a190-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tizanidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:eeb3cb48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tizanidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:eeb3f532-ac81-11ec-8b6b-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:2683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tizanidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:eeb41fe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:2684 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tobramycin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.824']} DrugCentral uuid:eeb46b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eeb46b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eeb46b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eeb46b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eeb46b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eeb46b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eeb46b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eeb46b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eeb46b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eeb46b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:eeb4f18a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2693 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofisopam targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:eeb51a7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2693 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofisopam targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:eeb543b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2694 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazamide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.292']} DrugCentral uuid:eeb57038-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2694 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) DrugCentral uuid:eeb57038-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2694 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) DrugCentral uuid:eeb59ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:eeb5c894-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:eeb5f3a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:eeb61c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:eeb644fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:eeb675aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:eeb675aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:eeb675aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:eeb6bc86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:eeb6bc86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:eeb6bc86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:eeb6fdb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:2696 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolbutamide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:eeb7263a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:2696 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolbutamide is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:eeb752cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2696 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:eeb752cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2696 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:eeb786ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2697 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolcapone targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.69']} DrugCentral uuid:eeb7b186-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:2697 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolcapone targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:eeb7db34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:2697 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolcapone targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:eeb803b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13118 biolink:molecularly_interacts_with DrugCentral:2697 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolcapone targets Nuclear other (Krueppel-like factor 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:eeb82cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2697 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolcapone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:eeb855d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:2697 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolcapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.569']} DrugCentral uuid:eeb87e54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2698 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolfenamic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eeb8a6ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2698 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolfenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:eeb8cff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2698 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolfenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:eeb8f87a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2698 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolfenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:eeb92110-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:2698 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolfenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:eeb949ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2699 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolmetin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:eeb973b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2699 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolmetin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:eeb99f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2699 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolmetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:eeb9cae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2699 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolmetin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:eeb9f57c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:2699 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolmetin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:eeba1e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2699 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolmetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.667']} DrugCentral uuid:eeba46e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:2701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolonium targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:eeba6f66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:2701 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolonium targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:eeba97de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:eebac236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:eebaeacc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:2702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:eebb136c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:eebb3c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toloxatone is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:eebb67cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolperisone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.253']} DrugCentral uuid:eebb908a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolperisone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:eebbb92a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70634 biolink:molecularly_interacts_with DrugCentral:2703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolperisone targets Unclassified (SMR1-alpha3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:eebbe242-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70635 biolink:molecularly_interacts_with DrugCentral:2703 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolperisone targets Unclassified (BetaB2-crystallin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.474']} DrugCentral uuid:eebc0ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:2704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:eebc3350-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:2704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:eebc5bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80276 biolink:molecularly_interacts_with DrugCentral:2704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:eebc84ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eebcad6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:2704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:eebcd5f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:2704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eebcfe70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q91WR5 biolink:molecularly_interacts_with DrugCentral:2704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolrestat targets Enzyme (Aldo-keto reductase family 1 member C21) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:eebd2954-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:2704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolrestat targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:eebd521c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolrestat is inhibitor of Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.509']} DrugCentral uuid:eebd7a9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:eebda316-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:eebdcc42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.57']} DrugCentral uuid:eebdf62c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:eebe1ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:eebe47f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:eebe712e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:eebe99ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:eebec368-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:eebeed0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:eebf18fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:2705 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:eebf42b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:eebf6746-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:eebf8c12-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:eebfb08e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:eebfd942-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:eec00200-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:eec02b4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:eec053e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:eec07c80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eec0a50c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:eec0cea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:eec0f750-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:eec11ffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:eec148a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:eec1719e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:eec19a2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:eec1c2e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:eec1eb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27139 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:eec214a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:eec23d40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.63']} DrugCentral uuid:eec265c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:eec28e58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:eec2b860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:eec2e1e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:eec30aae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:eec333bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:eec35c5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:eec38592-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:eec3ae32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:eec3d894-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:eec4013e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:eec429e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:eec452b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:eec4847e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:eec4847e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:eec4847e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:eec4c09c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eec4c09c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:eec5044e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:eec5044e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:eec5044e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:eec5044e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:eec5044e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:eec55c1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:eec55c1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:eec55c1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:eec55c1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:eec59e5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:eec5c78a-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiramate targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:eec5f020-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.818']} DrugCentral uuid:eec61898-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:eec63ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:eec6638e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:eec687f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:eec6ac40-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:eec6d0b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan is inhibitor of Enzyme (DNA topoisomerase I, mitochondrial) DrugCentral uuid:eec6f56a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.58']} DrugCentral uuid:eec71e00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:eec74678-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:eec76ef0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:eec7981c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:eec7c0b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04750 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Enzyme (DNA topoisomerase I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:eec7e916-ac81-11ec-8b6b-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:eec811fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WIQ1 biolink:molecularly_interacts_with DrugCentral:2707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topotecan targets Enzyme (UDP-galactopyranose mutase) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:eec83d6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2708 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 torsemide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:eec8665c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toremifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:eec88ede-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toremifene is modulator of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:eec8b4e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:2709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toremifene targets Nuclear hormone receptor (Estrogen-related receptor gamma) DrugCentral uuid:eec8d948-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05320 biolink:molecularly_interacts_with DrugCentral:2709 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toremifene targets Unclassified (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:eec901e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramadol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:eec92b1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramadol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:eec95436-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramadol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:eec97cc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramadol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:eec9a544-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramadol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:eec9cdda-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:eec9f83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2711 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramadol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:eeca23c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2712 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trandolapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:eeca4cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranexamic acid is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eeca7672-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60760 biolink:molecularly_interacts_with DrugCentral:2714 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranilast targets Enzyme (Hematopoietic prostaglandin D synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:eeca9f80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.229']} DrugCentral uuid:eecac80c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.225']} DrugCentral uuid:eecaf0ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:eecb1956-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:eecb42d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:eecb6b5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:eecb944e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eecbbe74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:eecbe750-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.88']} DrugCentral uuid:eecc0fdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:eecc389a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:eecc6180-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:eecc8a16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:eeccb2d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:eeccdb74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NB78 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Enzyme (Lysine-specific histone demethylase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:eecd04d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:2715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tranylcypromine targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eecd2d68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 travoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:eecd5612-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:2716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 travoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:eecd7ea8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.428']} DrugCentral uuid:eecdaa5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:eecdd376-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:eecdfc16-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.033']} DrugCentral uuid:eece24b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:eece4dce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:eece775e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:eecea116-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:eececac4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:eecef364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:eecf1bfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:eecf4486-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.749']} DrugCentral uuid:eecf6e5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.551']} DrugCentral uuid:eecf99b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:eecfc406-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.896']} DrugCentral uuid:eecfec7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:eed01564-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.483']} DrugCentral uuid:eed03ddc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:eed06668-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:eed08efe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:eed0b834-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.153']} DrugCentral uuid:eed0e0b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:eed1094c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:eed131f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.081']} DrugCentral uuid:eed15b7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.083']} DrugCentral uuid:eed18430-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:eed1ac8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:eed1d55c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:eed1fdd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eed2267e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2717 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trazodone targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eed24f14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:2720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eed2794e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:eed2a1ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:2720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 treprostinil is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:eed2ca66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:2720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:eed2f2fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:2720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eed31d36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:2720 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 treprostinil is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:eed3491e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.642']} DrugCentral uuid:eed37506-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:eed39dec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eed3c6be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Enzyme (11-cis retinol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:eed3ef54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35398 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eed417ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:eed4408a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:eed469d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:eed493a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eed4bcb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eed4e63e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:eed50ede-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92753 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin is antagonist of Nuclear hormone receptor (Nuclear receptor ROR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.82']} DrugCentral uuid:eed5374c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:eed55fd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:eed588b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40220 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:eed5b12c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:eed5d9ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:eed60244-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62965 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:eed62b98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22935 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eed6551e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11416 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:eed67daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:eed6a636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22605 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:eed6cf9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18911 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:eed6f83e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:eed720de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:eed74956-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49116 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin is agonist of Nuclear other (Nuclear receptor subfamily 2 group C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:eed77264-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13526 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin targets Unclassified (Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:eed79af0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:2722 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretinoin is agonist of Nuclear other (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:eed7c372-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.27']} DrugCentral uuid:eed7ebfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:eed8155c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:eed83dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:eed86656-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.76']} DrugCentral uuid:eed89838-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:eed89838-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:eed89838-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:eed8eba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eed8eba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eed8eba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eed8eba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eed8eba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eed954d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:eed954d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:eed954d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:eed954d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:eed954d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:eed954d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:eed9c01e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:eed9c01e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:eed9c01e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:eeda0010-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamcinolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:eeda28a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamcinolone targets Cytosolic other (Annexin A1) DrugCentral uuid:eeda4d04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2725 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamcinolone targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:eeda7298-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamcinolone acetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:eeda9b1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamcinolone acetonide targets Cytosolic other (Annexin A1) DrugCentral uuid:eedabf82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2726 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamcinolone acetonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:eedae82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2727 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamcinolone diacetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:eedb0cee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamterene targets Transporter (Solute carrier family 12 member 1) DrugCentral uuid:eedb31d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamterene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:eedb5a6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamterene targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.436']} DrugCentral uuid:eedb82f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08311 biolink:molecularly_interacts_with DrugCentral:2728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamterene targets Enzyme (Cathepsin G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:eedbac1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamterene targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:eedbdc8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eedbdc8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eedbdc8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eedc1bd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:eedc460e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.879']} DrugCentral uuid:eedc70b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:eedca112-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:eedca112-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:eedca112-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:eedce9d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:eedce9d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:eedce9d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:eedd30d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:eedd30d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:eedd30d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:eedd78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:eedd78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:eedd78b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:eeddbf98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:eeddbf98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:eeddbf98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:eede07c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:eede07c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:eede07c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eede872a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eedf895e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eee046c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:eee046c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:eee046c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:eee08f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:eee08f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:eee08f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:eee0d7be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:eee0d7be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:eee0d7be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:eee11f76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:eee11f76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:eee11f76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:eee16698-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:eee16698-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:eee16698-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:eee1a5cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:eee1d150-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7']} DrugCentral uuid:eee1fcde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:eee225d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:eee24e78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:eee2775e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:eee2a076-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:eee2c916-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:eee2f256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:eee31ae2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:eee34382-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:eee36cf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:eee39724-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclabendazole targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee3f926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:eee4b3d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2737 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tridihexethyl is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:eee4d8fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2737 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tridihexethyl is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:eee4fd6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:eee525f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:eee54ea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:eee579ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:eee5a488-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:eee5cd14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:eee5f5c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.31']} DrugCentral uuid:eee61eb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:eee64762-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:eee670e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:eee69a28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eee6c2be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:eee6eb68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2738 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trientine targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:eee71408-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.841']} DrugCentral uuid:eee73e1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:eee769b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:eee7952c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:eee7bdea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:eee7e702-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:eee80fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.022']} DrugCentral uuid:eee83838-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:eee860e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:eee88a36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.849']} DrugCentral uuid:eee8b2c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.536']} DrugCentral uuid:eee8db6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:eee903ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.786']} DrugCentral uuid:eee92e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.251']} DrugCentral uuid:eee956b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:eee97f5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:eee9a84e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.407']} DrugCentral uuid:eee9d0d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:eeea0118-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:eeea0118-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:eeea0118-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:eeea4308-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:eeea6b94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.27']} DrugCentral uuid:eeea9434-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:eeeabcca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:eeeae6aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:eeeb124c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06760 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Enzyme (Beta-glucuronidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:eeeb3dee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00697 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Enzyme (Lysozyme C-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:eeeb66ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eeeb8fe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:eeebb864-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BY08 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Enzyme (Emopamil-binding protein-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:eeebe8ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:eeebe8ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:eeebe8ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:eeec3082-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eeec3082-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eeec3082-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:eeec774a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:eeec774a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:eeec774a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:eeecb7c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2740 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:eeece090-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:eeed0930-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:eeed31e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluperidol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:eeed5ae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.456']} DrugCentral uuid:eeed8374-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:eeedad18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:eeedd61c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluperidol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:eeedff66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2742 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triflupromazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:eeee2806-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2742 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triflupromazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:eeee50a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2742 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triflupromazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:eeee7932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2742 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triflupromazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:eeeea4de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2742 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triflupromazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:eeeecda6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2742 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triflupromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:eeeef628-ac81-11ec-8b6b-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:2743 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluridine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:eeef1eaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:2743 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifluridine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.01']} DrugCentral uuid:eeef483a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trihexyphenidyl targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:eeef721a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trihexyphenidyl is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:eeef9ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.73']} DrugCentral uuid:eeefc418-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:eeefeca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:eef01530-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.99']} DrugCentral uuid:eef03dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2745 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trihexyphenidyl targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.611']} DrugCentral uuid:eef06800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26439 biolink:molecularly_interacts_with DrugCentral:2746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilostane is inhibitor of Enzyme (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2) DrugCentral uuid:eef08f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alimemazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:eef0b6de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alimemazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:eef0e280-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:2750 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetazidine targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:eef10cec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2751 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethadione is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:eef13154-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:2752 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetaphan targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:eef155a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2752 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetaphan targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) DrugCentral uuid:eef17a10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2752 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetaphan targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eef1a35a-ac81-11ec-8b6b-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:2752 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetaphan targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:eef1d0d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2752 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetaphan is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:eef1d0d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2752 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetaphan is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:eef1ff44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:eef227e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:eef252dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:eef27b86-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:eef2a412-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q27713 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:eef2cd0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:eef2f5ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eef31e38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:eef346f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:eef3702c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:eef398c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07807 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:eef3c13a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:eef3e9d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:eef412fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O30463 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:eef43b92-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:eef464be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:eef48d68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:eef4b676-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q27783 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:eef4df2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04174 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:eef507ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59487 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:eef53164-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q81R22 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:eef55ac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q27552 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:eef58344-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00382 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:eef5acac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:eef5d556-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q54801 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:eef601ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UUP5 biolink:molecularly_interacts_with DrugCentral:2755 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:eef62c54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:eef654e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:eef679ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:eef6a26a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:eef6cb1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:eef6f3be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:eef71cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:eef74558-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:eef76de4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07807 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:eef79684-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:eef7c0fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O30463 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:eef7e986-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:eef81226-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimetrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:eef83ada-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.827']} DrugCentral uuid:eef863f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:eef88c9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimipramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:eef8b55a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.423']} DrugCentral uuid:eef8ddfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trimipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:eef90744-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trioxsalen targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.133']} DrugCentral uuid:eef92fe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trioxsalen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.909']} DrugCentral uuid:eef95898-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2759 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trioxsalen targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:eef9819c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triparanol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:eef9aba4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triparanol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:eef9d444-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2761 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triparanol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:eef9fd7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2762 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tripelennamine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:eefa267e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triprolidine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:eefa4f00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2763 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triprolidine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.9']} DrugCentral uuid:eefa7778-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.208']} DrugCentral uuid:eefaa022-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.078']} DrugCentral uuid:eefac962-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.531']} DrugCentral uuid:eefaf202-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.013']} DrugCentral uuid:eefb1ba6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:eefb443c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:eefb6ee4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:eefb9784-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:eefbc024-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Aldose reductase) DrugCentral uuid:eefbe496-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:eefc0d86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:eefc35fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54840 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Glycogen [starch] synthase, liver) DrugCentral uuid:eefc5a5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.528']} DrugCentral uuid:eefc82e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.691']} DrugCentral uuid:eefcac3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.907']} DrugCentral uuid:eefcd4be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:eefcfd4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:eefd25ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:eefd4f5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19224 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (UDP-glucuronosyltransferase 1-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:eefd7810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:eefda088-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:eefdca90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P39654 biolink:molecularly_interacts_with DrugCentral:2767 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troglitazone targets Enzyme (Polyunsaturated fatty acid lipoxygenase ALOX15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:eefdf31c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2769 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 troleandomycin is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:eefe1ba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:eefe4434-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:eefe6d88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropicamide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:eefe9614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:eefebebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:eefee75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropicamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eeff1116-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2774 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropicamide targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:eeff39ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:eeff6256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:eeff8ae2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:eeffb3dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.606']} DrugCentral uuid:eeffdd08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ef0005b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ef002e3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ef005788-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ef008000-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:ef00a8aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ef00d14a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ef00fbe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ef01247e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49582 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:ef014d32-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70212 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:ef017a3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:ef017a3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:ef01b2fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:ef01b2fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:ef01f264-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:ef01f264-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:ef01f264-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:ef01f264-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:ef0241a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:ef0241a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:ef02757c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ef029e1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ef02ca04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:2775 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tropisetron is antagonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ef02f5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trospium targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:ef031ce8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trospium is antagonist of GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:ef034164-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trospium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:ef03661c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2776 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trospium targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:ef038a84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2777 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trovafloxacin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.306']} DrugCentral uuid:ef03b32e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2777 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trovafloxacin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.395']} DrugCentral uuid:ef03dfb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2777 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trovafloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:ef03dfb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2777 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trovafloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:ef0412b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2777 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trovafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ef0412b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2777 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trovafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:ef044122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:2780 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tryptophan is allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ef04699a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2780 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tryptophan targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:ef049316-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6DWJ6 biolink:molecularly_interacts_with DrugCentral:2780 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tryptophan is agonist of GPCR (Probable G-protein coupled receptor 139) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:ef04bbac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2780 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tryptophan targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:ef04e424-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:ef050cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:ef0536ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ef055f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ef0587da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2S1 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef05b070-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:ef05d9c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ef0602c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q401N2 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Zinc-activated ligand-gated ion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ef062c8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ef06564c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:ef067f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:ef06a7fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:ef06d086-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ef06f96c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:ef072608-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:ef072608-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:ef0761c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:ef0761c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:ef0761c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:ef07a588-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:ef07a588-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:ef07dd32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:ef07dd32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:ef0814fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef0814fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef08500a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:ef08500a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:ef0890ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ef0890ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ef0890ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ef0890ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ef08df70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ef08df70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ef091350-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef097638-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef0a4d92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:2781 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ef0a7614-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tulobuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ef0a9f18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2782 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tulobuterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:ef0ac376-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:ef0aebee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['2.7']} DrugCentral uuid:ef0b1484-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ef0b3d9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ef0b6600-ac81-11ec-8b6b-0242ac110002 UniProtKB:H9TVJ1 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (TyR1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0bc064-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef0c8558-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:2784 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:ef0cae02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2786 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tyrosine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:ef0cd67a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ef0cfede-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15144 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ef0d2904-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28838 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ef0d5212-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ef0d7a9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15145 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ef0da334-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96935 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (M1 family aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ef0dcc88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VCT3 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Aminopeptidase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ef0df500-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97629 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Leucyl-cystinyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ef0e1ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O09175 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Aminopeptidase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:ef0e47a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00727 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ef0e7020-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97449 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ef0e98ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01693 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Bacterial leucyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ef0ec174-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ef0eeaa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15684 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:ef0f132c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55786 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Puromycin-sensitive aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:ef0f3bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ef0f6462-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZ08 biolink:molecularly_interacts_with DrugCentral:2787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubenimex targets Enzyme (Endoplasmic reticulum aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ef0f8dc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 urapidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:ef0fb656-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 urapidil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:ef0fdf14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 urapidil is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:ef1007aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 urapidil is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:ef103090-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:2797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ursodiol targets Enzyme (Aldo-keto reductase family 1 member C2) DrugCentral uuid:ef1054f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ursodiol is agonist of Nuclear hormone receptor (Bile acid receptor) DrugCentral uuid:ef10794c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ursodiol targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:ef10a19c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:2797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ursodiol targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ef10cae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ursodiol targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:ef10f372-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2798 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valaciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:ef1117ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ef114156-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:ef116cb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.537']} DrugCentral uuid:ef11982c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:ef11c3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.37']} DrugCentral uuid:ef11eef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:ef121798-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:ef12402e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:ef12689c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:ef1291f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:ef12ba7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:ef12e308-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:ef130c3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:ef1336b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:ef135f5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ef1387e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ef13b062-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ef13d970-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:ef140210-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ef142be6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:ef14549a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ef147dda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:ef14a68e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:ef14cf10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:ef14f7ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:ef1523f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:ef154f94-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef157820-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ef15a0fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:ef15c988-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:ef15f21e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ef161ab4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ef16441c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:ef166ca8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O78749 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Cytochrome c oxidase subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:ef16950c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:ef16bd8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:ef16e8ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valdecoxib targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:ef1714a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valethamate targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ef173f3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:ef1767b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:ef1790ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:ef17b946-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:ef17e1e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:ef180b1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2800 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valethamate targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ef1833b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valganciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:ef185892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51649 biolink:molecularly_interacts_with DrugCentral:2803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valproic acid is inhibitor of Enzyme (Succinate-semialdehyde dehydrogenase, mitochondrial) DrugCentral uuid:ef187ce6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:2803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valproic acid targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:ef18a66c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:2803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valproic acid is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ef18cf70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:2803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ef18f7e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:2803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:ef192060-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valproic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:ef19490a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:2803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valproic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef19725e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:2803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ef199ad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35504 biolink:molecularly_interacts_with DrugCentral:2803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valproic acid targets Enzyme (UDP-glucuronosyltransferase 1-5) DrugCentral uuid:ef19bf3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5RJP0 biolink:molecularly_interacts_with DrugCentral:2803 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valproic acid targets Enzyme (Aldose reductase-related protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:ef19e838-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:2805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valrubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:ef1a0cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:2806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valsartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ef1a3676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valsartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:ef1a5ef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valsartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:ef1a8dc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valsartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:ef1a8dc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valsartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:ef1ac35c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vancomycin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ef1aebe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06241 biolink:molecularly_interacts_with DrugCentral:2807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vancomycin targets Enzyme (D-alanyl-D-alanine dipeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:ef1b1500-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17443 biolink:molecularly_interacts_with DrugCentral:2807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vancomycin targets Enzyme (UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ef1b3d8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:ef1b6604-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:ef1b926e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:ef1b926e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:ef1bcaf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:ef1bcaf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:ef1c02bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:ef1c02bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:ef1c3a98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:ef1c3a98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:ef1c7530-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ef1c7530-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ef1cad20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:ef1cad20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:ef1ce61e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:ef1ce61e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:ef1d1e5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ef1d1e5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ef1d5dec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ef1d5dec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ef1d5dec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ef1d5dec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ef1dacb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ef1dacb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ef1dec1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:ef1dec1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:ef1dec1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:ef1dec1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:ef1e38c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:ef1e6304-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.465']} DrugCentral uuid:ef1e8cb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ef1eb53e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.041']} DrugCentral uuid:ef1edef6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:ef1f0782-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ef1f3004-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76083 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:ef1f5cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ef1f5cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ef1f9d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ef1f9d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ef1f9d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ef1f9d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:ef1feb52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ef1feb52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ef2023b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin is agonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.59']} DrugCentral uuid:ef204fac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin is agonist of GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:ef2078d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin is agonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:ef20a222-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.78']} DrugCentral uuid:ef20caae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32307 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:ef20f31c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.93']} DrugCentral uuid:ef211bb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:ef21448e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48044 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ef216d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:ef2195a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:ef21c238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:ef21c238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vasopressin targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:ef21f6e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:ef221f58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ef2247d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ef2274b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:ef2274b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:ef22aacc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:ef22aacc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:ef22aacc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:ef22eeba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:ef22eeba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:ef232146-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:ef232146-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:ef235b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ef235b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ef235b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ef235b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:ef23a850-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.051']} DrugCentral uuid:ef23d0fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.975']} DrugCentral uuid:ef23f990-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.652']} DrugCentral uuid:ef242230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:ef244b66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.554']} DrugCentral uuid:ef247406-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ef249c92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:ef24c50a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef24ee18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ef251744-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:ef253fc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venlafaxine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ef256848-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:ef258f44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:ef25b910-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ef25e192-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ef260dca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ef26371e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:ef265faa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.763']} DrugCentral uuid:ef26891c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:ef26b306-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:ef26dbb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:ef270450-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.201']} DrugCentral uuid:ef273132-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.594']} DrugCentral uuid:ef275b76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:ef2783e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:ef27ac98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ef27d51a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.88']} DrugCentral uuid:ef27fe5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:ef2826be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:ef284b08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (G protein-activated inward rectifier potassium channel 2) DrugCentral uuid:ef286f70-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.485']} DrugCentral uuid:ef289892-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) DrugCentral uuid:ef28bce6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ef28e57c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ef290f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96PR1 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ef293a68-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ef29634e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.348']} DrugCentral uuid:ef298bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:ef29b466-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:ef29dd60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:ef2a05f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:ef2a2e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ef2a575e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ef2a80d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:ef2aa952-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:ef2ad1fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:ef2afc0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:ef2b274c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.071']} DrugCentral uuid:ef2b5afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ef2b5afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ef2b5afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ef2ba21c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:ef2ba21c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:ef2ba21c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:ef2be13c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:ef2c09dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:ef2c32cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22462 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ef2c5c98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULQ1 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil is blocker of Ion channel (Two pore calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:ef2c8510-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NHX9 biolink:molecularly_interacts_with DrugCentral:2815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 verapamil is blocker of Ion channel (Two pore calcium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ef2cad92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vesnarinone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ef2cd86c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vesnarinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:ef2d02ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:2817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vesnarinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:ef2d337a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vesnarinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ef2d337a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vesnarinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ef2d67c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:2817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vesnarinone targets Enzyme (Transitional endoplasmic reticulum ATPase) DrugCentral uuid:ef2d8c3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vidarabine is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:ef2db08e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:2818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vidarabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:ef2dd4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:2818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vidarabine targets Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:ef2dfa30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:2818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vidarabine targets Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:ef2e1ef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:2818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vidarabine targets Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:ef2e4350-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16854 biolink:molecularly_interacts_with DrugCentral:2818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vidarabine targets Kinase (Deoxyguanosine kinase, mitochondrial) DrugCentral uuid:ef2e67ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P60891 biolink:molecularly_interacts_with DrugCentral:2818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vidarabine targets Kinase (Ribose-phosphate pyrophosphokinase 1) DrugCentral uuid:ef2e8d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vidarabine targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:ef2eb808-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04400 biolink:molecularly_interacts_with DrugCentral:2818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vidarabine targets Enzyme (Adenylate cyclase type V) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:ef2ee09e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50247 biolink:molecularly_interacts_with DrugCentral:2818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vidarabine targets Enzyme (Adenosylhomocysteinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:ef2f0952-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80404 biolink:molecularly_interacts_with DrugCentral:2819 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vigabatrin is inhibitor of Enzyme (4-aminobutyrate aminotransferase, mitochondrial) DrugCentral uuid:ef2f2e96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50554 biolink:molecularly_interacts_with DrugCentral:2819 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vigabatrin targets Enzyme (Gamma-amino-N-butyrate transaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:ef2f5790-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 viloxazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.76']} DrugCentral uuid:ef2f8030-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 viloxazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.81']} DrugCentral uuid:ef2fa8c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 viloxazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:ef2fd148-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 viloxazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:ef2ffa38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 viloxazine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ef3022f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 viloxazine is antagonist of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ef304b82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ef3079a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:ef309e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:ef30c256-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:ef30e6be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.728']} DrugCentral uuid:ef310fb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.298']} DrugCentral uuid:ef313f9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:ef31879a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ef31879a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ef31879a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ef31879a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ef31879a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ef31879a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ef31879a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ef31879a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ef31879a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ef321930-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ef3241da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:ef326e26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ef3296b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ef32bf34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:ef32e3ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:ef330836-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:ef332c80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:ef3358a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ef3358a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ef3358a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ef33b9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef33b9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef33b9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef33b9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef33b9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef33b9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef33b9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef33b9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef33b9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef343260-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2826 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vindesine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.607']} DrugCentral uuid:ef345af6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ef348378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.271']} DrugCentral uuid:ef34cb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef34cb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef34cb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef34cb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef34cb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef34cb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef34cb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef34cb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef34cb76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:ef353f98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinpocetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:ef3568d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:2828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinpocetine targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ef35915a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinpocetine is inhibitor of Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ef35bde2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinpocetine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:ef35bde2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2828 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinpocetine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:ef35f2c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Enzyme (11-cis retinol dehydrogenase) DrugCentral uuid:ef361760-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NR8 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Enzyme (Retinol dehydrogenase 12) DrugCentral uuid:ef363bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NBN7 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Enzyme (Retinol dehydrogenase 13) DrugCentral uuid:ef366026-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10745 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Surface antigen (Retinol-binding protein 3) DrugCentral uuid:ef368470-ac81-11ec-8b6b-0242ac110002 UniProtKB:P82980 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 5) DrugCentral uuid:ef36a91e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96R05 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Cytosolic other (Retinoid-binding protein 7) DrugCentral uuid:ef36cd90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:ef36f644-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50120 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 2) DrugCentral uuid:ef371a98-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94788 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Enzyme (Retinal dehydrogenase 2) DrugCentral uuid:ef373f96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00352 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Enzyme (Retinal dehydrogenase 1) DrugCentral uuid:ef3763e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12271 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Transporter (Retinaldehyde-binding protein 1) DrugCentral uuid:ef378974-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:ef37b20a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09455 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 1) DrugCentral uuid:ef37d8a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49116 biolink:molecularly_interacts_with DrugCentral:2831 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retinol is agonist of Nuclear other (Nuclear receptor subfamily 2 group C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:ef38044e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60779 biolink:molecularly_interacts_with DrugCentral:2832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamine targets Transporter (Thiamine transporter 1) DrugCentral uuid:ef3829d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29401 biolink:molecularly_interacts_with DrugCentral:2832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamine targets Enzyme (Transketolase) DrugCentral uuid:ef384e36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3S4 biolink:molecularly_interacts_with DrugCentral:2832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamine targets Kinase (Thiamin pyrophosphokinase 1) DrugCentral uuid:ef38737a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BU02 biolink:molecularly_interacts_with DrugCentral:2832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamine targets Enzyme (Thiamine-triphosphatase) DrugCentral uuid:ef3898dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51854 biolink:molecularly_interacts_with DrugCentral:2832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamine targets Enzyme (Transketolase-like protein 1) DrugCentral uuid:ef38bd4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ef38e602-ac81-11ec-8b6b-0242ac110002 UniProtKB:A2RI47 biolink:molecularly_interacts_with DrugCentral:2832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiamine targets Transporter (Thiamine transporter ThiT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.91']} DrugCentral uuid:ef390f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30043 biolink:molecularly_interacts_with DrugCentral:2834 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riboflavin targets Enzyme (Flavin reductase (NADPH)) DrugCentral uuid:ef39336e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969G6 biolink:molecularly_interacts_with DrugCentral:2834 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riboflavin targets Kinase (Riboflavin kinase) DrugCentral uuid:ef3957f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:2834 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riboflavin targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ef39808a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:2835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ef39ab46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40261 biolink:molecularly_interacts_with DrugCentral:2835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinic acid targets Enzyme (Nicotinamide N-methyltransferase) DrugCentral uuid:ef39d1ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15274 biolink:molecularly_interacts_with DrugCentral:2835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinic acid targets Enzyme (Nicotinate-nucleotide pyrophosphorylase [carboxylating]) DrugCentral uuid:ef39fa60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:2835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinic acid targets Enzyme (Nicotinamide phosphoribosyltransferase) DrugCentral uuid:ef3a1eb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80Z39 biolink:molecularly_interacts_with DrugCentral:2835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinic acid targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:ef3a4808-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EP66 biolink:molecularly_interacts_with DrugCentral:2835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinic acid targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ef3a7094-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:2835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinic acid targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:ef3a992a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:2835 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ef3ac1a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:2836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridoxine targets Enzyme (Serine hydroxymethyltransferase, cytosolic) DrugCentral uuid:ef3ae6c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NVS9 biolink:molecularly_interacts_with DrugCentral:2836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridoxine targets Enzyme (Pyridoxine-5'-phosphate oxidase) DrugCentral uuid:ef3b0b08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD0 biolink:molecularly_interacts_with DrugCentral:2836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridoxine targets Enzyme (Pyridoxal phosphate phosphatase) DrugCentral uuid:ef3b2f7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00764 biolink:molecularly_interacts_with DrugCentral:2836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridoxine targets Kinase (Pyridoxal kinase) DrugCentral uuid:ef3b53c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35520 biolink:molecularly_interacts_with DrugCentral:2836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridoxine targets Enzyme (Cystathionine beta-synthase) DrugCentral uuid:ef3b79a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y617 biolink:molecularly_interacts_with DrugCentral:2836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridoxine targets Enzyme (Phosphoserine aminotransferase) DrugCentral uuid:ef3b9fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:2838 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergocalciferol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:ef3bc430-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2838 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergocalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:ef3be898-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:2838 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ergocalciferol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:ef3c0d64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2840 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colecalciferol targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ef3c35be-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:2840 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colecalciferol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:ef3c5a4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2840 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colecalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.68']} DrugCentral uuid:ef3c82c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:2840 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colecalciferol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:ef3ca7ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02318 biolink:molecularly_interacts_with DrugCentral:2840 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colecalciferol targets Enzyme (Sterol 26-hydroxylase, mitochondrial) DrugCentral uuid:ef3ccc0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2841 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydrotachysterol targets Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:ef3cf08a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:2845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voglibose targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ef3d1aec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:2845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voglibose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ef3d4486-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:2845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voglibose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:ef3d700a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35574 biolink:molecularly_interacts_with DrugCentral:2845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voglibose targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:ef3d9a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:2845 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voglibose is inhibitor of Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ef3dc2f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voriconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ef3debd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voriconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['8.73']} DrugCentral uuid:ef3e146a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voriconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ef3e3cec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voriconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ef3e6578-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:2846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voriconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['5.844']} DrugCentral uuid:ef3e8eea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:2846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voriconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ef3eb802-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:2846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voriconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ef3ee084-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:2846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voriconazole targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:ef3f091a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:2846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voriconazole targets Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:ef3f349e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6A2 biolink:molecularly_interacts_with DrugCentral:2846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voriconazole targets Enzyme (Cholesterol 24-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ef3f5d7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2847 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 warfarin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.98']} DrugCentral uuid:ef3f8692-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2847 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 warfarin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.867']} DrugCentral uuid:ef3faf32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2847 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 warfarin is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ef3fd840-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16549 biolink:molecularly_interacts_with DrugCentral:2847 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 warfarin targets Enzyme (Proprotein convertase subtilisin/kexin type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:ef4000cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N0U8 biolink:molecularly_interacts_with DrugCentral:2847 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 warfarin targets Enzyme (Vitamin K epoxide reductase complex subunit 1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.284']} DrugCentral uuid:ef40296c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xamoterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.75']} DrugCentral uuid:ef4052ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xamoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:ef407b7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xamoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ef40a40a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ximelagatran targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ef40cd2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ximelagatran targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:ef40f6c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ximelagatran targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:ef41204c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:2852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ximelagatran targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:ef414d56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08709 biolink:molecularly_interacts_with DrugCentral:2852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ximelagatran targets Enzyme (Coagulation factor VII) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:ef4175ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04070 biolink:molecularly_interacts_with DrugCentral:2852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ximelagatran targets Enzyme (Vitamin K-dependent protein C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ef419eb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:2852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ximelagatran targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:ef41c74a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03951 biolink:molecularly_interacts_with DrugCentral:2852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ximelagatran targets Enzyme (Coagulation factor XI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ef41efd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ximelagatran targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ef421916-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2852 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ximelagatran is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:ef424256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.873']} DrugCentral uuid:ef426b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.114']} DrugCentral uuid:ef4296d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.646']} DrugCentral uuid:ef42c00a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:ef42e8d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47712 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Enzyme (Cytosolic phospholipase A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:ef43114a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:ef433af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:ef436406-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.419']} DrugCentral uuid:ef438d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.359']} DrugCentral uuid:ef43b5aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ef43dee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.452']} DrugCentral uuid:ef440802-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:ef4434d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef445de8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.269']} DrugCentral uuid:ef448660-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:ef44b1b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:ef44da5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ef4502de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ef452c6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:ef455572-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:ef457e12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zafirlukast targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:ef45a680-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:2856 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zalcitabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:ef45cafc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2856 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zalcitabine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:ef45fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:ef45fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:ef45fbee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:ef4642b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:ef4642b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:ef4642b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:ef46828a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16207 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ef46ab16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ef46d41a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:ef46fcba-ac81-11ec-8b6b-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:ef4725b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75VQ4 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:ef474e36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6Q793 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ef4776d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:ef479f80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2LFS1 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ef47c956-ac81-11ec-8b6b-0242ac110002 UniProtKB:C4LRQ6 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ef47f1f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q20MD3 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ef481a8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:ef484430-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:ef486d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ49 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Sialidase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:ef48957a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3R4 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Sialidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ef48c00e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07599 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:ef48e8f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3S340 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:ef491216-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WWR8 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Sialidase-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.58']} DrugCentral uuid:ef493aac-ac81-11ec-8b6b-0242ac110002 UniProtKB:D5F1R0 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:ef4967de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.76']} DrugCentral uuid:ef4990ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XV28 biolink:molecularly_interacts_with DrugCentral:2859 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:ef49b964-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:ef49e1dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ef4a0a72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ef4a3650-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23919 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ef4a61f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ef4a8cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:ef4ab5d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03362 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets Polyprotein (Gag-Pro-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:ef4aded4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72549 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:ef4b0760-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:ef4b3604-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ef4b5fbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9PPP5 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ef4b8852-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:2861 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zidovudine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ef4bb0f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:2862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zileuton is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ef4bd988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:2862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zileuton targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ef4c06b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zileuton targets GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:ef4c2f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:2862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zileuton targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.071']} DrugCentral uuid:ef4c57be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:2862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zileuton targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:ef4c8040-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20292 biolink:molecularly_interacts_with DrugCentral:2862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zileuton targets Cytosolic other (Arachidonate 5-lipoxygenase-activating protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:ef4ca94e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zileuton targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:ef4cd1e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zileuton targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ef4cfb56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48999 biolink:molecularly_interacts_with DrugCentral:2862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zileuton targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:ef4d24aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zileuton targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:ef4d4d36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zimeldine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.727']} DrugCentral uuid:ef4d759a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zimeldine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:ef4d9e94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zimeldine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:ef4dc86a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:ef4df3e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:ef4e1cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:ef4e454c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:ef4e6e3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ef4e96c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:ef4ebf54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:ef4ee902-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:ef4f1314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:ef4f3baa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ef4f6440-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.565']} DrugCentral uuid:ef4f8ccc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:ef4fb65c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ef4fdf06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ef5007a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ef5030aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:ef505940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:ef5081e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:ef50aa76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:ef50d618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:ef5100d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:ef512960-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:ef515200-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ef517bb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:ef51a444-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:ef51ccee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ef51f584-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ef521e92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.114']} DrugCentral uuid:ef52471e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:ef526b86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ef52941c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ef52bd66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:ef52e5fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.536']} DrugCentral uuid:ef530e92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ef533732-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ef5360ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:ef53893a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:ef53b1c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:ef53daca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ef540360-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:ef54338a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ef54338a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ef54338a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ef54734a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziprasidone targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ef549bea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zofenopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ef54c598-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:2866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zofenopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ef54ef46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zofenopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:ef551868-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:ef554112-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ef5569b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ef559248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:ef55bb74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ef55e3f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:ef560caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50281 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Matrix metalloproteinase-14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ef5635d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:ef565f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:ef5687ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ef56b042-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22939 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ef56d8c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ef57027c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12051 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ef572b12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ef5753a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00481 biolink:molecularly_interacts_with DrugCentral:2868 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zoledronic acid targets Unclassified (Butyrophilin subfamily 3 member A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:ef577c02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ef57a510-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolmitriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ef57cdba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolmitriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:ef57f664-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:ef581fb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ef584876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolmitriptan targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.4']} DrugCentral uuid:ef587102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolmitriptan targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:ef58a168-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ef58a168-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ef58a168-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:ef58e52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:ef590dce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:ef593682-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ef595f72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.703']} DrugCentral uuid:ef598826-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:ef59b0bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:ef59d97a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:ef5a02e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19969 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:ef5a3352-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:ef5a3352-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:ef5a3352-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:ef5a7bb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:ef5a7bb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:ef5a7bb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:ef5ac826-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:ef5ac826-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:ef5ac826-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:ef5b1236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:ef5b1236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:ef5b1236-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5b8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:ef5c680c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ef5c680c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ef5c680c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:ef5cb53c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ef5cb53c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ef5cb53c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ef5cfcae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:ef5cfcae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:ef5cfcae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:ef5d43da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:ef5d43da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:ef5d43da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:ef5d8d2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:ef5d8d2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:ef5d8d2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:ef5dccec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:2870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zolpidem targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:ef5df578-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2871 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zomepirac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:ef5e1e04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2871 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zomepirac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.367']} DrugCentral uuid:ef5e4cbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2871 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zomepirac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ef5e4cbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2871 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zomepirac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:ef5e84b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:ef5eaa9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:ef5ed36c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:ef5ef7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.252']} DrugCentral uuid:ef5f207e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef5f4928-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ef5f725e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:ef5f9b08-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:ef5fc39e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:ef5fec3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:ef601646-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:ef60421a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:ef606b28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:ef6093be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ef60bce0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ef60e576-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:ef610e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:ef6137a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ef6160f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:ef6189b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:ef61b258-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:ef61daee-ac81-11ec-8b6b-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:ef6206ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:ef623156-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:ef625a0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:ef628322-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef62abb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:ef62d462-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:ef630176-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:ef630176-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:ef633768-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:ef635ffe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6NSN2 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:ef638894-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:ef63b120-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:ef63dd44-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2872 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zonisamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef643f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef651ba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:ef651ba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:ef651ba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:ef6562ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:ef6562ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:ef6562ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:ef65acd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:ef65acd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:ef65acd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:ef65f3e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:ef65f3e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:ef65f3e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:ef663b2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:ef663b2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:ef663b2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:ef66840e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:ef66840e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:ef66840e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:ef66cbf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:ef66cbf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:ef66cbf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:ef6712fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:ef6712fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:ef6712fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:ef67523a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.394']} DrugCentral uuid:ef677b84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:ef67a438-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef67cc9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ef67f514-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.686']} DrugCentral uuid:ef681e04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:ef68469a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ef686f1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ef689852-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:ef68c0e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:ef68e97e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:ef69120a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ef693bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:ef6967c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.273']} DrugCentral uuid:ef6990e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:ef69b94e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.606']} DrugCentral uuid:ef69e310-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:ef6a0b88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:ef6a33f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.704']} DrugCentral uuid:ef6a5c6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:ef6a8626-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:ef6aaea8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:ef6ad72a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:ef6affb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.585']} DrugCentral uuid:ef6b2ba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:ef6b5772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:ef6b831e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.016']} DrugCentral uuid:ef6bae70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.441']} DrugCentral uuid:ef6bd710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:ef6c00be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.326']} DrugCentral uuid:ef6c294a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:ef6c528a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:ef6c7b34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:ef6ca3ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ef6ccc56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:ef6cf73a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zuclopenthixol targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:ef6d1bf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zuclopenthixol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:ef6d447e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zuclopenthixol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:ef6d68fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zuclopenthixol is antagonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:ef6d8dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zuclopenthixol is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:ef6db238-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:2878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) DrugCentral uuid:ef6dd6a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02294 biolink:molecularly_interacts_with DrugCentral:2878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:ef6e0030-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54282 biolink:molecularly_interacts_with DrugCentral:2878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:ef6e295c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotarolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:ef6e51d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zotarolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:ef6e7a56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2955 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eledoisin is agonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:ef6ea2e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29371 biolink:molecularly_interacts_with DrugCentral:2955 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eledoisin targets GPCR (Neuromedin-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.66']} DrugCentral uuid:ef6ecd1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gonadorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ef6ef5c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:2958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gonadorelin targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ef6f1e3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16235 biolink:molecularly_interacts_with DrugCentral:2958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gonadorelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:ef6f4f58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:ef6f4f58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:ef6f4f58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:ef6f87f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:2960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mifamurtide is activator of Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) DrugCentral uuid:ef6fac64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96EB6 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Enzyme (NAD-dependent protein deacetylase sirtuin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:ef6fd4e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15077 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['4']} DrugCentral uuid:ef6ffe1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47900 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ef7026b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IXJ6 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Enzyme (NAD-dependent protein deacetylase sirtuin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ef704f34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:ef7077a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ef70a2e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:ef70ce64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ef70f9b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:ef71226a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ef714b5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5VLE3 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Enzyme (RmtA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:ef7173be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.749']} DrugCentral uuid:ef719c68-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15648 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (ATP-dependent 6-phosphofructokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef71ed08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef728c36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.963']} DrugCentral uuid:ef72b80a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:ef72e0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80Z26 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Enzyme (Nucleoside triphosphate diphosphohydrolase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:ef73099a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35795 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Enzyme (Ectonucleoside triphosphate diphosphohydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:ef73324e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49654 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:ef735ae4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49653 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:ef73837a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47824 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ef73acb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51578 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ef73d550-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42224 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 1-alpha/beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:ef73fdfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42229 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:ef7426b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51692 biolink:molecularly_interacts_with DrugCentral:2966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 5B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:ef74528c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2968 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triptorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.025']} DrugCentral uuid:ef747cd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:2968 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triptorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:ef74a570-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxacurium targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:ef74c9c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxacurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:ef74f75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:ef74f75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:ef74f75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:ef752f90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2975 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 histrelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:ef7553f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:2977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caspofungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:ef757d2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4WLT4 biolink:molecularly_interacts_with DrugCentral:2977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caspofungin is inhibitor of Enzyme (1,3-beta-glucan synthase catalytic subunit FksP) DrugCentral uuid:ef75a1aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O13383 biolink:molecularly_interacts_with DrugCentral:2977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caspofungin targets Unclassified (1,3-beta-D-glucan synthase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:ef75ce3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.65']} DrugCentral uuid:ef75ce3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.65']} DrugCentral uuid:ef760712-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.873']} DrugCentral uuid:ef760712-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.873']} DrugCentral uuid:ef76416e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.499']} DrugCentral uuid:ef76416e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.499']} DrugCentral uuid:ef7676c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30988 biolink:molecularly_interacts_with DrugCentral:2989 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Calcitonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.086']} DrugCentral uuid:ef769f4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['12.7']} DrugCentral uuid:ef76c83c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:ef76f0e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47871 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon is agonist of GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:ef771968-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30082 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:ef775e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:ef775e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:ef775e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:ef775e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:ef775e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:ef775e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:ef775e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:ef775e1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:ef77d614-ac81-11ec-8b6b-0242ac110002 UniProtKB:F8V479 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:ef780274-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35659 biolink:molecularly_interacts_with DrugCentral:2994 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glucagon targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.36']} DrugCentral uuid:ef782e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2995 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lepirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['13']} DrugCentral uuid:ef7859e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ef7882b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef78ab52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:ef78d3d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.1']} DrugCentral uuid:ef78fc74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:ef7934f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ef7934f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ef7934f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ef7934f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ef7934f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ef799a1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ef799a1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ef799a1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ef799a1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ef799a1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:ef79f3b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.46']} DrugCentral uuid:ef7a1c76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:ef7a452a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:ef7a6e4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:ef7a970a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:2997 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:ef7ac0b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96529 biolink:molecularly_interacts_with DrugCentral:2999 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrantel targets Enzyme (Acetylcholinesterase) DrugCentral uuid:ef7ae516-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:3008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atosiban targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:ef7b0e60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:3008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atosiban targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:ef7b3804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:3008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atosiban targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:ef7b609a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:3008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atosiban targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:ef7b8ab6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:3008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atosiban is antagonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:ef7bb694-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:ef7be5ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ef7be5ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ef7be5ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:ef7c2584-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.934']} DrugCentral uuid:ef7c4e38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:ef7c76ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.888']} DrugCentral uuid:ef7c9fa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.046']} DrugCentral uuid:ef7cc8d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:ef7cf18a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.269']} DrugCentral uuid:ef7d1a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.532']} DrugCentral uuid:ef7d4374-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.004']} DrugCentral uuid:ef7d6e30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:ef7d96c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.092']} DrugCentral uuid:ef7dbf5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:ef7de806-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:ef7e1114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:ef7e39dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.965']} DrugCentral uuid:ef7e6290-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.649']} DrugCentral uuid:ef7e8b3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.115']} DrugCentral uuid:ef7eb498-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.681']} DrugCentral uuid:ef7edd10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.192']} DrugCentral uuid:ef7f06b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:ef7f306c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969F8 biolink:molecularly_interacts_with DrugCentral:3018 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzethonium targets GPCR (KiSS-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:ef7f595c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bergapten targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:ef7f81f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:3021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bergapten targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:ef7faa88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3021 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bergapten targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:ef7fd382-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3025 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:ef7ffc22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3025 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:ef8024ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3025 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:ef804d44-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.299']} DrugCentral uuid:ef8077ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.651']} DrugCentral uuid:ef80a05a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:ef80c8dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.843']} DrugCentral uuid:ef80f15e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.912']} DrugCentral uuid:ef811c9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.501']} DrugCentral uuid:ef814776-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.365']} DrugCentral uuid:ef817020-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:ef8198a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:ef81c1ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.844']} DrugCentral uuid:ef81ea46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.195']} DrugCentral uuid:ef8212fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.761']} DrugCentral uuid:ef823c44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:ef8264ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ef828e1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ef82b6a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.212']} DrugCentral uuid:ef82dfe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.647']} DrugCentral uuid:ef830980-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:ef8331f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.735']} DrugCentral uuid:ef835a84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.498']} DrugCentral uuid:ef83836a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:ef83ac00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.809']} DrugCentral uuid:ef83d4a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.415']} DrugCentral uuid:ef83fd22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ef842676-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:ef844f16-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:ef8477ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:ef84a038-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ef84cbe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:ef84f45c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ef851cde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:ef854556-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6IQ20 biolink:molecularly_interacts_with DrugCentral:3032 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bithionol is inhibitor of Unclassified (N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:ef856e32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:3042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 broxuridine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ef8596c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:3042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 broxuridine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ef85bf5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:3047 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufexamac is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.97']} DrugCentral uuid:ef85e88a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:3047 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufexamac is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.91']} DrugCentral uuid:ef861134-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3047 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufexamac targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:ef8639a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:3047 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufexamac targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:ef8669ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ef8669ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ef8669ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:ef86b77e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:ef86b77e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:ef86b77e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:ef86f7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:ef8722d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:ef874b62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:ef8773e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:ef879c7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:ef87c5f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54577 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin targets Enzyme (Tyrosine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:ef87eeaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35433 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ef881740-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03887 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin targets Unclassified (NADH-ubiquinone oxidoreductase chain 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:ef884062-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R4D5 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin targets Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:ef886a2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q704Y3 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin is activator of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:ef8892ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ef88bb50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16388 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:ef88e3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63142 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:ef890d44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capsaicin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:ef8935d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:ef895e48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:3066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:ef8986de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NJH6 biolink:molecularly_interacts_with DrugCentral:3066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbaryl targets Unclassified (Ace-orthologous acetylcholinesterase; Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:ef89afe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7YWJ9 biolink:molecularly_interacts_with DrugCentral:3066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:ef89d882-ac81-11ec-8b6b-0242ac110002 UniProtKB:K4JQ36 biolink:molecularly_interacts_with DrugCentral:3066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:ef8a010e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05181 biolink:molecularly_interacts_with DrugCentral:3067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbon tetrachloride targets Enzyme (Cytochrome P450 2E1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.959']} DrugCentral uuid:ef8a2a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31327 biolink:molecularly_interacts_with DrugCentral:3068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carglumic acid is positive allosteric modulator of Enzyme (Carbamoyl-phosphate synthase [ammonia], mitochondrial) DrugCentral uuid:ef8a56f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:ef8a56f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:ef8a56f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:ef8a977c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05193 biolink:molecularly_interacts_with DrugCentral:3082 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetrimonium targets Structural (Dynamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:ef8ac008-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:3083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetylpyridinium targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:ef8ae952-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42575 biolink:molecularly_interacts_with DrugCentral:3083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetylpyridinium targets Enzyme (Caspase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:ef8b11c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroxylenol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.928']} DrugCentral uuid:ef8b3a74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chloroxylenol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.738']} DrugCentral uuid:ef8b6378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:3095 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorquinaldol targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ef8b8c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:3096 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cholic acid targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:ef8bb490-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:3096 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cholic acid is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:ef8bdd12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:ef8c0814-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ef8c3780-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:ef8c3780-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:ef8c6f66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:ef8c6f66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:ef8ca800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:ef8ca800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:ef8cdfe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:ef8cdfe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:ef8d17b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:ef8d17b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:ef8d4c06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28570 biolink:molecularly_interacts_with DrugCentral:3097 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline targets Transporter (Creatine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:ef8d7492-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:3101 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinchophen targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.9']} DrugCentral uuid:ef8d9e22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q695T7 biolink:molecularly_interacts_with DrugCentral:3102 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cinromide is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:ef8dc73a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:ef8df214-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxiquine targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:ef8e1a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:3114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxiquine targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:ef8e430e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:3114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cloxiquine targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ef8e7414-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef8e7414-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef8e7414-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef8eb33e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:3124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cynarine targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ef8edbd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:3126 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 demoxytocin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:ef8f1072-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ef8f1072-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ef8f1072-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ef8f1072-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:ef8f5adc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3135 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:ef8f7f44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dibrompropamidine targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:ef8fa88e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dibrompropamidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:ef8fd174-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:3137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dibrompropamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:ef8ffa0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:3137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dibrompropamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ef9022a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 difluprednate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:ef904faa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ef904faa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ef904faa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:ef908ed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3157 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diosmin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:ef90b88c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3157 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diosmin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:ef90e280-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:3158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dioxadrol targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:ef910b3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:3162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disufenton targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef9133b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:3162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 disufenton targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:ef915c56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:3165 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domitroban is antagonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:ef918640-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30987 biolink:molecularly_interacts_with DrugCentral:3165 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 domitroban is antagonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:ef91aefe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3170 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:ef91d7a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3170 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:ef920034-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3170 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:ef922974-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3170 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.6']} DrugCentral uuid:ef925214-ac81-11ec-8b6b-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:3173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edoxudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ef927a78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eicosapentaenoic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:ef92a2f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:ef92cbb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef92f43a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ef931cda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:ef934548-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eicosapentaenoic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:ef9370ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eicosapentaenoic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:ef9399a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:3174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eicosapentaenoic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:ef93c2ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDS5 biolink:molecularly_interacts_with DrugCentral:3174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eicosapentaenoic acid targets GPCR (Oxoeicosanoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef93eb56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eicosapentaenoic acid targets Nuclear other (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:ef94146e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3177 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enilconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:ef943d04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:ef946586-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:ef948e8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:ef94bafe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:ef94e38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.91']} DrugCentral uuid:ef950c0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:ef9535ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00489 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Glycogen phosphorylase, muscle form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:ef955e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:ef958704-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:ef95af90-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:ef95d876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16232 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:ef960102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50233 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:ef962984-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:ef965206-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:ef967ea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:ef96a882-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:ef96d118-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9CPU0 biolink:molecularly_interacts_with DrugCentral:3178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxolone targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:ef96fab2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eseridine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:ef9723a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eseridine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:ef974c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:3186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eseridine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:ef9774a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:ef979dc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.748']} DrugCentral uuid:ef97c8e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:ef97f3e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol is agonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:ef981c76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ef984570-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.63']} DrugCentral uuid:ef986e1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.064']} DrugCentral uuid:ef9896ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:3187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:ef98c04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:3187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estriol targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:ef98ea2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:ef99134c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.062']} DrugCentral uuid:ef993be2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:ef996496-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:ef998dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:ef99b662-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:ef99deda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:ef9a07d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:ef9a306a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:ef9a5914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:ef9a8196-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.181']} DrugCentral uuid:ef9aab6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:ef9ad3ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:3194 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethacridine targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:ef9afc84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:3194 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethacridine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:ef9b24f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:ef9b4df6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:ef9b7682-ac81-11ec-8b6b-0242ac110002 UniProtKB:P39086 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:ef9b9f0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:ef9bc790-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:ef9bf094-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:ef9c1920-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13002 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:ef9c41c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13003 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:ef9c6a6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19491 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:ef9c95b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:ef9cc352-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16099 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:ef9ceef4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42260 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:ef9d1af0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22756 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:ef9d437c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19490 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:ef9d6c12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19492 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:ef9d94b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:ef9dbd98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01812 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:ef9de61a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:ef9e0ea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42264 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:ef9e42c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:ef9e42c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:ef9e42c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:ef9e42c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:ef9e9df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:ef9e9df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:ef9e9df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:ef9e9df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:ef9e9df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:ef9efbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ef9efbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ef9efbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:ef9f51e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ef9f51e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ef9f51e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ef9f51e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ef9f51e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ef9f51e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ef9f51e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:ef9fbfda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 evans blue targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:ef9fe866-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25044 biolink:molecularly_interacts_with DrugCentral:3217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 evans blue targets Enzyme (Tyrosine-protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:efa010f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7TSF2 biolink:molecularly_interacts_with DrugCentral:3217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 evans blue targets Transporter (Vesicular glutamate transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:efa03b2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13822 biolink:molecularly_interacts_with DrugCentral:3217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 evans blue targets Enzyme (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:efa063ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08659 biolink:molecularly_interacts_with DrugCentral:3217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 evans blue targets Unclassified (Luciferin 4-monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:efa08c12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:3219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 exisulind targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.217']} DrugCentral uuid:efa0b4a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 exisulind targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:efa0ddc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:3219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 exisulind targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.859']} DrugCentral uuid:efa10624-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:efa12ea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:efa15868-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:efa18158-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.641']} DrugCentral uuid:efa1a9ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.377']} DrugCentral uuid:efa1d266-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:efa1fbd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.824']} DrugCentral uuid:efa2245a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:efa24cfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.328']} DrugCentral uuid:efa27586-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:efa29e9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.688']} DrugCentral uuid:efa2c72a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:efa2efca-ac81-11ec-8b6b-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:3220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 femoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:efa31860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05121 biolink:molecularly_interacts_with DrugCentral:3224 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fendosal is inhibitor of Secreted (Plasminogen activator inhibitor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:efa34236-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenoxazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:efa36acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04303 biolink:molecularly_interacts_with DrugCentral:3227 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenticlor targets Enzyme (Uracil-DNA glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:efa39362-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:3229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fumaric acid targets Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:efa3bbd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:3236 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flusalan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:efa3e6e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:3236 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flusalan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:efa40f72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:3236 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flusalan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:efa43bf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosfestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:efa43bf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosfestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa49942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:efa534f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3253 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fumagillin targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:efa55ddc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:efa58672-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:efa5afd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:efa5d9a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:efa602be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:efa62b54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:efa65570-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:efa67e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:efa6a674-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:efa6cf14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:efa6f7fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08590 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:efa7209a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:efa74926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:efa771b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:efa79c64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15661 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate is inhibitor of Enzyme (Tryptase alpha/beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:efa7c4dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:3257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabexate targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:efa7ed5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:efa81680-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:efa83f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:efa867a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:efa89038-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentisic acid targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:efa8b914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:efa8e1b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:efa90a36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3275 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamidine targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:efa932c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3275 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:efa95d4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:3275 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:efa988bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:3275 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:efa9b3fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:3275 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hexamidine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:efa9dc9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:efaa05c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:efaa2e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:efaa56f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:efaa8082-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:efaaa972-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:efaad1f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:efaafa8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:efab23ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:efab4c6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:efab7582-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.91']} DrugCentral uuid:efab9e18-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:efabc73a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:efabf11a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:3282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:efac19a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:3290 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyquinoline targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.89']} DrugCentral uuid:efac425a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:3290 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:efac6b36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3290 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyquinoline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:efac93b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:3290 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:efacbc30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:3290 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyquinoline targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:eface49e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01693 biolink:molecularly_interacts_with DrugCentral:3290 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxyquinoline targets Enzyme (Bacterial leucyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:efad0e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:3293 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibufenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:efad36f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:efad5f96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.969']} DrugCentral uuid:efad8822-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:efadb162-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:efadd9c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:efae0252-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.181']} DrugCentral uuid:efae2af2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.859']} DrugCentral uuid:efae53ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.227']} DrugCentral uuid:efae7d36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:efaea5b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:efaecf3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:efaef7b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:efaf202e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:efaf48b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.496']} DrugCentral uuid:efaf718c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:efaf9a22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:efafc2ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:efafeb44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:efb0140c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:efb03ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:efb0651a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.79']} DrugCentral uuid:efb08db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:efb0b934-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:efb0e3a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:efb10c22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:efb134a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:efb15dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:efb18648-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:efb1aed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:efb1d904-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:efb2019a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:efb22a26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:efb25a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:efb25a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:efb25a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:efb2a046-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:3309 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:efb2cbac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3309 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isoconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:efb2f73a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:3312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:efb3205c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:3312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:efb348d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O88703 biolink:molecularly_interacts_with DrugCentral:3312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:efb37160-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60741 biolink:molecularly_interacts_with DrugCentral:3312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:efb399f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL51 biolink:molecularly_interacts_with DrugCentral:3312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) DrugCentral uuid:efb3bed6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P1Z3 biolink:molecularly_interacts_with DrugCentral:3312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:efb3e76c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 khellin targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:efb40fee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:3317 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenalidomide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.886']} DrugCentral uuid:efb4385c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:3317 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:efb4644e-ac81-11ec-8b6b-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:3317 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:efb48d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:3317 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.527']} DrugCentral uuid:efb4b5c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:efb4de38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:efb50732-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:efb52fbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:efb55854-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efb58144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05413 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets Cytosolic other (Fatty acid-binding protein, heart) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:efb5a9ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:efb5d27a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:efb5fb06-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14721 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid is activator of Ion channel (Potassium voltage-gated channel subfamily B member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:efb62612-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:efb64fc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efb67824-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:efb6a0ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:efb6c9be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5NUL3 biolink:molecularly_interacts_with DrugCentral:3323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linoleic acid is agonist of GPCR (Free fatty acid receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:efb6f254-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:3325 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lodoxamide is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.793']} DrugCentral uuid:efb71ad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:3328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lubeluzole targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:efb74358-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:3328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lubeluzole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:efb76c48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mestanolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:efb791d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mestanolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.81']} DrugCentral uuid:efb7ba5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesterolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.6']} DrugCentral uuid:efb7e394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mesterolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:efb80d24-ac81-11ec-8b6b-0242ac110002 UniProtKB:O34667 biolink:molecularly_interacts_with DrugCentral:3347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methionine targets Unclassified (S-ribosylhomocysteine lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:efb835ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyltestosterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.077']} DrugCentral uuid:efb85e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyltestosterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.66']} DrugCentral uuid:efb886e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyltestosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:efb8affe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyltestosterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:efb8d876-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyltestosterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:efb90102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17708 biolink:molecularly_interacts_with DrugCentral:3362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoguazone targets Enzyme (S-adenosylmethionine decarboxylase proenzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efb929de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36633 biolink:molecularly_interacts_with DrugCentral:3362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mitoguazone targets Enzyme (Amiloride-sensitive amine oxidase [copper-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:efb95652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxestrol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:efb95652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxestrol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:efb98a64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:efb9b304-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:efb9dcb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:efba0642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:efba2ec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:efba5f0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:efba5f0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:efba5f0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:efbaa642-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:efbaa642-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:efbaa642-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:efbaf890-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:efbaf890-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:efbaf890-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:efbaf890-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:efbaf890-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:efbaf890-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:efbb59b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:3377 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neridronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:efbb8242-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nifenalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.88']} DrugCentral uuid:efbbac72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octopamine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:efbbd4e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:efbbfd3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:3396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:efbc25a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:3396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:efbc4e98-ac81-11ec-8b6b-0242ac110002 UniProtKB:H9TVJ1 biolink:molecularly_interacts_with DrugCentral:3396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octopamine targets GPCR (TyR1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:efbc7846-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01705 biolink:molecularly_interacts_with DrugCentral:3399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleandrin targets Unclassified (Neurogenic locus notch homolog protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:efbca0b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:efbcc936-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:efbcf226-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:efbd1bac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:efbd442e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:efbd6cc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:efbd965e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:efbdbecc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01469 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Cytosolic other (Fatty acid-binding protein, epidermal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:efbde7ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:efbe10f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:efbe396a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07148 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:efbe6200-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:efbe8a82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:efbeb34a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:efbedbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5NUL3 biolink:molecularly_interacts_with DrugCentral:3400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oleic acid is agonist of GPCR (Free fatty acid receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:efbf0444-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5T6X5 biolink:molecularly_interacts_with DrugCentral:3401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ornithine is agonist of GPCR (G-protein coupled receptor family C group 6 member A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:efbf3496-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:efbf3496-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:efbf3496-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:efbf74c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.684']} DrugCentral uuid:efbf9d6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.815']} DrugCentral uuid:efbfc60e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.046']} DrugCentral uuid:efbfef12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.372']} DrugCentral uuid:efc017b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.723']} DrugCentral uuid:efc0405c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:efc06906-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.925']} DrugCentral uuid:efc09228-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.533']} DrugCentral uuid:efc0bbc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.778']} DrugCentral uuid:efc0e480-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.169']} DrugCentral uuid:efc10d20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.943']} DrugCentral uuid:efc138fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:efc16194-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.449']} DrugCentral uuid:efc18a48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:efc1b2f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.676']} DrugCentral uuid:efc1dbd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc2045a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.445']} DrugCentral uuid:efc22d04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:efc25310-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.728']} DrugCentral uuid:efc27ba6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.333']} DrugCentral uuid:efc2a43c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:efc2ccc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:efc2f702-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.209']} DrugCentral uuid:efc31fde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:efc34860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.969']} DrugCentral uuid:efc370d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:efc39a54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:3412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxybenzone targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:efc3c2d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:3413 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycinchophen targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:efc3eb4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:3413 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxycinchophen targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.82']} DrugCentral uuid:efc413d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:efc43cca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine is modulator of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.76']} DrugCentral uuid:efc46538-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.658']} DrugCentral uuid:efc48dba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.307']} DrugCentral uuid:efc4b722-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:efc4e364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:efc50e98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:efc5372e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.27']} DrugCentral uuid:efc56bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:efc56bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:efc56bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:efc56bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:efc5be10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:efc5be10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:efc5be10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:efc5fdb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3467 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picloxydine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:efc6265c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:3467 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 picloxydine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:efc64ef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:3474 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adipic acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:efc67788-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:efc6a1a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:efc6ca6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:efc6f2ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:efc71b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04015 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Unclassified (Regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:efc7447e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02550 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:efc76d0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03118 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Unclassified (Regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.98']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc7cb6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efc89da6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:efc89da6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:efc89da6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:efc8e0a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:efc8e0a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:efc91510-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03120 biolink:molecularly_interacts_with DrugCentral:3481 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 podophyllotoxin targets Unclassified (Human papillomavirus regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.15']} DrugCentral uuid:efc93dc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polyestradiol phosphate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:efc96218-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 posaconazole targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:efc98680-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:3483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 posaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['9.398']} DrugCentral uuid:efc9af98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:3483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 posaconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:efc9d82e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:3483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 posaconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:efca015a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7Z1V1 biolink:molecularly_interacts_with DrugCentral:3483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 posaconazole targets Enzyme (Sterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:efca2a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:3483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 posaconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:efca5434-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:3486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 practolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:efca7cf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:3486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:efcaa682-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.69']} DrugCentral uuid:efcacf2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:3486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 practolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:efcaf830-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:3486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 practolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.98']} DrugCentral uuid:efcb20c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18762 biolink:molecularly_interacts_with DrugCentral:3486 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:efcb4970-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramocaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.292']} DrugCentral uuid:efcb7210-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:3487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramocaine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.199']} DrugCentral uuid:efcba302-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:efcba302-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:efcba302-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:efcbe380-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:3493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:efcc0c16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:3493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:efcc4000-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:efcc4000-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:efcc4000-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:efcc7f02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:3500 