subject	predicate	object	relation	provided_by	comment	type
DrugCentral:4	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central		biolink:Association
DrugCentral:4	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:4	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of wild-type human ERG channel expressed in HEK293 cells assessed as blockade of potassium tail current by whole-cell patch clamp technique	biolink:Association
DrugCentral:4	biolink:molecularly_interacts_with	UniProtKB:Q9UK17	RO:0002436	drug_central		biolink:Association
DrugCentral:4	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:4	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:4	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central		biolink:Association
DrugCentral:4	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:5	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:6	biolink:molecularly_interacts_with	UniProtKB:O15554	RO:0002436	drug_central		biolink:Association
DrugCentral:6	biolink:molecularly_interacts_with	UniProtKB:O60840	RO:0002436	drug_central		biolink:Association
DrugCentral:6	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Recombinant Cav1.3 calcium channel complexes expressed in tsA-cells	biolink:Association
DrugCentral:6	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:13	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:21	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central	Inhibitory activity against Leu22-Phe mutant human Dihydrofolate reductase	biolink:Association
DrugCentral:24	biolink:molecularly_interacts_with	UniProtKB:Q9BY41	RO:0002436	drug_central	Inhibition of human recombinant HDAC8	biolink:Association
DrugCentral:24	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central	Inhibition of human recombinant HDAC1	biolink:Association
DrugCentral:24	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central	Inhibition of human recombinant HDAC2	biolink:Association
DrugCentral:24	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central	Inhibition of aldose reductase	biolink:Association
DrugCentral:25	biolink:molecularly_interacts_with	UniProtKB:P26358	RO:0002436	drug_central		biolink:Association
DrugCentral:25	biolink:molecularly_interacts_with	UniProtKB:Q9Y6K1	RO:0002436	drug_central	Mechanism of Action; CHEMBL1992; SINGLE PROTEIN	biolink:Association
DrugCentral:26	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central		biolink:Association
DrugCentral:26	biolink:molecularly_interacts_with	UniProtKB:Q96J66	RO:0002436	drug_central		biolink:Association
DrugCentral:26	biolink:molecularly_interacts_with	UniProtKB:O15440	RO:0002436	drug_central		biolink:Association
DrugCentral:30	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:30	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of MAO-A activity	biolink:Association
DrugCentral:30	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of acetylcholinesterase (unknown origin) using acetylcholine iodide as substrate preincubated for 15 mins prior to substrate addition by spectrophotometric analysis	biolink:Association
DrugCentral:35	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central		biolink:Association
DrugCentral:38	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094124; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:38	biolink:molecularly_interacts_with	UniProtKB:O60391	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094124; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:38	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094124; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:38	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094124; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:38	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094124; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:38	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094124; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:38	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094124; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:38	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:38	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:38	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:39	biolink:molecularly_interacts_with	UniProtKB:O43451	RO:0002436	drug_central		biolink:Association
DrugCentral:39	biolink:molecularly_interacts_with	UniProtKB:P14410	RO:0002436	drug_central	C-terminal catalytic subunit	biolink:Association
DrugCentral:39	biolink:molecularly_interacts_with	UniProtKB:P10253	RO:0002436	drug_central	Inhibition of maltase in human Caco-2 cell model system after 2 hrs	biolink:Association
DrugCentral:39	biolink:molecularly_interacts_with	UniProtKB:P04745	RO:0002436	drug_central	Inhibition of human salivary alpha-amylase	biolink:Association
DrugCentral:39	biolink:molecularly_interacts_with	UniProtKB:P04746	RO:0002436	drug_central	Mechanism of Action; CHEMBL2045; SINGLE PROTEIN	biolink:Association
DrugCentral:40	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:40	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:43	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:43	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:43	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:47	biolink:molecularly_interacts_with	UniProtKB:Q04760	RO:0002436	drug_central	Inhibition of glyoxalase 1	biolink:Association
DrugCentral:47	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:47	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:48	biolink:molecularly_interacts_with	UniProtKB:Q9BQB6	RO:0002436	drug_central		biolink:Association
DrugCentral:49	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central	Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligand	biolink:Association
DrugCentral:50	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assay	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:P20292	RO:0002436	drug_central	Inhibition of FLAP	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 catalytic domain by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 catalytic domain by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:P02144	RO:0002436	drug_central	Inhibition of myoglobin (unknown origin)-mediated arachidonic acid oxidation using [14C]AA as substrate after 3 hrs by GC/NICI/MS analysis	biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central		biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:Q8NER1	RO:0002436	drug_central		biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:52	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of recombinant human mitochondrial isozyme CA VA	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assay	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Ki value against human carbonic anhydrase VII	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 12 catalytic domain preincubated for 15 mins by CO2 hydration method	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 9 catalytic domain expressed in Escherichia coli by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human secreted carbonic anhydrase 4 measured by CO2 hydration reaction assay	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assay	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VB	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 13 preincubated for 15 mins by CO2 hydration method	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of full length human recombinant CA VI	biolink:Association
DrugCentral:56	biolink:molecularly_interacts_with	UniProtKB:P29972	RO:0002436	drug_central		biolink:Association
DrugCentral:57	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	displacement of [3H]glyburide binding in HEK-293 cells expressing hSUR1-hKir6.2	biolink:Association
DrugCentral:57	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	displacement of [3H]glyburide binding in HEK-293 cells expressing hSUR1-hKir6.2	biolink:Association
DrugCentral:58	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibitory activity against carbonic anhydrase II	biolink:Association
DrugCentral:59	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:60	biolink:molecularly_interacts_with	UniProtKB:P08473	RO:0002436	drug_central	Inhibition of human NEP-mediated amyloid beta hydrolysis	biolink:Association
DrugCentral:60	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central		biolink:Association
DrugCentral:62	biolink:molecularly_interacts_with	UniProtKB:P14061	RO:0002436	drug_central	Inhibition of human recombinant 17betaHSD1 expressed in HEK293 cells	biolink:Association
DrugCentral:62	biolink:molecularly_interacts_with	UniProtKB:P28845	RO:0002436	drug_central	Inhibition of human recombinant 11-beta-HSD1 expressed in HEK293 cells	biolink:Association
DrugCentral:62	biolink:molecularly_interacts_with	UniProtKB:P80365	RO:0002436	drug_central	Inhibition of human recombinant 11-beta-HSD2 expressed in HEK293 cells	biolink:Association
DrugCentral:62	biolink:molecularly_interacts_with	UniProtKB:P37059	RO:0002436	drug_central	Inhibition of human recombinant 17-beta-HSD2 expressed in HEK293 cells	biolink:Association
DrugCentral:65	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central	Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cells after 1.5 hrs by liquid scintillation counting	biolink:Association
DrugCentral:65	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Activation of M3-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal	biolink:Association
DrugCentral:65	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	Partial agonist activity at human 2:3 alpha4beta2 nAChR expressed in Xenopus laevis oocytes after 1 min by two electrode voltage clamp technique	biolink:Association
DrugCentral:65	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central	Partial agonist activity at human 2:3 alpha4beta2 nAChR expressed in Xenopus laevis oocytes after 1 min by two electrode voltage clamp technique	biolink:Association
DrugCentral:65	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	Activation of M5-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal	biolink:Association
DrugCentral:65	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Activation of M1-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signal	biolink:Association
DrugCentral:65	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:65	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:66	biolink:molecularly_interacts_with	UniProtKB:P04179	RO:0002436	drug_central		biolink:Association
DrugCentral:66	biolink:molecularly_interacts_with	UniProtKB:P15692	RO:0002436	drug_central		biolink:Association
DrugCentral:66	biolink:molecularly_interacts_with	UniProtKB:P99999	RO:0002436	drug_central		biolink:Association
DrugCentral:67	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:67	biolink:molecularly_interacts_with	UniProtKB:P05026	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:67	biolink:molecularly_interacts_with	UniProtKB:P13637	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:67	biolink:molecularly_interacts_with	UniProtKB:P14415	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:67	biolink:molecularly_interacts_with	UniProtKB:P50993	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:67	biolink:molecularly_interacts_with	UniProtKB:P54709	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:67	biolink:molecularly_interacts_with	UniProtKB:P54710	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:67	biolink:molecularly_interacts_with	UniProtKB:Q13733	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:73	biolink:molecularly_interacts_with	UniProtKB:P04156	RO:0002436	drug_central	Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cells	biolink:Association
DrugCentral:74	biolink:molecularly_interacts_with	UniProtKB:P19440	RO:0002436	drug_central	Inhibition of gamma-glutamyltranspeptidase by colorimetric assay	biolink:Association
DrugCentral:74	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:74	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:76	biolink:molecularly_interacts_with	UniProtKB:Q8TDS4	RO:0002436	drug_central		biolink:Association
DrugCentral:78	biolink:molecularly_interacts_with	UniProtKB:P10276	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:78	biolink:molecularly_interacts_with	UniProtKB:P13631	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:78	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:80	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:80	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central	Concentration inhibiting Clostridium histolyticum collagenase.	biolink:Association
DrugCentral:81	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:81	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:81	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:81	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:81	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:82	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:82	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:87	biolink:molecularly_interacts_with	UniProtKB:P10276	RO:0002436	drug_central	Binding affinity towards Retinoic acid receptor alpha	biolink:Association
DrugCentral:87	biolink:molecularly_interacts_with	UniProtKB:P13631	RO:0002436	drug_central	Binding affinity towards Retinoic acid receptor gamma	biolink:Association
DrugCentral:87	biolink:molecularly_interacts_with	UniProtKB:P10826	RO:0002436	drug_central	Binding affinity towards Retinoic acid receptor beta	biolink:Association
DrugCentral:87	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:88	biolink:molecularly_interacts_with	UniProtKB:P54098	RO:0002436	drug_central		biolink:Association
DrugCentral:89	biolink:molecularly_interacts_with	UniProtKB:P42356	RO:0002436	drug_central	Binding affinity (Ki) against human phosphatidylinositol 4-kinase	biolink:Association
DrugCentral:89	biolink:molecularly_interacts_with	UniProtKB:Q8TCG2	RO:0002436	drug_central	Binding affinity (Ki) against human phosphatidylinositol 4-kinase	biolink:Association
DrugCentral:89	biolink:molecularly_interacts_with	UniProtKB:Q9BTU6	RO:0002436	drug_central	Binding affinity (Ki) against human phosphatidylinositol 4-kinase	biolink:Association
DrugCentral:89	biolink:molecularly_interacts_with	UniProtKB:Q9UBF8	RO:0002436	drug_central	Binding affinity (Ki) against human phosphatidylinositol 4-kinase	biolink:Association
DrugCentral:89	biolink:molecularly_interacts_with	UniProtKB:P47989	RO:0002436	drug_central	Inhibition of human xanthine oxidase	biolink:Association
DrugCentral:90	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central		biolink:Association
DrugCentral:90	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central		biolink:Association
DrugCentral:90	biolink:molecularly_interacts_with	UniProtKB:P04406	RO:0002436	drug_central	Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyte	biolink:Association
DrugCentral:90	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central		biolink:Association
DrugCentral:90	biolink:molecularly_interacts_with	UniProtKB:P00813	RO:0002436	drug_central		biolink:Association
DrugCentral:90	biolink:molecularly_interacts_with	UniProtKB:P55263	RO:0002436	drug_central		biolink:Association
DrugCentral:90	biolink:molecularly_interacts_with	UniProtKB:P23526	RO:0002436	drug_central		biolink:Association
DrugCentral:90	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central		biolink:Association
DrugCentral:90	biolink:molecularly_interacts_with	UniProtKB:Q9BTU6	RO:0002436	drug_central		biolink:Association
DrugCentral:90	biolink:molecularly_interacts_with	UniProtKB:Q8TCG2	RO:0002436	drug_central		biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:P51575	RO:0002436	drug_central		biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:Q99571	RO:0002436	drug_central		biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:P41231	RO:0002436	drug_central		biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:Q9BPV8	RO:0002436	drug_central		biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:Q8TD43	RO:0002436	drug_central		biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:P56373	RO:0002436	drug_central		biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:Q13304	RO:0002436	drug_central		biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:Q12931	RO:0002436	drug_central	Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid from recombinant human Trap-1 after 24 hrs by fluorescence polarization assay	biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:Q96G91	RO:0002436	drug_central	Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluorescence assay	biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:P49137	RO:0002436	drug_central	Inhibition of human recombinant phospho-MK2 (36-400) by HTRF assay	biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:P51582	RO:0002436	drug_central	GRAC: human P2Y4 selective antagonist	biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:P47900	RO:0002436	drug_central	Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluorescence assay	biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:P11142	RO:0002436	drug_central	PUBCHEM_BIOASSAY: In Vitro Hsc70 Dose Response Fluorescence Polarization Assay. (Class of assay: confirmatory) [Related pubchem assays: 1072 ]	biolink:Association
DrugCentral:91	biolink:molecularly_interacts_with	UniProtKB:P0DMV8	RO:0002436	drug_central		biolink:Association
DrugCentral:92	biolink:molecularly_interacts_with	UniProtKB:Q8TD43	RO:0002436	drug_central		biolink:Association
DrugCentral:92	biolink:molecularly_interacts_with	UniProtKB:P09467	RO:0002436	drug_central	Inhibition of FBPase in human liver using fructose-2,6phosphate as a substrate	biolink:Association
DrugCentral:92	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Inhibition of p60c-src expressed in chick embryo fibroblast	biolink:Association
DrugCentral:92	biolink:molecularly_interacts_with	UniProtKB:O94759	RO:0002436	drug_central	Inhibition of TRPM2 (unknown origin)	biolink:Association
DrugCentral:92	biolink:molecularly_interacts_with	UniProtKB:P00338	RO:0002436	drug_central	Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by NMR analysis in presence of NADH	biolink:Association
DrugCentral:92	biolink:molecularly_interacts_with	UniProtKB:O43598	RO:0002436	drug_central		biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:P30536	RO:0002436	drug_central		biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:93	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:99	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:99	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:99	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:99	biolink:molecularly_interacts_with	UniProtKB:P48039	RO:0002436	drug_central	Binding affinity against ovine pars tuberalis melatonin receptor using 2-[125I]- melatonin radioligand binding assay	biolink:Association
DrugCentral:99	biolink:molecularly_interacts_with	UniProtKB:P49286	RO:0002436	drug_central	Binding affinity against ovine pars tuberalis melatonin receptor using 2-[125I]- melatonin radioligand binding assay	biolink:Association
DrugCentral:99	biolink:molecularly_interacts_with	UniProtKB:P48039	RO:0002436	drug_central	Binding affinity for human Melatonin receptor type 1A stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as radioligand	biolink:Association
DrugCentral:99	biolink:molecularly_interacts_with	UniProtKB:P49286	RO:0002436	drug_central	Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in HEK293 cells after 2 hrs by gamma counting	biolink:Association
DrugCentral:100	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:101	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:105	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:105	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:107	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:107	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:109	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central		biolink:Association
DrugCentral:111	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:111	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central	Agonist activity at mineralocorticoid receptor ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by luciferase reporter gene assay	biolink:Association
DrugCentral:111	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:112	biolink:molecularly_interacts_with	UniProtKB:P14324	RO:0002436	drug_central	Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 mins	biolink:Association
DrugCentral:113	biolink:molecularly_interacts_with	UniProtKB:Q9NR96	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Fluorescence-based cell-based high throughput dose response assay for inhibitors of TLR9-MyD88 binding. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504734, AID504750, AID540250, AID540251]	biolink:Association
DrugCentral:114	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:114	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:115	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Binding affinity against Alpha-1D adrenergic receptor, from human clones.	biolink:Association
DrugCentral:115	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding affinity against Alpha-1A adrenergic receptor from human clone	biolink:Association
DrugCentral:115	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Binding affinity against Alpha-1B adrenergic receptor from human clone	biolink:Association
DrugCentral:119	biolink:molecularly_interacts_with	UniProtKB:P00797	RO:0002436	drug_central		biolink:Association
DrugCentral:119	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:119	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:120	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:120	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:124	biolink:molecularly_interacts_with	UniProtKB:P47989	RO:0002436	drug_central	Inhibitory activity against Xanthine Oxidase	biolink:Association
DrugCentral:124	biolink:molecularly_interacts_with	UniProtKB:P00492	RO:0002436	drug_central		biolink:Association
DrugCentral:128	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:128	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:128	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:129	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:129	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:129	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Binding affinity to human HT3A receptor	biolink:Association
DrugCentral:129	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG expressed in HEK cells by patch clamp technique	biolink:Association
DrugCentral:130	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:130	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central		biolink:Association
DrugCentral:133	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:133	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:133	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:133	biolink:molecularly_interacts_with	UniProtKB:P30531	RO:0002436	drug_central		biolink:Association
DrugCentral:133	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:133	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:133	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:134	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P25105	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:O60885	RO:0002436	drug_central	Binding affinity to BRD4-BD1 by isothermal titration calorimetry	biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:136	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:137	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:137	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	Displacement of [3H]-CGP 12177 from human beta-3 adrenergic receptor expressed in CHOK1 cells	biolink:Association
DrugCentral:137	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	radioligand  [3H]CGP12177  0.15nM competition binding; human recombinant beta-adrenoreceptors in Sf9 cells	biolink:Association
DrugCentral:137	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	radioligand  [3H]CGP12177  0.15nM competition binding; human recombinant beta-adrenoceptors in Sf9 cells	biolink:Association
DrugCentral:138	biolink:molecularly_interacts_with	UniProtKB:Q7RTX7	RO:0002436	drug_central	Patch clamp electrophysiology.	biolink:Association
DrugCentral:138	biolink:molecularly_interacts_with	UniProtKB:Q86XQ3	RO:0002436	drug_central	Patch clamp electrophysiology.	biolink:Association
DrugCentral:138	biolink:molecularly_interacts_with	UniProtKB:Q8NEC5	RO:0002436	drug_central	Patch clamp electrophysiology	biolink:Association
DrugCentral:138	biolink:molecularly_interacts_with	UniProtKB:Q96P56	RO:0002436	drug_central	Patch clamp electrophysiology.	biolink:Association
DrugCentral:138	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central		biolink:Association
DrugCentral:138	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central		biolink:Association
DrugCentral:138	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:138	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:138	biolink:molecularly_interacts_with	UniProtKB:Q13258	RO:0002436	drug_central		biolink:Association
DrugCentral:138	biolink:molecularly_interacts_with	UniProtKB:P43119	RO:0002436	drug_central		biolink:Association
DrugCentral:141	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:143	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:143	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Displacement of [3H]diprenorphine from human cloned kappa opioid receptor	biolink:Association
DrugCentral:143	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Displacement of [3H]diprenorphine from human cloned delta opioid receptor	biolink:Association
DrugCentral:144	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity towards sigma receptor in guinea pig brain membrane was determined by using [3H]DTG as the radioligand	biolink:Association
DrugCentral:144	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:144	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:144	biolink:molecularly_interacts_with	UniProtKB:O60391	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:144	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:144	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:144	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:144	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:144	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:146	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Mechanism of Action; CHEMBL220; SINGLE PROTEIN	biolink:Association
DrugCentral:147	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:147	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:147	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central		biolink:Association
DrugCentral:147	biolink:molecularly_interacts_with	UniProtKB:P04062	RO:0002436	drug_central	Inhibition of beta-glucocerebrosidase in human fibroblast lysate using 4-methylumbelliferyl beta-D-glycopyranoside as substrate by fluorimetric analysis	biolink:Association
DrugCentral:150	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:156	biolink:molecularly_interacts_with	UniProtKB:P05186	RO:0002436	drug_central		biolink:Association
DrugCentral:156	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:Q16515	RO:0002436	drug_central		biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:P37088	RO:0002436	drug_central	GRAC: human ENaC blocker	biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:P51168	RO:0002436	drug_central	GRAC: human ENaC blocker	biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:P51170	RO:0002436	drug_central	GRAC: human ENaC blocker	biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:P37088	RO:0002436	drug_central	Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assay	biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:P78348	RO:0002436	drug_central	GRAC: human ASIC1 blocker	biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:Q9UHC3	RO:0002436	drug_central	Inhibition of ASIC3 assessed as inhibition of peak current by patch clamp electrophysiology	biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:P19634	RO:0002436	drug_central	Inhibition of human wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride prepulse protocol	biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central		biolink:Association
DrugCentral:158	biolink:molecularly_interacts_with	UniProtKB:P00749	RO:0002436	drug_central		biolink:Association
DrugCentral:163	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central	Binding affinity to full length Glu-plasminogen in human plasma assessed as inhibition of interaction with fibrin in presence of tPA	biolink:Association
DrugCentral:163	biolink:molecularly_interacts_with	UniProtKB:P00750	RO:0002436	drug_central		biolink:Association
DrugCentral:164	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central		biolink:Association
DrugCentral:164	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	Inhibition of Thromboxane-A synthase	biolink:Association
DrugCentral:164	biolink:molecularly_interacts_with	UniProtKB:P05108	RO:0002436	drug_central	Mechanism of Action; CHEMBL2033; SINGLE PROTEIN	biolink:Association
DrugCentral:165	biolink:molecularly_interacts_with	UniProtKB:Q4U2R8	RO:0002436	drug_central	Inhibition of human Oat1 expressed in Drosophila S2 cells	biolink:Association
DrugCentral:171	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:171	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:174	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	Inhibition of human MMP-9 after 60 mins by FRET assay	biolink:Association
DrugCentral:174	biolink:molecularly_interacts_with	UniProtKB:P03956	RO:0002436	drug_central	Inhibition of human MMP-1 after 60 mins by FRET assay	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central	DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P41597	RO:0002436	drug_central	DRUGMATRIX: Chemokine CCR2B  radioligand binding (ligand: [125I] MCP-1)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P30411	RO:0002436	drug_central	DRUGMATRIX: Bradykinin B2 radioligand binding (ligand: [3H] Bradykinin)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P41968	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P51679	RO:0002436	drug_central	DRUGMATRIX: Chemokine CCR4 radioligand binding (ligand: [125I] TARC)	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P10828	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P10827	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:Q96RP8	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:Q9NVV9	RO:0002436	drug_central		biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:Q14534	RO:0002436	drug_central	Inhibitory activity against Trypanosoma cruzi microsomal squalene synthase	biolink:Association
DrugCentral:176	biolink:molecularly_interacts_with	UniProtKB:P37268	RO:0002436	drug_central	Inhibitory activity against Trypanosoma cruzi glycosomal squalene synthase	biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:179	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Inhibition of human NaV1.5 alpha subunit expressed in CHOK1 cells at -90 mV holding potential by patch clamp electrophysiological assay	biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cells preincubated for 10 mins prior to substrate addition measured after 4 mins by FLIPR assay	biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assay	biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of human NaV1.2 alpha subunit expressed in CHOK1 cells at -65 mV holding potential by patch clamp electrophysiological assay	biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central		biolink:Association
DrugCentral:180	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central		biolink:Association
DrugCentral:181	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central		biolink:Association
DrugCentral:182	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093863; PROTEIN FAMILY	biolink:Association
DrugCentral:182	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093863; PROTEIN FAMILY	biolink:Association
DrugCentral:182	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093863; PROTEIN FAMILY	biolink:Association
DrugCentral:182	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093863; PROTEIN FAMILY	biolink:Association
DrugCentral:182	biolink:molecularly_interacts_with	UniProtKB:Q14164	RO:0002436	drug_central	Inhibition of substrate phosphorylation.	biolink:Association
DrugCentral:182	biolink:molecularly_interacts_with	UniProtKB:Q9UHD2	RO:0002436	drug_central	Inhibition of substrate phosphorylation.	biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central		biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:Q06432	RO:0002436	drug_central		biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central		biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Binding affinity against human Alpha-1d adrenergic receptor	biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:O95069	RO:0002436	drug_central	Inhibition of TREK-1 (unknown origin)	biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding affinity against human Alpha-1a adrenergic receptor	biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Binding affinity against human Alpha-1b adrenergic receptor	biolink:Association
DrugCentral:183	biolink:molecularly_interacts_with	UniProtKB:P54289	RO:0002436	drug_central		biolink:Association
DrugCentral:186	biolink:molecularly_interacts_with	UniProtKB:Q9Y251	RO:0002436	drug_central	Binding affinity to recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance assay	biolink:Association
DrugCentral:186	biolink:molecularly_interacts_with	UniProtKB:P50135	RO:0002436	drug_central	Inhibition of histamine N-methyltransferase by radiochemical assay	biolink:Association
DrugCentral:186	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human cloned ERG	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT3 radioligand binding (ligand: [3H] GR-65630)	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Displacement of [3H]-YM09151-2 from human cloned dopamine D4 receptor expressed in insect Sf9 cells after 60 mins by liquid scintillation counting	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHO cells after 60 mins by liquid scintillation counting	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 7 receptor	biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:Q9Y345	RO:0002436	drug_central		biolink:Association
DrugCentral:191	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:192	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:192	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:192	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:193	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:193	biolink:molecularly_interacts_with	UniProtKB:O00519	RO:0002436	drug_central	Inhibition of human FAAH-mediated hydrolysis of [3H]AEA	biolink:Association
DrugCentral:195	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central	(S) enantiomer activation of hTAAR1 in RD-HGA16 cells	biolink:Association
DrugCentral:195	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Mechanism of Action; CHEMBL222; SINGLE PROTEIN	biolink:Association
DrugCentral:195	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:195	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:195	biolink:molecularly_interacts_with	UniProtKB:Q16568	RO:0002436	drug_central		biolink:Association
DrugCentral:195	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:195	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:198	biolink:molecularly_interacts_with	UniProtKB:Q8TD43	RO:0002436	drug_central	GRAC: human TRPM4 blocker	biolink:Association
DrugCentral:198	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding affinity to human recombinant Tie2 by SPR assay	biolink:Association
DrugCentral:200	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:200	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:200	biolink:molecularly_interacts_with	UniProtKB:P07339	RO:0002436	drug_central	Inhibition of human cathepsin D	biolink:Association
DrugCentral:201	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central		biolink:Association
DrugCentral:201	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of canine heart Phosphodiesterase 4	biolink:Association
DrugCentral:201	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibition of canine heart Phosphodiesterase 4	biolink:Association
DrugCentral:201	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Inhibition of canine heart Phosphodiesterase 4	biolink:Association
DrugCentral:201	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of canine heart Phosphodiesterase 4	biolink:Association
DrugCentral:201	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central		biolink:Association
DrugCentral:203	biolink:molecularly_interacts_with	UniProtKB:Q969P6	RO:0002436	drug_central		biolink:Association
DrugCentral:203	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:203	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central	Inhibition of human DNA topoisomerase 2-mediated Crithidia fasciculata kDNA decatenation using ethidium bromide staining by agarose gel electrophoresis	biolink:Association
DrugCentral:203	biolink:molecularly_interacts_with	UniProtKB:Q02880	RO:0002436	drug_central	Inhibition of calf thymus DNA/ethidium bromide complex formation.	biolink:Association
DrugCentral:203	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central	Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assay	biolink:Association
DrugCentral:203	biolink:molecularly_interacts_with	UniProtKB:Q02880	RO:0002436	drug_central	Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assay	biolink:Association
DrugCentral:203	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG potassium channel	biolink:Association
DrugCentral:203	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:203	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central		biolink:Association
DrugCentral:209	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central		biolink:Association
DrugCentral:209	biolink:molecularly_interacts_with	UniProtKB:O00408	RO:0002436	drug_central	Inhibition of human platelet PDE by inhibiting cyclic Guanosine monophosphate (cGMP) hydrolysis	biolink:Association
DrugCentral:210	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central		biolink:Association
DrugCentral:213	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:214	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Binding affinity at human recombinant ERalpha	biolink:Association
DrugCentral:214	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:214	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Binding affinity at human recombinant ERbeta	biolink:Association
DrugCentral:214	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Binding affinity at AR	biolink:Association
DrugCentral:214	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:215	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Binding affinity for aromatase cytochrome P45019A1 by analysis of Dixon plot	biolink:Association
DrugCentral:215	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:215	biolink:molecularly_interacts_with	UniProtKB:P37058	RO:0002436	drug_central	Ability to inhibit the Type-3 17-beta- hydroxysteroid dehydrogenase activity transfected in human embryonic kidney (HEK)-293 cells experiment 3	biolink:Association
DrugCentral:215	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:217	biolink:molecularly_interacts_with	UniProtKB:P05121	RO:0002436	drug_central		biolink:Association
DrugCentral:219	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central		biolink:Association
DrugCentral:219	biolink:molecularly_interacts_with	UniProtKB:Q5T3U5	RO:0002436	drug_central		biolink:Association
DrugCentral:219	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:219	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:219	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:220	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:222	biolink:molecularly_interacts_with	UniProtKB:P38435	RO:0002436	drug_central		biolink:Association
DrugCentral:223	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:223	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:224	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action; CHEMBL231; SINGLE PROTEIN	biolink:Association
DrugCentral:226	biolink:molecularly_interacts_with	UniProtKB:O75342	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Displacement of [3H]domperidone from human cloned dopamine D3 receptor expressed in mouse CCL1-3 cells by scintillation counting	biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cells	biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Binding affinity to dopamine D1 receptor high binding site by radioligand displacement assay	biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membrane	biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]8-OH-DPAT	biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:O75762	RO:0002436	drug_central	Calcium imaging, patch clamp	biolink:Association
DrugCentral:228	biolink:molecularly_interacts_with	UniProtKB:P34949	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate. (Class of assay: confirmatory) [Related pubchem assays: 1209 ]	biolink:Association
DrugCentral:229	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:229	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Compound was tested in vitro for binding affinity against Alpha-2C adrenergic receptor from cloned human C-2 receptor transfected into Chinese hamster ovary (CHO) cells	biolink:Association
DrugCentral:229	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Compound was tested for binding affinity based on dissociation constant of Alpha-1 adrenergic receptor	biolink:Association
DrugCentral:229	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Compound was tested for binding affinity based on dissociation constant of Alpha-1 adrenergic receptor	biolink:Association
DrugCentral:229	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Compound was tested for binding affinity based on dissociation constant of Alpha-1 adrenergic receptor	biolink:Association
DrugCentral:229	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamster ovary (CHO) cells	biolink:Association
DrugCentral:230	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:230	biolink:molecularly_interacts_with	UniProtKB:P29371	RO:0002436	drug_central	Displacement of [3H]osanetant from wild type human NK3 receptor expressed in HEK293 cells	biolink:Association
DrugCentral:230	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	GRAC: human NK1 selective antagonist	biolink:Association
DrugCentral:231	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:231	biolink:molecularly_interacts_with	UniProtKB:P32418	RO:0002436	drug_central		biolink:Association
DrugCentral:231	biolink:molecularly_interacts_with	UniProtKB:P25786	RO:0002436	drug_central		biolink:Association
DrugCentral:231	biolink:molecularly_interacts_with	UniProtKB:P0DP23	RO:0002436	drug_central		biolink:Association
DrugCentral:231	biolink:molecularly_interacts_with	UniProtKB:P0DP24	RO:0002436	drug_central		biolink:Association
DrugCentral:231	biolink:molecularly_interacts_with	UniProtKB:P0DP25	RO:0002436	drug_central		biolink:Association
DrugCentral:231	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:231	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:231	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:234	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:234	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:237	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:239	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central		biolink:Association
DrugCentral:239	biolink:molecularly_interacts_with	UniProtKB:P00750	RO:0002436	drug_central	Inhibition of human t-PA	biolink:Association
DrugCentral:239	biolink:molecularly_interacts_with	UniProtKB:P00742	RO:0002436	drug_central	Inhibition of human factor 10a	biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of human ABCB1-mediated rhodamine 123 efflux in mouse L5178 cells expressing human MDR1 after 20 mins by FACS analysis	biolink:Association
DrugCentral:242	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Displacement of [3H]dofetilide from human ERG	biolink:Association
DrugCentral:244	biolink:molecularly_interacts_with	UniProtKB:Q16881	RO:0002436	drug_central	Mechanism of Action; CHEMBL1927; SINGLE PROTEIN	biolink:Association
DrugCentral:244	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:O95259	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT3 radioligand binding (ligand: [3H] GR-65630)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P41968	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P0DP23	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P0DP24	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P0DP25	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central	Displacement of [3H]histamine from human H4R expressed in Sf9 cells co-expressing RGS19, Galphai2 and Gbeta1gamma2 after 60 mins by liquid scintillation counting	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P35346	RO:0002436	drug_central	Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:O75530	RO:0002436	drug_central		biolink:Association
DrugCentral:249	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:252	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central		biolink:Association
DrugCentral:254	biolink:molecularly_interacts_with	UniProtKB:P22309	RO:0002436	drug_central		biolink:Association
DrugCentral:254	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central		biolink:Association
DrugCentral:254	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:254	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:254	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of human MDR1-dependent accumulation of calcein-AM expressed in MDCK2 cells	biolink:Association
DrugCentral:255	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:255	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:255	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT	biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporter	biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG expressed in HEK293 cells by patch-clamp method	biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Equilibrium dissociation constant (KD) for Competitive binding between [3H]- imipramine and the compound at human transporter-hSERT	biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:P48051	RO:0002436	drug_central		biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:P48549	RO:0002436	drug_central		biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:P48544	RO:0002436	drug_central		biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:P48549	RO:0002436	drug_central		biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:P48051	RO:0002436	drug_central		biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:256	biolink:molecularly_interacts_with	UniProtKB:Q13118	RO:0002436	drug_central		biolink:Association
DrugCentral:257	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central		biolink:Association
DrugCentral:257	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:257	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	Inhibition of CYP3A4 in human liver microsome	biolink:Association
DrugCentral:257	biolink:molecularly_interacts_with	UniProtKB:Q9UBN7	RO:0002436	drug_central	Inhibition of recombinant HDAC6 (unknown origin) after 10 mins by fluorimetric analysis	biolink:Association
DrugCentral:257	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central	Inhibition of recombinant HDAC1 (unknown origin) after 10 mins by fluorimetric analysis	biolink:Association
DrugCentral:257	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central	Inhibition of recombinant HDAC2 (unknown origin) after 10 mins by fluorimetric analysis	biolink:Association
DrugCentral:258	biolink:molecularly_interacts_with	UniProtKB:Q02127	RO:0002436	drug_central		biolink:Association
DrugCentral:259	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:259	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:259	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:259	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:260	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:260	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:260	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:260	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:260	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:260	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:260	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:260	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:260	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:260	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:266	biolink:molecularly_interacts_with	UniProtKB:P47989	RO:0002436	drug_central		biolink:Association
DrugCentral:266	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:267	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:268	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:269	biolink:molecularly_interacts_with	UniProtKB:P51580	RO:0002436	drug_central		biolink:Association
DrugCentral:269	biolink:molecularly_interacts_with	UniProtKB:P63000	RO:0002436	drug_central		biolink:Association
DrugCentral:269	biolink:molecularly_interacts_with	UniProtKB:O15439	RO:0002436	drug_central		biolink:Association
DrugCentral:269	biolink:molecularly_interacts_with	UniProtKB:O15440	RO:0002436	drug_central		biolink:Association
DrugCentral:269	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:270	biolink:molecularly_interacts_with	UniProtKB:P31213	RO:0002436	drug_central		biolink:Association
DrugCentral:271	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:271	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:271	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding affinity to human adrenergic alpha1A receptor expressed in rat intact fibroblasts	biolink:Association
DrugCentral:271	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Binding affinity to human adrenergic Alpha-1B receptor expressed in rat intact fibroblasts	biolink:Association
DrugCentral:271	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Displacement of labeled dofetilide human ERG	biolink:Association
DrugCentral:271	biolink:molecularly_interacts_with	UniProtKB:Q9Y5N1	RO:0002436	drug_central	Antagonist activity at human H3 receptor expressed in CHO cells assessed as inhibition of histamine-induced GTPgamma[S] binding by scintillation proximity assay	biolink:Association
DrugCentral:272	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:272	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:274	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against IKr potassium channel	biolink:Association
DrugCentral:276	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:276	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:276	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:276	biolink:molecularly_interacts_with	UniProtKB:O43193	RO:0002436	drug_central		biolink:Association
DrugCentral:281	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:281	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:282	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:282	biolink:molecularly_interacts_with	UniProtKB:O75899	RO:0002436	drug_central	Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum	biolink:Association
DrugCentral:282	biolink:molecularly_interacts_with	UniProtKB:Q9UBS5	RO:0002436	drug_central	Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum	biolink:Association
DrugCentral:284	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:284	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:284	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central	Mechanism of Action; CHEMBL215; SINGLE PROTEIN	biolink:Association
DrugCentral:284	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Mechanism of Action; CHEMBL235; SINGLE PROTEIN	biolink:Association
DrugCentral:285	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:285	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:285	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central		biolink:Association
DrugCentral:285	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central		biolink:Association
DrugCentral:288	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:290	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:290	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:294	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:294	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:294	biolink:molecularly_interacts_with	UniProtKB:P05113	RO:0002436	drug_central	Inhibition of interleukin-5	biolink:Association
DrugCentral:296	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central		biolink:Association
DrugCentral:299	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central		biolink:Association
DrugCentral:302	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central		biolink:Association
DrugCentral:302	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central		biolink:Association
DrugCentral:302	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central		biolink:Association
DrugCentral:302	biolink:molecularly_interacts_with	UniProtKB:Q969S8	RO:0002436	drug_central		biolink:Association
DrugCentral:302	biolink:molecularly_interacts_with	UniProtKB:Q9BY41	RO:0002436	drug_central		biolink:Association
DrugCentral:302	biolink:molecularly_interacts_with	UniProtKB:Q9UBN7	RO:0002436	drug_central		biolink:Association
DrugCentral:305	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central		biolink:Association
DrugCentral:305	biolink:molecularly_interacts_with	UniProtKB:Q12791	RO:0002436	drug_central		biolink:Association
DrugCentral:305	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central		biolink:Association
DrugCentral:305	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central		biolink:Association
DrugCentral:305	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:311	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:312	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:312	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:312	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:312	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:312	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:312	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:313	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:314	biolink:molecularly_interacts_with	UniProtKB:P20711	RO:0002436	drug_central		biolink:Association
DrugCentral:314	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Estrogen Receptor-beta Coactivator Binding Inhibitors ELISA Secondary Assay. (Class of assay: confirmatory) [Related pubchem assays: 633 (Primary screen preceding this ELISA dose response confirmation assay.), 733 (Primary dose response assay preceding this ELISA dose response confirmation assay.)]	biolink:Association
DrugCentral:314	biolink:molecularly_interacts_with	UniProtKB:Q9UBE0	RO:0002436	drug_central	PUBCHEM_BIOASSAY: uHTS HTRF assay for identification of inhibitors of SUMOylation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2011, AID2018, AID2069, AID2614, AID2658]	biolink:Association
DrugCentral:314	biolink:molecularly_interacts_with	UniProtKB:Q9UBT2	RO:0002436	drug_central	PUBCHEM_BIOASSAY: uHTS HTRF assay for identification of inhibitors of SUMOylation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2011, AID2018, AID2069, AID2614, AID2658]	biolink:Association
DrugCentral:317	biolink:molecularly_interacts_with	UniProtKB:Q96S37	RO:0002436	drug_central	Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation counting	biolink:Association
DrugCentral:318	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:318	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:318	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:318	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP)	biolink:Association
DrugCentral:318	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:318	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:318	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central	Inhibition of human MRP1 expressed in Spodoptera frugiperda Sf9 cells assessed as inhibition of NEM-GS-induced vanadate-sensitive ATPase activity measured by generation of inorganic phosphate by spectrophotometry in presence of glutathione	biolink:Association
DrugCentral:318	biolink:molecularly_interacts_with	UniProtKB:Q04828	RO:0002436	drug_central	Inhibition of 20-alpha HSD	biolink:Association
DrugCentral:318	biolink:molecularly_interacts_with	UniProtKB:Q96S37	RO:0002436	drug_central	Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation counting	biolink:Association
DrugCentral:321	biolink:molecularly_interacts_with	UniProtKB:O15392	RO:0002436	drug_central	Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins	biolink:Association
DrugCentral:323	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:323	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:323	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:323	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:323	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:323	biolink:molecularly_interacts_with	UniProtKB:Q01118	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:323	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:323	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:323	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:323	biolink:molecularly_interacts_with	UniProtKB:Q9UI33	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:326	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:329	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Mechanism of Action; CHEMBL222; SINGLE PROTEIN	biolink:Association
DrugCentral:329	biolink:molecularly_interacts_with	UniProtKB:Q05940	RO:0002436	drug_central	Mechanism of Action; CHEMBL1893; SINGLE PROTEIN	biolink:Association
DrugCentral:329	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:329	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:331	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:331	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:331	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:331	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:331	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:331	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:331	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:332	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central		biolink:Association
DrugCentral:332	biolink:molecularly_interacts_with	UniProtKB:Q12791	RO:0002436	drug_central		biolink:Association
DrugCentral:332	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central		biolink:Association
DrugCentral:332	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central		biolink:Association
DrugCentral:332	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Binding affinity of [3H]citalopram for serotonin transporter in monkey	biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:333	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:341	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:O00555	RO:0002436	drug_central		biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:P56696	RO:0002436	drug_central		biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:342	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:343	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central		biolink:Association
DrugCentral:343	biolink:molecularly_interacts_with	UniProtKB:P43119	RO:0002436	drug_central		biolink:Association
DrugCentral:343	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:346	biolink:molecularly_interacts_with	UniProtKB:Q9Y5N1	RO:0002436	drug_central	[125I]Iodoproxyfan binding to H3 receptors in CHO cells	biolink:Association
DrugCentral:348	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:348	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:349	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:351	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:353	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:354	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:355	biolink:molecularly_interacts_with	UniProtKB:Q8TCC7	RO:0002436	drug_central		biolink:Association
DrugCentral:355	biolink:molecularly_interacts_with	UniProtKB:Q4U2R8	RO:0002436	drug_central		biolink:Association
DrugCentral:356	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:356	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:357	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:358	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:358	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:358	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:358	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:359	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:360	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:361	biolink:molecularly_interacts_with	UniProtKB:P19793	RO:0002436	drug_central	Inhibition of [3H]9-cis-RA binding to baculovirus expressed retinoid receptor RXR alpha	biolink:Association
DrugCentral:361	biolink:molecularly_interacts_with	UniProtKB:P28702	RO:0002436	drug_central	Selective activity towards retinoid X receptor-beta	biolink:Association
DrugCentral:361	biolink:molecularly_interacts_with	UniProtKB:P48443	RO:0002436	drug_central	Selective activity towards retinoid X receptor-gamma	biolink:Association
DrugCentral:361	biolink:molecularly_interacts_with	UniProtKB:P10826	RO:0002436	drug_central	Selective activity towards retinoic acid receptor-beta	biolink:Association
DrugCentral:361	biolink:molecularly_interacts_with	UniProtKB:P10276	RO:0002436	drug_central	Selective activity towards retinoic acid receptor-alpha	biolink:Association
DrugCentral:361	biolink:molecularly_interacts_with	UniProtKB:P13631	RO:0002436	drug_central	Selective activity towards retinoic acid receptor-gamma	biolink:Association
DrugCentral:361	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Measured using a TR-FRET competitive displacement assay.	biolink:Association
DrugCentral:362	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central		biolink:Association
DrugCentral:362	biolink:molecularly_interacts_with	UniProtKB:P06858	RO:0002436	drug_central		biolink:Association
DrugCentral:362	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central		biolink:Association
DrugCentral:362	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central	Agonist activity at human PPARdelta expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay	biolink:Association
DrugCentral:362	biolink:molecularly_interacts_with	UniProtKB:P12104	RO:0002436	drug_central	Displacement of 1-anilinonaphthalene-8-sulphonic acid from I-FABP	biolink:Association
DrugCentral:362	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central		biolink:Association
DrugCentral:367	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Inhibition of human AR	biolink:Association
DrugCentral:367	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:369	biolink:molecularly_interacts_with	UniProtKB:Q9Y468	RO:0002436	drug_central	Inhibition of L3MBTL1 by alpha-screening	biolink:Association
DrugCentral:370	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay	biolink:Association
DrugCentral:370	biolink:molecularly_interacts_with	UniProtKB:P05093	RO:0002436	drug_central	In vitro inhibition of human Cytochrome P450 17A1 activity	biolink:Association
DrugCentral:370	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central		biolink:Association
DrugCentral:371	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central		biolink:Association
DrugCentral:373	biolink:molecularly_interacts_with	UniProtKB:P14735	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Counterscreen for IDE activators: Fluorescence polarization-based biochemical high throughput dose response assay for activators of recombinant IDE. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493087, AID493124, AID588439, AID588440, AID588442]	biolink:Association
DrugCentral:374	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:374	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:374	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:374	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:374	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:374	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:375	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:375	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:375	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:376	biolink:molecularly_interacts_with	UniProtKB:P15559	RO:0002436	drug_central	Inhibition of human recombinant NQO1	biolink:Association
DrugCentral:380	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:380	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:380	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:383	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:384	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Mechanism of Action; CHEMBL210; SINGLE PROTEIN	biolink:Association
DrugCentral:385	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central		biolink:Association
DrugCentral:388	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:388	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:388	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:388	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:389	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:389	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:389	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:389	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:389	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:389	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:389	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P25786	RO:0002436	drug_central		biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central		biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:A5PKW4	RO:0002436	drug_central		biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	Inhibitory activity against thrombin	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P08311	RO:0002436	drug_central	Inhibitory activity against human cathepsin G	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P10619	RO:0002436	drug_central	Inhibition of recombinant cathepsin A (unknown origin) using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH as substrate incubated with enzyme for 5 mins prior to substrate challenge for 2 hrs by spectrofluorometer analysis	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P23946	RO:0002436	drug_central	Inhibition of human chymase	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P17538	RO:0002436	drug_central	Inhibitory activity against human Chymotrypsinogen	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P20618	RO:0002436	drug_central	Reversible inhibition of human erythrocyte derived 20S proteasome subunit beta1 after 30 mins by fluorogenic assay	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P28074	RO:0002436	drug_central	Inhibition of 20S proteasome beta5 subunit (unknown origin) assessed as formation of reversible adduct with N-terminal threonine	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P49721	RO:0002436	drug_central	Reversible inhibition of human erythrocyte derived 20S proteasome subunit beta2 after 30 mins by fluorogenic assay	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P19838	RO:0002436	drug_central	Inhibition of NFkappaB in HEK293 cells incubated for 1 hr prior to TNF-alpha challenge measured after 3 hrs by luciferase reporter gene assay relative to control	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:Q00653	RO:0002436	drug_central	Inhibition of NFkappaB in HEK293 cells incubated for 1 hr prior to TNF-alpha challenge measured after 3 hrs by luciferase reporter gene assay relative to control	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:Q04206	RO:0002436	drug_central	Inhibition of NFkappaB in HEK293 cells incubated for 1 hr prior to TNF-alpha challenge measured after 3 hrs by luciferase reporter gene assay relative to control	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P28062	RO:0002436	drug_central	Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:P08246	RO:0002436	drug_central	Inhibitory activity against human leukocyte elastase	biolink:Association
DrugCentral:391	biolink:molecularly_interacts_with	UniProtKB:Q99460	RO:0002436	drug_central		biolink:Association
DrugCentral:392	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:392	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central	Ability to displace endothelin ([125I]ET1) from human Endothelin A receptor	biolink:Association
DrugCentral:392	biolink:molecularly_interacts_with	UniProtKB:P24530	RO:0002436	drug_central	Inhibitory activity against human endothelin B receptor expressed in CHO cells	biolink:Association
DrugCentral:392	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:394	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Mechanism of Action; CHEMBL222; SINGLE PROTEIN	biolink:Association
DrugCentral:394	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:394	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:395	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:395	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:395	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:395	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:395	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:395	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:395	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 2 by dansylamide (DNSA) competition assay	biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibitory activity against catalytic domain of human carbonic anhydrase XII	biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human full length carbonic anhydrase 4 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human carbonic anhydrase13 preincubated for 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VA	biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay	biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Ki value against human carbonic anhydrase VII	biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase9 preincubated for 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Compound was evaluated for binding affinity against human carbonic anhydrase II (hCA -II)	biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VB	biolink:Association
DrugCentral:396	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of full length human recombinant CA VI	biolink:Association
DrugCentral:397	biolink:molecularly_interacts_with	UniProtKB:P04183	RO:0002436	drug_central	Binding affinity constant against HSV-1 thymidine kinase	biolink:Association
DrugCentral:399	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:399	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:399	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:401	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:401	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:402	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:402	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:402	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:403	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:404	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:406	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central		biolink:Association
DrugCentral:406	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:407	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:408	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:408	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:408	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:408	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:408	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:409	biolink:molecularly_interacts_with	UniProtKB:P25105	RO:0002436	drug_central	In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.	biolink:Association
DrugCentral:416	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action; CHEMBL231; SINGLE PROTEIN	biolink:Association
DrugCentral:419	biolink:molecularly_interacts_with	UniProtKB:P01579	RO:0002436	drug_central		biolink:Association
DrugCentral:419	biolink:molecularly_interacts_with	UniProtKB:P05113	RO:0002436	drug_central		biolink:Association
DrugCentral:419	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:419	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:419	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:419	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:419	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:420	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:420	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:420	biolink:molecularly_interacts_with	UniProtKB:O60391	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:420	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:420	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:420	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:420	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:420	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:422	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central	Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand	biolink:Association
DrugCentral:422	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand	biolink:Association
DrugCentral:422	biolink:molecularly_interacts_with	UniProtKB:Q06432	RO:0002436	drug_central		biolink:Association
DrugCentral:422	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:422	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:422	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:422	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:422	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:424	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:424	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:424	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:424	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:427	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central		biolink:Association
DrugCentral:427	biolink:molecularly_interacts_with	UniProtKB:Q13621	RO:0002436	drug_central		biolink:Association
DrugCentral:427	biolink:molecularly_interacts_with	UniProtKB:P55011	RO:0002436	drug_central		biolink:Association
DrugCentral:427	biolink:molecularly_interacts_with	UniProtKB:Q9HC97	RO:0002436	drug_central		biolink:Association
DrugCentral:429	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:429	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:429	biolink:molecularly_interacts_with	UniProtKB:P16083	RO:0002436	drug_central		biolink:Association
DrugCentral:429	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:431	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:431	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:431	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:431	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:431	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:431	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:432	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central		biolink:Association
DrugCentral:432	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central		biolink:Association
DrugCentral:432	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:432	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of wild-type human ERG channel expressed in CHO cells by whole-cell patch clamp technique	biolink:Association
DrugCentral:432	biolink:molecularly_interacts_with	UniProtKB:Q9UK17	RO:0002436	drug_central		biolink:Association
DrugCentral:432	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:432	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:432	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:432	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:433	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:433	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:433	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:434	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:434	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:434	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:434	biolink:molecularly_interacts_with	UniProtKB:P41146	RO:0002436	drug_central	Displacement of [3H]-N/OFQ from human nociceptin opioid receptor transfected in CHO cells after 60 mins by beta-plate liquid scintillation counting analysis	biolink:Association
DrugCentral:434	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central	Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7	biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2	biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central	Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2	biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central	Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta4	biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central	Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta4	biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Displacement of [125I]RTI55 from cloned human NET expressed in HEK293 cells	biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:435	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:436	biolink:molecularly_interacts_with	UniProtKB:P22888	RO:0002436	drug_central		biolink:Association
DrugCentral:436	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central		biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Inhibition of [3H]spiperone binding to Dopamine receptor D3 in bovine cortex	biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:437	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:438	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:439	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:439	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:439	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:441	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:441	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:441	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:444	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:444	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:444	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:444	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:444	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:444	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:454	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cell membrane	biolink:Association
DrugCentral:454	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Displacement of [3H]Naltindole from human delta opioid receptor expressed in CHO cell membrane	biolink:Association
DrugCentral:454	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Displacement of [3H]DAMGO form human mu opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:455	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:455	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:455	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:458	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:458	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:458	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:458	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:460	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Displacement of [125I](+/-)DOI from human 5-HT2B receptor transfected in CHO cell membrane after 60 mins by scintillation counting analysis	biolink:Association
DrugCentral:461	biolink:molecularly_interacts_with	UniProtKB:P05164	RO:0002436	drug_central		biolink:Association
DrugCentral:461	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:463	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central		biolink:Association
DrugCentral:463	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central		biolink:Association
DrugCentral:463	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central		biolink:Association
DrugCentral:463	biolink:molecularly_interacts_with	UniProtKB:O00329	RO:0002436	drug_central	Inhibition of PI3Kdelta (unknown origin)	biolink:Association
DrugCentral:463	biolink:molecularly_interacts_with	UniProtKB:Q9Y2T3	RO:0002436	drug_central	Inhibition of GDA by colorimetric assay	biolink:Association
DrugCentral:463	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human AChE using acetylthiocholine iodide as substrate treated 5 mins before substrate addition measured up to 4 mins by Ellman's method	biolink:Association
DrugCentral:463	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:463	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Competitive binding affinity to human adenosine A2A receptor expressed in HEK293 cells after 60 mins by fluorescence polarization assay in presence of MRS5346	biolink:Association
DrugCentral:464	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central	Mechanism of Action; CHEMBL1977; SINGLE PROTEIN	biolink:Association
DrugCentral:465	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central	Binding affinity to VDR receptor	biolink:Association
DrugCentral:466	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central		biolink:Association
DrugCentral:466	biolink:molecularly_interacts_with	UniProtKB:Q6VVX0	RO:0002436	drug_central		biolink:Association
DrugCentral:466	biolink:molecularly_interacts_with	UniProtKB:O15528	RO:0002436	drug_central		biolink:Association
DrugCentral:466	biolink:molecularly_interacts_with	UniProtKB:P02774	RO:0002436	drug_central	Binding affinity to human vitamin D binding protein	biolink:Association
DrugCentral:471	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (H-D-Phe-Pip-Arg-pNA) thrombin in vitro.	biolink:Association
DrugCentral:471	biolink:molecularly_interacts_with	UniProtKB:P07477	RO:0002436	drug_central	Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (Boc-Phe-Ser-Arg-AMC) for trypsin in vitro.	biolink:Association
DrugCentral:471	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:471	biolink:molecularly_interacts_with	UniProtKB:P06870	RO:0002436	drug_central	Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (H-D-Pro-Phe-Arg-pNA) for plasma kallikrein in vitro.	biolink:Association
DrugCentral:471	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:471	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:471	biolink:molecularly_interacts_with	UniProtKB:Q04756	RO:0002436	drug_central		biolink:Association
DrugCentral:475	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central		biolink:Association
DrugCentral:475	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:475	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:475	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:475	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:475	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:475	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:475	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:475	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:475	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:478	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central	inhibitION the aldosterone-induced MR activity	biolink:Association
DrugCentral:480	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central		biolink:Association
DrugCentral:484	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central		biolink:Association
DrugCentral:484	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	Inhibitory activity against thrombin	biolink:Association
DrugCentral:484	biolink:molecularly_interacts_with	UniProtKB:P09960	RO:0002436	drug_central	Inhibitory activity against Leukotriene A4 hydrolase from human leukocytes	biolink:Association
DrugCentral:484	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate assessed as formation of prostanoid products preincubated for 10 mins prior to substrate addition measured after 2 mins by Ellman's method	biolink:Association
DrugCentral:484	biolink:molecularly_interacts_with	UniProtKB:P00797	RO:0002436	drug_central	Antihypertensive activity against human renin	biolink:Association
DrugCentral:484	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate assessed as formation of prostanoid products preincubated for 10 mins prior to substrate addition measured after 2 mins by Ellman's method	biolink:Association
DrugCentral:486	biolink:molecularly_interacts_with	UniProtKB:P42785	RO:0002436	drug_central	Inhibition of [3H]- (+) - pentazocine binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellum	biolink:Association
DrugCentral:486	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity against Sigma receptor type 1 was determined by the displacement of [3H]pentazocine radioligand	biolink:Association
DrugCentral:487	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:487	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Displacement of [3H]DHA from human beta2 adrenoceptor by liquid scintillation counter	biolink:Association