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protoporphyrin targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:efcca75c-ac81-11ec-8b6b-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:3500 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 protoporphyrin targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:efccd02e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3502 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prucalopride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.629']} DrugCentral uuid:efccf8c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3502 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prucalopride targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:efcd2164-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:3502 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prucalopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:efcd49fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:3502 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prucalopride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:efcd72f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:3505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 homonicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:efcd9b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51575 biolink:molecularly_interacts_with DrugCentral:3506 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridoxal phosphate targets Ion channel (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:efcdc3e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:efcdedd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:efce1862-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:efce41e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:efce6a7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:efce9378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:efcebc0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:efcee4cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:efcf0d62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:efcf3706-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:efcf5fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:efcf883c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:efcfb0dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:efcfdb66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:efd003fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:3508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:efd02c9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrovalerone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:efd05528-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrovalerone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:efd07e4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3511 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrovalerone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:efd0a6d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:efd0cf58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:efd0f83e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:efd120de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:efd14974-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:efd1734a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:efd19cd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:efd1c566-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:efd1edde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:efd21700-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:efd248a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:efd248a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:efd248a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:efd287d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:efd2b048-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:efd2d99c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:efd3021e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:efd32aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:efd35340-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:efd37e56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:efd3a728-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:efd3cf96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:efd3f82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:efd4211c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:efd44a2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:efd472b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:efd49b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:efd4c432-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:efd4ecbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:efd5155e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:efd53f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:efd56ab8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:efd59344-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:efd5bbc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:efd5e4ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:efd60d38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:efd6370e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:efd65f86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:efd6886c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:efd6b0ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:efd6d95c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:efd701e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:efd72d6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:efd757b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:efd78046-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:efd7a8f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:efd7d1ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04745 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Alpha-amylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:efd7fa76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:efd8230c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:efd84c06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:efd87492-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:efd89d32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08254 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Stromelysin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:efd8c5aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:efd8efb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:efd91b2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:efd9457a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:efd96df2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48147 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Prolyl endopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:efd996e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:efd9bf64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:efd9e7dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:efda1068-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:efda3a7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:efda6392-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:efda8c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:efdab478-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04054 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Phospholipase A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:efdadfb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:efdb0842-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:efdb30ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P39900 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Macrophage metalloelastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:efdb59c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45452 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Collagenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:efdb8254-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17538 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Chymotrypsinogen B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:efdbaaea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:efdbd38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:efdbfc5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:efdc24f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80276 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:efdc4d6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:efdc75e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06737 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Glycogen phosphorylase, liver form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:efdca09e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15046 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Lysine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:efdcc9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:efdcf224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:efdd1ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:efdd438c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:efdd6d58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:efdd95da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:efddbe52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:efdde738-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:efde0fc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:efde386e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:efde61f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:efde8d1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:efdeb5b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:efdede36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:efdf073a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:efdf2fbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:efdf5852-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:efdf80d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q965D5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Enoyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:efdfa9b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:efdfd228-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q91WR5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Aldo-keto reductase family 1 member C21) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:efdffab4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:efe02318-ac81-11ec-8b6b-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:efe04e10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:efe076ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:efe09fdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:efe0c84a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:efe0f126-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:efe11994-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:efe1422a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:efe16ac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:efe193c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:efe1bc5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:efe1e4d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10584 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Malate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:efe20e30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21588 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (5'-nucleotidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:efe236d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q965D6 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (3-oxoacyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:efe26038-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q965D7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Beta-hydroxyacyl-ACP dehydratase; Fatty acid synthesis protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:efe288ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27986 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Phosphatidylinositol 3-kinase regulatory subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:efe2b1b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPH5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (NADPH oxidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:efe2da36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:efe302b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:efe32b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:efe357d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q1CTD3 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (D-alanine--D-alanine ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:efe384fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC98 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase Nek6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:efe3ad9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96394 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Arginase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:efe3d9fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:efe3d9fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:efe413d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15078 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 5/CDK5 activator 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:efe413d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15078 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 5/CDK5 activator 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:efe45366-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:efe45366-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:efe45366-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:efe45366-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:efe4a21c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:efe4a21c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:efe4d9da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:efe4d9da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:efe50dd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:efe5372c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29477 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:efe55fae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00796 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Sorbitol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:efe58844-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99895 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Chymotrypsin C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:efe5b1ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03114 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Cell division protein kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:efe5ddda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:efe60918-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07862 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (D-alanylalanine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:efe631ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:efe65a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01062 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Phosphodiesterase 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:efe68302-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:efe6ab98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41921 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Glutathione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:efe6d4c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:efe6fe22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:efe726ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11168 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:efe74f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14576 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Unclassified (ELAV-like protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:efe777e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15717 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Unclassified (ELAV-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:efe7a2be-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:efe7ce92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:efe7fa5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19357 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:efe82374-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:efe84c78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFU5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Inositol polyphosphate multikinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:efe8750e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHH9 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Kinase (Inositol hexakisphosphate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:efe89da4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:3514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quercetin targets Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:efe8d652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:efe8d652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:efe8d652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:efe8d652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:efe8d652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:efe92382-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rasagiline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:efe94c2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rasagiline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:efe9781e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rasagiline targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:efe9a122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:efe9c9a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:3521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:efe9f244-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:3521 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:efea1b8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:efea4438-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.16']} DrugCentral uuid:efea6cc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:efea955a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:efeabe72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:efeae712-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:efeb0fb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:efeb396a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:3524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 resorcinol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:efeb6282-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:3524 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:efeb8f0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 revaprazan is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:efeb8f0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3525 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 revaprazan is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:efebbd36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:3529 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rioprostil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) DrugCentral uuid:efebe2de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:3531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:efec0b4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:3531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.46']} DrugCentral uuid:efec33ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.57']} DrugCentral uuid:efec67fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:efec67fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:efec67fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:efec67fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:efecb2e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WQX9 biolink:molecularly_interacts_with DrugCentral:3531 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roflumilast targets Enzyme (Phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:efecdb6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:efed0416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:efed2e5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:efed56f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:efed7f86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:efeda8d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:efedd152-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:efedf9e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:efee2396-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:efee4cae-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:efee753a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:efee9de4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05771 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C beta type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:efeec652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:efeef082-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:efef1904-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22694 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:efef41a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:efef6a26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:efef935c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05129 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C gamma type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:efefbbd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:efefe460-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:eff00ce2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:eff035e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:eff05e68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:eff086f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:eff0af9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:eff0dafa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:eff10476-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:eff12d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:eff1564c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:eff17ef6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:eff1a76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:eff1d004-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:eff1f8d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:eff22202-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:eff24a98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:eff2732e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:eff29c78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:eff2c522-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:eff2ed9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eff31644-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:eff33f8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:eff36810-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:eff3909c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:eff3b946-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:eff3e240-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:eff40bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:eff43484-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eff45dec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:eff48984-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:eff4b22e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JI10 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:eff4daa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:eff504b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:eff52d58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:eff555ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:eff57e84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:eff5a77e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:eff5d00a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:eff5f878-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:eff62104-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:eff64aa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:eff67348-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:eff69bde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:eff6c46a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:eff6ed96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:eff71636-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:eff73eb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:eff76758-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:eff7903e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:eff7b8de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:eff7e160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:eff80b0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:eff833d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:eff85c4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y243 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (RAC-gamma serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:eff884da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:eff8ae9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:eff8d732-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:eff900c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:eff92944-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:eff9522a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:eff97aca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:eff9a360-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:eff9cbec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:eff9f856-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:effa229a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:effa4b3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:effa73c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:effa9d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:effac5a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:effaee32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:effb1740-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:effb3fe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:effb6876-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:effb90f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:effbba88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:effbe30a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:effc0b8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:effc3422-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:effc5d6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:effc85f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:effcae8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:effcd80a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:effd012c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:effd29ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:effd523a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:effd7ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:effda668-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:effdd1c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:effdfd3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:effe26ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:effe4f50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:effe77dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76039 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase-like 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:effea072-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41743 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C iota type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:effec958-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:effef1da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60331 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:efff1a52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:efff4356-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:efff6dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:efff96ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:efffda3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:efffda3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:efffda3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:efffda3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:efffda3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:efffda3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:efffda3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:efffda3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:f00060c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f00060c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f00060c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f00060c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f000ab9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f000f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f000f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f000f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f000f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f000f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f000f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f000f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f000f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f000f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f000f69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f0017a54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3534 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rufinamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f001a5c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:f001cf0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.454']} DrugCentral uuid:f001f7ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:f002203a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f00248c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:f00271ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:f0029a38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:f002c2ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:f002eb6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02769 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:f00314c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:f0033d6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:f00366ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:f0038f6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZQ4 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets GPCR (Neuromedin-U receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f003b864-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03469 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:f003e21c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3535 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rutoside targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:f0040b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f0043384-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f0045ca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:f0048546-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:f004adc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sabcomeline is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f004e73e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f004e73e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f004e73e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f004e73e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f004e73e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f0053cc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:3542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saralasin is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:f0056556-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:3542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saralasin targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:f0058ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saralasin targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:f005b74a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:3542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saralasin is antagonist of GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f005e3aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saralasin targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f005e3aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saralasin targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f0061866-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:3548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitaxentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:f006411a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:3548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitaxentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f00669b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:3548 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sitaxentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:f0069232-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stallimycin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f006bc76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:3553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stallimycin targets Cytosolic other (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f006ed68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stallimycin targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f006ed68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3553 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stallimycin targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f007259e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:3557 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbentine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:f0074ed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:3557 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulbentine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:f007776a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:3574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulmazole targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:f007a3e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:3574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulmazole targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:f007a3e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:3574 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulmazole targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:f007d7e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxedrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:f00800e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZQ4 biolink:molecularly_interacts_with DrugCentral:3577 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxedrine targets GPCR (Neuromedin-U receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:f008296c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3579 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:f0084de8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:3580 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamibarotene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:f0087688-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:3580 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamibarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:f008a07c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:3580 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tamibarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f008c908-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:f008f1a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:f0091a52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:f00944d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:f0096d72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:f009961c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:f009bf48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:f009e810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:f00a10b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) DrugCentral uuid:f00a3518-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:f00a5eb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:f00a8748-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.09']} DrugCentral uuid:f00aaffc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:f00ad982-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:f00b02ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:f00b2b94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:3584 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 terazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:f00b5c18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f00b5c18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f00b5c18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f00ba34e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f00ba34e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f00ba34e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f00bf5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f00bf5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f00bf5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f00bf5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f00bf5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f00bf5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f00c6f4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:f00c6f4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:f00c6f4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:f00c6f4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:f00c6f4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:f00c6f4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:f00cc508-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:3601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiram targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:f00cee2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75936 biolink:molecularly_interacts_with DrugCentral:3601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiram targets Enzyme (Gamma-butyrobetaine dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f00d16ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99685 biolink:molecularly_interacts_with DrugCentral:3601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiram targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:f00d3f60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:3601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiram targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f00d6878-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:3601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiram targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:f00d9122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:3601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f00dbb98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:3601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:f00de438-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:3601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiram targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:f00e0dfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:3601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiram targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f00e369a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:3601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f00e5f30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:3604 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thyropropic acid targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.39']} DrugCentral uuid:f00e87c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:3604 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thyropropic acid targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.72']} DrugCentral uuid:f00eb110-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:3604 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thyropropic acid targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:f00ed992-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tioxolone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f00f0214-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tioxolone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:f00f2a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3607 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tioxolone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f00f539a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tipranavir targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:f00f77ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:3609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tipranavir targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:f00fa0b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:3609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tipranavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f00fc938-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80W54 biolink:molecularly_interacts_with DrugCentral:3609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tipranavir targets Enzyme (CAAX prenyl protease 1 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f00ff516-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14091 biolink:molecularly_interacts_with DrugCentral:3609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tipranavir targets Enzyme (Cathepsin E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:f0101df2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DJD9 biolink:molecularly_interacts_with DrugCentral:3609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tipranavir targets Enzyme (Pepsin A-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f010469c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:3611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiratricol targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:f0106f28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:3611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiratricol targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.39']} DrugCentral uuid:f010985e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiratricol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:f010c0cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:3611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiratricol targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.82']} DrugCentral uuid:f010e96c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:3611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiratricol targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:f011127a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:3611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiratricol targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:f0113b88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:3611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tiratricol targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:f0116400-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:3613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 Vitamin E targets Enzyme (Glutathione S-transferase P) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f0118c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49638 biolink:molecularly_interacts_with DrugCentral:3613 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 Vitamin E targets Transporter (Alpha-tocopherol transfer protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f011b6ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:3616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toliprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:f011df84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:3616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toliprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:f012081a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toliprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.36']} DrugCentral uuid:f01230ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:3616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 toliprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.75']} DrugCentral uuid:f0125a2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3617 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolnaftate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.894']} DrugCentral uuid:f01282cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3617 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolnaftate targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:f012ab4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:3617 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolnaftate targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:f012d3bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:f012fcca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramazoline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:f013254c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramazoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:f01355b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:f01355b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:f01355b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:f0139f9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0139f9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0139f9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f013dec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclocarban targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f014073c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P95276 biolink:molecularly_interacts_with DrugCentral:3630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase; Epoxide hydrolase EphB) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f0143072-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07099 biolink:molecularly_interacts_with DrugCentral:3630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f01458f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D379 biolink:molecularly_interacts_with DrugCentral:3630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f0148180-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f014aa20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16152 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Enzyme (Carbonyl reductase [NADPH] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:f014d31a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6GI75 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f014fbba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:f0152446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q965D5 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Enzyme (Enoyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.28']} DrugCentral uuid:f0154dae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54616 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f0157874-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6UCJ9 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Enzyme (Enoyl-acyl carrier reductase; Enoyl-acyl carrier reductase ENR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f015a114-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BJJ9 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Enzyme (Enoyl-ACP reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f015c98c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9RMI3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADPH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:f015f2cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0161b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:M9TGV3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NULLDH]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f0164416-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:3631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triclosan targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:f0166c84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:3639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f0169560-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15077 biolink:molecularly_interacts_with DrugCentral:3639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f016bde2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:3639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:f016e6c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:3639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f0170f36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:3639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 uridine triphosphate targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:f01739a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35811 biolink:molecularly_interacts_with DrugCentral:3639 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f0176238-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:3642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vildagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f0178ac4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:3642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vildagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f017b364-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:3642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vildagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:f017dcae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97321 biolink:molecularly_interacts_with DrugCentral:3642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vildagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:f0180544-ac81-11ec-8b6b-0242ac110002 UniProtKB:E1BI31 biolink:molecularly_interacts_with DrugCentral:3642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vildagliptin targets Unclassified (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f0182dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:3642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vildagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f018568e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:3642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vildagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f0187f92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3643 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f018a81e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3643 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f018d0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3643 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f018f936-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3643 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:f019431e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f019431e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f019431e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f019431e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f019431e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f019431e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f019431e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f019431e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f019431e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f019b92a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3651 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.86']} DrugCentral uuid:f019e18e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:f01a0a1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:f01a32ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:f01a5ba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f01a8454-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f01aace0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:f01ad684-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:f01aff4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f01b27e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:f01b506e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f01b79ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f01ba230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f01bcaa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f01bf334-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f01c1c1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:f01c449c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f01c6d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:f01c95b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f01cc20a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f01ceadc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f01d1368-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f01d4ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:f01d4ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:f01d4ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:f01d4ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:f01d4ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:f01da242-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f01dcad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:f01df4e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f01e1d94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:f01e4634-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f01e76ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:f01e76ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:f01e76ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:f01ebed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f01ebed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f01ebed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f01f1122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:f01f1122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:f01f1122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:f01f1122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:f01f1122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:f01f1122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:f01f73d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3658 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 xylometazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:f01f9c6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.163']} DrugCentral uuid:f01fc572-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:f01fee08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f02016b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:f0203f3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.106']} DrugCentral uuid:f0206928-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f02091b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f020ba54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f020e2cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:f0210c0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:f02134c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f0215d7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f0218614-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.692']} DrugCentral uuid:f021aee6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:f021d772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f0220012-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:f0222984-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f0225224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:f0227aba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:f022a364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f022cc5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.182']} DrugCentral uuid:f022f4ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:f0231e98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f0234738-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:f0237122-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:f02399b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:f023c230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:f023eada-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f02416d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:f0243f76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:f0246820-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:f02490c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:f024ba00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:f024ea52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f024ea52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f024ea52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f02539bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f02539bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f02539bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f02539bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f02539bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f0259786-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:f0259786-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:f0259786-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:f025e006-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f025e006-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f025e006-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f0261f12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:f0264794-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f02671e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:f0269a82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:3659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:f026c322-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3680 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azacyclonol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f026f37e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f026f37e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f026f37e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f0273316-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:f0275bc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:f027847e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:f027aeae-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3686 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f027dad2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3689 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bropirimine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f0280354-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:3707 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chlorthenoxazine targets Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:f0282c08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ciramadol is modulator of GPCR (Mu-type opioid receptor) DrugCentral uuid:f02850f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:3715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobenztropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f028816c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f028816c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f028816c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f028c884-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f028c884-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f028c884-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f0290858-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3787 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 myrtecaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.316']} DrugCentral uuid:f02938be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:f02938be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:f02938be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:f0297e5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3839 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tasosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:f0297e5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3839 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tasosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:f029b424-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:3839 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tasosartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:f029dd32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:f02a05aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:3848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f02a2eea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:3848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f02a5762-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:f02a7fee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:3848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velnacrine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:f02aa870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:3851 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f02ad17e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3851 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:f02afa1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:3851 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexibuprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:f02b22dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:3851 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexibuprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:f02b4c12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:3851 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:f02b77be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3851 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f02ba07c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f02bc912-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f02bf23e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f02c1ade-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f02c4360-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:f02c6be2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f02c94d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f02cbd4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f02ce5e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:f02d0f98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f02d3bb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f02d64e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:f02d8d74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11416 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:f02db600-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:f02ddf36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22605 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:f02e07d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18911 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f02e306c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05343 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f02e595c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22736 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Nuclear other (Nuclear receptor subfamily 4 group A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f02e8210-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:f02eaaa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13133 biolink:molecularly_interacts_with DrugCentral:3862 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alitretinoin targets Nuclear other (Oxysterols receptor LXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f02ed314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:3871 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 artemisinin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:f02efd6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzamycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:f02f268e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:3875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzamycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:f02f4f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:3875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzamycin targets GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:f02f7788-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:3875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzamycin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:f02fa0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:3875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzamycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:f02fc94a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:3880 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.843']} DrugCentral uuid:f02ff5d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:3880 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:f02ff5d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:3880 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:f03035d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:f03035d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:f03035d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:f03035d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:f0308010-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biriperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f030a892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biriperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:f030d358-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biriperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:f030fec8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:3883 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 biriperone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:f0312902-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3911 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobetasone butyrate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:f0314d60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:f03176b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:f0319f40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.665']} DrugCentral uuid:f031c7c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.372']} DrugCentral uuid:f031f06c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:f032195c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:f03241e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:f0326a6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:f03292e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:f032bfc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f032eb34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:f03313ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:f0333d28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:f03365d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:f0338e72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.25']} DrugCentral uuid:f033c676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f033c676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f033c676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f033c676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f033c676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f0342440-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:f0342440-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:f0342440-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:f0346c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:f0346c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:f0346c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:f034b04a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:3912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clorotepine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:f034d8ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f035016c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:3920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:f0352b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f03553e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f0357c64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone phosphate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.79']} DrugCentral uuid:f035a518-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:3920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone phosphate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:f035ce26-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone phosphate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f035f6d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:3920 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexamethasone phosphate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:f0361f52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:f036487e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f036715a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f03699e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f036c25e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f036eb9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0371434-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:f0373cac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.57']} DrugCentral uuid:f0376556-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:f0378e78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f037b83a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f037e0a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:f0380a38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f0383382-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 androstanolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f0385c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dolasetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.226']} DrugCentral uuid:f03884b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dolasetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.698']} DrugCentral uuid:f038ad62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:3944 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etoposide phosphate is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:f038d27e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:f038fb14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.928']} DrugCentral uuid:f03923a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:f0394c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.208']} DrugCentral uuid:f0397576-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.971']} DrugCentral uuid:f0399e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:f039c6f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.793']} DrugCentral uuid:f039ef92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.801']} DrugCentral uuid:f03a1940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.748']} DrugCentral uuid:f03a41cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:f03a6a30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:f03a941a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:f03abca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.122']} DrugCentral uuid:f03ae53c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f03b0da0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f03b3e38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f03b3e38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f03b3e38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f03b7d8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3959 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone butyrate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:f03ba5ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ilaprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:f03ba5ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ilaprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:f03bd71c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:f03c0016-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f03c28ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f03c512e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.407']} DrugCentral uuid:f03c7a50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.125']} DrugCentral uuid:f03ca2d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.924']} DrugCentral uuid:f03ccb68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.891']} DrugCentral uuid:f03cf3ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.586']} DrugCentral uuid:f03d1cf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.244']} DrugCentral uuid:f03d458e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.451']} DrugCentral uuid:f03d6f32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.539']} DrugCentral uuid:f03d97d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin is allosteric modulator of Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f03dc41e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f03df8f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f03df8f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f03df8f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f03df8f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f03e4394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P91730 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin is modulator of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:f03e6810-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q25634 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin is modulator of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:f03e8c5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11507 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets Enzyme (Sarcoplasmic/endoplasmic reticulum calcium ATPase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f03eb4fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06685 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets Enzyme (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f03eddd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q64578 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin targets Enzyme (Sarcoplasmic/endoplasmic reticulum calcium ATPase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:f03f0676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:3972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivermectin is allosteric modulator of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f03f2eda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29029 biolink:molecularly_interacts_with DrugCentral:3976 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kinetin targets Enzyme (Endochitinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f03f5752-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:3977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kojic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:f03f8286-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kojic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.65']} DrugCentral uuid:f03fab12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:3977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kojic acid targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f03fd38a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00371 biolink:molecularly_interacts_with DrugCentral:3977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kojic acid targets Unclassified (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:f03ffc20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11344 biolink:molecularly_interacts_with DrugCentral:3977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kojic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:f0402560-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:3977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kojic acid targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:f0404e00-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2ZB02 biolink:molecularly_interacts_with DrugCentral:3977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kojic acid targets Unclassified (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:f0407772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:3977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kojic acid targets Unclassified (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:f040a04e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00024 biolink:molecularly_interacts_with DrugCentral:3977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 kojic acid targets Enzyme (Polyphenol oxidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:f040c934-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75936 biolink:molecularly_interacts_with DrugCentral:3995 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 meldonium targets Enzyme (Gamma-butyrobetaine dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f040f1e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:3998 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octanoic acid targets GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:f0411a88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:3998 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 octanoic acid targets GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:f041433c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4002 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niperotidine is antagonist of GPCR (Histamine H2 receptor) DrugCentral uuid:f041698e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mozavaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:f0419238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:4004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mozavaptan is antagonist of GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f041bad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:4004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mozavaptan targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f041e440-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:4004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mozavaptan targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f0420ca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:4004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mozavaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f0423922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:4004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mozavaptan targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f0423922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:4004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mozavaptan targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f0426d16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:4004 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mozavaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:f0429624-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:f042beb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f042e872-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f04310ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:f0433c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:f04364b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14832 biolink:molecularly_interacts_with DrugCentral:4050 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spaglumic acid is agonist of GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f0438e3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:f043b77a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48147 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Enzyme (Prolyl endopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:f043dff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f0444208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f04518cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4055 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baicalin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:f04541e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4061 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 timolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:f0456aac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4061 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 timolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f04593ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4061 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 timolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.81']} DrugCentral uuid:f045bcaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4061 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 timolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f045e540-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4061 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 timolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f0460ee4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4061 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 timolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.78']} DrugCentral uuid:f04637fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:4061 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 timolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.44']} DrugCentral uuid:f04660b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.807']} DrugCentral uuid:f0468964-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.243']} DrugCentral uuid:f046b29a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.929']} DrugCentral uuid:f046dd9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.425']} DrugCentral uuid:f047063c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.857']} DrugCentral uuid:f0472ee6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:f0475768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:f04781c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.802']} DrugCentral uuid:f047aa6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.952']} DrugCentral uuid:f047d30a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.789']} DrugCentral uuid:f047fbfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirilazad targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:f0482486-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4072 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ascorbic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:f0484d12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13674 biolink:molecularly_interacts_with DrugCentral:4072 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ascorbic acid targets Enzyme (Prolyl 4-hydroxylase subunit alpha-1) DrugCentral uuid:f0487166-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02809 biolink:molecularly_interacts_with DrugCentral:4072 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ascorbic acid targets Enzyme (Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1) DrugCentral uuid:f04895ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UGH3 biolink:molecularly_interacts_with DrugCentral:4072 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ascorbic acid targets Transporter (Solute carrier family 23 member 2) DrugCentral uuid:f048baf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHI7 biolink:molecularly_interacts_with DrugCentral:4072 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ascorbic acid targets Transporter (Solute carrier family 23 member 1) DrugCentral uuid:f048df52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00689 biolink:molecularly_interacts_with DrugCentral:4072 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ascorbic acid targets Enzyme (Pancreatic alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:f04907de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:4074 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minodronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f0493060-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:4074 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minodronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f04959a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22939 biolink:molecularly_interacts_with DrugCentral:4074 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minodronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0498204-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12051 biolink:molecularly_interacts_with DrugCentral:4074 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 minodronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f049aea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4099 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamlodipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:f049aea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4099 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levamlodipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:f049dd4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DJD9 biolink:molecularly_interacts_with DrugCentral:4106 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sucralfate is inhibitor of Enzyme (Pepsin A-5) DrugCentral uuid:f04a01c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol is agonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:f04a2b46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.99']} DrugCentral uuid:f04a53be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f04a7d76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol is allosteric modulator of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f04aa5ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:f04ace7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol is allosteric modulator of Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f04af706-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f04b2032-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:f04b4896-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:f04b712c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:f04b99d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f04bc2d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f04bef4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:f04bef4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:f04c273e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QZN9 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:f04c273e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QZN9 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:f04c5e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:4109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronabinol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f04c872e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:f04cafc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:4110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:f04cd878-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:4110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:f04d0262-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:4110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:f04d3020-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:4111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 besifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:f04d3020-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:4111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 besifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:f04d6266-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:4111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 besifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:f04d6266-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:4111 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 besifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:f04d9146-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:4112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronedarone targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.229']} DrugCentral uuid:f04db9d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronedarone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:f04de344-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:4112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronedarone targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:f04e0be4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronedarone is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f04e36e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronedarone targets Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:f04e5f68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:4112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronedarone targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.229']} DrugCentral uuid:f04e87fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60741 biolink:molecularly_interacts_with DrugCentral:4112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) DrugCentral uuid:f04eac7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL51 biolink:molecularly_interacts_with DrugCentral:4112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) DrugCentral uuid:f04ed1a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P1Z3 biolink:molecularly_interacts_with DrugCentral:4112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3) DrugCentral uuid:f04ef61c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:4112 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) DrugCentral uuid:f04f1aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:4113 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prasugrel is antagonist of GPCR (P2Y purinoceptor 12) DrugCentral uuid:f04f3eec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saxagliptin targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:f04f63c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saxagliptin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:f04f8852-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saxagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f04fb0de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saxagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f04fd97e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4114 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saxagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f0500372-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:f0502bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:f050549e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f0507d3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.75']} DrugCentral uuid:f050a674-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.187']} DrugCentral uuid:f050cf00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:f050f7aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.61']} DrugCentral uuid:f0512068-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:f0514958-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.93']} DrugCentral uuid:f05171ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f0519a8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.47']} DrugCentral uuid:f051c446-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:f051f04c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.73']} DrugCentral uuid:f05218d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:f052416e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.644']} DrugCentral uuid:f0526a90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:f0529330-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:f052bd06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.107']} DrugCentral uuid:f052e57e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.039']} DrugCentral uuid:f0530ef0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.491']} DrugCentral uuid:f0533772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.565']} DrugCentral uuid:f0536008-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:f05388a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:f053b328-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:f053dbb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.504']} DrugCentral uuid:f0540436-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:f0542cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:f05456ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:f0547f4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:f054a7ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:4115 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asenapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:f054d104-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4117 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralatrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:f054f9ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:4117 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralatrexate targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:f055223a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:4117 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralatrexate targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:f0554ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:4117 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralatrexate targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:f05574ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:f055a016-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:f055ca82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f055f408-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f0561d5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.74']} DrugCentral uuid:f05645fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f0566ea6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0569732-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f056c040-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f056e8cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f057116c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:f05739ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:f0576586-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f0578e3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f057b702-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f057e074-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:f0580932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.1']} DrugCentral uuid:f05831e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.31']} DrugCentral uuid:f0585a9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f058838a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f058ac3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f058d600-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f058fea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f05929a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f059524c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f0597af6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f059a396-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f059cce0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f059f684-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f05a1efc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f05a4800-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:f05a70d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f05a9972-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f05ac212-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:f05aeba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f05b162c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f05b3ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f05b6726-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f05b9052-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f05bb8de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f05be250-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f05c0afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:f05c33f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f05c5c76-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:f05c84ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f05cad5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f05cd8a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:f05d01f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f05d2a98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f05d532e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f05d7c6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f05da518-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f05dcd90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f05df7a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f05e2038-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f05e48b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:f05e713c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f05e9b44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib is inhibitor of Kinase (Tyrosine-protein kinase ITK/TSK) DrugCentral uuid:f05ec18c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f05eeb44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:f05f13ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f05f3d38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:f05f65c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f05f8e50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f05fb6e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f05fdfe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f060086c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f06030f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f060598e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:f060847c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f060acfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f060d58a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f060fe20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f06127ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f0615078-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f061790e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f061a1f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f061ca80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21127 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 11B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f061f410-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ88 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0621c9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f06246c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f0627214-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:f0629aa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6P3R8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase Nek5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f062c340-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f062ec80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f063150c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f0633d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f0636624-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f0638f1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f063b7c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f063e068-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f06408ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:f064345a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:f0645ce6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f0648572-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f064aeb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f064d752-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:f065010a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:f06529aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f0655290-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f0657b1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f065a3bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60331 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f065cd42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f065f7cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f06622f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:f0664b78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:4118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pazopanib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f066747c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:f0669dd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.328']} DrugCentral uuid:f066c666-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f066eed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.604']} DrugCentral uuid:f0671774-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.523']} DrugCentral uuid:f0674082-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:f0676922-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:f06791c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.292']} DrugCentral uuid:f067bb0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f067e398-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:f0681098-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:f0681098-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:f068486a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:f068486a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:f0687d1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z2V5 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f068cc04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0696754-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14833 biolink:molecularly_interacts_with DrugCentral:4120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f06990c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14831 biolink:molecularly_interacts_with DrugCentral:4120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:f069bb5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15303 biolink:molecularly_interacts_with DrugCentral:4120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f069e4f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00222 biolink:molecularly_interacts_with DrugCentral:4120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:f06a0d6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31423 biolink:molecularly_interacts_with DrugCentral:4120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f06a3670-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35349 biolink:molecularly_interacts_with DrugCentral:4120 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f06a5f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 auranofin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f06a879c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 auranofin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f06ab03c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 auranofin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:f06ad922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 auranofin targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:f06b01ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 auranofin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f06b2a1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 auranofin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.405']} DrugCentral uuid:f06b5294-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 auranofin targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:f06b7800-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 auranofin targets Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:f06b9c72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 auranofin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.922']} DrugCentral uuid:f06bc4d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4122 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 auranofin is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f06bed4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51788 biolink:molecularly_interacts_with DrugCentral:4123 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lubiprostone is opener of Ion channel (Chloride channel protein 2) DrugCentral uuid:f06c1242-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:f06c3ad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f06c6378-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:f06c8c22-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f06cb63e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:f06cded4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f06d0760-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:f06d2fe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f06d5b2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:f06d83de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f06dac4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f06dd5aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q94F81 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (HD2 type histone deacetylase HDA106; Histone deacetylase 2b; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f06dfe22-ac81-11ec-8b6b-0242ac110002 UniProtKB:O09106 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:f06e2690-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ZTP8 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:f06e4efe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:f06e7866-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q70I53 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase-like amidohydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f06ea0de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f06ec974-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7K6A1 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f06ef1e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f06f1b40-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06f47b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f06f47b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f06f7f9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f06f7f9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f06fdba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f0708296-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f0708296-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f0708296-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f0708296-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f070d0de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase (HDAC1 and HDAC2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f070d0de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase (HDAC1 and HDAC2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f0711ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:f0711ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:f0711ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:f0711ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:f0711ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:f0711ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:f0711ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:f0718c22-ac81-11ec-8b6b-0242ac110002 UniProtKB:A5H660 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Unclassified (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f071b4cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24527 biolink:molecularly_interacts_with DrugCentral:4124 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorinostat targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f071dd58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:4125 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proline targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:f07205ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:4125 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 proline targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:f0722f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:4126 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asparagine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:f0725774-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4127 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 serine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f0727fd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:4127 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 serine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f072a954-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07314 biolink:molecularly_interacts_with DrugCentral:4127 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 serine targets Enzyme (Gamma-glutamyltranspeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:f072d2c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63116 biolink:molecularly_interacts_with DrugCentral:4127 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 serine targets Unclassified (Asc-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:f072fb52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:4127 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 serine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:f07323e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:4128 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:f0734c92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:4134 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyridoxal targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f07375a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4135 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisdexamfetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:f0739b34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4135 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisdexamfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:f073bf9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:4135 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lisdexamfetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:f073e3e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:f0740d12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:f07435bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:f0745eca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.925']} DrugCentral uuid:f0748774-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f074b2c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f074db5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:f07503de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.209']} DrugCentral uuid:f0752cec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:f075556e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.617']} DrugCentral uuid:f0757e0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.569']} DrugCentral uuid:f075a69a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:f075cfd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.635']} DrugCentral uuid:f075f852-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:f07620fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:f0764974-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.251']} DrugCentral uuid:f0767430-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.916']} DrugCentral uuid:f0769fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.061']} DrugCentral uuid:f076cc5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:f076f7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:f07720e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.195']} DrugCentral uuid:f0774964-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.265']} DrugCentral uuid:f07771fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:f0779b44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.556']} DrugCentral uuid:f077c3e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:f077ec7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:f0781524-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:f0783f5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:f0786844-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:f07890e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.809']} DrugCentral uuid:f078b984-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.975']} DrugCentral uuid:f078e26a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:f0790af6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:f0793396-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f0795c2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.124']} DrugCentral uuid:f07986a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.241']} DrugCentral uuid:f079af4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f079d7d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.945']} DrugCentral uuid:f07a0078-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:f07a2bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.294']} DrugCentral uuid:f07a5460-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.037']} DrugCentral uuid:f07a7d00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:f07aa618-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.416']} DrugCentral uuid:f07ad2b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:f07afb5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f07b23f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.084']} DrugCentral uuid:f07b4ce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.628']} DrugCentral uuid:f07b7610-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.012']} DrugCentral uuid:f07b9ec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f07bc746-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.233']} DrugCentral uuid:f07bf1d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.325']} DrugCentral uuid:f07c1c78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:f07c44e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:f07c6d86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f07c96d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4138 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentian violet targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.701']} DrugCentral uuid:f07cbf7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4141 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 udenafil targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:f07ce3f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:4141 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 udenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.084']} DrugCentral uuid:f07d0c8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:4142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadiazine silver is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:f07d3176-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfadiazine silver targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:f07d59ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darunavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:f07d8298-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:4143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darunavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.658']} DrugCentral uuid:f07dab56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:4143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darunavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.85']} DrugCentral uuid:f07dd78e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:4143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darunavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.21']} DrugCentral uuid:f07e025e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:4143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darunavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.96']} DrugCentral uuid:f07e2b12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darunavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:f07e5470-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:4143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darunavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:f07e7d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium lauryl sulfate targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:f07ea5a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium lauryl sulfate targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:f07ece46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone propionate is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:f07ef876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:4146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone propionate targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:f07f2116-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4146 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone propionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f07f60d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f07f60d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f07f60d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f07f60d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f07f60d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f07f60d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f07f60d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f07fc72e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimonabant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f07fefc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimonabant targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:f0801850-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:f0804172-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:4150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimonabant targets GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f08069f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:4150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:f08092a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:4150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f080bbd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f080e4ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:4150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimonabant targets GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f0810d50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:4150 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimonabant is antagonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:f08135dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4151 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silodosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:f0815fc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4151 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silodosin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:f081865e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4151 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silodosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.44']} DrugCentral uuid:f081aef4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4151 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silodosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f081d794-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4151 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silodosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f0820098-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4151 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 silodosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:f082292e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2VKV7 biolink:molecularly_interacts_with DrugCentral:4152 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 permethrin is blocker of Ion channel (Sodium channel protein) DrugCentral uuid:f0826c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f0826c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f0826c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f0826c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f0826c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f0826c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f0826c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f0826c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f0826c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f082e12a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P39654 biolink:molecularly_interacts_with DrugCentral:4156 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edaravone targets Enzyme (Polyunsaturated fatty acid lipoxygenase ALOX15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:f0830dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4157 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lercanidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:f0830dbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4157 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lercanidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:f0833d3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4161 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 temsirolimus targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:f08361b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:4161 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 temsirolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) DrugCentral uuid:f0838616-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:4161 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 temsirolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f083aeac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00688 biolink:molecularly_interacts_with DrugCentral:4161 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 temsirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP3) DrugCentral uuid:f083d88c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexlansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:f083d88c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexlansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:f08406fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:4162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexlansoprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:f0842f8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:4162 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexlansoprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f084ee34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f086da50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:f0870304-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22462 biolink:molecularly_interacts_with DrugCentral:4163 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fampridine is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:f0872b86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 liraglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.2']} DrugCentral uuid:f08753fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4165 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alcaftadine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:f08778de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4166 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ulipristal is antagonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f087a1e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95470 biolink:molecularly_interacts_with DrugCentral:4167 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fingolimod targets Enzyme (Sphingosine-1-phosphate lyase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:f087ca82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:4167 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f087f304-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:4167 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f0881bea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:4167 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f0884476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:4167 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f0886cee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923J1 biolink:molecularly_interacts_with DrugCentral:4167 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fingolimod is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f0889584-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lurasidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:f088c02c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lurasidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.195']} DrugCentral uuid:f088ebf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.305']} DrugCentral uuid:f0891770-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lurasidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.967']} DrugCentral uuid:f0893ff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lurasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f08968f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lurasidone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:f0899178-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.69']} DrugCentral uuid:f089ba2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lurasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.003']} DrugCentral uuid:f089e3bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4168 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.328']} DrugCentral uuid:f08a23d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f08a23d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f08a23d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f08a23d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f08a23d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f08a23d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f08a23d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f08a8466-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:4170 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tesamorelin is agonist of GPCR (Growth hormone-releasing hormone receptor) DrugCentral uuid:f08ac962-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:f08ac962-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:f08ac962-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:f08ac962-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:f08ac962-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:f08ac962-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:f08ac962-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:f08ac962-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:f08ac962-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:f08b4e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:f08b76f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f08b9f86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f08bc862-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:f08bf0ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir is inhibitor of Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f08c195c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60911 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir targets Enzyme (Cathepsin L2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:f08c41e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43235 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir targets Enzyme (Cathepsin K) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f08c6c54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f08c94ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBX1 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir targets Enzyme (Cathepsin F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f08cc262-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:f08cc262-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:f08cf6b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4172 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 boceprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f08d1f3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:f08d47be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f08d7040-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNI1 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Enzyme (Chymotrypsin-like elastase family member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f08d9926-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f08dc19e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:f08dea2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:f08e12b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir is inhibitor of Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f08e3da4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60911 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Enzyme (Cathepsin L2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:f08e6680-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43235 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Enzyme (Cathepsin K) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:f08e8f84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f08ebc16-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) DrugCentral uuid:f08ebc16-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) DrugCentral uuid:f08eeb00-ac81-11ec-8b6b-0242ac110002 UniProtKB:C1KIQ2 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f08f1382-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0ZMF1 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:f08f3c22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q91RS4 biolink:molecularly_interacts_with DrugCentral:4173 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:f08f6526-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilpivirine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f08f8dd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:4174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilpivirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:f08fb242-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:4174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilpivirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f08fdac4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilpivirine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f09005e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:4174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilpivirine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:f0902ec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linagliptin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:f090574c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:f0907fec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:4175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:f090a9a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:f090d23a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97321 biolink:molecularly_interacts_with DrugCentral:4175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f090fab2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:4175 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f091233e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f0914c10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abiraterone acetate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:f09174a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:4176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abiraterone acetate is inhibitor of Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:f0919d32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:4176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:f091c5d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:4176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:f091f160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11715 biolink:molecularly_interacts_with DrugCentral:4176 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 17A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:f0921bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:4177 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin enacarbil is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) DrugCentral uuid:f0924070-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:4177 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gabapentin enacarbil is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) DrugCentral uuid:f09264d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f0928dd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:f092b65e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:f092def4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:f093079e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:f09330ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f0935956-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f09381d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f093ab90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f093d430-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f093fcbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f09425f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f0944ee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f09477a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f094a13a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f094c9c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f094f2ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f0951b60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f09543f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f0956c8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f0959702-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f095bfac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:f095e950-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f09611dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f0963ae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0966376-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:f0968c16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f096b484-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f096dd92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f097060a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f0972e96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f097586c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:f09780ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f097a970-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f097d206-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:f097faec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f0982396-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f0984c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f09874b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f0989e8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f098c724-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f098efba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f099183c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f0994276-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f0996b02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f0999384-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f099bc1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f099e50a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:f09a0daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.34']} DrugCentral uuid:f09a3636-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f09a5ed6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f09a87bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:f09ab0d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f09ad96a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f09b0368-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f09b2ee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f09b57be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f09b8040-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f09ba962-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f09bd324-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:f09bfbd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f09c245a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f09c4d2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f09c75cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:f09c9f3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f09cc7ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f09cf272-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f09d1ae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:f09d436c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f09d6be4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f09d94d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f09dbd6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:f09de5ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f09e0ec8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f09e3768-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:f09e5fea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:f09e8880-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f09eb2a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:f09edce0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:f09f056c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f09f2e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:f09f56de-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f09f7f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f09fa7e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5VT25 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f09fd06e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f09ff954-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f0a021e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f0a04a62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f0a072e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f0a09fda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f0a0c884-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f0a0f106-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:f0a11a14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f0a142a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f0a16bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f0a19444-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f0a1bd20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f0a1e6c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:f0a20f5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:f0a237dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f0a26202-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0a28a8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:f0a2b31a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:f0a2db9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f0a30496-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:f0a32cfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f0a355a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f0a37e12-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f0a3a70c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f0a3cf98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4178 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:f0a403d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:f0a403d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:f0a403d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:f0a403d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:f0a4490a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f0a472ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:4181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:f0a49b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f0a4c434-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f0a4ecb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z351 biolink:molecularly_interacts_with DrugCentral:4181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 retigabine targets Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0a51542-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivaroxaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:f0a53dce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:4182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivaroxaban targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f0a56696-ac81-11ec-8b6b-0242ac110002 UniProtKB:O19045 biolink:molecularly_interacts_with DrugCentral:4182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rivaroxaban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:f0a58f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indacaterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:f0a5b7d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indacaterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f0a5e076-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indacaterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:f0a60aec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indacaterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:f0a63364-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 indacaterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:f0a65c04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:4184 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticagrelor is negative allosteric modulator of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f0a68472-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:4184 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticagrelor is inhibitor of Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f0a6ad62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EPX4 biolink:molecularly_interacts_with DrugCentral:4184 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ticagrelor targets GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f0a6d5c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4185 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vemurafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:f0a6fe66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4185 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vemurafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:f0a726f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4185 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vemurafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f0a74fec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4185 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vemurafenib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:f0a77986-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:4185 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vemurafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f0a7a280-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:4185 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vemurafenib targets Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:f0a7cb02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22830 biolink:molecularly_interacts_with DrugCentral:4185 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vemurafenib targets Enzyme (Ferrochelatase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f0a7f514-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:4185 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vemurafenib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f0a81dc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:4186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 icatibant is antagonist of GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:f0a84686-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25023 biolink:molecularly_interacts_with DrugCentral:4186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 icatibant targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.11']} DrugCentral uuid:f0a87084-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70526 biolink:molecularly_interacts_with DrugCentral:4186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 icatibant targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.96']} DrugCentral uuid:f0a89910-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46663 biolink:molecularly_interacts_with DrugCentral:4186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 icatibant is antagonist of GPCR (B1 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:f0a8c188-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32299 biolink:molecularly_interacts_with DrugCentral:4186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 icatibant is antagonist of GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:f0a8ea0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97583 biolink:molecularly_interacts_with DrugCentral:4186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 icatibant is antagonist of GPCR (B1 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f0a912dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f0a93b68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:f0a963d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:f0a98c6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f0a9b75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f0a9e018-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f0aa087c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f0aa3108-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:f0aa5a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0aa82c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f0aaab56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f0aad3e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0aafcc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f0ab255e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f0ab4dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:f0ab769e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f0ab9fe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f0abc892-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f0abf128-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:f0ac1a90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f0ac4312-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:f0ac6c98-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f0ac9538-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f0acbe3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f0ace6dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f0ad0f5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f0ad37f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f0ad62b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.26']} DrugCentral uuid:f0ad8f56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:f0adbac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f0ade3e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:f0ae0d3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f0ae3640-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.36']} DrugCentral uuid:f0ae5ecc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f0ae87d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:f0aeb070-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f0aed8f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:f0af0174-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0af2b18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f0af53b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:f0af7c44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f0afa4bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f0afce24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.13']} DrugCentral uuid:f0aff69c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:f0b01f14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:f0b047aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f0b07176-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f0b09a16-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f0b0c284-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f0b0eb1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f0b116ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f0b14240-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f0b16ad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:f0b19434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f0b1bcca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:f0b1e57e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f0b20e00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f0b23704-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:f0b25f90-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:f0b28826-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f0b2b09e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f0b2daba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:f0b3031e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:f0b32bb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:f0b35436-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f0b37e8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f0b3a710-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0b3cfba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f0b3f846-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0b42140-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f0b449cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:f0b47348-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f0b49bca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f0b4c5f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f0b4eeea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f0b51794-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f0b540b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:f0b56938-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f0b591c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:f0b5ba50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:f0b5e340-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f0b60bc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f0b6343a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f0b65cc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:f0b68656-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:f0b6aeec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f0b6d76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f0b7000e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f0b72926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f0b751bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:f0b77a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f0b7a2d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f0b7cc3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:f0b7f4be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:f0b81d40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:f0b845cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f0b87042-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:f0b898e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21127 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 11B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f0b8c16e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ88 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:f0b8eacc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f0b9136c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f0b93bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f0b96484-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TD19 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase Nek9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f0b98e96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0b9b740-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f0b9dfd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0ba0858-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f0ba3288-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:f0ba5b1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:f0ba83b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0baac54-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f0bad580-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f0bafe02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:f0bb2684-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:f0bb4f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f0bb7828-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f0bba0a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:f0bbc9a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f0bbf2da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f0bc1d82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f0bc4618-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:f0bc6f80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f0bc98ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f0bcc14c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:f0bce9ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f0bd1278-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f0bd3b72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f0bd63fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f0bd8c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:f0bdb520-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f0bddf64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0be07fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f0be309a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0be5926-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f0be8270-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f0beab06-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:f0bed37e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f0befc14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f0bf24fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f0bf4d9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f0bf7748-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0bfa0e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f0bfc982-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62190 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f0bff204-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02858 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f0c01a7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0c044ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f0c06d38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f0c095ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f0c0be50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f0c0eb32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:f0c0eb32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:f0c11f8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15357 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Enzyme (Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:f0c1480c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f0c17142-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NB16 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Mixed lineage kinase domain-like protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f0c19cc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4187 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f0c1c53e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:4188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deferiprone targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f0c1ee42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyprogesterone caproate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:f0c21778-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyprogesterone caproate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.261']} DrugCentral uuid:f0c23ff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyprogesterone caproate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.573']} DrugCentral uuid:f0c2687c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:4189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyprogesterone caproate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:f0c2911c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:4189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyprogesterone caproate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f0c2ba0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyprogesterone caproate targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.501']} DrugCentral uuid:f0c2e27a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyprogesterone caproate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:f0c30ae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyprogesterone caproate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:f0c33388-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4189 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydroxyprogesterone caproate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.664']} DrugCentral uuid:f0c35e3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f0c388a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0c3b128-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f0c3d9b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f0c403ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f0c42c66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0c454fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f0c47dc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:f0c4a664-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f0c4cee6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f0c4f74a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:f0c52134-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:f0c54e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:f0c578be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f0c5a140-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:f0c5ca62-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f0c5f302-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.44']} DrugCentral uuid:f0c61b8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:f0c6441a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:f0c66d1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f0c695a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f0c6be2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f0c6e6b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f0c71192-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:f0c73a14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f0c762a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:f0c78bb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:f0c7b44e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f0c7ddb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f0c806ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:f0c82fb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f0c85840-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:f0c880c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f0c8a944-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f0c8d2a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f0c8fb42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f0c923b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:f0c94c46-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f0c97536-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f0c99df4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f0c9c680-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f0c9ef2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f0ca1810-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f0ca40b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f0ca693c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f0ca91dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f0cabe14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f0cae6b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f0cb0f2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f0cb383a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f0cb61e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f0cb8a74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:f0cbb300-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f0cbdcea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f0cc056c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f0cc2e16-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f0cc568e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f0cc81c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f0ccaaa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0ccd33e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f0ccfbc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f0cd24ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f0cd4d46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:f0cd75d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f0cd9e72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f0cdc776-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f0cdeff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:f0ce1870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:f0ce41d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f0ce6d84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0ce9606-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:f0cebf28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f0cee804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f0cf1086-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:f0cf3908-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f0cf61a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f0cf8aa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:f0cfb342-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:f0cfdca0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f0d0054a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f0d0307e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f0d05928-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f0d081b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f0d0aa4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f0d0d326-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f0d0fbbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f0d12452-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f0d14e14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f0d176fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f0d19fa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:f0d1c812-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0d1f24c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0d21e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f0d248c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:f0d27140-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f0d29a58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f0d2c2bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f0d2eb5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0d313d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f0d33cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f0d36550-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f0d38ddc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0d3b776-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f0d3e3ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f0d40f14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f0d437aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f0d4609a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f0d4891c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0d4b194-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0d4da2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f0d5031a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f0d52bb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f0d554aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f0d57d40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f0d5a7c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0d5d06a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f0d5f8ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0d62178-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0d64a72-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f0d672fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f0d69b76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:f0d6c420-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:f0d6ed1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:f0d7159c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f0d7421a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:f0d7421a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:f0d77d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:f0d77d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:f0d7bb32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:f0d7bb32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:f0d7fab6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:f0d7fab6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:f0d7fab6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:f0d83e5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f0d83e5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f0d87248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:f0d89ae8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:f0d8c400-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:f0d8ec82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ruxolitinib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f0d9150e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.393']} DrugCentral uuid:f0d93e8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fesoterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.401']} DrugCentral uuid:f0d967a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fesoterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.271']} DrugCentral uuid:f0d99038-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.187']} DrugCentral uuid:f0d9b8ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4191 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:f0d9e1fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:4192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tafamidis is inhibitor of Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.936']} DrugCentral uuid:f0da0a90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:4192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tafamidis is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:f0da331c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:4192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tafamidis is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.627']} DrugCentral uuid:f0da5bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:4192 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tafamidis is binding agent of Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.812']} DrugCentral uuid:f0da84b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99707 biolink:molecularly_interacts_with DrugCentral:4196 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyanocobalamin targets Enzyme (Methionine synthase) DrugCentral uuid:f0daa914-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBK8 biolink:molecularly_interacts_with DrugCentral:4196 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyanocobalamin targets Enzyme (Methionine synthase reductase) DrugCentral uuid:f0dacd68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BXJ7 biolink:molecularly_interacts_with DrugCentral:4196 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyanocobalamin targets Unclassified (Protein amnionless) DrugCentral uuid:f0daf1c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96EY8 biolink:molecularly_interacts_with DrugCentral:4196 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyanocobalamin targets Enzyme (Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial) DrugCentral uuid:f0db1746-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH4 biolink:molecularly_interacts_with DrugCentral:4196 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyanocobalamin targets Enzyme (Methylmalonic aciduria type A protein, mitochondrial) DrugCentral uuid:f0db3d16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20062 biolink:molecularly_interacts_with DrugCentral:4196 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyanocobalamin targets Secreted (Transcobalamin-2) DrugCentral uuid:f0db6160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20061 biolink:molecularly_interacts_with DrugCentral:4196 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cyanocobalamin targets Secreted (Transcobalamin-1) DrugCentral uuid:f0db85dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:4197 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vitamin A palmitate targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f0dbaf30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:4197 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vitamin A palmitate targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:f0dbd7d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4199 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 potassium chloride targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f0dc007a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium acetate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:f0dc2910-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium acetate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.44']} DrugCentral uuid:f0dc5638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4207 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lithium carbonate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:f0dc5638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4207 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lithium carbonate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:f0dc85cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29218 biolink:molecularly_interacts_with DrugCentral:4207 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lithium carbonate is inhibitor of Enzyme (Inositol-1(or 4)-monophosphatase 1) DrugCentral uuid:f0dcaa2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f0dcd2c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f0dcfc78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:f0dd2522-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.582']} DrugCentral uuid:f0dd4dd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:f0dd7662-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f0dd9f66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:f0ddc81a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:f0ddf0b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:f0de1946-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f0de4268-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f0de6b26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:f0de93d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:f0debd24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.157']} DrugCentral uuid:f0dee5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.394']} DrugCentral uuid:f0df0e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f0df37e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:f0df60ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:f0df89a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f0dfb24c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f0dfdad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f0e003c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:f0e02c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f0e054fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:f0e07d9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:f0e0a742-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f0e0d05a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:f0e0f904-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:f0e121a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:f0e14abc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f0e17348-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:f0e1a37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:f0e1a37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:f0e1a37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:f0e1eada-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:f0e1eada-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:f0e1eada-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:f0e23350-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f0e23350-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f0e23350-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f0e27b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:f0e27b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:f0e27b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:f0e2c360-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f0e2c360-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f0e2c360-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f0e302ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02665 biolink:molecularly_interacts_with DrugCentral:4209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prazosin targets Unclassified (Beta-casein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:f0e32b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetic acid targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f0e353fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetic acid targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f0e37ca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15552 biolink:molecularly_interacts_with DrugCentral:4211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetic acid is agonist of GPCR (Free fatty acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:f0e3a596-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14843 biolink:molecularly_interacts_with DrugCentral:4211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acetic acid targets GPCR (Free fatty acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:f0e3ce2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4213 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:f0e3f280-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:4213 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone acetate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:f0e422dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:f0e422dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:f0e422dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:f0e45ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4219 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium phosphate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f0e48a1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:4220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telbivudine targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f0e4b2a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:4220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telbivudine is inhibitor of Polyprotein (Protein P) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:f0e4dba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4221 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mequinol is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:f0e50008-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f0e528a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f0e55148-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f0e57a6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f0e5a30a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f0e5cba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone is agonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:f0e5f42c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f0e61e84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f0e64a4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f0e672da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f0e69b5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f0e6c4e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f0e6ed5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f0e715d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:f0e73f80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f0e7687a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f0e79106-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f0e7b988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f0e7e20a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f0e80e4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f0e83dd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f0e83dd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f0e87cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:f0e87cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:f0e87cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:f0e8c404-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f0e8c404-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f0e8c404-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f0e90324-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f0e92c0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f0e95496-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:f0e97d18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f0e9a5ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.31']} DrugCentral uuid:f0e9d0f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f0e9f982-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f0ea2218-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f0ea4ab8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:f0ea73bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f0ea9c66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:f0eac510-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:f0eaedc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f0eb16e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:f0eb3f7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.29']} DrugCentral uuid:f0eb67fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f0eb91e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f0ebbb00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0ebe396-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f0ec0c18-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f0ec3512-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0ec5d94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f0ec8634-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:f0ecafe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0ecd8d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f0ed0172-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f0ed2a1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0ed52b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:f0ed7e36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.89']} DrugCentral uuid:f0eda744-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f0edd0ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f0edf960-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f0ee2264-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f0ee4af0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f0ee7390-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f0ee9c6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f0eec502-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0eeed98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:f0ef1642-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:f0ef407c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f0ef6b38-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:f0ef93ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f0efbc3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f0efe536-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:f0f00db8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0f03658-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f0f05eda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f0f087d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f0f0b060-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f0f0d900-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f0f101a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0f12c2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:f0f154ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f0f17d42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f0f1a5d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0f1cfc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f0f1f84e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f0f220da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f0f249f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0f2727e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:f0f29b14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f0f2c4e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f0f2ef4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f0f3181e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f0f340d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f0f36972-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f0f39276-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f0f3bb20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f0f3e3c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f0f40c6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f0f43564-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f0f45e04-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f0f48712-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f0f4af9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f0f4dbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:f0f5044e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f0f52cda-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:f0f555ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f0f57e60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f0f5a6ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:f0f5d072-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f0f5f94e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f0f621ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f0f64a8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f0f67306-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f0f69dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f0f6c680-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f0f6ef16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f0f717b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f0f740ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f0f76946-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f0f791dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:f0f7ba72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f0f7e362-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f0f80be4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f0f8347a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f0f85d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f0f888c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f0f8b166-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f0f8db0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4225 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 axitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f0f90422-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05129 biolink:molecularly_interacts_with DrugCentral:4226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ingenol mebutate is activator of Kinase (Protein kinase C gamma type) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.79']} DrugCentral uuid:f0f92ccc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05771 biolink:molecularly_interacts_with DrugCentral:4226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ingenol mebutate targets Kinase (Protein kinase C beta type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.836']} DrugCentral uuid:f0f9553a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:4226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ingenol mebutate targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.197']} DrugCentral uuid:f0f97dda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ingenol mebutate targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:f0f9a6c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ingenol mebutate targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:f0f9d046-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ingenol mebutate is activator of Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.328']} DrugCentral uuid:f0f9f8be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62226 biolink:molecularly_interacts_with DrugCentral:4227 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vismodegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f0fa2140-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15465 biolink:molecularly_interacts_with DrugCentral:4227 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vismodegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f0fa4cb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:4227 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vismodegib is inhibitor of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.79']} DrugCentral uuid:f0fa75b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56726 biolink:molecularly_interacts_with DrugCentral:4227 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vismodegib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f0fa9eea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:4228 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivacaftor is positive modulator of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f0fac78a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:4229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tafluprost is agonist of GPCR (Prostaglandin F2-alpha receptor) DrugCentral uuid:f0faec7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:4234 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peginesatide is agonist of Membrane receptor (Erythropoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.43']} DrugCentral uuid:f0fb151e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avobenzone is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:f0fb397c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:4247 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neomycin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f0fb6208-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:4247 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neomycin targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f0fb8b02-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95237 biolink:molecularly_interacts_with DrugCentral:4247 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neomycin targets Enzyme (Lecithin retinol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:f0fbb3a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:4247 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neomycin targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.81']} DrugCentral uuid:f0fbdc38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48442 biolink:molecularly_interacts_with DrugCentral:4247 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neomycin is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:f0fc04ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f0fc3192-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f0fc5d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:f0fc8700-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:f0fcb004-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51787 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f0fcd89a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:f0fd014e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:f0fd29f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:f0fd531a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f0fd7bb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:f0fda46e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f0fdce4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f0fdf7c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f0fe2060-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f0fe4cfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bismuth subsalicylate is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:f0fe4cfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bismuth subsalicylate is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:f0fe7c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thymol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:f0fea5c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8R455 biolink:molecularly_interacts_with DrugCentral:4258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thymol targets Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:f0fece5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4QYD9 biolink:molecularly_interacts_with DrugCentral:4258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thymol targets Unclassified (Heat sensitive channel TRPV3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:f0fef6d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfur targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:f0ff1fc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfur targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:f0ff485a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:4264 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carbamide targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:f0ff70c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentamicin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:f0ff994a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:4265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentamicin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:f0ffc2d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:4265 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gentamicin is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f0ffeb52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:f1001456-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:f1003d0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:f1006636-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:f1008ed6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:f100b780-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f100e016-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:f1010924-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00720 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Endolysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f10131b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:f1015a46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:f10182fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:f101af28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:f101d8fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:f1020194-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenol targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:f1022ade-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4267 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arbutin targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f102536a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:4267 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arbutin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:f1027bba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11344 biolink:molecularly_interacts_with DrugCentral:4267 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arbutin targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f102a482-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f1034f22-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:f104c820-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tapentadol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:f104f0c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tapentadol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:f1051974-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tapentadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:f105432c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tapentadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:f1056bae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 Florbetapir F-18 targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:f105943a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:4289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doconexent targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:f105bcbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:4289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doconexent targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f105e5ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doconexent is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f1060e4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:4289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doconexent targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f10636c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:4289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doconexent targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:f1065f50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDS5 biolink:molecularly_interacts_with DrugCentral:4289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doconexent targets GPCR (Oxoeicosanoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f1068872-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6RI86 biolink:molecularly_interacts_with DrugCentral:4289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doconexent is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:f106b176-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:4289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doconexent targets Nuclear other (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f106db1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4296 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 potassium iodide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:f10703ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:4298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apixaban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f1072d4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apixaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:f10755f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O19045 biolink:molecularly_interacts_with DrugCentral:4298 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apixaban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:f1078a56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:f1078a56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:f1078a56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:f1078a56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:f107d678-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:4300 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elvitegravir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f107ff18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:4300 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elvitegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:f10827b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:4300 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elvitegravir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f10850ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:4300 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elvitegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:f1087970-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4301 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 Flutemetamol (18F) targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:f108a22e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.69']} DrugCentral uuid:f108caec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.25']} DrugCentral uuid:f108f56c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:f1091e34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:f10946f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.91']} DrugCentral uuid:f1099292-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f1099292-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f1099292-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f1099292-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f1099292-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f1099292-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f1099292-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f1099292-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f1099292-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f1099292-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:f10a0f4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4304 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f10a3896-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4304 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:f10a6118-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:4304 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapagliflozin targets Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f10a89a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WWX8 biolink:molecularly_interacts_with DrugCentral:4304 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapagliflozin targets Transporter (Sodium/myo-inositol cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f10ab424-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY91 biolink:molecularly_interacts_with DrugCentral:4304 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapagliflozin targets Transporter (Low affinity sodium-glucose cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.87']} DrugCentral uuid:f10adcce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:4305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avanafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:f10b0546-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51160 biolink:molecularly_interacts_with DrugCentral:4305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avanafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.201']} DrugCentral uuid:f10b2dd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O77746 biolink:molecularly_interacts_with DrugCentral:4305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avanafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:f10b5a82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:4308 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lasofoxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:f10b5a82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:4308 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lasofoxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:f10b8fd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4308 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lasofoxifene is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:f10bb84c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4308 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lasofoxifene is agonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:f10be18c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f10c0ab8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f10c3358-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f10c5c0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f10c8592-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:f10cb102-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f10cd9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f10d0238-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f10d2b32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:f10d53b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f10d7c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:f10da4f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f10dcdf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f10df670-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f10e1f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:f10e47b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:f10e7244-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16555 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Enzyme (Dihydropyrimidinase-related protein 2) DrugCentral uuid:f10e979c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:4310 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lacosamide targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f10ec00a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f10ee88c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f10f11cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f10f3a58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f10f62c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f10f8b48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f10fc3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f10fc3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f10fc3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f10fc3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f10fc3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f11019d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:4317 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 euflavine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f1104308-ac81-11ec-8b6b-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:4317 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 euflavine targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:f1106b8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:4317 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 euflavine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f110940c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f110bcb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:f110e740-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f1110fcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f1113862-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f1116102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f1118a06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f111b292-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f111db3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:f11204e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f1123492-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f1125daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f1128622-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f112af12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f112d794-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f113000c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f1132884-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f113514c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f11379e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f113a25a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f113cae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f113f6c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f1141f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f114480e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f11470a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f1149994-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f114c220-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f114eaac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f11513ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f1153c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f11564e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:f1158d72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f115b7ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f115e02e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f11608a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f1163222-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:f1165b08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:f1168394-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4318 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f116ac34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:4322 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azilsartan medoxomil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:f116d4a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:4322 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 azilsartan medoxomil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:f116ffea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:4326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:f1172862-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:4326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 laropiprant targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:f117510c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:4326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f11779ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:4326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 laropiprant targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:f117a35a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:4326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 laropiprant targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:f117cbfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:4326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:f117f490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:4326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 laropiprant targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:f1181db2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:4326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 laropiprant is antagonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.52']} DrugCentral uuid:f1184666-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:4329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f1186efc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:4329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f118977e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:4329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:f118c06e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:4329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f118e8e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:4329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:f1191208-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4334 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bazedoxifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f1193a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4334 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bazedoxifene is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f119fda8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:f11ba77a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ambrisentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:f11bd074-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ambrisentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.65']} DrugCentral uuid:f11bf93c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4340 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alogliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f11c21d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:4342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zucapsaicin is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.71']} DrugCentral uuid:f11c4a54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zinc chloride targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.158']} DrugCentral uuid:f11c7358-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zinc chloride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.936']} DrugCentral uuid:f11c9bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zinc chloride targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f11cc42a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zinc chloride targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.726']} DrugCentral uuid:f11cec98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zinc chloride targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.363']} DrugCentral uuid:f11d17b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:4344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zinc chloride targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.958']} DrugCentral uuid:f11d431e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43194 biolink:molecularly_interacts_with DrugCentral:4344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zinc chloride targets GPCR (G-protein coupled receptor 39) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:f11d6baa-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6QR73 biolink:molecularly_interacts_with DrugCentral:4344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zinc chloride targets GPCR (G protein-coupled receptor 39-1b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f11d9422-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPD8 biolink:molecularly_interacts_with DrugCentral:4344 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zinc chloride targets Unclassified (Ubiquitin-conjugating enzyme E2 T) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f11dbd08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:4347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzathine benzylpenicillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f11dfcd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f11dfcd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f11dfcd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f11dfcd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f11dfcd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f11dfcd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f11dfcd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:f11e5dda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4349 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.5']} DrugCentral uuid:f11e865c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4349 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aurothioglucose targets Enzyme (Thioredoxin reductase 1, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:f11eaede-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:4349 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.85']} DrugCentral uuid:f11ed97c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:4349 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.85']} DrugCentral uuid:f11f01fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6N5 biolink:molecularly_interacts_with DrugCentral:4349 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aurothioglucose targets Unclassified (Sulfide:quinone oxidoreductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:f11f2a8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bilastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:f11f5316-ac81-11ec-8b6b-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:4357 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anidulafungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:f11f7bde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:4358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arginine glutamate targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:f11fa4d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f11fcd5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f11ff668-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f1201f80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.54']} DrugCentral uuid:f12047f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f1207066-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:f1209910-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:f120c476-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.23']} DrugCentral uuid:f120efaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:f121182c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f1214090-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:f1216980-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f1219202-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:f121ba84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f121e37e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:f1220c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f12234aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f1225d40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f122873e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f122afc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:f122d950-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f12301e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.47']} DrugCentral uuid:f1232ad6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f1235362-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:f1237bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f123a452-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f123cd38-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f123f5c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f1241fa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f124484e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:f1247468-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f1249fe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:f124c86e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f124f172-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f12519f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f1254294-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.38']} DrugCentral uuid:f1256b20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f1259406-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f125bc9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f125e532-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f1260daa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f1263758-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:f1265fe4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:f12688e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f126b174-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f126db5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f12703d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:f1272c6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:f127550c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f1277de8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f127a674-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f127cf00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:f127f78c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f1282180-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:f1284a0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:f12872a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f1289ba6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:f128c450-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f128ecd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:f1291568-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:f1293e4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f12966d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49761 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f1298f66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f129b810-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f129e2fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.89']} DrugCentral uuid:f12a0ec8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f12a3754-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:f12a5fe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:f12a88f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f12ab198-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f12adb0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:f12b03b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.33']} DrugCentral uuid:f12b2cae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f12b554e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:f12b7dda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f12ba7ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.04']} DrugCentral uuid:f12bd082-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f12bf90e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f12c219a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f12c4a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:f12c7302-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:f12c9ba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f12cc41a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f12ced1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:f12d158c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f12d3e2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:f12d6726-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f12d92a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:f12dbde8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:f12de674-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f12e0f00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f12e37fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f12e6090-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:f12e8930-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f12eb20c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f12edb7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f12f040a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:f12f2ca0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f12f56da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f12f80ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f12fa95a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f12fd1e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:f12ffaea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f13024ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f1304d38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f13075ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f1309ec8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N752 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Casein kinase I isoform alpha-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f130c75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f130eff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f1311880-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f1314436-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f1316cc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f1319558-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f131be48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:f131e6de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f1320f60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:f13237e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f13260e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f1328986-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f132b1fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:f132db8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:f133060e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f1332ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f133576c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f1337fee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:f133a8ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f133d156-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f133f9ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:f1342278-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99640 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f1344bf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.29']} DrugCentral uuid:f1347476-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:f1349d02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f134c598-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:f134ef5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f13517e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f1354068-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f135698a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f135923e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f135bade-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f135e34c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f1360c46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f1363608-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f1365e94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f1368734-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f136b114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f136daa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f1370330-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f1372bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f13754c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f1377d56-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f137a5e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f137ce6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f137f75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:f1381fea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.49']} DrugCentral uuid:f138484e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f13870e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16277 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:f1389ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f138c346-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f138ebb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f13914b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:f1393d3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f13965c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f1398e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f139b756-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f139dfe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f13a085a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:f13a30fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:f13a5bde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f13a8780-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:f13ab002-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f13ad988-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f13b026e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f13b2b86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f13b5408-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f13b7c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f13ba58e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f13bce2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f13bf6ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f13c205e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:f13c4be2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f13c74a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f13c9d22-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f13cc61c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f13ceec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f13d1752-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.11']} DrugCentral uuid:f13d3fde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f13d68e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:f13d9164-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f13db9f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f13de272-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:f13e0d6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:f13e35e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f13e5e78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BQI3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:f13e86fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f13eafd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:f13ed95c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f13f01f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f13f2a7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f13f5382-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:f13f7ff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f13f7ff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f13fb7b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:f13fb7b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:f13ff3c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f13ff3c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bosutinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f1402956-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05193 biolink:molecularly_interacts_with DrugCentral:4360 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetrimide targets Structural (Dynamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f14051d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:4361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chenodiol is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:f1407adc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:4361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chenodiol is agonist of Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f140a35e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:4361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chenodiol is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f140cbb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:4362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chiniofon targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:f140f444-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:4365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vernakalant targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:f1411d16-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vernakalant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:f14145ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZV8 biolink:molecularly_interacts_with DrugCentral:4365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vernakalant targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:f1416e4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vernakalant is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.875']} DrugCentral uuid:f1419750-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:4366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voclosporin is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f141c108-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:4366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voclosporin is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f141e994-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f142134c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:f1423c64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4373 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.61']} DrugCentral uuid:f14264fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorcaserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:f1428e9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorcaserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:f142b734-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorcaserin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:f142e042-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4374 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorcaserin is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:f14308e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:4376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dequalinium targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f1433164-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:4376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dequalinium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f14359f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:4376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dequalinium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f1438420-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:4376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dequalinium is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f143acb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:4376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dequalinium is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f143d54c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29973 biolink:molecularly_interacts_with DrugCentral:4376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dequalinium is blocker of Ion channel (cGMP-gated cation channel alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f143fdba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16280 biolink:molecularly_interacts_with DrugCentral:4376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dequalinium is blocker of Ion channel (Cyclic nucleotide-gated olfactory channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f14426b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:4379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 degarelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f1444f40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desvenlafaxine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.325']} DrugCentral uuid:f14477ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desvenlafaxine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:f144a076-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 desvenlafaxine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:f144c966-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4381 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dapoxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.95']} DrugCentral uuid:f144f1f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirabegron is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.65']} DrugCentral uuid:f1451a88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f145433c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f1456d58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f14595f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f145be8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:f145e788-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:f146100a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:f1463896-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f146623a-ac81-11ec-8b6b-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f1468b02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:f146b3b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:f146dc42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f14708ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:f14708ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:f14744c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:f14744c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:f1477ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:f1477ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:f1477ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:f1477ec2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:f147cab2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:f147fee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f147fee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f147fee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f147fee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f1484d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f1484d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f1488934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f1488934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f1488934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f148c804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:4390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline theophyllinate targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:f148f19e-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.026']} DrugCentral uuid:f1491c50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:f14945d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f1496e62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:f149934c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f149bbce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:f149e02c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:f14a048a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.582']} DrugCentral uuid:f14a2d66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.639']} DrugCentral uuid:f14a55e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.321']} DrugCentral uuid:f14a7e6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25025 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets GPCR (C-X-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.024']} DrugCentral uuid:f14aa6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.029']} DrugCentral uuid:f14ad0e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.154']} DrugCentral uuid:f14af980-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.335']} DrugCentral uuid:f14b2202-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cisplatin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.219']} DrugCentral uuid:f14b4ab6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clofenotane targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:f14b73a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clopenthixol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f14b9c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltrombopag targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:f14bc4d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:4399 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eltrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:f14bed4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:4401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 casopitant targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:f14c1658-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 casopitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:f14c3eda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7DHH4 biolink:molecularly_interacts_with DrugCentral:4402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceftobiprole medocaril targets Enzyme (MecA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f14c6766-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61073 biolink:molecularly_interacts_with DrugCentral:4410 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 plerixafor is partial agonist of GPCR (C-X-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f14c911e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:4410 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 plerixafor targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:f14cbcd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48061 biolink:molecularly_interacts_with DrugCentral:4410 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 plerixafor targets Cytokine (Stromal cell-derived factor 1) DrugCentral uuid:f14ce2f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:4410 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 plerixafor is antagonist of GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f14d0b76-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08565 biolink:molecularly_interacts_with DrugCentral:4410 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 plerixafor targets GPCR (C-X-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:f14d3402-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25106 biolink:molecularly_interacts_with DrugCentral:4410 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 plerixafor is agonist of GPCR (Atypical chemokine receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f14d5e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.118']} DrugCentral uuid:f14d86c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.157']} DrugCentral uuid:f14daf54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:f14dd86c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.308']} DrugCentral uuid:f14e0102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.977']} DrugCentral uuid:f14e29a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.915']} DrugCentral uuid:f14e5238-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.677']} DrugCentral uuid:f14e7bfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:f14ea4a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.085']} DrugCentral uuid:f14ecd1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.478']} DrugCentral uuid:f14ef5a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:f14f1e8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.262']} DrugCentral uuid:f14f471a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:f14f6fa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.126']} DrugCentral uuid:f14f983c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.131']} DrugCentral uuid:f14fc136-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.781']} DrugCentral uuid:f14fe9cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.065']} DrugCentral uuid:f150126c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:4411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexchlorpheniramine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.931']} DrugCentral uuid:f1503aee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diamorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f15065d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:4412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diamorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f1508e7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:4412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diamorphine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:f150b708-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dibutylphthalate is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:f150dfda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocryptine is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:f1510870-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocryptine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:f151320a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:4420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dihydroergocryptine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:f1515a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colistin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:f1518368-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colistin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.018']} DrugCentral uuid:f151abea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colistin targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.652']} DrugCentral uuid:f151d462-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colistin targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.092']} DrugCentral uuid:f151fce4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colistin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.604']} DrugCentral uuid:f1522778-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 colistin targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.775']} DrugCentral uuid:f15252e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f1527d2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f152a662-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f152cf98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f152f82e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:f15320d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:f1534950-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:f1537240-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f1539acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f153c34e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:f153ec8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:f154170e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f1544378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:f1544378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:f1547b68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:f1547b68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:f154b5c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:f154b5c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:f154b5c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:f154b5c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:f1550182-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:f15535e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f15535e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f15535e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f15535e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f1558468-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f1558468-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:f155bff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f155bff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f155bff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f15600d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:4426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bufylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:f1562968-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30988 biolink:molecularly_interacts_with DrugCentral:4427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin human is agonist of GPCR (Calcitonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:f15655e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:4427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.53']} DrugCentral uuid:f15655e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:4427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.53']} DrugCentral uuid:f1568e3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:4427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.082']} DrugCentral uuid:f1568e3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:4427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.082']} DrugCentral uuid:f156c5ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:4427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.706']} DrugCentral uuid:f156c5ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:4427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.706']} DrugCentral uuid:f156fa14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prednisolone sodium phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:f1571fbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobetasol propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.179']} DrugCentral uuid:f1574852-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:4452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobetasol propionate targets Cytosolic other (Annexin A1) DrugCentral uuid:f1576cb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:4452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobetasol propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:f157953c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobetasol propionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.599']} DrugCentral uuid:f157c17e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:4452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobetasol propionate targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:f157ea00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobetasol propionate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.818']} DrugCentral uuid:f1581390-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:4452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobetasol propionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:f1583c62-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:4452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobetasol propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:f1586584-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:4452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clobetasol propionate targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:f1588dfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4454 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone cypionate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:f158b278-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4456 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone succinate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:f158d744-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:4456 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone succinate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f158ffee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:4458 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfisoxazole acetyl is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:f159244c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4458 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:f1594cc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4458 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:f15976fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:4458 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:f159a1ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:4466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eosin targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f159ca32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5VLE3 biolink:molecularly_interacts_with DrugCentral:4466 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eosin targets Enzyme (RmtA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:f15a0a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:f15a0a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:f15a0a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:f15a0a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:f15a0a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:f15a0a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:f15a0a42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:f15a7630-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4470 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosaprepitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:f15a9ebc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4474 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trisodium citrate dihydrate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:f15ac7d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4474 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trisodium citrate dihydrate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:f15af056-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium citrate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:f15b18ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4477 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium citrate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:f15b42cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19111 biolink:molecularly_interacts_with DrugCentral:4480 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 potassium phosphate, monobasic targets Enzyme (Intestinal alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f15b6cd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corbadrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f15b9e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:f15b9e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:f15b9e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:f15be57e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f15be57e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f15be57e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f15c2dcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:f15c2dcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:f15c2dcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:f15c65ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f15c8ee8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f15cb774-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28062 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f15ce000-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:f15d0896-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:f15d3230-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f15d5aa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:f15d8316-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28065 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f15dab98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40306 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f15dd474-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f15dfda0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:4483 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 carfilzomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:f15e2622-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:f15e4f12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:f15e77bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclidinium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:f15ea048-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f15ec8c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4484 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:f15ef25a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4485 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diflorasone diacetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.536']} DrugCentral uuid:f15f1bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4485 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diflorasone diacetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:f15f4480-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4493 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alclometasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:f15f68e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol decanoate is inverse agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:f15f91e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol decanoate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:f15fba78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol decanoate targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:f15fe30e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:4496 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 haloperidol decanoate targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f1600bae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4497 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estradiol acetate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:f1603066-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4498 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone palmitate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f1605906-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4498 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone palmitate is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:f1607d82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4498 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paliperidone palmitate is antagonist of GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:f160a1ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4501 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 armodafinil targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.921']} DrugCentral uuid:f160cc1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4501 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 armodafinil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:f160f51e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4501 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 armodafinil is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.497']} DrugCentral uuid:f1611d8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4501 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 armodafinil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:f16141ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:4501 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 armodafinil targets Enzyme (Cytochrome P450 1A2) DrugCentral uuid:f16167ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:4501 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 armodafinil targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:f1618c40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:4501 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 armodafinil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f161b4d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4504 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone valerate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:f161d95c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline fenofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:f1620292-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:4505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline fenofibrate targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:f1622b28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:4505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline fenofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f16253be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:4505 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choline fenofibrate targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f1627c40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4507 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halcinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.135']} DrugCentral uuid:f162a710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4507 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halcinonide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:f162d2da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4507 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 halcinonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.917']} DrugCentral uuid:f162fb8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racepinefrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:f1632514-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racepinefrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:f1634e18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4508 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 racepinefrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f1637b22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4512 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lithium citrate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:f1637b22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4512 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lithium citrate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:f163a976-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29218 biolink:molecularly_interacts_with DrugCentral:4512 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lithium citrate is inhibitor of Enzyme (Inositol-1(or 4)-monophosphatase 1) DrugCentral uuid:f163ce92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:4514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f163f714-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49190 biolink:molecularly_interacts_with DrugCentral:4514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f1641f8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P70555 biolink:molecularly_interacts_with DrugCentral:4514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f16447e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25961 biolink:molecularly_interacts_with DrugCentral:4514 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f1647158-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4516 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracosactide targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.19']} DrugCentral uuid:f16499da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4516 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tetracosactide is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.268']} DrugCentral uuid:f164c252-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:f164e6b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:f1650f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:4523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:f16533e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92953 biolink:molecularly_interacts_with DrugCentral:4523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinine is blocker of Ion channel (Potassium voltage-gated channel subfamily B member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:f1655c62-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:f1658caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f1658caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f1658caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f165ccd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:4523 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quinine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:f165f55a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenbendazole targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.496']} DrugCentral uuid:f1661de6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10424 biolink:molecularly_interacts_with DrugCentral:4536 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fenbendazole targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:f16647c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4554 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone furoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.12']} DrugCentral uuid:f16670f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:4554 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:f1669992-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4554 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:f166c32c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4554 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone furoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:f166ed0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:4554 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone furoate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f1671598-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4554 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:f1673e10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:f167669c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f1678fc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f167b85e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:f167ec70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f167ec70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f167ec70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f167ec70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f1684314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f1684314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f1684314-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f1688acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium oxybate is agonist of GPCR (GABA-B receptor) DrugCentral uuid:f1688acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium oxybate is agonist of GPCR (GABA-B receptor) DrugCentral uuid:f168b970-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6RY99 biolink:molecularly_interacts_with DrugCentral:4566 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium oxybate targets Unclassified (Gamma-hydroxybutyrate receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:f168e1ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4568 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrochloric acid targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f1690a7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4569 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 hydrocortisone probutate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:f1692f5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4573 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:f169589e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:4573 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f1698120-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:4573 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:f169a9a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:4573 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:f169ddc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f169ddc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f169ddc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f169ddc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f16a3016-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f16a5898-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f16a8174-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:f16aaa0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O88944 biolink:molecularly_interacts_with DrugCentral:4588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linopirdine is inhibitor of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f16ad296-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97414 biolink:molecularly_interacts_with DrugCentral:4588 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linopirdine is inhibitor of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:f16afb04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:4601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diosmetin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f16b243a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:4601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diosmetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:f16b4c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diosmetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:f16b7516-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diosmetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:f16b9d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFU5 biolink:molecularly_interacts_with DrugCentral:4601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diosmetin targets Kinase (Inositol polyphosphate multikinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f16bc782-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHH9 biolink:molecularly_interacts_with DrugCentral:4601 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diosmetin targets Kinase (Inositol hexakisphosphate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f16bf02c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tonzonium targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:f16c19b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:4605 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tonzonium targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:f16c4234-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4606 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clocortolone pivalate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:f16c6700-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:4608 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trypan blue targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f16c8f96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25044 biolink:molecularly_interacts_with DrugCentral:4608 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trypan blue targets Enzyme (Tyrosine-protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:f16cb82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4609 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 testosterone enantate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:f16cdc94-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f16d05ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f16d2e4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:4611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stearic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.1']} DrugCentral uuid:f16d56ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:f16d7f64-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4611 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 stearic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f16daa7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27471 biolink:molecularly_interacts_with DrugCentral:4615 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 N-Acetylglucosamine targets Unclassified (Killer cell lectin-like receptor subfamily B member 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f16dd40a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylnaltrexone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:f16dfc82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylnaltrexone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f16e24f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylnaltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:f16e4e08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:4616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylnaltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f16e7694-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:4616 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylnaltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f16e9fca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f16ec900-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:4618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linolenic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:f16ef182-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.1']} DrugCentral uuid:f16f1a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f16f42ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05413 biolink:molecularly_interacts_with DrugCentral:4618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linolenic acid targets Cytosolic other (Fatty acid-binding protein, heart) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.56']} DrugCentral uuid:f16f6c84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f16f9556-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linolenic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f16fbdba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:4618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linolenic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f16fe65a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:4618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:f1700f40-ac81-11ec-8b6b-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:4618 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:f17037e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:4619 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomenol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f170606c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:4619 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomenol targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:f17088f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:4619 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomenol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f170b206-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:4621 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomefolic acid targets Enzyme (Thymidylate synthase) DrugCentral uuid:f170d66e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23897 biolink:molecularly_interacts_with DrugCentral:4622 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linaclotide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:f170ff04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25092 biolink:molecularly_interacts_with DrugCentral:4622 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 linaclotide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.907']} DrugCentral uuid:f1713bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:f1713bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:f1713bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:f1713bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:f1713bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:f1713bfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:f1719766-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:4624 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenylacetic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:f171bfe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:4627 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:f171e900-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:4627 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:f17211a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:4627 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:f1723a40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:4627 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:f17262d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f1728c20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63931 biolink:molecularly_interacts_with DrugCentral:4627 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:f172b88a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sincalide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f172b88a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sincalide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f172ec9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4628 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enzalutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.31']} DrugCentral uuid:f1731654-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4628 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enzalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:f1733ecc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:4630 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium pyrophosphate targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:f1736758-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:4631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroprusside targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:f1739764-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:f1739764-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:f1739764-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:f1739764-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:f173d9f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trabectedin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f1740280-ac81-11ec-8b6b-0242ac110002 UniProtKB:O54915 biolink:molecularly_interacts_with DrugCentral:4633 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trabectedin is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f1742bac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:4634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teriflunomide is inhibitor of Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f17454e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teriflunomide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f1747d64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:4634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:f174a5d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35435 biolink:molecularly_interacts_with DrugCentral:4634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:f174ce54-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q54A96 biolink:molecularly_interacts_with DrugCentral:4634 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:f174f848-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:4635 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 Choline C-11 targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f17521c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:4637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rose bengal targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f1754a3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:4637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rose bengal targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f17572aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99895 biolink:molecularly_interacts_with DrugCentral:4637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rose bengal targets Enzyme (Chymotrypsin C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:f1759b9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16278 biolink:molecularly_interacts_with DrugCentral:4637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rose bengal targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:f175c426-ac81-11ec-8b6b-0242ac110002 UniProtKB:O06446 biolink:molecularly_interacts_with DrugCentral:4637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rose bengal targets Unclassified (Protein translocase subunit SecA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f175ecb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2FUW6 biolink:molecularly_interacts_with DrugCentral:4637 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rose bengal targets Unclassified (Protein translocase subunit SecA 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f176153e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:4641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f1763e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:4641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:f17666e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:4641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f1768f6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:4641 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levmetamfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f176b8d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f176e4c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f1770d68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f17735ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dodecanoic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f1775ea8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:4642 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dodecanoic acid is agonist of GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:f1778720-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4647 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluorometholone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:f177af98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4648 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eugenol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f177d824-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4648 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eugenol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:f178015a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4648 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eugenol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:f17829c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f178524a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f1787acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:f178a5ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f178ce6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:f178f89e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:f1792120-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f1794a10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:f179726a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f1799ad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f179c3dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib is inhibitor of Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f179ec72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f17a14ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f17a3d3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f17a66b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f17a8f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f17ab7d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f17ae064-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f17b08f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f17b31a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:f17b5a1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4654 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 regorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f17b82a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:4655 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tedisamil is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:f17babde-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4659 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metamizole is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.041']} DrugCentral uuid:f17bd460-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:f17bfcec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:4660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:f17c256e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:4660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.59']} DrugCentral uuid:f17c50c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:4660 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:f17c7ca8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:4663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzoin targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f17ca746-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:4663 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzoin targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:f17cd202-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:4664 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzoic acid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:f17cfa98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:4664 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzoic acid targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f17d2324-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:4664 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benzoic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:f17d4b9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone phosphate targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.932']} DrugCentral uuid:f17d74f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.776']} DrugCentral uuid:f17d9d7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:f17dc608-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.779']} DrugCentral uuid:f17dee9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.248']} DrugCentral uuid:f17e1892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4667 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betamethasone phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.428']} DrugCentral uuid:f17e40f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:4671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metizoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:f17e6a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:4671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metizoline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:f17e9286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:4671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metizoline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:f17ebb4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:4671 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metizoline targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:f17ee3da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f17f0c5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.14']} DrugCentral uuid:f17f34ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:f17f5dc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:f17f863c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:f17faea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:f17fd6fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:f18000b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:f180292a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:f18051ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:f1807ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:f180a346-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f180cca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:f180f544-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:f1811e16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:f18146a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f1816f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4673 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nalfurafine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:f18197a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4676 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 obidoxime targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.67']} DrugCentral uuid:f181c0e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:f181e954-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f18211cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:A5H660 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat targets Unclassified (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f1823a58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:f1826370-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:f1828c10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:f182b5f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:f182de90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:f18307f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:f18330b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:f1835956-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:f1838200-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:f183ae6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:f183d8e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4682 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:f1840162-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:f1842a52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f18452c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paraoxon targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f1847b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:4683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paraoxon targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:f184a3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:4683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:f184cdc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:4683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paraoxon targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f184f61c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paraoxon targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f1851e8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O35678 biolink:molecularly_interacts_with DrugCentral:4683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paraoxon targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f18546f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O08914 biolink:molecularly_interacts_with DrugCentral:4683 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 paraoxon targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:f1857c68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:f1857c68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:f1857c68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:f1857c68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:f185c6a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:4690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pleconaril targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f185ef0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:4690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pleconaril targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:f18617d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7T664 biolink:molecularly_interacts_with DrugCentral:4690 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pleconaril targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:f1864058-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:4696 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remikiren is inhibitor of Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:f18668c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esatenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f1869152-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esatenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:f186baa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esatenolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:f186e33c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esatenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:f1870bdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esatenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.93']} DrugCentral uuid:f187358a-ac81-11ec-8b6b-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:4702 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esatenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:f1875ec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4704 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 semustine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.744']} DrugCentral uuid:f1878756-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium aurothiomalate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.074']} DrugCentral uuid:f187afd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium aurothiomalate targets Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:f187d4ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium aurothiomalate targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.624']} DrugCentral uuid:f187fd26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium aurothiomalate targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:f188259e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4706 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium aurothiomalate targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f1884f38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32241 biolink:molecularly_interacts_with DrugCentral:4710 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatorelin is agonist of GPCR (Vasoactive intestinal polypeptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:f1887968-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:f188a1fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f188ca8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:f188f302-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f1891c88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f189450a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f1896da0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f189969a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:f189bfb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f189e83e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:f18a10c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:f18a3938-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f18a626e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:f18a8ae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:f18ab37c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f18adca8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:f18b0836-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f18b3112-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f18b59a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f18b8266-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:f18baaf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f18bd360-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:f18bfbe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f18c24f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f18c4d90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:f18c77de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f18ca100-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f18ccb6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f18cf402-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:f18d1c66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f18d4506-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:f18d6e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62137 