DrugCentral:488	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:488	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:488	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:488	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central	Binding affinity to alpha7 nAChR (unknown origin)	biolink:Association
DrugCentral:488	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	Binding affinity to alpha4beta2 nAChR (unknown origin)	biolink:Association
DrugCentral:488	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central	Binding affinity to alpha4beta2 nAChR (unknown origin)	biolink:Association
DrugCentral:488	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:488	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Affinity for inactive human SkM1 sodium channel expressed in HEK293 cells	biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Blockade of human Nav1.7 channel expressed in HEK293 cells by FRET assay	biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:489	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:492	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:492	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:493	biolink:molecularly_interacts_with	UniProtKB:P28845	RO:0002436	drug_central	Ability to convert [3H]cortisol to the tritium labeled cortisone in the presence of human 11 beta hydroxysteroid dehydrogenase type 2	biolink:Association
DrugCentral:494	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Binding affinity towards muscarinic m2 receptor	biolink:Association
DrugCentral:494	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Binding affinity towards muscarinic m1 receptor	biolink:Association
DrugCentral:494	biolink:molecularly_interacts_with	UniProtKB:P42785	RO:0002436	drug_central	Inhibition of [3H]- (+) - pentazocine binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellum	biolink:Association
DrugCentral:494	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity against Sigma receptor type 1 was determined by the displacement of [3H]pentazocine radioligand	biolink:Association
DrugCentral:495	biolink:molecularly_interacts_with	UniProtKB:P30559	RO:0002436	drug_central	oxytocin receptors expressed in COS-7 cells	biolink:Association
DrugCentral:495	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central	vasopressin V2 receptors expressed in COS-7 cells	biolink:Association
DrugCentral:495	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central		biolink:Association
DrugCentral:496	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:496	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:496	biolink:molecularly_interacts_with	UniProtKB:B2RXH2	RO:0002436	drug_central	Uncompetitive inhibition of JMJD2E relative to alpha-ketoglutarate	biolink:Association
DrugCentral:496	biolink:molecularly_interacts_with	UniProtKB:P20711	RO:0002436	drug_central	Mechanism of Action; CHEMBL1843; SINGLE PROTEIN	biolink:Association
DrugCentral:497	biolink:molecularly_interacts_with	UniProtKB:P22079	RO:0002436	drug_central	Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC	biolink:Association
DrugCentral:497	biolink:molecularly_interacts_with	UniProtKB:P07202	RO:0002436	drug_central		biolink:Association
DrugCentral:499	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action; CHEMBL231; SINGLE PROTEIN	biolink:Association
DrugCentral:502	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central	Mechanism of Action; CHEMBL1987; SINGLE PROTEIN	biolink:Association
DrugCentral:505	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:505	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:510	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central		biolink:Association
DrugCentral:511	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:511	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:512	biolink:molecularly_interacts_with	UniProtKB:P00390	RO:0002436	drug_central	Inhibition of human recombinant glutathione reductase using glutathione as substrate preincubated for 30 mins by colorimetric assay	biolink:Association
DrugCentral:513	biolink:molecularly_interacts_with	UniProtKB:P50416	RO:0002436	drug_central		biolink:Association
DrugCentral:516	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:516	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Mechanism of Action; CHEMBL224; SINGLE PROTEIN	biolink:Association
DrugCentral:517	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:517	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:518	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibitory activity against cell-free canine COX-1	biolink:Association
DrugCentral:518	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition of human recombinant COX2 after 5 mins	biolink:Association
DrugCentral:520	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:520	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against IKr potassium channel	biolink:Association
DrugCentral:522	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:526	biolink:molecularly_interacts_with	UniProtKB:P46059	RO:0002436	drug_central		biolink:Association
DrugCentral:527	biolink:molecularly_interacts_with	UniProtKB:P46059	RO:0002436	drug_central		biolink:Association
DrugCentral:537	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:542	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central		biolink:Association
DrugCentral:542	biolink:molecularly_interacts_with	UniProtKB:P31391	RO:0002436	drug_central		biolink:Association
DrugCentral:542	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:547	biolink:molecularly_interacts_with	UniProtKB:P03956	RO:0002436	drug_central		biolink:Association
DrugCentral:547	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central		biolink:Association
DrugCentral:547	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central		biolink:Association
DrugCentral:547	biolink:molecularly_interacts_with	UniProtKB:P21964	RO:0002436	drug_central		biolink:Association
DrugCentral:547	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:548	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central		biolink:Association
DrugCentral:548	biolink:molecularly_interacts_with	UniProtKB:P32241	RO:0002436	drug_central		biolink:Association
DrugCentral:558	biolink:molecularly_interacts_with	UniProtKB:P25098	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Dose Response of inhibitors of GRK2 binding with RNA aptamer, Cherry Pick 1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488855]	biolink:Association
DrugCentral:558	biolink:molecularly_interacts_with	UniProtKB:P29350	RO:0002436	drug_central		biolink:Association
DrugCentral:558	biolink:molecularly_interacts_with	UniProtKB:Q06124	RO:0002436	drug_central		biolink:Association
DrugCentral:564	biolink:molecularly_interacts_with	UniProtKB:P14920	RO:0002436	drug_central		biolink:Association
DrugCentral:565	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:565	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central		biolink:Association
DrugCentral:565	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central		biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP)	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibitory activity against cloned human CA12	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase IV (hCAIV)	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 13 after 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX-1 in U-937 (human lymphoma) cell microsomes.	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human recombinant full length CA3 pre-incubated for 15 mins by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:O15530	RO:0002436	drug_central	Inhibition of recombinant PDK1 using RPRAATF as substrate by scintillation counting	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 5a after 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 14 after 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 7 after 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase IX at 0.09 uM	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase I (hCAI)	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 5b after 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human full length recombinant carbonic anhydrase 6 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:568	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	Inhibitory concentration against p38 alpha MAP kinase calculated by CoMFA model; FlexX score=-12.4 kcal/mol	biolink:Association
DrugCentral:569	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:569	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:571	biolink:molecularly_interacts_with	UniProtKB:Q16348	RO:0002436	drug_central		biolink:Association
DrugCentral:574	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central		biolink:Association
DrugCentral:574	biolink:molecularly_interacts_with	UniProtKB:P31391	RO:0002436	drug_central		biolink:Association
DrugCentral:574	biolink:molecularly_interacts_with	UniProtKB:P35236	RO:0002436	drug_central		biolink:Association
DrugCentral:574	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P03956	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P20815	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P31391	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:575	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central		biolink:Association
DrugCentral:576	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central		biolink:Association
DrugCentral:576	biolink:molecularly_interacts_with	UniProtKB:P31391	RO:0002436	drug_central		biolink:Association
DrugCentral:577	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central		biolink:Association
DrugCentral:577	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:578	biolink:molecularly_interacts_with	UniProtKB:P49327	RO:0002436	drug_central	Inhibition of human FAS assessed as synthesis of long chain fatty acids from malonyl CoA after 60 mins by fluorescence assay	biolink:Association
DrugCentral:578	biolink:molecularly_interacts_with	UniProtKB:P00488	RO:0002436	drug_central		biolink:Association
DrugCentral:579	biolink:molecularly_interacts_with	UniProtKB:P32238	RO:0002436	drug_central		biolink:Association
DrugCentral:581	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:581	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding affinity to human recombinant Tie2 by SPR assay	biolink:Association
DrugCentral:581	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human Potassium channel HERG expressed in mammalian cells	biolink:Association
DrugCentral:583	biolink:molecularly_interacts_with	UniProtKB:P22888	RO:0002436	drug_central		biolink:Association
DrugCentral:583	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central	GRAC: human GnRH1 selective antagonist	biolink:Association
DrugCentral:584	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:584	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:584	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:584	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:584	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:588	biolink:molecularly_interacts_with	UniProtKB:P07339	RO:0002436	drug_central		biolink:Association
DrugCentral:588	biolink:molecularly_interacts_with	UniProtKB:P14091	RO:0002436	drug_central		biolink:Association
DrugCentral:588	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:588	biolink:molecularly_interacts_with	UniProtKB:Q13443	RO:0002436	drug_central		biolink:Association
DrugCentral:589	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:593	biolink:molecularly_interacts_with	UniProtKB:P10415	RO:0002436	drug_central	Binding affinity to Bcl-2 by NMR titration assay	biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P32238	RO:0002436	drug_central	Binding affinity towards cholecystokinin receptor by displacement of [125I]CCK-33 from guinea pig brain tissue	biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P32239	RO:0002436	drug_central	Binding affinity towards cholecystokinin receptor by displacement of [125I]CCK-33 from guinea pig brain tissue	biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P34981	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Inhibition of [3H]Ro-151788 binding to human GABA A receptor (alpha-1-beta-3-gamma-2) stably expressed in L(tk-) cells.	biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Inhibition of [3H]Ro-151788 binding to human GABA A receptor (alpha-1-beta-3-gamma-2) stably expressed in L(tk-) cells.	biolink:Association
DrugCentral:594	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Inhibition of [3H]Ro-151788 binding to human GABA A receptor (alpha-1-beta-3-gamma-2) stably expressed in L(tk-) cells.	biolink:Association
DrugCentral:597	biolink:molecularly_interacts_with	UniProtKB:O75751	RO:0002436	drug_central	Inhibition of human OCT3-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:597	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of human OCT1-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:597	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:597	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	Inhibition of human neutrophils gelatinase B after 30 mins by fluorescence plate reader	biolink:Association
DrugCentral:597	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:597	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:597	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central	Inhibition of human rheumatoid synovial fibroblasts gelatinase A after 30 mins by fluorescence plate reader	biolink:Association
DrugCentral:600	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:600	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:602	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:602	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:602	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:605	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central		biolink:Association
DrugCentral:606	biolink:molecularly_interacts_with	UniProtKB:Q05397	RO:0002436	drug_central	Binding affinity to biotinylated human FAK FAT domain by biolayer interoferometry	biolink:Association
DrugCentral:607	biolink:molecularly_interacts_with	UniProtKB:P04156	RO:0002436	drug_central	Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cells	biolink:Association
DrugCentral:607	biolink:molecularly_interacts_with	UniProtKB:P16083	RO:0002436	drug_central	Inhibition of human recombinant NQO2	biolink:Association
DrugCentral:607	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:609	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central		biolink:Association
DrugCentral:609	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:610	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:610	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Mechanism of Action; CHEMBL242; SINGLE PROTEIN	biolink:Association
DrugCentral:611	biolink:molecularly_interacts_with	UniProtKB:P18054	RO:0002436	drug_central	Inhibition of human platelet-type N-terminally His6-tagged 12-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by UV-vis spectrophotometer analysis	biolink:Association
DrugCentral:611	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central	Inhibition of human 5-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by UV-vis spectrophotometer analysis	biolink:Association
DrugCentral:611	biolink:molecularly_interacts_with	UniProtKB:O15296	RO:0002436	drug_central	Inhibition of human reticulocyte N-terminally His6-tagged 15-lipoxygenase-2 assessed as conjugated diene product formation using arachidonic acid by UV-vis spectrophotometer analysis	biolink:Association
DrugCentral:611	biolink:molecularly_interacts_with	UniProtKB:P16050	RO:0002436	drug_central	Inhibition of human reticulocyte N-terminally His6-tagged 15-lipoxygenase-1 assessed as conjugated diene product formation using arachidonic acid by UV-vis spectrophotometer analysis	biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against IKr potassium channel	biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:Q96JM7	RO:0002436	drug_central	Inhibition of L3MBTL3 by alpha-screening	biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:Q9Y468	RO:0002436	drug_central	Inhibition of L3MBTL1 by alpha-screening	biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:Q05BQ5	RO:0002436	drug_central	Inhibition of MBTD1 by alpha-screening	biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:616	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:618	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:618	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:619	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:619	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:619	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P41968	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity model	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Compound was evaluated for the binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cells	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P04156	RO:0002436	drug_central	Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cells	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Binding affinity to SERT (unknown origin) by radioligand binding assay	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P0DP23	RO:0002436	drug_central	Binding affinity to human calmodulin expressed in Escherichia coli using M124C-mBBr fluorescent biosensor by spectrofluorometer analysis	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P0DP24	RO:0002436	drug_central	Binding affinity to human calmodulin expressed in Escherichia coli using M124C-mBBr fluorescent biosensor by spectrofluorometer analysis	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P0DP25	RO:0002436	drug_central	Binding affinity to human calmodulin expressed in Escherichia coli using M124C-mBBr fluorescent biosensor by spectrofluorometer analysis	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central	Inhibition of [3H]1 binding to dextromethorpin binding site of guinea pig microsomal pellet P3 N-methyl-D-aspartate glutamate receptor	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:O60391	RO:0002436	drug_central	Inhibition of [3H]1 binding to dextromethorpin binding site of guinea pig microsomal pellet P3 N-methyl-D-aspartate glutamate receptor	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Inhibition of [3H]1 binding to dextromethorpin binding site of guinea pig microsomal pellet P3 N-methyl-D-aspartate glutamate receptor	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	Inhibition of [3H]1 binding to dextromethorpin binding site of guinea pig microsomal pellet P3 N-methyl-D-aspartate glutamate receptor	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	Inhibition of [3H]1 binding to dextromethorpin binding site of guinea pig microsomal pellet P3 N-methyl-D-aspartate glutamate receptor	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central	Inhibition of [3H]1 binding to dextromethorpin binding site of guinea pig microsomal pellet P3 N-methyl-D-aspartate glutamate receptor	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central	Inhibition of [3H]1 binding to dextromethorpin binding site of guinea pig microsomal pellet P3 N-methyl-D-aspartate glutamate receptor	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in CHO cells by liquid scintillation counting	biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P21817	RO:0002436	drug_central		biolink:Association
DrugCentral:621	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:622	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:622	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 6 receptor	biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cells	biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK cells	biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO cells	biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells	biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central	Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in HEK cells	biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:623	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:624	biolink:molecularly_interacts_with	UniProtKB:P04156	RO:0002436	drug_central		biolink:Association
DrugCentral:624	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of PAD4 (unknown origin)	biolink:Association
DrugCentral:624	biolink:molecularly_interacts_with	UniProtKB:Q9UM07	RO:0002436	drug_central	Inhibition of PAD4 by ABPP-based assay	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human recombinant full length CA4 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human recombinant full length CA3 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant full length CA5A by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant full length CA14 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant full length CA7 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human recombinant full length CA1 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant full length CA5B by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human recombinant full length CA6 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:625	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central	Mechanism of Action; CHEMBL1876; SINGLE PROTEIN	biolink:Association
DrugCentral:626	biolink:molecularly_interacts_with	UniProtKB:Q12791	RO:0002436	drug_central	Chlorzoxazone-stimulated activity of BK(Ca) channels in neuroblastoma IMR-32 cells	biolink:Association
DrugCentral:626	biolink:molecularly_interacts_with	UniProtKB:O15554	RO:0002436	drug_central		biolink:Association
DrugCentral:626	biolink:molecularly_interacts_with	UniProtKB:P35228	RO:0002436	drug_central	Inhibitory activity against Inducible nitric oxide synthase	biolink:Association
DrugCentral:626	biolink:molecularly_interacts_with	UniProtKB:P29475	RO:0002436	drug_central	Inhibitory activity against Neuronal nitric oxide synthase	biolink:Association
DrugCentral:626	biolink:molecularly_interacts_with	UniProtKB:P29474	RO:0002436	drug_central	Inhibitory activity against Endothelial nitric oxide synthase	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysis	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX1	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition of COX2	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5b after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5a after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 6 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 13 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:629	biolink:molecularly_interacts_with	UniProtKB:P56817	RO:0002436	drug_central	Inhibition of human Beta-secretase 1	biolink:Association
DrugCentral:630	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against IKr potassium channel	biolink:Association
DrugCentral:630	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:630	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:631	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central		biolink:Association
DrugCentral:631	biolink:molecularly_interacts_with	UniProtKB:P43119	RO:0002436	drug_central		biolink:Association
DrugCentral:631	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:631	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:631	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central		biolink:Association
DrugCentral:631	biolink:molecularly_interacts_with	UniProtKB:Q13258	RO:0002436	drug_central		biolink:Association
DrugCentral:633	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:637	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:637	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:640	biolink:molecularly_interacts_with	UniProtKB:P16444	RO:0002436	drug_central		biolink:Association
DrugCentral:641	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central		biolink:Association
DrugCentral:642	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:642	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:644	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central		biolink:Association
DrugCentral:644	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:644	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central		biolink:Association
DrugCentral:645	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:645	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:645	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:645	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central		biolink:Association
DrugCentral:647	biolink:molecularly_interacts_with	UniProtKB:P41180	RO:0002436	drug_central	Positive allosteric modulation of calcium sensing receptor by cell based assay	biolink:Association
DrugCentral:647	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:648	biolink:molecularly_interacts_with	UniProtKB:Q9Y271	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:654	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:657	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:658	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Transactivation of GAL4-fused PPARalpha LBD expressed in HepG2 cells after 20 hrs by luminescence assay	biolink:Association
DrugCentral:659	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central	Inhibitory activity against HeLa cell Topoisomerase II	biolink:Association
DrugCentral:659	biolink:molecularly_interacts_with	UniProtKB:Q02880	RO:0002436	drug_central	Inhibitory activity against HeLa cell Topoisomerase II	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central	DRUGMATRIX: HMG-CoA Reductase enzyme inhibition (substrate: [14C]HMG-CoA)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity to dopamine receptor D2	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Binding affinity to dopamine receptor D1	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:Q13639	RO:0002436	drug_central	Binding affinity towards Serotonin 5-hydroxytryptamine 4 receptor	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG in MCF7 cells	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:A5X5Y0	RO:0002436	drug_central	Compound was tested for 5-hydroxytryptamine 3 receptor binding affinity	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:O95264	RO:0002436	drug_central	Compound was tested for 5-hydroxytryptamine 3 receptor binding affinity	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Compound was tested for 5-hydroxytryptamine 3 receptor binding affinity	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:Q70Z44	RO:0002436	drug_central	Compound was tested for 5-hydroxytryptamine 3 receptor binding affinity	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:Q8WXA8	RO:0002436	drug_central	Compound was tested for 5-hydroxytryptamine 3 receptor binding affinity	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:660	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:661	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:661	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:661	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	In vitro binding affinity against human norepinephrine transporter in human embryonic kidney cell line by using [3H]-nisoxatine radioligand	biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]RTI-55 radioligand	biolink:Association
DrugCentral:663	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:667	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP)	biolink:Association
DrugCentral:667	biolink:molecularly_interacts_with	UniProtKB:P27707	RO:0002436	drug_central		biolink:Association
DrugCentral:668	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:670	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Displacement of [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human recombinant dopamine receptor D2S expressed in CHO cells at 0.5 nM concentration	biolink:Association
DrugCentral:670	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of AChE	biolink:Association
DrugCentral:670	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Ability to displace [3H]spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells	biolink:Association
DrugCentral:670	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	In vitro binding affinity on D3 receptor is inhibition of binding of [125I]- NCQ 298 to Sf9 cells infected with recombinant baculovirus	biolink:Association
DrugCentral:670	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:671	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:672	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:673	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:673	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:673	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nM	biolink:Association
DrugCentral:674	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central		biolink:Association
DrugCentral:674	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:676	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:676	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Mechanism of Action; CHEMBL216; SINGLE PROTEIN	biolink:Association
DrugCentral:682	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:682	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:682	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:690	biolink:molecularly_interacts_with	UniProtKB:P18031	RO:0002436	drug_central		biolink:Association
DrugCentral:690	biolink:molecularly_interacts_with	UniProtKB:P12236	RO:0002436	drug_central		biolink:Association
DrugCentral:690	biolink:molecularly_interacts_with	UniProtKB:P12235	RO:0002436	drug_central		biolink:Association
DrugCentral:690	biolink:molecularly_interacts_with	UniProtKB:P05141	RO:0002436	drug_central		biolink:Association
DrugCentral:691	biolink:molecularly_interacts_with	UniProtKB:P09884	RO:0002436	drug_central		biolink:Association
DrugCentral:691	biolink:molecularly_interacts_with	UniProtKB:Q9BZX2	RO:0002436	drug_central		biolink:Association
DrugCentral:691	biolink:molecularly_interacts_with	UniProtKB:Q9HA47	RO:0002436	drug_central		biolink:Association
DrugCentral:691	biolink:molecularly_interacts_with	UniProtKB:P60891	RO:0002436	drug_central		biolink:Association
DrugCentral:691	biolink:molecularly_interacts_with	UniProtKB:P31350	RO:0002436	drug_central	Inhibition of growth of K562 cells	biolink:Association
DrugCentral:691	biolink:molecularly_interacts_with	UniProtKB:P23921	RO:0002436	drug_central	Inhibition of K562 cell growth	biolink:Association
DrugCentral:694	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central		biolink:Association
DrugCentral:695	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Effective concentration against human PPARalpha expressed in HepG2 cells	biolink:Association
DrugCentral:695	biolink:molecularly_interacts_with	UniProtKB:P06858	RO:0002436	drug_central		biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation counting	biolink:Association
DrugCentral:700	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central	Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation counting	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Displacement of [3H]Win35428 from human recombinant DAT over-expressed in CHOK1 cells	biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P09211	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:701	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:703	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:704	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:704	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:704	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Displacement of [3H]RX821001 from human alpha2B adrenoceptor expressed in CHO cells after 60 mins by gamma counter	biolink:Association
DrugCentral:704	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:704	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:704	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central	Displacement of [3H]-clonidine from bovine imidazoline receptor I-1	biolink:Association
DrugCentral:704	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HeLa cells after 30 mins	biolink:Association
DrugCentral:704	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamster ovary (CHO) cells	biolink:Association
DrugCentral:704	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:704	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:708	biolink:molecularly_interacts_with	UniProtKB:Q9H244	RO:0002436	drug_central		biolink:Association
DrugCentral:708	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:708	biolink:molecularly_interacts_with	UniProtKB:P20813	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:711	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:714	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:714	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:717	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA))	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P25105	RO:0002436	drug_central	DRUGMATRIX: Platelet Activating Factor (PAF) radioligand binding (ligand: [3H] PAF)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P05093	RO:0002436	drug_central		biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:O15554	RO:0002436	drug_central	Inhibition of human cloned IK1 expressed in african green monkey COS7 cells by whole cell patch clamp assay	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assay	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of human placental microsome CYP19	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central	Inhibition of vasopressin-stimulated vasopressin V2 receptor in human HTLA cells pre-incubated for 20 mins measured on day 4 by beta arrestin-recruitment mediated luciferase reporter gene assay	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P40925	RO:0002436	drug_central	Inhibition of malate dehydrogenase (MDH)	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P51679	RO:0002436	drug_central	Inverse agonist activity at CCR4 in human HTLA cells assessed as depression of basal activity incubated for 20 mins by beta arrestin-recruitment mediated luciferase reporter gene assay in absence of CCL22	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P25024	RO:0002436	drug_central	Inhibition of CX3CL1-stimulated CX3CR1 in human HTLA cells pre-incubated for 20 mins measured on day 4 by beta arrestin-recruitment mediated luciferase reporter gene assay	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:P22001	RO:0002436	drug_central	Inhibition of cloned Kv1.3 channel expressed in mammalian cells by whole cell patch clamp assay	biolink:Association
DrugCentral:719	biolink:molecularly_interacts_with	UniProtKB:Q9Y271	RO:0002436	drug_central	DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4)	biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P22310	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity to 5-HT1A receptor (unknown origin)	biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 5A receptor was evaluated using [3H]-5-CT as radioligand	biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Binding affinity to human SERT	biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:722	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity against Sigma receptor type 1 was determined by the displacement of [3H]pentazocine radioligand	biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:Q16568	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:P30531	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:Q9UI33	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:O95264	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:723	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:725	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Displacement of [3H]diprenorphine from recombinant kappa opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:725	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Displacement of [3H]diprenorphine from recombinant delta opioid receptor expressed in C6 cells	biolink:Association
DrugCentral:725	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Displacement of [3H]diprenorphine from recombinant mu opioid receptor expressed in C6 cells	biolink:Association
DrugCentral:726	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:726	biolink:molecularly_interacts_with	UniProtKB:P23416	RO:0002436	drug_central		biolink:Association
DrugCentral:726	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central		biolink:Association
DrugCentral:726	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:726	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:726	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:726	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central		biolink:Association
DrugCentral:729	biolink:molecularly_interacts_with	UniProtKB:Q08828	RO:0002436	drug_central	Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1	biolink:Association
DrugCentral:729	biolink:molecularly_interacts_with	UniProtKB:P11166	RO:0002436	drug_central	Inhibition of [125I]7-IHPP-Fsk binding to glucose transporter of human erythrocyte membrane	biolink:Association
DrugCentral:729	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:729	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:729	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:732	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central	Displacement [3H]Arg human recombinant Vasopressin V2 receptor	biolink:Association
DrugCentral:732	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central	Displacement [3H]Arg human recombinant Vasopressin V1a receptor	biolink:Association
DrugCentral:734	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:734	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:734	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:734	biolink:molecularly_interacts_with	UniProtKB:Q09470	RO:0002436	drug_central	Activation of KV1.1 expressed in Xenopus laevis oocytes coexpressing Kvbeta1 W155A mutant assessed as increase in steady state current normalized to initial inactivating current by electrophysiology method	biolink:Association
DrugCentral:734	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:734	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:736	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:737	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of full length human CA2 cytosolic isoform by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:738	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:741	biolink:molecularly_interacts_with	UniProtKB:P25815	RO:0002436	drug_central	cromolyn blocked the coimmunoprecipitation of S100P and RAGE	biolink:Association
DrugCentral:741	biolink:molecularly_interacts_with	UniProtKB:Q9HC97	RO:0002436	drug_central	Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysis	biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:746	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:749	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:751	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central		biolink:Association
DrugCentral:754	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central	Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assay	biolink:Association
DrugCentral:757	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Mechanism of Action; CHEMBL245; SINGLE PROTEIN	biolink:Association
DrugCentral:758	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:759	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central		biolink:Association
DrugCentral:759	biolink:molecularly_interacts_with	UniProtKB:O60391	RO:0002436	drug_central		biolink:Association
DrugCentral:759	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:759	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central		biolink:Association
DrugCentral:759	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central		biolink:Association
DrugCentral:759	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central		biolink:Association
DrugCentral:759	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central		biolink:Association
DrugCentral:759	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:P62937	RO:0002436	drug_central		biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:Q02127	RO:0002436	drug_central		biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:P62942	RO:0002436	drug_central		biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:Q14973	RO:0002436	drug_central		biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:Q9NPD5	RO:0002436	drug_central		biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:P21462	RO:0002436	drug_central		biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central	Inhibition of human MRP2 expressed in dog MDCK2 cells	biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central	Inhibition of MRP1 in human 2008 cells assessed as Calcein AM accumulation treated 30 mins before Calcein AM addition measured up to 90 mins by fluorescence assay	biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:Q08209	RO:0002436	drug_central	Binding affinity to protein phosphatase, calcineurin (CN) was determined	biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:Q08752	RO:0002436	drug_central	Inhibition of fluorescein labeled cyclosporin binding to Cyp40 by fluorescence polarization competition assay	biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:P23284	RO:0002436	drug_central	Binding affinity to human Cyclophilin B	biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:P68106	RO:0002436	drug_central	The compound was tested for inhibition of Peptidyl-propyl isomerase (PPIase).	biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:Q02790	RO:0002436	drug_central	50% inhibitory concentration of competitive binding against hCyp-18 PPIase activity using uncoupled assay	biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central	Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells by Hoechst 33342 assay	biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:760	biolink:molecularly_interacts_with	UniProtKB:Q9Y6L6	RO:0002436	drug_central		biolink:Association
DrugCentral:761	biolink:molecularly_interacts_with	UniProtKB:P42262	RO:0002436	drug_central	Activity at human recombinant GluA2 receptor flip isoform expressed in HEK293 cells assessed as effect on glutamate-induced calcium flux by Fluo-4/AM staining-based fluorescence assay	biolink:Association
DrugCentral:761	biolink:molecularly_interacts_with	UniProtKB:P42261	RO:0002436	drug_central	Activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes co-expressing gamma2-TARP assessed as effect on 10 uM glutamate-induced current by voltage-clamp electrophysiological assay	biolink:Association
DrugCentral:761	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central	Mechanism of Action; CHEMBL1876; SINGLE PROTEIN	biolink:Association
DrugCentral:761	biolink:molecularly_interacts_with	UniProtKB:P42263	RO:0002436	drug_central		biolink:Association
DrugCentral:761	biolink:molecularly_interacts_with	UniProtKB:P48058	RO:0002436	drug_central		biolink:Association
DrugCentral:763	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Binding affinity towards Norepinephrine transporter using [3H]nisoxitine as radioligand	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Binding affinity towards Serotonin transporter using [3H]paroxetine as radioligand	biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P0DP23	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P0DP24	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P0DP25	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:765	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:766	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:766	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:766	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:766	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:769	biolink:molecularly_interacts_with	UniProtKB:Q9UPY5	RO:0002436	drug_central	Competitive inhibition of [3H]L-glutamate uptake at amino acid transport system xc- in human SNB19 cells by liquid scintillation counting	biolink:Association
DrugCentral:770	biolink:molecularly_interacts_with	UniProtKB:P09884	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363042; PROTEIN FAMILY	biolink:Association
DrugCentral:770	biolink:molecularly_interacts_with	UniProtKB:P28340	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363042; PROTEIN FAMILY	biolink:Association
DrugCentral:770	biolink:molecularly_interacts_with	UniProtKB:Q07864	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363042; PROTEIN FAMILY	biolink:Association
DrugCentral:770	biolink:molecularly_interacts_with	UniProtKB:P15309	RO:0002436	drug_central		biolink:Association
DrugCentral:770	biolink:molecularly_interacts_with	UniProtKB:P06746	RO:0002436	drug_central		biolink:Association
DrugCentral:773	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:773	biolink:molecularly_interacts_with	UniProtKB:Q14181	RO:0002436	drug_central		biolink:Association
DrugCentral:774	biolink:molecularly_interacts_with	UniProtKB:P62993	RO:0002436	drug_central	Inhibition of GST-Grb2 Tyrosine kinase SH2 domain binding to [3H]labeled-phosphopeptide (Ac-SpYVNK-NH-C(O)-CH2CH2H3)	biolink:Association
DrugCentral:774	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central		biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	Binding affinity to human thrombin	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:P07477	RO:0002436	drug_central	Inhibitory constant (Ki) was determined against human trypsin	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:P07478	RO:0002436	drug_central	Inhibitory constant (Ki) was determined against human trypsin	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:P35030	RO:0002436	drug_central	Inhibitory constant (Ki) was determined against human trypsin	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central	Inhibitory constant (Ki) was determined against human plasmin	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:P00742	RO:0002436	drug_central	Inhibitory constant (Ki) was determined against human Coagulation factor Xa (fXa)	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:P16083	RO:0002436	drug_central	Displacement of (S)-N4-(4-(3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanamido)butyl)-N1-(15-oxo-19-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10-trioxa-14-azanonadecyl)-2-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamido)succinamide from human recombinant NQO2 after 1 hr by densitometric analysis	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:P04070	RO:0002436	drug_central	Inhibitory constant (Ki) was determined against human Activated protein C	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:P00750	RO:0002436	drug_central	Inhibitory constant (Ki) was determined against human Tissue plasminogen activator (tissue plasminogen activator)	biolink:Association
DrugCentral:776	biolink:molecularly_interacts_with	UniProtKB:P05981	RO:0002436	drug_central		biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P08842	RO:0002436	drug_central		biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:779	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:780	biolink:molecularly_interacts_with	UniProtKB:P21817	RO:0002436	drug_central		biolink:Association
DrugCentral:780	biolink:molecularly_interacts_with	UniProtKB:Q15413	RO:0002436	drug_central	Mechanism of Action; CHEMBL2062; SINGLE PROTEIN	biolink:Association
DrugCentral:781	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:781	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:781	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:781	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:781	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:781	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:781	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:781	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:782	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Antagonist activity at recombinant human 5-HT6 receptor expressed in HEK293 cells assessed as 5-HT-induced intracellular cAMP production after 30 mins	biolink:Association
DrugCentral:782	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:782	biolink:molecularly_interacts_with	UniProtKB:P11413	RO:0002436	drug_central		biolink:Association
DrugCentral:784	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	GRAC: human M2 antagonist	biolink:Association
DrugCentral:784	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	GRAC: human M1 antagonist	biolink:Association
DrugCentral:784	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	GRAC: human M3 probe	biolink:Association
DrugCentral:784	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	GRAC: human M4 antagonist	biolink:Association
DrugCentral:784	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	Binding affinity (Ki) against binding of [3H]NMS using membranes from CHO cells expressing cloned human Muscarinic acetylcholine receptor M5	biolink:Association
DrugCentral:784	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:784	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:784	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central		biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P11274	RO:0002436	drug_central		biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central	Binding constant for full-length MEK1	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(K663Q) kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(G719S) kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central	Binding constant for FLT1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P42345	RO:0002436	drug_central	Inhibition of recombinant mTOR by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Binding constant for VEGFR2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Binding constant for FGFR3 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q8TDR2	RO:0002436	drug_central	Binding constant for STK35 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Binding constant for PDGFRA kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P49674	RO:0002436	drug_central	Binding constant for full-length CSNK1E	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Binding constant for RIPK2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q01538	RO:0002436	drug_central	Binding affinity to human full-length His-tagged Myt1 kinase expressed in HEK293 cells by TR-FRET based binding assay	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central	Binding constant for EPHB4 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(Kin.Dom.2/JH1 - catalytic) kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q52WX2	RO:0002436	drug_central	Binding constant for SBK1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Binding constant for AURKA kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9NYL2	RO:0002436	drug_central	Binding constant for ZAK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O15264	RO:0002436	drug_central	Inhibition of p38 kinase	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P53778	RO:0002436	drug_central	Inhibition of p38 kinase	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q15759	RO:0002436	drug_central	Inhibition of p38 kinase	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	Inhibition of p38 kinase	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P43405	RO:0002436	drug_central	Binding constant for SYK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P30291	RO:0002436	drug_central	Binding constant for WEE1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P04049	RO:0002436	drug_central	Binding constant for RAF1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central	Binding constant for full-length BTK	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O43283	RO:0002436	drug_central	Binding constant for LZK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P21709	RO:0002436	drug_central	Binding constant for EPHA1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for MAP4K1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q8NG66	RO:0002436	drug_central	Binding constant for NEK11 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P15056	RO:0002436	drug_central	Binding constant for BRAF kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q5VT25	RO:0002436	drug_central	Binding constant for MRCKA kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O43318	RO:0002436	drug_central	Binding constant for TAK1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P29322	RO:0002436	drug_central	Binding constant for EPHA8 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P29317	RO:0002436	drug_central	Binding constant for EPHA2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Binding constant for EPHA3 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central	Binding constant for full-length CSK	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q59H18	RO:0002436	drug_central	Binding constant for full-length TNNI3K	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	Binding constant for ERBB2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	Binding constant for FGFR1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Binding constant for FGFR2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q8NI60	RO:0002436	drug_central	Binding constant for ADCK3 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O00506	RO:0002436	drug_central	Binding constant for YSK1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9Y6R4	RO:0002436	drug_central	Binding constant for MAP3K4 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding constant for MINK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9NRP7	RO:0002436	drug_central	Binding constant for STK36 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(L576P) kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central	Binding constant for ERBB4 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Binding constant for EPHA6 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q99640	RO:0002436	drug_central	Binding constant for PKMYT1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q96GD4	RO:0002436	drug_central	Inhibition of AurB	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O00238	RO:0002436	drug_central	Binding constant for BMPR1B kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Binding constant for TYK2(JH2domain-pseudokinase) kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q13043	RO:0002436	drug_central	Binding constant for MST1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q13882	RO:0002436	drug_central	Binding constant for PTK6 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9UL54	RO:0002436	drug_central	Binding constant for TAOK2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P51955	RO:0002436	drug_central	Binding constant for NEK2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P51813	RO:0002436	drug_central	Binding constant for full-length BMX	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P54756	RO:0002436	drug_central	Binding constant for EPHA5 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P53667	RO:0002436	drug_central	Binding constant for full-length LIMK1	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P54764	RO:0002436	drug_central	Binding constant for EPHA4 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central	Binding constant for EPHB1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P42336	RO:0002436	drug_central	Inhibition of recombinant PI3Kalpha by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central	Binding constant for TNK2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q15569	RO:0002436	drug_central	Binding constant for TESK1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q04771	RO:0002436	drug_central	Binding constant for ACVR1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q6DT37	RO:0002436	drug_central	Binding constant for DMPK2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9Y5S2	RO:0002436	drug_central	Binding constant for MRCKB kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding constant for MAP3K2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding constant for ULK3 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9P289	RO:0002436	drug_central	Binding constant for full-length MST4	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q13705	RO:0002436	drug_central	Binding constant for ACVR2B kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P21860	RO:0002436	drug_central	Binding constant for ERBB3 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O00329	RO:0002436	drug_central	Inhibition of recombinant PI3Kdelta by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for full-length SNF1LK2	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9H2K8	RO:0002436	drug_central	Binding constant for TAOK3 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9H3Y6	RO:0002436	drug_central	Binding constant for SRMS kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9Y2K2	RO:0002436	drug_central	Binding constant for QSK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central	Inhibition of MEK	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central	Inhibition of MEK	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P0C1S8	RO:0002436	drug_central	Binding constant for WEE2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central	Binding affinity to wild type DDR2 (unknown origin) by FLiK assay	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P37023	RO:0002436	drug_central	Binding constant for ACVRL1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P36896	RO:0002436	drug_central	Binding constant for ACVR1B kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P36894	RO:0002436	drug_central	Binding constant for BMPR1A kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P36897	RO:0002436	drug_central	Binding constant for TGFBR1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P37173	RO:0002436	drug_central	Binding constant for TGFBR2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9P2K8	RO:0002436	drug_central	Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(M918T) kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q09013	RO:0002436	drug_central	Binding constant for DMPK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:O95819	RO:0002436	drug_central	Binding constant for MAP4K4 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P27037	RO:0002436	drug_central	Binding constant for ACVR2A kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9H1R3	RO:0002436	drug_central	Binding constant for MYLK2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P29323	RO:0002436	drug_central	Binding constant for EPHB2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q15759	RO:0002436	drug_central	Binding constant for full-length p38-beta	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central	Binding constant for full-length MEK2	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q86Y07	RO:0002436	drug_central	Binding constant for VRK2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P53671	RO:0002436	drug_central	Binding constant for full-length LIMK2	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P54753	RO:0002436	drug_central	Binding constant for EPHB3 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P42680	RO:0002436	drug_central	Binding constant for TEC kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding constant for MAP3K3 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q9UBE8	RO:0002436	drug_central	Binding constant for full-length NLK	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P57059	RO:0002436	drug_central	Binding constant for SNF1LK kinase domain	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	Binding constant for full-length p38-alpha	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Inhibition of wild type Bcr-Abl	biolink:Association
DrugCentral:785	biolink:molecularly_interacts_with	UniProtKB:P11274	RO:0002436	drug_central	Inhibition of wild type Bcr-Abl	biolink:Association
DrugCentral:786	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central		biolink:Association
DrugCentral:786	biolink:molecularly_interacts_with	UniProtKB:O95255	RO:0002436	drug_central		biolink:Association
DrugCentral:786	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:786	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:786	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:786	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central	Inhibitory concentration against Clostridium histolyticum Collagenase	biolink:Association
DrugCentral:788	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central		biolink:Association
DrugCentral:788	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central		biolink:Association
DrugCentral:789	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:789	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of AChE	biolink:Association
DrugCentral:789	biolink:molecularly_interacts_with	UniProtKB:Q9Y5N1	RO:0002436	drug_central	Inhibition of histamine H3 receptor	biolink:Association
DrugCentral:789	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:789	biolink:molecularly_interacts_with	UniProtKB:P07510	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:789	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:789	biolink:molecularly_interacts_with	UniProtKB:Q04844	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:789	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:790	biolink:molecularly_interacts_with	UniProtKB:P26358	RO:0002436	drug_central		biolink:Association
DrugCentral:790	biolink:molecularly_interacts_with	UniProtKB:Q9Y6K1	RO:0002436	drug_central	Mechanism of Action; CHEMBL1992; SINGLE PROTEIN	biolink:Association
DrugCentral:792	biolink:molecularly_interacts_with	UniProtKB:Q16665	RO:0002436	drug_central	Activation of human HIF1alpha expressed in DFX-induced human U2OS cells incubated for 30 mins prior to DFX-induction measured after overnight incubation by luciferase reporter gene assay	biolink:Association
DrugCentral:795	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:795	biolink:molecularly_interacts_with	UniProtKB:P11413	RO:0002436	drug_central	Inhibition of human G6PDH using NADP as substrate by Lineweaver-Burke plot	biolink:Association
DrugCentral:795	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:798	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	ACE inhibition in human coronary artery tissue	biolink:Association
DrugCentral:799	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:799	biolink:molecularly_interacts_with	UniProtKB:P40925	RO:0002436	drug_central	Inhibition of malate dehydrogenase (MDH)	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:800	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	In vitro displacement of [3H]-diazepam from GABA-A Benzodiazepine receptor	biolink:Association
DrugCentral:801	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central		biolink:Association
DrugCentral:802	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Estrogen Receptor-beta Coactivator Binding Inhibitors ELISA Secondary Assay. (Class of assay: confirmatory) [Related pubchem assays: 633 (Primary screen preceding this ELISA dose response confirmation assay.), 733 (Primary dose response assay preceding this ELISA dose response confirmation assay.)]	biolink:Association
DrugCentral:806	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:806	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:809	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:809	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:809	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:810	biolink:molecularly_interacts_with	UniProtKB:Q05940	RO:0002436	drug_central	Mechanism of Action; CHEMBL1893; SINGLE PROTEIN	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363052; PROTEIN COMPLEX	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P48167	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363052; PROTEIN COMPLEX	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:P57789	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331041; SINGLE PROTEIN	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:Q7Z418	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331042; SINGLE PROTEIN	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:O14649	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321613; SINGLE PROTEIN	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:Q9NPC2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321614; SINGLE PROTEIN	biolink:Association
DrugCentral:811	biolink:molecularly_interacts_with	UniProtKB:O95069	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321615; SINGLE PROTEIN	biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	In vitro competitive binding versus [N-methyl-3H]WIN-35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)	biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:Q06432	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:812	biolink:molecularly_interacts_with	UniProtKB:Q7RTT9	RO:0002436	drug_central		biolink:Association
DrugCentral:813	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:813	biolink:molecularly_interacts_with	UniProtKB:P05026	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:813	biolink:molecularly_interacts_with	UniProtKB:P13637	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:813	biolink:molecularly_interacts_with	UniProtKB:P14415	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:813	biolink:molecularly_interacts_with	UniProtKB:P50993	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:813	biolink:molecularly_interacts_with	UniProtKB:P54709	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:813	biolink:molecularly_interacts_with	UniProtKB:P54710	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:813	biolink:molecularly_interacts_with	UniProtKB:Q13733	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095186; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:814	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:816	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:816	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:816	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:816	biolink:molecularly_interacts_with	UniProtKB:P28476	RO:0002436	drug_central		biolink:Association
DrugCentral:816	biolink:molecularly_interacts_with	UniProtKB:O75899	RO:0002436	drug_central		biolink:Association
DrugCentral:817	biolink:molecularly_interacts_with	UniProtKB:P30559	RO:0002436	drug_central		biolink:Association
DrugCentral:817	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central	Binding affinity against human vasopressin V2 receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors	biolink:Association
DrugCentral:817	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central	Binding affinity against human vasopressin V1a receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors	biolink:Association
DrugCentral:817	biolink:molecularly_interacts_with	UniProtKB:P47901	RO:0002436	drug_central	Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors	biolink:Association
DrugCentral:818	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:818	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:819	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:819	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:820	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:820	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:820	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:820	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:820	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:820	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:820	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:821	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central	Mechanism of Action; CHEMBL1994; SINGLE PROTEIN	biolink:Association
DrugCentral:822	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:824	biolink:molecularly_interacts_with	UniProtKB:P05112	RO:0002436	drug_central		biolink:Association
DrugCentral:824	biolink:molecularly_interacts_with	UniProtKB:P05113	RO:0002436	drug_central		biolink:Association
DrugCentral:824	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:824	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:824	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:824	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central	Displacement of [3H]-methyltrienolone from human progesterone receptor expressed in HEK293 cells	biolink:Association
DrugCentral:824	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Displacement of [3H]-methyltrienolone from human androgen receptor expressed in HEK293 cells	biolink:Association
DrugCentral:824	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:826	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:828	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:828	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:828	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:828	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:829	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:829	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:829	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:829	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:830	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:831	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:832	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:833	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Concentration required for 50% inhibition against Prostaglandin G/H synthase 1 from human	biolink:Association
DrugCentral:833	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Concentration required for 50% inhibition against Prostaglandin G/H synthase 2 from human	biolink:Association
DrugCentral:834	biolink:molecularly_interacts_with	UniProtKB:P32238	RO:0002436	drug_central		biolink:Association
DrugCentral:835	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:835	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:835	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	In vitro binding affinity against alpha-2D adrenergic receptor of male Wistar rat	biolink:Association
DrugCentral:835	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Agonist activity at human recombinant alpha2A adrenergic receptor expressed in CHO cells assessed as induction of [35S]GTPgammaS binding after 60 mins by scintillation counting	biolink:Association
DrugCentral:835	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:835	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:836	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation counting	biolink:Association
DrugCentral:836	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptor	biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptor	biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	GRAC: human a1A selective antagonist	biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptor	biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptor	biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptor	biolink:Association
DrugCentral:837	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Displacement of [125 I]AB-MECA from human Adenosine A3 receptor expressed in HEK cells	biolink:Association
DrugCentral:841	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:841	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of human recombinant MAOA by spectrophotometrically	biolink:Association
DrugCentral:841	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Inhibition of [3H]5-HT uptake at human SERT expressed in HEK293 cells preincubated for 10 mins prior to substrate addition measured after 4 mins by FLIPR assay	biolink:Association
DrugCentral:841	biolink:molecularly_interacts_with	UniProtKB:Q05940	RO:0002436	drug_central	Mechanism of Action; CHEMBL1893; SINGLE PROTEIN	biolink:Association
DrugCentral:841	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central		biolink:Association
DrugCentral:841	biolink:molecularly_interacts_with	UniProtKB:Q16568	RO:0002436	drug_central		biolink:Association
DrugCentral:841	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:841	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:841	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:841	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:842	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:842	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:842	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:842	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:842	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central	Measured <i>vs.</i> exogenously expressed zeta1/epsilon3 (<i>GRIN1/GRIN2C</i>) subunits, at pH 6.9	biolink:Association
DrugCentral:844	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:844	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:844	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:846	biolink:molecularly_interacts_with	UniProtKB:P10827	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111462; PROTEIN COMPLEX	biolink:Association
DrugCentral:846	biolink:molecularly_interacts_with	UniProtKB:P10828	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111462; PROTEIN COMPLEX	biolink:Association
DrugCentral:847	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:847	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Agonist activity at human cloned mu opioid receptor by [35S]GTPgammaS binding assay	biolink:Association
DrugCentral:849	biolink:molecularly_interacts_with	UniProtKB:P42574	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Absorbance-based biochemical high throughput dose response assay for activators of procaspase-3. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463141, AID463197, AID463210, AID488941, AID488954, AID493114, AID493115, AID504328, AID504330]	biolink:Association
DrugCentral:849	biolink:molecularly_interacts_with	UniProtKB:P55210	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463141, AID463197, AID463210, AID488941, AID488954, AID493114, AID493115, AID504328, AID504330]	biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:852	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Binding affinity to GABAA alpha-5-beta-2-gamma-2 receptor	biolink:Association
DrugCentral:854	biolink:molecularly_interacts_with	UniProtKB:P43490	RO:0002436	drug_central	Binding affinity to NAMPT (2 to 491) (unknown origin) by surface plasmon resonance analysis	biolink:Association
DrugCentral:854	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	Activation of human recombinant SUR1/Kir6.2 channel expressed in HEK293 cells assessed as increase in ionic current by whole cell patch clamp assay	biolink:Association
DrugCentral:854	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	Activation of human recombinant SUR1/Kir6.2 channel expressed in HEK293 cells assessed as increase in ionic current by whole cell patch clamp assay	biolink:Association
DrugCentral:859	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central		biolink:Association
DrugCentral:859	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:859	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:859	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:859	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:861	biolink:molecularly_interacts_with	UniProtKB:O75762	RO:0002436	drug_central	inhibition of calcium response evoked by the TRPA1 agonist AITC (10uM) in IMR90	biolink:Association
DrugCentral:862	biolink:molecularly_interacts_with	UniProtKB:Q15118	RO:0002436	drug_central		biolink:Association
DrugCentral:862	biolink:molecularly_interacts_with	UniProtKB:Q15119	RO:0002436	drug_central		biolink:Association
DrugCentral:862	biolink:molecularly_interacts_with	UniProtKB:Q15120	RO:0002436	drug_central		biolink:Association
DrugCentral:862	biolink:molecularly_interacts_with	UniProtKB:Q16654	RO:0002436	drug_central		biolink:Association
DrugCentral:863	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central	Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AI	biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central		biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central		biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central		biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central		biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central		biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human full length carbonic anhydrase 4 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant cytosolic carbonic anhydrase 13 preincubated for 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay	biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of full length human recombinant CA VI	biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central		biolink:Association
DrugCentral:864	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central		biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central	Inhibition of recombinant human AKR1C3	biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:Q9HAW8	RO:0002436	drug_central	Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A10	biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:P10145	RO:0002436	drug_central	Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay	biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:P19224	RO:0002436	drug_central	Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A6	biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:Q9HAW7	RO:0002436	drug_central	Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A7	biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:O60656	RO:0002436	drug_central	Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A9	biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:P25024	RO:0002436	drug_central	Inhibition of wild type CXCR1 transfected in mouse L1.2 cells assessed as inhibition of CXCL8-induced cell migration pretreated for 15 mins measured after 4 hrs	biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:P22309	RO:0002436	drug_central	Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A1	biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:Q9UHC3	RO:0002436	drug_central		biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:O60218	RO:0002436	drug_central		biolink:Association
DrugCentral:865	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:866	biolink:molecularly_interacts_with	UniProtKB:O00408	RO:0002436	drug_central		biolink:Association
DrugCentral:866	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:866	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:866	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:866	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:866	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:866	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:867	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:867	biolink:molecularly_interacts_with	UniProtKB:P15559	RO:0002436	drug_central		biolink:Association
DrugCentral:867	biolink:molecularly_interacts_with	UniProtKB:Q9HC97	RO:0002436	drug_central	Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysis	biolink:Association
DrugCentral:867	biolink:molecularly_interacts_with	UniProtKB:Q16549	RO:0002436	drug_central	Inhibition of recombinant type 8 subtilisin using Arg-Glu-(EDANS)- Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys-(DALBCYL)-Arg fluorogenic substrate preincubated for 1 hr measured after 1 hr at 1 min interval by fluorescence assay	biolink:Association
DrugCentral:867	biolink:molecularly_interacts_with	UniProtKB:Q9BQB6	RO:0002436	drug_central		biolink:Association
DrugCentral:867	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:868	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:870	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 639 (Primary screen preceding this dose response confirmation assay.)]	biolink:Association
DrugCentral:871	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:873	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central		biolink:Association
DrugCentral:873	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:874	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Mechanism of Action; CHEMBL238; SINGLE PROTEIN	biolink:Association
DrugCentral:874	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Mechanism of Action; CHEMBL222; SINGLE PROTEIN	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:O95718	RO:0002436	drug_central		biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P62508	RO:0002436	drug_central		biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central	DRUGMATRIX: Vasopressin V1A radioligand binding (ligand: [125I] PhenylacetylTyr(Me)PheGlnAsnArgProArgTyr)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Displacement of [3H]Estradiol from human recombinant estrogen receptor alpha expressed in Sf9 cells after 2 hrs	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	In vitro displacement of 0.5 nM [3H]17-beta-estradiol from human Estrogen receptor beta	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:Q14376	RO:0002436	drug_central	Inhibition of human GalE by HPAEC assay	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:Q9Y271	RO:0002436	drug_central	DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4)	biolink:Association
DrugCentral:875	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:878	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Mechanism of Action; CHEMBL233; SINGLE PROTEIN	biolink:Association
DrugCentral:880	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 esterase activity by non-competitive Lineweaver-Burke plot	biolink:Association
DrugCentral:880	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 esterase activity by noncompetitive Lineweaver-Burke plot	biolink:Association
DrugCentral:880	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:880	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:880	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central		biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central	Inhibition of [3H]- ouabain binding to digitalis receptor	biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:P05026	RO:0002436	drug_central	Inhibition of [3H]- ouabain binding to digitalis receptor	biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:P13637	RO:0002436	drug_central	Inhibition of [3H]- ouabain binding to digitalis receptor	biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:P14415	RO:0002436	drug_central	Inhibition of [3H]- ouabain binding to digitalis receptor	biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:P50993	RO:0002436	drug_central	Inhibition of [3H]- ouabain binding to digitalis receptor	biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:P54709	RO:0002436	drug_central	Inhibition of [3H]- ouabain binding to digitalis receptor	biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:P54710	RO:0002436	drug_central	Inhibition of [3H]- ouabain binding to digitalis receptor	biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:Q13733	RO:0002436	drug_central	Inhibition of [3H]- ouabain binding to digitalis receptor	biolink:Association
DrugCentral:881	biolink:molecularly_interacts_with	UniProtKB:P40763	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Dose response cell-based assay to measure STAT3 inhibition. (Class of assay: confirmatory) [Related pubchem assays: 920, 1317, 1265, 1308, 862 ]	biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:P51449	RO:0002436	drug_central	Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding domain	biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central	Inhibitory activity against Na+/K+ ATPase was determined	biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:P05026	RO:0002436	drug_central	Inhibitory activity against Na+/K+ ATPase was determined	biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:P13637	RO:0002436	drug_central	Inhibitory activity against Na+/K+ ATPase was determined	biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:P14415	RO:0002436	drug_central	Inhibitory activity against Na+/K+ ATPase was determined	biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:P50993	RO:0002436	drug_central	Inhibitory activity against Na+/K+ ATPase was determined	biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:P54709	RO:0002436	drug_central	Inhibitory activity against Na+/K+ ATPase was determined	biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:P54710	RO:0002436	drug_central	Inhibitory activity against Na+/K+ ATPase was determined	biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:Q13733	RO:0002436	drug_central	Inhibitory activity against Na+/K+ ATPase was determined	biolink:Association
DrugCentral:882	biolink:molecularly_interacts_with	UniProtKB:P40763	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Dose response cell-based assay to measure STAT3 inhibition. (Class of assay: confirmatory) [Related pubchem assays: 920, 1317, 1265, 1308, 862 ]	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:885	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:886	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Mechanism of Action; CHEMBL233; SINGLE PROTEIN	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:887	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:888	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:889	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:889	biolink:molecularly_interacts_with	UniProtKB:Q8IWT1	RO:0002436	drug_central		biolink:Association