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:f18d96aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:f18dbf4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:f18de808-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f18e1490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:f18e1490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:f18e5180-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:f18e5180-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:f18e5180-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:f18e9668-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f18e9668-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f18ecb24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63272 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f18ef798-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.391']} DrugCentral uuid:f18ef798-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.391']} DrugCentral uuid:f18f3082-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:f18f3082-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofacitinib is inhibitor of Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:f18f6462-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib is inhibitor of Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.907']} DrugCentral uuid:f18f8cd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:f18fb552-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:f18fdf46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f19007dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:f190304a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:f1905994-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f190852c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:f190afc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:f190d842-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.337']} DrugCentral uuid:f191011e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.947']} DrugCentral uuid:f19129aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:f1915218-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.456']} DrugCentral uuid:f1917aa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.845']} DrugCentral uuid:f191a380-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4715 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabozantinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.886']} DrugCentral uuid:f191cc16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:f191f4ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.432']} DrugCentral uuid:f1921d24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.903']} DrugCentral uuid:f19247f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Breakpoint cluster region protein) DrugCentral uuid:f1926c3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f19294b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f192bd2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:f192e61e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:f1930e96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:f1933704-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:f1935f72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.268']} DrugCentral uuid:f193886c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:f193b2ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.658']} DrugCentral uuid:f193db64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:f194051c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:f1942dee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:f1945666-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f1947efc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49336 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Cyclin-dependent kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.17']} DrugCentral uuid:f194a814-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f194d096-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:f194fce2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f194fce2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f19530b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4716 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponatinib is inhibitor of Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f1955a52-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95838 biolink:molecularly_interacts_with DrugCentral:4718 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teduglutide is agonist of GPCR (Glucagon-like peptide 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:f19582b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z0W0 biolink:molecularly_interacts_with DrugCentral:4718 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teduglutide targets GPCR (Glucagon-like peptide 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.1']} DrugCentral uuid:f195ab24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicinol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:f195cf82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:4719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicinol targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:f195f57a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:4719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicinol targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:f19619c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:4719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicinol targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:f1963e18-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:4719 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daunorubicinol targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:f1966280-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55157 biolink:molecularly_interacts_with DrugCentral:4721 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lomitapide is inhibitor of Cytosolic other (Microsomal triglyceride transfer protein large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:f1968b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:4723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 succinimide targets Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.58']} DrugCentral uuid:f196b3fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4723 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 succinimide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f196dc88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:4727 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tacalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.5']} DrugCentral uuid:f1970578-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.573']} DrugCentral uuid:f1972e68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:f19756ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:4728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenidap targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:f1977f76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:4728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenidap targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f197a8f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:4728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenidap targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:f197d43a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O97554 biolink:molecularly_interacts_with DrugCentral:4728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f197fcda-ac81-11ec-8b6b-0242ac110002 UniProtKB:O02768 biolink:molecularly_interacts_with DrugCentral:4728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f198294e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:4728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenidap targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f198294e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:4728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenidap targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f1985d88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48050 biolink:molecularly_interacts_with DrugCentral:4728 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenidap is activator of Ion channel (Inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f198bf80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f1999dce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:f1999dce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:f1999dce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:f199e7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:f199e7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:f199e7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:f19a2f32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:f19a2f32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:f19a2f32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:f19a6e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioctic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f19a9a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:4732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioctic acid targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:f19a9a80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:4732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioctic acid targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:f19acee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:4732 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thioctic acid targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f19af75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:f19b1ffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.971']} DrugCentral uuid:f19b4890-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.035']} DrugCentral uuid:f19b7432-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:f19ba02e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.071']} DrugCentral uuid:f19bcaa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:f19bf394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.135']} DrugCentral uuid:f19c1c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:f19c44a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.718']} DrugCentral uuid:f19c6d38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:f19c965a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:f19cbf5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f19ce7ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:f19d11a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f19d3c86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f19d6530-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f19d8dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:f19db67a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:f19ddf74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.111']} DrugCentral uuid:f19e080a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:f19e3096-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q932Y6 biolink:molecularly_interacts_with DrugCentral:4733 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thiomersal targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:f19e590e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f19e9d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:f19e9d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:f19e9d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:f19e9d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:f19e9d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:f19e9d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:f19e9d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:f19e9d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:f19f075a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5TIX5 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline targets Enzyme (ATP synthase subunit c) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:f19f331a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00845 biolink:molecularly_interacts_with DrugCentral:4741 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bedaquiline targets Enzyme (ATP synthase subunit c) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f19f5f02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:4744 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crofelemer is inhibitor of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:f19f8acc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5XXA6 biolink:molecularly_interacts_with DrugCentral:4744 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crofelemer is inhibitor of Ion channel (Anoctamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:f19fb4f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pomalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f19fdd92-ac81-11ec-8b6b-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pomalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f1a00650-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:4746 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pomalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.577']} DrugCentral uuid:f1a02edc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4749 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ospemifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.082']} DrugCentral uuid:f1a05812-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4752 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobetaxolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:f1a080bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4752 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levobetaxolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:f1a0a970-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:4757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimethyl fumarate targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f1a0d300-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14145 biolink:molecularly_interacts_with DrugCentral:4757 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dimethyl fumarate is inhibitor of Cytosolic other (Kelch-like ECH-associated protein 1) DrugCentral uuid:f1a0faf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 canagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.658']} DrugCentral uuid:f1a1242c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 canagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f1a14cae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:4758 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 canagliflozin targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:f1a175b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4773 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:f1a19e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4773 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethyl hydroxybenzoate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:f1a1c6d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4773 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f1a1ef74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4773 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethyl hydroxybenzoate targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:f1a21882-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4773 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:f1a242c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4773 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:f1a26b70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4773 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:f1a2941a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4773 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:f1a2bd96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:4778 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ridaforolimus is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:f1a2e60e-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:4794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gramicidin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.289']} DrugCentral uuid:f1a30ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gramicidin targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:f1a33730-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gramicidin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.961']} DrugCentral uuid:f1a36016-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gramicidin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.477']} DrugCentral uuid:f1a388a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:4794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gramicidin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.111']} DrugCentral uuid:f1a3b110-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:4794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gramicidin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:f1a3d9a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gramicidin targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:f1a402d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4794 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gramicidin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:f1a42b68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium propionate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.29']} DrugCentral uuid:f1a45412-ac81-11ec-8b6b-0242ac110002 UniProtKB:B2GV46 biolink:molecularly_interacts_with DrugCentral:4796 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium propionate targets GPCR (Free fatty acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f1a47c80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['1.2']} DrugCentral uuid:f1a4a76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.08']} DrugCentral uuid:f1a4d108-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:4797 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['1.9']} DrugCentral uuid:f1a4f99e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilanterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f1a52284-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilanterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:f1a54afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4799 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vilanterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f1a57388-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f1a59c1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:f1a5c536-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:f1a5edcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f1a6164e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:f1a63ee4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:f1a66892-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:f1a69182-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:f1a6ba0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f1a6e290-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:f1a70ba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:f1a7343e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:f1a75cc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4801 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f1a78556-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trametinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:f1a7ae96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trametinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:f1a7d72c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trametinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.036']} DrugCentral uuid:f1a7ffb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4802 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trametinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:f1a82a6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4804 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palifermin is agonist of Kinase (Fibroblast growth factor receptor 2) DrugCentral uuid:f1a84f86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dolutegravir targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f1a87812-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:4805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dolutegravir targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f1a8a1c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:4805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dolutegravir targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f1a8cae2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:4805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dolutegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:f1a8f364-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:4805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dolutegravir targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:f1a91c18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:4805 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dolutegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.131']} DrugCentral uuid:f1a9449a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:f1a96dc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f1a99670-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f1a9bef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f1a9e77e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f1aa1154-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f1aa39ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f1aa626c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f1aa8b0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:f1aab410-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f1aadca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35563 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f1ab0532-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f1ab2dc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:f1ab56f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:f1ab7fa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:f1aba834-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:f1abd188-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:f1abfdf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:f1ac26d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4806 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.268']} DrugCentral uuid:f1ac4f78-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:4807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riociguat targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 7B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:f1ac7872-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4807 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 riociguat is positive allosteric modulator of Enzyme (Guanylate cyclase soluble subunit beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'MEC', 'has_quantitative_value': ['7.523']} DrugCentral uuid:f1aca1f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f1acca70-ac81-11ec-8b6b-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f1acf2de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:4808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipidacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f1ad1c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:4808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipidacrine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.658']} DrugCentral uuid:f1ad4482-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:4808 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.569']} DrugCentral uuid:f1ad6d36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 macitentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:f1ad95e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4809 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 macitentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.408']} DrugCentral uuid:f1adbf98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f1ade874-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:f1ae10ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:f1ae3afe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:f1ae6876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:f1ae9102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:f1aeb9c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:f1aee2b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f1af0b82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:f1af3422-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BRX8 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Unclassified (Redox-regulatory protein FAM213A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f1af5cae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:f1af86d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.495']} DrugCentral uuid:f1afb1ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.721']} DrugCentral uuid:f1afda4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:f1b002d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.387']} DrugCentral uuid:f1b02c1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:f1b054a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.194']} DrugCentral uuid:f1b07ddc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:f1b0a74e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:f1b0d052-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:f1b0f8d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:f1b1216a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.155']} DrugCentral uuid:f1b149e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:f1b175f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:f1b19eba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4810 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.143']} DrugCentral uuid:f1b1c76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sofosbuvir is inhibitor of Enzyme (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:f1b1f0c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4811 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sofosbuvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC90', 'has_quantitative_value': ['6.959']} DrugCentral uuid:f1b21930-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simeprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f1b24626-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simeprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f1b24626-ac81-11ec-8b6b-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simeprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f1b27a1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simeprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:f1b2a31e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6GYR8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simeprevir is inhibitor of Polyprotein (Polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:f1b2cbd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4812 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 simeprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:f1b2f490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:4813 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 luliconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:f1b31902-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olodaterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:f1b34602-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olodaterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:f1b36ed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4814 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olodaterol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:f1b39788-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4815 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lixisenatide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.845']} DrugCentral uuid:f1b3c05a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:f1b3e8fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:f1b412c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 umeclidinium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.796']} DrugCentral uuid:f1b43b66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 umeclidinium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.824']} DrugCentral uuid:f1b46488-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4816 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.222']} DrugCentral uuid:f1b48df0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:4817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifamycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f1b4b67c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:4817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifamycin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f1b4df30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:4817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifamycin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f1b50a78-ac81-11ec-8b6b-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:4817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifamycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f1b534bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:4817 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rifamycin is inhibitor of Enzyme (DNA-directed RNA polymerase subunit beta) DrugCentral uuid:f1b5591a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4818 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 florbetaben F18 targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:f1b581ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:4820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tasimelteon is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.45']} DrugCentral uuid:f1b5aae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:4820 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tasimelteon is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:f1b5d386-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4821 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 seractide is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.009']} DrugCentral uuid:f1b5fc1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:4822 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 laninamivir octanoate hydrate targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:f1b6249e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:4822 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 laninamivir octanoate hydrate targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f1b64dac-ac81-11ec-8b6b-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:4823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:f1b67638-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:4823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peramivir targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:f1b69eba-ac81-11ec-8b6b-0242ac110002 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:4823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f1b6c75a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:4823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:f1b6f3e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y3R4 biolink:molecularly_interacts_with DrugCentral:4823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peramivir targets Enzyme (Sialidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:f1b71fd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:D5F1R0 biolink:molecularly_interacts_with DrugCentral:4823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f1b74b4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:4823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f1b77448-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:4823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:f1b79cca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:4823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f1b7c57e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9IGQ6 biolink:molecularly_interacts_with DrugCentral:4823 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:f1b7ee28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4824 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etilefrine pivalate is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:f1b81308-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48357 biolink:molecularly_interacts_with DrugCentral:4826 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 metreleptin is agonist of Membrane receptor (Leptin receptor) DrugCentral uuid:f1b83784-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:4829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:f1b8602e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:4829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f1b888ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08493 biolink:molecularly_interacts_with DrugCentral:4829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:f1b8b3c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4829 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.131']} DrugCentral uuid:f1b8dc52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M3M2 biolink:molecularly_interacts_with DrugCentral:4830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.959']} DrugCentral uuid:f1b904d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0PJK1 biolink:molecularly_interacts_with DrugCentral:4830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:f1b92d6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.081']} DrugCentral uuid:f1b95646-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WWX8 biolink:molecularly_interacts_with DrugCentral:4830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 empagliflozin targets Transporter (Sodium/myo-inositol cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:f1b97f68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4830 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 empagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.244']} DrugCentral uuid:f1b9a830-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4832 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naloxegol is antagonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:f1b9cc98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4833 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemigliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.328']} DrugCentral uuid:f1b9f718-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4833 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemigliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:f1ba1fc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:4834 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eliglustat is inhibitor of Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.827']} DrugCentral uuid:f1ba4844-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:4836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afamelanotide targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f1ba70f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f1ba9d12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f1bac7b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:f1baf05a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33033 biolink:molecularly_interacts_with DrugCentral:4836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:f1bb1940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41149 biolink:molecularly_interacts_with DrugCentral:4836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:f1bb41d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56450 biolink:molecularly_interacts_with DrugCentral:4836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:f1bb6a44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01727 biolink:molecularly_interacts_with DrugCentral:4836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afamelanotide targets GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:f1bb92d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:4836 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 afamelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:f1bbbc06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:4839 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprotinin is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f1bbe4b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:4839 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aprotinin is inhibitor of Enzyme (Plasma kallikrein) DrugCentral uuid:f1bc0940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:4846 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ecallantide is inhibitor of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.602']} DrugCentral uuid:f1bc3208-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:4848 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatropin is agonist of GPCR (Growth hormone receptor) DrugCentral uuid:f1bc57ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:4853 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cridanimod targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:f1bc8082-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3TBT3 biolink:molecularly_interacts_with DrugCentral:4853 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cridanimod targets Unclassified (Stimulator of interferon genes protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f1bca936-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 conjugated estrogens is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:f1bccea2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4855 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 conjugated estrogens is agonist of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:f1bcf35a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:4857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone sulphate targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:f1bd1bf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:4857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone sulphate targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:f1bd4490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone sulphate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:f1bd6902-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4857 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estrone sulphate is agonist of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:f1bd8df6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q60748 biolink:molecularly_interacts_with DrugCentral:4858 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f1bdb68c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47866 biolink:molecularly_interacts_with DrugCentral:4858 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.9']} DrugCentral uuid:f1bddf04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13324 biolink:molecularly_interacts_with DrugCentral:4858 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f1be07a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34998 biolink:molecularly_interacts_with DrugCentral:4858 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.481']} DrugCentral uuid:f1be3544-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenibut is agonist of GPCR (GABA-B receptor) DrugCentral uuid:f1be3544-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4863 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 phenibut is agonist of GPCR (GABA-B receptor) DrugCentral uuid:f1be638e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f1be8c10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:f1beccd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f1beccd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f1beccd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f1beccd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f1beccd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f1beccd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f1beccd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f1bf3ac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.951']} DrugCentral uuid:f1bf640a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4864 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 levomilnacipran is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.035']} DrugCentral uuid:f1bf8cb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebanazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:f1bfb13a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4865 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mebanazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:f1bfd5ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f1bffed8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:f1c02868-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:f1c050d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:f1c07958-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f1c0a248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f1c0cad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f1c0f356-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f1c11be2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:f1c14504-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f1c16d86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f1c19608-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:f1c1be94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f1c1ea4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:f1c2131c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f1c23bb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:f1c26434-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f1c28d10-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:f1c2b59c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f1c2de28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:f1c3075e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:f1c32ffe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f1c3588a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:f1c3810c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:f1c3ab1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f1c3d404-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f1c3fc86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f1c4260c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f1c44ee8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f1c47774-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f1c49fec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41212 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Transcription factor (Transcription factor ETV6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f1c4c88c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:f1c4f244-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:f1c51bde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.155']} DrugCentral uuid:f1c54474-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:f1c56d1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4866 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ceritinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:f1c598fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f1c5c1ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f1c5ea5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f1c61372-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:f1c63c30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f1c664d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:f1c68d7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:f1c6b6a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:f1c6df50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f1c707fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:f1c7346e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:f1c7346e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4867 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dexrabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:f1c76470-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25116 biolink:molecularly_interacts_with DrugCentral:4870 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vorapaxar is antagonist of GPCR (Proteinase-activated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.092']} DrugCentral uuid:f1c78d06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tedizolid phosphate targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f1c7b592-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4873 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tedizolid phosphate targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:f1c7de28-ac81-11ec-8b6b-0242ac110002 UniProtKB:F2SHH3 biolink:molecularly_interacts_with DrugCentral:4874 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efinaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:f1c803da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daclatasvir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:f1c82c84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daclatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.64']} DrugCentral uuid:f1c8551a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daclatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.64']} DrugCentral uuid:f1c87db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daclatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.046']} DrugCentral uuid:f1c8a6dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4875 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daclatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.301']} DrugCentral uuid:f1c8cf86-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:f1c8f83a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:f1c921f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:f1c94aec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f1c973a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f1c99cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:f1c9c5e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:f1c9ee98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:f1ca1738-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:f1ca3fe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.67']} DrugCentral uuid:f1ca6904-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:f1ca91a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:f1caba30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4876 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.569']} DrugCentral uuid:f1cae3d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f1cb0f76-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f1cb3b68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:4877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f1cb6412-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:4877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:f1cb8cbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26637 biolink:molecularly_interacts_with DrugCentral:4877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tavaborole targets Enzyme (Leucine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:f1cbb5c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:F2SF18 biolink:molecularly_interacts_with DrugCentral:4877 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tavaborole is inhibitor of Enzyme (Leucine-tRNA ligase) DrugCentral uuid:f1cbda1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:4878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idelalisib targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f1cc03c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NEB9 biolink:molecularly_interacts_with DrugCentral:4878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 3-kinase catalytic subunit type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f1cc2d2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:4878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.086']} DrugCentral uuid:f1cc55c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:4878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.248']} DrugCentral uuid:f1cc7e4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:4878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.051']} DrugCentral uuid:f1cca6ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4878 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 idelalisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.602']} DrugCentral uuid:f1ccd0d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:4879 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enoxaparin sodium is activator of Secreted (Antithrombin-III) DrugCentral uuid:f1ccf610-ac81-11ec-8b6b-0242ac110002 UniProtKB:P58308 biolink:molecularly_interacts_with DrugCentral:4881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suvorexant targets GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:f1cd1ec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P58307 biolink:molecularly_interacts_with DrugCentral:4881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suvorexant targets GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f1cd4782-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:4881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suvorexant is antagonist of GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:f1cd707c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43614 biolink:molecularly_interacts_with DrugCentral:4881 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 suvorexant is antagonist of GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:f1cd9926-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 istradefylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:f1cdc1c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 istradefylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f1cdea5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 istradefylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:f1ce139c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 istradefylline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:f1ce3caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 istradefylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f1ce6536-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 istradefylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f1ce8dcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 istradefylline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:f1ceb982-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4882 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 istradefylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:f1cee48e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4885 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dulaglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) DrugCentral uuid:f1cf0900-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16233 biolink:molecularly_interacts_with DrugCentral:4886 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetilistat is inhibitor of Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.225']} DrugCentral uuid:f1cf3196-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:4888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiroxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:f1cf5ac2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:4888 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 topiroxostat is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.276']} DrugCentral uuid:f1cf834e-ac81-11ec-8b6b-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:4889 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asunaprevir targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:f1cfabda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4889 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 asunaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:f1cfd52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:4890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:f1cffed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8C3K6 biolink:molecularly_interacts_with DrugCentral:4890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:f1d02786-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53790 biolink:molecularly_interacts_with DrugCentral:4890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:f1d05026-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q923I7 biolink:molecularly_interacts_with DrugCentral:4890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:f1d07a06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipragliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.727']} DrugCentral uuid:f1d0a42c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4890 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.132']} DrugCentral uuid:f1d0cdf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4891 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 luseogliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.399']} DrugCentral uuid:f1d0f698-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4891 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 luseogliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.646']} DrugCentral uuid:f1d11f74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4892 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofogliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.073']} DrugCentral uuid:f1d1481e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4892 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tofogliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.538']} DrugCentral uuid:f1d17096-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07650 biolink:molecularly_interacts_with DrugCentral:4893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tipiracil targets Enzyme (Thymidine phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f1d1994a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19971 biolink:molecularly_interacts_with DrugCentral:4893 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tipiracil is inhibitor of Enzyme (Thymidine phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:f1d1c28a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:4894 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 iguratimod targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f1d1eb16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14740 biolink:molecularly_interacts_with DrugCentral:4895 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.54']} DrugCentral uuid:f1d2137a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4895 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.585']} DrugCentral uuid:f1d23c06-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4895 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.268']} DrugCentral uuid:f1d267ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4895 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teneligliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.432']} DrugCentral uuid:f1d290d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:4896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:f1d2b942-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.167']} DrugCentral uuid:f1d2e21e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:f1d30aa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4896 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:f1d333cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4897 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 edoxaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.252']} DrugCentral uuid:f1d35c80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4898 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 netupitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.022']} DrugCentral uuid:f1d385b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4899 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ledipasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:f1d3ae2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4899 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ledipasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:f1d3d6ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4899 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ledipasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:f1d40040-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4899 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ledipasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.509']} DrugCentral uuid:f1d42a20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:4900 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diquafosol is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f1d452a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:4900 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 diquafosol is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.469']} DrugCentral uuid:f1d47b38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4901 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 insulin glargine is agonist of Kinase (Insulin receptor) DrugCentral uuid:f1d49f8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4902 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imidafenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['8.384']} DrugCentral uuid:f1d4c89a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4902 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imidafenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['9.499']} DrugCentral uuid:f1d4f13a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:f1d519da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:f1d54266-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:f1d56bb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f1d5945a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:f1d5bcf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:f1d5e572-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f1d60ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.21']} DrugCentral uuid:f1d6373e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f1d65fd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:f1d68856-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f1d6b290-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.38']} DrugCentral uuid:f1d6db12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.02']} DrugCentral uuid:f1d703a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:f1d72d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:f1d755ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f1d77e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f1d7a6e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:f1d7d120-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f1d7fad8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:f1d8236e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f1d84c04-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:f1d87508-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:f1d89dd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f1d8c666-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f1d8ef88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f1d918be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:f1d94168-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f1d969f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f1d99294-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:f1d9bc24-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f1d9e4c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f1da0d3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f1da3654-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:f1da5eea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f1da878a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f1dab00c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:f1dad94c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:f1db01ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:f1db2a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f1db532c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f1db7d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f1dba61a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:f1dbcec4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f1dbf82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:f1dc2126-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f1dc49c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:f1dc725c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:f1dc9b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f1dcc5ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f1dcee58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:f1dd16f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:f1dd3f98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f1dd6bf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:f1dd963c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:f1ddbee6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f1dde7ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f1de1058-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:f1de38c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:f1de6166-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.66']} DrugCentral uuid:f1de8a9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f1deb33c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:f1dedbb4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f1df044a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f1df2f38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:f1df580a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:f1df8096-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f1dfa92c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:f1dfd28a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:f1dffc24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f1e024a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f1e04dd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.29']} DrugCentral uuid:f1e0767c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:f1e09f1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f1e0c79e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:f1e0f1a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:f1e11c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f1e14552-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f1e16dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f1e196c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f1e1bf64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:f1e1e7fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f1e21086-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:f1e239c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f1e2625c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:f1e28af2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:f1e2b4aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f1e2e074-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:f1e30c2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49840 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Glycogen synthase kinase-3 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:f1e33510-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:f1e35e14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f1e386be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:f1e3af36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:f1e3d7c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f1e401f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f1e42a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f1e4531e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f1e47bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:f1e4a558-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:f1e4cde4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f1e4f670-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:f1e51f10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f1e5480a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:f1e570aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f1e59936-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f1e5c1cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f1e5eaf8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:f1e613ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f1e63c42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:f1e664f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f1e69110-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:f1e6b9a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f1e6e250-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:f1e70b72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:f1e733ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f1e75c9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f1e7852a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:f1e7ae42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f1e7d6ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f1e8005e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f1e82908-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f1e852ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f1e87b56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:f1e8a3f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f1e8cdae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.31']} DrugCentral uuid:f1e8f720-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:f1e91fc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f1e94860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:f1e970e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f1e99ed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:f1e9ca2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f1e9f2c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:f1ea1ca4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:f1ea45bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f1ea6e3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:f1ea96d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:f1eabfba-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:f1eae846-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f1eb10be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f1eb394a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:f1eb6280-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f1eb8b16-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f1ebb38e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f1ebdd1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:f1ec0802-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f1ec30a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:f1ec5924-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f1ec81b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f1ecaa96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f1ecd34a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f1ecfbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.07']} DrugCentral uuid:f1ed250c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16566 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f1ed4e38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f1ed76ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f1ed9f64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:f1edc8cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f1edf158-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f1ee19ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:f1ee427a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f1ee6b6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f1ee940a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f1eebdc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f1eee662-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f1ef0fac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f1ef384c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f1ef60f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f1ef8996-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f1efb308-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f1efdc98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f1f00542-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f1f02e46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f1f056e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f1f07f68-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f1f0a7ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f1f0d134-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:f1f0f9d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f1f12260-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f1f14ae2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f1f17530-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f1f1a0aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f1f1cc38-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f1f1f65e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f1f21f58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f1f247e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f1f27070-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f1f298fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f1f2c25a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f1f2eaf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f1f31372-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:f1f33d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f1f3671e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f1f38fa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:f1f3b82c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:f1f3e22a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f1f40b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f1f433d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f1f45c50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f1f48590-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:f1f4ae12-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f1f4d7e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f1f5007e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:f1f52ae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.28']} DrugCentral uuid:f1f55358-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f1f57bee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f1f5a470-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:f1f5cd9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f1f5f628-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f1f61ebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f1f647d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:f1f67076-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f1f698f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f1f6c198-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.74']} DrugCentral uuid:f1f6eb6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f1f71742-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:f1f7401e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f1f768aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f1f7919a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:f1f7bb20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f1f7e3b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:f1f80c60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.983']} DrugCentral uuid:f1f83564-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:f1f85e04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:f1f88690-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:f1f8af30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4903 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:f1f8daf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4904 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 adalimumab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:f1f90228-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4905 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pegaptanib is antagonist of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:f1f926d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:4906 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fimasartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.377']} DrugCentral uuid:f1f94f80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:f1f978de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:f1f9a200-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:f1f9cabe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f1f9f3d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:f1fa1c76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2NL67 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib targets Unclassified (Poly [ADP-ribose] polymerase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f1fa4516-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N5Y8 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib targets Unclassified (Mono [ADP-ribose] polymerase PARP16) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:f1fa6dac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib targets Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:f1fa9796-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f1fac1a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:f1faea5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:4907 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:f1fb12fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4908 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acotiamide is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:f1fb3c82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31358 biolink:molecularly_interacts_with DrugCentral:4909 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alemtuzumab is antibody binding of Surface antigen (CAMPATH-1 antigen) DrugCentral uuid:f1fb611c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4910 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 felypressin is agonist of GPCR (Vasopressin V1a receptor) DrugCentral uuid:f1fb8598-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ombitasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.85']} DrugCentral uuid:f1fbae42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WMX2 biolink:molecularly_interacts_with DrugCentral:4912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ombitasvir targets Unclassified (Genome polyprotein [Cleaved into: Core protein p21) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.92']} DrugCentral uuid:f1fbd8b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ombitasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.301']} DrugCentral uuid:f1fc014e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4912 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ombitasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.854']} DrugCentral uuid:f1fc29da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4914 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasabuvir targets Enzyme (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:f1fc5266-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4914 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasabuvir targets Unclassified (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:f1fc7d54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:4915 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 blinatumomab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:f1fcadba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f1fcadba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f1fcadba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f1fced2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aflibercept is inhibitor of Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['12.301']} DrugCentral uuid:f1fd16b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49763 biolink:molecularly_interacts_with DrugCentral:4916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aflibercept is inhibitor of Secreted (Placenta growth factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.409']} DrugCentral uuid:f1fd3f64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49765 biolink:molecularly_interacts_with DrugCentral:4916 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aflibercept is inhibitor of Secreted (Vascular endothelial growth factor B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.717']} DrugCentral uuid:f1fd6804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4917 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ramucirumab is antibody binding of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:f1fd90c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:4921 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 safinamide targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:f1fdb99e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4921 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 safinamide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:f1fde234-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4921 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 safinamide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.71']} DrugCentral uuid:f1fe0b88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:4921 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 safinamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:f1fe3db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:f1fe3db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:f1fe3db0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:f1fe7ffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4921 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 safinamide is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:f1fea8b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:4923 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 nivolumab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.14']} DrugCentral uuid:f1fed194-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:4924 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pembrolizumab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:f1fefeb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 becaplermin is agonist of Kinase (Platelet-derived growth factor receptor) DrugCentral uuid:f1fefeb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4925 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 becaplermin is agonist of Kinase (Platelet-derived growth factor receptor) DrugCentral uuid:f1ff2d1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32301 biolink:molecularly_interacts_with DrugCentral:4927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albiglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f1ff570e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4927 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 albiglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:f1ff801c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23945 biolink:molecularly_interacts_with DrugCentral:4928 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 follitropin is agonist of GPCR (Follicle-stimulating hormone receptor) DrugCentral uuid:f1ffa4c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:4929 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lutropin alfa is agonist of GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.9']} DrugCentral uuid:f1ffcd6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16473 biolink:molecularly_interacts_with DrugCentral:4930 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 thyrotropin alfa is agonist of GPCR (Thyrotropin receptor) DrugCentral uuid:f1fff1dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corticotropin is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:f2001c7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corticotropin is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:f2004812-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:4931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corticotropin is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:f20070d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corticotropin is agonist of GPCR (Adrenocorticotropic hormone receptor) DrugCentral uuid:f2009560-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q64326 biolink:molecularly_interacts_with DrugCentral:4931 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corticotropin is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.8']} DrugCentral uuid:f200c260-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:4933 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocilizumab is antibody binding of Membrane receptor (Interleukin-6 receptor) DrugCentral uuid:f200c260-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:4933 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tocilizumab is antibody binding of Membrane receptor (Interleukin-6 receptor) DrugCentral uuid:f200f0f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16552 biolink:molecularly_interacts_with DrugCentral:4934 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 secukinumab is antibody binding of Cytokine (Interleukin-17A) DrugCentral uuid:f201156c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03420 biolink:molecularly_interacts_with DrugCentral:4935 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palivizumab is antibody binding of Surface antigen (Fusion glycoprotein F0) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.357']} DrugCentral uuid:f2013e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:4936 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 parathyroid hormone is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) DrugCentral uuid:f2016364-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alectinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f2018bf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alectinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:f201b490-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alectinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f201dd44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alectinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:f202071a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alectinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.721']} DrugCentral uuid:f2022ff6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4937 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alectinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.319']} DrugCentral uuid:f202588c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:4938 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripasudil is inhibitor of Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f20281b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4938 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripasudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.292']} DrugCentral uuid:f202aa58-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4938 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripasudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.721']} DrugCentral uuid:f202d2e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vaniprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:f202fbe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vaniprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:f2032528-ac81-11ec-8b6b-0242ac110002 UniProtKB:K7XJL6 biolink:molecularly_interacts_with DrugCentral:4939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vaniprevir targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:f2034ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vaniprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.301']} DrugCentral uuid:f2037794-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99IB8 biolink:molecularly_interacts_with DrugCentral:4939 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vaniprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:f203a048-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01589 biolink:molecularly_interacts_with DrugCentral:4940 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 basiliximab is antibody binding of Membrane receptor (Interleukin-2 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:f203cb22-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:f203f3ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:f2041c44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f20448d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f20448d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f2048102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib targets Kinase (CDK2/Cyclin A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f2048102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib targets Kinase (CDK2/Cyclin A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f204b8c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib targets Kinase (CDK6/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:f204b8c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib targets Kinase (CDK6/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:f204ed36-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib is inhibitor of Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.097']} DrugCentral uuid:f20515d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib is inhibitor of Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:f2053e76-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:f2056702-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4941 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 palbociclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:f20590ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:f205ba72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:f205e330-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.409']} DrugCentral uuid:f2060bd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:f20634ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f2065d6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f206860a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.658']} DrugCentral uuid:f206aeaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.398']} DrugCentral uuid:f206d7fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:f2070198-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.292']} DrugCentral uuid:f2072a4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4942 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenvatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:f20752e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4943 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arformoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:f2077e66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4943 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arformoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:f207a9ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4943 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arformoterol is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.947']} DrugCentral uuid:f207d258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4943 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 arformoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.538']} DrugCentral uuid:f207fb70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:4945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancreozymin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10']} DrugCentral uuid:f20823d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:4945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancreozymin is agonist of GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f2084c56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:4945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancreozymin is agonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f20874f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:4945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancreozymin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:f2089e40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancreozymin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f208c6cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63931 biolink:molecularly_interacts_with DrugCentral:4945 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pancreozymin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:f208ef6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:4946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avibactam targets Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f209182a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:4946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avibactam targets Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f209428c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:4946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.155']} DrugCentral uuid:f2096e74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:4946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f20998ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:4946 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.699']} DrugCentral uuid:f209c16c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y275 biolink:molecularly_interacts_with DrugCentral:4949 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belimumab is antibody binding of Cytokine (Tumor necrosis factor ligand superfamily member 13B) DrugCentral uuid:f209ea48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:4950 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abciximab is antibody binding of Adhesion (Integrin alpha-IIb/beta-3) DrugCentral uuid:f209ea48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:4950 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abciximab is antibody binding of Adhesion (Integrin alpha-IIb/beta-3) DrugCentral uuid:f20a18ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4951 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ofatumumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.92']} DrugCentral uuid:f20a416e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01584 biolink:molecularly_interacts_with DrugCentral:4952 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 canakinumab is antibody binding of Cytokine (Interleukin-1 beta) DrugCentral uuid:f20a6e64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:f20a6e64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:f20a6e64-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:f20aad70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4954 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cetuximab is antibody binding of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.41']} DrugCentral uuid:f20ad700-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4955 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 panitumumab is agonist of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:f20affaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4956 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bevacizumab is antibody binding of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:f20b261a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4957 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pertuzumab is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:f20b4a82-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16410 biolink:molecularly_interacts_with DrugCentral:4958 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ipilimumab is antibody binding of Surface antigen (Cytotoxic T-lymphocyte protein 4) DrugCentral uuid:f20b7034-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20701 biolink:molecularly_interacts_with DrugCentral:4959 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 efalizumab is antibody binding of Adhesion (Leukocyte adhesion glycoprotein LFA-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.4']} DrugCentral uuid:f20b98e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4960 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 insulin degludec is agonist of Kinase (Insulin receptor) DrugCentral uuid:f20bbdd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13423 biolink:molecularly_interacts_with DrugCentral:4961 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 raxibacumab is antibody binding of Secreted (Protective antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.556']} DrugCentral uuid:f20be712-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28908 biolink:molecularly_interacts_with DrugCentral:4964 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brentuximab vedotin is binding agent of Membrane receptor (Tumor necrosis factor receptor superfamily member 8) DrugCentral uuid:f20c2a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f20c2a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f20c2a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f20c2a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f20c2a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f20c2a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f20c2a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f20c2a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f20c2a92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f20c9ec8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14788 biolink:molecularly_interacts_with DrugCentral:4965 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 denosumab is antibody binding of Cytokine (Tumor necrosis factor ligand superfamily member 11) DrugCentral uuid:f20cc72c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29460 biolink:molecularly_interacts_with DrugCentral:4966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-12) DrugCentral uuid:f20cc72c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29460 biolink:molecularly_interacts_with DrugCentral:4966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-12) DrugCentral uuid:f20cfb7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:4966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:f20cfb7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:4966 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:f20d29f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4967 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 golimumab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:f20d4e68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4968 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 certolizumab pegol is antibody binding of Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.046']} DrugCentral uuid:f20d7712-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:4969 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eculizumab is antibody binding of Secreted (Complement C5) DrugCentral uuid:f20d9fbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05556 biolink:molecularly_interacts_with DrugCentral:4970 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-1) DrugCentral uuid:f20d9fbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05556 biolink:molecularly_interacts_with DrugCentral:4970 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-1) DrugCentral uuid:f20dd220-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4970 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) DrugCentral uuid:f20dd220-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4970 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) DrugCentral uuid:f20e00b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4971 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ranibizumab is antibody binding of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:f20e25fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01854 biolink:molecularly_interacts_with DrugCentral:4972 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omalizumab is antibody binding of Antibody (Ig epsilon chain C region) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.16']} DrugCentral uuid:f20e4f8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:4973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chidamide targets Enzyme (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f20e7824-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:4973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chidamide targets Cytokine (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f20ea0ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.135']} DrugCentral