DrugCentral:889	biolink:molecularly_interacts_with	UniProtKB:Q9NY72	RO:0002436	drug_central		biolink:Association
DrugCentral:889	biolink:molecularly_interacts_with	UniProtKB:O60939	RO:0002436	drug_central		biolink:Association
DrugCentral:889	biolink:molecularly_interacts_with	UniProtKB:Q07699	RO:0002436	drug_central		biolink:Association
DrugCentral:889	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:893	biolink:molecularly_interacts_with	UniProtKB:Q99808	RO:0002436	drug_central	GRAC: human ENT1 selective inhibitor	biolink:Association
DrugCentral:893	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:893	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:893	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:894	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:894	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:894	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:894	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:Q06432	RO:0002436	drug_central		biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of P-glycoprotein expressed in A2780/ADR cells by calcein AM assay	biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human Potassium channel HERG expressed in mammalian cells	biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:Q13698	RO:0002436	drug_central	Displacement of [3H]diltiazem from L-type calcium channel of guinea pig striated muscle	biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:897	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:901	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:903	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:903	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:903	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:903	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:903	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:903	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:908	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:908	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:908	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:908	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:908	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:911	biolink:molecularly_interacts_with	UniProtKB:P50579	RO:0002436	drug_central	Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cells	biolink:Association
DrugCentral:911	biolink:molecularly_interacts_with	UniProtKB:P53582	RO:0002436	drug_central	Inhibition of human MetAP1	biolink:Association
DrugCentral:912	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central		biolink:Association
DrugCentral:912	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y4	RO:0002436	drug_central		biolink:Association
DrugCentral:912	biolink:molecularly_interacts_with	UniProtKB:P21731	RO:0002436	drug_central		biolink:Association
DrugCentral:912	biolink:molecularly_interacts_with	UniProtKB:Q13258	RO:0002436	drug_central	Affinity for human Prostaglandin D2 receptor expressed in HEK293 cells	biolink:Association
DrugCentral:912	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central	Affinity for Prostanoid EP4 receptor expressed in CHO cells	biolink:Association
DrugCentral:912	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central	In vitro binding at EP1 human prostaglandin receptor using [3H]PGE-2 as radioligand	biolink:Association
DrugCentral:912	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central	GRAC: human FP probe	biolink:Association
DrugCentral:912	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central	In vitro binding at EP3 human prostaglandin receptor using [3H]PGE-2 as radioligand	biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:Q13258	RO:0002436	drug_central		biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central		biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y4	RO:0002436	drug_central		biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:P21731	RO:0002436	drug_central		biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central	Binding affinity to human prostanoid EP4 receptor by radioligand displacement assay	biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central	Displacement of [3H]PGE2 from human EP1 receptor expressed in HEK293 cells	biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:P43119	RO:0002436	drug_central	Agonist activity at prostanoid IP receptor (unknown origin) by functional assay	biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central	Binding affinity to human prostanoid EP2 receptor by radioligand displacement assay	biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central	Displacement of [3H]PGE2 from human EP3 receptor expressed in HEK293 cells	biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:Q7RTX7	RO:0002436	drug_central	Patch clamp electrophysiology.	biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:Q86XQ3	RO:0002436	drug_central	Patch clamp electrophysiology.	biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:Q8NEC5	RO:0002436	drug_central	Patch clamp electrophysiology	biolink:Association
DrugCentral:913	biolink:molecularly_interacts_with	UniProtKB:Q96P56	RO:0002436	drug_central	Patch clamp electrophysiology.	biolink:Association
DrugCentral:915	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:915	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Mechanism of Action; CHEMBL216; SINGLE PROTEIN	biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central	Displacement of [3H]histamine from human H4R expressed in Sf9 cells co-expressing RGS19, Galphai2 and Gbeta1gamma2 after 60 mins by liquid scintillation counting	biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:916	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:918	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:918	biolink:molecularly_interacts_with	UniProtKB:P22001	RO:0002436	drug_central	Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method	biolink:Association
DrugCentral:920	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:920	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:920	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:920	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:922	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:922	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:922	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:923	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:923	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:923	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP)	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:O95263	RO:0002436	drug_central		biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central	Inhibitory activity against cyclic GMP-phosphodiesterase (PDE V) isolated from porcine aorta.	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q86TP1	RO:0002436	drug_central	Inhibition of human prune assessed as reduction of cAMP-phosphodiesterase activity	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q99808	RO:0002436	drug_central	GRAC: human ENT1 selective inhibitor	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:O43924	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:P16499	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:P18545	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:P35913	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:P51160	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q13956	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q9NP56	RO:0002436	drug_central	GRAC: human PDE7B selective inhibitor	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q13946	RO:0002436	drug_central	Inhibition of human phosphodiesterase 7	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q9NP56	RO:0002436	drug_central	Inhibition of human phosphodiesterase 7	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:P54750	RO:0002436	drug_central	Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricle	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q01064	RO:0002436	drug_central	Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricle	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q14123	RO:0002436	drug_central	Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricle	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:O00408	RO:0002436	drug_central	Inhibition of phosphodiesterase 2 (PDE2) from porcine platelets, range 2.54-4.14	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Inhibition of low Km cyclic cAMP phosphodiesterase PDE III of guinea pig ventricle	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Inhibition of low Km cyclic cAMP phosphodiesterase PDE III of guinea pig ventricle	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q9HCR9	RO:0002436	drug_central	Inhibition of human phosphodiesterase 11	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q9Y233	RO:0002436	drug_central	Inhibitory activity against phosphodiesterase 10	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:O60658	RO:0002436	drug_central	GRAC: human PDE8A selective inhibitor	biolink:Association
DrugCentral:924	biolink:molecularly_interacts_with	UniProtKB:Q7RTT9	RO:0002436	drug_central		biolink:Association
DrugCentral:926	biolink:molecularly_interacts_with	UniProtKB:P48544	RO:0002436	drug_central		biolink:Association
DrugCentral:926	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:926	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:926	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:926	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:926	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:926	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:926	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:926	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:927	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P05091	RO:0002436	drug_central		biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P51681	RO:0002436	drug_central	DRUGMATRIX: Chemokine CCR5 radioligand binding (ligand: [125I] MIP-1alpha)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P25025	RO:0002436	drug_central	DRUGMATRIX: Chemokine CXCR2 (IL-8B) radioligand binding (ligand: [125I] IL-8)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P41597	RO:0002436	drug_central	DRUGMATRIX: Chemokine CCR2B  radioligand binding (ligand: [125I] MCP-1)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P51679	RO:0002436	drug_central	DRUGMATRIX: Chemokine CCR4 radioligand binding (ligand: [125I] TARC)	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:Q99685	RO:0002436	drug_central	Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation counting	biolink:Association
DrugCentral:928	biolink:molecularly_interacts_with	UniProtKB:P30536	RO:0002436	drug_central		biolink:Association
DrugCentral:931	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 4-catalyzed CO2 hydration by stopped flow assay	biolink:Association
DrugCentral:931	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 1-catalyzed CO2 hydration by stopped flow assay	biolink:Association
DrugCentral:931	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 2-catalyzed CO2 hydration by stopped flow assay	biolink:Association
DrugCentral:931	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human CA12 pre-incubated for 15 mins by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:931	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human CA9 pre-incubated for 15 mins by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:934	biolink:molecularly_interacts_with	UniProtKB:Q7Z2W7	RO:0002436	drug_central		biolink:Association
DrugCentral:934	biolink:molecularly_interacts_with	UniProtKB:O75762	RO:0002436	drug_central	Calcium imaging, patch clamp	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5a after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5b after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 13 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 6 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:937	biolink:molecularly_interacts_with	UniProtKB:P21964	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:Q5T3U5	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:939	biolink:molecularly_interacts_with	UniProtKB:Q02643	RO:0002436	drug_central	Displacement of [125I]JV1-42 from GHRH receptor expressed in human MX1 cells	biolink:Association
DrugCentral:942	biolink:molecularly_interacts_with	UniProtKB:O95259	RO:0002436	drug_central		biolink:Association
DrugCentral:942	biolink:molecularly_interacts_with	UniProtKB:O95069	RO:0002436	drug_central		biolink:Association
DrugCentral:942	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Displacement of [3H]dofetilide from hERG expressed in HEK293 cells by SPA	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P0DP23	RO:0002436	drug_central		biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P0DP24	RO:0002436	drug_central		biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P0DP25	RO:0002436	drug_central		biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cells	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:945	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:946	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central		biolink:Association
DrugCentral:946	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:946	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Inhibition of human recombinant MAO-B using tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by fluorometric assay	biolink:Association
DrugCentral:946	biolink:molecularly_interacts_with	UniProtKB:P56817	RO:0002436	drug_central	Inhibition of BACE1	biolink:Association
DrugCentral:946	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Displacement of [3H]DTG from sigma 1 receptor (unknown origin)	biolink:Association
DrugCentral:946	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:946	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central	Non competitive inhibition of human serum BChE using butyrylthiocholine iodide as substrate by Lineweaver-Burk plot analysis	biolink:Association
DrugCentral:946	biolink:molecularly_interacts_with	UniProtKB:Q9Y5N1	RO:0002436	drug_central	Inhibition of histamine H3 receptor	biolink:Association
DrugCentral:946	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity to human adrenergic beta2 receptor	biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P48039	RO:0002436	drug_central	Displacement of 2-[125I]iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells	biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P49286	RO:0002436	drug_central	Inhibition of 2-[125I]iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells	biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Displacement of [125I]RT155 binding in HEK cells expressing human DAT	biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P09172	RO:0002436	drug_central		biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:947	biolink:molecularly_interacts_with	UniProtKB:B2RXH2	RO:0002436	drug_central		biolink:Association
DrugCentral:948	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:948	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 2 by dansylamide (DNSA) competition assay	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibitory activity against catalytic domain of human carbonic anhydrase XII	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of cloned isozyme, human carbonic anhydrase IV	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human carbonic anhydrase13 preincubated for 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VA	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Ki value against human carbonic anhydrase VII	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase IX (hCA IX) by using CO2 hydrase assay method	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human cloned CA1 by CO2 hydration method	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VB	biolink:Association
DrugCentral:949	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of full length human recombinant CA VI	biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:951	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:953	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:953	biolink:molecularly_interacts_with	UniProtKB:O14649	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321613; SINGLE PROTEIN	biolink:Association
DrugCentral:953	biolink:molecularly_interacts_with	UniProtKB:Q9NPC2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321614; SINGLE PROTEIN	biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P03956	RO:0002436	drug_central	DRUGMATRIX: Peptidase, Matrix Metalloproteinase-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Binding affinity against Alpha-2A adrenergic receptor, from human clones.	biolink:Association
DrugCentral:954	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Binding affinity against Alpha-2C adrenergic receptor from human clones.	biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation counting	biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:956	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:957	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central		biolink:Association
DrugCentral:958	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central		biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:P29466	RO:0002436	drug_central	DRUGMATRIX: Protease, Caspase 1 enzyme inhibition (substrate: Ac-YVAD-AMC)	biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:O95255	RO:0002436	drug_central		biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:O14746	RO:0002436	drug_central	Inhibition of telomerase from human COLO201 cell	biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central	Inhibition human placenta topoisomerase 2 assessed as conversion of supercoiled pBR322 DNA to relaxed form	biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central	Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresis	biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Inhibition of GST-tagged Aurora A kinase expressed in insect cells assessed as inhibition of [33P]gamma-ATP incorporation in substrate after 60 mins by scintillation counting	biolink:Association
DrugCentral:960	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central	Inhibitory concentration against Clostridium histolyticum Collagenase	biolink:Association
DrugCentral:961	biolink:molecularly_interacts_with	UniProtKB:P22894	RO:0002436	drug_central		biolink:Association
DrugCentral:961	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central	Inhibition of human MMP2	biolink:Association
DrugCentral:961	biolink:molecularly_interacts_with	UniProtKB:P08254	RO:0002436	drug_central	Inhibition of human MMP3	biolink:Association
DrugCentral:961	biolink:molecularly_interacts_with	UniProtKB:P45452	RO:0002436	drug_central	Inhibition of human MMP13	biolink:Association
DrugCentral:962	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action; CHEMBL231; SINGLE PROTEIN	biolink:Association
DrugCentral:965	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:966	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human Potassium channel HERG expressed in mammalian cells	biolink:Association
DrugCentral:968	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:968	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:968	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:969	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:969	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central		biolink:Association
DrugCentral:971	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331074; PROTEIN FAMILY	biolink:Association
DrugCentral:971	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331074; PROTEIN FAMILY	biolink:Association
DrugCentral:971	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331074; PROTEIN FAMILY	biolink:Association
DrugCentral:971	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331074; PROTEIN FAMILY	biolink:Association
DrugCentral:971	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331074; PROTEIN FAMILY	biolink:Association
DrugCentral:971	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331074; PROTEIN FAMILY	biolink:Association
DrugCentral:971	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331074; PROTEIN FAMILY	biolink:Association
DrugCentral:971	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331074; PROTEIN FAMILY	biolink:Association
DrugCentral:971	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331074; PROTEIN FAMILY	biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Ability to inhibit the reuptake of dopamine at human dopamine transporter	biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Inhibition of human NET	biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Displacement of [3H]citalopram from human SERT transfected in HEK293 cells after 3 hrs by Wallac counting analysis	biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:972	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:973	biolink:molecularly_interacts_with	UniProtKB:P18405	RO:0002436	drug_central		biolink:Association
DrugCentral:973	biolink:molecularly_interacts_with	UniProtKB:P31213	RO:0002436	drug_central		biolink:Association
DrugCentral:973	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:974	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central		biolink:Association
DrugCentral:975	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:975	biolink:molecularly_interacts_with	UniProtKB:Q9Y466	RO:0002436	drug_central	orthogonal direct binding assay	biolink:Association
DrugCentral:976	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central		biolink:Association
DrugCentral:976	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Mechanism of Action; CHEMBL241; SINGLE PROTEIN	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of human ABCB1-mediated rhodamine 123 efflux in mouse L5178 cells expressing human MDR1 after 20 mins by FACS analysis	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Compound is evaluated for in vitro receptor binding affinity against 5-hydroxytryptamine 1A receptor	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M1	biolink:Association
DrugCentral:977	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Compound is evaluated for in vitro receptor binding affinity against Dopamine receptor D2	biolink:Association
DrugCentral:979	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:982	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Mechanism of Action; CHEMBL220; SINGLE PROTEIN	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central	DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P41968	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P49146	RO:0002436	drug_central	DRUGMATRIX: Neuropeptide Y Y2 radioligand binding (ligand: [125I] Peptide YY)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P40925	RO:0002436	drug_central	Inhibition of malate dehydrogenase (MDH)	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P05093	RO:0002436	drug_central	In vitro inhibition of human Cytochrome P450 17A1 activity	biolink:Association
DrugCentral:983	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central		biolink:Association
DrugCentral:986	biolink:molecularly_interacts_with	UniProtKB:Q05932	RO:0002436	drug_central		biolink:Association
DrugCentral:986	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central		biolink:Association
DrugCentral:987	biolink:molecularly_interacts_with	UniProtKB:Q16739	RO:0002436	drug_central		biolink:Association
DrugCentral:988	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition constant determined against Acetylcholinesterase (AChE) receptor.	biolink:Association
DrugCentral:989	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:990	biolink:molecularly_interacts_with	UniProtKB:P11926	RO:0002436	drug_central		biolink:Association
DrugCentral:992	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central	HEK-293 cells stably expressing hCav3.2 T-type Ca2+ channels	biolink:Association
DrugCentral:992	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:992	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:995	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:995	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:995	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:995	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central	GRAC: human 5-HT1B probe	biolink:Association
DrugCentral:995	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central	GRAC: human 5-HT1D probe	biolink:Association
DrugCentral:996	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Inhibitory activity against Fibroblast growth factor receptor 3	biolink:Association
DrugCentral:996	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus	biolink:Association
DrugCentral:996	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Inhibitory activity against Platelet-derived growth factor receptor alpha	biolink:Association
DrugCentral:997	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:997	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:997	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:999	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1001	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1001	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1001	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1001	biolink:molecularly_interacts_with	UniProtKB:O75884	RO:0002436	drug_central	Displacement of fluorophosphate-rhodamine from RBBP9 transfected in human HEK293T cells proteomes after 30 mins by SDS-PAGE gel fluorescence assay	biolink:Association
DrugCentral:1005	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central		biolink:Association
DrugCentral:1006	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central		biolink:Association
DrugCentral:1007	biolink:molecularly_interacts_with	UniProtKB:Q8IWT1	RO:0002436	drug_central		biolink:Association
DrugCentral:1007	biolink:molecularly_interacts_with	UniProtKB:Q9NY72	RO:0002436	drug_central		biolink:Association
DrugCentral:1007	biolink:molecularly_interacts_with	UniProtKB:O60939	RO:0002436	drug_central		biolink:Association
DrugCentral:1007	biolink:molecularly_interacts_with	UniProtKB:Q07699	RO:0002436	drug_central		biolink:Association
DrugCentral:1007	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1008	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:1009	biolink:molecularly_interacts_with	UniProtKB:P57789	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331041; SINGLE PROTEIN	biolink:Association
DrugCentral:1009	biolink:molecularly_interacts_with	UniProtKB:Q7Z418	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331042; SINGLE PROTEIN	biolink:Association
DrugCentral:1009	biolink:molecularly_interacts_with	UniProtKB:O14649	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321613; SINGLE PROTEIN	biolink:Association
DrugCentral:1009	biolink:molecularly_interacts_with	UniProtKB:Q9NPC2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321614; SINGLE PROTEIN	biolink:Association
DrugCentral:1009	biolink:molecularly_interacts_with	UniProtKB:O95069	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321615; SINGLE PROTEIN	biolink:Association
DrugCentral:1009	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:1013	biolink:molecularly_interacts_with	UniProtKB:P21281	RO:0002436	drug_central	Inhibition of maltose binding protein-fused human V-ATPase subunit B2 binding to F-actin	biolink:Association
DrugCentral:1014	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of canine heart Phosphodiesterase 4	biolink:Association
DrugCentral:1014	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibition of canine heart Phosphodiesterase 4	biolink:Association
DrugCentral:1014	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Inhibition of canine heart Phosphodiesterase 4	biolink:Association
DrugCentral:1014	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of canine heart Phosphodiesterase 4	biolink:Association
DrugCentral:1014	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central		biolink:Association
DrugCentral:1015	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central	Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligand	biolink:Association
DrugCentral:1015	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells	biolink:Association
DrugCentral:1015	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Binding affinity to human adenosine A2A receptor	biolink:Association
DrugCentral:1015	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	Displacement of [3H]CPX from human adenosine A3 receptor expressed in CHO cells	biolink:Association
DrugCentral:1015	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central		biolink:Association
DrugCentral:1016	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central		biolink:Association
DrugCentral:1016	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central		biolink:Association
DrugCentral:1016	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:1016	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:1016	biolink:molecularly_interacts_with	UniProtKB:P43119	RO:0002436	drug_central		biolink:Association
DrugCentral:1018	biolink:molecularly_interacts_with	UniProtKB:P21964	RO:0002436	drug_central		biolink:Association
DrugCentral:1018	biolink:molecularly_interacts_with	UniProtKB:Q9HC97	RO:0002436	drug_central		biolink:Association
DrugCentral:1021	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central		biolink:Association
DrugCentral:1021	biolink:molecularly_interacts_with	UniProtKB:Q00796	RO:0002436	drug_central	Inhibition sorbitol dehydrogenase by spectrophotometric analysis	biolink:Association
DrugCentral:1021	biolink:molecularly_interacts_with	UniProtKB:P14550	RO:0002436	drug_central	Inhibition of N-terminal 6His-tagged human aldehyde reductase expressed in Escherichia coli BL21(DE3) mediated D-glucuronate reduction	biolink:Association
DrugCentral:1021	biolink:molecularly_interacts_with	UniProtKB:O60218	RO:0002436	drug_central	Inhibition of reductase activity of N-terminal 6His-tagged AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as inhibition of NADPH linked pyridine-3-aldehyde reduction	biolink:Association
DrugCentral:1022	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:1022	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1022	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1022	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1024	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1027	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1027	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1027	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1027	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1027	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1027	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1027	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1027	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1027	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:1027	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1028	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:1028	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1028	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1028	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1028	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1028	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells	biolink:Association
DrugCentral:1028	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity to human adrenergic beta2 receptor	biolink:Association
DrugCentral:1028	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding affinity against alpha-1 adrenergic receptor in guinea pig cerebral cortical membranes by displacement of [3H]- WB-4101	biolink:Association
DrugCentral:1028	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1028	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1030	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1032	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:1032	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Antagonist activity at glucocorticoid receptor (unknown origin) by NH Pro assay	biolink:Association
DrugCentral:1034	biolink:molecularly_interacts_with	UniProtKB:P43119	RO:0002436	drug_central		biolink:Association
DrugCentral:1034	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central		biolink:Association
DrugCentral:1034	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:1034	biolink:molecularly_interacts_with	UniProtKB:Q9H244	RO:0002436	drug_central		biolink:Association
DrugCentral:1037	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central	Tested for Angiotensin II receptor, type 1 affinity in the absence of bovine serum albumin (BSA)	biolink:Association
DrugCentral:1040	biolink:molecularly_interacts_with	UniProtKB:P05106	RO:0002436	drug_central	platelet aggregation inhibition in plasma anticoagulated PPACK	biolink:Association
DrugCentral:1040	biolink:molecularly_interacts_with	UniProtKB:P08514	RO:0002436	drug_central	platelet aggregation inhibition in plasma anticoagulated PPACK	biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1042	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central	Displacement of [3H]carboxytryptamine from recombinant human 5-HT1B receptor expressed in HEK cells by scintillation counting	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central	Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1D receptor	biolink:Association
DrugCentral:1043	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central	Displacement of [3H]LSD from 5-HT5A receptor after 1.5 hrs by scintillation counting	biolink:Association
DrugCentral:1044	biolink:molecularly_interacts_with	UniProtKB:O00206	RO:0002436	drug_central		biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central		biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Binding constant for JNK3 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(D835Y) kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(H396P)-phosphorylated kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q6DT37	RO:0002436	drug_central	Binding constant for DMPK2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central	Binding constant for FLT1 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P45984	RO:0002436	drug_central	Binding constant for JNK2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P32298	RO:0002436	drug_central	Binding constant for GRK4 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Binding constant for VEGFR2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding constant for MAP3K2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding constant for ULK3 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q92630	RO:0002436	drug_central	Binding constant for DYRK2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Binding constant for PDGFRA kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET(Y1235D) kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P49674	RO:0002436	drug_central	Binding constant for CSNK1E kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P21860	RO:0002436	drug_central	Binding constant for ERBB3 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Average Binding Constant for RIPK2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central	Binding constant for EPHB4 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for SIK2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q52WX2	RO:0002436	drug_central	Binding constant for SBK1 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Binding constant for AURKA kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P48730	RO:0002436	drug_central	Binding constant for full-length CSNK1D	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P19525	RO:0002436	drug_central	Binding constant for PRKR kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P31152	RO:0002436	drug_central	Binding constant for ERK4 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9UHD2	RO:0002436	drug_central	Binding constant for TBK1 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P35916	RO:0002436	drug_central	Binding constant for FLT4 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q96D53	RO:0002436	drug_central	Binding constant for full-length ADCK4	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9BUB5	RO:0002436	drug_central	Binding constant for full-length MKNK1	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O43293	RO:0002436	drug_central	Binding constant for DAPK3 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P29322	RO:0002436	drug_central	Binding constant for EPHA8 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P33981	RO:0002436	drug_central	Binding constant for TTK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Binding constant for EPHA3 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O94768	RO:0002436	drug_central	Binding constant for DRAK2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Binding constant for PLK4 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q2M2I8	RO:0002436	drug_central	Binding constant for AAK1 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9P2K8	RO:0002436	drug_central	Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(M918T) kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q09013	RO:0002436	drug_central	Binding constant for DMPK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q06418	RO:0002436	drug_central	Binding constant for TYRO3 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9H1R3	RO:0002436	drug_central	Binding constant for MYLK2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central	Binding constant for LTK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central	Binding constant for CSK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q59H18	RO:0002436	drug_central	Binding constant for full-length TNNI3K	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	Binding constant for ERBB2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Binding constant for full-length AURKC	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9UPE1	RO:0002436	drug_central	Binding constant for SRPK3 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Average Binding Constant for FGFR2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Binding constant for ALK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O14578	RO:0002436	drug_central	Binding constant for CIT kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding constant for HIPK4 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q8NI60	RO:0002436	drug_central	Binding constant for ADCK3 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding constant for MAP3K3 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding constant for MINK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q5S007	RO:0002436	drug_central	Binding constant for LRRK2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q8TBX8	RO:0002436	drug_central	Binding constant for PIP5K2C kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9NRP7	RO:0002436	drug_central	Binding constant for STK36 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(V559D,T670I) kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central	Binding constant for ERBB4 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9UEE5	RO:0002436	drug_central	Binding constant for DRAK1 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Binding constant for EPHA6 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q13557	RO:0002436	drug_central	Binding constant for CAMK2D kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:O75676	RO:0002436	drug_central	Binding constant for RPS6KA4(Kin.Dom.2 - N-terminal) kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q96GD4	RO:0002436	drug_central	Binding constant for AURKB kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q9HBH9	RO:0002436	drug_central	Binding constant for MKNK2 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Binding constant for TYK2(JH2domain-pseudokinase) kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q15375	RO:0002436	drug_central	Binding constant for EPHA7 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P57078	RO:0002436	drug_central	Binding constant for RIPK4 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P54756	RO:0002436	drug_central	Binding constant for EPHA5 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central	Binding constant for EPHB1 kinase domain	biolink:Association
DrugCentral:1045	biolink:molecularly_interacts_with	UniProtKB:Q13470	RO:0002436	drug_central	Binding constant for full-length TNK1	biolink:Association
DrugCentral:1048	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1048	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG expressed in HEK cells	biolink:Association
DrugCentral:1048	biolink:molecularly_interacts_with	UniProtKB:O43193	RO:0002436	drug_central	In vitro binding affinity towards human motilin receptor	biolink:Association
DrugCentral:1048	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:1052	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:1053	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1053	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1053	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1053	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1053	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1053	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1054	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1055	biolink:molecularly_interacts_with	UniProtKB:P20648	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095173; PROTEIN COMPLEX	biolink:Association
DrugCentral:1055	biolink:molecularly_interacts_with	UniProtKB:P51164	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095173; PROTEIN COMPLEX	biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1056	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:Q12791	RO:0002436	drug_central		biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:P08842	RO:0002436	drug_central	Inhibition of steroid sulfatase activity of JEG-3 cells	biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:O95718	RO:0002436	drug_central	Inhibition of human ERbeta	biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:P11474	RO:0002436	drug_central	Inhibition of human ERalpha	biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Inhibitory activity against AR	biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:Q99527	RO:0002436	drug_central		biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central		biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1057	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:1058	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1058	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1058	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1058	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1058	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1058	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1058	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	biolink:Association
DrugCentral:1058	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1058	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1059	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Mechanism of Action; CHEMBL206; SINGLE PROTEIN	biolink:Association
DrugCentral:1064	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Mechanism of Action; CHEMBL206; SINGLE PROTEIN	biolink:Association
DrugCentral:1066	biolink:molecularly_interacts_with	UniProtKB:P18031	RO:0002436	drug_central	Inhibition of recombinant PTP1B	biolink:Association
DrugCentral:1066	biolink:molecularly_interacts_with	UniProtKB:P29350	RO:0002436	drug_central	Inhibition of recombinant SHP1	biolink:Association
DrugCentral:1066	biolink:molecularly_interacts_with	UniProtKB:Q06124	RO:0002436	drug_central	Binding affinity to recombinant SHP2 by surface plasmon response	biolink:Association
DrugCentral:1066	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Mechanism of Action; CHEMBL242; SINGLE PROTEIN	biolink:Association
DrugCentral:1067	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Agonist activity at ER-beta (unknown origin) transfected in HEK293T cells after 24 hrs by Steady-Glo luciferase reporter gene assay	biolink:Association
DrugCentral:1067	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	biolink:Association
DrugCentral:1067	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1067	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1067	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1067	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Displacement of [3H]Ro-154513 from benzodiazepine binding site of GABAA alpha-4-beta-2-gamma-2 receptor expressed in HEK293T cells	biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Displacement of [3H]Ro-151788 from benzodiazepine binding site of GABAA alpha-2-beta-2-gamma-2 receptor expressed in HEK293T cells	biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Displacement of [3H]Ro15-1788 from benzodiazepine binding site of GABAA alpha-1-beta-2-gamma-2 receptor expressed in HEK293T cells	biolink:Association
DrugCentral:1068	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Displacement of [3H]Ro-151788 from benzodiazepine binding site of GABAA alpha-3-beta-2-gamma-2 receptor expressed in HEK293T cells	biolink:Association
DrugCentral:1071	biolink:molecularly_interacts_with	UniProtKB:Q13621	RO:0002436	drug_central		biolink:Association
DrugCentral:1071	biolink:molecularly_interacts_with	UniProtKB:P09211	RO:0002436	drug_central	Inhibition of GST P1-1 in human HL60 cell lysate	biolink:Association
DrugCentral:1071	biolink:molecularly_interacts_with	UniProtKB:Q14376	RO:0002436	drug_central	Inhibition of human GalE by HPAEC assay	biolink:Association
DrugCentral:1071	biolink:molecularly_interacts_with	UniProtKB:P08263	RO:0002436	drug_central	Inhibition of GST A1-1	biolink:Association
DrugCentral:1073	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1073	biolink:molecularly_interacts_with	UniProtKB:P20815	RO:0002436	drug_central		biolink:Association
DrugCentral:1073	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1073	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1073	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1076	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central		biolink:Association
DrugCentral:1076	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1076	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central		biolink:Association
DrugCentral:1076	biolink:molecularly_interacts_with	UniProtKB:P23416	RO:0002436	drug_central		biolink:Association
DrugCentral:1076	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:1076	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:1078	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1078	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1078	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Binding affinity to ERbeta	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1082	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1084	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1084	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1086	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1086	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plot	biolink:Association
DrugCentral:1086	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central	Inhibitory activity against Equine Butyrylcholinesterase	biolink:Association
DrugCentral:1086	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:1087	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central		biolink:Association
DrugCentral:1088	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1088	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1088	biolink:molecularly_interacts_with	UniProtKB:Q01118	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1088	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1088	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1088	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1088	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1088	biolink:molecularly_interacts_with	UniProtKB:Q9UI33	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1088	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1088	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VA	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	In vitro binding to human erythrocyte carbonic anhydrase was determined by fluorescence competition assay employing the fluorescent CA inhibitor dansylamide	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant full length CA14 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Binding affinity to human recombinant CA7 at 37 degC and pH 7.0 by thermal shift assay	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Ki value against human carbonic anhydrase XII (hCA XII)	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibitory activity against human tumor-associated transmembrane carbonic anhydrase IX.	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase IV (hCAIV)	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Binding affinity to human recombinant CA1 at 37 degC and pH 7.0 by thermal shift assay	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VB	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Binding affinity to human recombinant CA13 at 37 degC and pH 7.0 by thermal shift assay	biolink:Association
DrugCentral:1089	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Binding affinity to human recombinant carbonic anhydrase 6 expressed in Escherichia coli Rosetta2 (DE3) by thermal shift assay	biolink:Association
DrugCentral:1091	biolink:molecularly_interacts_with	UniProtKB:Q9BQB6	RO:0002436	drug_central		biolink:Association
DrugCentral:1094	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1094	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1094	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1094	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	biolink:Association
DrugCentral:1094	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:1094	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1094	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Mechanism of Action; CHEMBL1871; SINGLE PROTEIN	biolink:Association
DrugCentral:1095	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1095	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:1095	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:1097	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central		biolink:Association
DrugCentral:1097	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central		biolink:Association
DrugCentral:1097	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1100	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity towards sigma opioid receptor in guinea pig cerebral homogenate using [3H]DTG as radioligand	biolink:Association
DrugCentral:1101	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1102	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1103	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:1103	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition of COX2 in human whole blood assessed as inhibition of TXB2 production by radioimmunoassay	biolink:Association
DrugCentral:1107	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central	Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligand	biolink:Association
DrugCentral:1109	biolink:molecularly_interacts_with	UniProtKB:P15538	RO:0002436	drug_central	Inhibition of human CYP11B1 expressed in chinese hamster V79 cells	biolink:Association
DrugCentral:1109	biolink:molecularly_interacts_with	UniProtKB:P19099	RO:0002436	drug_central	Inhibition of human CYP11B2 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrate	biolink:Association
DrugCentral:1109	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1109	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1109	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1109	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:1109	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:1109	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:1109	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Activity at human GABAA alpha-1-beta-2-gamma-2s receptor expressed in HEK293 cells assessed as effect on GABA-induced current at 3 uM by whole cell patch-clamp technique	biolink:Association
DrugCentral:1110	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1110	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:1110	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1111	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1111	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1111	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1111	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1112	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central	Note: enzyme subunit is not specified in the referenced article	biolink:Association
DrugCentral:1112	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:1112	biolink:molecularly_interacts_with	UniProtKB:O15438	RO:0002436	drug_central		biolink:Association
DrugCentral:1112	biolink:molecularly_interacts_with	UniProtKB:O95255	RO:0002436	drug_central		biolink:Association
DrugCentral:1112	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:1112	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:1112	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:1112	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1113	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central		biolink:Association
DrugCentral:1113	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1113	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of Prostaglandin G/H synthase 1 was measured by the inhibition of PGE-2 produced by microsomes from U937 cells at subsaturating arachidonic acid conc.	biolink:Association
DrugCentral:1113	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	Inhibitory concentration against p38 alpha MAP kinase calculated by CoMFA model; FlexX score = -18.6kcal/mol 	biolink:Association
DrugCentral:1115	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central	Inhibition of MRP2 expressed in MDCK2 cells assessed as cell growth inhibition by calcein and pheophorbide A efflux assays	biolink:Association
DrugCentral:1115	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of MDR1 expressed in MDCK2 cells assessed as inhibition of cell proliferation by calcein and pheophorbide A efflux assays	biolink:Association
DrugCentral:1115	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central	Inhibition of MRP1 expressed in MDCK2 cells assessed as cell growth inhibition by calcein and pheophorbide A efflux assays	biolink:Association
DrugCentral:1115	biolink:molecularly_interacts_with	UniProtKB:O15438	RO:0002436	drug_central	Inhibition of MRP3 expressed in MDCK2 cells assessed as cell growth inhibition by calcein and pheophorbide A efflux assays	biolink:Association
DrugCentral:1115	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central	Inhibition of BCRP expressed in MDCK2 cells assessed as cell growth inhibition by calcein and pheophorbide A efflux assays	biolink:Association
DrugCentral:1116	biolink:molecularly_interacts_with	UniProtKB:P48443	RO:0002436	drug_central		biolink:Association
DrugCentral:1116	biolink:molecularly_interacts_with	UniProtKB:P10276	RO:0002436	drug_central		biolink:Association
DrugCentral:1118	biolink:molecularly_interacts_with	UniProtKB:P62942	RO:0002436	drug_central		biolink:Association
DrugCentral:1118	biolink:molecularly_interacts_with	UniProtKB:P42345	RO:0002436	drug_central		biolink:Association
DrugCentral:1118	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1122	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central		biolink:Association
DrugCentral:1122	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1123	biolink:molecularly_interacts_with	UniProtKB:P43220	RO:0002436	drug_central	Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cells	biolink:Association
DrugCentral:1125	biolink:molecularly_interacts_with	UniProtKB:Q9UHC9	RO:0002436	drug_central	Measure of ezetimibe glucuronide binding to NPC1L1	biolink:Association
DrugCentral:1126	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Competitive inhibition of human aromatase using dibenzylfluorescein substrate after 10 mins preincubation measured every 10 sec for 5 mins by Michaelis-Menten and Dixon plot analysis	biolink:Association
DrugCentral:1126	biolink:molecularly_interacts_with	UniProtKB:P15538	RO:0002436	drug_central	Inhibition of human CYP11B1 expressed in V79MZh cells using [14C]-11-deoxycorticosterone as substrate by HPTLC/phosphoimaging method	biolink:Association
DrugCentral:1126	biolink:molecularly_interacts_with	UniProtKB:P19099	RO:0002436	drug_central	Inhibition of human CYP11B2 expressed in V79MZh cells using [14C]-11-deoxycorticosterone as substrate by HPTLC/phosphoimaging method	biolink:Association
DrugCentral:1129	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:1129	biolink:molecularly_interacts_with	UniProtKB:P07900	RO:0002436	drug_central		biolink:Association
DrugCentral:1129	biolink:molecularly_interacts_with	UniProtKB:O75751	RO:0002436	drug_central	Inhibition of human OCT3-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1129	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1129	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1129	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1130	biolink:molecularly_interacts_with	UniProtKB:Q9Y466	RO:0002436	drug_central	orthogonal direct binding assay	biolink:Association
DrugCentral:1132	biolink:molecularly_interacts_with	UniProtKB:P13500	RO:0002436	drug_central	Inhibition of MCP1-mediated human THP cell migration	biolink:Association
DrugCentral:1132	biolink:molecularly_interacts_with	UniProtKB:Q13464	RO:0002436	drug_central	Inhibition of ROCK-1	biolink:Association
DrugCentral:1132	biolink:molecularly_interacts_with	UniProtKB:Q02156	RO:0002436	drug_central	Inhibition of PKCepsilon	biolink:Association
DrugCentral:1132	biolink:molecularly_interacts_with	UniProtKB:O75582	RO:0002436	drug_central	Inhibition of His-tagged human MSK1 expressed in Sf9 cells	biolink:Association
DrugCentral:1132	biolink:molecularly_interacts_with	UniProtKB:Q15746	RO:0002436	drug_central	Inhibition of MLCK by HTRF assay	biolink:Association
DrugCentral:1132	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central	Displacement of fluorescent-ARC-1063 from His6-tagged recombinant human ROCK2 by luminescence intensity assay	biolink:Association
DrugCentral:1132	biolink:molecularly_interacts_with	UniProtKB:Q16513	RO:0002436	drug_central	Inhibition of PKN2	biolink:Association
DrugCentral:1132	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Displacement of [3H]dofetilide from human ERG	biolink:Association
DrugCentral:1132	biolink:molecularly_interacts_with	UniProtKB:Q16512	RO:0002436	drug_central	Inhibition of Protein kinase C related kinase 1 (PRK1)	biolink:Association
DrugCentral:1132	biolink:molecularly_interacts_with	UniProtKB:P17612	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Protein Kinase A Activity Assay Measured in Biochemical System Using Plate Reader - 2052-04_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2689]	biolink:Association
DrugCentral:1137	biolink:molecularly_interacts_with	UniProtKB:P47989	RO:0002436	drug_central		biolink:Association
DrugCentral:1137	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1140	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central		biolink:Association
DrugCentral:1140	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central		biolink:Association
DrugCentral:1141	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:1141	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central		biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assay	biolink:Association
DrugCentral:1142	biolink:molecularly_interacts_with	UniProtKB:P13569	RO:0002436	drug_central		biolink:Association
DrugCentral:1145	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1145	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1148	biolink:molecularly_interacts_with	UniProtKB:P41180	RO:0002436	drug_central	Positive allosteric modulation of human CaSR transfected in CHO cells after 5 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:1148	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in CHO cells by liquid scintillation counting	biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1150	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1152	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1152	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1152	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1152	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1152	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:1152	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1152	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1152	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:1152	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	In vitro activation of human peroxisome proliferator activated receptor gamma (PPAR gamma)	biolink:Association
DrugCentral:1152	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Inhibition of human PPARalpha receptor by scintillation proximity assay	biolink:Association
DrugCentral:1153	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1153	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1153	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Affinity towards Dopamine receptor D2	biolink:Association
DrugCentral:1153	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells	biolink:Association
DrugCentral:1153	biolink:molecularly_interacts_with	UniProtKB:B2RXH2	RO:0002436	drug_central	Non-competitive inhibition of JMJD2E relative to alpha-ketoglutarate	biolink:Association
DrugCentral:1153	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Activity at alpha-1 adrenergic receptor in rabbit aorta rings	biolink:Association
DrugCentral:1153	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Activity at alpha-1 adrenergic receptor in rabbit aorta rings	biolink:Association
DrugCentral:1153	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Activity at alpha-1 adrenergic receptor in rabbit aorta rings	biolink:Association
DrugCentral:1153	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:1154	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1154	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1154	biolink:molecularly_interacts_with	UniProtKB:Q8N695	RO:0002436	drug_central		biolink:Association
DrugCentral:1155	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1164	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1164	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Binding affinity against Opioid receptor kappa 1	biolink:Association
DrugCentral:1164	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Binding affinity against Opioid receptor delta 1 in guinea pig brain membranes	biolink:Association
DrugCentral:1164	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against potassium channel HERG	biolink:Association
DrugCentral:1164	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Displacement of [3H]2-BFI (1 nM) from imidazoline receptor I-2 in human brain	biolink:Association
DrugCentral:1164	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Displacement of [3H]2-BFI (1 nM) from imidazoline receptor I-2 in human brain	biolink:Association
DrugCentral:1165	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y4	RO:0002436	drug_central	Displacement of[3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cells	biolink:Association
DrugCentral:1170	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1170	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1170	biolink:molecularly_interacts_with	UniProtKB:P46721	RO:0002436	drug_central		biolink:Association
DrugCentral:1170	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG in MCF7 cells	biolink:Association
DrugCentral:1171	biolink:molecularly_interacts_with	UniProtKB:P31213	RO:0002436	drug_central		biolink:Association
DrugCentral:1171	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1171	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1171	biolink:molecularly_interacts_with	UniProtKB:P18405	RO:0002436	drug_central		biolink:Association
DrugCentral:1171	biolink:molecularly_interacts_with	UniProtKB:P14060	RO:0002436	drug_central	Binding affinity for 3-beta-hydroxysteroid dehydrogenase	biolink:Association
DrugCentral:1175	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:1175	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093863; PROTEIN FAMILY	biolink:Association
DrugCentral:1175	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093863; PROTEIN FAMILY	biolink:Association
DrugCentral:1175	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093863; PROTEIN FAMILY	biolink:Association
DrugCentral:1175	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093863; PROTEIN FAMILY	biolink:Association
DrugCentral:1175	biolink:molecularly_interacts_with	UniProtKB:Q13946	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111411; PROTEIN FAMILY	biolink:Association
DrugCentral:1175	biolink:molecularly_interacts_with	UniProtKB:Q9NP56	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111411; PROTEIN FAMILY	biolink:Association
DrugCentral:1175	biolink:molecularly_interacts_with	UniProtKB:O60658	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363067; PROTEIN FAMILY	biolink:Association
DrugCentral:1175	biolink:molecularly_interacts_with	UniProtKB:O95263	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363067; PROTEIN FAMILY	biolink:Association
DrugCentral:1176	biolink:molecularly_interacts_with	UniProtKB:Q96RP8	RO:0002436	drug_central		biolink:Association
DrugCentral:1176	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central		biolink:Association
DrugCentral:1176	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central		biolink:Association
DrugCentral:1176	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:1176	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Inhibition of human heart sodium channel Nav1.5 by patch-clamp method	biolink:Association
DrugCentral:1176	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human Potassium channel HERG expressed in mammalian cells	biolink:Association
DrugCentral:1178	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1178	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1180	biolink:molecularly_interacts_with	UniProtKB:P21964	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1183	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1183	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central		biolink:Association
DrugCentral:1184	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central		biolink:Association
DrugCentral:1187	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Binding affinity to human His-tagged CYP51 expressed in Escherichia coli	biolink:Association
DrugCentral:1187	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1187	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:1187	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central		biolink:Association
DrugCentral:1188	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1189	biolink:molecularly_interacts_with	UniProtKB:P09884	RO:0002436	drug_central		biolink:Association
DrugCentral:1189	biolink:molecularly_interacts_with	UniProtKB:P31350	RO:0002436	drug_central	Inhibition of ADP reduction by ribonucleotide reductase from HeLa cells	biolink:Association
DrugCentral:1189	biolink:molecularly_interacts_with	UniProtKB:P23921	RO:0002436	drug_central	Inhibition of ADP reduction by ribonucleotide reductase from HeLa cells	biolink:Association
DrugCentral:1191	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:1191	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:1191	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:Q9NYV8	RO:0002436	drug_central	calcium imaging in ransfected human embryonic kidney (HEK)-293T	biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:P05164	RO:0002436	drug_central	Inhibition of chlorinating activity of recombinant myeloperoxidase by taurine assay	biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:Q8TD43	RO:0002436	drug_central	GRAC: human TRPM4 blocker	biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:O94759	RO:0002436	drug_central	Inhibition of human recombinant TRPM2	biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central	In vitro inhibition of rabbit lens aldose reductase.	biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:Q9NZQ8	RO:0002436	drug_central		biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central		biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:P52895	RO:0002436	drug_central		biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:Q04828	RO:0002436	drug_central		biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:O60218	RO:0002436	drug_central		biolink:Association
DrugCentral:1193	biolink:molecularly_interacts_with	UniProtKB:Q6UVM3	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Displacement of [3H]Ro-154513 from benzodiazepine binding site of GABAA alpha-4-beta-2-gamma-2 receptor expressed in HEK293T cells	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central		biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Binding affinity to GABAA alpha-5-beta-2-gamma-2 receptor	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Displacement of [3H]flumazenil from bovine benzodiazepine receptor GABA-A channel of brain membranes	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Binding affinity to GABAA alpha-1-beta-2-gamma-2 receptor	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Displacement of [3H]Ro-151788 from benzodiazepine binding site of GABAA alpha-2-beta-2-gamma-2 receptor expressed in HEK293T cells	biolink:Association
DrugCentral:1195	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Displacement of [3H]Ro-151788 from benzodiazepine binding site of GABAA alpha-3-beta-2-gamma-2 receptor expressed in HEK293T cells	biolink:Association
DrugCentral:1198	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central	DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central	Inhibition of T-type Cav3.2 channel	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:Q9P0X4	RO:0002436	drug_central	Inhibition of T-type Cav3.3 channel	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central	Inhibition of T-type Cav3.1 channel	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligand	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Binding affinity against delta opiate receptor using [3H]DPDPE	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Binding affinity against mu opioid receptor using [3H]DAMGO	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:Q00975	RO:0002436	drug_central	Inhibition of calcium channel Cav2.2 in IMR32 cells	biolink:Association
DrugCentral:1200	biolink:molecularly_interacts_with	UniProtKB:Q9Y256	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Human Ras-Converting Enzyme Inhibition Assay Measured in Biochemical System Using Plate Reader - 2034-04_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2618]	biolink:Association
DrugCentral:1201	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Assay using recombinant GABA<sub>A</sub> channels with subunit composition; &alpha;3&beta;1&gamma;2.	biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Assay using recombinant GABA<sub>A</sub> channels with subunit composition; &alpha;5&beta;1&gamma;2.	biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Assay using recombinant GABA<sub>A</sub> channels with subunit composition; &alpha;1&beta;3&gamma;2.	biolink:Association
DrugCentral:1202	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Assay using recombinant GABA<sub>A</sub> channels with subunit composition; &alpha;2&beta;1&gamma;2.	biolink:Association
DrugCentral:1204	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1205	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1207	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1207	biolink:molecularly_interacts_with	UniProtKB:Q99873	RO:0002436	drug_central	Inhibition of human recombinant GST-PRMT1 expressed in BL21 cells	biolink:Association
DrugCentral:1208	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of AChE	biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	The compound was tested for affinity towards sigma-3 receptor	biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:Q9Y5N1	RO:0002436	drug_central	Binding affinity to human histamine H3 receptor	biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1209	biolink:molecularly_interacts_with	UniProtKB:Q7RTT9	RO:0002436	drug_central		biolink:Association
DrugCentral:1210	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Displacement of [3H]DHT from human AR expressed in MDA-MB-453 cells	biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Note that this assay uses the <i>cis</i> form of the compound, whereas the approved drug is a racemic mixture of <i>cis</i> and <i>trans</i> molecules.	biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1211	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	The compound was tested for affinity towards sigma-3 receptor	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1212	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1213	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Mechanism of Action; CHEMBL217; SINGLE PROTEIN	biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1214	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1215	biolink:molecularly_interacts_with	UniProtKB:O43526	RO:0002436	drug_central		biolink:Association
DrugCentral:1215	biolink:molecularly_interacts_with	UniProtKB:O43525	RO:0002436	drug_central		biolink:Association
DrugCentral:1216	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:1217	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1218	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:1218	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1218	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1218	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1219	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central	Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one as substrate after 1 hr by fluorimetric analysis	biolink:Association
DrugCentral:1219	biolink:molecularly_interacts_with	UniProtKB:P12104	RO:0002436	drug_central	Displacement of 1-anilinonaphthalene-8-sulphonic acid from I-FABP	biolink:Association
DrugCentral:1219	biolink:molecularly_interacts_with	UniProtKB:P52895	RO:0002436	drug_central	Inhibition of human recombinant N-terminal His6-tagged AKR1C2 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one as substrate after 1 hr by fluorimetric analysis	biolink:Association
DrugCentral:1219	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1219	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P41146	RO:0002436	drug_central	Displacement of [125I]nociceptin from human NOP expressed in CHO cells	biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against IKr potassium channel	biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in CHO cells by liquid scintillation counting	biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation counting	biolink:Association
DrugCentral:1222	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:1223	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1223	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Binding affinity against GST-hARLBD was measured in SC-3 cell by using [3H]testosterone as radioligand	biolink:Association
DrugCentral:1223	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central		biolink:Association
DrugCentral:1225	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1225	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:1225	biolink:molecularly_interacts_with	UniProtKB:P47712	RO:0002436	drug_central		biolink:Association
DrugCentral:1225	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:1227	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central	Agonist activity at PXR (unknown origin) expressed in human HepG2 cells assessed as induction of CYP3A4 transactivation after 16 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:1227	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assay	biolink:Association
DrugCentral:1229	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1229	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central	Inhibitory concentration against 3-hydroxy-3-methylglutaryl-CoA reductase	biolink:Association
DrugCentral:1229	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:1230	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity to sigma 1 receptor	biolink:Association
DrugCentral:1230	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	In vitro competitive binding versus [N-methyl-3H]WIN-35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)	biolink:Association
DrugCentral:1230	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1230	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central		biolink:Association
DrugCentral:1230	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1231	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central	Inhibitory constant of thymidylate synthase was determined in human AML cells	biolink:Association
DrugCentral:1232	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central		biolink:Association
DrugCentral:1232	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central	Tested for the inhibition of [14C]-DDATHF influx in CCRF-CEM cells of human leukemic lymphoblast	biolink:Association
DrugCentral:1233	biolink:molecularly_interacts_with	UniProtKB:P00325	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363044; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1233	biolink:molecularly_interacts_with	UniProtKB:P00326	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363044; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1233	biolink:molecularly_interacts_with	UniProtKB:P07327	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363044; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1236	biolink:molecularly_interacts_with	UniProtKB:P01008	RO:0002436	drug_central	Catalyses the inactivation of coagulation proteases by activated antithrombin-III	biolink:Association
DrugCentral:1238	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central		biolink:Association
DrugCentral:1239	biolink:molecularly_interacts_with	UniProtKB:P07900	RO:0002436	drug_central		biolink:Association
DrugCentral:1239	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nM	biolink:Association
DrugCentral:1239	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Displacement of [3H]CGP12177 from human beta-1 adrenoceptor	biolink:Association
DrugCentral:1239	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	Agonist activity at human recombinant beta3 receptor assessed as cAMP accumulation by radioimmunoassay and cell based assay	biolink:Association
DrugCentral:1239	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1245	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Inhibitory activity against angiotensin I converting enzyme (ACE)	biolink:Association
DrugCentral:1247	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1251	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central	In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor	biolink:Association
DrugCentral:1251	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central	In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor	biolink:Association
DrugCentral:1251	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptor	biolink:Association
DrugCentral:1255	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central		biolink:Association
DrugCentral:1255	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:1255	biolink:molecularly_interacts_with	UniProtKB:Q99527	RO:0002436	drug_central		biolink:Association
DrugCentral:1255	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central	Agonist activity at PXR (unknown origin) expressed in human HepG2 cells assessed as induction of CYP3A4 transactivation after 16 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:1255	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assay	biolink:Association
DrugCentral:1255	biolink:molecularly_interacts_with	UniProtKB:P34913	RO:0002436	drug_central	Competitive inhibition of human recombinant soluble epoxide hydrolase using [3H]-tDPPO as substrate	biolink:Association
DrugCentral:1255	biolink:molecularly_interacts_with	UniProtKB:P11474	RO:0002436	drug_central	Antagonist activity at ERalpha receptor in human MCF7 cells assessed as inhibition of cell growth after 6 days by crystal violet staining method	biolink:Association
DrugCentral:1255	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1256	biolink:molecularly_interacts_with	UniProtKB:P45984	RO:0002436	drug_central	Inhibition of human JNK2alpha2 using GST-c-jun (1 to 221) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 mins by liquid scintillation counting	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:Q13621	RO:0002436	drug_central		biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human recombinant full length CA2 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human recombinant full length CA4 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:P28845	RO:0002436	drug_central	Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in presence of NADPH	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:Q9HC97	RO:0002436	drug_central	Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysis	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant full length CA5A by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant full length CA14 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant full length CA7 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human recombinant full length CA1 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant full length CA5B by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human recombinant full length CA6 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central		biolink:Association
DrugCentral:1258	biolink:molecularly_interacts_with	UniProtKB:P55011	RO:0002436	drug_central		biolink:Association
DrugCentral:1261	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:1262	biolink:molecularly_interacts_with	UniProtKB:P24046	RO:0002436	drug_central	Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assay	biolink:Association
DrugCentral:1262	biolink:molecularly_interacts_with	UniProtKB:P30531	RO:0002436	drug_central	Inhibitory activity against human GABA transporter-1 (hGAT1)	biolink:Association
DrugCentral:1262	biolink:molecularly_interacts_with	UniProtKB:P48066	RO:0002436	drug_central	Inhibitory activity against human sodium and chloride dependent GABA transporter 3	biolink:Association
DrugCentral:1262	biolink:molecularly_interacts_with	UniProtKB:P48065	RO:0002436	drug_central	Inhibition of human GABA transporter (hBGT-1) activity.	biolink:Association
DrugCentral:1264	biolink:molecularly_interacts_with	UniProtKB:P54289	RO:0002436	drug_central		biolink:Association
DrugCentral:1264	biolink:molecularly_interacts_with	UniProtKB:Q01650	RO:0002436	drug_central		biolink:Association
DrugCentral:1264	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:1264	biolink:molecularly_interacts_with	UniProtKB:O75899	RO:0002436	drug_central		biolink:Association
DrugCentral:1264	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central		biolink:Association
DrugCentral:1264	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1264	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1264	biolink:molecularly_interacts_with	UniProtKB:Q9NY47	RO:0002436	drug_central		biolink:Association
DrugCentral:1272	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human recombinant AChE using acetylthiocholine as substrate	biolink:Association
DrugCentral:1272	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central	Inhibition of human recombinant BChE using acetylthiocholine as substrate	biolink:Association
DrugCentral:1273	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1273	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Competitive inhibition of EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 4 hrs by FRET assay in presence of para-LRB-AC42	biolink:Association
DrugCentral:1273	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human AChE	biolink:Association
DrugCentral:1273	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:1275	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1275	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1275	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1276	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay	biolink:Association