uuid:f20ecbd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.365']} DrugCentral uuid:f20ef754-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:f20f227e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.022']} DrugCentral uuid:f20f4b00-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:f20f73e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4973 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.108']} DrugCentral uuid:f20f9c7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4974 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infliximab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:f20fc10c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4975 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rituximab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:f20fec04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4976 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 triamcinolone hexacetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:f2101094-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:4977 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 siltuximab is antibody binding of Cytokine (Interleukin-6) DrugCentral uuid:f21034e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4978 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etanercept is inhibitor of Cytokine (Tumor necrosis factor) DrugCentral uuid:f2105978-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4979 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:f2107dea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20138 biolink:molecularly_interacts_with DrugCentral:4980 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gemtuzumab ozogamicin is antibody binding of Surface antigen (Myeloid cell surface antigen CD33) DrugCentral uuid:f210a3a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4981 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 insulin aspart is agonist of Kinase (Insulin receptor) DrugCentral uuid:f210cbec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vedolizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f210cbec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4982 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vedolizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f210ffea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4983 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 obinutuzumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) DrugCentral uuid:f21124e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4984 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibritumomab tiuxetan is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.854']} DrugCentral uuid:f2114d9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4985 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 insulin detemir is agonist of Kinase (Insulin receptor) DrugCentral uuid:f211720e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4986 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pegfilgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:f211969e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4987 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:f211baf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:4988 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deoxycholic acid is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:f211e446-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:4988 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deoxycholic acid targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:f2120caa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:4988 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deoxycholic acid is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:f21234fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07445 biolink:molecularly_interacts_with DrugCentral:4988 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deoxycholic acid targets Unclassified (Steroid Delta-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f2125f84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab emtansine is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:f212a6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f212a6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f212a6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f212a6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f212a6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f212a6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f212a6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f212a6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f212a6e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f21319ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4991 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lipegfilgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:f213423c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4993 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vonoprazan is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:f213423c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4993 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vonoprazan is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:f2137630-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:4995 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epoetin alfa is agonist of Membrane receptor (Erythropoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11.15']} DrugCentral uuid:f2139f66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:4996 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romiplostim is agonist of Membrane receptor (Thrombopoietin receptor) DrugCentral uuid:f213c400-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NBP7 biolink:molecularly_interacts_with DrugCentral:5000 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 evolocumab is inhibitor of Enzyme (Proprotein convertase subtilisin/kexin type 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.72']} DrugCentral uuid:f213ec78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:5001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eluxadoline targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:f214150e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:5001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eluxadoline targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:f2144038-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:5001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eluxadoline is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:f2146d24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:5001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eluxadoline is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:f21495ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eluxadoline is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f214bea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5001 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eluxadoline is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:f214e7e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5002 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 insulin lispro is agonist of Kinase (Insulin receptor) DrugCentral uuid:f2150c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5003 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 insulin human targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:f21534ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15127 biolink:molecularly_interacts_with DrugCentral:5003 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 insulin human targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.71']} DrugCentral uuid:f2155d38-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5003 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 insulin human is agonist of Kinase (Insulin receptor) DrugCentral uuid:f215825e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:5005 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mirodenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.469']} DrugCentral uuid:f215aae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:5006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cangrelor is antagonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f215d45c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6NS65 biolink:molecularly_interacts_with DrugCentral:5006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cangrelor is antagonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:f215fd06-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:5006 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cangrelor is antagonist of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.627']} DrugCentral uuid:f216266e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5007 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epoetin theta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:f2164ae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q62226 biolink:molecularly_interacts_with DrugCentral:5008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sonidegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:f2167362-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5008 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sonidegib is antagonist of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.222']} DrugCentral uuid:f2169c02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5009 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecasermin targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:f216c51a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5009 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mecasermin is agonist of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:f216edc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5010 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumacaftor is pharmacological chaperone of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.456']} DrugCentral uuid:f2171e0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:f2171e0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:f2171e0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:f217570a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:5012 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sacubitril is inhibitor of Enzyme (Neprilysin) DrugCentral uuid:f2177b7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5013 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trelagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.398']} DrugCentral uuid:f217a48a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f217cd3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:f217f98a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:f21825ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:f2184ec6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:f21877f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:f218a092-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:f218c928-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:f218f1be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:f2191aea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.857']} DrugCentral uuid:f2194376-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.721']} DrugCentral uuid:f2196c02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:f2199484-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:f219bfd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:f219e876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:f21a121a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f21a3ace-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:f21a63e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:f21a8c86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:f21ab526-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:f21addda-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.025']} DrugCentral uuid:f21b071a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.201']} DrugCentral uuid:f21b2fc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:f21b586e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:f21b80fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:f21baab2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.523']} DrugCentral uuid:f21bd35c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.921']} DrugCentral uuid:f21bfbfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5014 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.328']} DrugCentral uuid:f21c2528-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5015 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pegvisomant is antagonist of GPCR (Growth hormone receptor) DrugCentral uuid:f21c499a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NBP7 biolink:molecularly_interacts_with DrugCentral:5016 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alirocumab is inhibitor of Enzyme (Proprotein convertase subtilisin/kexin type 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:f21c7622-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPH3 biolink:molecularly_interacts_with DrugCentral:5017 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anakinra is antagonist of Membrane receptor (Interleukin-1 receptor, type I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f21c7622-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPH3 biolink:molecularly_interacts_with DrugCentral:5017 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 anakinra is antagonist of Membrane receptor (Interleukin-1 receptor, type I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f21caa2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flibanserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.93']} DrugCentral uuid:f21cd37e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flibanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.516']} DrugCentral uuid:f21cfc28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flibanserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:f21d24c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flibanserin is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:f21d4d86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.049']} DrugCentral uuid:f21d796e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.054']} DrugCentral uuid:f21da376-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:5022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flibanserin targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.093']} DrugCentral uuid:f21dcc34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flibanserin is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:f21df5f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5022 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:f21e229c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5025 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sargramostim is agonist of Membrane receptor (Granulocyte macrophage colony-stimulating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.301']} DrugCentral uuid:f21e229c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5025 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sargramostim is agonist of Membrane receptor (Granulocyte macrophage colony-stimulating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.301']} DrugCentral uuid:f21e5aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5026 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oprelvekin is agonist of Membrane receptor (Interleukin-11 receptor) DrugCentral uuid:f21e5aaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5026 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oprelvekin is agonist of Membrane receptor (Interleukin-11 receptor) DrugCentral uuid:f21e8930-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:5027 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rolapitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:f21eb28e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:5031 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mogamulizumab is antibody binding of GPCR (C-C chemokine receptor type 4) DrugCentral uuid:f21ed6f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f21effbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:f21f2840-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f21f5360-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f21f7c0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f21fa5a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f21fced0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:f21ff784-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:f2202042-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:f22048e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine is partial agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.07']} DrugCentral uuid:f220722c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:f2209ae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f220c394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:f220ec34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:f2211704-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5037 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:f2214256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.48']} DrugCentral uuid:f2216aec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.12']} DrugCentral uuid:f2219472-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:f221bd6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f221e5e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f2220e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f2223710-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f2226032-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:f22288be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:f222b136-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:f222db16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f22303fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f2232c7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f223556e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f2237e54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:f223a6cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:f223cf76-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6XA80 biolink:molecularly_interacts_with DrugCentral:5039 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tannic acid targets Unclassified (Leukotriene C4 synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f223f7f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5042 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somatrem is agonist of GPCR (Growth hormone receptor) DrugCentral uuid:f2241d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5044 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:f224417c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cobimetinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:f2246a08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cobimetinib is allosteric modulator of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f224929e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5046 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cobimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:f224bd46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5047 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saroglitazar is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.187']} DrugCentral uuid:f224e5f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5047 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 saroglitazar is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:f2250e7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f22536fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:f2256002-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f2258974-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f225b336-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f225dbcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P58406 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f2260516-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:f2262dc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f2265656-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f2267f82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:f226ab1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:5048 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pitolisant is inverse agonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.796']} DrugCentral uuid:f226d428-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f226fcc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:f22725b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f2274e58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f22776f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f2279fac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f227c8f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f227f1a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:f2281a40-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:f22842e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:f2286cf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:f228959c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:f228be3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.469']} DrugCentral uuid:f228e70e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f229109e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5052 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 aripiprazole lauroxil is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.469']} DrugCentral uuid:f229393e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omarigliptin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:f22961ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28843 biolink:molecularly_interacts_with DrugCentral:5054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omarigliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:f2298bfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5054 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omarigliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:f229b4b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5057 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 insulin glulisine is agonist of Kinase (Insulin receptor) DrugCentral uuid:f229d948-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:5059 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lusutrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.076']} DrugCentral uuid:f22a01b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5060 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esflurbiprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f22a2b0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:5060 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 esflurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f22a53be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:5061 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mepolizumab is antibody binding of Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:f22a7c5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5062 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osimertinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:f22aa4d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5062 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osimertinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f22acdd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5062 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osimertinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:f22af65c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5062 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osimertinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:f22b1ed4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53634 biolink:molecularly_interacts_with DrugCentral:5062 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osimertinib targets Enzyme (Dipeptidyl peptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:f22b476a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5062 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osimertinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:f22b71f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5062 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osimertinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:f22b9a94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:5063 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daratumumab is antibody binding of Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:f22bc38e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:5064 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 climbazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f22bebfc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5065 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trenbolone hexahydrobenzylcarbonate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:f22c1726-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:5065 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trenbolone hexahydrobenzylcarbonate targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:f22c42fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5066 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenecteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:f22c6a46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:5067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.509']} DrugCentral uuid:f22c9304-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:5067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:f22cbc08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:5067 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:f22ce49e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02563 biolink:molecularly_interacts_with DrugCentral:5068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brivaracetam is inhibitor of Unclassified (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f22d0d3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L0J3 biolink:molecularly_interacts_with DrugCentral:5068 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brivaracetam is modulator of Transporter (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f22d3688-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5071 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 necitumumab is antibody binding of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.49']} DrugCentral uuid:f22d5f64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NQ25 biolink:molecularly_interacts_with DrugCentral:5072 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elotuzumab is antibody binding of Membrane receptor (SLAM family member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:f22d8908-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:5075 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lesinurad is inhibitor of Transporter (Solute carrier family 22 member 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.432']} DrugCentral uuid:f22db220-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:5075 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lesinurad is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.137']} DrugCentral uuid:f22ddbec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5077 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f22e0680-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:5077 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:f22e2f0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:5077 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selexipag targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f22e5784-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:5077 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selexipag is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f22e8088-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:5077 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:f22ea914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5077 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f22ed1b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:5077 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selexipag is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:f22efa5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5078 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lobeglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:f22f2380-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5078 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lobeglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:f22f4c02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elbasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:f22f7448-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elbasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:f22f9cf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.523']} DrugCentral uuid:f22fc8da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:f22ff1e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5080 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.523']} DrugCentral uuid:f2301a4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:5081 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grazoprevir targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:f2304332-ac81-11ec-8b6b-0242ac110002 UniProtKB:K7XJL6 biolink:molecularly_interacts_with DrugCentral:5081 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grazoprevir targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:f2306bbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q0ZMF1 biolink:molecularly_interacts_with DrugCentral:5081 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grazoprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:f2309468-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5081 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.301']} DrugCentral uuid:f230bcea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5081 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.398']} DrugCentral uuid:f230e648-ac81-11ec-8b6b-0242ac110002 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5081 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.523']} DrugCentral uuid:f2310eca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16552 biolink:molecularly_interacts_with DrugCentral:5083 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ixekizumab is antibody binding of Cytokine (Interleukin-17A) DrugCentral uuid:f2313b20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:f2313b20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:f2313b20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:f23175a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06729 biolink:molecularly_interacts_with DrugCentral:5088 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alefacept is inhibitor of Surface antigen (T-cell surface antigen CD2) DrugCentral uuid:f2319d68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33681 biolink:molecularly_interacts_with DrugCentral:5089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD80) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f231c644-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42081 biolink:molecularly_interacts_with DrugCentral:5089 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD86) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f231eef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33681 biolink:molecularly_interacts_with DrugCentral:5091 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD80) DrugCentral uuid:f232136a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42081 biolink:molecularly_interacts_with DrugCentral:5091 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD86) DrugCentral uuid:f23238f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:5093 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 reslizumab is antibody binding of Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.092']} DrugCentral uuid:f232619e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13423 biolink:molecularly_interacts_with DrugCentral:5094 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 obiltoxaximab is antibody binding of Secreted (Protective antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.481']} DrugCentral uuid:f2328a52-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01583 biolink:molecularly_interacts_with DrugCentral:5105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilonacept is inhibitor of Cytokine (Interleukin-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.854']} DrugCentral uuid:f232b2fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18510 biolink:molecularly_interacts_with DrugCentral:5105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilonacept is inhibitor of Unclassified (Interleukin-1 receptor antagonist protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.215']} DrugCentral uuid:f232dc3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01584 biolink:molecularly_interacts_with DrugCentral:5105 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rilonacept is inhibitor of Cytokine (Interleukin-1 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['12.301']} DrugCentral uuid:f23304c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5109 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 urokinase is activator of Enzyme (Plasminogen) DrugCentral uuid:f233291c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f2335298-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:f2337b56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HCG7 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:f233a3a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f233cc32-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35573 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f233f504-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09848 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:f2341d7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16278 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:f23445e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59750 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:f2346e62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02401 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:f234975c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UUZ4 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Alpha-galactosidase C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:f234bfc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q42656 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Alpha-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f234e82e-ac81-11ec-8b6b-0242ac110002 UniProtKB:D3ZUM4 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:f23510ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8VNN2 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:f2353a7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06280 biolink:molecularly_interacts_with DrugCentral:5110 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 migalastat is pharmacological chaperone of Enzyme (Alpha-galactosidase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f2356448-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chromic chloride targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:f2358cca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5118 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 chromic chloride targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:f235b56a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:5133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venetoclax is inhibitor of Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:f235de6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92843 biolink:molecularly_interacts_with DrugCentral:5133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venetoclax is inhibitor of Cytosolic other (Apoptosis regulator Bcl-W) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:f2360736-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:5133 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 venetoclax is inhibitor of Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:f23633d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peginterferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f23633d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5137 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peginterferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f23666e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5139 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 interferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f23666e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5139 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 interferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f2369930-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5140 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 interferon beta-1b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f2369930-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5140 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 interferon beta-1b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f236c8ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5141 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:f236ed54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimavanserin is inverse agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f2371900-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5142 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pimavanserin is inverse agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f23741c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:5143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f2376a54-ac81-11ec-8b6b-0242ac110002 UniProtKB:O88587 biolink:molecularly_interacts_with DrugCentral:5143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f23792ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:5143 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:f237bbda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:5144 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gluconolactone targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:f237e47a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:5149 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 choriogonadotropin alfa is agonist of GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:f238090a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5151 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atezolizumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.39']} DrugCentral uuid:f238322c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velpatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:f2385b58-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velpatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:f23883ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.796']} DrugCentral uuid:f238ac70-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.854']} DrugCentral uuid:f238d664-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99IB8 biolink:molecularly_interacts_with DrugCentral:5154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.979']} DrugCentral uuid:f239021a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.046']} DrugCentral uuid:f2392e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q81495 biolink:molecularly_interacts_with DrugCentral:5154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:f23956ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9DHD6 biolink:molecularly_interacts_with DrugCentral:5154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:f2397fba-ac81-11ec-8b6b-0242ac110002 UniProtKB:O91936 biolink:molecularly_interacts_with DrugCentral:5154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.426']} DrugCentral uuid:f239a864-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5I2N3 biolink:molecularly_interacts_with DrugCentral:5154 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.097']} DrugCentral uuid:f239d0e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:5155 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 obeticholic acid targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f239f972-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:5155 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 obeticholic acid is agonist of Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.004']} DrugCentral uuid:f23a22a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5157 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darbepoetin alfa is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:f23a4b16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peginterferon alfa-2a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f23a4b16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5158 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peginterferon alfa-2a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f23a7988-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5160 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epoetin beta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:f23aa200-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peginterferon alfa-2b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f23aa200-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5164 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 peginterferon alfa-2b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f23ad32e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5165 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 methoxy polyethylene glycol-epoetin beta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:f23af7aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:5167 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lenograstim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:f23b1c6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:5169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eldecalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:f23b4160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:5169 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eldecalcitol is agonist of Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:f23b6a00-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5170 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 epoetin zeta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:f23b8e68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05362 biolink:molecularly_interacts_with DrugCentral:5174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lifitegrast targets Unclassified (Intercellular adhesion molecule 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:f23bbaf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05107 biolink:molecularly_interacts_with DrugCentral:5174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lifitegrast is antagonist of Adhesion (Integrin alpha-L/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:f23bbaf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05107 biolink:molecularly_interacts_with DrugCentral:5174 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lifitegrast is antagonist of Adhesion (Integrin alpha-L/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:f23bf75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:f23bf75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:f23bf75e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:f23c34bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NAC3 biolink:molecularly_interacts_with DrugCentral:5179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brodalumab is antibody binding of Membrane receptor (Interleukin-17 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:f23c34bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NAC3 biolink:molecularly_interacts_with DrugCentral:5179 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brodalumab is antibody binding of Membrane receptor (Interleukin-17 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:f23c68c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:5181 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etelcalcetide is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:f23c92ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5182 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eteplirsen is binding agent of RNA (exon 51 of dystrophin pre-mRNA) DrugCentral uuid:f23cb86a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5183 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olaratumab is antibody binding of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.4']} DrugCentral uuid:f23ce10a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5185 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallium (68Ga) edotreotide is antagonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:f23d0a36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18177 biolink:molecularly_interacts_with DrugCentral:5186 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bezlotoxumab is antibody binding of Enzyme (Toxin B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:f23d3330-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5188 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 radotinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.514']} DrugCentral uuid:f23d5bbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:5201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crisaborole targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f23d842a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13946 biolink:molecularly_interacts_with DrugCentral:5201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crisaborole targets Enzyme (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f23db922-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f23db922-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f23db922-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f23db922-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f23e0378-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baricitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f23e2c0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baricitinib is inhibitor of Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f23e55ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baricitinib is inhibitor of Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f23e7ef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baricitinib is inhibitor of Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.87']} DrugCentral uuid:f23ea792-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baricitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.276']} DrugCentral uuid:f23ed03c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baricitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.229']} DrugCentral uuid:f23ef940-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5202 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baricitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.244']} DrugCentral uuid:f23f21c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rucaparib is inhibitor of Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f23f4a44-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:5203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rucaparib is inhibitor of Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:f23f72da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:5203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:f23f9c10-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:5203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f23fc4a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:5203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:f23fed1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q460N5 biolink:molecularly_interacts_with DrugCentral:5203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:f2401596-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:5203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:f240403e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:f24069ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:f2409264-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:5203 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:f240bae6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:5208 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 plecanatide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.42']} DrugCentral uuid:f240e3c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19438 biolink:molecularly_interacts_with DrugCentral:5208 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 plecanatide targets Unclassified (Tumor necrosis factor receptor superfamily member 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:f2410c6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25092 biolink:molecularly_interacts_with DrugCentral:5208 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 plecanatide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.721']} DrugCentral uuid:f24134f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5209 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 icotinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:f2415e2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olmutinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f24187d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5210 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 olmutinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.036']} DrugCentral uuid:f241b05e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apatinib is inhibitor of Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f241d8ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.368']} DrugCentral uuid:f24202fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.276']} DrugCentral uuid:f2422b92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.886']} DrugCentral uuid:f242543c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5211 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f2427dc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17752 biolink:molecularly_interacts_with DrugCentral:5214 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 telotristat ethyl is inhibitor of Enzyme (Tryptophan 5-hydroxylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:f242a69e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclabuvir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:f242cf48-ac81-11ec-8b6b-0242ac110002 UniProtKB:O39930 biolink:molecularly_interacts_with DrugCentral:5215 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 beclabuvir targets Unclassified (RNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f242f7de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:5217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f2432074-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:5217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytisine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:f24349c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:5217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.47']} DrugCentral uuid:f243725e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:5217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:f2439af4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:5217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytisine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:f243c380-ac81-11ec-8b6b-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:5217 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cytisine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:f243ed60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:5218 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribociclib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:f244166e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5218 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribociclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.409']} DrugCentral uuid:f2443ffe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5218 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ribociclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f24468da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naldemedine is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:f24491a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5220 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 naldemedine is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:f244ba38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5221 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avelumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) DrugCentral uuid:f244dea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niraparib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:f24507b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:5222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niraparib targets Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f2453062-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:5222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f24558d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:5222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f2458170-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:5222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f245ae2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:5222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f245db02-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q460N5 biolink:molecularly_interacts_with DrugCentral:5222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:f2460398-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:5222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:f2462c38-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niraparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:f2465532-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5222 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 niraparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:f2467dd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:5223 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ocrelizumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.08']} DrugCentral uuid:f246a6fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24394 biolink:molecularly_interacts_with DrugCentral:5224 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dupilumab is antibody binding of Membrane receptor (Interleukin-4 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11.06']} DrugCentral uuid:f246cf9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:5226 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 deutetrabenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:f246f4d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:5227 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valbenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:f2471d82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:5227 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 valbenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.523']} DrugCentral uuid:f2474618-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8T9Z7 biolink:molecularly_interacts_with DrugCentral:5229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 forodesine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:f2476fbc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55859 biolink:molecularly_interacts_with DrugCentral:5229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 forodesine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.64']} DrugCentral uuid:f247994c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:5229 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 forodesine is inhibitor of Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.143']} DrugCentral uuid:f247c1ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f247ea78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f2481368-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f2483cee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:f2486598-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:f2488e9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f248b7be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f248e040-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f24908ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f2493176-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f2495c1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f24984f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f249ad68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f249d612-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f249feee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:f24a277a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:f24a501a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f24a78ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f24aa1f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f24aca86-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f24af308-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f24b1b94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f24b452e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f24b6dba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:f24b9650-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f24bbf4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f24be7d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f24c1044-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f24c39b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f24c62ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f24c8b5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:f24cb3d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22694 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f24cdcea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f24d0774-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f24d333e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f24d5ef4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:f24d8c08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:f24db52a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:f24dddac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f24e064c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f24e2f8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:f24e5818-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f24e809a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f24ea91c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f24ed324-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f24efdc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:f24f266c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f24f4eee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f24f77ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f24fa02e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f24fc8ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f24ff146-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f2501b80-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f2504402-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f2506ca2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:f250951a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:f250bfe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f250e86c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f2511102-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f25139e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f251627e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:f2518ae2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f251b396-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f251dcd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f252056c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f2522e02-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f252568e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f25280c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f252ab5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f252d3fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f252fc7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f2532564-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f2534de6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f25377b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49761 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f253a0d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f253ca00-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f253f28c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f2541c30-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f25444b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f25470c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f2549c3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f254c59a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f254ee80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:f2551720-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f2553fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f2556838-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f2559164-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:f255b9e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f255e272-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f2560afe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f2563614-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:f2565ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f2568722-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f256afae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f256d8a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49840 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Glycogen synthase kinase-3 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f2570134-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f25729d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:f25752d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:f2577b8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f257a42c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f257ccd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:f257f7ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f2582136-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f25849c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:f258724e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:f2589b34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f258c3c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f258ec60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f25914f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:f2593e5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:f25966f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f25990b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f259b956-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f259e4da-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f25a0e4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f25a36c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f25a6036-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f25a88b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f25ab14e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f25ad9d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f25b031a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f25b2b92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f25b541e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f25b7c8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f25ba6d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:f25bd0ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:f25bf98c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:f25c2222-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f25c4b12-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:f25c73a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f25c9c34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f25cc4ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:f25cede2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:f25d1650-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y243 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (RAC-gamma serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f25d3ef0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f25d6772-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f25d93aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f25dbf60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f25de878-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:f25e1172-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:f25e39fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f25e6280-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f25e8af8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:f25eb41a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f25edca6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDC3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase BRSK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f25f0528-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f25f2dbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f25f579e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f25f816a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:f25fa9ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:f25fd39a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f25ffc8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f2602534-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f2604dc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f260e03c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f2610ea4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f2613b18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f2616476-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f2618d34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IWQ3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase BRSK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f261b64c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f261dee2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f2620764-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f2623004-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:f2625930-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.13']} DrugCentral uuid:f26281da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:f262aa66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:f262d2fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f262fd5e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f263291e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f26351b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f2637a40-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:f263a326-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f263cbd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f263f448-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f2641cf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:f26447ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f2647094-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:f2649934-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f264c2c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f264eba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f2651436-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f2653cae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:f265658a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:f2658e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f265b6ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f265df6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f26609f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f266326c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43172 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Nuclear other (U4/U6 small nuclear ribonucleoprotein Prp4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:f2665b20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:f26683ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f266ae9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f266d776-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f2670002-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f2672884-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f2675174-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00750 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f2677a00-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75747 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f267a28c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:f267cafa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f267f444-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:f2681dc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f2684660-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f2687036-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:f26898d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f268c158-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f268ea0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f26912fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51817 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit PRKX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f2693b88-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:f269641e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5231 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 midostaurin is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f2698cdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:5232 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abaloparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f269b5f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brigatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:f269de94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brigatinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:f26a072a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brigatinib is inhibitor of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.137']} DrugCentral uuid:f26a2fca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brigatinib is inhibitor of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:f26a5af4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brigatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.721']} DrugCentral uuid:f26a83da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5233 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brigatinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.222']} DrugCentral uuid:f26aac5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5234 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 durvalumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) DrugCentral uuid:f26ad0f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5235 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cenegermin is agonist of Kinase (High affinity nerve growth factor receptor) DrugCentral uuid:f26af5cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08138 biolink:molecularly_interacts_with DrugCentral:5235 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cenegermin is agonist of Membrane receptor (Tumor necrosis factor receptor superfamily member 16) DrugCentral uuid:f26b1e3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5237 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sarilumab is antibody binding of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.1']} DrugCentral uuid:f26b1e3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5237 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sarilumab is antibody binding of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.1']} DrugCentral uuid:f26b522e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 evogliptin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:f26b7b6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5239 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 evogliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:f26ba3e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5240 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polmacoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f26bcd94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5240 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polmacoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f26bf72e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:5240 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polmacoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.081']} DrugCentral uuid:f26c2154-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5240 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polmacoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.081']} DrugCentral uuid:f26c4cce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betrixaban targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f26c7884-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:5241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betrixaban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:f26ca160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:5241 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 betrixaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:f26cca78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voxilaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.42']} DrugCentral uuid:f26cf336-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q81495 biolink:molecularly_interacts_with DrugCentral:5242 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voxilaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.18']} DrugCentral uuid:f26d1bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5244 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pibrentasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.19']} DrugCentral uuid:f26d444e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WMX2 biolink:molecularly_interacts_with DrugCentral:5244 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pibrentasvir targets Unclassified (Genome polyprotein [Cleaved into: Core protein p21) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f26d6d8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23945 biolink:molecularly_interacts_with DrugCentral:5245 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 corifollitropin alfa is agonist of GPCR (Follicle-stimulating hormone receptor) DrugCentral uuid:f26d964c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5246 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guselkumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:f26d964c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5246 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 guselkumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:f26dc4d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20273 biolink:molecularly_interacts_with DrugCentral:5247 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 inotuzumab ozogamicin is antibody binding of Membrane receptor (B-cell receptor CD22) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f26dee94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:f26e1734-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:5248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.801']} DrugCentral uuid:f26e3fc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5248 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f26e682e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:5250 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imrecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:f26e9114-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5250 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imrecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:f26eb9b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5250 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imrecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:f26ee254-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enasidenib targets Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f26f0aea-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enasidenib targets Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f26f3402-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48735 biolink:molecularly_interacts_with DrugCentral:5251 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enasidenib is inhibitor of Enzyme (Isocitrate dehydrogenase [NADP], mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f26f5c8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f26f8524-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:f26fadba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:f26fd8e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f2700170-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f27029fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f27052a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:f2707b96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f270a422-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f270cc9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f270f5bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f2711e34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f27146b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f2716f42-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f2719922-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f271c2f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:f271eb98-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:f272142e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f2723d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f2726596-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f2728e2c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f272b6cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f272e00c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f2730870-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f27330f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:f273597e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f27384c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f273ae10-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f273d76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f273fffa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f27428fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:f2745180-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:f2747a0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f274a338-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:f274cbd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f274f45a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f2751ce6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f27546bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:f275722c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f2759d92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f275c830-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:f275f0f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f276198e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f2764224-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:f2766ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f27693dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:f276bc72-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f276e4f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f2770d80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f27739c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f277644c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f2778cd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f277b6c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78368 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Casein kinase I isoform gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:f277e03e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6M4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Casein kinase I isoform gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:f27808d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f2783160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:f2785a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f2788318-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:f278ab9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:f278d444-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f278ff82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f2792b42-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:f27955d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f2797e6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:f279a748-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f279cfd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:f279f860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:f27a21aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f27a4a18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f27a72a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:f27a9b9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f27ac592-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f27af12a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:f27b1cae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f27b456c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f27b6e5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f27b96de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f27bbf6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f27be8dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f27c1208-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:f27c3ab2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f27c6348-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:f27c8bde-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f27cb514-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f27cdda0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f27d0622-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f27d2efe-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:f27d578a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f27d800c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f27da8ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:f27dd322-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f27dfbb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f27e2458-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:f27e4d02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:f27e77aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f27ea0b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f27ec94e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f27ef1da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:f27f1ad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:f27f436a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY57 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 32B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:f27f6c1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.62']} DrugCentral uuid:f27f94aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.036']} DrugCentral uuid:f27fbdd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5252 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 neratinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.229']} DrugCentral uuid:f27fe72a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:5256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 copanlisib is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:f2800fa2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.432']} DrugCentral uuid:f2803914-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.194']} DrugCentral uuid:f28061dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:f2808a7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5256 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:f280b362-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:5257 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 butylphthalide is blocker of Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:f280dc3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tivozanib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.65']} DrugCentral uuid:f28104a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:5258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tivozanib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:f2812d2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tivozanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.764']} DrugCentral uuid:f28155ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tivozanib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.788']} DrugCentral uuid:f2817eaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tivozanib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.375']} DrugCentral uuid:f281a7a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tivozanib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.866']} DrugCentral uuid:f281d044-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tivozanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.524']} DrugCentral uuid:f281f8d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.678']} DrugCentral uuid:f2822396-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.796']} DrugCentral uuid:f2824f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5258 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:f28279f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abemaciclib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:f282a28a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:5259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f282cbca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:f282f44c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f2831cb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f2834582-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:f2836e0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abemaciclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:f28396b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5259 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abemaciclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:f283c066-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acalabrutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:f283eb7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f2841700-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acalabrutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:f2843f96-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acalabrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:f2846804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acalabrutinib is inhibitor of Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:f2849144-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:5260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.032']} DrugCentral uuid:f284b9da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.434']} DrugCentral uuid:f284e27a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5260 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.292']} DrugCentral uuid:f2850afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:5261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 latanoprostene bunod targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:f2853414-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:5261 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 latanoprostene bunod is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:f285647a-ac81-11ec-8b6b-0242ac110002 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:f285647a-ac81-11ec-8b6b-0242ac110002 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:f285647a-ac81-11ec-8b6b-0242ac110002 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:f285a3cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01344 biolink:molecularly_interacts_with DrugCentral:5263 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 benralizumab is antibody binding of Membrane receptor (Interleukin-5 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.959']} DrugCentral uuid:f285cd84-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:5267 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 semaglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.42']} DrugCentral uuid:f285f6a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:5268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emicizumab is antibody binding of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.73']} DrugCentral uuid:f2861f50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00740 biolink:molecularly_interacts_with DrugCentral:5268 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emicizumab is antibody binding of Enzyme (Coagulation factor IX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f28647e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 netarsudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:f2867112-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5269 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 netarsudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.377']} DrugCentral uuid:f2869994-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:5270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertugliflozin targets Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.94']} DrugCentral uuid:f286c216-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NY91 biolink:molecularly_interacts_with DrugCentral:5270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertugliflozin targets Transporter (Low affinity sodium-glucose cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.06']} DrugCentral uuid:f286eaac-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:5270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertugliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.708']} DrugCentral uuid:f28713b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:5270 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ertugliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.057']} DrugCentral uuid:f2873c5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92847 biolink:molecularly_interacts_with DrugCentral:5271 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 macimorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:f28765c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:5272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 angiotensin II is agonist of GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.2']} DrugCentral uuid:f2878f20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:5272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 angiotensin II targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:f287b7ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:5272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 angiotensin II targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:f287e06a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:5272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 angiotensin II targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:f28808f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:5272 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 angiotensin II is agonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f2883204-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bictegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:f2885a68-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bictegravir targets Unclassified (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:f2888326-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:5274 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bictegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.125']} DrugCentral uuid:f288aba8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5275 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lutetium (177Lu) oxodotreotide is agonist of GPCR (Somatostatin receptor type 2) DrugCentral uuid:f288d092-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5276 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tezacaftor is pharmacological chaperone of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f288f900-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12908 biolink:molecularly_interacts_with DrugCentral:5277 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elobixibat is inhibitor of Transporter (Ileal sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.276']} DrugCentral uuid:f28921a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apalutamide is antagonist of Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f2894a54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5278 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 apalutamide is inhibitor of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:f28974a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01730 biolink:molecularly_interacts_with DrugCentral:5279 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibalizumab is antibody binding of Membrane receptor (T-cell surface glycoprotein CD4) DrugCentral uuid:f2899a18-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fostamatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f289c290-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fostamatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:f289eb26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fostamatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f28a145c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:5280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fostamatinib is inhibitor of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.092']} DrugCentral uuid:f28a3cd4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5280 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fostamatinib is inhibitor of Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.387']} DrugCentral uuid:f28a6948-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5281 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tildrakizumab is antibody binding of Cytokine (Interleukin-23) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:f28a6948-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5281 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tildrakizumab is antibody binding of Cytokine (Interleukin-23) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:f28a9db4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZV9 biolink:molecularly_interacts_with DrugCentral:5282 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 burosumab is antibody binding of Secreted (Fibroblast growth factor 23) DrugCentral uuid:f28ac244-ac81-11ec-8b6b-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:5283 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosnetupitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.022']} DrugCentral uuid:f28aef44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erenumab is antibody binding of GPCR (Calcitonin-gene-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.699']} DrugCentral uuid:f28aef44-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5284 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erenumab is antibody binding of GPCR (Calcitonin-gene-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.699']} DrugCentral uuid:f28b2464-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:5285 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avatrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:f28b4ebc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q25634 biolink:molecularly_interacts_with DrugCentral:5286 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxidectin is inhibitor of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:f28b7342-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f28b9bd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f28bc46e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol is agonist of GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:f28bedb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:f28c164e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f28c3eda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:f28c6770-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f28c906a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5S1 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:f28cb900-ac81-11ec-8b6b-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:f28ce18c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol is inhibitor of Ion channel (Transient receptor potential cation channel subfamily V member 1) DrugCentral uuid:f28d05fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:5288 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cannabidiol is antagonist of GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f28d3268-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:5289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 encorafenib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f28d5e3c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:5289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 encorafenib is inhibitor of Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:f28d89ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5289 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 encorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.328']} DrugCentral uuid:f28db300-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5290 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 binimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:f28ddba0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5290 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 binimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:f28e0440-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33815 biolink:molecularly_interacts_with DrugCentral:5291 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tecovirimat is inhibitor of Viral envelope protein (Envelope protein F13) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.382']} DrugCentral uuid:f28e2ccc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5292 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ivosidenib is inhibitor of Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.149']} DrugCentral uuid:f28e55d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5293 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elagolix targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f28e7e52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8SPZ1 biolink:molecularly_interacts_with DrugCentral:5293 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elagolix targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:f28ea724-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:5293 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elagolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:f28ecfa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:5295 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doravirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:f28ef986-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:5295 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doravirine targets Unclassified (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:f28f2334-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:5295 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 doravirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:f28f4ce2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5296 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f28f756e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5296 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:f28f9f6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5296 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.638']} DrugCentral uuid:f28fc816-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5296 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:f28ff0ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5297 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dacomitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:f29019a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5297 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dacomitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f2904214-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5297 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dacomitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f2906aa0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5297 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dacomitinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:f2909340-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5297 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dacomitinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:f290bd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5297 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dacomitinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.133']} DrugCentral uuid:f290e5ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5300 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talazoparib tosylate is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:f2910e56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5300 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 talazoparib tosylate is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:f29136f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:5301 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 baloxavir marboxil is inhibitor of Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.854']} DrugCentral uuid:f2916022-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:f29188ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.959']} DrugCentral uuid:f291b158-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:f291d9ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f29202de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:f2922b6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:f29253f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f2927c8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:f292a824-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.854']} DrugCentral uuid:f292d3b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:f2930076-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.569']} DrugCentral uuid:f29329fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5302 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lorlatinib is inhibitor of Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:f2935292-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:5303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:f2937b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:5303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f293a3f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:5303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:f293ccf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:5303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:f293f648-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:5303 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:f2941ef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P56726 biolink:molecularly_interacts_with DrugCentral:5304 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glasdegib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f2944788-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5304 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 glasdegib is antagonist of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:f294710e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 larotrectinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.187']} DrugCentral uuid:f294999a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 larotrectinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.092']} DrugCentral uuid:f294c244-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5305 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 larotrectinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.975']} DrugCentral uuid:f294eb34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5306 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gilteritinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:f2951492-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5306 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gilteritinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:f2954200-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5306 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gilteritinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f2956bcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5306 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gilteritinib is inhibitor of Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:f295949e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5306 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gilteritinib is inhibitor of Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f295bd2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5306 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gilteritinib is inhibitor of Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f295e624-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5306 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gilteritinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:f2960eb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5306 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gilteritinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:f2963804-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:5307 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 evocalcet is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.032']} DrugCentral uuid:f296609a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04275 biolink:molecularly_interacts_with DrugCentral:5308 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 caplacizumab is antibody binding of Unclassified (von Willebrand factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.509']} DrugCentral uuid:f2968a8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:5309 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lanadelumab is antibody binding of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:f296b306-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:5311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:f296dd18-ac81-11ec-8b6b-0242ac110002 UniProtKB:O02662 biolink:molecularly_interacts_with DrugCentral:5311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f2970590-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q28524 biolink:molecularly_interacts_with DrugCentral:5311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:f2972e26-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:5311 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vibegron is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:f297572a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5312 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 omidenepag isopropyl is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.081']} DrugCentral uuid:f297801a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:5313 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 patisiran is antisense inhibitor of RNA (transthyretin (TTR) mRNA) DrugCentral uuid:f297a4aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20273 biolink:molecularly_interacts_with DrugCentral:5314 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 moxetumomab pasudotox is binding agent of Membrane receptor (B-cell receptor CD22) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:f297cd36-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5315 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fremanezumab is antibody binding of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:f297f5d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5316 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 galcanezumab is antibody binding of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f298213c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:5317 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cemiplimab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.102']} DrugCentral uuid:f2984cf2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:5319 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 inotersen is antisense inhibitor of RNA (transthyretin (TTR) mRNA) DrugCentral uuid:f2987178-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:5320 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 emapalumab is antibody binding of Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.1']} DrugCentral uuid:f2989a0e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:5322 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ravulizumab is antibody binding of Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.357']} DrugCentral uuid:f298c740-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tagraxofusp is binding agent of Membrane receptor (Interleukin-3 receptor) DrugCentral uuid:f298c740-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5323 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tagraxofusp is binding agent of Membrane receptor (Interleukin-3 receptor) DrugCentral uuid:f298f5a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:5324 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexanolone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:f29925fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:f29925fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:f29925fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:f2996d58-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:f2996d58-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:f2996d58-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:f299b52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:f299b52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:f299b52e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:f299f516-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5325 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.088']} DrugCentral uuid:f29a1eb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:5325 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.432']} DrugCentral uuid:f29a475a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:5325 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.848']} DrugCentral uuid:f29a7018-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.125']} DrugCentral uuid:f29a9a52-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3']} DrugCentral uuid:f29ac2de-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95136 biolink:molecularly_interacts_with DrugCentral:5326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:f29aeb74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.409']} DrugCentral uuid:f29b1478-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5326 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.009']} DrugCentral uuid:f29b3d04-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:5327 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erdafitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:f29b6586-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:5327 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erdafitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:f29b8e1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5327 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erdafitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.434']} DrugCentral uuid:f29bb81a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5327 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:f29be3d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5327 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.921']} DrugCentral uuid:f29c0ed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5327 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.602']} DrugCentral uuid:f29c384e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5327 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.244']} DrugCentral uuid:f29c6170-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f29c8a06-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f29cb292-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f29cdb28-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Z1L0 biolink:molecularly_interacts_with DrugCentral:5328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f29d044a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5328 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 alpelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.337']} DrugCentral uuid:f29d2cf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:f29d5594-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:f29d7e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bremelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.02']} DrugCentral uuid:f29da940-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:5329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bremelanotide is agonist of GPCR (Adrenocorticotropic hormone receptor) DrugCentral uuid:f29dcdc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:5329 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:f29df76a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14980 biolink:molecularly_interacts_with DrugCentral:5330 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selinexor is inhibitor of Nuclear other (Exportin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:f29e20aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P60880 biolink:molecularly_interacts_with DrugCentral:5331 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 prabotulinumtoxinA is blocker of Cytosolic other (Synaptosomal-associated protein 25) DrugCentral uuid:f29e6434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f29e6434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f29e6434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f29e6434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f29e6434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f29e6434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f29e6434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f29e6434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f29e6434-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f29ed81a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40259 biolink:molecularly_interacts_with DrugCentral:5333 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 polatuzumab vedotin is antibody binding of Tumour-associated antigen (B-cell antigen receptor complex-associated protein beta chain) DrugCentral uuid:f29efcaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5334 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darolutamide is antagonist of Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f29f2554-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:5334 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darolutamide is antagonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:f29f49da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5334 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 darolutamide is inhibitor of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.187']} DrugCentral uuid:f29f7540-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02656 biolink:molecularly_interacts_with DrugCentral:5335 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 volanesorsen is antisense inhibitor of RNA (apolipoprotein C-III (apoC-III) mRNA) DrugCentral uuid:f29f9b4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5337 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 risankizumab is inhibitor of Cytokine (Interleukin-23 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:f29fc810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropeginterferon alfa-2b is binding agent of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f29fc810-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5338 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ropeginterferon alfa-2b is binding agent of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:f29ff754-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:5339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sotagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:f2a01ff4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:5339 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sotagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.444']} DrugCentral uuid:f2a0490c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f2a07198-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:f2a09ab0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f2a0c33c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f2a0ebc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f2a1145e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:f2a13eca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:f2a16ba2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:f2a1967c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f2a1bf08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f2a1e834-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:f2a210c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f2a23938-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f2a261ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f2a28ad2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:f2a2b372-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f2a2dc08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:f2a30584-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f2a32e2e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:f2a356c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f2a37f64-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:f2a3a8a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:f2a3d13a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:f2a3f9d0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:f2a42270-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f2a44b74-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:f2a4740a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:f2a49ca0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:f2a4c536-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f2a4f04c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f2a5195a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f2a541dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f2a56c48-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f2a595a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:f2a5be32-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:f2a5e6dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f2a60fe0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:f2a63894-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5341 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 quizartinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.796']} DrugCentral uuid:f2a6612a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8RL90 biolink:molecularly_interacts_with DrugCentral:5342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 relebactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f2a689b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2PUH3 biolink:molecularly_interacts_with DrugCentral:5342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:f2a6b328-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9X5A7 biolink:molecularly_interacts_with DrugCentral:5342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f2a6dc4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q93LQ9 biolink:molecularly_interacts_with DrugCentral:5342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f2a704ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q93DC4 biolink:molecularly_interacts_with DrugCentral:5342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:f2a72d80-ac81-11ec-8b6b-0242ac110002 UniProtKB:B1PL86 biolink:molecularly_interacts_with DrugCentral:5342 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f2a756c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pexidartinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f2a77f4c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pexidartinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:f2a7a7d8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pexidartinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:f2a7d05a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pexidartinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:f2a7f936-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:5343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pexidartinib is inhibitor of Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f2a821cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pexidartinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.56']} DrugCentral uuid:f2a84a58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pexidartinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:f2a872ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5343 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pexidartinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.88']} DrugCentral uuid:f2a89e86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f2a8c910-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:f2a8f188-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f2a91a0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:f2a9430e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f2a96ca8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f2a9952a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:f2a9be42-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.67']} DrugCentral uuid:f2a9e6ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:f2aa0fbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f2aa3854-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f2aa622a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib is inhibitor of Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f2aa8ac0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f2aab360-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:f2aadc00-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f2ab0522-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:f2ab2dcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5345 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 entrectinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:f2ab5662-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 upadacitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f2ab8024-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:f2aba932-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:f2abd254-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5346 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f2abfaea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:f2ac238a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f2ac4fb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:f2ac78a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f2aca13e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:f2acca6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f2acf300-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f2ad1b78-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:f2ad43fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f2ad6e2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:f2ad96b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:f2adbf24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f2ade7ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f2ae1258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f2ae3d14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f2ae65a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f2ae8e4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:f2aeb794-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f2aee034-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f2af08c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f2af3160-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f2af5a50-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:f2af82e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f2afab7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:f2afd4da-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f2affd66-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f2b025fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:f2b04e92-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f2b077c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f2b0a054-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f2b0c8f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f2b0f162-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:f2b11a5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:f2b142f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f2b16d7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f2b19612-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f2b1c132-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f2b1e9be-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:f2b2124a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f2b23ae0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:f2b26420-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:f2b28d24-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:f2b2b5c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f2b2de50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f2b30740-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f2b32fd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f2b35862-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f2b381fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:f2b3ad8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f2b3d918-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f2b404a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f2b42f3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:f2b457b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:f2b48052-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f2b4a8fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:f2b4d1ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f2b4fa8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f2b5230e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:f2b54ba4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:f2b57606-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f2b59e9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:f2b5c728-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f2b5f090-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f2b6191c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f2b641bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:f2b66a34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f2b6932e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f2b6bba6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f2b6e446-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:f2b70cc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f2b7366c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f2b75ef8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:f2b788b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:f2b7b146-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.5']} DrugCentral uuid:f2b7da86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:f2b8031c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f2b82bb2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f2b85448-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f2b87d38-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:f2b8a5ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f2b8ce46-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f2b8f6d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:f2b921f2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f2b94a60-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:f2b973dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:f2b99d9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f2b9c620-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f2b9eec0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f2ba174c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:f2ba403c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:f2ba68c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:f2ba915e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f2bab9ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f2bae42e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:f2bb0cba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f2bb3532-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f2bb5dc8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f2bb8712-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:f2bbafa8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f2bbd834-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f2bc00ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:f2bc29ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f2bc5264-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f2bc7afa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:f2bca41c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f2bccef6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f2bcf76e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:f2bd1ff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:f2bd48fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f2bd7388-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f2bd9c14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f2bdc4a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f2bdedcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f2be1676-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f2be3f0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f2be67a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f2be915a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f2beb9fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:f2bee286-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f2bf0b12-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:f2bf3402-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:f2bf5c98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:f2bf851a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f2bfadba-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:f2bfd704-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:f2bfff90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f2c02826-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:f2c05242-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f2c07b1e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f2c0a3c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f2c0cc54-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f2c0f54e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f2c11dd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:f2c14652-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f2c16fce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f2c19918-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:f2c1c1c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f2c1ea58-ac81-11ec-8b6b-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f2c212f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f2c23d82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:f2c26618-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f2c28eae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f2c2b726-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:f2c2e02a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:f2c308c0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:f2c3314c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f2c359ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f2c38430-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f2c3acd0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f2c3d566-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f2c3ff5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f2c4282c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:f2c450b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:f2c47944-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:f2c4a220-ac81-11ec-8b6b-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f2c4caac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f2c4f32e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f2c51bb0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f2c544dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:f2c56e62-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:f2c596ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f2c5bf84-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:f2c5eaf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f2c61394-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f2c63c20-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f2c66498-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:f2c68d92-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f2c6b61e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:f2c6deaa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:f2c7088a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f2c73120-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f2c759b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f2c78238-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:f2c7abe6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:f2c7d486-ac81-11ec-8b6b-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:f2c7fd1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f2c82594-ac81-11ec-8b6b-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:f2c84eac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:f2c87738-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f2c89fce-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f2c8c85a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f2c8f19a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f2c91a26-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:f2c943fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:f2c96e7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6P3R8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f2c997e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TD19 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:f2c9c070-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f2c9e910-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:f2ca11e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:f2ca3a82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f2ca630e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:f2ca8b9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:f2cab4da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:f2cadd66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:f2cb0606-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H4B4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f2cb2e7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f2cb589a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:f2cb8464-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:f2cbad4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:f2cbd5e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f2cbfeda-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f2cc275c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:f2cc4fde-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:f2cc7860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:f2cca1aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:f2ccca4a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:f2ccf2e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:f2cd1b8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f2cd4614-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f2cd6fb8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.05']} DrugCentral uuid:f2cd984e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:f2cdc1e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f2cdeac4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:f2ce1364-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f2ce3bf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f2ce6530-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f2ce8db2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f2ceb63e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:f2cedeca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f2cf08aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f2cf3140-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f2cf59ea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f2cf83ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:f2cfacce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:f2cfd56e-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:f2cffdfa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:f2d026a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f2d04fee-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15208 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f2d07884-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:f2d0a124-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:f2d0ca82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:f2d0f340-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f2d11bc2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f2d1443a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:f2d16e1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f2d196b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:f2d1bf46-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f2d1e7e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:f2d21126-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:f2d239b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f2d26234-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:f2d28ad4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f2d2b496-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f2d2dd40-ac81-11ec-8b6b-0242ac110002 UniProtKB:O76039 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase-like 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:f2d305cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f2d32e6c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f2d35752-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f2d37fe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:f2d3a874-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:f2d3d11e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:f2d3fa54-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:f2d422f4-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:f2d44b80-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f2d475b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:f2d4a13e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f2d4caba-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BQI3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:f2d4f33c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f2d51c18-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NRH2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (SNF-related serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:f2d54490-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f2d56f06-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f2d597a6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f2d5c0f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f2d5e97c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:f2d61212-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:f2d63a9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:f2d66622-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.79']} DrugCentral uuid:f2d68f1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:f2d6b7a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9HC98 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:f2d6e03e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:f2d7092e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51957 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:f2d731c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q58F21 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Unclassified (Bromodomain testis-specific protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f2d75a50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96PY6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f2d78386-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:f2d7ac12-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:f2d7d4a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:f2d7fd3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:f2d82732-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5347 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f2d852ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P26433 biolink:molecularly_interacts_with DrugCentral:5349 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenapanor targets Transporter (Sodium/hydrogen exchanger 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:f2d87b60-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48764 biolink:molecularly_interacts_with DrugCentral:5349 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tenapanor is inhibitor of Transporter (Sodium/hydrogen exchanger 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.06']} DrugCentral uuid:f2d8a3f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:5350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f2d8ccf0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:5350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:f2d8f572-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:5350 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:f2d91dfe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:5351 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lasmiditan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:f2d94784-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f2d97100-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q07806 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f2d99996-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f2d9c308-ac81-11ec-8b6b-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f2d9eb9e-ac81-11ec-8b6b-0242ac110002 UniProtKB:G1C775 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:f2da181c-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6T4V3 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:f2da440e-ac81-11ec-8b6b-0242ac110002 UniProtKB:H4I819 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase MrdA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f2da6d30-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0A0W8ASI8 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase MrdA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:f2da9616-ac81-11ec-8b6b-0242ac110002 UniProtKB:A6T4M7 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:f2dabeca-ac81-11ec-8b6b-0242ac110002 UniProtKB:G3XD46 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:f2dae788-ac81-11ec-8b6b-0242ac110002 UniProtKB:D0CCM7 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:f2db1032-ac81-11ec-8b6b-0242ac110002 UniProtKB:A0A5E6DR09 biolink:molecularly_interacts_with DrugCentral:5352 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:f2db3972-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5353 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 zanubrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:f2db6212-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13196 biolink:molecularly_interacts_with DrugCentral:5354 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 givosiran is antisense inhibitor of RNA (aminolevulinate synthase1 (ALAS1) mRNA) DrugCentral uuid:f2db87ba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:5355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:f2dbb05a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:5355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:f2dbdb34-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:5355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:f2dc0460-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:5355 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:f2dc2cf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:5356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:f2dc558c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:5356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:f2dc7e9a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:f2dca776-ac81-11ec-8b6b-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:5356 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 voxelotor is inhibitor of Transporter (hemoglobin subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:f2dccfee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5357 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 golodirsen is antisense inhibitor of RNA (exon 53 of dystrophin pre-mRNA) DrugCentral uuid:f2dcf456-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumateperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:f2dd211a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumateperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:f2dd4adc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:5358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumateperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:f2dd7390-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumateperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:f2dd9d2a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:5358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumateperone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:f2ddc8ae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumateperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:f2ddf194-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumateperone is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:f2de1a3e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumateperone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:f2de43b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumateperone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:f2de6c50-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5358 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumateperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:f2de94f0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99572 biolink:molecularly_interacts_with DrugCentral:5359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brilliant Blue G is antagonist of Ion channel (P2X purinoceptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f2debd86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P37840 biolink:molecularly_interacts_with DrugCentral:5359 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brilliant Blue G targets Transporter (Alpha-synuclein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:f2dee69e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5360 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lemborexant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f2df0f34-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:5360 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lemborexant is antagonist of GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:f2df37de-ac81-11ec-8b6b-0242ac110002 UniProtKB:O43614 biolink:molecularly_interacts_with DrugCentral:5360 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lemborexant is antagonist of GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f2df6088-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5361 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ubrogepant is antagonist of GPCR (Calcitonin gene-related peptide type 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.2']} DrugCentral uuid:f2df8be4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9BQB4 biolink:molecularly_interacts_with DrugCentral:5362 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 romosozumab is binding agent of Glycoprotein (Sclerostin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.7']} DrugCentral uuid:f2dfb772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5363 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 brolucizumab is inhibitor of Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f2dfe0b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95390 biolink:molecularly_interacts_with DrugCentral:5364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 luspatercept is binding agent of Cytokine (Growth/differentiation factor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.13']} DrugCentral uuid:f2e00952-ac81-11ec-8b6b-0242ac110002 UniProtKB:O14793 biolink:molecularly_interacts_with DrugCentral:5364 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 luspatercept is binding agent of Cytokine (Growth/differentiation factor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.69']} DrugCentral uuid:f2e03260-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16109 biolink:molecularly_interacts_with DrugCentral:5365 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 crizanlizumab is inhibitor of Adhesion (P-selectin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:f2e079d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f2e079d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f2e079d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f2e079d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f2e079d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f2e079d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f2e079d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f2e079d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f2e079d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:f2e0f042-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96NY8 biolink:molecularly_interacts_with DrugCentral:5366 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Nectin-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.24']} DrugCentral uuid:f2e118ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5367 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab deruxtecan is binding agent of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:f2e141aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:5367 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trastuzumab deruxtecan is inhibitor of Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:f2e16b1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P60880 biolink:molecularly_interacts_with DrugCentral:5368 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 botulinum toxin type A is blocker of Cytosolic other (Synaptosomal-associated protein 25) DrugCentral uuid:f2e18fac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:5371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roxadustat targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:f2e1b838-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:f2e1e1be-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f2e20d56-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5371 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:f2e235ec-ac81-11ec-8b6b-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5372 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 elexacaftor targets Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:f2e25e6e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:5375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cepharanthine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f2e2875e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cepharanthine is inhibitor of Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) DrugCentral uuid:f2e2abc6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:5375 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cepharanthine is inhibitor of Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) DrugCentral uuid:f2e2d0f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DTD1 biolink:molecularly_interacts_with DrugCentral:5376 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remdesivir is inhibitor of Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f2e2f978-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5378 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefuparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:f2e32362-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5378 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 mefuparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:f2e34dba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P05532 biolink:molecularly_interacts_with DrugCentral:5379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avapritinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:f2e37664-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avapritinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.57']} DrugCentral uuid:f2e39efa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5379 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 avapritinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:f2e3c812-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75530 biolink:molecularly_interacts_with DrugCentral:5380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazemetostat targets Unclassified (Polycomb protein EED) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f2e3f09e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92800 biolink:molecularly_interacts_with DrugCentral:5380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazemetostat is inhibitor of Enzyme (Histone-lysine N-methyltransferase EZH1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:f2e4193e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15910 biolink:molecularly_interacts_with DrugCentral:5380 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tazemetostat is inhibitor of Enzyme (Histone-lysine N-methyltransferase EZH2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f2e441de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5381 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 rimegepant is antagonist of GPCR (Calcitonin gene-related peptide type 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.56']} DrugCentral uuid:f2e46af6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P53396 biolink:molecularly_interacts_with DrugCentral:5382 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bempedoic acid is inhibitor of Enzyme (ATP-citrate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:f2e4947c-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f2e4bd08-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:f2e4e594-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95136 biolink:molecularly_interacts_with DrugCentral:5383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:f2e50fc4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ozanimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:f2e53850-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5383 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ozanimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f2e560c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:5384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osilodrostat targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:f2e589cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15539 biolink:molecularly_interacts_with DrugCentral:5384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:f2e5b262-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15393 biolink:molecularly_interacts_with DrugCentral:5384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:f2e5dada-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30099 biolink:molecularly_interacts_with DrugCentral:5384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:f2e6037a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:5384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osilodrostat is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:f2e62c88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:5384 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 osilodrostat is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:f2e65532-ac81-11ec-8b6b-0242ac110002 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:5385 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 isatuximab is binding agent of Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f2e67efe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eptinezumab is binding agent of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.82']} DrugCentral uuid:f2e6a7c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10092 biolink:molecularly_interacts_with DrugCentral:5386 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 eptinezumab is binding agent of GPCR (Calcitonin gene-related peptide 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.24']} DrugCentral uuid:f2e6d200-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5387 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 teprotumumab is antagonist of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f2e6fa8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selumetinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:f2e723b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selumetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f2e74c44-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5388 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selumetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:f2e77570-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tucatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:f2e79e06-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tucatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:f2e7ca8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tucatinib is inhibitor of Kinase (ERBB2/ERBB3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:f2e7ca8e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5389 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tucatinib is inhibitor of Kinase (ERBB2/ERBB3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:f2e7fed2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:f2e82768-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f2e850e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:f2e87998-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5390 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:f2e8a3b4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55899 biolink:molecularly_interacts_with DrugCentral:5391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sacituzumab govitecan is antibody binding of Membrane receptor (IgG receptor FcRn large subunit p51) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.71']} DrugCentral uuid:f2e8cc68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:5391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sacituzumab govitecan is binding agent of Enzyme (DNA topoisomerase 1) DrugCentral uuid:f2e8f0e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09758 biolink:molecularly_interacts_with DrugCentral:5391 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sacituzumab govitecan is antibody binding of Tumour-associated antigen (Tumor-associated calcium signal transducer 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.58']} DrugCentral uuid:f2e91984-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5392 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 capmatinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.88']} DrugCentral uuid:f2e942ce-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selpercatinib is inhibitor of Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:f2e96b5a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5393 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 selpercatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:f2e993fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripretinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:f2e9bc7c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripretinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:f2e9e56c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripretinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:f2ea0df8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripretinib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:f2ea3684-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripretinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f2ea5f1a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5394 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ripretinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:f2ea899a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:5395 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fluoroestradiol F 18 is binding agent of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.07']} DrugCentral uuid:f2eab24e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:5396 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 flortaucipir F 18 is binding agent of Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:f2eadb02-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 inebilizumab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:f2eb0384-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5397 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 inebilizumab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.8']} DrugCentral uuid:f2eb34bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f2eb34bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f2eb34bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:f2eb7c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f2eb7c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f2eb7c24-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:f2ebc49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f2ebc49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f2ebc49a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:f2ec0cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:f2ec0cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:f2ec0cb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:f2ec63c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:f2ec63c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:f2ec63c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:f2ec63c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:f2ec63c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:f2ec63c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:f2ec63c8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:f2eccff2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:5401 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fostemsavir is inhibitor of Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.08']} DrugCentral uuid:f2ecf96e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32320 biolink:molecularly_interacts_with DrugCentral:5402 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 inqovi is inhibitor of Enzyme (Cytidine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:f2ed21fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:5403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f2ed4a86-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:5403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f2ed7312-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:5403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:f2ed9c16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:5403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f2edc4b6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51685 biolink:molecularly_interacts_with DrugCentral:5403 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f2eded6a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5404 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tafasitamab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.39']} DrugCentral uuid:f2ee16dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P55899 biolink:molecularly_interacts_with DrugCentral:5405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (IgG receptor FcRn large subunit p51) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:f2ee3fa4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12314 biolink:molecularly_interacts_with DrugCentral:5405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (High affinity immunoglobulin gamma Fc receptor I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:f2ee6876-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:f2ee9260-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02223 biolink:molecularly_interacts_with DrugCentral:5405 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 belantamab mafodotin is binding agent of Tumour-associated antigen (Tumor necrosis factor receptor superfamily member 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:f2eebb82-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:5406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oliceridine targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f2eee418-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oliceridine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f2ef0cae-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oliceridine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:f2ef3562-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oliceridine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:f2ef5e7a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oliceridine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:f2ef8706-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:5406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oliceridine targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f2efaf88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:5406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oliceridine is agonist of GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:f2efd832-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5406 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 oliceridine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:f2f0035c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5408 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 viltolarsen is binding agent of RNA (exon 53 of dystrophin pre-mRNA) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:f2f033e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5409 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 satralizumab is antagonist of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f2f033e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5409 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 satralizumab is antagonist of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f2f067fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5410 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 clascoterone is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f2f09128-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5411 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 copper dotatate Cu-64 is binding agent of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.69']} DrugCentral uuid:f2f0baea-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralsetinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:f2f0e380-ac81-11ec-8b6b-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralsetinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f2f10c0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralsetinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f2f13506-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralsetinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:f2f15d7e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralsetinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:f2f185f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralsetinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:f2f1ae8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralsetinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:f2f1d9de-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralsetinib is inhibitor of Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:f2f20418-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralsetinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:f2f22cd6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5412 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pralsetinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:f2f25652-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5413 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 somapacitan targets GPCR (Growth hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.04']} DrugCentral uuid:f2f27fce-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:5414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lonafarnib is inhibitor of Cytosolic other (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:f2f2a864-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:f2f2d0dc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01111 biolink:molecularly_interacts_with DrugCentral:5414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase NRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:f2f2f9e0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:5414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:f2f32258-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:f2f34ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:5414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lonafarnib is inhibitor of Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:f2f34ee0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:5414 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lonafarnib is inhibitor of Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:f2f382fc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UJM8 biolink:molecularly_interacts_with DrugCentral:5415 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 lumasiran is antisense inhibitor of RNA (Hydroxyacid oxidase 1 (HAO1) mRNA) DrugCentral uuid:f2f3a8d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:f2f3d180-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:f2f3fa34-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 setmelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:f2f422ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:f2f44c28-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:f2f474e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 setmelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:f2f49da4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:5416 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.68']} DrugCentral uuid:f2f4c662-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:5417 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bulevirtide is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:f2f4fb0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:f2f4fb0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:f2f4fb0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:f2f4fb0a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:f2f53de0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:f2f56680-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f2f59286-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:f2f5baf4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f2f5e36c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:f2f60d88-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:f2f6372c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:f2f65fcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:f2f68880-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:f2f6b1ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:f2f6da56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:f2f7030a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5419 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:f2f72bd2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vadadustat targets Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f2f75602-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:5420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vadadustat targets Enzyme (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:f2f77eb6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vadadustat targets Unclassified (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:f2f7a738-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8N543 biolink:molecularly_interacts_with DrugCentral:5420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vadadustat targets Unclassified (Prolyl 3-hydroxylase OGFOD1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f2f7cfe2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:5420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vadadustat targets Unclassified (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:f2f7f918-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:f2f821cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.93']} DrugCentral uuid:f2f84ac6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5420 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:f2f87384-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5421 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.46']} DrugCentral uuid:f2f89c74-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5421 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:f2f8c532-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5421 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:f2f8eddc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:5422 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 borofalan (10B) is substrate of Transporter (L-type amino acid transporter 1) DrugCentral uuid:f2f913d4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirabrutinib hydrochloride targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f2f93dbe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirabrutinib hydrochloride targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f2f96668-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirabrutinib hydrochloride targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f2f98f8a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirabrutinib hydrochloride targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:f2f9b8a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:f2f9e110-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:f2fa0a8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:5423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:f2fa330e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:f2fa5c1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f2fa84bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5423 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:f2faad48-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:5424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tepotinib is inhibitor of Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:f2fad5ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5424 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tepotinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:f2fafff0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:5425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dotinurad is inhibitor of Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f2fb2890-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:5425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:f2fb5130-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:5425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:f2fb79a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dotinurad is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:f2fba360-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:5425 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:f2fbcbd8-ac81-11ec-8b6b-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delgocitinib is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:f2fbf482-ac81-11ec-8b6b-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:f2fc1e94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:f2fc4752-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:f2fc7006-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5426 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 delgocitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:f2fc98b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f2fcc286-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:f2fceb3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5427 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:f2fd13ee-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:5428 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sofpironium bromide is inhibitor of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:f2fd395a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07288 biolink:molecularly_interacts_with DrugCentral:5429 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 gallium (68Ga) gozetotide is binding agent of Surface antigen (Prostate-specific antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:f2fd6290-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:5430 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 berotralstat is inhibitor of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:f2fd8b30-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirbanibulin is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:f2fdb3a8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirbanibulin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f2fddc5c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirbanibulin is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:f2fe061e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5431 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 tirbanibulin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:f2fe2ea0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:f2fe572c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:f2fe7fcc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:5432 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:f2feaa56-ac81-11ec-8b6b-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5433 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ansuvimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:f2fed328-ac81-11ec-8b6b-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 margetuximab is antagonist of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.55']} DrugCentral uuid:f2fefbdc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5434 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 margetuximab is antagonist of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:f2ff24cc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atoltivimab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:f2ff4e20-ac81-11ec-8b6b-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5436 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 atoltivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:f2ff76de-ac81-11ec-8b6b-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5437 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 maftivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:f2ff9fba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5438 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 odesivimab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:f2ffc8e6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5438 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 odesivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:f2fff186-ac81-11ec-8b6b-0242ac110002 UniProtKB:P20595 biolink:molecularly_interacts_with DrugCentral:5439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vericiguat is activator of Enzyme (Guanylate cyclase soluble subunit beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:f3001a1c-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:5439 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 vericiguat is activator of Enzyme (Guanylate cyclase soluble subunit beta-1) DrugCentral uuid:f3003e98-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabotegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f3006800-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabotegravir targets Unclassified (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f30090aa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:5440 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 cabotegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:f300b940-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:f300e1d6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:f3010b16-ac81-11ec-8b6b-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:f3013456-ac81-11ec-8b6b-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.21']} DrugCentral uuid:f3015cf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:5441 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 umbralisib is inhibitor of Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f3018596-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilaciclib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:f301ae90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:5442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:f301d820-ac81-11ec-8b6b-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:5442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f30201f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:5442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:f3022a8c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:f302553e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:f3027dde-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilaciclib is inhibitor of Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:f302a688-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6ZWH5 biolink:molecularly_interacts_with DrugCentral:5442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilaciclib is inhibitor of Kinase (Serine/threonine-protein kinase Nek10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.57']} DrugCentral uuid:f302cf32-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:f302f8a4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5442 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:f303214e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5443 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 casimersen is antisense inhibitor of RNA (exon 53 of dystrophin pre-mRNA) DrugCentral uuid:f30345ac-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9NZB8 biolink:molecularly_interacts_with DrugCentral:5444 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 fosdenopterin targets Enzyme (Molybdenum cofactor biosynthesis protein 1) DrugCentral uuid:f3036a14-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:f3039322-ac81-11ec-8b6b-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f303bb90-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:f303e426-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5446 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:f3040c94-ac81-11ec-8b6b-0242ac110002 UniProtKB:P47871 biolink:molecularly_interacts_with DrugCentral:5447 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dasiglucagon is agonist of GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:f30438c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9Y5C1 biolink:molecularly_interacts_with DrugCentral:5449 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 evinacumab is inhibitor of Secreted (Angiopoietin-related protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:f3046176-ac81-11ec-8b6b-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:5450 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estetrol is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:f3048a16-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:5450 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 estetrol is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:f304b36a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:5451 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 dostarlimab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:f304dc14-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5452 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 loncastuximab tesirine is antibody binding of Surface antigen (B-lymphocyte antigen CD19) DrugCentral uuid:f3050090-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5453 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 bamlanivimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.15']} DrugCentral uuid:f305294e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5454 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 etesevimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:f3055248-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5455 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 casirivimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.34']} DrugCentral uuid:f3057afc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5456 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 imdevimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.33']} DrugCentral uuid:f305a3c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01024 biolink:molecularly_interacts_with DrugCentral:5457 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 pegcetacoplan is inhibitor of Unclassified (Complement C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:f305cdea-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04609 biolink:molecularly_interacts_with DrugCentral:5458 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 piflufolastat F-18 is binding agent of Enzyme (Glutamate carboxypeptidase 2) DrugCentral uuid:f305f46e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f3062010-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f3064afe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f306739e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:f3069cc0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f306c560-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f306edf6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f30716a0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f3073fae-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f307683a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f30790e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f307baa6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f307e4b8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f3080d3a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f30835c6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f3085ef2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f3088788-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:f308b032-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:f308d8d2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f30901c2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f3092a4e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f30952da-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f3097b66-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f309a582-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:f309cefe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f309f780-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f30a1ff8-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:f30a4974-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f30a71f6-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:f30a9a96-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:f30ac322-ac81-11ec-8b6b-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f30aec08-ac81-11ec-8b6b-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:f30b1494-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f30b3d0c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:f30b6750-ac81-11ec-8b6b-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:f30b92e8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:f30bbb9c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:f30be432-ac81-11ec-8b6b-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f30c0d68-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f30c35fe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f30c5e80-ac81-11ec-8b6b-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:f30c86f8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:f30cafe8-ac81-11ec-8b6b-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:f30cd860-ac81-11ec-8b6b-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:f30d00e2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:f30d295a-ac81-11ec-8b6b-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:f30d53bc-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:f30d7c48-ac81-11ec-8b6b-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:f30da5b0-ac81-11ec-8b6b-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:f30dcf72-ac81-11ec-8b6b-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:f30df89e-ac81-11ec-8b6b-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:f30e212a-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:f30e49ca-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:f30e72c4-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:f30e9b50-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:f30ec3fa-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:f30eec90-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) DrugCentral uuid:f30f1256-ac81-11ec-8b6b-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) DrugCentral uuid:f30f39a2-ac81-11ec-8b6b-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) DrugCentral uuid:f30f60e4-ac81-11ec-8b6b-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5459 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) DrugCentral uuid:f30f8560-ac81-11ec-8b6b-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 samidorphan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.28']} DrugCentral uuid:f30faebe-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:5460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 samidorphan is partial agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:f30fd772-ac81-11ec-8b6b-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5460 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 samidorphan is partial agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:f310001c-ac81-11ec-8b6b-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5461 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 sotorasib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:f31028b2-ac81-11ec-8b6b-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:5462 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrexafungerp is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:f310522e-ac81-11ec-8b6b-0242ac110002 UniProtKB:Q6FTN8 biolink:molecularly_interacts_with DrugCentral:5462 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrexafungerp is inhibitor of Enzyme (1,3-Beta-D-glucan-UDP glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:f3107aba-ac81-11ec-8b6b-0242ac110002 UniProtKB:P87204 biolink:molecularly_interacts_with DrugCentral:5462 biolink:DrugToGeneAssociation|biolink:Association RO:0002436 ibrexafungerp is inhibitor of Enzyme (1,3-Beta-D-glucan-UDP glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.97']} DrugCentral