DrugCentral:1276	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central	Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay	biolink:Association
DrugCentral:1276	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Inhibition of PPAR-alpha (unknown origin) by SPA assay	biolink:Association
DrugCentral:1276	biolink:molecularly_interacts_with	UniProtKB:P13726	RO:0002436	drug_central	Inhibition of amidolytic activity of human tissue factor/human factor 7a	biolink:Association
DrugCentral:1276	biolink:molecularly_interacts_with	UniProtKB:P31213	RO:0002436	drug_central		biolink:Association
DrugCentral:1277	biolink:molecularly_interacts_with	UniProtKB:P41594	RO:0002436	drug_central		biolink:Association
DrugCentral:1277	biolink:molecularly_interacts_with	UniProtKB:Q13255	RO:0002436	drug_central		biolink:Association
DrugCentral:1279	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central	Mechanism of Action; CHEMBL1855; SINGLE PROTEIN	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central		biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Average Binding Constant for JNK3; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(Q252H)-phosphorylated kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(D835Y) kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Inhibition of EGFR	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P45984	RO:0002436	drug_central	Average Binding Constant for JNK2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of recombinant VEGFR2 by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET(Y1235D) kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P49674	RO:0002436	drug_central	Binding constant for full-length CSNK1E	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Binding constant for RIPK2 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central	Binding constant for EPHB4 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Average Binding Constant for GAK; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q52WX2	RO:0002436	drug_central	Binding constant for SBK1 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P48730	RO:0002436	drug_central	Binding constant for CSNK1D kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q86V86	RO:0002436	drug_central	Binding constant for PIM3 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q15139	RO:0002436	drug_central	Binding constant for PRKD1 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P21709	RO:0002436	drug_central	Binding constant for EPHA1 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9BUB5	RO:0002436	drug_central	Binding constant for full-length MKNK1	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P29322	RO:0002436	drug_central	Binding constant for EPHA8 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Binding constant for EPHA3 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:O94768	RO:0002436	drug_central	Binding constant for full-length DRAK2	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	Average Binding Constant for ERBB2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P15735	RO:0002436	drug_central	Binding constant for PHKG2 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:O14578	RO:0002436	drug_central	Binding constant for CIT kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding constant for HIPK4 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding constant for MINK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q8TBX8	RO:0002436	drug_central	Binding constant for PIP5K2C kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9NWZ3	RO:0002436	drug_central	Binding constant for IRAK4 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9NRP7	RO:0002436	drug_central	Binding constant for STK36 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(A829P) kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central	Binding constant for ERBB4 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9UEE5	RO:0002436	drug_central	Binding constant for DRAK1 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Binding constant for EPHA6 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:O75676	RO:0002436	drug_central	Binding constant for RPS6KA4(Kin.Dom.2-C-terminal) kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9HBH9	RO:0002436	drug_central	Average Binding Constant for MKNK2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P54756	RO:0002436	drug_central	Binding constant for EPHA5 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q16816	RO:0002436	drug_central	Binding constant for full-length PHKG1	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central	Binding constant for EPHB1 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9Y616	RO:0002436	drug_central	Binding constant for IRAK3 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding constant for MAP3K2 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P21860	RO:0002436	drug_central	Binding constant for ERBB3 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for full-length SNF1LK2	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P50613	RO:0002436	drug_central	Binding constant for CDK7 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P31152	RO:0002436	drug_central	Binding constant for ERK4 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q16659	RO:0002436	drug_central	Binding constant for ERK3 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:O43293	RO:0002436	drug_central	Binding constant for DAPK3 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9C098	RO:0002436	drug_central	Binding constant for DCAMKL3 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Inhibition of recombinant Ret by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q09013	RO:0002436	drug_central	Binding constant for DMPK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9H1R3	RO:0002436	drug_central	Binding constant for MYLK2 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central	Binding constant for LTK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central	Inhibition of BCRP expressed in MCF7 MX cells by Hoechst 33342 staining	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding constant for MAP3K3 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:O96017	RO:0002436	drug_central	Binding constant for CHEK2 kinase domain	biolink:Association
DrugCentral:1282	biolink:molecularly_interacts_with	UniProtKB:Q9UBE8	RO:0002436	drug_central	Binding constant for NLK kinase domain	biolink:Association
DrugCentral:1283	biolink:molecularly_interacts_with	UniProtKB:P30085	RO:0002436	drug_central		biolink:Association
DrugCentral:1283	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central		biolink:Association
DrugCentral:1283	biolink:molecularly_interacts_with	UniProtKB:P09884	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363042; PROTEIN FAMILY	biolink:Association
DrugCentral:1283	biolink:molecularly_interacts_with	UniProtKB:P28340	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363042; PROTEIN FAMILY	biolink:Association
DrugCentral:1283	biolink:molecularly_interacts_with	UniProtKB:Q07864	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363042; PROTEIN FAMILY	biolink:Association
DrugCentral:1283	biolink:molecularly_interacts_with	UniProtKB:P31350	RO:0002436	drug_central		biolink:Association
DrugCentral:1283	biolink:molecularly_interacts_with	UniProtKB:P23921	RO:0002436	drug_central		biolink:Association
DrugCentral:1283	biolink:molecularly_interacts_with	UniProtKB:P27707	RO:0002436	drug_central		biolink:Association
DrugCentral:1285	biolink:molecularly_interacts_with	UniProtKB:P10632	RO:0002436	drug_central		biolink:Association
DrugCentral:1285	biolink:molecularly_interacts_with	UniProtKB:P06858	RO:0002436	drug_central		biolink:Association
DrugCentral:1285	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central		biolink:Association
DrugCentral:1285	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:1285	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:1291	biolink:molecularly_interacts_with	UniProtKB:P20815	RO:0002436	drug_central		biolink:Association
DrugCentral:1291	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1292	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1293	biolink:molecularly_interacts_with	UniProtKB:Q12882	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1297	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:1298	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1298	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1298	biolink:molecularly_interacts_with	UniProtKB:O60706	RO:0002436	drug_central		biolink:Association
DrugCentral:1298	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:1299	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1299	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1299	biolink:molecularly_interacts_with	UniProtKB:O60706	RO:0002436	drug_central		biolink:Association
DrugCentral:1299	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:1300	biolink:molecularly_interacts_with	UniProtKB:O60706	RO:0002436	drug_central		biolink:Association
DrugCentral:1300	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:1300	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central		biolink:Association
DrugCentral:1300	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:1301	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1301	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1302	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1302	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1305	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1305	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:O00222	RO:0002436	drug_central		biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:Q14832	RO:0002436	drug_central		biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P49448	RO:0002436	drug_central		biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P00367	RO:0002436	drug_central		biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:Q16099	RO:0002436	drug_central		biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P42263	RO:0002436	drug_central		biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:Q14831	RO:0002436	drug_central	Agonist activity at human mGlu7 receptor expressed in HEK293 assessed as inhibition of forskolin stimulated cAMP production	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P43005	RO:0002436	drug_central	Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:Q13255	RO:0002436	drug_central	Displacement of [3H]quisqualate from mGluR1 receptor expressed in BHK cells	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:Q14416	RO:0002436	drug_central	Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P41594	RO:0002436	drug_central	Binding affinity to mGluR5 receptor expressed in BHK cells	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P39086	RO:0002436	drug_central	Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]kainate as radioligand	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:Q16478	RO:0002436	drug_central	Displacement of [3H]kainate from human Ionotropic glutamate receptor ionotropic kainate 1 expressed in HEK293 cells	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:Q13003	RO:0002436	drug_central	Ability to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluated	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P48058	RO:0002436	drug_central	Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 4 in HEK293 cells using [3H]AMPA as radioligand	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P42262	RO:0002436	drug_central	Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 2 in HK293 cells using [3H]AMPA as radioligand	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:Q13002	RO:0002436	drug_central	Binding affinity against human GluR6	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P42261	RO:0002436	drug_central	Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 1 in HEK293 cells using [3H]-AMPA as radioligand	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:Q14833	RO:0002436	drug_central	Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cells	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:O15303	RO:0002436	drug_central	Compound was tested for the inhibition of Metabotropic glutamate receptor 6	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P43003	RO:0002436	drug_central	Inhibition of [3H]D-Asp uptake at EAAT1 in HEK293 cells	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P00390	RO:0002436	drug_central	Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis	biolink:Association
DrugCentral:1310	biolink:molecularly_interacts_with	UniProtKB:P43004	RO:0002436	drug_central	Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cells	biolink:Association
DrugCentral:1312	biolink:molecularly_interacts_with	UniProtKB:Q9Y2Q3	RO:0002436	drug_central	Affinity towards recombinant Glutathione S-transferase (GST) Enzyme.	biolink:Association
DrugCentral:1313	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1313	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1313	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1314	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1314	biolink:molecularly_interacts_with	UniProtKB:P13569	RO:0002436	drug_central		biolink:Association
DrugCentral:1314	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1314	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:1314	biolink:molecularly_interacts_with	UniProtKB:O60706	RO:0002436	drug_central		biolink:Association
DrugCentral:1314	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:1314	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG potassium channel	biolink:Association
DrugCentral:1314	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:1319	biolink:molecularly_interacts_with	UniProtKB:P48067	RO:0002436	drug_central	Inhibition of GlyT1 (unknown origin) assessed as inhibition of [14C]glycine uptake	biolink:Association
DrugCentral:1325	biolink:molecularly_interacts_with	UniProtKB:P28845	RO:0002436	drug_central	Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assay	biolink:Association
DrugCentral:1325	biolink:molecularly_interacts_with	UniProtKB:P80365	RO:0002436	drug_central	Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assay	biolink:Association
DrugCentral:1327	biolink:molecularly_interacts_with	UniProtKB:P22888	RO:0002436	drug_central		biolink:Association
DrugCentral:1327	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central	Mechanism of Action; CHEMBL1855; SINGLE PROTEIN	biolink:Association
DrugCentral:1328	biolink:molecularly_interacts_with	UniProtKB:Q07817	RO:0002436	drug_central	Displacement of FAM-Bak from human Bcl-xL by FP assay	biolink:Association
DrugCentral:1328	biolink:molecularly_interacts_with	UniProtKB:P52732	RO:0002436	drug_central	Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysis	biolink:Association
DrugCentral:1328	biolink:molecularly_interacts_with	UniProtKB:P10415	RO:0002436	drug_central	Displacement of FAM-Bim peptide from human Bcl2 by fluorescence polarization assay	biolink:Association
DrugCentral:1328	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central	The compound was tested for inhibitory activity against Aldose reductase from human placenta	biolink:Association
DrugCentral:1328	biolink:molecularly_interacts_with	UniProtKB:Q92843	RO:0002436	drug_central	Displacement of Flu-Bak peptide from recombinant antiapoptotic Bcl-w protein by fluorescence polarization assay	biolink:Association
DrugCentral:1328	biolink:molecularly_interacts_with	UniProtKB:Q07820	RO:0002436	drug_central	Displacement of FAM-Bid from human Mcl1 by FP assay	biolink:Association
DrugCentral:1328	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Estrogen Receptor-alpha Coactivator Binding Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 629 (Primary screen preceding this dose response confirmation assay.)]	biolink:Association
DrugCentral:1328	biolink:molecularly_interacts_with	UniProtKB:P29372	RO:0002436	drug_central		biolink:Association
DrugCentral:1329	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:1329	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determined	biolink:Association
DrugCentral:1329	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central	In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determined	biolink:Association
DrugCentral:1329	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1329	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central	In vitro Binding affinity towards alpha-3 (PC12) nAChR was determined	biolink:Association
DrugCentral:1329	biolink:molecularly_interacts_with	UniProtKB:O95264	RO:0002436	drug_central	GRAC: human 5-HT3B selective antagonist	biolink:Association
DrugCentral:1329	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1329	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1330	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory activity against Potassium channel HERG	biolink:Association
DrugCentral:1331	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay	biolink:Association
DrugCentral:1334	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human erythrocyte CA1 esterase activity using 4-nitrophenyl acetate substrate	biolink:Association
DrugCentral:1334	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human erythrocyte CA2 esterase activity using 4-nitrophenyl acetate substrate	biolink:Association
DrugCentral:1339	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1339	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1342	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1342	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1342	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:1342	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1342	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1342	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1342	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1343	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1343	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1343	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1343	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1343	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1343	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central	Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2AR	biolink:Association
DrugCentral:1343	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1343	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:O43525	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:O43526	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:O95259	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:P16389	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:P17658	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:P22001	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:P22459	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:P48547	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:P51787	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:P56696	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q03721	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q09470	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q14003	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q14721	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q16322	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q6PIU1	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q8NCM2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q8TAE7	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q8TDN1	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q8TDN2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q92953	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q96KK3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q96L42	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q96PR1	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q96RP8	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9BQ31	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9H252	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9H3M0	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9NR82	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9NS40	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9NSA2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9NZV8	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9UIX4	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9UJ96	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9UK17	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9ULD8	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9ULS6	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1344	biolink:molecularly_interacts_with	UniProtKB:Q9UQ05	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1348	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1349	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:1350	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG expressed in CHO cells	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:O95259	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P0DP23	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P0DP24	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P0DP25	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity for 5-hydroxytryptamine 1A receptor determined using [3H]8-OH-DPAT as radioligand	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Binding affinity to human cloned muscarinic M1 receptor	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Binding affinity to human cloned 5HT6 receptor	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Binding affinity to human cloned 5HT2C receptor	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Binding affinity to human cloned histamine H1 receptor	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Binding affinity to human SERT	biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1353	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	radioligand [3H]spiperone 0.5nM competition binding; human recombinant dopaminereceptors in CHO cells	biolink:Association
DrugCentral:1354	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:1355	biolink:molecularly_interacts_with	UniProtKB:Q14376	RO:0002436	drug_central	Inhibition of human GalE by HPAEC assay	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363052; PROTEIN COMPLEX	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P48167	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363052; PROTEIN COMPLEX	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:P57789	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331041; SINGLE PROTEIN	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:Q7Z418	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331042; SINGLE PROTEIN	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:O14649	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321613; SINGLE PROTEIN	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:Q9NPC2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321614; SINGLE PROTEIN	biolink:Association
DrugCentral:1356	biolink:molecularly_interacts_with	UniProtKB:O95069	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321615; SINGLE PROTEIN	biolink:Association
DrugCentral:1358	biolink:molecularly_interacts_with	UniProtKB:P01008	RO:0002436	drug_central	Catalyses the inactivation of coagulation proteases by activatted antithrombin-III	biolink:Association
DrugCentral:1362	biolink:molecularly_interacts_with	UniProtKB:Q16678	RO:0002436	drug_central	Inhibition of human CYP1B1 by EROD assay	biolink:Association
DrugCentral:1362	biolink:molecularly_interacts_with	UniProtKB:P49841	RO:0002436	drug_central	Inhibition of Homo sapiens (human) recombinant GSK3beta after 30 min by Kinase-Glo assay	biolink:Association
DrugCentral:1362	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central		biolink:Association
DrugCentral:1362	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central		biolink:Association
DrugCentral:1362	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central		biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Estrogen Receptor-beta Coactivator Binding Inhibitors ELISA Secondary Assay. (Class of assay: confirmatory) [Related pubchem assays: 633 (Primary screen preceding this ELISA dose response confirmation assay.), 733 (Primary dose response assay preceding this ELISA dose response confirmation assay.)]	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Estrogen Receptor-alpha Coactivator Binding Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 629 (Primary screen preceding this dose response confirmation assay.)]	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P55072	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase. (Class of assay: confirmatory) [Related pubchem assays: 1481, 1517 ]	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P11142	RO:0002436	drug_central	PUBCHEM_BIOASSAY: High Throughput Screening Assay for Hsc70 Inhibitors. (Class of assay: confirmatory) 	biolink:Association
DrugCentral:1364	biolink:molecularly_interacts_with	UniProtKB:P0DMV8	RO:0002436	drug_central		biolink:Association
DrugCentral:1365	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Mechanism of Action; CHEMBL220; SINGLE PROTEIN	biolink:Association
DrugCentral:1366	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:1366	biolink:molecularly_interacts_with	UniProtKB:Q15825	RO:0002436	drug_central		biolink:Association
DrugCentral:1366	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	GRAC: human AChR-alpha4-beta2 channel blocker	biolink:Association
DrugCentral:1366	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central	GRAC: human AChR-alpha4-beta2 channel blocker	biolink:Association
DrugCentral:1366	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central	GRAC: human AChR-alpha4-beta4 channel blocker	biolink:Association
DrugCentral:1366	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central	GRAC: human AChR-alpha4-beta4 channel blocker	biolink:Association
DrugCentral:1368	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1369	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1370	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1370	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1370	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1371	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1371	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1371	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1371	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1371	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1373	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1373	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1373	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1374	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central	Inhibition of 5-LO in human PMNL using arachidonic acid as substrate preincubated for 15 mins	biolink:Association
DrugCentral:1374	biolink:molecularly_interacts_with	UniProtKB:P14679	RO:0002436	drug_central		biolink:Association
DrugCentral:1375	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	Displacement of [125I]iodoaminopotentidine from human histamine H2 receptor expressed in CHO cells	biolink:Association
DrugCentral:1375	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central	Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2	biolink:Association
DrugCentral:1375	biolink:molecularly_interacts_with	UniProtKB:Q9Y5N1	RO:0002436	drug_central	Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation counting	biolink:Association
DrugCentral:1375	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Displacement of [3H]mepyramine from human wild-type histamine H1 receptor expressed in COS-7 cells by liquid scintillation counting	biolink:Association
DrugCentral:1375	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central		biolink:Association
DrugCentral:1379	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1379	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1379	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1379	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1379	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1384	biolink:molecularly_interacts_with	UniProtKB:Q92736	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1384	biolink:molecularly_interacts_with	UniProtKB:Q9UBC3	RO:0002436	drug_central		biolink:Association
DrugCentral:1384	biolink:molecularly_interacts_with	UniProtKB:Q9Y6K1	RO:0002436	drug_central		biolink:Association
DrugCentral:1384	biolink:molecularly_interacts_with	UniProtKB:P26358	RO:0002436	drug_central		biolink:Association
DrugCentral:1384	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:1384	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1385	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central		biolink:Association
DrugCentral:1385	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5	biolink:Association
DrugCentral:1385	biolink:molecularly_interacts_with	UniProtKB:Q12791	RO:0002436	drug_central		biolink:Association
DrugCentral:1385	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central		biolink:Association
DrugCentral:1385	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:1386	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Displacement of [3H]-U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting	biolink:Association
DrugCentral:1386	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation counting	biolink:Association
DrugCentral:1387	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:1388	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:1388	biolink:molecularly_interacts_with	UniProtKB:P35228	RO:0002436	drug_central		biolink:Association
DrugCentral:1388	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:1388	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:1388	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1388	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:1390	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:1392	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central		biolink:Association
DrugCentral:1393	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting	biolink:Association
DrugCentral:1393	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation counting	biolink:Association
DrugCentral:1393	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation counting	biolink:Association
DrugCentral:1394	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central	(S) enantiomer activation of hTAAR1 in RD-HGA16 cells	biolink:Association
DrugCentral:1394	biolink:molecularly_interacts_with	UniProtKB:P56817	RO:0002436	drug_central	Binding affinity to BACE1 by surface plasmon resonance method	biolink:Association
DrugCentral:1395	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1395	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1395	biolink:molecularly_interacts_with	UniProtKB:P69905	RO:0002436	drug_central		biolink:Association
DrugCentral:1395	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1395	biolink:molecularly_interacts_with	UniProtKB:Q9NYK1	RO:0002436	drug_central	Inhibition of hTLR7 R848-induced luciferase reporter gene activation.	biolink:Association
DrugCentral:1395	biolink:molecularly_interacts_with	UniProtKB:Q9NR96	RO:0002436	drug_central	Inhibition of hTLR9 CpG2006-induced luciferase reporter gene activation.	biolink:Association
DrugCentral:1399	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human CA5a	biolink:Association
DrugCentral:1399	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human CA9	biolink:Association
DrugCentral:1399	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human CA2	biolink:Association
DrugCentral:1399	biolink:molecularly_interacts_with	UniProtKB:P31350	RO:0002436	drug_central		biolink:Association
DrugCentral:1399	biolink:molecularly_interacts_with	UniProtKB:P23921	RO:0002436	drug_central		biolink:Association
DrugCentral:1400	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1400	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:1401	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant CA12 after 6 hrs by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1401	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant CA9 after 6 hrs by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1401	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Inhibition of human recombinant MAOB by fluorimetric method	biolink:Association
DrugCentral:1401	biolink:molecularly_interacts_with	UniProtKB:P37058	RO:0002436	drug_central	Inhibition of human 17beta-HSD3 expressed in HeLa cells	biolink:Association
DrugCentral:1401	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central	Inhibition human recombinant aldose reductase 1 by spectrophotometric analysis	biolink:Association
DrugCentral:1402	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1402	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1402	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1402	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1402	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1404	biolink:molecularly_interacts_with	UniProtKB:P14324	RO:0002436	drug_central	Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 mins	biolink:Association
DrugCentral:1404	biolink:molecularly_interacts_with	UniProtKB:O95749	RO:0002436	drug_central	Inhibition of human recombinant geranylgeranyl diphosphate synthase	biolink:Association
DrugCentral:1406	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of human PDE4D	biolink:Association
DrugCentral:1406	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of human PDE4A	biolink:Association
DrugCentral:1406	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Inhibition of human PDE4C	biolink:Association
DrugCentral:1406	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibition of human PDE4B	biolink:Association
DrugCentral:1407	biolink:molecularly_interacts_with	UniProtKB:P78348	RO:0002436	drug_central		biolink:Association
DrugCentral:1407	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central	Inhibition of recombinant human AKR1C3	biolink:Association
DrugCentral:1407	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1407	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1407	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:1407	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central		biolink:Association
DrugCentral:1407	biolink:molecularly_interacts_with	UniProtKB:Q8N695	RO:0002436	drug_central		biolink:Association
DrugCentral:1407	biolink:molecularly_interacts_with	UniProtKB:P10145	RO:0002436	drug_central	Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay	biolink:Association
DrugCentral:1407	biolink:molecularly_interacts_with	UniProtKB:P52895	RO:0002436	drug_central	Inhibition of human recombinant N-terminal His6-tagged AKR1C2 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one as substrate after 1 hr by fluorimetric analysis	biolink:Association
DrugCentral:1412	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human Potassium channel HERG expressed in mammalian cells	biolink:Association
DrugCentral:1413	biolink:molecularly_interacts_with	UniProtKB:O75907	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1414	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central		biolink:Association
DrugCentral:1414	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:1414	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1416	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:1416	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1416	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1416	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1417	biolink:molecularly_interacts_with	UniProtKB:P04183	RO:0002436	drug_central	Binding affinity constant against HSV-1 thymidine kinase	biolink:Association
DrugCentral:1419	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation counting	biolink:Association
DrugCentral:1419	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation counting	biolink:Association
DrugCentral:1419	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Compound was tested for the binding affinity against histamine H1 receptor by using [3H]mepyramine as radioligand	biolink:Association
DrugCentral:1419	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Compound was tested for the binding affinity against sigma receptor by using [3H]-+3PPP as radioligand	biolink:Association
DrugCentral:1419	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:1419	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	Inhibition of NMDA receptor GluN2B subunit (unknown origin)	biolink:Association
DrugCentral:1422	biolink:molecularly_interacts_with	UniProtKB:P43119	RO:0002436	drug_central		biolink:Association
DrugCentral:1422	biolink:molecularly_interacts_with	UniProtKB:Q13258	RO:0002436	drug_central		biolink:Association
DrugCentral:1422	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central		biolink:Association
DrugCentral:1422	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central		biolink:Association
DrugCentral:1422	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central		biolink:Association
DrugCentral:1422	biolink:molecularly_interacts_with	UniProtKB:P21731	RO:0002436	drug_central		biolink:Association
DrugCentral:1422	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:1422	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central		biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central		biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central		biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central		biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P51813	RO:0002436	drug_central		biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central		biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central		biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Binding constant for JNK3 kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:O75751	RO:0002436	drug_central	Inhibition of human OCT3-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(ITD) kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1-non phosphorylated kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(L747-E749del, A750P) kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of P-glycoprotein expressed in A2780/ADR cells by calcein AM assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P45984	RO:0002436	drug_central	Average Binding Constant for JNK2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of VEGFR2 by liquid scintillation counting	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Inhibition of recombinant human c-Src	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Binding constant for PDGFRA kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q9NYL2	RO:0002436	drug_central	Binding constant for ZAK kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q14680	RO:0002436	drug_central	Binding constant for full-length MELK	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P43405	RO:0002436	drug_central	Inhibition of recombinant Syk	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P04049	RO:0002436	drug_central	Binding constant for RAF1 kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P15056	RO:0002436	drug_central	Binding constant for BRAF(V600E) kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P49759	RO:0002436	drug_central	Average Binding Constant for CLK1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P29322	RO:0002436	drug_central	Binding constant for EPHA8 kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Binding constant for PLK4 kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q59H18	RO:0002436	drug_central	Binding constant for full-length TNNI3K	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding constant for HIPK4 kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells up to 500 uM after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated [14]-metformin uptake expressed in polarized MDCK2 cells after 5 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q8TBX8	RO:0002436	drug_central	Binding constant for PIP5K2C kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q9UEE5	RO:0002436	drug_central	Average Binding Constant for STK17A; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q9HAZ1	RO:0002436	drug_central	Binding constant for CLK4 kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Binding constant for TYK2(JH2domain-pseudokinase) kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q15046	RO:0002436	drug_central	Inhibition of SYK	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding affinity to human active site of N-terminal hexahistidine-tagged ABL2 expressed in Trichoplusia ni infected Sf9 cells by isothermal titration calorimetric assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P45983	RO:0002436	drug_central	Average Binding Constant for JNK1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Inhibition of Abl tyrosine kinase	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Inhibition of Abl tyrosine kinase	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central	Binding constant for DDR2 kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P16083	RO:0002436	drug_central	Competitive inhibition of human recombinant NQO2-mediated mitomycin C metabolism using NADH as cosubstrate incubated for 5 mins prior to NADH addition measured after 30 mins by Michaelis-Menten plot analysis	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central	Inhibition of BCRP expressed in MDCK cells by pheophorbide A assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Inhibition of Bcr-Abl	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P11274	RO:0002436	drug_central	Inhibition of Bcr-Abl	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q9BWU1	RO:0002436	drug_central	Binding constant for CDK11 kinase domain	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Inhibition of the platelet-derived growth factor receptor.	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Inhibition of the platelet-derived growth factor receptor.	biolink:Association
DrugCentral:1423	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	Inhibition of p38alpha	biolink:Association
DrugCentral:1424	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Inhibitory activity on Angiotensin I converting enzyme (ACE) obtained from pig renal cortex and hippuryl-histidyl-leucine as substrate	biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:O95259	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P04156	RO:0002436	drug_central	Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cells	biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1427	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:1429	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1429	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1429	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1429	biolink:molecularly_interacts_with	UniProtKB:Q9NYK1	RO:0002436	drug_central	Agonist activity at human TLR-7 expressed in HEK293 cells after 24 hrs by SEAP reporter gene assay	biolink:Association
DrugCentral:1431	biolink:molecularly_interacts_with	UniProtKB:P14324	RO:0002436	drug_central	inhibition of human recombinant FPP synthase	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central		biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:P51787	RO:0002436	drug_central		biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Binding affinity to human recombinant carbonic anhydrase 2 by isothermal titration calorimetry assay	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human recombinant full length CA4 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Binding affinity to human recombinant carbonic anhydrase 13 by thermal shift assay	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant full length CA5A by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant full length CA14 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant full length CA7 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Binding affinity to human recombinant carbonic anhydrase 1 by thermal shift assay	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant full length CA5B by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:1433	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Binding affinity to human recombinant carbonic anhydrase 6 expressed in Escherichia coli Rosetta2 (DE3) by thermal shift assay	biolink:Association
DrugCentral:1434	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1436	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1436	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1437	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:1437	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:1437	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:1437	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells up to 500 uM after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1437	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated [14]-metformin uptake expressed in HEK293 cells after 1.5 mins by scintillation counting analysis	biolink:Association
DrugCentral:1438	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:1439	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1439	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central		biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central		biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y4	RO:0002436	drug_central		biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central	Inhibition of human recombinant AKR1C3-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphthol	biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P10145	RO:0002436	drug_central	Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay	biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:O14684	RO:0002436	drug_central	Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC analysis	biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P17516	RO:0002436	drug_central	Inhibition of human recombinant GST-tagged AKR1C4 expressed in Escherichia coli using S-tetralol as substrate by fluorometry	biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Agonist activity at androgen receptor (unknown origin) expressed in HeLa cells co-expressing PSA-(ARE)4-Luc13 assessed as induction of DHT-induced luciferase activity after 20 mins by luciferase reporter gene assay	biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central	Inhibition of human MRP1 in human 2008 cells	biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P52895	RO:0002436	drug_central	Inhibition of human recombinant AKR1C2-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphthol	biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:Q9BPW9	RO:0002436	drug_central	Inhibition of 3alphaHSD	biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:Q04760	RO:0002436	drug_central	Inhibition of glyoxalase 1	biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central	In vitro inhibition of rabbit lens aldose reductase.	biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:Q96RP8	RO:0002436	drug_central		biolink:Association
DrugCentral:1440	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1443	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1443	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	The compound was tested for binding affinity against Alpha-2A adrenergic receptor from human clones.	biolink:Association
DrugCentral:1443	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Binding affinity against Alpha-1D adrenergic receptor, from human clones.	biolink:Association
DrugCentral:1443	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	The compound was tested for binding affinity against Alpha-1A adrenergic receptor from human clones.	biolink:Association
DrugCentral:1443	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	The compound was tested for binding affinity against Alpha-1B adrenergic receptor, from hamster clones.	biolink:Association
DrugCentral:1443	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Binding affinity against Alpha-2B adrenergic receptor from human clones.	biolink:Association
DrugCentral:1443	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Binding affinity against Alpha-2C adrenergic receptor from human clones.	biolink:Association
DrugCentral:1446	biolink:molecularly_interacts_with	UniProtKB:Q969P6	RO:0002436	drug_central		biolink:Association
DrugCentral:1446	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central		biolink:Association
DrugCentral:1446	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central		biolink:Association
DrugCentral:1457	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1457	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1457	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1457	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1457	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1457	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1457	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1457	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1475	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1475	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:1475	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1475	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1475	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1475	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1477	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:1477	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1478	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1478	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1478	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1478	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1480	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of human recombinant MAOA	biolink:Association
DrugCentral:1480	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Inhibition of human recombinant MAOB	biolink:Association
DrugCentral:1481	biolink:molecularly_interacts_with	UniProtKB:Q14973	RO:0002436	drug_central		biolink:Association
DrugCentral:1481	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central	Inhibitory concentration against angiotensin II receptor, type 1	biolink:Association
DrugCentral:1481	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central	Binding affinity to ETA receptor	biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central		biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:P03956	RO:0002436	drug_central	DRUGMATRIX: Peptidase, Matrix Metalloproteinase-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:O15439	RO:0002436	drug_central		biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:O75751	RO:0002436	drug_central	Inhibition of human OCT3-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of human OCT1-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human AChE	biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells up to 500 uM after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1482	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated [14]-metformin uptake expressed in HEK293 cells after 1.5 mins by scintillation counting analysis	biolink:Association
DrugCentral:1483	biolink:molecularly_interacts_with	UniProtKB:O96017	RO:0002436	drug_central		biolink:Association
DrugCentral:1490	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central		biolink:Association
DrugCentral:1490	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central		biolink:Association
DrugCentral:1491	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nM	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363052; PROTEIN COMPLEX	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P48167	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363052; PROTEIN COMPLEX	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P57789	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331041; SINGLE PROTEIN	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:Q7Z418	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331042; SINGLE PROTEIN	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:O14649	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321613; SINGLE PROTEIN	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:Q9NPC2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321614; SINGLE PROTEIN	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:O95069	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321615; SINGLE PROTEIN	biolink:Association
DrugCentral:1493	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1494	biolink:molecularly_interacts_with	UniProtKB:P10619	RO:0002436	drug_central	Inhibition of recombinant CatA using [14C]GS-7340 substrate	biolink:Association
DrugCentral:1494	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human AChE assessed as equilibrium binding by modified Ellman's spectrophotometric method	biolink:Association
DrugCentral:1494	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1497	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1497	biolink:molecularly_interacts_with	UniProtKB:P20815	RO:0002436	drug_central		biolink:Association
DrugCentral:1499	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:1499	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1499	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1500	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Mechanism of Action; CHEMBL245; SINGLE PROTEIN	biolink:Association
DrugCentral:1500	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Mechanism of Action; CHEMBL216; SINGLE PROTEIN	biolink:Association
DrugCentral:1505	biolink:molecularly_interacts_with	UniProtKB:O75343	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1505	biolink:molecularly_interacts_with	UniProtKB:P33402	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1505	biolink:molecularly_interacts_with	UniProtKB:Q02108	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1505	biolink:molecularly_interacts_with	UniProtKB:Q02153	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1505	biolink:molecularly_interacts_with	UniProtKB:P16066	RO:0002436	drug_central		biolink:Association
DrugCentral:1506	biolink:molecularly_interacts_with	UniProtKB:O75343	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1506	biolink:molecularly_interacts_with	UniProtKB:P33402	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1506	biolink:molecularly_interacts_with	UniProtKB:Q02108	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1506	biolink:molecularly_interacts_with	UniProtKB:Q02153	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1506	biolink:molecularly_interacts_with	UniProtKB:P16066	RO:0002436	drug_central		biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:P10826	RO:0002436	drug_central	Mechanism of Action; CHEMBL2008; SINGLE PROTEIN	biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:O14756	RO:0002436	drug_central		biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:Q92781	RO:0002436	drug_central		biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:Q9BPW9	RO:0002436	drug_central		biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:P08319	RO:0002436	drug_central		biolink:Association
DrugCentral:1508	biolink:molecularly_interacts_with	UniProtKB:P10276	RO:0002436	drug_central		biolink:Association
DrugCentral:1509	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1509	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1511	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Recombinant Ca<sub>v</sub>1.3 calcium channel complexes expressed in tsA201-cells	biolink:Association
DrugCentral:1511	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:1511	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:1511	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:1511	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1513	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:1513	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1513	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central	Inhibition of vasopressin-stimulated vasopressin V2 receptor in human HTLA cells pre-incubated for 20 mins measured on day 4 by beta arrestin-recruitment mediated luciferase reporter gene assay	biolink:Association
DrugCentral:1513	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay	biolink:Association
DrugCentral:1513	biolink:molecularly_interacts_with	UniProtKB:P51679	RO:0002436	drug_central	Inverse agonist activity at CCR4 in human HTLA cells assessed as depression of basal activity incubated for 20 mins by beta arrestin-recruitment mediated luciferase reporter gene assay in absence of CCL22	biolink:Association
DrugCentral:1513	biolink:molecularly_interacts_with	UniProtKB:P25024	RO:0002436	drug_central	Inhibition of CX3CL1-stimulated CX3CR1 in human HTLA cells pre-incubated for 20 mins measured on day 4 by beta arrestin-recruitment mediated luciferase reporter gene assay	biolink:Association
DrugCentral:1513	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cells	biolink:Association
DrugCentral:1517	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1517	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1517	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1517	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1517	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1517	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1517	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1517	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1517	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:O60391	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:P42261	RO:0002436	drug_central	antidepressant action of (2R,6R)-HNK metabolite	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:P42262	RO:0002436	drug_central	antidepressant action of (2R,6R)-HNK metabolite	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:P42263	RO:0002436	drug_central	antidepressant action of (2R,6R)-HNK metabolite	biolink:Association
DrugCentral:1523	biolink:molecularly_interacts_with	UniProtKB:P48058	RO:0002436	drug_central	antidepressant action of (2R,6R)-HNK metabolite	biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:Q05940	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 6 receptor was evaluated using [3H]-LSD as radioligand	biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity for Dopamine receptor D2 by displacement of [3H]-spiperone	biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding affinity towards human dopamine receptor D4	biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central	Binding affinity to human cloned 5-hydroxytryptamine 1B receptor in CHO cells by [3H]5-HT binding displacement.	biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	GRAC: human 5-HT2A selective antagonist	biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central	Binding affinity by displacement to human cloned 5-hydroxytryptamine 1D receptor in CHO cells by [3H]5-HT displacement.	biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	The compound was tested for affinity towards sigma-3 receptor	biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P54219	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1524	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1526	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:1526	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:1526	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:1526	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:Q16322	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:Q07973	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P05093	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P15538	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P19099	RO:0002436	drug_central		biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorometric assay	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P08686	RO:0002436	drug_central	Inhibition of Progesterone 21-hydroxylase cytochrome P450 21	biolink:Association
DrugCentral:1527	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central		biolink:Association
DrugCentral:1528	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1528	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1529	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1529	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1530	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1531	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:1531	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:1531	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:1531	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1531	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:1531	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1531	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1531	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1531	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1532	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:1532	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1532	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1532	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1532	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1532	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1532	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:1532	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1532	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1535	biolink:molecularly_interacts_with	UniProtKB:O00182	RO:0002436	drug_central	Binding affinity to galectin 9N terminal domain at 0 degC by fluorescence polarization assay	biolink:Association
DrugCentral:1535	biolink:molecularly_interacts_with	UniProtKB:O00214	RO:0002436	drug_central	Binding affinity to galectin 8N terminal domain at 20 degC by fluorescence polarization assay	biolink:Association
DrugCentral:1539	biolink:molecularly_interacts_with	UniProtKB:P27707	RO:0002436	drug_central		biolink:Association
DrugCentral:1540	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Inhibition of human Nav1.7 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assay	biolink:Association
DrugCentral:1540	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central		biolink:Association
DrugCentral:1540	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of human Nav1.3 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assay	biolink:Association
DrugCentral:1540	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:1540	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central	Inhibition of human recombinant Nav1.8 channel expressed in HEK293 cells by whole cell voltage clamp technique	biolink:Association
DrugCentral:1540	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Inhibition of human recombinant Nav1.5 channel expressed in HEK293 cells by whole cell voltage clamp technique	biolink:Association
DrugCentral:1540	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Affinity for inactive human SkM1 sodium channel expressed in HEK293 cells	biolink:Association
DrugCentral:1540	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of human recombinant Nav1.2 channel expressed in HEK293 cells by whole cell voltage clamp technique	biolink:Association
DrugCentral:1540	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:1540	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:1545	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1546	biolink:molecularly_interacts_with	UniProtKB:P31391	RO:0002436	drug_central		biolink:Association
DrugCentral:1546	biolink:molecularly_interacts_with	UniProtKB:P30872	RO:0002436	drug_central		biolink:Association
DrugCentral:1546	biolink:molecularly_interacts_with	UniProtKB:P35346	RO:0002436	drug_central		biolink:Association
DrugCentral:1546	biolink:molecularly_interacts_with	UniProtKB:P30874	RO:0002436	drug_central		biolink:Association
DrugCentral:1546	biolink:molecularly_interacts_with	UniProtKB:P32745	RO:0002436	drug_central		biolink:Association
DrugCentral:1547	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1547	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1547	biolink:molecularly_interacts_with	UniProtKB:P10636	RO:0002436	drug_central	Binding affinity to heparin induced human Tau 441 at 50 pM to 500 nM after 30 mins	biolink:Association
DrugCentral:1547	biolink:molecularly_interacts_with	UniProtKB:P20648	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095173; PROTEIN COMPLEX	biolink:Association
DrugCentral:1547	biolink:molecularly_interacts_with	UniProtKB:P51164	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095173; PROTEIN COMPLEX	biolink:Association
DrugCentral:1547	biolink:molecularly_interacts_with	UniProtKB:Q8TCT1	RO:0002436	drug_central	PUBCHEM_BIOASSAY: SAR assay for compounds that inhibit PHOSPHO1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1545, AID1565, AID1574]	biolink:Association
DrugCentral:1547	biolink:molecularly_interacts_with	UniProtKB:P49327	RO:0002436	drug_central		biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:Q9Y6L6	RO:0002436	drug_central		biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Inhibition of ABL1 by flash plate based radioactive enzyme assay	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(G719C) kinase domain	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:Q9UBF8	RO:0002436	drug_central	Binding constant for PIK4CB kinase domain	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Inhibition of INSR by flash plate based radioactive enzyme assay	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Binding constant for RIPK2 kinase domain	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:O75747	RO:0002436	drug_central	Binding constant for PIK3C2G kinase domain	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Average Binding Constant for STK10; NA=Not Active at 10 uM	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	Binding constant for ERBB2 kinase domain	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Inhibition of PDGFRbeta by flash plate based radioactive enzyme assay	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:O00750	RO:0002436	drug_central	Binding constant for PIK3C2B kinase domain	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central	Binding constant for ERBB4 kinase domain	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:P24941	RO:0002436	drug_central	Inhibition of CDK2 by flash plate based radioactive enzyme assay	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:O14733	RO:0002436	drug_central	Binding constant for MKK7 kinase domain	biolink:Association
DrugCentral:1548	biolink:molecularly_interacts_with	UniProtKB:P21860	RO:0002436	drug_central	Binding constant for ERBB3 kinase domain	biolink:Association
DrugCentral:1549	biolink:molecularly_interacts_with	UniProtKB:P35228	RO:0002436	drug_central	Binding affinity to truncated iNOS construct (1-490) by spectral assay	biolink:Association
DrugCentral:1550	biolink:molecularly_interacts_with	UniProtKB:P14868	RO:0002436	drug_central		biolink:Association
DrugCentral:1550	biolink:molecularly_interacts_with	UniProtKB:Q12797	RO:0002436	drug_central		biolink:Association
DrugCentral:1550	biolink:molecularly_interacts_with	UniProtKB:P00505	RO:0002436	drug_central		biolink:Association
DrugCentral:1550	biolink:molecularly_interacts_with	UniProtKB:Q03154	RO:0002436	drug_central		biolink:Association
DrugCentral:1550	biolink:molecularly_interacts_with	UniProtKB:P00966	RO:0002436	drug_central		biolink:Association
DrugCentral:1550	biolink:molecularly_interacts_with	UniProtKB:P08243	RO:0002436	drug_central		biolink:Association
DrugCentral:1550	biolink:molecularly_interacts_with	UniProtKB:P45381	RO:0002436	drug_central		biolink:Association
DrugCentral:1550	biolink:molecularly_interacts_with	UniProtKB:P17174	RO:0002436	drug_central		biolink:Association
DrugCentral:1550	biolink:molecularly_interacts_with	UniProtKB:O75746	RO:0002436	drug_central		biolink:Association
DrugCentral:1550	biolink:molecularly_interacts_with	UniProtKB:Q9UJS0	RO:0002436	drug_central		biolink:Association
DrugCentral:1551	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central		biolink:Association
DrugCentral:1551	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:1551	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:1552	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1552	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1552	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1552	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:1552	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:1552	biolink:molecularly_interacts_with	UniProtKB:Q02127	RO:0002436	drug_central	Immunosuppressive activity expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)	biolink:Association
DrugCentral:1556	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central		biolink:Association
DrugCentral:1556	biolink:molecularly_interacts_with	UniProtKB:P15538	RO:0002436	drug_central	Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxy-corticosterone as substrate	biolink:Association
DrugCentral:1556	biolink:molecularly_interacts_with	UniProtKB:P19099	RO:0002436	drug_central	Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxy-corticosterone as substrate	biolink:Association
DrugCentral:1559	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central		biolink:Association
DrugCentral:1560	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Displacement of [125I]-IBOxyA from MOR-1 expressed in CHO cells	biolink:Association
DrugCentral:1561	biolink:molecularly_interacts_with	UniProtKB:P05186	RO:0002436	drug_central	Inhibition of TNSALP	biolink:Association
DrugCentral:1562	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central	Activation of human TAAR1 expressed in human HEK293T cells assessed as cAMP accumulation after 10 mins by BRET assay	biolink:Association
DrugCentral:1562	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity towards sigma opioid receptor in guinea pig cerebral homogenate using [3H]DTG as radioligand	biolink:Association
DrugCentral:1563	biolink:molecularly_interacts_with	UniProtKB:Q7L0J3	RO:0002436	drug_central	Mechanism of Action; CHEMBL1998; SINGLE PROTEIN	biolink:Association
DrugCentral:1563	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central		biolink:Association
DrugCentral:1563	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central		biolink:Association
DrugCentral:1563	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:1564	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1564	biolink:molecularly_interacts_with	UniProtKB:O95665	RO:0002436	drug_central		biolink:Association
DrugCentral:1564	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1566	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1567	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1567	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1567	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1567	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1567	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1569	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1569	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1569	biolink:molecularly_interacts_with	UniProtKB:Q9Y256	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Human Ras-Converting Enzyme Inhibition Assay Measured in Biochemical System Using Plate Reader - 2034-04_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2618]	biolink:Association
DrugCentral:1571	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1571	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1572	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1572	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1572	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1572	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1572	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Inhibition of [3H]U-69593 binding to Opioid receptor kappa 1 of Chinese hamster ovary membrane	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Inhibition of [3H]naltrindole binding to opioid receptor delta 1 of Chinese hamster ovary membrane	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of Chinese hamster ovary membrane	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central	Binding affinity against dextromethorpin binding site associated with N-methyl-D-aspartate glutamate receptor from guinea pig mitochondriall pellet P2 determined using [3H]1 as radioligand.	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:O60391	RO:0002436	drug_central	Binding affinity against dextromethorpin binding site associated with N-methyl-D-aspartate glutamate receptor from guinea pig mitochondriall pellet P2 determined using [3H]1 as radioligand.	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Binding affinity against dextromethorpin binding site associated with N-methyl-D-aspartate glutamate receptor from guinea pig mitochondriall pellet P2 determined using [3H]1 as radioligand.	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	Binding affinity against dextromethorpin binding site associated with N-methyl-D-aspartate glutamate receptor from guinea pig mitochondriall pellet P2 determined using [3H]1 as radioligand.	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	Binding affinity against dextromethorpin binding site associated with N-methyl-D-aspartate glutamate receptor from guinea pig mitochondriall pellet P2 determined using [3H]1 as radioligand.	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central	Binding affinity against dextromethorpin binding site associated with N-methyl-D-aspartate glutamate receptor from guinea pig mitochondriall pellet P2 determined using [3H]1 as radioligand.	biolink:Association
DrugCentral:1574	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central	Binding affinity against dextromethorpin binding site associated with N-methyl-D-aspartate glutamate receptor from guinea pig mitochondriall pellet P2 determined using [3H]1 as radioligand.	biolink:Association
DrugCentral:1575	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cells in presence of 100 uM boric acid	biolink:Association
DrugCentral:1576	biolink:molecularly_interacts_with	UniProtKB:Q15842	RO:0002436	drug_central		biolink:Association
DrugCentral:1576	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:1576	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central		biolink:Association
DrugCentral:1576	biolink:molecularly_interacts_with	UniProtKB:P63316	RO:0002436	drug_central	affinity for the binding of levosimendan to cNTnC-Ca2+-cTnI-(144-163) complex	biolink:Association
DrugCentral:1577	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	In vitro displacement of [3H]spiperone from the recombinant human dopamine receptor D2 short form expressed in CHO cells	biolink:Association
DrugCentral:1577	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	In vitro displacement of [3H]spiperone from the recombinant human dopamine receptor D4 expressed in CHO cells	biolink:Association
DrugCentral:1577	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	In vitro displacement of [3H]spiperone from the cloned human dopamine receptor D3 stably expressed in CHO cells	biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central		biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central		biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Modulation of human Nav1.4 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiology	biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Modulation of human Nav1.7 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiology	biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Modulation of human Nav1.3 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiology	biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:1579	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:1580	biolink:molecularly_interacts_with	UniProtKB:Q99808	RO:0002436	drug_central	Inhibition of ENT1 in human K562 cells by flow cytometric assay	biolink:Association
DrugCentral:1580	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against potassium channel HERG	biolink:Association
DrugCentral:1581	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA beta3 receptor	biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha1beta3gamma2 receptor	biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha1beta3gamma2 receptor	biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha1beta3gamma2 receptor	biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:P24046	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA rho1 receptor	biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha1beta1gamma2 receptor	biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha1beta1gamma2 receptor	biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha1beta1gamma2 receptor	biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha6beta3gamma2 receptor	biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha6beta3gamma2 receptor	biolink:Association
DrugCentral:1583	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha6beta3gamma2 receptor	biolink:Association
DrugCentral:1584	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central		biolink:Association
DrugCentral:1584	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of MAO-A (unknown origin) by luciferase reporter gene assay	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX)	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:Q9NVV9	RO:0002436	drug_central		biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P12004	RO:0002436	drug_central	Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P10827	RO:0002436	drug_central	Displacement of [125I]T3 from human TRalpha receptor	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Direct channel-gating action blocked by picrotoxin	biolink:Association
DrugCentral:1585	biolink:molecularly_interacts_with	UniProtKB:P10828	RO:0002436	drug_central	Inhibitory activity against [125I]T3 binding to human TRbeta1 receptor	biolink:Association
DrugCentral:1587	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central		biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity towards Serotonin 5-hydroxytryptamine 1A receptor by displacement of [3H]-(+)-8-OH-DPAT.	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity towards Dopamine receptor D2 by displacement of [3H]U-86170.	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Affinity towards Dopamine receptor D1	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Binding affinity towards Dopamine receptor D3 by displacement of [3H](+)-7-OH-DPAT.	biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1588	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1592	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1593	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Displacement of [3H]RS-79948-197 from human adrenoceptor aplha 2B expressed in CHO cells	biolink:Association
DrugCentral:1593	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Displacement of [3H]RS-79948-197 from human adrenoceptor aplha 2C expressed in CHO cells	biolink:Association
DrugCentral:1593	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HeLa cells after 30 mins	biolink:Association
DrugCentral:1593	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Displacement of [3H]RS-79948-197 from human adrenoceptor aplha 2A expressed in CHO cells	biolink:Association
DrugCentral:1595	biolink:molecularly_interacts_with	UniProtKB:Q00975	RO:0002436	drug_central	Inhibition of calcium channel Cav2.2 in IMR32 cells	biolink:Association
DrugCentral:1597	biolink:molecularly_interacts_with	UniProtKB:O14684	RO:0002436	drug_central	Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC analysis	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P35346	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P0DP23	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P0DP24	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P0DP25	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:O00555	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central		biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding affinity to human recombinant Tie2 by SPR assay	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1599	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1601	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of human MDR1-dependent accumulation of calcein-AM expressed in MDCK2 cells	biolink:Association
DrugCentral:1601	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1602	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1605	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1605	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1605	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1605	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1605	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1605	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central	Agonist activity at PXR (unknown origin) expressed in human HepG2 cells assessed as induction of CYP3A4 transactivation after 16 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:1605	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assay	biolink:Association
DrugCentral:1605	biolink:molecularly_interacts_with	UniProtKB:Q9H2J7	RO:0002436	drug_central		biolink:Association
DrugCentral:1606	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1606	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1606	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1607	biolink:molecularly_interacts_with	UniProtKB:Q8IWT1	RO:0002436	drug_central		biolink:Association
DrugCentral:1607	biolink:molecularly_interacts_with	UniProtKB:Q9NY72	RO:0002436	drug_central		biolink:Association
DrugCentral:1607	biolink:molecularly_interacts_with	UniProtKB:O60939	RO:0002436	drug_central		biolink:Association
DrugCentral:1607	biolink:molecularly_interacts_with	UniProtKB:Q07699	RO:0002436	drug_central		biolink:Association
DrugCentral:1607	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibitory effect in cAMP-specific Phosphodiesterase 4 (PDE 4) isolated from guinea pig ventricular tissue.	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibitory effect in cAMP-specific Phosphodiesterase 4 (PDE 4) isolated from guinea pig ventricular tissue.	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Inhibitory effect in cAMP-specific Phosphodiesterase 4 (PDE 4) isolated from guinea pig ventricular tissue.	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibitory effect in cAMP-specific Phosphodiesterase 4 (PDE 4) isolated from guinea pig ventricular tissue.	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Inhibitory activity against angiotensin I converting enzyme (ACE)	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central	Inhibition of angiotensin AT1 receptor	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:P50052	RO:0002436	drug_central	In vitro binding affinity of compound against angiotensin II AT-2 receptor	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central	Potency to antagonize the ability of angiotensin II to contract rabbit aorta	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:P50052	RO:0002436	drug_central	Potency to antagonize the ability of angiotensin II to contract rabbit aorta	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Inhibition of Phosphodiesterase 3	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Inhibition of Phosphodiesterase 3	biolink:Association
DrugCentral:1610	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1611	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central		biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX)	biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:Q8TDS4	RO:0002436	drug_central		biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:P49019	RO:0002436	drug_central		biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:Q9UBN7	RO:0002436	drug_central	Inhibition of recombinant HDAC6 (unknown origin) after 10 mins by fluorimetric analysis	biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:P20701	RO:0002436	drug_central	Binding affinity to I-domain of human integrin alphaL (amino acid residues 128 to 307) plus initial methionine expressed in Escherichia coli by NMR spectroscopy	biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central	Inhibition of recombinant HDAC1 (unknown origin) after 10 mins by fluorimetric analysis	biolink:Association
DrugCentral:1612	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central	Inhibition of recombinant HDAC2 (unknown origin) after 10 mins by fluorimetric analysis	biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Inhibition of binding of 1.0 nM [3H]pirenzepine to cloned human Muscarinic acetylcholine receptor M1 expressed in membranes from CHO-K1 cells	biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 6 receptor	biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Affinity was evaluated by inhibition of [3H]spiperone binding to COS cells transfected with human dopamine D-2(long) receptor	biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-4 receptor	biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHO cells after 60 mins by liquid scintillation counting	biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Binding affinity towards human Dopamine receptor D3	biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1613	biolink:molecularly_interacts_with	UniProtKB:Q5JUK3	RO:0002436	drug_central		biolink:Association
DrugCentral:1614	biolink:molecularly_interacts_with	UniProtKB:P32238	RO:0002436	drug_central	Displacement of [111In]DTPA-Glu-Gly-[Tyr27(SO3H)]-CCK8 from human CCK1 receptor in A431 cells	biolink:Association
DrugCentral:1615	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibitory potency against Prostaglandin G/H synthase 1 in human whole blood assay	biolink:Association
DrugCentral:1615	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition of COX2 in human whole blood assessed as PGE2 biosynthesis after 24 hrs by EIA	biolink:Association
DrugCentral:1616	biolink:molecularly_interacts_with	UniProtKB:P27695	RO:0002436	drug_central		biolink:Association
DrugCentral:1617	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against IKr potassium channel	biolink:Association
DrugCentral:1618	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX1	biolink:Association
DrugCentral:1618	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition of human COX2 preincubated before addition of [1-14C]arachidonic acid	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity towards Beta-2 adrenergic receptor	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Binding affinity towards Beta-1 adrenergic receptor	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central	Binding affinities towards 5-hydroxytryptamine 5A receptor	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding affinity towards Dopamine receptor D4	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central	Binding affinity towards 5-hydroxytryptamine 1D receptor alpha using [3H]8-OH-DPAT as radioligand	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Binding affinity towards Histamine H1 receptor	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central	Binding affinity towards 5-hydroxytryptamine 1E receptor	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central	Binding affinity towards Dopamine receptor D5	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	GRAC: human 5-HT7 radioligand	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Binding affinity towards 5-hydroxytryptamine 2B receptor using [125I]DOI as radioligand	biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1621	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1622	biolink:molecularly_interacts_with	UniProtKB:P00390	RO:0002436	drug_central	Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis	biolink:Association
DrugCentral:1624	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VA	biolink:Association
DrugCentral:1624	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase II (hCA II) by using esterase assay method	biolink:Association
DrugCentral:1624	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay	biolink:Association
DrugCentral:1624	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Ki value against human carbonic anhydrase VII	biolink:Association
DrugCentral:1624	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibitory constant against catalytic domain of human carbonic anhydrase XII	biolink:Association
DrugCentral:1624	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase IX (hCA IX) by using CO2 hydrase assay method	biolink:Association
DrugCentral:1624	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of cloned isozyme, human carbonic anhydrase IV	biolink:Association
DrugCentral:1624	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assay	biolink:Association
DrugCentral:1624	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VB	biolink:Association
DrugCentral:1624	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of full length human recombinant CA VI	biolink:Association
DrugCentral:1626	biolink:molecularly_interacts_with	UniProtKB:P48039	RO:0002436	drug_central		biolink:Association
DrugCentral:1631	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1631	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1634	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1635	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1635	biolink:molecularly_interacts_with	UniProtKB:P51681	RO:0002436	drug_central	Binding affinity to CCR5	biolink:Association
DrugCentral:1637	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central	Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after 15 mins by enzyme immunoassay	biolink:Association
DrugCentral:1637	biolink:molecularly_interacts_with	UniProtKB:O15296	RO:0002436	drug_central	Inhibition of 15-hLO2	biolink:Association
DrugCentral:1637	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Transcriptional activity at human androgen receptor BF3 site stably transfected in eGFP-expressing human LNCAP cells after 5 days by fluorometric analysis	biolink:Association
DrugCentral:1637	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of human placental microsome CYP19	biolink:Association
DrugCentral:1637	biolink:molecularly_interacts_with	UniProtKB:P18054	RO:0002436	drug_central	Inhibition of human platelet-type 12-lipoxygenase	biolink:Association
DrugCentral:1637	biolink:molecularly_interacts_with	UniProtKB:P16050	RO:0002436	drug_central	Inhibitory activity against human reticulocyte 15-lipoxygenase (15-HLO)	biolink:Association
DrugCentral:1637	biolink:molecularly_interacts_with	UniProtKB:P08069	RO:0002436	drug_central	Inhibition of IGF1R	biolink:Association
DrugCentral:1637	biolink:molecularly_interacts_with	UniProtKB:Q15722	RO:0002436	drug_central	The compound was tested for its inhibitory activity against LTB4 in human PMN	biolink:Association
DrugCentral:1637	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Estrogen Receptor-alpha Coactivator Binding Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 629 (Primary screen preceding this dose response confirmation assay.)]	biolink:Association
DrugCentral:1637	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:1640	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1640	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	The compound was tested for affinity towards sigma-3 receptor	biolink:Association
DrugCentral:1640	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	GRAC: human DAT selective inhibitor	biolink:Association
DrugCentral:1640	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	GRAC: human NET probe	biolink:Association
DrugCentral:1640	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Displacement of [125I]- RTI-55 from Serotonin transporter expressed in HEK cells	biolink:Association
DrugCentral:1641	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Inhibition of human ABL by radiometric assay	biolink:Association
DrugCentral:1641	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of VEGFR2 after 60 mins by electrophoretic mobility shift assay	biolink:Association
DrugCentral:1643	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:1643	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1643	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1643	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:Q15825	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2	biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central	Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2	biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central	Inhibitory concentration against Nicotinic acetylcholine receptor alpha2-beta4	biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central	Inhibitory concentration against Nicotinic acetylcholine receptor alpha2-beta4	biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	GRAC: human AChR-alpha6-alpha3-beta2-beta3 [chimera] commonly used antagonist	biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central	GRAC: human AChR-alpha6-alpha3-beta2-beta3 [chimera] commonly used antagonist	biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:Q05901	RO:0002436	drug_central	GRAC: human AChR-alpha6-alpha3-beta2-beta3 [chimera] commonly used antagonist	biolink:Association
DrugCentral:1646	biolink:molecularly_interacts_with	UniProtKB:Q15825	RO:0002436	drug_central	GRAC: human AChR-alpha6-alpha3-beta2-beta3 [chimera] commonly used antagonist	biolink:Association
DrugCentral:1649	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:1649	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action; CHEMBL231; SINGLE PROTEIN	biolink:Association
DrugCentral:1650	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central		biolink:Association
DrugCentral:1650	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1650	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central	Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one as substrate after 1 hr by fluorimetric analysis	biolink:Association
DrugCentral:1650	biolink:molecularly_interacts_with	UniProtKB:P12104	RO:0002436	drug_central	Displacement of 1-anilinonaphthalene-8-sulphonic acid from I-FABP	biolink:Association
DrugCentral:1650	biolink:molecularly_interacts_with	UniProtKB:P52895	RO:0002436	drug_central	Inhibition of human recombinant N-terminal His6-tagged AKR1C2 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one as substrate after 1 hr by fluorimetric analysis	biolink:Association
DrugCentral:1650	biolink:molecularly_interacts_with	UniProtKB:Q04828	RO:0002436	drug_central	Inhibition of human recombinant N-terminal His6-tagged AKR1C1 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one as substrate after 1 hr by fluorimetric analysis	biolink:Association
DrugCentral:1650	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1650	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1650	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1650	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:1655	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Tested for its inhibitory activity against alpha-2 adrenoceptor in guinea pig ileum	biolink:Association
DrugCentral:1655	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Tested for its inhibitory activity against alpha-2 adrenoceptor in guinea pig ileum	biolink:Association
DrugCentral:1655	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Tested for its inhibitory activity against alpha-2 adrenoceptor in guinea pig ileum	biolink:Association
DrugCentral:1655	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Tested for its inhibitory activity against alpha-1 adrenoceptor in guinea pig ileum	biolink:Association
DrugCentral:1655	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Tested for its inhibitory activity against alpha-1 adrenoceptor in guinea pig ileum	biolink:Association
DrugCentral:1655	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Tested for its inhibitory activity against alpha-1 adrenoceptor in guinea pig ileum	biolink:Association
DrugCentral:1658	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1658	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central	Inhibition of recombinant AKR1C3 (unknown origin) assessed as decrease in oxidation of 1-acenaphthenol substrate by spectrophotometric analysis	biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Inhibition of Dexamethasone binding to human glucocorticoid receptor expressed in baculovirus SF-12 cells	biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:Q04828	RO:0002436	drug_central	Inhibition of human recombinant AKR1C1 expressed in Escherichia coli assessed as decrease in oxidation of 1-acenaphthenol substrate by spectrophotometric analysis	biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central	Inhibitory activity against human Mineralocorticoid receptor	biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Inhibition of binding to human estrogen receptor	biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Inhibition of binding to human estrogen receptor	biolink:Association
DrugCentral:1659	biolink:molecularly_interacts_with	UniProtKB:P52895	RO:0002436	drug_central	Inhibition of recombinant AKR1C2 (unknown origin) assessed as decrease in oxidation of 1-acenaphthenol substrate by spectrophotometric analysis	biolink:Association
DrugCentral:1662	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:1663	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central	Inhibition of human recombinant AKR1C3 assessed as 1-acenaphthenol oxidation by spectrophotometry	biolink:Association
DrugCentral:1663	biolink:molecularly_interacts_with	UniProtKB:P52895	RO:0002436	drug_central	Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometry	biolink:Association
DrugCentral:1663	biolink:molecularly_interacts_with	UniProtKB:Q04828	RO:0002436	drug_central	Inhibition of human recombinant AKR1C1 assessed as 1-acenaphthenol oxidation by spectrophotometry	biolink:Association
DrugCentral:1663	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1663	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1663	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:1663	biolink:molecularly_interacts_with	UniProtKB:O60218	RO:0002436	drug_central		biolink:Association
DrugCentral:1663	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central		biolink:Association
DrugCentral:1665	biolink:molecularly_interacts_with	UniProtKB:P69905	RO:0002436	drug_central		biolink:Association
DrugCentral:1665	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1665	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1665	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Binding affinity to human adenosine A2A receptor	biolink:Association
DrugCentral:1665	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	Binding affinity to human adenosine A1 receptor	biolink:Association
DrugCentral:1665	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:1667	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1667	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1667	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1667	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1670	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central	Inhibitory constant against HMG-CoA reductase	biolink:Association
DrugCentral:1672	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1672	biolink:molecularly_interacts_with	UniProtKB:P16083	RO:0002436	drug_central	Ability to inhibit 2-[125I]iodomelatonin specific binding to melatonin receptor 3 (MT3) of Syrian hamster brain.	biolink:Association
DrugCentral:1672	biolink:molecularly_interacts_with	UniProtKB:P35398	RO:0002436	drug_central		biolink:Association
DrugCentral:1672	biolink:molecularly_interacts_with	UniProtKB:P49286	RO:0002436	drug_central		biolink:Association
DrugCentral:1672	biolink:molecularly_interacts_with	UniProtKB:P48039	RO:0002436	drug_central		biolink:Association
DrugCentral:1676	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	In vitro for its inhibitory activity against human whole blood Prostaglandin G/H synthase 1	biolink:Association
DrugCentral:1676	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.	biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1677	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1679	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:1679	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1679	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assessed as LDH release after 30 mins	biolink:Association
DrugCentral:1679	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assessed as LDH release after 30 mins	biolink:Association
DrugCentral:1679	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Antagonist activity at recombinant GluN1/GluN2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-induced inward current at -70mV by two-electrode voltage clamp assay	biolink:Association
DrugCentral:1679	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	Antagonist activity at recombinant GluN1/GluN2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-induced inward current at -70mV by two-electrode voltage clamp assay	biolink:Association
DrugCentral:1679	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Inhibition of NMDA NR1/NR2B receptor expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current response by two-electrode voltage clamp assay	biolink:Association
DrugCentral:1679	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:1683	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Competitive inhibition of human recombinant MAO-A expressed in baculovirus infected insect cells using p-tyramine as substrate by Lineweaver-Burk plot analysis	biolink:Association
DrugCentral:1683	biolink:molecularly_interacts_with	UniProtKB:P00390	RO:0002436	drug_central	Inhibitory concentration against human glutathione reductase (In presence of glutathione disulfide)	biolink:Association
DrugCentral:1683	biolink:molecularly_interacts_with	UniProtKB:P30307	RO:0002436	drug_central	Inhibitory concentration for human cell division cycle 25 degree C phosphatase	biolink:Association
DrugCentral:1683	biolink:molecularly_interacts_with	UniProtKB:P30305	RO:0002436	drug_central	Inhibition of MBP-fused recombinant wild type CDC25B3 using fluorescein 3,6 diphosphate as substrate measured for 30 mins in presence of 1 mM dithiothreitol	biolink:Association
DrugCentral:1683	biolink:molecularly_interacts_with	UniProtKB:P15374	RO:0002436	drug_central	Inhibition of UCHL3 in human H1299 cells	biolink:Association
DrugCentral:1683	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Competitive inhibition of human recombinant MAO-B expressed in baculovirus infected insect cells using benzylamine as substrate by Lineweaver-Burk plot analysis	biolink:Association
DrugCentral:1683	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central	Inhibition of purified human recombinant IDO	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1688	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:1689	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1689	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Displacement of [3H]NMS from human M2R expressed in CHOK1 cells after 2 hrs by scintillation counting analysis	biolink:Association
DrugCentral:1689	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Displacement of [3H]NMS from human M3R expressed in CHOK1 cells after 2 hrs by scintillation counting analysis	biolink:Association
DrugCentral:1689	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Mechanism of Action; CHEMBL216; SINGLE PROTEIN	biolink:Association
DrugCentral:1690	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Inhibition of [3H]DAMGO binding to mu-opioid receptor	biolink:Association
DrugCentral:1690	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against potassium channel HERG	biolink:Association
DrugCentral:1690	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:1690	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:1690	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1694	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1695	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1695	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1695	biolink:molecularly_interacts_with	UniProtKB:Q01118	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1695	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1695	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1695	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1695	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1695	biolink:molecularly_interacts_with	UniProtKB:Q9UI33	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1695	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1695	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:1696	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1696	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1696	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1700	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central		biolink:Association
DrugCentral:1700	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central		biolink:Association
DrugCentral:1700	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central		biolink:Association
DrugCentral:1700	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central		biolink:Association
DrugCentral:1700	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central		biolink:Association
DrugCentral:1700	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:1700	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1702	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1704	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1705	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central		biolink:Association
DrugCentral:1706	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1707	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1707	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1707	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1707	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1707	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1707	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1708	biolink:molecularly_interacts_with	UniProtKB:Q06203	RO:0002436	drug_central		biolink:Association
DrugCentral:1708	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:1708	biolink:molecularly_interacts_with	UniProtKB:P51580	RO:0002436	drug_central		biolink:Association
DrugCentral:1708	biolink:molecularly_interacts_with	UniProtKB:P00491	RO:0002436	drug_central		biolink:Association
DrugCentral:1708	biolink:molecularly_interacts_with	UniProtKB:O15439	RO:0002436	drug_central		biolink:Association
DrugCentral:1708	biolink:molecularly_interacts_with	UniProtKB:O15440	RO:0002436	drug_central		biolink:Association
DrugCentral:1710	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central	Mechanism of Action; CHEMBL215; SINGLE PROTEIN	biolink:Association
DrugCentral:1710	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1710	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1710	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1712	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1714	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central	DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A)	biolink:Association
DrugCentral:1714	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1714	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1714	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	biolink:Association
DrugCentral:1720	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nM	biolink:Association
DrugCentral:1721	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHOK1 cells after 60 mins	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Evaluated for the binding affinity to porcine choroid plexus at 5-hydroxytryptamine 2C receptor binding site by using [3H]-MES as a radioligand.	biolink:Association
DrugCentral:1723	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	Displacement of [3H]5CT from 5HT7 receptor	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central	Inhibition of DPP4	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O00217	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O00483	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O14561	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O15239	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O43181	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O43674	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O43676	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O43677	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O43678	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O43920	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O75251	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O75306	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O75380	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O75438	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O75489	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O95139	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O95167	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O95168	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O95169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O95178	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O95182	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O95298	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O95299	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O96000	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P03886	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P03891	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P03897	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P03901	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P03905	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P03915	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P03923	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P17568	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P19404	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P28331	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P49821	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P51970	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P56181	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:P56556	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q16718	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q16795	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q86Y39	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q8N183	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q9BU61	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q9NRX3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q9NX14	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q9P032	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q9P0J0	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q9UI09	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q9Y375	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q9Y6M9	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363065; PROTEIN COMPLEX	biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:Q9Y478	RO:0002436	drug_central		biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O75751	RO:0002436	drug_central		biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:1725	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central		biolink:Association
DrugCentral:1726	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Inhibition of binding of [3H]quinuclidinyl benzilate to muscarinic receptors in membranes of CHO cells transfected with Muscarinic acetylcholine receptor M2	biolink:Association
DrugCentral:1726	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	Inhibition of binding of [3H]quinuclidinyl benzilate to muscarinic receptors in membranes of CHO cells transfected with Muscarinic acetylcholine receptor M4	biolink:Association
DrugCentral:1726	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Mechanism of Action; CHEMBL245; SINGLE PROTEIN	biolink:Association
DrugCentral:1726	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1728	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligand	biolink:Association
DrugCentral:1728	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligand	biolink:Association
DrugCentral:1728	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against potassium channel HERG	biolink:Association
DrugCentral:1728	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1728	biolink:molecularly_interacts_with	UniProtKB:Q9GZZ6	RO:0002436	drug_central		biolink:Association
DrugCentral:1728	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:1729	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against potassium channel HERG	biolink:Association
DrugCentral:1729	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1732	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central	Activation of human TAAR1 expressed in human HEK293T cells assessed as cAMP accumulation after 10 mins by BRET assay	biolink:Association
DrugCentral:1732	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity towards sigma opioid receptor in guinea pig cerebral homogenate using [3H]DTG as radioligand	biolink:Association
DrugCentral:1732	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1732	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1732	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1732	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1732	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1732	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1732	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1736	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1736	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1736	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1736	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1736	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1738	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1739	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central		biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1740	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VA	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Evaluated for its activity against carbonic anhydrase (CA) in anesthetized rabbits	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase II	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Ki value against human carbonic anhydrase VII	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Ki value against human carbonic anhydrase XII (hCA XII)	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase IX (hCA IX) by using CO2 hydrase assay method	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of cloned isozyme, human carbonic anhydrase IV	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assay	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VB	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant cytosolic carbonic anhydrase 13 preincubated for 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:1741	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of full length human recombinant CA VI	biolink:Association
DrugCentral:1742	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action; CHEMBL231; SINGLE PROTEIN	biolink:Association
DrugCentral:1745	biolink:molecularly_interacts_with	UniProtKB:P07202	RO:0002436	drug_central		biolink:Association
DrugCentral:1745	biolink:molecularly_interacts_with	UniProtKB:P22079	RO:0002436	drug_central	Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC	biolink:Association
DrugCentral:1747	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central		biolink:Association
DrugCentral:1748	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:1748	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:1748	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1748	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1748	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1748	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central		biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:O15439	RO:0002436	drug_central		biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:O15440	RO:0002436	drug_central		biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central	Inhibition of human TS by spectrophotometric analysis	biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:Q05932	RO:0002436	drug_central	Compound was evaluated for the inhibitory activity against Folyl-polyglutamate synthase from CCRF-CEM human leukemia cells.	biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:P41440	RO:0002436	drug_central	Affinity towards RFC measured by the inhibition of [3H]MTX uptake	biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:P15328	RO:0002436	drug_central		biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:Q96NT5	RO:0002436	drug_central		biolink:Association
DrugCentral:1751	biolink:molecularly_interacts_with	UniProtKB:P14207	RO:0002436	drug_central		biolink:Association
DrugCentral:1752	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1753	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:1753	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1753	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1754	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:1757	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1757	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1757	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1757	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1757	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	Displacement of [3H]N-methylscopolamine from human muscarinic M5 receptor expressed in CHO cells after 120 mins by scintillation counting	biolink:Association
DrugCentral:1758	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362995; PROTEIN FAMILY	biolink:Association
DrugCentral:1758	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362995; PROTEIN FAMILY	biolink:Association
DrugCentral:1758	biolink:molecularly_interacts_with	UniProtKB:Q9P0X4	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362995; PROTEIN FAMILY	biolink:Association
DrugCentral:1759	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central	Mechanism of Action; CHEMBL1876; SINGLE PROTEIN	biolink:Association
DrugCentral:1761	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central		biolink:Association
DrugCentral:1762	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1762	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1762	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1762	biolink:molecularly_interacts_with	UniProtKB:P20711	RO:0002436	drug_central		biolink:Association
DrugCentral:1762	biolink:molecularly_interacts_with	UniProtKB:B2RXH2	RO:0002436	drug_central		biolink:Association
DrugCentral:1763	biolink:molecularly_interacts_with	UniProtKB:P00390	RO:0002436	drug_central	Inhibitory concentration against human glutathione reductase	biolink:Association
DrugCentral:1763	biolink:molecularly_interacts_with	UniProtKB:P10636	RO:0002436	drug_central	Inhibition of human recombinant brain tau protein (412 amino acid residues) filament assembly expressed in Escherichia coli BL21(DE3) by electron microscopic analysis in presence of heparin	biolink:Association
DrugCentral:1763	biolink:molecularly_interacts_with	UniProtKB:Q16881	RO:0002436	drug_central	Inhibition of human recombinant TrxR1 at pH 7.4	biolink:Association
DrugCentral:1763	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central		biolink:Association
DrugCentral:1763	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central		biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1764	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in CHO cells by liquid scintillation counting	biolink:Association
DrugCentral:1765	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:1765	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:1765	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1765	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1765	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central	Blockage of Nicotinic acetylcholine receptor alpha-7 noncompetitively in hippocampal primary cultures	biolink:Association
DrugCentral:1766	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:1766	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:1766	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:1766	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:1766	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:1766	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:1767	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1767	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1767	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1767	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Displacement of [125I]RTI-55 from human DAT expressing HEK293 cells	biolink:Association
DrugCentral:1767	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Displacement of [125I]RTI-55 from human NET expressing HEK293 cells	biolink:Association
DrugCentral:1767	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Displacement of [125I]RTI-55 from human SERT expressing HEK293 cells	biolink:Association
DrugCentral:1768	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:1768	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:1770	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1771	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:1774	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1774	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1774	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	The compound was tested for affinity towards sigma-3 receptor	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Displacement of [3H]ketanserin from human 5HT2AR expressed in HEK-293 cells	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Displacement of [3H]mesulergine from human HTR2B expressed in CHO-K1 cells	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Displacement of [3H]mesulergine from human HTR2B expressed in HEK-293 cells	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:Q07820	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide. (Class of assay: confirmatory) [Related pubchem assays: 2090 (Summary AID.), 2057 (Screening assay (MCL1 inhibitors).), 2168 (Screening assay (MCL1 inhibitors).)]	biolink:Association
DrugCentral:1775	biolink:molecularly_interacts_with	UniProtKB:Q07817	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Counterscreen for inhibitors of MCL1: fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of BCL2-related protein, long isoform (BCLXL). (Class of assay: confirmatory) [Related pubchem assays: 2129 (Screening assay (BCLXL inhibitors).), 2057 (Screening assay (MCL-1 inhibitors).), 2144 (Summary AID.), 2166 (Screening assay (BCLXL inhibitors).)]	biolink:Association
DrugCentral:1779	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Mechanism of Action; CHEMBL213; SINGLE PROTEIN	biolink:Association
DrugCentral:1779	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Mechanism of Action; CHEMBL210; SINGLE PROTEIN	biolink:Association
DrugCentral:1780	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Mechanism of Action; CHEMBL216; SINGLE PROTEIN	biolink:Association
DrugCentral:1780	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Mechanism of Action; CHEMBL225; SINGLE PROTEIN	biolink:Association
DrugCentral:1781	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central	Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetry	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:Q13639	RO:0002436	drug_central		biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:A5X5Y0	RO:0002436	drug_central	Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heart	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:O95264	RO:0002436	drug_central	Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heart	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heart	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:Q70Z44	RO:0002436	drug_central	Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heart	biolink:Association
DrugCentral:1782	biolink:molecularly_interacts_with	UniProtKB:Q8WXA8	RO:0002436	drug_central	Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heart	biolink:Association
DrugCentral:1783	biolink:molecularly_interacts_with	UniProtKB:Q13621	RO:0002436	drug_central		biolink:Association
DrugCentral:1783	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1783	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central	Mechanism of Action; CHEMBL1876; SINGLE PROTEIN	biolink:Association
DrugCentral:1786	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1786	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1791	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:1791	biolink:molecularly_interacts_with	UniProtKB:P15538	RO:0002436	drug_central	Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrate	biolink:Association
DrugCentral:1791	biolink:molecularly_interacts_with	UniProtKB:P19099	RO:0002436	drug_central	Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate	biolink:Association
DrugCentral:1792	biolink:molecularly_interacts_with	UniProtKB:P07101	RO:0002436	drug_central		biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central		biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central	Inhibition of human recombinant Nav1.8 channel expressed in HEK293 cells by whole cell voltage clamp technique	biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Binding affinity to inactivated human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assay	biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of human recombinant Nav1.2 channel expressed in HEK293 cells by whole cell voltage clamp technique	biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:Q8IWT1	RO:0002436	drug_central		biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:Q9NY72	RO:0002436	drug_central		biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:O60939	RO:0002436	drug_central		biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:Q07699	RO:0002436	drug_central		biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:1794	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P02768	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P10145	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P10632	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P14778	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P34972	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P41222	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:Q13258	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:Q9HCR9	RO:0002436	drug_central		biolink:Association
DrugCentral:1795	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y4	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT3 radioligand binding (ligand: [3H] GR-65630)	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Inhibition of [125I]iodosulpiride binding to human Dopamine receptor D3	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Inhibition of [3H]-spiperone binding to human Dopamine receptor D2	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding affinity for human cloned Dopamine receptor D4	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding affinity for human cloned Alpha-1A adrenergic receptor	biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1796	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:Q8NEC5	RO:0002436	drug_central	Patch clamp electrophysiology, kinetic rapid mixing fluometry	biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:Q96P56	RO:0002436	drug_central	Patch clamp electrophysiology and kinetic rapid mixing fluometry.	biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:Q86XQ3	RO:0002436	drug_central	Patch clamp electrophysiology, kinetic rapid mixing fluometry.	biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:Q7RTX7	RO:0002436	drug_central	Patch clamp electrophysiology, kinetic rapid mixing fluometry.	biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:Q9P0X4	RO:0002436	drug_central	Inhibition of T-type calcium channel alpha1I by FLIPR	biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central	Inhibition of human Cav3.1 alpha1G expressed in HEK293 cells assessed as inhibition of calcium influx by FLIPR assay	biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Binding affinity at hERG expressed in HEK293 cells by fluorescence polarization assay	biolink:Association
DrugCentral:1797	biolink:molecularly_interacts_with	UniProtKB:Q00975	RO:0002436	drug_central	Inhibition of N-type calcium channel Alpha-1B	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central	DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P50052	RO:0002436	drug_central	DRUGMATRIX: Angiotensin AT2 radioligand binding (ligand: [125I] CGP-42112A)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P41968	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of human placental microsome CYP19	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P40925	RO:0002436	drug_central	Inhibition of malate dehydrogenase (MDH)	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P05093	RO:0002436	drug_central	In vitro inhibition of human Cytochrome P450 17A1 activity	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P05186	RO:0002436	drug_central	PUBCHEM_BIOASSAY: uHTS identification of compounds activating TNAP in the absence of phosphate acceptor performed in luminescent assay. (Class of assay: confirmatory) [Related pubchem assays: 813, 518, 1548, 1450 ]	biolink:Association
DrugCentral:1800	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:1802	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1803	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1803	biolink:molecularly_interacts_with	UniProtKB:P07900	RO:0002436	drug_central		biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Antagonist activity at estrogen receptor by Gal4-DNA binding domain-hormone receptor LBD one-hybrid assay	biolink:Association
DrugCentral:1805	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Displacement of [3H]E2 from human ERbeta after 16 hrs by scintillation counting	biolink:Association
DrugCentral:1806	biolink:molecularly_interacts_with	UniProtKB:O43451	RO:0002436	drug_central	Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assay	biolink:Association
DrugCentral:1806	biolink:molecularly_interacts_with	UniProtKB:P09848	RO:0002436	drug_central	Inhibition of lactase by HPLC	biolink:Association
DrugCentral:1806	biolink:molecularly_interacts_with	UniProtKB:P10253	RO:0002436	drug_central	Inhibition of human lysosomal alpha-glucosidase	biolink:Association
DrugCentral:1806	biolink:molecularly_interacts_with	UniProtKB:P04062	RO:0002436	drug_central	Inhibition of human lysosomal beta-glucosidase	biolink:Association
DrugCentral:1806	biolink:molecularly_interacts_with	UniProtKB:P14410	RO:0002436	drug_central	Inhibition of sucrase by HPLC	biolink:Association
DrugCentral:1806	biolink:molecularly_interacts_with	UniProtKB:P04746	RO:0002436	drug_central		biolink:Association
DrugCentral:1807	biolink:molecularly_interacts_with	UniProtKB:Q16739	RO:0002436	drug_central		biolink:Association
DrugCentral:1807	biolink:molecularly_interacts_with	UniProtKB:O43451	RO:0002436	drug_central	Inhibition of Glycosidases (maltase) in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method maltase	biolink:Association
DrugCentral:1807	biolink:molecularly_interacts_with	UniProtKB:P35573	RO:0002436	drug_central	Inhibition of glycogen glycogen de-branching enzyme by HPLC	biolink:Association
DrugCentral:1807	biolink:molecularly_interacts_with	UniProtKB:P10253	RO:0002436	drug_central	Inhibition of human lysosomal alpha glucosidase	biolink:Association
DrugCentral:1807	biolink:molecularly_interacts_with	UniProtKB:Q9HCG7	RO:0002436	drug_central	Inhibition of human GBA2	biolink:Association
DrugCentral:1807	biolink:molecularly_interacts_with	UniProtKB:P14410	RO:0002436	drug_central	Inhibition of sucrase by HPLC	biolink:Association
DrugCentral:1808	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Inhibition of human DAT	biolink:Association
DrugCentral:1808	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1808	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1808	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central		biolink:Association
DrugCentral:1809	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of canine cardiac cAMP phosphodiesterase (cAMP-PDE)	biolink:Association
DrugCentral:1809	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibition of canine cardiac cAMP phosphodiesterase (cAMP-PDE)	biolink:Association
DrugCentral:1809	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Inhibition of canine cardiac cAMP phosphodiesterase (cAMP-PDE)	biolink:Association
DrugCentral:1809	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of canine cardiac cAMP phosphodiesterase (cAMP-PDE)	biolink:Association
DrugCentral:1809	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central	Inhibitory activity against cGMP-phosphodiesterase from porcine aorta	biolink:Association
DrugCentral:1809	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Inhibitory concentration required to inhibit human phosphodiesterase 3B expressed in Escherichia coli	biolink:Association
DrugCentral:1809	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Inhibitory concentration required to inhibit human phosphodiesterase 3A expressed in Escherichia coli	biolink:Association
DrugCentral:1809	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Inhibition of human phosphodiesterase 3	biolink:Association
DrugCentral:1809	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Inhibition of human phosphodiesterase 3	biolink:Association
DrugCentral:1810	biolink:molecularly_interacts_with	UniProtKB:P31749	RO:0002436	drug_central	Inhibition of Akt phosphorylation in human insulin-stimulated A549 cells incubated for 2 hrs prior to insulin-induction measured after 30 mins by ELISA	biolink:Association
DrugCentral:1810	biolink:molecularly_interacts_with	UniProtKB:P30304	RO:0002436	drug_central	Inhibition of Cell division cycle 25 (Cdc25) phosphatase	biolink:Association
DrugCentral:1811	biolink:molecularly_interacts_with	UniProtKB:P14679	RO:0002436	drug_central		biolink:Association
DrugCentral:1811	biolink:molecularly_interacts_with	UniProtKB:P34896	RO:0002436	drug_central		biolink:Association
DrugCentral:1812	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of AChE	biolink:Association
DrugCentral:1812	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Binding affinity towards muscarinic M1 receptor	biolink:Association
DrugCentral:1814	biolink:molecularly_interacts_with	UniProtKB:O60706	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095198; PROTEIN COMPLEX	biolink:Association
DrugCentral:1814	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095198; PROTEIN COMPLEX	biolink:Association
DrugCentral:1814	biolink:molecularly_interacts_with	UniProtKB:P48048	RO:0002436	drug_central		biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Inhibition of [125I]iodosulpiride binding to human Dopamine receptor D3	biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	Inhibition of [3H]5-HT binding to human 5-hydroxytryptamine 7 receptor	biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.	biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Inhibition of [3H]rauwolscine binding to Alpha-2C adrenergic receptor	biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Displacement of [3H]GR65630 from human 5-HT3A receptor expressed in HEK293 cells by liquid scintillation counting analysis	biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Inhibition of [3H]mesulergine binding to human 5-hydroxytryptamine 2C receptor	biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Inhibition of [125I]R91150 binding to human 5-hydroxytryptamine 2A receptor	biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity to 5HT1A receptor	biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Inhibition of [3H]rauwolscine binding to Alpha-2A adrenergic receptor	biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding affinity at human Alpha-1A adrenergic receptor in CHO cells uby [3H]prazosin (0.25 nM) displacement.	biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1816	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1817	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:1817	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central		biolink:Association
DrugCentral:1817	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central		biolink:Association
DrugCentral:1817	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central		biolink:Association
DrugCentral:1818	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	inside-out patches in COS-1 cells	biolink:Association
DrugCentral:1818	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	inside-out patches in COS-1 cells	biolink:Association
DrugCentral:1819	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central	Uncompetitive inhibition of hexahistidyl-tagged human IDO1	biolink:Association
DrugCentral:1820	biolink:molecularly_interacts_with	UniProtKB:P15538	RO:0002436	drug_central		biolink:Association
DrugCentral:1820	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1820	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1820	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1820	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1820	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1820	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1820	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1820	biolink:molecularly_interacts_with	UniProtKB:P05108	RO:0002436	drug_central	Mechanism of Action; CHEMBL2033; SINGLE PROTEIN	biolink:Association
DrugCentral:1820	biolink:molecularly_interacts_with	UniProtKB:P10109	RO:0002436	drug_central		biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central		biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:O75751	RO:0002436	drug_central	Inhibition of human OCT3-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of human OCT1-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central	Inhibition of BTK (unknown origin)	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P11309	RO:0002436	drug_central	Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli BL21(DE3) after 1 hr by HTRF assay	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells up to 500 uM after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated [14]-metformin uptake expressed in polarized MDCK2 cells after 5 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:1821	biolink:molecularly_interacts_with	UniProtKB:P29372	RO:0002436	drug_central		biolink:Association
DrugCentral:1822	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:1822	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:1822	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:1822	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:1824	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central		biolink:Association
DrugCentral:1824	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1824	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1825	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of human MAO-A expressed in BTI insect cells using p-tyramine as substrate after 60 mins	biolink:Association
DrugCentral:1825	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:1825	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Inhibition of human MAO-B expressed in BTI insect cells using p-tyramine as substrate after 60 mins	biolink:Association
DrugCentral:1825	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity to 5HT1A receptor	biolink:Association
DrugCentral:1826	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1826	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central		biolink:Association
DrugCentral:1826	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central		biolink:Association
DrugCentral:1826	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1826	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1827	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Inhibitory activity against angiotensin I converting enzyme (ACE)	biolink:Association
DrugCentral:1829	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX1	biolink:Association
DrugCentral:1829	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition of COX2	biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 7 receptor	biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1830	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:1832	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:1832	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1832	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1834	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:1834	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:1834	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1834	biolink:molecularly_interacts_with	UniProtKB:P14679	RO:0002436	drug_central	Mechanism of Action; CHEMBL1973; SINGLE PROTEIN	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central		biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:P10632	RO:0002436	drug_central		biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:Q9NS75	RO:0002436	drug_central		biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:Q13304	RO:0002436	drug_central	Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assay	biolink:Association
DrugCentral:1836	biolink:molecularly_interacts_with	UniProtKB:Q9Y271	RO:0002436	drug_central	GRAC: human CysLT1 selective antagonist	biolink:Association
DrugCentral:1837	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1837	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1837	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1842	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1845	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1845	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1845	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:1845	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:Q13639	RO:0002436	drug_central		biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:1848	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG expressed in HEK293 cells by whole cell patch clamp method	biolink:Association
DrugCentral:1852	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1856	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:1856	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Binding affinity for human Alpha-2C adrenergic receptor	biolink:Association
DrugCentral:1856	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central	Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2AR	biolink:Association
DrugCentral:1856	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Binding affinity for human Alpha-2A adrenergic receptor	biolink:Association
DrugCentral:1857	biolink:molecularly_interacts_with	UniProtKB:P41252	RO:0002436	drug_central	Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetase	biolink:Association
DrugCentral:1859	biolink:molecularly_interacts_with	UniProtKB:P12268	RO:0002436	drug_central		biolink:Association
DrugCentral:1859	biolink:molecularly_interacts_with	UniProtKB:P20839	RO:0002436	drug_central		biolink:Association
DrugCentral:1860	biolink:molecularly_interacts_with	UniProtKB:P12268	RO:0002436	drug_central	Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II isoform); Range is 6-10 nM	biolink:Association
DrugCentral:1860	biolink:molecularly_interacts_with	UniProtKB:P20839	RO:0002436	drug_central	Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I isoform); Range is 33-37 nM	biolink:Association
DrugCentral:1860	biolink:molecularly_interacts_with	UniProtKB:P12268	RO:0002436	drug_central	Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenase	biolink:Association
DrugCentral:1860	biolink:molecularly_interacts_with	UniProtKB:P20839	RO:0002436	drug_central	Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenase	biolink:Association
DrugCentral:1862	biolink:molecularly_interacts_with	UniProtKB:P34972	RO:0002436	drug_central	Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells by liquid scintillation counting	biolink:Association
DrugCentral:1862	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central	Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cells by liquid scintillation counting	biolink:Association
DrugCentral:1863	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1863	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1863	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:1863	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Mechanism of Action; CHEMBL230; SINGLE PROTEIN	biolink:Association
DrugCentral:1863	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1865	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1865	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1865	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:P05981	RO:0002436	drug_central		biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:Q04756	RO:0002436	drug_central		biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	Compound was evaluated for inhibitory activity against Thrombin.	biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central	Compound was evaluated for inhibitory activity against plasmin.	biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:P07477	RO:0002436	drug_central	In vitro for inhibition of purified bovine trypsin.	biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:P00736	RO:0002436	drug_central	Inhibition of C1r serine protease	biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:P09871	RO:0002436	drug_central	Compound was evaluated for inhibitory activity against C1s serine protease. 	biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:P06870	RO:0002436	drug_central	Compound was evaluated for inhibitory activity against Kallikrein.	biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:P00742	RO:0002436	drug_central	Inhibitory concentration against Coagulation factor X	biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:Q16515	RO:0002436	drug_central		biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:P78348	RO:0002436	drug_central		biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:Q9UHC3	RO:0002436	drug_central		biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:Q15661	RO:0002436	drug_central		biolink:Association
DrugCentral:1867	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y6	RO:0002436	drug_central		biolink:Association
DrugCentral:1868	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central		biolink:Association
DrugCentral:1870	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Displacement of [3H]ketanserin from 5HT2A receptor expressed in HEK293 cells by liquid scintillation spectrophotometry	biolink:Association
DrugCentral:1872	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand	biolink:Association
DrugCentral:1872	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central	Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand	biolink:Association
DrugCentral:1872	biolink:molecularly_interacts_with	UniProtKB:Q14534	RO:0002436	drug_central		biolink:Association
DrugCentral:1873	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:1873	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1873	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1874	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:1874	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:1874	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1875	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1876	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Displacement of [3H]U69593 form human kappa opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:1876	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Activity at human delta opioid receptor by [35S]GTPgammaS binding assay	biolink:Association
DrugCentral:1876	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Activity at human mu opioid receptor by [35S]GTPgammaS binding assay	biolink:Association
DrugCentral:1877	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Displacement of [3H]U69593 form human kappa opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:1877	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Displacement of [3H]Naltrindole form human delta opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:1877	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Displacement of [3H]DAMGO form human mu opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:1877	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Inhibition of specific binding of [3H]NANM of sigma receptor in Guinea pig brain membranes	biolink:Association
DrugCentral:1878	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:1878	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:1878	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1878	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1878	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:1879	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1879	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1879	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1879	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:1881	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Mechanism of Action; CHEMBL1871; SINGLE PROTEIN	biolink:Association
DrugCentral:1881	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central	Binding affinity to human CBG receptor (corticosteroid-binding globulins)	biolink:Association
DrugCentral:1881	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1881	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1882	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1882	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:1883	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central	Inhibition of recombinant human AKR1C3	biolink:Association
DrugCentral:1883	biolink:molecularly_interacts_with	UniProtKB:P52895	RO:0002436	drug_central	Inhibition of human recombinant N-terminal His6-tagged AKR1C2 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one as substrate after 1 hr by fluorimetric analysis	biolink:Association
DrugCentral:1883	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition activity against recombinant human Prostaglandin G/H synthase 2	biolink:Association
DrugCentral:1883	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1884	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1884	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:1884	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1884	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptor	biolink:Association
DrugCentral:1884	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central	In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor	biolink:Association
DrugCentral:1886	biolink:molecularly_interacts_with	UniProtKB:O60706	RO:0002436	drug_central		biolink:Association
DrugCentral:1886	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:1886	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central		biolink:Association
DrugCentral:1886	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:1887	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1887	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1887	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1889	biolink:molecularly_interacts_with	UniProtKB:Q9HC97	RO:0002436	drug_central	GPR35a–beta-arrestin-2 interaction assays performed using a CHO–K1 cell line stably expressing human GPR35 and beta-arrestin-2	biolink:Association
DrugCentral:1889	biolink:molecularly_interacts_with	UniProtKB:Q9Y271	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:1890	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1891	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1891	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1891	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1891	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1891	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1891	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1891	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:1893	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of human MDR1-dependent accumulation of calcein-AM expressed in MDCK2 cells	biolink:Association
DrugCentral:1895	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1895	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding Affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligand	biolink:Association
DrugCentral:1897	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central		biolink:Association
DrugCentral:1897	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central	Inhibition of human plasma BChE pretreated for 30 mins by Ellman technique	biolink:Association
DrugCentral:1899	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:1899	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1900	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:1901	biolink:molecularly_interacts_with	UniProtKB:P16066	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1906	biolink:molecularly_interacts_with	UniProtKB:Q9NTG7	RO:0002436	drug_central	Inhibition of human recombinant SIRT3 after 60 mins by fluorimetric analysis	biolink:Association
DrugCentral:1906	biolink:molecularly_interacts_with	UniProtKB:Q8IXJ6	RO:0002436	drug_central	Inhibition of recombinant SIRT2 using ZMAL substrate after 4 hrs by homogeneous fluorescence assay	biolink:Association
DrugCentral:1906	biolink:molecularly_interacts_with	UniProtKB:Q9NXA8	RO:0002436	drug_central	Inhibition of SIRT5 using ZK(suc)A substrate after 1 hr by homogeneous fluorescence assay	biolink:Association
DrugCentral:1906	biolink:molecularly_interacts_with	UniProtKB:Q96EB6	RO:0002436	drug_central	Inhibition of recombinant SIRT1 using ZMAL substrate after 4 hrs by homogeneous fluorescence assay	biolink:Association
DrugCentral:1906	biolink:molecularly_interacts_with	UniProtKB:Q8TDS4	RO:0002436	drug_central		biolink:Association
DrugCentral:1906	biolink:molecularly_interacts_with	UniProtKB:P49019	RO:0002436	drug_central		biolink:Association
DrugCentral:1906	biolink:molecularly_interacts_with	UniProtKB:Q15274	RO:0002436	drug_central		biolink:Association
DrugCentral:1906	biolink:molecularly_interacts_with	UniProtKB:P40261	RO:0002436	drug_central		biolink:Association
DrugCentral:1909	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:1909	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:1909	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:1909	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1909	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of P-glycoprotein expressed in A2780/ADR cells by calcein AM assay	biolink:Association
DrugCentral:1909	biolink:molecularly_interacts_with	UniProtKB:P40925	RO:0002436	drug_central	Inhibition of malate dehydrogenase (MDH)	biolink:Association
DrugCentral:1909	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Displacement of [125]AB-MECA binding to human Adenosine A3 receptor expressed in HEK cells	biolink:Association
DrugCentral:1909	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central	Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells by Hoechst 33342 assay	biolink:Association
DrugCentral:1909	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1909	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Inhibition of EGFR after 60 mins by radiometric assay	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:P31749	RO:0002436	drug_central	Inhibition of Akt1 after 60 mins by radiometric assay	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of VEGFR2 after 60 mins by radiometric assay	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Inhibition of Src kinase	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Inhibition of TIE2 after 60 mins by radiometric assay	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Inhibition of JAK2	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:P40763	RO:0002436	drug_central	Inhibition of STAT3 in human HeLa cells after 24 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Inhibition of Aurora-A after 60 mins by radiometric assay	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:O15530	RO:0002436	drug_central	Inhibition of PDK1 after 60 mins by radiometric assay	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	Inhibition of FGFR-1 after 60 mins by radiometric assay	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Inhibition of KIT after 60 mins by radiometric assay	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:P49841	RO:0002436	drug_central	Inhibition of GSK3-beta after 60 mins by radiometric assay	biolink:Association
DrugCentral:1912	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Inhibition of LYN after 60 mins by radiometric assay	biolink:Association
DrugCentral:1919	biolink:molecularly_interacts_with	UniProtKB:P16066	RO:0002436	drug_central		biolink:Association
DrugCentral:1919	biolink:molecularly_interacts_with	UniProtKB:P48048	RO:0002436	drug_central		biolink:Association
DrugCentral:1919	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	Binding affinity to alpha-1-beta-gamma-delta nicotinic receptor	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P07510	RO:0002436	drug_central	Binding affinity to alpha-1-beta-gamma-delta nicotinic receptor	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central	Binding affinity to alpha-1-beta-gamma-delta nicotinic receptor	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central	Binding affinity to alpha-1-beta-gamma-delta nicotinic receptor	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:A5X5Y0	RO:0002436	drug_central	In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determined	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:O95264	RO:0002436	drug_central	In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determined	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determined	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:Q70Z44	RO:0002436	drug_central	In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determined	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:Q8WXA8	RO:0002436	drug_central	In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determined	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta1 nicotinic acetylcholine receptor subunits	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central		biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central		biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P11509	RO:0002436	drug_central		biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:Q9UK17	RO:0002436	drug_central		biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central		biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:O75762	RO:0002436	drug_central	Patch clamp	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	Displacement of [3H]epibatidine from alpha2beta2 nAChR after 4 hrs by liquid scintillation counting analysis	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central	Displacement of [3H]epibatidine from alpha2beta2 nAChR after 4 hrs by liquid scintillation counting analysis	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central	Displacement of [3H]epibatidine from alpha4beta4 nAChR after 4 hrs by liquid scintillation counting analysis	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central	Displacement of [3H]epibatidine from alpha4beta4 nAChR after 4 hrs by liquid scintillation counting analysis	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central	Inhibition of [3H]nicotine binding to alpha3 nicotinic acetylcholine receptor in Homo sapiens (human) SH-SY5Y cells co-expressing beta2beta4alpha5 Nicotinic acetylcholine receptor subunits	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central	Displacement of [3H]epibatidine from alpha2beta4 nAChR after 4 hrs by liquid scintillation counting analysis	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central	Displacement of [3H]epibatidine from alpha2beta4 nAChR after 4 hrs by liquid scintillation counting analysis	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	Antagonist activity at human alpha6/alpha3beta2beta3 nAChR expressed in human SHEP1 cells assessed as inhibition of carbamylcholine-induced 86Rb+ ion efflux preincubated for 10 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central	Antagonist activity at human alpha6/alpha3beta2beta3 nAChR expressed in human SHEP1 cells assessed as inhibition of carbamylcholine-induced 86Rb+ ion efflux preincubated for 10 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:Q05901	RO:0002436	drug_central	Antagonist activity at human alpha6/alpha3beta2beta3 nAChR expressed in human SHEP1 cells assessed as inhibition of carbamylcholine-induced 86Rb+ ion efflux preincubated for 10 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:1920	biolink:molecularly_interacts_with	UniProtKB:Q15825	RO:0002436	drug_central	Antagonist activity at human alpha6/alpha3beta2beta3 nAChR expressed in human SHEP1 cells assessed as inhibition of carbamylcholine-induced 86Rb+ ion efflux preincubated for 10 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Recombinant Cav1.3 calcium channel complexes expressed in tsA-cells	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:O60840	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX)	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP)	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P41597	RO:0002436	drug_central	DRUGMATRIX: Chemokine CCR2B  radioligand binding (ligand: [125I] MCP-1)	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P16389	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central	GRAC: human Glycine receptor subunit alpha-1 selective antagonist	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibition of [125I]- AB-MECA binding to human Adenosine A3 receptors expressed in HEK cells	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P00390	RO:0002436	drug_central	Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranes	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central	Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp technique	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Binding affinity for HA-tagged mutant human Adenosine A2A receptor (V84L), using [3H]CGS-21680 as radioligand expressed in COS-7 cells	biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:O75311	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:P48167	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:Q15746	RO:0002436	drug_central		biolink:Association
DrugCentral:1922	biolink:molecularly_interacts_with	UniProtKB:Q13698	RO:0002436	drug_central		biolink:Association
DrugCentral:1923	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1923	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against IKr potassium channel	biolink:Association
DrugCentral:1923	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1923	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated [14]-metformin uptake expressed in polarized MDCK2 cells after 5 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:1925	biolink:molecularly_interacts_with	UniProtKB:P51800	RO:0002436	drug_central		biolink:Association
DrugCentral:1925	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:1925	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:1925	biolink:molecularly_interacts_with	UniProtKB:Q9HC97	RO:0002436	drug_central	Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysis	biolink:Association
DrugCentral:1925	biolink:molecularly_interacts_with	UniProtKB:P51801	RO:0002436	drug_central		biolink:Association
DrugCentral:1925	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:1925	biolink:molecularly_interacts_with	UniProtKB:Q6UVM3	RO:0002436	drug_central		biolink:Association
DrugCentral:1928	biolink:molecularly_interacts_with	UniProtKB:P40763	RO:0002436	drug_central	Inhibition of STAT3 expressed in human U3A cells after 1 hr by luciferase reporter gene assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central		biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P51813	RO:0002436	drug_central		biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central		biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central		biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central		biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Binding constant for JNK3 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding affinity to human FLT3	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding affinity to human ABL1	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P45984	RO:0002436	drug_central	Binding constant for JNK2 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Binding affinity to human PDGFRalpha	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central	Binding constant for EPHB4 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q9NYL2	RO:0002436	drug_central	Binding constant for ZAK kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P04049	RO:0002436	drug_central	Binding constant for RAF1 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P21709	RO:0002436	drug_central	Binding constant for EPHA1 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for HPK1 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P15056	RO:0002436	drug_central	Binding constant for BRAF(V600E) kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P49759	RO:0002436	drug_central	Binding constant for CLK1 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P29322	RO:0002436	drug_central	Binding constant for EPHA8 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P29317	RO:0002436	drug_central	Binding constant for EPHA2 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Binding constant for EPHA3 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central	Binding constant for CSK kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q7L7X3	RO:0002436	drug_central	Binding constant for TAOK1 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q59H18	RO:0002436	drug_central	Binding constant for TNNI3K kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding affinity to human PDGFRbeata	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q8TBX8	RO:0002436	drug_central	Binding constant for PIP5K2C kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding affinity to human c-Kit	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Binding constant for EPHA6 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q9HAZ1	RO:0002436	drug_central	Binding constant for CLK4 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P54756	RO:0002436	drug_central	Binding constant for EPHA5 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P54764	RO:0002436	drug_central	Binding constant for EPHA4 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central	Binding constant for EPHB1 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central	Binding constant for TRKC kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q9Y5S2	RO:0002436	drug_central	Binding constant for MRCKB kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding constant for TIE2 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P45983	RO:0002436	drug_central	Binding constant for JNK1 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q9H2K8	RO:0002436	drug_central	Binding constant for TAOK3 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central	Binding affinity to wild type DDR2 (unknown origin) by FLiK assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central	Binding constant for TRKB kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P29323	RO:0002436	drug_central	Binding constant for EPHB2 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q15759	RO:0002436	drug_central	Binding constant for p38-beta kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P54753	RO:0002436	drug_central	Binding constant for EPHB3 kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	Binding constant for p38-alpha kinase domain	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Inhibition of Bcr-Abl kinase (unknown origin) after 30 mins by HTRF assay	biolink:Association
DrugCentral:1932	biolink:molecularly_interacts_with	UniProtKB:P11274	RO:0002436	drug_central	Inhibition of Bcr-Abl kinase (unknown origin) after 30 mins by HTRF assay	biolink:Association
DrugCentral:1933	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysate	biolink:Association
DrugCentral:1934	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1934	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1934	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central		biolink:Association
DrugCentral:1934	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:1934	biolink:molecularly_interacts_with	UniProtKB:Q06432	RO:0002436	drug_central		biolink:Association
DrugCentral:1935	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1935	biolink:molecularly_interacts_with	UniProtKB:P03956	RO:0002436	drug_central	DRUGMATRIX: Peptidase, Matrix Metalloproteinase-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:1935	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 production	biolink:Association
DrugCentral:1935	biolink:molecularly_interacts_with	UniProtKB:P05164	RO:0002436	drug_central	Inhibition of recombinant human myeloperoxidase	biolink:Association
DrugCentral:1935	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central		biolink:Association
DrugCentral:1935	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:1935	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central		biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central		biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central	DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A)	biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central		biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central	Agonist activity at PXR (unknown origin) expressed in human HepG2 cells assessed as induction of CYP3A4 transactivation after 16 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assay	biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:Q06432	RO:0002436	drug_central		biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:O60840	RO:0002436	drug_central		biolink:Association
DrugCentral:1937	biolink:molecularly_interacts_with	UniProtKB:Q13698	RO:0002436	drug_central		biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central		biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:O00555	RO:0002436	drug_central		biolink:Association
DrugCentral:1942	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1943	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central		biolink:Association
DrugCentral:1944	biolink:molecularly_interacts_with	UniProtKB:P32754	RO:0002436	drug_central		biolink:Association
DrugCentral:1945	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1945	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:1945	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:O15554	RO:0002436	drug_central		biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human Potassium channel HERG expressed in mammalian cells	biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Recombinant Cav1.3 calcium channel complexes expressed in tsA-cells	biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:Q06432	RO:0002436	drug_central		biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central		biolink:Association
DrugCentral:1947	biolink:molecularly_interacts_with	UniProtKB:O60840	RO:0002436	drug_central		biolink:Association
DrugCentral:1948	biolink:molecularly_interacts_with	UniProtKB:O75343	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1948	biolink:molecularly_interacts_with	UniProtKB:P33402	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1948	biolink:molecularly_interacts_with	UniProtKB:Q02108	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1948	biolink:molecularly_interacts_with	UniProtKB:Q02153	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1949	biolink:molecularly_interacts_with	UniProtKB:P11413	RO:0002436	drug_central		biolink:Association
DrugCentral:1950	biolink:molecularly_interacts_with	UniProtKB:P11413	RO:0002436	drug_central		biolink:Association
DrugCentral:1952	biolink:molecularly_interacts_with	UniProtKB:O75343	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1952	biolink:molecularly_interacts_with	UniProtKB:P33402	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1952	biolink:molecularly_interacts_with	UniProtKB:Q02108	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1952	biolink:molecularly_interacts_with	UniProtKB:Q02153	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:1952	biolink:molecularly_interacts_with	UniProtKB:P16066	RO:0002436	drug_central		biolink:Association
DrugCentral:1954	biolink:molecularly_interacts_with	UniProtKB:P50579	RO:0002436	drug_central	Inhibition of human methionine aminopeptidase 2	biolink:Association
DrugCentral:1954	biolink:molecularly_interacts_with	UniProtKB:P07858	RO:0002436	drug_central	Mixed inhibition of cathepsin B (unknown origin) endopeptidase activity assessed as inhibition constant for enzyme-substrate-inhibitor complex	biolink:Association
DrugCentral:1954	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate assessed as formation of prostanoid products preincubated for 10 mins prior to substrate addition measured after 2 mins by Ellman's method	biolink:Association
DrugCentral:1955	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:1955	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:1958	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Inhibition of human recombinant SERT expressed in HEK cells	biolink:Association
DrugCentral:1958	biolink:molecularly_interacts_with	UniProtKB:P68871	RO:0002436	drug_central		biolink:Association
DrugCentral:1958	biolink:molecularly_interacts_with	UniProtKB:P69905	RO:0002436	drug_central		biolink:Association
DrugCentral:1958	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1958	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1958	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1958	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1958	biolink:molecularly_interacts_with	UniProtKB:P05164	RO:0002436	drug_central		biolink:Association
DrugCentral:1958	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central		biolink:Association
DrugCentral:1959	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1960	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Displacement of [3H]prazosin from human adrenergic Alpha-1B receptor expressed in CHO cell membrane	biolink:Association
DrugCentral:1960	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Binding affinity for human Alpha-2C adrenergic receptor	biolink:Association
DrugCentral:1960	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity to human adrenergic beta2 receptor	biolink:Association
DrugCentral:1960	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:1960	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Binding affinity for human Alpha-2A adrenergic receptor	biolink:Association
DrugCentral:1960	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding affinity against alpha-1 adrenergic receptor in guinea pig cerebral cortical membranes by displacement of [3H]- WB-4101	biolink:Association
DrugCentral:1960	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1960	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:1960	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1960	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1962	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1962	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1962	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1962	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	biolink:Association
DrugCentral:1962	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1962	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1963	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1963	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:1963	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1963	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:1963	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:1963	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	biolink:Association
DrugCentral:1963	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1965	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central	Mechanism of Action; CHEMBL208; SINGLE PROTEIN	biolink:Association
DrugCentral:1967	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:1967	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:1967	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:1967	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:1967	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central		biolink:Association
DrugCentral:1967	biolink:molecularly_interacts_with	UniProtKB:Q02880	RO:0002436	drug_central		biolink:Association
DrugCentral:1967	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central		biolink:Association
DrugCentral:1967	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1968	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation counting	biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P78508	RO:0002436	drug_central	inhibition at +30 mV	biolink:Association
DrugCentral:1971	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central		biolink:Association
DrugCentral:1973	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1973	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1973	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1973	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1974	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central	Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells by Hoechst 33342 assay	biolink:Association
DrugCentral:1976	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	In vitro blocking activity against alpha adrenergic receptor, isolated from rabbit aortic strip	biolink:Association
DrugCentral:1976	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	In vitro blocking activity against alpha adrenergic receptor, isolated from rabbit aortic strip	biolink:Association
DrugCentral:1976	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	In vitro blocking activity against alpha adrenergic receptor, isolated from rabbit aortic strip	biolink:Association
DrugCentral:1980	biolink:molecularly_interacts_with	UniProtKB:P35346	RO:0002436	drug_central		biolink:Association
DrugCentral:1980	biolink:molecularly_interacts_with	UniProtKB:P32745	RO:0002436	drug_central		biolink:Association
DrugCentral:1980	biolink:molecularly_interacts_with	UniProtKB:P30874	RO:0002436	drug_central		biolink:Association
DrugCentral:1980	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:1980	biolink:molecularly_interacts_with	UniProtKB:P30872	RO:0002436	drug_central	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	biolink:Association
DrugCentral:1980	biolink:molecularly_interacts_with	UniProtKB:P31391	RO:0002436	drug_central	Displacement of [125I]-somatostatin from human sst4 receptor after 2 hrs by beta scintillation counting analysis	biolink:Association
DrugCentral:1981	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1981	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:1981	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:1981	biolink:molecularly_interacts_with	UniProtKB:Q9Y5N1	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity to 5HT1A receptor	biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:1982	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:1985	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central		biolink:Association
DrugCentral:1986	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1987	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1987	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:1988	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central	Mechanism of Action; CHEMBL215; SINGLE PROTEIN	biolink:Association
DrugCentral:1988	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Mechanism of Action; CHEMBL235; SINGLE PROTEIN	biolink:Association
DrugCentral:1988	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094253; PROTEIN FAMILY	biolink:Association
DrugCentral:1988	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094253; PROTEIN FAMILY	biolink:Association
DrugCentral:1989	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Inhibition of human somatic ACE C-terminal domain	biolink:Association
DrugCentral:1989	biolink:molecularly_interacts_with	UniProtKB:P08473	RO:0002436	drug_central	Inhibition of human somatic NEP	biolink:Association
DrugCentral:1990	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central		biolink:Association
DrugCentral:1990	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central		biolink:Association
DrugCentral:1990	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:1990	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:1990	biolink:molecularly_interacts_with	UniProtKB:P20648	RO:0002436	drug_central	In vitro inhibitory activity against H+/K+ ATPase prepared from canine fundic mucosa	biolink:Association
DrugCentral:1990	biolink:molecularly_interacts_with	UniProtKB:P51164	RO:0002436	drug_central	In vitro inhibitory activity against H+/K+ ATPase prepared from canine fundic mucosa	biolink:Association
DrugCentral:1990	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:1990	biolink:molecularly_interacts_with	UniProtKB:P49327	RO:0002436	drug_central		biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:O75751	RO:0002436	drug_central	Inhibition of human OCT3-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determined	biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central	In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determined	biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells up to 500 uM after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated [14]-metformin uptake expressed in HEK293 cells after 1.5 mins by scintillation counting analysis	biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:O95264	RO:0002436	drug_central	GRAC: human 5-HT3B selective antagonist	biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:1992	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1993	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central	Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand	biolink:Association
DrugCentral:1993	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand	biolink:Association
DrugCentral:1996	biolink:molecularly_interacts_with	UniProtKB:Q9BV23	RO:0002436	drug_central		biolink:Association
DrugCentral:1996	biolink:molecularly_interacts_with	UniProtKB:P16233	RO:0002436	drug_central		biolink:Association
DrugCentral:1996	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central	Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation counting	biolink:Association
DrugCentral:1996	biolink:molecularly_interacts_with	UniProtKB:Q8N2K0	RO:0002436	drug_central	Inhibition of recombinant ABHD12 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe	biolink:Association
DrugCentral:1996	biolink:molecularly_interacts_with	UniProtKB:Q8NCG7	RO:0002436	drug_central	Inhibition of human recombinant DAGLbeta overexpressed in african green monkey COS7 cells	biolink:Association
DrugCentral:1996	biolink:molecularly_interacts_with	UniProtKB:Q9Y4D2	RO:0002436	drug_central	Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate in detergent free solution by FRET assay	biolink:Association
DrugCentral:1996	biolink:molecularly_interacts_with	UniProtKB:O95870	RO:0002436	drug_central	Inhibition of recombinant BAT5 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe	biolink:Association
DrugCentral:1996	biolink:molecularly_interacts_with	UniProtKB:Q13093	RO:0002436	drug_central	Inhibition of recombinant PLA2g7 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe	biolink:Association
DrugCentral:1996	biolink:molecularly_interacts_with	UniProtKB:P07098	RO:0002436	drug_central	Mechanism of Action; CHEMBL1796; SINGLE PROTEIN	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central		biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central		biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central		biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:O60391	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:1999	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:2002	biolink:molecularly_interacts_with	UniProtKB:P11172	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2004	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central		biolink:Association
DrugCentral:2004	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2004	biolink:molecularly_interacts_with	UniProtKB:P40763	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Dose response cell-based assay to measure STAT3 inhibition. (Class of assay: confirmatory) [Related pubchem assays: 920, 1317, 1265, 1308, 862 ]	biolink:Association
DrugCentral:2006	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2006	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2006	biolink:molecularly_interacts_with	UniProtKB:Q9HCR9	RO:0002436	drug_central		biolink:Association
DrugCentral:2008	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 production	biolink:Association
DrugCentral:2011	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:2013	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:2013	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2013	biolink:molecularly_interacts_with	UniProtKB:P21462	RO:0002436	drug_central		biolink:Association
DrugCentral:2014	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2014	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2014	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2014	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2014	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2015	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2015	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2015	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2017	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:2026	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Mechanism of Action; CHEMBL245; SINGLE PROTEIN	biolink:Association
DrugCentral:2026	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Mechanism of Action; CHEMBL216; SINGLE PROTEIN	biolink:Association
DrugCentral:2027	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2027	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2027	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells	biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells	biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells	biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	Displacement of [3H]N-methylscopolamine from human muscarinic M4 receptor expressed in CHO cells after 120 mins by scintillation counting	biolink:Association
DrugCentral:2028	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	Displacement of [3H]N-methylscopolamine from human muscarinic M5 receptor expressed in CHO cells after 120 mins by scintillation counting	biolink:Association
DrugCentral:2029	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assay	biolink:Association
DrugCentral:2029	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assay	biolink:Association
DrugCentral:2029	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Displacement of [125I]Clonidine from adrenergic alpha2C receptor (unknown origin)	biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central	Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2AR	biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 1B receptor using [3H]5-HT trifluoroacetate as radioligand	biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 1D receptor using [3H]5-HT trifluoroacetate as radioligand	biolink:Association
DrugCentral:2032	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Displacement of [125I]Clonidine from adrenergic alpha2A receptor (unknown origin)	biolink:Association
DrugCentral:2033	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:2033	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:2034	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:2034	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Inhibitory binding constant in guinea pig brain homogenate was reported at Opioid receptor delta 1 at a a temperature 25 degree Celsius labeled with [3H](D-Ala2-D-Leu5)-enkephalin (0.7 nM)	biolink:Association
DrugCentral:2034	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:2036	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094253; PROTEIN FAMILY	biolink:Association
DrugCentral:2036	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094253; PROTEIN FAMILY	biolink:Association
DrugCentral:2036	biolink:molecularly_interacts_with	UniProtKB:Q16647	RO:0002436	drug_central		biolink:Association
DrugCentral:2036	biolink:molecularly_interacts_with	UniProtKB:P21462	RO:0002436	drug_central		biolink:Association
DrugCentral:2039	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2039	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Mechanism of Action; CHEMBL245; SINGLE PROTEIN	biolink:Association
DrugCentral:2042	biolink:molecularly_interacts_with	UniProtKB:P01178	RO:0002436	drug_central		biolink:Association
DrugCentral:2042	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central		biolink:Association
DrugCentral:2042	biolink:molecularly_interacts_with	UniProtKB:P47901	RO:0002436	drug_central		biolink:Association
DrugCentral:2042	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central		biolink:Association
DrugCentral:2042	biolink:molecularly_interacts_with	UniProtKB:P30559	RO:0002436	drug_central	Binding affinity for human oxytocin receptor	biolink:Association
DrugCentral:2043	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	Inhibitory activity against human thromboxane synthetase	biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P32238	RO:0002436	drug_central	DRUGMATRIX: Cholecystokinin CCKA radioligand binding (ligand: [3H] L-364,718)	biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:Q5T3U5	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central		biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of MDR1 (unknown origin) transfected in human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay	biolink:Association
DrugCentral:2044	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assay	biolink:Association
DrugCentral:2045	biolink:molecularly_interacts_with	UniProtKB:P34972	RO:0002436	drug_central		biolink:Association
DrugCentral:2045	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central		biolink:Association
DrugCentral:2045	biolink:molecularly_interacts_with	UniProtKB:Q9Y2T6	RO:0002436	drug_central		biolink:Association
DrugCentral:2046	biolink:molecularly_interacts_with	UniProtKB:O95264	RO:0002436	drug_central	Binding affinity to human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysis	biolink:Association
DrugCentral:2046	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Binding affinity to human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysis	biolink:Association
DrugCentral:2046	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Binding affinity to 5HT3A receptor	biolink:Association
DrugCentral:2048	biolink:molecularly_interacts_with	UniProtKB:P14324	RO:0002436	drug_central	Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 mins	biolink:Association
DrugCentral:2049	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human cytosolic carbonic anhydrase 1 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:2049	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human cytosolic carbonic anhydrase 2 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:2050	biolink:molecularly_interacts_with	UniProtKB:P18031	RO:0002436	drug_central	Dissociation constant for Protein-tyrosine phosphatase 1B	biolink:Association
DrugCentral:2050	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094253; PROTEIN FAMILY	biolink:Association
DrugCentral:2050	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094253; PROTEIN FAMILY	biolink:Association
DrugCentral:2052	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:2052	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:2052	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:2052	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:2052	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:2052	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2052	biolink:molecularly_interacts_with	UniProtKB:P07510	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2052	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2052	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2054	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2054	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells up to 500 uM after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2054	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated [14]-metformin uptake expressed in polarized MDCK2 cells after 5 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:2054	biolink:molecularly_interacts_with	UniProtKB:P20648	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095173; PROTEIN COMPLEX	biolink:Association
DrugCentral:2054	biolink:molecularly_interacts_with	UniProtKB:P51164	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095173; PROTEIN COMPLEX	biolink:Association
DrugCentral:2054	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central		biolink:Association
DrugCentral:2054	biolink:molecularly_interacts_with	UniProtKB:P49327	RO:0002436	drug_central		biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP)	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central		biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central	Inhibitory activity against cyclic GMP-phosphodiesterase (PDE V) isolated from porcine aorta.	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Inhibition of human recombinant PDE3B transfected in Sf9 cells by SPA	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of AChE activity	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Inhibition of human recombinant PDE3A transfected in Sf9 cells by SPA	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:O00408	RO:0002436	drug_central	Inhibition of cGMP-stimulated phosphodiesterase 2 of porcine coronary arteries	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:P54750	RO:0002436	drug_central	Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of human lung	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:Q01064	RO:0002436	drug_central	Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of human lung	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:Q14123	RO:0002436	drug_central	Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of human lung	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:Q9Y233	RO:0002436	drug_central	Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assay	biolink:Association
DrugCentral:2056	biolink:molecularly_interacts_with	UniProtKB:Q9UM07	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Fluorescence-based biochemical dose response assay to identify inhibitors of Protein Arginine Deaminase 4 (PAD4). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463073, AID463083, AID485272, AID488796]	biolink:Association
DrugCentral:2059	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362995; PROTEIN FAMILY	biolink:Association
DrugCentral:2059	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362995; PROTEIN FAMILY	biolink:Association
DrugCentral:2059	biolink:molecularly_interacts_with	UniProtKB:Q9P0X4	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362995; PROTEIN FAMILY	biolink:Association
DrugCentral:2063	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	recombinant human cyclooxygenase	biolink:Association
DrugCentral:2063	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	recombinant human cyclooxygenase	biolink:Association
DrugCentral:2065	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Inhibition constant against human recombinant Monoamine oxidase-B 	biolink:Association
DrugCentral:2065	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of MAOA (unknown origin) using kynuramine as substrate after 1 hr by fluorescence assay	biolink:Association
DrugCentral:2066	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central		biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central		biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity to 5HT1A receptor	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:Q99571	RO:0002436	drug_central	Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubated for 30 mins followed by ATP addition by Fluo-4 AM dye-based fluorescence assay	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Binding inhibition towards human serotonin transporter	biolink:Association
DrugCentral:2068	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	Displacement of [125I]substance P from human recombinant NK1 receptor expressed in human U373 cells after 1 hr by scintillation counting analysis	biolink:Association
DrugCentral:2071	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central		biolink:Association
DrugCentral:2073	biolink:molecularly_interacts_with	UniProtKB:P15328	RO:0002436	drug_central		biolink:Association
DrugCentral:2073	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central		biolink:Association
DrugCentral:2073	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central		biolink:Association
DrugCentral:2073	biolink:molecularly_interacts_with	UniProtKB:Q05932	RO:0002436	drug_central		biolink:Association
DrugCentral:2073	biolink:molecularly_interacts_with	UniProtKB:P34896	RO:0002436	drug_central	Binding affinity to human recombinant Serine hydroxymethyltransferase, cytosolic by isothermal titration calorimetry	biolink:Association
DrugCentral:2073	biolink:molecularly_interacts_with	UniProtKB:Q96NT5	RO:0002436	drug_central	Inhibition of [3H]MTX transport at human PCFT expressed in Chinese hamster R2 cells at pH 5.5 by Dixon plot	biolink:Association
DrugCentral:2073	biolink:molecularly_interacts_with	UniProtKB:P22102	RO:0002436	drug_central	Inhibition of GARFT	biolink:Association
DrugCentral:2073	biolink:molecularly_interacts_with	UniProtKB:P41440	RO:0002436	drug_central		biolink:Association
DrugCentral:2073	biolink:molecularly_interacts_with	UniProtKB:P14207	RO:0002436	drug_central		biolink:Association
DrugCentral:2075	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2078	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2078	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2078	biolink:molecularly_interacts_with	UniProtKB:P02763	RO:0002436	drug_central		biolink:Association
DrugCentral:2078	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2080	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2088	biolink:molecularly_interacts_with	UniProtKB:P32239	RO:0002436	drug_central	Inhibition of binding of [125I]-PD 142308 to CCK-B receptor was determined	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:O75751	RO:0002436	drug_central	Inhibition of human OCT3-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:O75365	RO:0002436	drug_central	Inhibition of human recombinant PRL-3	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of human OCT1-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P07477	RO:0002436	drug_central	Inhibition of trypsin by amidase assay.	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Antagonist activity at NR1/NR2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at pH 7.6 at -40mV holding potential by two-electrode voltage-clamp electrophysiology	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	Antagonist activity at NR1/NR2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at pH 7.6 at -40mV holding potential by two-electrode voltage-clamp electrophysiology	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P19801	RO:0002436	drug_central	Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cells	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y6	RO:0002436	drug_central	compound was tested for inhibitory activity against Matriptase	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P04271	RO:0002436	drug_central	Binding to holo-S100B protein	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells up to 500 uM after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated [14]-metformin uptake expressed in polarized MDCK2 cells after 5 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:2090	biolink:molecularly_interacts_with	UniProtKB:P21673	RO:0002436	drug_central	Inhibition of human SSAT using spermidine as substrate	biolink:Association
DrugCentral:2095	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Displacement of [3H]R-(-)-14 from human FLAG-tagged beta3 GABA A receptor expressed in HEK293S cells	biolink:Association
DrugCentral:2095	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2095	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2095	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2095	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2095	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:2095	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:2095	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:2096	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central	Mechanism of Action; CHEMBL1907594; PROTEIN COMPLEX	biolink:Association
DrugCentral:2096	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central	Mechanism of Action; CHEMBL1907594; PROTEIN COMPLEX	biolink:Association
DrugCentral:2096	biolink:molecularly_interacts_with	UniProtKB:Q9GZZ6	RO:0002436	drug_central		biolink:Association
DrugCentral:2098	biolink:molecularly_interacts_with	UniProtKB:P00813	RO:0002436	drug_central		biolink:Association
DrugCentral:2099	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central		biolink:Association
DrugCentral:2099	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central		biolink:Association
DrugCentral:2099	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central	Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligand	biolink:Association
DrugCentral:2099	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human AChE using acetylthiocholine iodide as substrate treated 5 mins before substrate addition measured up to 4 mins by Ellman's method	biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2105	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human Potassium channel HERG expressed in mammalian cells	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:P23786	RO:0002436	drug_central	Inhibition of human CPT2	biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:P50416	RO:0002436	drug_central		biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:Q9P0X4	RO:0002436	drug_central		biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:2106	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central		biolink:Association
DrugCentral:2108	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Inhibition of ACE (unknown origin)	biolink:Association
DrugCentral:2111	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2111	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2111	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2111	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2111	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2111	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:2112	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2112	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2112	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2113	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2114	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:2115	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2119	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Displacement of [3H]U69593 form human kappa opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:2119	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Displacement of [3H]Naltrindole form human delta opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:2119	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Displacement of [3H]DAMGO form human mu opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:2120	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:2120	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:2120	biolink:molecularly_interacts_with	UniProtKB:Q01118	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:2120	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:2120	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:2120	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:2120	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:2120	biolink:molecularly_interacts_with	UniProtKB:Q9UI33	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:2120	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:2120	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:P42785	RO:0002436	drug_central	Inhibition of [3H]-TCP binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellum	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Compound was evaluated for its ability to displace [3H](+)-pentazocine from sigma receptor in Guinea pig brain	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assay	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assay	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assay	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assay	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central	Affinity to NMDA receptor, using [3H]MK-801 as radioligand in pig brain cortex membranes	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:O60391	RO:0002436	drug_central	Affinity to NMDA receptor, using [3H]MK-801 as radioligand in pig brain cortex membranes	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Affinity to NMDA receptor, using [3H]MK-801 as radioligand in pig brain cortex membranes	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	Affinity to NMDA receptor, using [3H]MK-801 as radioligand in pig brain cortex membranes	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	Affinity to NMDA receptor, using [3H]MK-801 as radioligand in pig brain cortex membranes	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central	Affinity to NMDA receptor, using [3H]MK-801 as radioligand in pig brain cortex membranes	biolink:Association
DrugCentral:2121	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central	Affinity to NMDA receptor, using [3H]MK-801 as radioligand in pig brain cortex membranes	biolink:Association
DrugCentral:2122	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity to 5HT1A receptor	biolink:Association
DrugCentral:2122	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Mechanism of Action; CHEMBL238; SINGLE PROTEIN	biolink:Association
DrugCentral:2122	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Mechanism of Action; CHEMBL222; SINGLE PROTEIN	biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:Q16853	RO:0002436	drug_central	Inhibition of human recombinant VAP-1 expressed in CHO cells after 30 mins by coupled colorimetric method	biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:O60341	RO:0002436	drug_central	Inhibition of LSD1	biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central		biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central		biolink:Association
DrugCentral:2123	biolink:molecularly_interacts_with	UniProtKB:P10632	RO:0002436	drug_central		biolink:Association
DrugCentral:2126	biolink:molecularly_interacts_with	UniProtKB:Q9Y478	RO:0002436	drug_central		biolink:Association
DrugCentral:2130	biolink:molecularly_interacts_with	UniProtKB:Q9BQB6	RO:0002436	drug_central		biolink:Association
DrugCentral:2130	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central		biolink:Association
DrugCentral:2131	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2131	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2132	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:2132	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2132	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2132	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2132	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action; CHEMBL231; SINGLE PROTEIN	biolink:Association
DrugCentral:2133	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2133	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2133	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central		biolink:Association
DrugCentral:2134	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2134	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2134	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2134	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:2134	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:2135	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central	Inhibition of human thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assay	biolink:Association
DrugCentral:2136	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2136	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2136	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2136	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2136	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2136	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2136	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2138	biolink:molecularly_interacts_with	UniProtKB:Q9BQB6	RO:0002436	drug_central		biolink:Association
DrugCentral:2139	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362995; PROTEIN FAMILY	biolink:Association
DrugCentral:2139	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362995; PROTEIN FAMILY	biolink:Association
DrugCentral:2139	biolink:molecularly_interacts_with	UniProtKB:Q9P0X4	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362995; PROTEIN FAMILY	biolink:Association
DrugCentral:2140	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2140	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Binding affinity towards human alpha-1B adrenergic receptor expressed in Chinese Hamster ovary (CHO) cells	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	The compound was tested for affinity towards sigma-3 receptor	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Binding affinity against Alpha-2B adrenergic receptor from human clones.	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Binding affinity against Alpha-2C adrenergic receptor from human clones.	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Binding affinity towards human alpha-1D adrenergic receptor expressed in Chinese Hamster ovary (CHO) cells	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central	Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2AR	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Displacement of [3H]RX781094 from alpha2 adrenergic receptor	biolink:Association
DrugCentral:2142	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding affinity towards alpha-1A adrenergic receptor expressed in human embryonic kidney (HEK293) cells	biolink:Association
DrugCentral:2145	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Compound was evaluated for inhibition of Prostaglandin G/H synthase 1	biolink:Association
DrugCentral:2145	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:2145	biolink:molecularly_interacts_with	UniProtKB:Q16647	RO:0002436	drug_central		biolink:Association
DrugCentral:2145	biolink:molecularly_interacts_with	UniProtKB:P21462	RO:0002436	drug_central		biolink:Association
DrugCentral:2146	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2146	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:2146	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Compound was tested for its ability to displace [3H]clonidine form alpha-2 adrenergic receptor site in guinea pig cerebral cortical membranes.	biolink:Association
DrugCentral:2146	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Compound was tested for its ability to displace [3H]clonidine form alpha-2 adrenergic receptor site in guinea pig cerebral cortical membranes.	biolink:Association
DrugCentral:2146	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Compound was tested for its ability to displace [3H]clonidine form alpha-2 adrenergic receptor site in guinea pig cerebral cortical membranes.	biolink:Association
DrugCentral:2146	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2149	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Mechanism of Action; CHEMBL229; SINGLE PROTEIN	biolink:Association
DrugCentral:2149	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2149	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2149	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2149	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2149	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2149	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2149	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2149	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2150	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity for human recombinant dopamine receptor D2L	biolink:Association
DrugCentral:2150	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central	Binding affinity for human recombinant dopamine receptor D5	biolink:Association
DrugCentral:2150	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Binding affinity for human recombinant dopamine receptor D1	biolink:Association
DrugCentral:2150	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding affinity for human recombinant dopamine receptor D4.4	biolink:Association
DrugCentral:2150	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2152	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2152	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2152	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2152	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2152	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central		biolink:Association
DrugCentral:2152	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Affinity for inactive human SkM1 sodium channel expressed in HEK293 cells	biolink:Association
DrugCentral:2152	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:2152	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:2153	biolink:molecularly_interacts_with	UniProtKB:P56817	RO:0002436	drug_central	Inhibition of human recombinant BACE1 after 60 mins by FRET assay	biolink:Association
DrugCentral:2156	biolink:molecularly_interacts_with	UniProtKB:P54750	RO:0002436	drug_central	Binding affinity for [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of human brain	biolink:Association
DrugCentral:2156	biolink:molecularly_interacts_with	UniProtKB:Q01064	RO:0002436	drug_central	Binding affinity for [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of human brain	biolink:Association
DrugCentral:2156	biolink:molecularly_interacts_with	UniProtKB:Q14123	RO:0002436	drug_central	Binding affinity for [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of human brain	biolink:Association
DrugCentral:2156	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Binding affinity for low Km cAMP phosphodiesterase PDE III of human platelets	biolink:Association
DrugCentral:2156	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Binding affinity for low Km cAMP phosphodiesterase PDE III of human platelets	biolink:Association
DrugCentral:2159	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2159	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	In vitro inhibitory activity against acetylcholinesterase	biolink:Association
DrugCentral:2159	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central	Inhibition of anticholinesterase activity by their ability to inactivate human serum butyrylcholinesterase	biolink:Association
DrugCentral:2162	biolink:molecularly_interacts_with	UniProtKB:P48167	RO:0002436	drug_central		biolink:Association
DrugCentral:2162	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:2162	biolink:molecularly_interacts_with	UniProtKB:P23416	RO:0002436	drug_central		biolink:Association
DrugCentral:2163	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central	GRAC: human Glycine receptor subunit alpha-1 channel blocker	biolink:Association
DrugCentral:2163	biolink:molecularly_interacts_with	UniProtKB:O75311	RO:0002436	drug_central	GRAC: human Glycine receptor subunit alpha-3 channel blocker	biolink:Association
DrugCentral:2163	biolink:molecularly_interacts_with	UniProtKB:P48167	RO:0002436	drug_central		biolink:Association
DrugCentral:2163	biolink:molecularly_interacts_with	UniProtKB:P23416	RO:0002436	drug_central		biolink:Association
DrugCentral:2165	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2165	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2166	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	calcium response in CHO cells	biolink:Association
DrugCentral:2166	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	calcium response in CHO cells	biolink:Association
DrugCentral:2166	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	calcium response in CHO cells	biolink:Association
DrugCentral:2166	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	calcium response in CHO cells	biolink:Association
DrugCentral:2166	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	calcium response in CHO cells	biolink:Association
DrugCentral:2167	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG channel in HEK293 cells by voltage-clamp method	biolink:Association
DrugCentral:2167	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	pH 8.2; use-dependent block at -70mV	biolink:Association
DrugCentral:2168	biolink:molecularly_interacts_with	UniProtKB:P62942	RO:0002436	drug_central		biolink:Association
DrugCentral:2168	biolink:molecularly_interacts_with	UniProtKB:P48454	RO:0002436	drug_central		biolink:Association
DrugCentral:2168	biolink:molecularly_interacts_with	UniProtKB:P60568	RO:0002436	drug_central		biolink:Association
DrugCentral:2168	biolink:molecularly_interacts_with	UniProtKB:P01579	RO:0002436	drug_central		biolink:Association
DrugCentral:2168	biolink:molecularly_interacts_with	UniProtKB:P05113	RO:0002436	drug_central		biolink:Association
DrugCentral:2171	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Inhibition of phosphodiesterase 3	biolink:Association
DrugCentral:2171	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Inhibition of phosphodiesterase 3	biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:O94782	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:Q9P0X4	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:Q16322	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P0DP23	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P0DP24	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P0DP25	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central	Inhibition of T-type alpha1G calcium channel	biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligand	biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Binding affinity against delta opiate receptor using [3H]DPDPE	biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Binding affinity against mu opioid receptor using [3H]DAMGO	biolink:Association
DrugCentral:2172	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:2173	biolink:molecularly_interacts_with	UniProtKB:O60706	RO:0002436	drug_central	Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR	biolink:Association
DrugCentral:2173	biolink:molecularly_interacts_with	UniProtKB:O60706	RO:0002436	drug_central	Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranes	biolink:Association
DrugCentral:2173	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranes	biolink:Association
DrugCentral:2173	biolink:molecularly_interacts_with	UniProtKB:Q12791	RO:0002436	drug_central		biolink:Association
DrugCentral:2176	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2176	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2176	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2176	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Evaluated for the binding affinity to porcine choroid plexus at 5-hydroxytryptamine 2C receptor binding site by using [3H]-MES as a radioligand.	biolink:Association
DrugCentral:2176	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	Displacement of [3H]-CGP 12177 from human beta-3 adrenergic receptor expressed in CHOK1 cells	biolink:Association
DrugCentral:2176	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2176	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2176	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2176	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2179	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central		biolink:Association
DrugCentral:2179	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA))	biolink:Association
DrugCentral:2179	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:2179	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Competitive inhibition of human MAOB expressed in Pichia pastoris	biolink:Association
DrugCentral:2179	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	In vitro transactivation of human Peroxisome proliferator activated receptor alpha (hPPARalpha)	biolink:Association
DrugCentral:2179	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2180	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2181	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2183	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:2183	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:2183	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:2183	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:2183	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:2183	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:2183	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:2183	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:2183	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:2193	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2193	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2199	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2200	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2200	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2200	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2200	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2200	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:2200	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Displacement of [3H]N-methylscopolamine chloride from human cloned muscarinic M2 receptor expressed in CHOK1 cells	biolink:Association
DrugCentral:2201	biolink:molecularly_interacts_with	UniProtKB:Q13621	RO:0002436	drug_central		biolink:Association
DrugCentral:2201	biolink:molecularly_interacts_with	UniProtKB:P55011	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2202	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2206	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Monoamine oxidase A (human liver form) inhibitor induced spectral changes	biolink:Association
DrugCentral:2207	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:2210	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2210	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2213	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2213	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2214	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central		biolink:Association
DrugCentral:2220	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2220	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity to dopamine D2 receptor (unknown origin)	biolink:Association
DrugCentral:2220	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation counting analysis	biolink:Association
DrugCentral:2220	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Binding affinity to 5-HT2C receptor (unknown origin)	biolink:Association
DrugCentral:2220	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293 cells by liquid scintillation counting analysis	biolink:Association
DrugCentral:2220	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Binding affinity to 5-HT2A receptor (unknown origin)	biolink:Association
DrugCentral:2220	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Binding affinity to muscarinic M1 receptor (unknown origin)	biolink:Association
DrugCentral:2228	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central		biolink:Association
DrugCentral:2231	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Binding affinity to sarin-inhibited hemoglobin free human erythrocyte ghost acetylcholinesterase using acetylthiocholineiodide as substrate measured up to 1 hr by Ellman method	biolink:Association
DrugCentral:2232	biolink:molecularly_interacts_with	UniProtKB:Q92847	RO:0002436	drug_central		biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	in vitro high binding affinity was determined on human Dopamine receptor D4 expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radioligand.	biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:2233	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2236	biolink:molecularly_interacts_with	UniProtKB:O60894	RO:0002436	drug_central	HEK293S cells	biolink:Association
DrugCentral:2236	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	HEK293S cells	biolink:Association
DrugCentral:2236	biolink:molecularly_interacts_with	UniProtKB:O60896	RO:0002436	drug_central	HEK293S cells	biolink:Association
DrugCentral:2236	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	HEK293S cells	biolink:Association
DrugCentral:2236	biolink:molecularly_interacts_with	UniProtKB:O60895	RO:0002436	drug_central	HEK293S cells	biolink:Association
DrugCentral:2236	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	HEK293S cells	biolink:Association
DrugCentral:2237	biolink:molecularly_interacts_with	UniProtKB:Q9Y271	RO:0002436	drug_central		biolink:Association
DrugCentral:2237	biolink:molecularly_interacts_with	UniProtKB:Q9NS75	RO:0002436	drug_central		biolink:Association
DrugCentral:2237	biolink:molecularly_interacts_with	UniProtKB:Q13304	RO:0002436	drug_central	Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assay	biolink:Association
DrugCentral:2239	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central	Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.	biolink:Association
DrugCentral:2240	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2240	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2240	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2241	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:2243	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:2245	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:2245	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:2245	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central	Displacement of [3H]-aldosterone from human mineralocorticoid receptor expressed in HEK293 cells	biolink:Association
DrugCentral:2245	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Displacement of [3H]-methyltrienolone from human androgen receptor expressed in HEK293 cells	biolink:Association
DrugCentral:2245	biolink:molecularly_interacts_with	UniProtKB:P15104	RO:0002436	drug_central	Ability to induce human glutamine synthetase in skeletal muscle cells	biolink:Association
DrugCentral:2245	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:2245	biolink:molecularly_interacts_with	UniProtKB:P05231	RO:0002436	drug_central		biolink:Association
DrugCentral:2247	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:2251	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	BindingDB_Patents: Fluorescence Polarization Ligand Binding Assay. The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-length glucocorticoid (GR) protein. Reagents for this assay are purchased from Invitrogen in a test kit. A fluorescent labeled GR ligand is used as a fluorescent tracer and test compounds compete with the fluorescent tracer for GR binding. The change in polarization value in the presence of test compounds is due to binding of test compounds to GR and is used to determine IC50 and relative binding affinity of test compounds for GR.	biolink:Association
DrugCentral:2251	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Displacement of [3H]-methyltrienolone from human androgen receptor expressed in HEK293 cells	biolink:Association
DrugCentral:2251	biolink:molecularly_interacts_with	UniProtKB:P15104	RO:0002436	drug_central	Ability to induce human glutamine synthetase in skeletal muscle cells	biolink:Association
DrugCentral:2251	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central	Binding affinity to human CBG receptor (corticosteroid-binding globulins)	biolink:Association
DrugCentral:2251	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central	Displacement of [3H]-aldosterone from human mineralocorticoid receptor expressed in HEK293 cells	biolink:Association
DrugCentral:2253	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:2253	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:2253	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:2255	biolink:molecularly_interacts_with	UniProtKB:P54289	RO:0002436	drug_central		biolink:Association
DrugCentral:2255	biolink:molecularly_interacts_with	UniProtKB:Q01650	RO:0002436	drug_central		biolink:Association
DrugCentral:2255	biolink:molecularly_interacts_with	UniProtKB:Q9NY47	RO:0002436	drug_central		biolink:Association
DrugCentral:2256	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:2256	biolink:molecularly_interacts_with	UniProtKB:P11413	RO:0002436	drug_central	Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 mins by Amplite fluorimetric assay	biolink:Association
DrugCentral:2256	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:2258	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2261	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2261	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2261	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2263	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2263	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2263	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2263	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2263	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2265	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2265	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2265	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2266	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2266	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2266	biolink:molecularly_interacts_with	UniProtKB:P16083	RO:0002436	drug_central	Inhibition of human recombinant NQO2	biolink:Association
DrugCentral:2266	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of human recombinant MAOA assessed as conversion of kynuramine to 4-hydroxyquinoline preincubated for 15 mins by fluorimetric assay	biolink:Association
DrugCentral:2266	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Inhibition of human recombinant MAOB assessed as conversion of kynuramine to 4-hydroxyquinoline preincubated for 15 mins by fluorimetric assay	biolink:Association
DrugCentral:2266	biolink:molecularly_interacts_with	UniProtKB:P07900	RO:0002436	drug_central		biolink:Association
DrugCentral:2266	biolink:molecularly_interacts_with	UniProtKB:P69905	RO:0002436	drug_central		biolink:Association
DrugCentral:2266	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2266	biolink:molecularly_interacts_with	UniProtKB:P35869	RO:0002436	drug_central		biolink:Association
DrugCentral:2266	biolink:molecularly_interacts_with	UniProtKB:P11413	RO:0002436	drug_central		biolink:Association
DrugCentral:2267	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2267	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2267	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2268	biolink:molecularly_interacts_with	UniProtKB:Q8TCC7	RO:0002436	drug_central		biolink:Association
DrugCentral:2268	biolink:molecularly_interacts_with	UniProtKB:Q9NSA0	RO:0002436	drug_central		biolink:Association
DrugCentral:2268	biolink:molecularly_interacts_with	UniProtKB:Q96S37	RO:0002436	drug_central	Inhibition of human URAT1-mediated urate uptake in HEK293 cells	biolink:Association
DrugCentral:2268	biolink:molecularly_interacts_with	UniProtKB:Q9HAW7	RO:0002436	drug_central	Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A7	biolink:Association
DrugCentral:2268	biolink:molecularly_interacts_with	UniProtKB:Q4U2R8	RO:0002436	drug_central		biolink:Association
DrugCentral:2268	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central		biolink:Association
DrugCentral:2268	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central		biolink:Association
DrugCentral:2268	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:2269	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2269	biolink:molecularly_interacts_with	UniProtKB:P16050	RO:0002436	drug_central	Inhibition of 15-lipoxygenase by LMB assay	biolink:Association
DrugCentral:2269	biolink:molecularly_interacts_with	UniProtKB:O95477	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362986; SINGLE PROTEIN	biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central		biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q9UBC3	RO:0002436	drug_central		biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q9Y6K1	RO:0002436	drug_central		biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:P26358	RO:0002436	drug_central		biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q01118	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q9UI33	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2270	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2271	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central		biolink:Association
DrugCentral:2271	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:2271	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:2271	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:2271	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:2271	biolink:molecularly_interacts_with	UniProtKB:P21817	RO:0002436	drug_central		biolink:Association
DrugCentral:2271	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:2273	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2274	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:O15399	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:O60391	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:Q14957	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:2276	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central	The compound was tested for its ability to block PCP N-methyl-D-aspartate glutamate receptor at the PCP (phencyclidine) binding site in postmortem human frontal cortex.	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2278	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Displacement of [3H]gamma-amino butyric acid from Gamma-aminobutyric acid (GABA-A) receptor of human cerebellar cortex preparation	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of P-glycoprotein expressed in A2780/ADR cells by calcein AM assay	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Displacement of Dexamethasone from human glucocorticoid receptor expressed in baculovirus SF-12 cells	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:P35610	RO:0002436	drug_central	In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Displacement of DHT from human androgen receptor expressed in baculovirus SF-12 cells	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:P12104	RO:0002436	drug_central	Displacement of 1-anilinonaphthalene-8-sulphonic acid from I-FABP	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:Q9UL62	RO:0002436	drug_central		biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:Q8NEC5	RO:0002436	drug_central	Patch clamp electrophysiology, kinetic rapid mixing fluorometry,  2-3  &micro;M shows the saturating efficacy.	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:Q7RTX7	RO:0002436	drug_central	Patch clamp electrophysiology, kinetic rapid mixing fluorometry, 2-3&micro;M shows the saturating efficacy.	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:Q96P56	RO:0002436	drug_central	Patch clamp electrophysiology, kinetic rapid mixing fluorometry; 2-3  &micro;M shows the saturating efficacy.	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:Q86XQ3	RO:0002436	drug_central	Patch clamp electrophysiology, kinetic rapid mixing fluorometry, 2-3&micro;M shows the saturating efficacy.	biolink:Association
DrugCentral:2279	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:2281	biolink:molecularly_interacts_with	UniProtKB:P32239	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P04156	RO:0002436	drug_central	Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cells	biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2284	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:2285	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central	Binding affinity to progesterone receptor	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P04156	RO:0002436	drug_central	Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cells	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Binding affinity to SERT (unknown origin) by radioligand binding assay	biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central		biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:2286	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central		biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:Q8IWT1	RO:0002436	drug_central		biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:Q9NY72	RO:0002436	drug_central		biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:Q07699	RO:0002436	drug_central		biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Inhibition of human cloned Nav1.5 channel expressed in chinese hamster CHO cells assessed as tonic inhibition after 5 mins by patch clamp assay	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:O60706	RO:0002436	drug_central	Inhibition of human kir6.2/SUR2A ion channel coexpressed in human HEK293 cells after 5 mins by patch clamp assay	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	Inhibition of human kir6.2/SUR2A ion channel coexpressed in human HEK293 cells after 5 mins by patch clamp assay	biolink:Association
DrugCentral:2291	biolink:molecularly_interacts_with	UniProtKB:O60939	RO:0002436	drug_central		biolink:Association
DrugCentral:2293	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2293	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2293	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2293	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2294	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central		biolink:Association
DrugCentral:2294	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2294	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:2294	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2294	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2294	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2296	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human AChE using acetylthiocholine iodide as substrate treated 5 mins before substrate addition measured up to 4 mins by Ellman's method	biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2298	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2299	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	GABA-modulatory action compound was evaluated on Oocytes expressing recombinant human alpha-1-beta-3-gamma-2L GABA A receptor at concentrations of >=100 micro<M	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	GABA-modulatory action compound was evaluated on Oocytes expressing recombinant human alpha-1-beta-3-gamma-2L GABA A receptor at concentrations of >=100 micro<M	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	GABA-modulatory action compound was evaluated on Oocytes expressing recombinant human alpha-1-beta-3-gamma-2L GABA A receptor at concentrations of >=100 micro<M	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expressed in Xenopus oocytes	biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central		biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:2302	biolink:molecularly_interacts_with	UniProtKB:O00519	RO:0002436	drug_central		biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity model	biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:2303	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2308	biolink:molecularly_interacts_with	UniProtKB:P07202	RO:0002436	drug_central		biolink:Association
DrugCentral:2308	biolink:molecularly_interacts_with	UniProtKB:P49895	RO:0002436	drug_central	Mechanism of Action; CHEMBL2019; SINGLE PROTEIN	biolink:Association
DrugCentral:2308	biolink:molecularly_interacts_with	UniProtKB:P05164	RO:0002436	drug_central		biolink:Association
DrugCentral:2309	biolink:molecularly_interacts_with	UniProtKB:O75762	RO:0002436	drug_central	inhibition of calcium response evoked by the TRPA1 agonist AITC (10uM) in IMR90	biolink:Association
DrugCentral:2311	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2311	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2313	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central		biolink:Association
DrugCentral:2316	biolink:molecularly_interacts_with	UniProtKB:P34981	RO:0002436	drug_central	Displacement of [3H]N(1)-Me-His-TRH from TRHR1	biolink:Association
DrugCentral:2318	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Mechanism of Action; CHEMBL210; SINGLE PROTEIN	biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2320	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2326	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Mechanism of Action; CHEMBL222; SINGLE PROTEIN	biolink:Association
DrugCentral:2326	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2326	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2326	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2328	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:2328	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:2328	biolink:molecularly_interacts_with	UniProtKB:P20815	RO:0002436	drug_central		biolink:Association
DrugCentral:2330	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman technique	biolink:Association
DrugCentral:2330	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central	Inhibition of anticholinesterase activity by their ability to inactivate human serum butyrylcholinesterase	biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against IKr potassium channel	biolink:Association
DrugCentral:2331	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	GRAC: human H1 selective antagonist	biolink:Association
DrugCentral:2332	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2332	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central	Cytotoxicity by selective inhibition against human dihydrofolate reductase (DHFR).	biolink:Association
DrugCentral:2332	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:2332	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central		biolink:Association
DrugCentral:2336	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central		biolink:Association
DrugCentral:2336	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2336	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:2336	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central		biolink:Association
DrugCentral:2336	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2336	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:2336	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2336	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central		biolink:Association
DrugCentral:2336	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Binding affinity towards human M1 receptor.	biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Binding affinity to human cloned 5HT6 receptor	biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Binding affinity against dopamine receptor D1	biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding affinity towards human dopamine-4.2 receptor	biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Binding affinity to human cloned dopamine D3 receptor	biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2337	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P04156	RO:0002436	drug_central	Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cells	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2338	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2340	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Compound was tested for its inhibitory potency against angiotensin I converting enzyme.	biolink:Association
DrugCentral:2342	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:2343	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central	Mechanism of Action; CHEMBL1876; SINGLE PROTEIN	biolink:Association
DrugCentral:2345	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:O95259	RO:0002436	drug_central		biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q96RP8	RO:0002436	drug_central		biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q8IWT1	RO:0002436	drug_central		biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q9NY72	RO:0002436	drug_central		biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:O60939	RO:0002436	drug_central		biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q07699	RO:0002436	drug_central		biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity model	biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Inhibition of human heart sodium channel Nav1.5 by patch-clamp method	biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human Potassium channel HERG expressed in mammalian cells	biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central	Inhibition of human BChE by Ellman's method	biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	CYP2D6 catalyzed AMMC-O-demethylation in HepG2 transfected cells	biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:Q7RTT9	RO:0002436	drug_central		biolink:Association
DrugCentral:2346	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central		biolink:Association
DrugCentral:2350	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2350	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2350	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2350	biolink:molecularly_interacts_with	UniProtKB:P05023	RO:0002436	drug_central		biolink:Association
DrugCentral:2350	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2350	biolink:molecularly_interacts_with	UniProtKB:P20648	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095173; PROTEIN COMPLEX	biolink:Association
DrugCentral:2350	biolink:molecularly_interacts_with	UniProtKB:P51164	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095173; PROTEIN COMPLEX	biolink:Association
DrugCentral:2350	biolink:molecularly_interacts_with	UniProtKB:P49327	RO:0002436	drug_central		biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central		biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P05231	RO:0002436	drug_central		biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:Q99527	RO:0002436	drug_central		biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central		biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:O14939	RO:0002436	drug_central	Inhibition of human PLD2 assessed as release of methyl-[3H]choline from choline-methyl-[3H]dipalmitoylphosphatidylcholine after 30 mins by exogenous substrate assay	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central	Agonist activity at PXR (unknown origin) expressed in human HepG2 cells assessed as induction of CYP3A4 transactivation after 16 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:Q13393	RO:0002436	drug_central	Inhibition of human PLD1b	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in CHO cells by liquid scintillation counting	biolink:Association
DrugCentral:2351	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assay	biolink:Association
DrugCentral:2352	biolink:molecularly_interacts_with	UniProtKB:P32246	RO:0002436	drug_central	Binding affinity to CCR1	biolink:Association
DrugCentral:2353	biolink:molecularly_interacts_with	UniProtKB:P15328	RO:0002436	drug_central		biolink:Association
DrugCentral:2353	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central		biolink:Association
DrugCentral:2353	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central	Inhibition of human recombinant His-tagged thymidylate synthase assessed as N5,N10-methylenetetrahydrofolate oxidation to dihydrofolate after 20 mins by UV spectrophotometric analysis	biolink:Association
DrugCentral:2353	biolink:molecularly_interacts_with	UniProtKB:P41440	RO:0002436	drug_central		biolink:Association
DrugCentral:2353	biolink:molecularly_interacts_with	UniProtKB:Q96NT5	RO:0002436	drug_central		biolink:Association
DrugCentral:2353	biolink:molecularly_interacts_with	UniProtKB:P14207	RO:0002436	drug_central		biolink:Association
DrugCentral:2354	biolink:molecularly_interacts_with	UniProtKB:Q13258	RO:0002436	drug_central	Binding affinity to prostanoid DP1 receptor	biolink:Association
DrugCentral:2354	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y4	RO:0002436	drug_central	Inhibition of [3H]PGD-2 binding to human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)	biolink:Association
DrugCentral:2354	biolink:molecularly_interacts_with	UniProtKB:P21731	RO:0002436	drug_central	Binding affinity to thromboxane receptor	biolink:Association
DrugCentral:2355	biolink:molecularly_interacts_with	UniProtKB:P49286	RO:0002436	drug_central		biolink:Association
DrugCentral:2355	biolink:molecularly_interacts_with	UniProtKB:P48039	RO:0002436	drug_central		biolink:Association
DrugCentral:2356	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central		biolink:Association
DrugCentral:2357	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Binding affinity to human 5HT3A receptor	biolink:Association
DrugCentral:2358	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:2358	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of guinea pig acetylcholinesterase	biolink:Association
DrugCentral:2358	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2359	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2359	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2359	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Mechanism of Action; CHEMBL1980; SINGLE PROTEIN	biolink:Association
DrugCentral:2361	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	In vitro binding affinity against human norepinephrine transporter in human embryonic kidney cell line by using [3H]-nisoxatine radioligand	biolink:Association
DrugCentral:2361	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	In vitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)	biolink:Association
DrugCentral:2361	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	In vitro competitive binding versus [N-methyl-3H]WIN-35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)	biolink:Association
DrugCentral:2361	biolink:molecularly_interacts_with	UniProtKB:P48051	RO:0002436	drug_central		biolink:Association
DrugCentral:2361	biolink:molecularly_interacts_with	UniProtKB:P48549	RO:0002436	drug_central		biolink:Association
DrugCentral:2361	biolink:molecularly_interacts_with	UniProtKB:P48544	RO:0002436	drug_central		biolink:Association
DrugCentral:2361	biolink:molecularly_interacts_with	UniProtKB:P48549	RO:0002436	drug_central		biolink:Association
DrugCentral:2361	biolink:molecularly_interacts_with	UniProtKB:P48051	RO:0002436	drug_central		biolink:Association
DrugCentral:2361	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2361	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2362	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central		biolink:Association
DrugCentral:2362	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central		biolink:Association
DrugCentral:2363	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:2365	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity to 5HT1A receptor	biolink:Association
DrugCentral:2365	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity to dopamine receptor D2 cloned from human, using [3H]- YM09151 as competitive ligand	biolink:Association
DrugCentral:2365	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Displacement of [3H]-YM 09151 from human Dopamine receptor D4	biolink:Association
DrugCentral:2365	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047	biolink:Association
DrugCentral:2365	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2365	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2366	biolink:molecularly_interacts_with	UniProtKB:Q9Y6L6	RO:0002436	drug_central		biolink:Association
DrugCentral:2366	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central		biolink:Association
DrugCentral:2366	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:2366	biolink:molecularly_interacts_with	UniProtKB:O60706	RO:0002436	drug_central		biolink:Association
DrugCentral:2366	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central		biolink:Association
DrugCentral:2366	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2366	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	Displacement of [3H]glibenclamide from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)	biolink:Association
DrugCentral:2368	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2369	biolink:molecularly_interacts_with	UniProtKB:Q05940	RO:0002436	drug_central	Mechanism of Action; CHEMBL1893; SINGLE PROTEIN	biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:Q05940	RO:0002436	drug_central		biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:P54219	RO:0002436	drug_central		biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affinity model	biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2370	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central	Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells by Hoechst 33342 assay	biolink:Association
DrugCentral:2372	biolink:molecularly_interacts_with	UniProtKB:P02753	RO:0002436	drug_central	Binding affinity to His-tagged recombinant human sRBP expressed in Escherichia coli BL21(DE3) assessed as apparent dissociation constant after 5 mins by fluorescence spectrophotometric analysis	biolink:Association
DrugCentral:2373	biolink:molecularly_interacts_with	UniProtKB:P20839	RO:0002436	drug_central	<i>In vitro</i> inhibition of IMPDH (isoform not specified, human and mouse assayed)	biolink:Association
DrugCentral:2373	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central	Inhibition of human topoisomerase 1 activity assessed as DNA triplex formation and presence of supercoiled DNA by microplate assay	biolink:Association
DrugCentral:2373	biolink:molecularly_interacts_with	UniProtKB:P49902	RO:0002436	drug_central		biolink:Association
DrugCentral:2373	biolink:molecularly_interacts_with	UniProtKB:P22413	RO:0002436	drug_central		biolink:Association
DrugCentral:2373	biolink:molecularly_interacts_with	UniProtKB:P55263	RO:0002436	drug_central		biolink:Association
DrugCentral:2373	biolink:molecularly_interacts_with	UniProtKB:P12268	RO:0002436	drug_central	<i>In vitro</i> inhibition of IMPDH (isoform not specified, human and mouse assayed)	biolink:Association
DrugCentral:2377	biolink:molecularly_interacts_with	UniProtKB:P29466	RO:0002436	drug_central	DRUGMATRIX: Protease, Caspase 1 enzyme inhibition (substrate: Ac-YVAD-AMC)	biolink:Association
DrugCentral:2377	biolink:molecularly_interacts_with	UniProtKB:Q9NPD5	RO:0002436	drug_central		biolink:Association
DrugCentral:2377	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central	Activation of PXR in human DPX2 cells after 24 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:2377	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay	biolink:Association
DrugCentral:2377	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:2377	biolink:molecularly_interacts_with	UniProtKB:P46721	RO:0002436	drug_central		biolink:Association
DrugCentral:2377	biolink:molecularly_interacts_with	UniProtKB:Q9Y6L6	RO:0002436	drug_central	Inhibition of atorvastatin transport by OATP1B1.	biolink:Association
DrugCentral:2379	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central	Transactivation of human PXR expressed in HepG2 cells after 18 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:2381	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Displacement of [3H]RX821001 from human alpha2B adrenoceptor expressed in CHO cells after 60 mins by gamma counter	biolink:Association
DrugCentral:2381	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Displacement of [3H]RX821001 from human alpha2C adrenoceptor expressed in CHO cells after 60 mins by gamma counter	biolink:Association
DrugCentral:2381	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central	Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2AR	biolink:Association
DrugCentral:2381	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Displacement of [3H]RX821001 from human alpha2A adrenoceptor expressed in CHO cells after 60 mins by gamma counter	biolink:Association
DrugCentral:2381	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2382	biolink:molecularly_interacts_with	UniProtKB:O15554	RO:0002436	drug_central		biolink:Association
DrugCentral:2382	biolink:molecularly_interacts_with	UniProtKB:Q9UGI6	RO:0002436	drug_central		biolink:Association
DrugCentral:2382	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2382	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:2382	biolink:molecularly_interacts_with	UniProtKB:Q8TCU5	RO:0002436	drug_central		biolink:Association
DrugCentral:2382	biolink:molecularly_interacts_with	UniProtKB:Q92952	RO:0002436	drug_central		biolink:Association
DrugCentral:2383	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2383	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2384	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:2387	biolink:molecularly_interacts_with	UniProtKB:P14324	RO:0002436	drug_central	Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 mins	biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Binding affinity to human cloned muscarinic M1 receptor	biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Binding affinity against dopamine receptor D1	biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Binding affinity to human SERT	biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity measured at the sigma receptor by the inhibition of [3H]-3-PPP binding to guinea pig cerebellum using unlabeled 3-PPP for nonspecific binding.	biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]5-LSD from human 5HT6 receptor expressed in human HeLa cells	biolink:Association
DrugCentral:2389	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:2390	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2390	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central	DRUGMATRIX: Vasopressin V1A radioligand binding (ligand: [125I] PhenylacetylTyr(Me)PheGlnAsnArgProArgTyr)	biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of human OCT1-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells up to 500 uM after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2391	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated [14]-metformin uptake expressed in HEK293 cells after 1.5 mins by scintillation counting analysis	biolink:Association
DrugCentral:2392	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human erythrocytes BChE	biolink:Association
DrugCentral:2392	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central	Inhibition of human recombinant butyrylcholinesterase	biolink:Association
DrugCentral:2393	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2393	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2393	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:2393	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2393	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Binding activity against 5-hydroxytryptamine 2C receptor from pig cortex membrane using [3H]mesulergine as radioligand.	biolink:Association
DrugCentral:2393	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Binding activity against 5-hydroxytryptamine 2C receptor from human brain cortex using [3H]mesulergine as radioligand.	biolink:Association
DrugCentral:2393	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptor	biolink:Association
DrugCentral:2393	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:2396	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:2396	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:2396	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:2396	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2396	biolink:molecularly_interacts_with	UniProtKB:P07510	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2396	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2396	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2397	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central		biolink:Association
DrugCentral:2397	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes. 	biolink:Association
DrugCentral:2397	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2402	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2403	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central		biolink:Association
DrugCentral:2403	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central		biolink:Association
DrugCentral:2403	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central		biolink:Association
DrugCentral:2403	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central		biolink:Association
DrugCentral:2403	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central		biolink:Association
DrugCentral:2403	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central		biolink:Association
DrugCentral:2403	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:2403	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central		biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:O14842	RO:0002436	drug_central		biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA))	biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Competitive inhibition of human MAOA expressed in Pichia pastoris	biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central	In vitro transcription activation on human peroxisome proliferator activated receptor-delta (PPAR delta)	biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Competitive inhibition of human MAOB expressed in Pichia pastoris	biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Agonist activity at human PPARalpha ligand binding domain expressed in human HepG2 cells co-transfected with Gal4 by luciferase reporter gene assay	biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:P13631	RO:0002436	drug_central	Binding affinity against Retinoic acid receptor gamma was determined in vitro by using [3H]ATRA as radioligand	biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:Q9UL62	RO:0002436	drug_central		biolink:Association
DrugCentral:2405	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:2406	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central	Inhibitory constant against HMG-CoA reductase	biolink:Association
DrugCentral:2406	biolink:molecularly_interacts_with	UniProtKB:O43924	RO:0002436	drug_central	Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay	biolink:Association
DrugCentral:2407	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2407	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2407	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2407	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2407	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D4.2 of CHO K-1 cells.	biolink:Association
DrugCentral:2408	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:2410	biolink:molecularly_interacts_with	UniProtKB:O43193	RO:0002436	drug_central		biolink:Association
DrugCentral:2413	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Inhibitory concentration against histamine H1 receptor	biolink:Association
DrugCentral:2413	biolink:molecularly_interacts_with	UniProtKB:P25105	RO:0002436	drug_central	Inhibitory concentration against platelet activating factor receptor	biolink:Association
DrugCentral:2414	biolink:molecularly_interacts_with	UniProtKB:P11086	RO:0002436	drug_central	Activity of human wild type PNMT assessed as phenylethanolamine methylation	biolink:Association
DrugCentral:2414	biolink:molecularly_interacts_with	UniProtKB:P22061	RO:0002436	drug_central	Kinetic constant was measured for PMII of Leishmania donovani promastigotes using supernatant (S12) fraction	biolink:Association
DrugCentral:2414	biolink:molecularly_interacts_with	UniProtKB:Q99873	RO:0002436	drug_central	Inhibition of GST-fused human recombinant PRMT1 after 90 mins by SDS-PAGE based scintillation counting	biolink:Association
DrugCentral:2416	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:2416	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:2416	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assay	biolink:Association
DrugCentral:2416	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:2416	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 catalytic domain by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:2416	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 catalytic domain by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:2416	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 6 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:2416	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay	biolink:Association
DrugCentral:2419	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2419	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assay	biolink:Association
DrugCentral:2419	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Displacement of [3H]CGP12177 from human beta-1 adrenoceptor	biolink:Association
DrugCentral:2419	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	Agonist activity at human recombinant beta3 receptor assessed as cAMP accumulation by radioimmunoassay and cell based assay	biolink:Association
DrugCentral:2419	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central	DRUGMATRIX: Vasopressin V1A radioligand binding (ligand: [125I] PhenylacetylTyr(Me)PheGlnAsnArgProArgTyr)	biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2422	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:2423	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2423	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2423	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2424	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2424	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	Displacement of [3H]NMS from human M5 muscarinic receptor expressed in CHO-K1 cells	biolink:Association
DrugCentral:2424	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2424	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2424	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2428	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:2428	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2428	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2428	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2429	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2429	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2429	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of human MAO-A expressed in BTI insect cells using p-tyramine as substrate after 60 mins	biolink:Association
DrugCentral:2429	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Irreversible inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated for 30 mins by Lineweaver-Burk plot analysis	biolink:Association
DrugCentral:2432	biolink:molecularly_interacts_with	UniProtKB:P21731	RO:0002436	drug_central	In vitro concentration that reduced specific binding of [3H]U-440619 to guinea pig platelet receptor, TXA2 by 50%	biolink:Association
DrugCentral:2433	biolink:molecularly_interacts_with	UniProtKB:Q02643	RO:0002436	drug_central		biolink:Association
DrugCentral:2434	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Inhibition of human ABCB1-mediated rhodamine 123 efflux in mouse L5178 cells expressing human MDR1 after 20 mins by FACS analysis	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Ability to displace [3H]5-CT (2.0 nM) from HeLa cells of human 5-hydroxytryptamine 1A receptor	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Displacement of [3H]prozosin from human cloned dopamine D2 receptor expressed in CHO cells	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Binding affinity towards human Dopamine receptor D1	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Displacement of [3H]-YM-09151-2 (0.06 nM) from human Dopamine receptor D4 expressed in CHO cells	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Displacement of [3H]prozosin from human cloned 5HT2C receptor expressed in CHO cells	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central	Ability to displace [3H]5-CT (1.5 nM) from HeLa cells of human 5-hydroxytryptamine 1B receptor	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Binding affinity towards Serotonin 5-hydroxytryptamine 2A receptor	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Displacement of [3H]prozosin from human cloned histamine H1 receptor expressed in CHO cells	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Ability to displace [3H]spiperone (0.3 nM) from CHO cells of human Dopamine receptor D3	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human cloned ERG expressed in CHO cells assessed as inhibition of potassium channel current by automated patch clamp assay	biolink:Association
DrugCentral:2435	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]5-LSD from human 5HT6 receptor expressed in human HeLa cells	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Equilibrium dissociation constant (KD) for Competitive binding between [3H]- imipramine and the compound at human transporter-hSERT	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity to sigma 1 receptor	biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2436	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2437	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:P57789	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331041; SINGLE PROTEIN	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:Q7Z418	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331042; SINGLE PROTEIN	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:O14649	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321613; SINGLE PROTEIN	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:Q9NPC2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321614; SINGLE PROTEIN	biolink:Association
DrugCentral:2439	biolink:molecularly_interacts_with	UniProtKB:O95069	RO:0002436	drug_central	Mechanism of Action; CHEMBL2321615; SINGLE PROTEIN	biolink:Association
DrugCentral:2440	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2440	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2440	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2440	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2440	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:2440	biolink:molecularly_interacts_with	UniProtKB:Q9UK17	RO:0002436	drug_central		biolink:Association
DrugCentral:2440	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central		biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX)	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:P16499	RO:0002436	drug_central		biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q9NPD5	RO:0002436	drug_central		biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q13946	RO:0002436	drug_central	Inhibition of human recombinant PDE7A1 at 1 uM by [3H]cGMP based tritium scintillation proximity assay	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:O76083	RO:0002436	drug_central	Inhibition of Phosphodiesterase 9	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of human recombinant PDE4 (Phosphodiesterase 4)	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibition of human recombinant PDE4 (Phosphodiesterase 4)	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Inhibition of human recombinant PDE4 (Phosphodiesterase 4)	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of human recombinant PDE4 (Phosphodiesterase 4)	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human Potassium channel HERG expressed in mammalian cells	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of human PDE4D	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:O15440	RO:0002436	drug_central	Inhibition of ABCC5 in human erythrocytes assessed as inhibition of ATP-mediated [3H]cGMP uptake in inside-out vesicles after 60 mins by liquid scintillation counting	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counter	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:P51160	RO:0002436	drug_central	Inhibition of human recombinant PDE6C at 1 uM by [3H]cGMP based tritium scintillation proximity assay	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:P54750	RO:0002436	drug_central	Inhibitory activity against phosphodiesterase-1 (PDE1) isolated from canine lung	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q01064	RO:0002436	drug_central	Inhibitory activity against phosphodiesterase-1 (PDE1) isolated from canine lung	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q14123	RO:0002436	drug_central	Inhibitory activity against phosphodiesterase-1 (PDE1) isolated from canine lung	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Inhibitory concentration against phosphodiesterase 3 from human platelet	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Inhibitory concentration against phosphodiesterase 3 from human platelet	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q9HCR9	RO:0002436	drug_central	Inhibition of human phosphodiesterase 11	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:Q9Y233	RO:0002436	drug_central	Inhibitory concentration against human phosphodiesterase 10	biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:O60658	RO:0002436	drug_central		biolink:Association
DrugCentral:2441	biolink:molecularly_interacts_with	UniProtKB:O00408	RO:0002436	drug_central		biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5a after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5b after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 6 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 13 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:P00749	RO:0002436	drug_central	Inhibition of urokinase amidolytic activity (unknown origin)	biolink:Association
DrugCentral:2443	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysis	biolink:Association
DrugCentral:2445	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central		biolink:Association
DrugCentral:2445	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:P62942	RO:0002436	drug_central		biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:Q00688	RO:0002436	drug_central		biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:P42345	RO:0002436	drug_central	Inhibition of mTOR kinase expressed in human HEK293 cells by Western blot analysis	biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:P06730	RO:0002436	drug_central	Binding affinity to purified elF4E	biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:Q53EL6	RO:0002436	drug_central	Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required for 50% recovery of Pdcd4-luciferase signal incubated for 8 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:Q13451	RO:0002436	drug_central	Binding affinity to human FKBP51 by competitive fluorescence polarization assay	biolink:Association
DrugCentral:2446	biolink:molecularly_interacts_with	UniProtKB:P68106	RO:0002436	drug_central		biolink:Association
DrugCentral:2448	biolink:molecularly_interacts_with	UniProtKB:Q9UHL4	RO:0002436	drug_central		biolink:Association
DrugCentral:2448	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central		biolink:Association
DrugCentral:2448	biolink:molecularly_interacts_with	UniProtKB:Q6V1X1	RO:0002436	drug_central	Inhibition of human DPP8 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to addition of substrate measured after 30 mins	biolink:Association
DrugCentral:2448	biolink:molecularly_interacts_with	UniProtKB:Q86TI2	RO:0002436	drug_central	Inhibition of human DPP9 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to addition of substrate measured after 30 mins	biolink:Association
DrugCentral:2448	biolink:molecularly_interacts_with	UniProtKB:Q12884	RO:0002436	drug_central		biolink:Association
DrugCentral:2451	biolink:molecularly_interacts_with	UniProtKB:P19838	RO:0002436	drug_central	Inhibition of NF-KB p50 subunit/DNA interaction after 20 mins by EMSA	biolink:Association
DrugCentral:2451	biolink:molecularly_interacts_with	UniProtKB:P06746	RO:0002436	drug_central	Inhibition of DNA polymerase beta lyase activity by deoxyribose phosphate excision assay	biolink:Association
DrugCentral:2451	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central	Inhibition of human DPP4 using H-Gly-Pro-AMC peptide substrate assessed as increase in fluorescence for 20 mins by fluorimetric assay	biolink:Association
DrugCentral:2452	biolink:molecularly_interacts_with	UniProtKB:P24158	RO:0002436	drug_central		biolink:Association
DrugCentral:2452	biolink:molecularly_interacts_with	UniProtKB:P08246	RO:0002436	drug_central	Binding affinity against Elastase.	biolink:Association
DrugCentral:2457	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 1 hr by scintillation counting	biolink:Association
DrugCentral:2457	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation counting	biolink:Association
DrugCentral:2457	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation counting	biolink:Association
DrugCentral:2457	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2457	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P49336	RO:0002436	drug_central	Binding constant for CDK8 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q92772	RO:0002436	drug_central	Binding affinity to CDKL2	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Average Binding Constant for ABL1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(K663Q) kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O15146	RO:0002436	drug_central	Binding constant for MUSK kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central	Binding constant for FLT1 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P45984	RO:0002436	drug_central	Average Binding Constant for JNK2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Inhibition of recombinant c-Src by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 60 mins by activity based 100 fold dilution assay	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Binding constant for FGFR3 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Inhibition of recombinant INSR by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Binding constant for PDGFRA kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q8WXR4	RO:0002436	drug_central	Binding constant for MYO3B kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Displacement of [3H]8-OH-DPAT from 5HT1A receptor after 1.5 hrs by scintillation counter	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q96Q40	RO:0002436	drug_central	Binding affinity to PFTAIRE2	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Binding constant for RIPK2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central	Binding constant for EPHB4 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9UK32	RO:0002436	drug_central	Binding constant for RPS6KA6(Kin.Dom.2 - N-terminal) kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Inhibition of recombinant GST-tagged Aurora A expressed in Sf9 insect cells after 90 mins by Kinase-Glo assay	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9NYL2	RO:0002436	drug_central	Binding constant for ZAK kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9H422	RO:0002436	drug_central	Binding affinity to HIPK3	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9H2X6	RO:0002436	drug_central	Binding affinity to HIPK2	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P04049	RO:0002436	drug_central	Inhibition of C-RAF	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q8IVW4	RO:0002436	drug_central	Binding affinity to CDKL3	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Displacement of [3H]LSD from 5HT2C receptor after 1.5 hrs by scintillation counter	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Displacement of [3H]Ketanserin from 5HT2A receptor after 1.5 hrs by scintillation counter	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P21709	RO:0002436	drug_central	Binding constant for EPHA1 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for HPK1 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q8TD08	RO:0002436	drug_central	Binding constant for ERK8 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9BUB5	RO:0002436	drug_central	Binding constant for full-length MKNK1	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P15056	RO:0002436	drug_central	Inhibition of B-Raf	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O43318	RO:0002436	drug_central	Binding affinity to TAK1	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Average Binding Constant for FRK; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P49759	RO:0002436	drug_central	Binding constant for CLK1 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q86Z02	RO:0002436	drug_central	Binding affinity to HIPK1	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P29322	RO:0002436	drug_central	Average Binding Constant for EPHA8; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P33981	RO:0002436	drug_central	Binding constant for TTK kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P29317	RO:0002436	drug_central	Binding constant for EPHA2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Binding constant for EPHA3 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Average Binding Constant for STK10; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Average Binding Constant for STK18; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central	Binding affinity to CSK	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q7L7X3	RO:0002436	drug_central	Binding affinity to TAO1	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q59H18	RO:0002436	drug_central	Binding constant for full-length TNNI3K	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Binding constant for full-length AURKC	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central	Average Binding Constant for NTRK1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	Average Binding Constant for FGFR1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Binding constant for FGFR2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O14578	RO:0002436	drug_central	Binding constant for CIT kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding affinity to HIPK4	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9NRP7	RO:0002436	drug_central	Binding constant for STK36 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(V559D) kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Average Binding Constant for EPHA6; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q96GD4	RO:0002436	drug_central	Binding constant for AURKB kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Displacement of [3H]LSD from 5HT2B receptor after 1.5 hrs by scintillation counter	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9HBH9	RO:0002436	drug_central	Binding constant for MKNK2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q15375	RO:0002436	drug_central	Average Binding Constant for EPHA7; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9UL54	RO:0002436	drug_central	Binding constant for TAOK2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P54756	RO:0002436	drug_central	Average Binding Constant for EPHA5; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P53667	RO:0002436	drug_central	Binding constant for full-length LIMK1	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P54764	RO:0002436	drug_central	Average Binding Constant for EPHA4; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central	Average Binding Constant for EPHB1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central	Binding constant for TRKC kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P24941	RO:0002436	drug_central	Binding constant for CDK2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Average Binding Constant for ABL2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding constant for TIE2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding affinity to EPHB6	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central	Displacement of [3H]LSD from 5HT5A receptor after 1.5 hrs by scintillation counter	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P34913	RO:0002436	drug_central	Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carbonate conversion to 6-methoxy-2-naphthaldehyde preincubated for 5 mins prior to substrate addition by fluorescence assay	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]LSD from 5HT6 receptor after 1.5 hrs by scintillation counter	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9H2K8	RO:0002436	drug_central	Binding affinity to TAOK3	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9H3Y6	RO:0002436	drug_central	Binding constant for SRMS kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P48729	RO:0002436	drug_central	Inhibition of recombinant CK1 by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q00526	RO:0002436	drug_central	Binding constant for CDK3 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P50613	RO:0002436	drug_central	Binding constant for full-length CDK7	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P35916	RO:0002436	drug_central	Average Binding Constant for FLT4; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central	Binding constant for DDR2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q00537	RO:0002436	drug_central	Binding constant for full-length PCTK2	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O94921	RO:0002436	drug_central	Binding constant for full-length PFTK1	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P37173	RO:0002436	drug_central	Binding constant for TGFBR2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(M918T) kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O95819	RO:0002436	drug_central	Binding constant for MAP4K4 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:O15264	RO:0002436	drug_central	Binding affinity to p38-delta	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9H1R3	RO:0002436	drug_central	Average Binding Constant for MYLK2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding affinity to YSK4	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central	Binding constant for TRKB kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P29323	RO:0002436	drug_central	Binding constant for EPHB2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q15759	RO:0002436	drug_central	Average Binding Constant for p38-beta; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P53671	RO:0002436	drug_central	Binding constant for LIMK2 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q32MK0	RO:0002436	drug_central	Binding constant for MLCK kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	Displacement of [3H]LSD from 5HT7 receptor after 1.5 hrs by scintillation counter	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q00535	RO:0002436	drug_central	Average Binding Constant for CDK5; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9BWU1	RO:0002436	drug_central	Binding constant for CDK11 kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9BYT3	RO:0002436	drug_central	Binding constant for full-length STK33	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q9UBE8	RO:0002436	drug_central	Binding constant for full-length NLK	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P53778	RO:0002436	drug_central	Binding constant for full-length p38-gamma	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	Average Binding Constant for p38-alpha; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:Q13470	RO:0002436	drug_central	Binding constant for full-length TNK1	biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central		biolink:Association
DrugCentral:2459	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central		biolink:Association
DrugCentral:2463	biolink:molecularly_interacts_with	UniProtKB:O00142	RO:0002436	drug_central	Inhibition of thymidine kinase 2	biolink:Association
DrugCentral:2464	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2464	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2464	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2466	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity to 5HT1A receptor	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 5A receptor was evaluated using [3H]-5-CT as radioligand	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 6 receptor	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity against dopamine receptor D2 by using [3H]spiperone as radioligand in caudate-putamen of monkey	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Binding affinity against dopamine receptor D1 by using [3H]-SCH- 23390 as radioligand in caudate-putamen of monkey	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Displacement of [3H]Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cells after 2 hrs	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Evaluated for the binding affinity to porcine choroid plexus at 5-hydroxytryptamine 2C receptor binding site by using [3H]-MES as a radioligand.	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Displacement of [3H]Ketanserin from human 5HT2A receptor expressed in HEK293 cells	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding constant measured against Alpha-1A adrenergic receptor in human prostate; ++:moderately active	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Displacement of [3H]Spiperone from human recombinant dopamine D3 receptor expressed in CHO cells after 2 hrs	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	The compound was tested for affinity towards sigma-3 receptor	biolink:Association
DrugCentral:2470	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 7 receptor	biolink:Association
DrugCentral:2474	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Compound tested in vitro for inhibition of Angiotensin I converting enzyme	biolink:Association
DrugCentral:2475	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central		biolink:Association
DrugCentral:2475	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2475	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:2475	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:2475	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:2475	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Binding affinity to human androgen receptor	biolink:Association
DrugCentral:2475	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Agonist activity at estrogen receptor beta (unknown origin) by NH Pro assay	biolink:Association
DrugCentral:2475	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2477	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2477	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2477	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	biolink:Association
DrugCentral:2477	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2477	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2477	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Mechanism of Action; CHEMBL1871; SINGLE PROTEIN	biolink:Association
DrugCentral:2480	biolink:molecularly_interacts_with	UniProtKB:P30531	RO:0002436	drug_central		biolink:Association
DrugCentral:2480	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central		biolink:Association
DrugCentral:2480	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central		biolink:Association
DrugCentral:2480	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:2484	biolink:molecularly_interacts_with	UniProtKB:P59540	RO:0002436	drug_central	calcium imaging in ransfected human embryonic kidney (HEK)-293T	biolink:Association
DrugCentral:2484	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2484	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2484	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2484	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2484	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central	GRAC: human Glycine receptor subunit alpha-1 selective antagonist	biolink:Association
DrugCentral:2484	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2484	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2484	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2487	biolink:molecularly_interacts_with	UniProtKB:Q9GZT9	RO:0002436	drug_central	Inhibition of 2-oxoglutarate-dependent human recombinant HIF PHD2 preincubated for 1 hr	biolink:Association
DrugCentral:2489	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2489	biolink:molecularly_interacts_with	UniProtKB:P07510	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2489	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2489	biolink:molecularly_interacts_with	UniProtKB:Q04844	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2489	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2491	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:2491	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:2491	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:2492	biolink:molecularly_interacts_with	UniProtKB:P83111	RO:0002436	drug_central		biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assay	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P40925	RO:0002436	drug_central	Inhibition of malate dehydrogenase (MDH)	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P05186	RO:0002436	drug_central	PUBCHEM_BIOASSAY: uHTS identification of compounds activating TNAP in the absence of phosphate acceptor performed in luminescent assay. (Class of assay: confirmatory) [Related pubchem assays: 813, 518, 1548, 1450 ]	biolink:Association
DrugCentral:2495	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central		biolink:Association
DrugCentral:2497	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central	Inhibition of human DHFR after 2 mins	biolink:Association
DrugCentral:2500	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Inhibition of aurora kinase A	biolink:Association
DrugCentral:2500	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2500	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2500	biolink:molecularly_interacts_with	UniProtKB:Q9GZV3	RO:0002436	drug_central		biolink:Association
DrugCentral:2501	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2502	biolink:molecularly_interacts_with	UniProtKB:Q04760	RO:0002436	drug_central		biolink:Association
DrugCentral:2505	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	Inhibitory activity against human thrombin (using Chromozym TH as the substrate)	biolink:Association
DrugCentral:2505	biolink:molecularly_interacts_with	UniProtKB:P07477	RO:0002436	drug_central	Inhibitory activity against human trypsin (using Chromozym TH as the substrate)	biolink:Association
DrugCentral:2505	biolink:molecularly_interacts_with	UniProtKB:P07478	RO:0002436	drug_central	Inhibitory activity against human trypsin (using Chromozym TH as the substrate)	biolink:Association
DrugCentral:2505	biolink:molecularly_interacts_with	UniProtKB:P35030	RO:0002436	drug_central	Inhibitory activity against human trypsin (using Chromozym TH as the substrate)	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VA	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Ki value against human carbonic anhydrase II	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Ki value against human carbonic anhydrase VII	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibitory constant against catalytic domain of human carbonic anhydrase XII	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of catalytic domain of human recombinant CA IX	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of cloned isozyme, human carbonic anhydrase IV	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assay	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VB	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human recombinant CA3 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant CA13 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:2521	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of full length human recombinant CA VI	biolink:Association
DrugCentral:2523	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central		biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:P29466	RO:0002436	drug_central	DRUGMATRIX: Protease, Caspase 1 enzyme inhibition (substrate: Ac-YVAD-AMC)	biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:P03956	RO:0002436	drug_central	DRUGMATRIX: Peptidase, Matrix Metalloproteinase-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:P24752	RO:0002436	drug_central		biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 esterase activity by non-competitive Lineweaver-Burke plot	biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:Q9UPY5	RO:0002436	drug_central	Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid scintillation counting	biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 esterase activity by noncompetitive Lineweaver-Burke plot	biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094253; PROTEIN FAMILY	biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094253; PROTEIN FAMILY	biolink:Association
DrugCentral:2525	biolink:molecularly_interacts_with	UniProtKB:Q96NT5	RO:0002436	drug_central		biolink:Association
DrugCentral:2527	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central		biolink:Association
DrugCentral:2528	biolink:molecularly_interacts_with	UniProtKB:P21462	RO:0002436	drug_central		biolink:Association
DrugCentral:2528	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:2528	biolink:molecularly_interacts_with	UniProtKB:Q96S37	RO:0002436	drug_central	Inhibition of human URAT1-mediated urate uptake in HEK293 cells	biolink:Association
DrugCentral:2529	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central	Inhibitory concentration against Endothelin A receptor	biolink:Association
DrugCentral:2529	biolink:molecularly_interacts_with	UniProtKB:P24530	RO:0002436	drug_central	Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparation	biolink:Association
DrugCentral:2529	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:2531	biolink:molecularly_interacts_with	UniProtKB:O60760	RO:0002436	drug_central	Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation	biolink:Association
DrugCentral:2532	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2532	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2533	biolink:molecularly_interacts_with	UniProtKB:P11413	RO:0002436	drug_central		biolink:Association
DrugCentral:2534	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2534	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central		biolink:Association
DrugCentral:2534	biolink:molecularly_interacts_with	UniProtKB:P19793	RO:0002436	drug_central	Displacement of [3H]-9-cis-RA from RXRalpha (unknown origin) by liquid scintillation counting	biolink:Association
DrugCentral:2534	biolink:molecularly_interacts_with	UniProtKB:O14684	RO:0002436	drug_central	Inhibition of microsomal PGES	biolink:Association
DrugCentral:2534	biolink:molecularly_interacts_with	UniProtKB:Q04760	RO:0002436	drug_central	Inhibition of glyoxalase 1	biolink:Association
DrugCentral:2534	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central	Inhibition of Homo sapiens (human) aldose reductase	biolink:Association
DrugCentral:2534	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2536	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Ki value against human carbonic anhydrase XII (hCA XII)	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Antagonist activity at dopamine D2 receptor (unknown origin)	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding affinity for Dopamine receptor D4	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cells	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human recombinant CA 3 assessed as CO2 hydration by stopped flow kinetic assay	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VA	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 9 by stopped-flow CO2 hydrase assay	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Ki value against human carbonic anhydrase I (hCA I)	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VB	biolink:Association
DrugCentral:2537	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of full length human recombinant CA VI	biolink:Association
DrugCentral:2538	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:2538	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:2538	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central		biolink:Association
DrugCentral:2538	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central		biolink:Association
DrugCentral:2540	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2540	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 9 catalytic domain by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:2540	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2540	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human full length recombinant carbonic anhydrase 6 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:2541	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2541	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 1F receptor was determined	biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central	Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortex	biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Compound was evaluated for the affinity at 5-hydroxytryptamine 3 receptor	biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Compound was evaluated for the affinity at 5-hydroxytryptamine 2C receptor	biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central	Binding affinity was measured on 5-hydroxytryptamine 1D receptor beta in CHO cells transfected with human 5-HT1D beta gene labeled with [3H]5-HT	biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 2A receptor from cloned Human membranes	biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central	Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1D receptor expressed in CHOK1 cells by liquid scintillation counting	biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptor	biolink:Association
DrugCentral:2543	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central	Compound was evaluated for the affinity at 5-hydroxytryptamine 1E receptor	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central		biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Binding constant for JNK3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central	Binding constant for full-length MEK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q92772	RO:0002436	drug_central	Binding affinity to CDKL2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(K663Q) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(T315I)-phosphorylated kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(L858R,T790M) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q04759	RO:0002436	drug_central	Binding constant for PRKCQ kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O15075	RO:0002436	drug_central	Binding constant for DCAMKL1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O15146	RO:0002436	drug_central	Binding constant for MUSK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P48736	RO:0002436	drug_central	Inhibition of recombinant PI3Kgamma by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P45984	RO:0002436	drug_central	Binding constant for JNK2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of KDR by cellular assay	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Binding constant for FGFR3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q14012	RO:0002436	drug_central	Binding constant for full-length CAMK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8TDR2	RO:0002436	drug_central	Binding affinity to STK35	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Average Binding Constant for INSR; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q16566	RO:0002436	drug_central	Binding constant for CAMK4 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8TDC3	RO:0002436	drug_central	Binding constant for BRSK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P22455	RO:0002436	drug_central	Binding constant for FGFR4 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q96SB4	RO:0002436	drug_central	Binding constant for full-length SRPK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q92630	RO:0002436	drug_central	Binding affinity to DYRK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O14730	RO:0002436	drug_central	Binding constant for full-length RIOK3	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET(M1250T) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P49674	RO:0002436	drug_central	Binding constant for full-length CSNK1E	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8WXR4	RO:0002436	drug_central	Binding constant for MYO3B kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P46734	RO:0002436	drug_central	Binding constant for MEK3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O75914	RO:0002436	drug_central	Binding constant for full-length PAK3	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13554	RO:0002436	drug_central	Binding constant for CAMK2B kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(Kin.Dom.2/JH1 - catalytic) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UK32	RO:0002436	drug_central	Binding constant for RPS6KA6(Kin.Dom.1 - C-terminal) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P27448	RO:0002436	drug_central	Binding constant for full-length MARK3	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q15418	RO:0002436	drug_central	Binding affinity to RPS6KA4(Kin.Dom.1-N-terminal)	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8IY84	RO:0002436	drug_central	Binding affinity to NIM1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q52WX2	RO:0002436	drug_central	Binding constant for SBK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q6ZN16	RO:0002436	drug_central	Binding affinity to MAP3K15	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9Y2H9	RO:0002436	drug_central	Binding affinity to MAST1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Binding constant for AURKA kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Inhibition of Jak1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P48730	RO:0002436	drug_central	Binding constant for full-length CSNK1D	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q08881	RO:0002436	drug_central	Binding constant for ITK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9H422	RO:0002436	drug_central	Binding affinity to HIPK3	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9H2X6	RO:0002436	drug_central	Binding affinity to HIPK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q86V86	RO:0002436	drug_central	Binding constant for PIM3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q14680	RO:0002436	drug_central	Binding constant for full-length MELK	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P30291	RO:0002436	drug_central	Binding constant for WEE1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central	Binding constant for BTK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P19525	RO:0002436	drug_central	Binding constant for PRKR kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O60285	RO:0002436	drug_central	Binding constant for ARK5 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8IWQ3	RO:0002436	drug_central	Binding constant for full-length BRSK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O43172	RO:0002436	drug_central	Binding affinity to PRP4	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q15139	RO:0002436	drug_central	Binding constant for PRKD1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O43283	RO:0002436	drug_central	Binding affinity to LZK	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UHD2	RO:0002436	drug_central	Binding affinity to TBK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UPZ9	RO:0002436	drug_central	Binding affinity to ICK	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8TDX7	RO:0002436	drug_central	Binding constant for full-length NEK7	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for MAP4K1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O75460	RO:0002436	drug_central	Binding affinity to ERN1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9BUB5	RO:0002436	drug_central	Binding constant for MKNK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q96L34	RO:0002436	drug_central	Binding constant for MARK4 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O95747	RO:0002436	drug_central	Binding affinity to OSR1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O94806	RO:0002436	drug_central	Binding constant for PRKD3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q96BR1	RO:0002436	drug_central	Binding constant for SGK3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UEW8	RO:0002436	drug_central	Binding affinity to STK39	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O43318	RO:0002436	drug_central	Binding affinity to TAK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P49760	RO:0002436	drug_central	Binding constant for CLK2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8WTQ7	RO:0002436	drug_central	Binding affinity to GRK7	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q86YV6	RO:0002436	drug_central	Binding constant for SgK085 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q86Z02	RO:0002436	drug_central	Binding constant for HIPK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P49759	RO:0002436	drug_central	Binding constant for full-length CLK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P33981	RO:0002436	drug_central	Binding constant for TTK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q86UE8	RO:0002436	drug_central	Binding constant for TLK2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Binding constant for EPHA3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P16591	RO:0002436	drug_central	Binding constant for FER kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O75716	RO:0002436	drug_central	Binding constant for STK16 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O94768	RO:0002436	drug_central	Binding constant for full-length DRAK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13555	RO:0002436	drug_central	Binding affinity to CAMK1G	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Binding constant for PLK4 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q2M2I8	RO:0002436	drug_central	Binding constant for AAK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q7KZI7	RO:0002436	drug_central	Binding constant for MARK2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O75582	RO:0002436	drug_central	Binding affinity to RPS6KA2(Kin.Dom.1-N-terminal)	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P19784	RO:0002436	drug_central	Binding constant for CSNK2A2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q15208	RO:0002436	drug_central	Binding affinity to NDR1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q16513	RO:0002436	drug_central	Binding constant for PKN2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q7L7X3	RO:0002436	drug_central	Binding affinity to TAOK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Binding constant for full-length AURKC	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P15735	RO:0002436	drug_central	Binding constant for PHKG2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9HCP0	RO:0002436	drug_central	Binding constant for CSNK1G1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central	Binding constant for TRKA kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	Binding constant for FGFR1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Average Binding Constant for FGFR2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13464	RO:0002436	drug_central	Binding affinity to ROCK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P51812	RO:0002436	drug_central	Average Binding Constant for RPS6KA3 (Kin.Dom. 1); NA=Not Active at 10 uM	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O14578	RO:0002436	drug_central	Binding constant for CIT kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8NEV4	RO:0002436	drug_central	Binding constant for MYO3A kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding affinity to HIPK4	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8NFD2	RO:0002436	drug_central	Binding constant for ANKK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O00506	RO:0002436	drug_central	Binding constant for YSK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q15746	RO:0002436	drug_central	Binding affinity to MLCK	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9Y6R4	RO:0002436	drug_central	Average Binding Constant for MAP3K4; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9Y2H1	RO:0002436	drug_central	Binding constant for NDR2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8N568	RO:0002436	drug_central	Binding constant for DCAMKL2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding affinity to MINK	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8N752	RO:0002436	drug_central	Binding constant for full-length CSNK1A1L	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q5S007	RO:0002436	drug_central	Binding constant for LRRK2(G2019S) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9NQU5	RO:0002436	drug_central	Binding constant for PAK6 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9NWZ3	RO:0002436	drug_central	Binding constant for IRAK4 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(V559D,V654A) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P14616	RO:0002436	drug_central	Binding constant for INSRR kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9P1W9	RO:0002436	drug_central	Average Binding Constant for PIM2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9P286	RO:0002436	drug_central	Binding constant for PAK7/PAK5 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UEE5	RO:0002436	drug_central	Binding constant for DRAK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P08069	RO:0002436	drug_central	Binding constant for IGF1R kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q16584	RO:0002436	drug_central	Binding constant for MLK3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Binding constant for EPHA6 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P42679	RO:0002436	drug_central	Binding constant for CTK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Average Binding Constant for TNIK; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q96RR4	RO:0002436	drug_central	Binding constant for CAMKK2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O75676	RO:0002436	drug_central	Binding constant for RPS6KA4(Kin.Dom.1 - C-terminal) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q96GD4	RO:0002436	drug_central	Binding constant for AURKB kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9HAZ1	RO:0002436	drug_central	Binding constant for CLK4 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9HBH9	RO:0002436	drug_central	Binding constant for MKNK2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UIK4	RO:0002436	drug_central	Binding constant for full-length DAPK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O00238	RO:0002436	drug_central	Binding constant for BMPR1B kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Binding affinity to TYK2(JH2domain-pseudokinase)	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding affinity to IRAK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13043	RO:0002436	drug_central	Binding constant for full-length MST1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13882	RO:0002436	drug_central	Binding constant for BRK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8N5S9	RO:0002436	drug_central	Binding constant for CAMKK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8IU85	RO:0002436	drug_central	Binding constant for CAMK1D kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13188	RO:0002436	drug_central	Binding constant for MST2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q96NX5	RO:0002436	drug_central	Binding constant for CAMK1G kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13131	RO:0002436	drug_central	Binding constant for AMPK-alpha1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P51955	RO:0002436	drug_central	Average Binding Constant for NEK2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q15349	RO:0002436	drug_central	Binding constant for RPS6KA2(Kin.Dom.1 - N-terminal) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P54756	RO:0002436	drug_central	Binding constant for EPHA5 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8IYT8	RO:0002436	drug_central	Binding affinity to ULK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central	Binding constant for EPHB1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q16816	RO:0002436	drug_central	Binding constant for full-length PHKG1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central	Average Binding Constant for ACK1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P42336	RO:0002436	drug_central	Inhibition of recombinant PI3Kalpha by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q00536	RO:0002436	drug_central	Average Binding Constant for PCTK1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q05397	RO:0002436	drug_central	Binding constant for PTK2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P68400	RO:0002436	drug_central	Binding constant for full-length CSNK2A1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P31751	RO:0002436	drug_central	Binding constant for AKT2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central	Binding constant for TRKC kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q15831	RO:0002436	drug_central	Binding constant for full-length LKB1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q15835	RO:0002436	drug_central	Binding affinity to GRK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9Y616	RO:0002436	drug_central	Binding constant for IRAK3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UQM7	RO:0002436	drug_central	Binding constant for CAMK2A kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P32298	RO:0002436	drug_central	Binding affinity to GRK4	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding affinity to MAP3K2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding affinity to ULK3	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9P0L2	RO:0002436	drug_central	Binding constant for MARK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9P289	RO:0002436	drug_central	Binding constant for full-length MST4	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9NYY3	RO:0002436	drug_central	Binding affinity to PLK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13873	RO:0002436	drug_central	Binding constant for BMPR2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q14289	RO:0002436	drug_central	Binding constant for full-length PTK2B	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9NRM7	RO:0002436	drug_central	Binding constant for LATS2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O15111	RO:0002436	drug_central	Binding affinity to IKK-alpha	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9Y463	RO:0002436	drug_central	Binding constant for full-length DYRK1B	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q14164	RO:0002436	drug_central	Binding constant for full-length IKK-epsilon	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13523	RO:0002436	drug_central	Binding constant for PRP4 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9NRH2	RO:0002436	drug_central	Binding constant for SNRK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q6XUX3	RO:0002436	drug_central	Binding constant for RIPK5 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding affinity to EPHB6	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O00329	RO:0002436	drug_central	Inhibition of recombinant PI3Kdelta by radioactive phosphotransfer assay in presence of 10 uM ATP	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for full-length SNF1LK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9H2K8	RO:0002436	drug_central	Binding affinity to TAOK3	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P48729	RO:0002436	drug_central	Binding constant for CSNK1A1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9H2K2	RO:0002436	drug_central	Binding affinity to TNK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P50613	RO:0002436	drug_central	Binding constant for full-length CDK7	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central	Binding affinity to ROCK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9Y6E0	RO:0002436	drug_central	Binding constant for MST3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9Y6M4	RO:0002436	drug_central	Binding constant for full-length CSNK1G3	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P53355	RO:0002436	drug_central	Binding constant for DAPK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P54646	RO:0002436	drug_central	Binding constant for AMPK-alpha2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P35916	RO:0002436	drug_central	Binding affinity to VEGFR3 (unknown origin)	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P0C264	RO:0002436	drug_central	Binding affinity to SgK110	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P57058	RO:0002436	drug_central	Binding affinity to HUNK	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central	Binding constant for DDR2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q00537	RO:0002436	drug_central	Binding constant for full-length PCTK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O43293	RO:0002436	drug_central	Binding constant for DAPK3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O96013	RO:0002436	drug_central	Binding constant for PAK4 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9C098	RO:0002436	drug_central	Binding constant for DCAMKL3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O94921	RO:0002436	drug_central	Binding constant for full-length PFTK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9P2K8	RO:0002436	drug_central	Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13627	RO:0002436	drug_central	Binding affinity to DYRK1A	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q07002	RO:0002436	drug_central	Binding constant for full-length PCTK3	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O95819	RO:0002436	drug_central	Binding constant for MAP4K4 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O95835	RO:0002436	drug_central	Binding constant for LATS1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q06418	RO:0002436	drug_central	Binding constant for TYRO3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P07332	RO:0002436	drug_central	Binding constant for FES kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9H1R3	RO:0002436	drug_central	Binding constant for MYLK2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P80192	RO:0002436	drug_central	Binding constant for MLK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central	Binding constant for LTK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding affinity to YSK4	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P78356	RO:0002436	drug_central	Binding constant for full-length PIP5K2B	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O15530	RO:0002436	drug_central	Binding constant for full-length PDPK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9BZL6	RO:0002436	drug_central	Binding constant for PRKD2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central	Binding constant for TRKB kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P80370	RO:0002436	drug_central	Binding affinity to DLK	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P78362	RO:0002436	drug_central	Binding constant for full-length SRPK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central	Binding constant for full-length MEK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P45985	RO:0002436	drug_central	Binding constant for MEK4 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UKI8	RO:0002436	drug_central	Binding constant for TLK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UPE1	RO:0002436	drug_central	Binding affinity to SRPK3	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P52564	RO:0002436	drug_central	Binding constant for MEK6 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Binding constant for ALK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q12852	RO:0002436	drug_central	Binding constant for DLK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q32MK0	RO:0002436	drug_central	Binding constant for MLCK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13546	RO:0002436	drug_central	Binding constant for RIPK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q99755	RO:0002436	drug_central	Binding constant for full-length PIP5K1A	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding affinity to MAP3K3	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q00535	RO:0002436	drug_central	Binding constant for CDK5 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9BRS2	RO:0002436	drug_central	Binding constant for full-length RIOK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P11802	RO:0002436	drug_central	Binding constant for CDK4-cyclinD3 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9BVS4	RO:0002436	drug_central	Binding affinity to RIOK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P23443	RO:0002436	drug_central	Binding constant for S6K1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O75385	RO:0002436	drug_central	Binding affinity to ULK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9BYT3	RO:0002436	drug_central	Binding constant for full-length STK33	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O96017	RO:0002436	drug_central	Binding affinity to CHEK2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P78368	RO:0002436	drug_central	Binding constant for full-length CSNK1G2	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q9BXA7	RO:0002436	drug_central	Binding constant for full-length TSSK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13557	RO:0002436	drug_central	Binding constant for CAMK2D kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:O14757	RO:0002436	drug_central	Binding constant for CHEK1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P57078	RO:0002436	drug_central	Binding affinity to RIPK4	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q16512	RO:0002436	drug_central	Binding constant for PKN1 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P57059	RO:0002436	drug_central	Binding constant for SNF1LK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P17252	RO:0002436	drug_central	Average Binding Constant for PRKACA; NA=Not Active at 10 uM	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13164	RO:0002436	drug_central	Binding constant for ERK5 kinase domain	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q13470	RO:0002436	drug_central	Binding constant for full-length TNK1	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central		biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:Q15375	RO:0002436	drug_central		biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central	inhibition at physiological ATP concentration	biolink:Association
DrugCentral:2544	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	inhibition at physiological ATP concentration	biolink:Association
DrugCentral:2546	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2546	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2546	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:2548	biolink:molecularly_interacts_with	UniProtKB:P47872	RO:0002436	drug_central		biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central		biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:Q04844	RO:0002436	drug_central	Inhibition of acetylcholinesterase	biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assessed as LDH release after 30 mins	biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:Q13224	RO:0002436	drug_central	Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assessed as LDH release after 30 mins	biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:Q05586	RO:0002436	drug_central	Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release after 30 mins	biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:Q12879	RO:0002436	drug_central	Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release after 30 mins	biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2551	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central		biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:P62942	RO:0002436	drug_central		biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:P48454	RO:0002436	drug_central		biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:P60568	RO:0002436	drug_central		biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:P01579	RO:0002436	drug_central		biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:P05113	RO:0002436	drug_central		biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:Q96AY3	RO:0002436	drug_central		biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:P42345	RO:0002436	drug_central	Inhibitory activity against macrophilin (FKBP-12)	biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:Q15393	RO:0002436	drug_central	Inhibition of SAP130 mediated cell growth in human WiDr cells	biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:Q08209	RO:0002436	drug_central	Binding affinity to protein phosphatase, calcineurin (CN) was determined	biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:Q13451	RO:0002436	drug_central	Binding affinity to human FKBP51 by competitive fluorescence polarization assay	biolink:Association
DrugCentral:2552	biolink:molecularly_interacts_with	UniProtKB:P68106	RO:0002436	drug_central		biolink:Association
DrugCentral:2553	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central	Inhibition of human phosphodiesterase 5	biolink:Association
DrugCentral:2553	biolink:molecularly_interacts_with	UniProtKB:O43924	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:2553	biolink:molecularly_interacts_with	UniProtKB:P16499	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:2553	biolink:molecularly_interacts_with	UniProtKB:P18545	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:2553	biolink:molecularly_interacts_with	UniProtKB:P35913	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:2553	biolink:molecularly_interacts_with	UniProtKB:P51160	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:2553	biolink:molecularly_interacts_with	UniProtKB:Q13956	RO:0002436	drug_central	Inhibition of human phosphodiesterase 6	biolink:Association
DrugCentral:2553	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG channel in HEK293 cells by voltage-clamp method	biolink:Association
DrugCentral:2553	biolink:molecularly_interacts_with	UniProtKB:Q9HCR9	RO:0002436	drug_central	Inhibition of human phosphodiesterase 11	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2556	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2557	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2557	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2558	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2558	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2558	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:2558	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2558	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2558	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2558	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2558	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2558	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2558	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2560	biolink:molecularly_interacts_with	UniProtKB:P34981	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P30411	RO:0002436	drug_central	DRUGMATRIX: Bradykinin B2 radioligand binding (ligand: [3H] Bradykinin)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P41968	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q08209	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Phosphatase, PPP3CA (Calcineurin, PP2B) enzyme inhibition (substrate: DiFMUP)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P62508	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q99527	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Displacement of [2,4,6,7-3H]estradiol from human ERalpha expressed in HeLa cells after 18 hrs by liquid scintillation counting	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation counting	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q9BY08	RO:0002436	drug_central	Binding affinity to emopamil binding protein (unknown origin)	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P11474	RO:0002436	drug_central	Antagonist activity at ERalpha receptor in human MCF7 cells assessed as inhibition of cell growth after 6 days by crystal violet staining method	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central	Binding affinity towards antiestrogen binding site AEBS	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:Q9UBM7	RO:0002436	drug_central	Binding affinity towards antiestrogen binding site AEBS	biolink:Association
DrugCentral:2561	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:2562	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity towards recombinant human Compound at 1 uM was tested for the inhibition of radioligand [3H]8-OH-DPAT binding to recombinant human 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand	biolink:Association
DrugCentral:2562	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Binding affinity against human adrenergic receptor subtype Alpha-2A adrenergic receptor using [3H]rauwolscine as radioligand	biolink:Association
DrugCentral:2562	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity towards recombinant human Dopamine receptor D2L was determined using [3H]spiperone as radioligand	biolink:Association
DrugCentral:2562	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Binding affinity against human adrenergic receptor subtype Alpha-1D adrenergic receptor using [3H]prazosin as radioligand	biolink:Association
DrugCentral:2562	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding affinity against human adrenergic receptor subtype Alpha-1A adrenergic receptor using [3H]prazosin as radioligand	biolink:Association
DrugCentral:2562	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Binding affinity against human adrenergic receptor subtype Alpha-1B adrenergic receptor using [3H]prazosin as radioligand	biolink:Association
DrugCentral:2562	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Binding affinity towards recombinant human Dopamine receptor D3 was determined using [3H]spiperone as radioligand	biolink:Association
DrugCentral:2562	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Binding affinity against human Alpha-2C adrenergic receptor using [3H]rauwolscine as radioligand	biolink:Association
DrugCentral:2562	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	Binding affinity towards recombinant human 5-hydroxytryptamine 7 receptor was determined using [3H]LSD as radioligand	biolink:Association
DrugCentral:2563	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity to 5-hydroxytryptamine 1A receptor was determined	biolink:Association
DrugCentral:2563	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity for DA2 receptor	biolink:Association
DrugCentral:2563	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding affinity to Dopamine receptor D4 was determined	biolink:Association
DrugCentral:2571	biolink:molecularly_interacts_with	UniProtKB:P10826	RO:0002436	drug_central	Activity at human RARbeta ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16 hrs by Gal4 response element-driven luciferase reporter gene assay	biolink:Association
DrugCentral:2571	biolink:molecularly_interacts_with	UniProtKB:P10276	RO:0002436	drug_central	Activity at human RARalpha ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16 hrs by Gal4 response element-driven luciferase reporter gene assay	biolink:Association
DrugCentral:2571	biolink:molecularly_interacts_with	UniProtKB:P13631	RO:0002436	drug_central	Activity at human RARgamma ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16 hrs by Gal4 response element-driven luciferase reporter gene assay	biolink:Association
DrugCentral:2579	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2579	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Binding affinity to human recombinant 5HT3 receptor	biolink:Association
DrugCentral:2579	biolink:molecularly_interacts_with	UniProtKB:Q13639	RO:0002436	drug_central	Binding affinity at 5HT4 receptor	biolink:Association
DrugCentral:2579	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2579	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2580	biolink:molecularly_interacts_with	UniProtKB:P07711	RO:0002436	drug_central	Teicoplanin potently prevents the entrance of 2019-nCoV-Spike-pseudoviruses into the cytoplasm	biolink:Association
DrugCentral:2581	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG by patch-clamp assay	biolink:Association
DrugCentral:2583	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Inhibition of ACE (unknown origin) assessed as 3-Hydroxybutyril-glycil-glycil-glycine conversion to 3-hydroxybutyric acid after 60 mins by WST assay	biolink:Association
DrugCentral:2583	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central	Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting	biolink:Association
DrugCentral:2583	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assay	biolink:Association
DrugCentral:2583	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2583	biolink:molecularly_interacts_with	UniProtKB:P50052	RO:0002436	drug_central	Displacement of [125I]Sar1 Ile8-Ang 2 from angiotensin 2 AT2 receptor after 180 mins by gamma counting	biolink:Association
DrugCentral:2583	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:2585	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:2585	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2585	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2585	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2586	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2590	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094255; PROTEIN FAMILY	biolink:Association
DrugCentral:2590	biolink:molecularly_interacts_with	UniProtKB:O15438	RO:0002436	drug_central		biolink:Association
DrugCentral:2590	biolink:molecularly_interacts_with	UniProtKB:O95255	RO:0002436	drug_central		biolink:Association
DrugCentral:2590	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:2590	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2595	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:2595	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2597	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2597	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2597	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2597	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2597	biolink:molecularly_interacts_with	UniProtKB:Q14534	RO:0002436	drug_central	Inhibitory activity against Candida albicans Squalene Epoxidase	biolink:Association
DrugCentral:2598	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:O00337	RO:0002436	drug_central	DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine)	biolink:Association
DrugCentral:2599	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:O95259	RO:0002436	drug_central		biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P51681	RO:0002436	drug_central	DRUGMATRIX: Chemokine CCR5 radioligand binding (ligand: [125I] MIP-1alpha)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P07900	RO:0002436	drug_central		biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M1	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P51589	RO:0002436	drug_central	Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cells	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Compound is evaluated for in vitro receptor binding affinity against Alpha-1 adrenergic receptor	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Compound is evaluated for in vitro receptor binding affinity against Alpha-1 adrenergic receptor	biolink:Association
DrugCentral:2600	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Compound is evaluated for in vitro receptor binding affinity against Alpha-1 adrenergic receptor	biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2601	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2603	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against IKr potassium channel	biolink:Association
DrugCentral:2605	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2605	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:2606	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central		biolink:Association
DrugCentral:2607	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:2607	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:2607	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of human placental aromatase Cytochrome P450 19A1	biolink:Association
DrugCentral:2607	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand	biolink:Association
DrugCentral:2607	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:2607	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay	biolink:Association
DrugCentral:2607	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:2608	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Mechanism of Action; CHEMBL1871; SINGLE PROTEIN	biolink:Association
DrugCentral:2609	biolink:molecularly_interacts_with	UniProtKB:Q05940	RO:0002436	drug_central		biolink:Association
DrugCentral:2609	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2609	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2609	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2609	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2609	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2609	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2609	biolink:molecularly_interacts_with	UniProtKB:P54219	RO:0002436	drug_central		biolink:Association
DrugCentral:2610	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2610	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:2610	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2610	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:2610	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Inhibition of human NaV1.5 alpha subunit expressed in CHOK1 cells at -90 mV holding potential by patch clamp electrophysiological assay	biolink:Association
DrugCentral:2610	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Displacement of [3H]BTX from human Nav1.7 expressed in human HEK293 cells after 1 hr by MicroBeta analyzer	biolink:Association
DrugCentral:2610	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2610	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2610	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2610	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of human NaV1.2 alpha subunit expressed in CHOK1 cells at -65 mV holding potential by patch clamp electrophysiological assay	biolink:Association
DrugCentral:2612	biolink:molecularly_interacts_with	UniProtKB:P00439	RO:0002436	drug_central	Binding affinity for human PAH.	biolink:Association
DrugCentral:2612	biolink:molecularly_interacts_with	UniProtKB:P29475	RO:0002436	drug_central	Activity of tetrahydrobiopterin free nNOS	biolink:Association
DrugCentral:2616	biolink:molecularly_interacts_with	UniProtKB:Q96SW2	RO:0002436	drug_central	competitive titration of thalidomide with human DDB1-human CRBN (50 nM) and Cy5-thalidomide (20 nM)	biolink:Association
DrugCentral:2616	biolink:molecularly_interacts_with	UniProtKB:P01375	RO:0002436	drug_central		biolink:Association
DrugCentral:2616	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2616	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2620	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central		biolink:Association
DrugCentral:2620	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central		biolink:Association
DrugCentral:2620	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central	Displacement of [3H]DPCPX from human recombinant adenosine A2B receptor expressed in HEK293 cell membrane	biolink:Association
DrugCentral:2620	biolink:molecularly_interacts_with	UniProtKB:O00329	RO:0002436	drug_central	Inhibition of PI3Kdelta (unknown origin)	biolink:Association
DrugCentral:2620	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Binding affinity for adenosine A3 receptor by displacement of specific binding of [125I]AB-MECA in membranes from CHO-A3 cells	biolink:Association
DrugCentral:2620	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Binding affinity for adenosine A2a receptor by using as [3H]ZM-241385 radioligand in membranes from HEK-A2A cells	biolink:Association
DrugCentral:2620	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	Binding affinity for adenosine A1 receptor by using as [3H]CPX iradioligand n membranes from Chinese hamster ovary cells	biolink:Association
DrugCentral:2620	biolink:molecularly_interacts_with	UniProtKB:P05186	RO:0002436	drug_central	Inhibition of TNSALP	biolink:Association
DrugCentral:2621	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2621	biolink:molecularly_interacts_with	UniProtKB:P50579	RO:0002436	drug_central	Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cells	biolink:Association
DrugCentral:2621	biolink:molecularly_interacts_with	UniProtKB:P53582	RO:0002436	drug_central	Inhibition of human methionine aminopeptidase 1 in presence of Co2+	biolink:Association
DrugCentral:2621	biolink:molecularly_interacts_with	UniProtKB:P62942	RO:0002436	drug_central	Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry	biolink:Association
DrugCentral:2624	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central		biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2626	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2630	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:2632	biolink:molecularly_interacts_with	UniProtKB:P12268	RO:0002436	drug_central		biolink:Association
DrugCentral:2632	biolink:molecularly_interacts_with	UniProtKB:P20839	RO:0002436	drug_central		biolink:Association
DrugCentral:2632	biolink:molecularly_interacts_with	UniProtKB:P47989	RO:0002436	drug_central	Inhibition of human xanthine oxidase	biolink:Association
DrugCentral:2632	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:2632	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2632	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:2632	biolink:molecularly_interacts_with	UniProtKB:P00492	RO:0002436	drug_central		biolink:Association
DrugCentral:2632	biolink:molecularly_interacts_with	UniProtKB:O15439	RO:0002436	drug_central		biolink:Association
DrugCentral:2632	biolink:molecularly_interacts_with	UniProtKB:O15440	RO:0002436	drug_central		biolink:Association
DrugCentral:2633	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2633	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2633	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2635	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2635	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:Q14994	RO:0002436	drug_central		biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P11309	RO:0002436	drug_central	Inhibition of PIM-1 (unknown origin) after 1 hr by HTRF assay	biolink:Association
DrugCentral:2637	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 7 receptor	biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2639	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2646	biolink:molecularly_interacts_with	UniProtKB:P10828	RO:0002436	drug_central		biolink:Association
DrugCentral:2646	biolink:molecularly_interacts_with	UniProtKB:Q9NVV9	RO:0002436	drug_central		biolink:Association
DrugCentral:2646	biolink:molecularly_interacts_with	UniProtKB:P10827	RO:0002436	drug_central		biolink:Association
DrugCentral:2646	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central	Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay	biolink:Association
DrugCentral:2646	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assay	biolink:Association
DrugCentral:2648	biolink:molecularly_interacts_with	UniProtKB:P30531	RO:0002436	drug_central	Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assay	biolink:Association
DrugCentral:2650	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:2651	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2651	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2651	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2651	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2652	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2652	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2655	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2655	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	biolink:Association
DrugCentral:2655	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2655	biolink:molecularly_interacts_with	UniProtKB:P08842	RO:0002436	drug_central		biolink:Association
DrugCentral:2655	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:2655	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:Q9H244	RO:0002436	drug_central		biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:P11509	RO:0002436	drug_central		biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:2657	biolink:molecularly_interacts_with	UniProtKB:P20813	RO:0002436	drug_central		biolink:Association
DrugCentral:2663	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:2666	biolink:molecularly_interacts_with	UniProtKB:P50281	RO:0002436	drug_central	Inhibition of MMP14 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay	biolink:Association
DrugCentral:2666	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central	Inhibition of APMA-activated recombinant human MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay	biolink:Association
DrugCentral:2666	biolink:molecularly_interacts_with	UniProtKB:P22894	RO:0002436	drug_central	Inhibition of MMP8 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay	biolink:Association
DrugCentral:2666	biolink:molecularly_interacts_with	UniProtKB:Q13488	RO:0002436	drug_central		biolink:Association
DrugCentral:2666	biolink:molecularly_interacts_with	UniProtKB:P18031	RO:0002436	drug_central		biolink:Association
DrugCentral:2672	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	CHO-K1 cells stably expressing the human A1AR	biolink:Association
DrugCentral:2675	biolink:molecularly_interacts_with	UniProtKB:P05093	RO:0002436	drug_central	In vitro inhibition of human Cytochrome P450 17A1 activity	biolink:Association
DrugCentral:2677	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2677	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2677	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2677	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2677	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2680	biolink:molecularly_interacts_with	UniProtKB:P05106	RO:0002436	drug_central		biolink:Association
DrugCentral:2680	biolink:molecularly_interacts_with	UniProtKB:P08514	RO:0002436	drug_central		biolink:Association
DrugCentral:2683	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2683	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central	Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2AR	biolink:Association
DrugCentral:2683	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2683	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2686	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2686	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2686	biolink:molecularly_interacts_with	UniProtKB:Q01118	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2686	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2686	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2686	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2686	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2686	biolink:molecularly_interacts_with	UniProtKB:Q9UI33	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2686	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2686	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2694	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	Mechanism of Action; CHEMBL2096972; PROTEIN COMPLEX	biolink:Association
DrugCentral:2694	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	Mechanism of Action; CHEMBL2096972; PROTEIN COMPLEX	biolink:Association
DrugCentral:2695	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2695	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central	Displacement of (S)-4-(2,4-difluorophenyl-3-tritio) -4,5-dihydro-2-oxazolamine from human TAAR1 receptor expressed in HEK293 cells after 90 mins by beta counting analysis	biolink:Association
DrugCentral:2695	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2695	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2695	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2696	biolink:molecularly_interacts_with	UniProtKB:Q09428	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:2696	biolink:molecularly_interacts_with	UniProtKB:Q14654	RO:0002436	drug_central	[86]Rb+ efflux in RINm5F insulinoma cells	biolink:Association
DrugCentral:2697	biolink:molecularly_interacts_with	UniProtKB:Q13118	RO:0002436	drug_central		biolink:Association
DrugCentral:2697	biolink:molecularly_interacts_with	UniProtKB:P21964	RO:0002436	drug_central		biolink:Association
DrugCentral:2697	biolink:molecularly_interacts_with	UniProtKB:Q9HC97	RO:0002436	drug_central		biolink:Association
DrugCentral:2698	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central	Inhibition of human AKR1C3 using S-(+)-1,2,3,4-tetrahydro-1-naphthol as substrate	biolink:Association
DrugCentral:2698	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central		biolink:Association
DrugCentral:2698	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2698	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2698	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central		biolink:Association
DrugCentral:2699	biolink:molecularly_interacts_with	UniProtKB:P10145	RO:0002436	drug_central	Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay	biolink:Association
DrugCentral:2699	biolink:molecularly_interacts_with	UniProtKB:Q04760	RO:0002436	drug_central	Inhibition of glyoxalase 1	biolink:Association
DrugCentral:2699	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central	Inhibition of Homo sapiens (human) aldose reductase	biolink:Association
DrugCentral:2699	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2699	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2701	biolink:molecularly_interacts_with	UniProtKB:P10636	RO:0002436	drug_central	Inhibition of recombinant tau (unknown origin) aggregation	biolink:Association
DrugCentral:2702	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of MAO-A (unknown origin) by luciferase reporter gene assay	biolink:Association
DrugCentral:2702	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Inhibitory concentration for human Monoamine oxidase B	biolink:Association
DrugCentral:2703	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2703	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2704	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central		biolink:Association
DrugCentral:2704	biolink:molecularly_interacts_with	UniProtKB:P14550	RO:0002436	drug_central	Inhibition of N-terminal 6His-tagged human aldehyde reductase expressed in Escherichia coli BL21(DE3) mediated D-glucuronate reduction	biolink:Association
DrugCentral:2704	biolink:molecularly_interacts_with	UniProtKB:O60218	RO:0002436	drug_central	Inhibition of reductase activity of N-terminal 6His-tagged human AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as pyridine-3-aldehyde reduction	biolink:Association
DrugCentral:2705	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Displacement of [3H]N-methyl Scopolamine from human cloned muscarinic M2 receptor expressed in CHO cells	biolink:Association
DrugCentral:2705	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Displacement of [3H]N-methyl Scopolamine from human cloned muscarinic M1 receptor expressed in CHO cells	biolink:Association
DrugCentral:2705	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against potassium channel HERG	biolink:Association
DrugCentral:2705	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Binding affinity to human muscarinic M3 receptor	biolink:Association
DrugCentral:2705	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	Displacement of [3H]N-methyl Scopolamine from human cloned muscarinic M4 receptor expressed in CHO cells	biolink:Association
DrugCentral:2705	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	Displacement of [3H]N-methyl Scopolamine from human cloned muscarinic M5 receptor expressed in CHO cells	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Compound was evaluated for inhibition against human carbonic anhydrase II	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Ki value against human carbonic anhydrase XII (hCA XII)	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase IV (hCAIV)	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant CA13 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5A	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Ki value against human carbonic anhydrase VII	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Compound was evaluated for inhibition against human carbonic anhydrase IX	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Compound was evaluated for inhibition against human carbonic anhydrase I	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibitory activity against human recombinant mitochondrial isozyme CA VB	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of full length human recombinant CA VI	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P42261	RO:0002436	drug_central	Mechanism of Action; CHEMBL2096670; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P42262	RO:0002436	drug_central	Mechanism of Action; CHEMBL2096670; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P42263	RO:0002436	drug_central	Mechanism of Action; CHEMBL2096670; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P48058	RO:0002436	drug_central	Mechanism of Action; CHEMBL2096670; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:P39086	RO:0002436	drug_central	Mechanism of Action; CHEMBL2109241; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:Q13002	RO:0002436	drug_central	Mechanism of Action; CHEMBL2109241; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:Q13003	RO:0002436	drug_central	Mechanism of Action; CHEMBL2109241; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:Q16099	RO:0002436	drug_central	Mechanism of Action; CHEMBL2109241; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2706	biolink:molecularly_interacts_with	UniProtKB:Q16478	RO:0002436	drug_central	Mechanism of Action; CHEMBL2109241; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:Q969P6	RO:0002436	drug_central		biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central		biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:O15439	RO:0002436	drug_central		biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central	Binding affinity to topoisomerase 1	biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:Q16665	RO:0002436	drug_central	Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay	biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2707	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2708	biolink:molecularly_interacts_with	UniProtKB:Q13621	RO:0002436	drug_central		biolink:Association
DrugCentral:2709	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:2709	biolink:molecularly_interacts_with	UniProtKB:P62508	RO:0002436	drug_central		biolink:Association
DrugCentral:2709	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation counting	biolink:Association
DrugCentral:2711	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Displacement of [3H]U69593 form human kappa opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:2711	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Displacement of [3H]Naltrindole form human delta opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:2711	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Displacement of [3H]DAMGO form human mu opioid receptor expressed in CHO cells	biolink:Association
DrugCentral:2711	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Inhibition of reuptake of Norepinephrine	biolink:Association
DrugCentral:2711	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Inhibition of SERT mediated 5-hydroxytryptamine uptake	biolink:Association
DrugCentral:2711	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central		biolink:Association
DrugCentral:2712	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central		biolink:Association
DrugCentral:2713	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central	Binding affinity to human plasma full length Glu-plasminogen K1 domain by surface plasmon resonance analysis	biolink:Association
DrugCentral:2714	biolink:molecularly_interacts_with	UniProtKB:O60760	RO:0002436	drug_central	Inhibition of glutathione-S-transferase activity of prostaglandin D2 synthase	biolink:Association
DrugCentral:2715	biolink:molecularly_interacts_with	UniProtKB:O60341	RO:0002436	drug_central	Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated for 20 mins with substrate measured after 30 mins by AmplexRed based fluorescence quenching assay	biolink:Association
DrugCentral:2715	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Compound was evaluated for inhibition of Microbial tyramine oxidase; irreversible	biolink:Association
DrugCentral:2715	biolink:molecularly_interacts_with	UniProtKB:P11509	RO:0002436	drug_central		biolink:Association
DrugCentral:2715	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2715	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2715	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2715	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of human recombinant MAO-A assessed as kynuramine oxidation to 4-hydroxyquinoline after 40 mins by LC-MS/MS analysis	biolink:Association
DrugCentral:2715	biolink:molecularly_interacts_with	UniProtKB:Q8NB78	RO:0002436	drug_central	Inhibition of recombinant LSD2 (22 to 822 aa) (unknown origin) expressed in Escherichia coli BL21(DE) by fluorescence assay	biolink:Association
DrugCentral:2716	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central	inhibition of [3H]AL-5848 binding to prostaglandin FP receptor	biolink:Association
DrugCentral:2716	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central	inhibition of [3H]AL-5848 binding to prostaglandin EP3 receptor	biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2717	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2720	biolink:molecularly_interacts_with	UniProtKB:P43119	RO:0002436	drug_central		biolink:Association
DrugCentral:2720	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:2720	biolink:molecularly_interacts_with	UniProtKB:P35408	RO:0002436	drug_central		biolink:Association
DrugCentral:2720	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central		biolink:Association
DrugCentral:2720	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central		biolink:Association
DrugCentral:2720	biolink:molecularly_interacts_with	UniProtKB:Q13258	RO:0002436	drug_central		biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P13631	RO:0002436	drug_central		biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P10826	RO:0002436	drug_central		biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P10276	RO:0002436	drug_central		biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P19793	RO:0002436	drug_central	Binding affinity for retinoic acid receptor RAR alpha	biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P28702	RO:0002436	drug_central	Binding affinity for retinoic acid receptor RAR beta	biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P48443	RO:0002436	drug_central	Binding affinity for retinoic acid receptor RAR gamma	biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:Q92781	RO:0002436	drug_central		biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:Q92753	RO:0002436	drug_central		biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central		biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P51449	RO:0002436	drug_central		biolink:Association
DrugCentral:2722	biolink:molecularly_interacts_with	UniProtKB:P35398	RO:0002436	drug_central		biolink:Association
DrugCentral:2723	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2723	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Compound was tested for its intrinsic activity against beta adrenergic receptor of isolated guinea pig atrial pairs	biolink:Association
DrugCentral:2723	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Compound was tested for its intrinsic activity against beta adrenergic receptor of isolated guinea pig atrial pairs	biolink:Association
DrugCentral:2723	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	Compound was tested for its intrinsic activity against beta adrenergic receptor of isolated guinea pig atrial pairs	biolink:Association
DrugCentral:2723	biolink:molecularly_interacts_with	UniProtKB:P21731	RO:0002436	drug_central	Inhibitory concentration against radioligand [3H]SQ-29,548 (5 nM) binding to TP receptors in human platelets	biolink:Association
DrugCentral:2723	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2725	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:2725	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:2725	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:2726	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:2726	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:2727	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:2728	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2728	biolink:molecularly_interacts_with	UniProtKB:P29466	RO:0002436	drug_central	DRUGMATRIX: Protease, Caspase 1 enzyme inhibition (substrate: Ac-YVAD-AMC)	biolink:Association
DrugCentral:2728	biolink:molecularly_interacts_with	UniProtKB:P08311	RO:0002436	drug_central	DRUGMATRIX: Protease, Cathepsin G enzyme inhibition (substrate: Suc-Ala-Ala-Pro-Phe-AMC)	biolink:Association
DrugCentral:2728	biolink:molecularly_interacts_with	UniProtKB:Q13621	RO:0002436	drug_central		biolink:Association
DrugCentral:2728	biolink:molecularly_interacts_with	UniProtKB:P37088	RO:0002436	drug_central	Mechanism of Action; CHEMBL2107836; PROTEIN COMPLEX	biolink:Association
DrugCentral:2728	biolink:molecularly_interacts_with	UniProtKB:P51168	RO:0002436	drug_central	Mechanism of Action; CHEMBL2107836; PROTEIN COMPLEX	biolink:Association
DrugCentral:2728	biolink:molecularly_interacts_with	UniProtKB:P51170	RO:0002436	drug_central	Mechanism of Action; CHEMBL2107836; PROTEIN COMPLEX	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P25105	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:2729	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:P55017	RO:0002436	drug_central		biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human recombinant full length CA2 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human recombinant full length CA4 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant full length CA5A by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant full length CA14 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant full length CA7 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human recombinant full length CA1 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant full length CA5B by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2733	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human recombinant full length CA6 by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2735	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093872; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:2737	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Mechanism of Action; CHEMBL245; SINGLE PROTEIN	biolink:Association
DrugCentral:2737	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Mechanism of Action; CHEMBL216; SINGLE PROTEIN	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2738	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affinity model	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:Q9BY08	RO:0002436	drug_central	Binding affinity to emopamil binding protein (unknown origin)	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P78527	RO:0002436	drug_central	Inhibition of DNA-PK in human U1810 cells after 30 mins	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central	Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P0DP23	RO:0002436	drug_central	Binding affinity to calmodulin	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P0DP24	RO:0002436	drug_central	Binding affinity to calmodulin	biolink:Association
DrugCentral:2740	biolink:molecularly_interacts_with	UniProtKB:P0DP25	RO:0002436	drug_central	Binding affinity to calmodulin	biolink:Association
DrugCentral:2741	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2741	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2741	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2741	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand	biolink:Association
DrugCentral:2741	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central	Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand	biolink:Association
DrugCentral:2742	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2742	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2742	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affinity model	biolink:Association
DrugCentral:2745	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2745	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2745	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Evaluated for its binding affinity at human muscarinic receptor m3 by the displacement of [3H]NMS binding using membranes from transfected chinese hamster ovarian cell	biolink:Association
DrugCentral:2745	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	Evaluated for its binding affinity at human muscarinic receptor m4 by the displacement of [3H]NMS binding using membranes from transfected chinese hamster ovarian cell	biolink:Association
DrugCentral:2745	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	Evaluated for its binding affinity at human muscarinic receptor m5 by the displacement of [3H]NMS binding using membranes from transfected chinese hamster ovarian cell	biolink:Association
DrugCentral:2745	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Evaluated for its binding affinity at human muscarinic receptor m2 by displacement of [3H]NMS binding using membranes from transfected chinese hamster ovarian cell	biolink:Association
DrugCentral:2745	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Evaluated for its binding affinity at human muscarinic receptor m1 by displacement of [3H]NMS binding using membranes in transfected chinese hamster ovarian cell	biolink:Association
DrugCentral:2746	biolink:molecularly_interacts_with	UniProtKB:P26439	RO:0002436	drug_central		biolink:Association
DrugCentral:2749	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action; CHEMBL231; SINGLE PROTEIN	biolink:Association
DrugCentral:2749	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:2751	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central		biolink:Association
DrugCentral:2752	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:2752	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central		biolink:Association
DrugCentral:2752	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central		biolink:Association
DrugCentral:2752	biolink:molecularly_interacts_with	UniProtKB:Q9GZZ6	RO:0002436	drug_central		biolink:Association
DrugCentral:2755	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central	Inhibition of recombinant Dihydrofolate reductase from humans.	biolink:Association
DrugCentral:2755	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2757	biolink:molecularly_interacts_with	UniProtKB:Q05932	RO:0002436	drug_central		biolink:Association
DrugCentral:2757	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central	Inhibition of human recombinant Dihydrofolate reductase enzyme	biolink:Association
DrugCentral:2758	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2758	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2758	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2758	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2758	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2759	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2759	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2759	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:2761	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand	biolink:Association
DrugCentral:2761	biolink:molecularly_interacts_with	UniProtKB:Q15125	RO:0002436	drug_central	Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand	biolink:Association
DrugCentral:2762	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Inhibitory activity against human Histamine H1 receptor	biolink:Association
DrugCentral:2763	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	GRAC: human H1 selective antagonist	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central		biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA))	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P54840	RO:0002436	drug_central		biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central		biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P18031	RO:0002436	drug_central	Inhibition of PTP1B	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Uncompetitive inhibition of human MAOA expressed in Pichia pastoris	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Uncompetitive inhibition of human MAOB expressed in Pichia pastoris	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:P19224	RO:0002436	drug_central	Inhibition of AZT glucuronidation by human recombinant UGT1A6	biolink:Association
DrugCentral:2767	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:2774	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2774	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2774	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2774	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2774	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2774	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2774	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central	Inhibition constant against nicotinic acetylcholine receptor alpha7	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central	In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determined	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central	In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determined	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	In vitro Binding affinity towards alpha-1-beta-1-gamma-delta nAChR was determined	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P07510	RO:0002436	drug_central	In vitro Binding affinity towards alpha-1-beta-1-gamma-delta nAChR was determined	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central	In vitro Binding affinity towards alpha-1-beta-1-gamma-delta nAChR was determined	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central	In vitro Binding affinity towards alpha-1-beta-1-gamma-delta nAChR was determined	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central	In vitro Binding affinity towards alpha-3 (PC12) nAChR was determined	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Inhibition constant against 5-hydroxytryptamine 1A receptor	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:O95264	RO:0002436	drug_central	GRAC: human 5-HT3B selective antagonist	biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:Q13639	RO:0002436	drug_central		biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P23416	RO:0002436	drug_central		biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P48167	RO:0002436	drug_central		biolink:Association
DrugCentral:2775	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:2776	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2776	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2776	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2776	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Mechanism of Action; CHEMBL211; SINGLE PROTEIN	biolink:Association
DrugCentral:2777	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2777	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:2780	biolink:molecularly_interacts_with	UniProtKB:P41180	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q9UGI6	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q92952	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:O95264	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q9H2S1	RO:0002436	drug_central		biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Displacement of [3H]GABA from gamma-aminobutyric-acid A (GABA-A) receptor	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q401N2	RO:0002436	drug_central	GRAC: human ZAC selective agonist	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central	GRAC: human AChR-alpha7 commonly used antagonist	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P07510	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central	Inhibitory activity against nicotinic acetylcholine receptor alpha3-beta4	biolink:Association
DrugCentral:2781	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central	Inhibitory activity against nicotinic acetylcholine receptor alpha3-beta4	biolink:Association
DrugCentral:2782	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2784	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay	biolink:Association
DrugCentral:2784	biolink:molecularly_interacts_with	UniProtKB:P56817	RO:0002436	drug_central	Binding affinity to BACE1 by surface plasmon resonance method	biolink:Association
DrugCentral:2784	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central		biolink:Association
DrugCentral:2787	biolink:molecularly_interacts_with	UniProtKB:P28838	RO:0002436	drug_central	Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney	biolink:Association
DrugCentral:2787	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central	Inhibition of MMP2 after 30 mins	biolink:Association
DrugCentral:2787	biolink:molecularly_interacts_with	UniProtKB:P09960	RO:0002436	drug_central	Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase by Dixon plot analysis	biolink:Association
DrugCentral:2787	biolink:molecularly_interacts_with	UniProtKB:P15144	RO:0002436	drug_central	Inhibition of aminopeptidase N	biolink:Association
DrugCentral:2796	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2796	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:2796	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2796	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2797	biolink:molecularly_interacts_with	UniProtKB:P52895	RO:0002436	drug_central		biolink:Association
DrugCentral:2797	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Mechanism of Action; CHEMBL2047; SINGLE PROTEIN	biolink:Association
DrugCentral:2797	biolink:molecularly_interacts_with	UniProtKB:Q8TDU6	RO:0002436	drug_central		biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibitory activity against cloned human CA12	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase IV (hCAIV)	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant CA13 catalytic domain pre-incubated for 15 mins by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	In vitro inhibitory concentration against Prostaglandin G/H synthase 1 in human whole blood assay	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P00403	RO:0002436	drug_central	Inhibition of human recombinant cyclooxygenase 2	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human recombinant full length CA3 pre-incubated for 15 mins by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant full length CA5A pre-incubated for 15 mins by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant CA14 catalytic domain pre-incubated for 15 mins by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant full length CA7 pre-incubated for 15 mins by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase I (hCA I) by using esterase assay method	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant full length CA5B pre-incubated for 15 mins by stopped-flow CO2 hydration method	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human full length recombinant carbonic anhydrase 6 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central		biolink:Association
DrugCentral:2799	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:2800	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2800	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2800	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2800	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2800	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:2800	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:2800	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2803	biolink:molecularly_interacts_with	UniProtKB:P14550	RO:0002436	drug_central	Inhibition of AK1A1	biolink:Association
DrugCentral:2803	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central	Inhibition of human recombinant HDAC2	biolink:Association
DrugCentral:2803	biolink:molecularly_interacts_with	UniProtKB:P51649	RO:0002436	drug_central	Mechanism of Action; CHEMBL1911; SINGLE PROTEIN	biolink:Association
DrugCentral:2803	biolink:molecularly_interacts_with	UniProtKB:P35504	RO:0002436	drug_central		biolink:Association
DrugCentral:2803	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central		biolink:Association
DrugCentral:2805	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central		biolink:Association
DrugCentral:2806	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central	Inhibition constant against Angiotensin II receptor, type 1 was determined	biolink:Association
DrugCentral:2807	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central	Displacement of [3H]epibatidine from alpha7 nicotinic receptor expressed in human HEK293 cells	biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	Binding affinity to alpha-1-beta-gamma-delta nicotinic receptor	biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:P07510	RO:0002436	drug_central	Binding affinity to alpha-1-beta-gamma-delta nicotinic receptor	biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central	Binding affinity to alpha-1-beta-gamma-delta nicotinic receptor	biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central	Binding affinity to alpha-1-beta-gamma-delta nicotinic receptor	biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:P32297	RO:0002436	drug_central		biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central	Binding affinity to alpha4beta4 nAChR	biolink:Association
DrugCentral:2808	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central	Binding affinity to alpha4beta4 nAChR	biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central		biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:P54750	RO:0002436	drug_central		biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:P16499	RO:0002436	drug_central		biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:O76083	RO:0002436	drug_central	Inhibition of Phosphodiesterase 9	biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of human phosphodiesterase 4	biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibition of human phosphodiesterase 4	biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Inhibition of human phosphodiesterase 4	biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of human phosphodiesterase 4	biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:O00408	RO:0002436	drug_central	Inhibition of PDE2 (unknown origin) using FAM-cGMP and FAM-cAMP as substrate after 60 mins by fluorescence assay	biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Inhibition of human phosphodiesterase 3	biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Inhibition of human phosphodiesterase 3	biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:Q9HCR9	RO:0002436	drug_central	Inhibition of human phosphodiesterase 11	biolink:Association
DrugCentral:2809	biolink:molecularly_interacts_with	UniProtKB:Q9Y233	RO:0002436	drug_central	Inhibitory concentration against human phosphodiesterase 10	biolink:Association
DrugCentral:2810	biolink:molecularly_interacts_with	UniProtKB:P30559	RO:0002436	drug_central	Displacement of [3H]-AVP from human oxytocin receptor expressed in CHO cells after 30 mins	biolink:Association
DrugCentral:2810	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central	Displacement of [3H]AVP from human vasopressin V2 receptor expressed CHO cells after 60 mins	biolink:Association
DrugCentral:2810	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central	Inhibition of human vasopressin V1a receptor expressed in CHO cells by polarisation binding assay using 96-well plate membranes	biolink:Association
DrugCentral:2810	biolink:molecularly_interacts_with	UniProtKB:P47901	RO:0002436	drug_central	Displacement of [3H]-AVP from human vasopressin V1b receptor expressed in CHO cells after 30 mins	biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:P17787	RO:0002436	drug_central		biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:P30926	RO:0002436	drug_central		biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:P43681	RO:0002436	drug_central		biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:P07510	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2811	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central	GRAC: human AChR-alpha1 commonly used antagonist	biolink:Association
DrugCentral:2813	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2813	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2813	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2813	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cells preincubated for 10 mins prior to substrate addition measured after 4 mins by FLIPR assay	biolink:Association
DrugCentral:2813	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2813	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q13698	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q96PR1	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q96RP8	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q16322	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P48051	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q7RTT9	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity model	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central	Inhibition of MRP1 in human 2008/MRP1 cells by Lineweaver-Burke plot analysis	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P22001	RO:0002436	drug_central	Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method	biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:2815	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	Inhibition of testosterone 6&beta;-hydroxylation.	biolink:Association
DrugCentral:2817	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Inhibition of human PDE3B by fluorescence microplate reader	biolink:Association
DrugCentral:2817	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Inhibition of human PDE3A by fluorescence microplate reader	biolink:Association
DrugCentral:2817	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human Potassium channel HERG expressed in mammalian cells	biolink:Association
DrugCentral:2817	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	In vivo inhibition of cyclic AMP phosphodiesterase from human platelets	biolink:Association
DrugCentral:2817	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	In vivo inhibition of cyclic AMP phosphodiesterase from human platelets	biolink:Association
DrugCentral:2817	biolink:molecularly_interacts_with	UniProtKB:P55072	RO:0002436	drug_central	Vesnarinone binds to the D1 domain of VCP	biolink:Association
DrugCentral:2818	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central	Inhibition of human DPP4 from human Caco-2 cells	biolink:Association
DrugCentral:2818	biolink:molecularly_interacts_with	UniProtKB:P60891	RO:0002436	drug_central		biolink:Association
DrugCentral:2818	biolink:molecularly_interacts_with	UniProtKB:Q16854	RO:0002436	drug_central		biolink:Association
DrugCentral:2818	biolink:molecularly_interacts_with	UniProtKB:P31350	RO:0002436	drug_central		biolink:Association
DrugCentral:2818	biolink:molecularly_interacts_with	UniProtKB:P23921	RO:0002436	drug_central		biolink:Association
DrugCentral:2818	biolink:molecularly_interacts_with	UniProtKB:P09884	RO:0002436	drug_central		biolink:Association
DrugCentral:2818	biolink:molecularly_interacts_with	UniProtKB:P27707	RO:0002436	drug_central		biolink:Association
DrugCentral:2819	biolink:molecularly_interacts_with	UniProtKB:P80404	RO:0002436	drug_central	Mechanism of Action; CHEMBL2044; SINGLE PROTEIN	biolink:Association
DrugCentral:2820	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT	biolink:Association
DrugCentral:2820	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporter	biolink:Association
DrugCentral:2820	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Equilibrium dissociation constant (KD) for Competitive binding between [3H]- imipramine and the compound at human transporter-hSERT	biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:Q5T3U5	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:2823	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity model	biolink:Association
DrugCentral:2824	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2824	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2824	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2824	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:Q5T3U5	RO:0002436	drug_central		biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:2825	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2826	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:2827	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:2828	biolink:molecularly_interacts_with	UniProtKB:P54750	RO:0002436	drug_central	GRAC: human PDE1A selective inhibitor	biolink:Association
DrugCentral:2828	biolink:molecularly_interacts_with	UniProtKB:Q14123	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:P02753	RO:0002436	drug_central	Binding affinity to His-tagged recombinant human sRBP expressed in Escherichia coli BL21(DE3) assessed as apparent dissociation constant after 5 mins by fluorescence spectrophotometric analysis	biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:P12271	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:P10745	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:P00352	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:O94788	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:P50120	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:Q96R05	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:P82980	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:Q8NBN7	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:Q96NR8	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:Q92781	RO:0002436	drug_central		biolink:Association
DrugCentral:2831	biolink:molecularly_interacts_with	UniProtKB:P09455	RO:0002436	drug_central		biolink:Association
DrugCentral:2832	biolink:molecularly_interacts_with	UniProtKB:P07900	RO:0002436	drug_central	Inhibition of recombinant Homo sapiens (human) Hsp90 alpha ATPase activity assessed as inorganic phosphate release by malachite green colorimetric method	biolink:Association
DrugCentral:2832	biolink:molecularly_interacts_with	UniProtKB:P51854	RO:0002436	drug_central		biolink:Association
DrugCentral:2832	biolink:molecularly_interacts_with	UniProtKB:Q9BU02	RO:0002436	drug_central		biolink:Association
DrugCentral:2832	biolink:molecularly_interacts_with	UniProtKB:Q9H3S4	RO:0002436	drug_central		biolink:Association
DrugCentral:2832	biolink:molecularly_interacts_with	UniProtKB:P29401	RO:0002436	drug_central		biolink:Association
DrugCentral:2832	biolink:molecularly_interacts_with	UniProtKB:O60779	RO:0002436	drug_central		biolink:Association
DrugCentral:2834	biolink:molecularly_interacts_with	UniProtKB:Q969G6	RO:0002436	drug_central		biolink:Association
DrugCentral:2834	biolink:molecularly_interacts_with	UniProtKB:P30043	RO:0002436	drug_central		biolink:Association
DrugCentral:2835	biolink:molecularly_interacts_with	UniProtKB:Q8TDS4	RO:0002436	drug_central	Displacement of [3H]nicotinic acid from human GPR109a receptor expressed in CHO cells	biolink:Association
DrugCentral:2835	biolink:molecularly_interacts_with	UniProtKB:P43490	RO:0002436	drug_central		biolink:Association
DrugCentral:2835	biolink:molecularly_interacts_with	UniProtKB:Q15274	RO:0002436	drug_central		biolink:Association
DrugCentral:2835	biolink:molecularly_interacts_with	UniProtKB:P40261	RO:0002436	drug_central		biolink:Association
DrugCentral:2835	biolink:molecularly_interacts_with	UniProtKB:P49019	RO:0002436	drug_central		biolink:Association
DrugCentral:2836	biolink:molecularly_interacts_with	UniProtKB:Q9Y617	RO:0002436	drug_central		biolink:Association
DrugCentral:2836	biolink:molecularly_interacts_with	UniProtKB:P35520	RO:0002436	drug_central		biolink:Association
DrugCentral:2836	biolink:molecularly_interacts_with	UniProtKB:O00764	RO:0002436	drug_central		biolink:Association
DrugCentral:2836	biolink:molecularly_interacts_with	UniProtKB:Q96GD0	RO:0002436	drug_central		biolink:Association
DrugCentral:2836	biolink:molecularly_interacts_with	UniProtKB:Q9NVS9	RO:0002436	drug_central		biolink:Association
DrugCentral:2836	biolink:molecularly_interacts_with	UniProtKB:P34896	RO:0002436	drug_central		biolink:Association
DrugCentral:2838	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central		biolink:Association
DrugCentral:2838	biolink:molecularly_interacts_with	UniProtKB:Q6VVX0	RO:0002436	drug_central		biolink:Association
DrugCentral:2838	biolink:molecularly_interacts_with	UniProtKB:O15528	RO:0002436	drug_central		biolink:Association
DrugCentral:2840	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central	Agonist activity at human VDR expressed in HEK293 cells by luciferase reporter gene assay	biolink:Association
DrugCentral:2840	biolink:molecularly_interacts_with	UniProtKB:Q02318	RO:0002436	drug_central		biolink:Association
DrugCentral:2840	biolink:molecularly_interacts_with	UniProtKB:Q6VVX0	RO:0002436	drug_central		biolink:Association
DrugCentral:2840	biolink:molecularly_interacts_with	UniProtKB:O15528	RO:0002436	drug_central		biolink:Association
DrugCentral:2840	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:2841	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central		biolink:Association
DrugCentral:2845	biolink:molecularly_interacts_with	UniProtKB:P10253	RO:0002436	drug_central	Inhibition of maltase in human Caco-2 cell model system after 2 hrs	biolink:Association
DrugCentral:2846	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:2846	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:2846	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central		biolink:Association
DrugCentral:2847	biolink:molecularly_interacts_with	UniProtKB:Q8N0U8	RO:0002436	drug_central		biolink:Association
DrugCentral:2847	biolink:molecularly_interacts_with	UniProtKB:Q9BQB6	RO:0002436	drug_central		biolink:Association
DrugCentral:2847	biolink:molecularly_interacts_with	UniProtKB:Q16549	RO:0002436	drug_central	Inhibition of recombinant type 8 subtilisin using Arg-Glu-(EDANS)- Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys-(DALBCYL)-Arg fluorogenic substrate preincubated for 1 hr measured after 1 hr at 1 min interval by fluorescence assay	biolink:Association
DrugCentral:2847	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central		biolink:Association
DrugCentral:2847	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:2848	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Antagonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated for 15 mins prior to cimaterol induction measured after 5 hrs	biolink:Association
DrugCentral:2848	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated for 15 mins prior to cimaterol induction measured after 5 hrs	biolink:Association
DrugCentral:2848	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	Antagonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated for 15 mins prior to cimaterol induction measured after 5 hrs	biolink:Association
DrugCentral:2852	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central		biolink:Association
DrugCentral:2852	biolink:molecularly_interacts_with	UniProtKB:P04070	RO:0002436	drug_central	Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotometric analysis	biolink:Association
DrugCentral:2852	biolink:molecularly_interacts_with	UniProtKB:P00750	RO:0002436	drug_central	Inhibition of human t-PA	biolink:Association
DrugCentral:2852	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central	Inhibition of human plasmin	biolink:Association
DrugCentral:2852	biolink:molecularly_interacts_with	UniProtKB:P08709	RO:0002436	drug_central	Inhibition of human coagulation factor 7a using spectrozyme as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotometric analysis in presence of tissue factor	biolink:Association
DrugCentral:2852	biolink:molecularly_interacts_with	UniProtKB:P00742	RO:0002436	drug_central	Inhibition of human factor 10a	biolink:Association
DrugCentral:2852	biolink:molecularly_interacts_with	UniProtKB:P03951	RO:0002436	drug_central	Inhibition of human coagulation factor 11a using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotometric analysis	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:Q15722	RO:0002436	drug_central		biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:Q9NS75	RO:0002436	drug_central		biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:Q9Y271	RO:0002436	drug_central	GRAC: human CysLT1 selective antagonist	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:2855	biolink:molecularly_interacts_with	UniProtKB:P47712	RO:0002436	drug_central	In vitro inhibition of cystolic phospholipase A2 alpha.	biolink:Association
DrugCentral:2856	biolink:molecularly_interacts_with	UniProtKB:P27707	RO:0002436	drug_central		biolink:Association
DrugCentral:2857	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2857	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2857	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2857	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2857	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2857	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:2859	biolink:molecularly_interacts_with	UniProtKB:Q9UQ49	RO:0002436	drug_central	Inhibition of human NEU3 expressed in HEK293 cells by fluorometric high-performance liquid chromatography using ganglioside GM3 substrate	biolink:Association
DrugCentral:2859	biolink:molecularly_interacts_with	UniProtKB:Q9Y3R4	RO:0002436	drug_central	Inhibition of human neuraminidase 2	biolink:Association
DrugCentral:2861	biolink:molecularly_interacts_with	UniProtKB:P04183	RO:0002436	drug_central	Inhibitory affect against rabbit thymus thymidine kinase and represented as molt/4F kinase.	biolink:Association
DrugCentral:2861	biolink:molecularly_interacts_with	UniProtKB:P23919	RO:0002436	drug_central		biolink:Association
DrugCentral:2861	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2861	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:2862	biolink:molecularly_interacts_with	UniProtKB:P34913	RO:0002436	drug_central	Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-oxiraneacetic acid as substrate after 30 mins by fluorescence-based assay	biolink:Association
DrugCentral:2862	biolink:molecularly_interacts_with	UniProtKB:P20292	RO:0002436	drug_central	Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 15 mins by ELISA	biolink:Association
DrugCentral:2862	biolink:molecularly_interacts_with	UniProtKB:Q15722	RO:0002436	drug_central	In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophils	biolink:Association
DrugCentral:2862	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central	Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate after 5 mins by EIA	biolink:Association
DrugCentral:2862	biolink:molecularly_interacts_with	UniProtKB:Q9NS75	RO:0002436	drug_central		biolink:Association
DrugCentral:2862	biolink:molecularly_interacts_with	UniProtKB:P09960	RO:0002436	drug_central		biolink:Association
DrugCentral:2863	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2863	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2863	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Binding affinity against dopamine receptor D1	biolink:Association
DrugCentral:2865	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2866	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Inhibitory activity against angiotensin I converting enzyme (ACE)	biolink:Association
DrugCentral:2868	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	Inhibition of MMP9 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay	biolink:Association
DrugCentral:2868	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central	Inhibition of APMA-activated recombinant human MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay	biolink:Association
DrugCentral:2868	biolink:molecularly_interacts_with	UniProtKB:P14324	RO:0002436	drug_central	Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 mins	biolink:Association
DrugCentral:2868	biolink:molecularly_interacts_with	UniProtKB:P22894	RO:0002436	drug_central	Inhibition of MMP8 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay	biolink:Association
DrugCentral:2868	biolink:molecularly_interacts_with	UniProtKB:O95749	RO:0002436	drug_central	Binding affinity to human GGPPS	biolink:Association
DrugCentral:2868	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2868	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2868	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2868	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:2868	biolink:molecularly_interacts_with	UniProtKB:P50281	RO:0002436	drug_central	Inhibition of MMP14 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay	biolink:Association
DrugCentral:2869	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2869	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2869	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:2869	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2869	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Assay using recombinant GABA<sub>A</sub> channels with subunit composition; &alpha;1&beta;3&gamma;2.	biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Displacement of [3H]Ro-151788 from benzodiazepine binding site of GABAA alpha-2-beta-2-gamma-2 receptor expressed in HEK293T cells	biolink:Association
DrugCentral:2870	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Displacement of [3H]Ro-151788 from benzodiazepine binding site of GABAA alpha-3-beta-2-gamma-2 receptor expressed in HEK293T cells	biolink:Association
DrugCentral:2871	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:2871	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central		biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant CA5A by CO2 hydration assay	biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assay	biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant CA7 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay	biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay	biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of truncated human cloned membrane-associated carbonic anhydrase 4 preincubated for 15 mins by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant CA5B by CO2 hydration assay	biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Competitive inhibition of human MAO B by spectrophotometry	biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant CA13 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human full length recombinant carbonic anhydrase 6 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central		biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central		biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:O43497	RO:0002436	drug_central		biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:2872	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central		biolink:Association
DrugCentral:2873	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 1 receptor	biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity towards human D2 dopamine receptor.	biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Binding affinity against dopamine receptor D1	biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding affinity towards human dopamine-4.2 receptor	biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Binding affinity towards human serotonin 5-hydroxytryptamine 2C receptor	biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Binding affinity towards human serotonin 5-hydroxytryptamine 2A receptor	biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Binding affinity towards human H1 receptor	biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Binding affinity towards human dopamine receptor D3	biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	Binding affinity towards human muscarinic receptor	biolink:Association
DrugCentral:2875	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:2877	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:2877	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:2877	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:2877	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:2877	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation counting	biolink:Association
DrugCentral:2878	biolink:molecularly_interacts_with	UniProtKB:Q00975	RO:0002436	drug_central		biolink:Association
DrugCentral:2949	biolink:molecularly_interacts_with	UniProtKB:P62942	RO:0002436	drug_central		biolink:Association
DrugCentral:2955	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central		biolink:Association
DrugCentral:2955	biolink:molecularly_interacts_with	UniProtKB:P29371	RO:0002436	drug_central	Agonist activity at NK3R (unknown origin) transfected in CHO cells assessed as calcium influx at 10 mM	biolink:Association
DrugCentral:2958	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central	The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone receptor	biolink:Association
DrugCentral:2959	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363078; PROTEIN FAMILY	biolink:Association
DrugCentral:2959	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363078; PROTEIN FAMILY	biolink:Association
DrugCentral:2959	biolink:molecularly_interacts_with	UniProtKB:P47901	RO:0002436	drug_central	Mechanism of Action; CHEMBL2363078; PROTEIN FAMILY	biolink:Association
DrugCentral:2960	biolink:molecularly_interacts_with	UniProtKB:Q9HC29	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q96G91	RO:0002436	drug_central		biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q9BPV8	RO:0002436	drug_central		biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:P47900	RO:0002436	drug_central		biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:P41231	RO:0002436	drug_central		biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q99571	RO:0002436	drug_central		biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:P56373	RO:0002436	drug_central		biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:O94806	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:P05129	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:P05771	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:P17252	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:P24723	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:P41743	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q02156	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q04759	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q05513	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q05655	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q15139	RO:0002436	drug_central	Inhibition of Protein kinase C (PKC)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:P78527	RO:0002436	drug_central	Inhibitory activity against DNA-DNA dependent protein kinase (DNA-PK)	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q9NXA8	RO:0002436	drug_central	Inhibition of human Sirt5 deacetylation activity using FKRGVL-acetylLys-EYGVKV as substrate after 60 mins by glutamate dehydrogenase-coupled assay	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q99873	RO:0002436	drug_central	Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-SAM by scintillation counting	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q8IXJ6	RO:0002436	drug_central	Inhibition of recombinant SIRT2 using ZMAL substrate after 4 hrs by homogeneous fluorescence assay	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q96EB6	RO:0002436	drug_central	Inhibition of recombinant SIRT1 using ZMAL substrate after 4 hrs by homogeneous fluorescence assay	biolink:Association
DrugCentral:2966	biolink:molecularly_interacts_with	UniProtKB:Q15077	RO:0002436	drug_central		biolink:Association
DrugCentral:2968	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central		biolink:Association
DrugCentral:2974	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central		biolink:Association
DrugCentral:2974	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central		biolink:Association
DrugCentral:2974	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central		biolink:Association
DrugCentral:2974	biolink:molecularly_interacts_with	UniProtKB:Q15822	RO:0002436	drug_central		biolink:Association
DrugCentral:2974	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:2975	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central	Mechanism of Action; CHEMBL1855; SINGLE PROTEIN	biolink:Association
DrugCentral:2989	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:2989	biolink:molecularly_interacts_with	UniProtKB:O60894	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:2989	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:2989	biolink:molecularly_interacts_with	UniProtKB:O60895	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:2989	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:2989	biolink:molecularly_interacts_with	UniProtKB:O60896	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:2989	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:2990	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central		biolink:Association
DrugCentral:2994	biolink:molecularly_interacts_with	UniProtKB:P43220	RO:0002436	drug_central		biolink:Association
DrugCentral:2994	biolink:molecularly_interacts_with	UniProtKB:P47871	RO:0002436	drug_central		biolink:Association
DrugCentral:2995	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central		biolink:Association
DrugCentral:2997	biolink:molecularly_interacts_with	UniProtKB:P30874	RO:0002436	drug_central	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-2) subtype	biolink:Association
DrugCentral:2997	biolink:molecularly_interacts_with	UniProtKB:P30872	RO:0002436	drug_central	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	biolink:Association
DrugCentral:2997	biolink:molecularly_interacts_with	UniProtKB:P35346	RO:0002436	drug_central	Inhibition of human sst5 receptor expressed in CHO cells	biolink:Association
DrugCentral:2997	biolink:molecularly_interacts_with	UniProtKB:P32745	RO:0002436	drug_central	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype	biolink:Association
DrugCentral:2997	biolink:molecularly_interacts_with	UniProtKB:P31391	RO:0002436	drug_central	Inhibition of human sst4 receptor expressed in CHO cells	biolink:Association
DrugCentral:3008	biolink:molecularly_interacts_with	UniProtKB:P30559	RO:0002436	drug_central	Binding affinity to human oxytocin receptor	biolink:Association
DrugCentral:3008	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central	Binding affinity to human vasopressin V2 receptor	biolink:Association
DrugCentral:3008	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central	Binding affinity to human vasopressin V1a receptor	biolink:Association
DrugCentral:3008	biolink:molecularly_interacts_with	UniProtKB:P47901	RO:0002436	drug_central	Binding affinity to human vasopressin V1b receptor	biolink:Association
DrugCentral:3016	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central		biolink:Association
DrugCentral:3016	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3016	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3016	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:3018	biolink:molecularly_interacts_with	UniProtKB:Q969F8	RO:0002436	drug_central	Displacement of [125]metastin from metastin receptor	biolink:Association
DrugCentral:3021	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of MAO-A (unknown origin)	biolink:Association
DrugCentral:3025	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Displacement of [3H] N-methylscopolamine from human muscarinic M2 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysis	biolink:Association
DrugCentral:3025	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysis	biolink:Association
DrugCentral:3025	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Displacement of [3H] N-methylscopolamine from human muscarinic M3 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysis	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:O75751	RO:0002436	drug_central	Inhibition of human OCT3-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of human OCT1-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Estrogen Receptor-alpha Coactivator Binding Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 629 (Primary screen preceding this dose response confirmation assay.)]	biolink:Association
DrugCentral:3032	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 633 (Primary screen preceding this dose response confirmation assay.)]	biolink:Association
DrugCentral:3042	biolink:molecularly_interacts_with	UniProtKB:P04183	RO:0002436	drug_central	Binding affinity against HSV-1(KOS) thymidine kinase	biolink:Association
DrugCentral:3047	biolink:molecularly_interacts_with	UniProtKB:Q969S8	RO:0002436	drug_central		biolink:Association
DrugCentral:3047	biolink:molecularly_interacts_with	UniProtKB:Q9UBN7	RO:0002436	drug_central		biolink:Association
DrugCentral:3050	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3050	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3050	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3053	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3053	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3053	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3064	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:3064	biolink:molecularly_interacts_with	UniProtKB:P54577	RO:0002436	drug_central	Compound was tested for the inhibition of aminoacyl tRNA Synthetase	biolink:Association
DrugCentral:3064	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX1	biolink:Association
DrugCentral:3064	biolink:molecularly_interacts_with	UniProtKB:Q8NER1	RO:0002436	drug_central	Binding affinity to human recombinant TRPV1	biolink:Association
DrugCentral:3067	biolink:molecularly_interacts_with	UniProtKB:P05181	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:3068	biolink:molecularly_interacts_with	UniProtKB:P31327	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362990; SINGLE PROTEIN	biolink:Association
DrugCentral:3070	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3070	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3070	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3082	biolink:molecularly_interacts_with	UniProtKB:Q05193	RO:0002436	drug_central	Concentration required against dynamin-1 GTPase activity of sheep brain.	biolink:Association
DrugCentral:3083	biolink:molecularly_interacts_with	UniProtKB:P42575	RO:0002436	drug_central	Activation of procaspase 2 after 24 hrs	biolink:Association
DrugCentral:3094	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:3094	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:3096	biolink:molecularly_interacts_with	UniProtKB:Q8TDU6	RO:0002436	drug_central		biolink:Association
DrugCentral:3101	biolink:molecularly_interacts_with	UniProtKB:Q9Y233	RO:0002436	drug_central	Binding affinity to human PDE10A catalytic domain expressed in Escherichia coli BL21-Gold(DE3) after 15 mins by SPR inhibition in solution assay	biolink:Association
DrugCentral:3114	biolink:molecularly_interacts_with	UniProtKB:P50579	RO:0002436	drug_central	Inhibition of human methionine aminopeptidase 2	biolink:Association
DrugCentral:3114	biolink:molecularly_interacts_with	UniProtKB:P53582	RO:0002436	drug_central	Inhibition of human methionine aminopeptidase 1	biolink:Association
DrugCentral:3123	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3123	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3123	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3135	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:3137	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	compound was tested for inhibitory activity against Thrombin	biolink:Association
DrugCentral:3137	biolink:molecularly_interacts_with	UniProtKB:P00749	RO:0002436	drug_central	compound was tested for inhibitory activity against Urokinase-type plasminogen activator (microPa)	biolink:Association
DrugCentral:3137	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y6	RO:0002436	drug_central	compound was tested for inhibitory activity against Matriptase	biolink:Association
DrugCentral:3142	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:3153	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3153	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3153	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3165	biolink:molecularly_interacts_with	UniProtKB:P21731	RO:0002436	drug_central		biolink:Association
DrugCentral:3170	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:3170	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:3170	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:3170	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:3174	biolink:molecularly_interacts_with	UniProtKB:Q8TDS5	RO:0002436	drug_central	Antagonist activity at human OXE receptor fused with G-alphai assessed as inhibition of 5-oxo-ETE-induced GTPgammaS binding after 60 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:3174	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of aromatase in human placental microsomes by radiometric method	biolink:Association
DrugCentral:3174	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central	Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay	biolink:Association
DrugCentral:3174	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Binding affinity to PPARgamma	biolink:Association
DrugCentral:3174	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Inhibition of PPAR-alpha (unknown origin) by SPA assay	biolink:Association
DrugCentral:3174	biolink:molecularly_interacts_with	UniProtKB:P13726	RO:0002436	drug_central	Inhibition of amidolytic activity of human tissue factor/human factor 7a	biolink:Association
DrugCentral:3177	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central		biolink:Association
DrugCentral:3178	biolink:molecularly_interacts_with	UniProtKB:P18031	RO:0002436	drug_central	Inhibition of recombinant PTP1B	biolink:Association
DrugCentral:3178	biolink:molecularly_interacts_with	UniProtKB:P28845	RO:0002436	drug_central	Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins by scintillation proximity assay	biolink:Association
DrugCentral:3178	biolink:molecularly_interacts_with	UniProtKB:O60218	RO:0002436	drug_central	Inhibition of reductase activity of N-terminal 6His-tagged human AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as pyridine-3-aldehyde reduction	biolink:Association
DrugCentral:3178	biolink:molecularly_interacts_with	UniProtKB:P80365	RO:0002436	drug_central	Inhibition of human 11beta-HSD2	biolink:Association
DrugCentral:3178	biolink:molecularly_interacts_with	UniProtKB:P29350	RO:0002436	drug_central	Inhibition of recombinant SHP1	biolink:Association
DrugCentral:3178	biolink:molecularly_interacts_with	UniProtKB:Q06124	RO:0002436	drug_central	Inhibition of recombinant SHP2	biolink:Association
DrugCentral:3178	biolink:molecularly_interacts_with	UniProtKB:P24723	RO:0002436	drug_central	Binding affinity to recombinant human PKCeta in after 2 hrs by microequilibrium dialysis assay	biolink:Association
DrugCentral:3186	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Ex vivo inhibition of human erythrocyte Acetylcholinesterase.	biolink:Association
DrugCentral:3186	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central	Ex vivo inhibition of human plasma Butyrylcholinesterase.	biolink:Association
DrugCentral:3187	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:3187	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:3187	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:3187	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:3187	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central		biolink:Association
DrugCentral:3187	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:3188	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:3188	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:3188	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Activation of estrogen response element in HeLa cells stably transfected with human Estrogen receptor alpha.	biolink:Association
DrugCentral:3188	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:3188	biolink:molecularly_interacts_with	UniProtKB:P08842	RO:0002436	drug_central	Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 10 mins by fluorescence assay	biolink:Association
DrugCentral:3188	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Activation of estrogen response element in HeLa cells stably transfected with human Estrogen receptor beta.	biolink:Association
DrugCentral:3188	biolink:molecularly_interacts_with	UniProtKB:P14061	RO:0002436	drug_central	Inhibition of 17beta-HSD1 assessed as conversion of [14C]estradiol to [14C]estrone using NADP+	biolink:Association
DrugCentral:3188	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:3194	biolink:molecularly_interacts_with	UniProtKB:O14746	RO:0002436	drug_central	Inhibitory activity against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)	biolink:Association
DrugCentral:3201	biolink:molecularly_interacts_with	UniProtKB:Q16099	RO:0002436	drug_central		biolink:Association
DrugCentral:3201	biolink:molecularly_interacts_with	UniProtKB:P42261	RO:0002436	drug_central	Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 1 in HEK293 cells using [3H]-AMPA as radioligand	biolink:Association
DrugCentral:3201	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:3201	biolink:molecularly_interacts_with	UniProtKB:Q16478	RO:0002436	drug_central	Ability to bind to Ionotropic glutamate receptor kainate (kainate 2) was evaluated.	biolink:Association
DrugCentral:3201	biolink:molecularly_interacts_with	UniProtKB:P48058	RO:0002436	drug_central	Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 4 in HEK293 cells using [3H]AMPA as radioligand	biolink:Association
DrugCentral:3201	biolink:molecularly_interacts_with	UniProtKB:Q13002	RO:0002436	drug_central	Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]kainate as radioligand	biolink:Association
DrugCentral:3201	biolink:molecularly_interacts_with	UniProtKB:P42262	RO:0002436	drug_central	Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 2 in HK293 cells using [3H]AMPA as radioligand	biolink:Association
DrugCentral:3201	biolink:molecularly_interacts_with	UniProtKB:P39086	RO:0002436	drug_central	Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]kainate as radioligand	biolink:Association
DrugCentral:3201	biolink:molecularly_interacts_with	UniProtKB:Q13003	RO:0002436	drug_central	Ability to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluated	biolink:Association
DrugCentral:3201	biolink:molecularly_interacts_with	UniProtKB:P42263	RO:0002436	drug_central		biolink:Association
DrugCentral:3217	biolink:molecularly_interacts_with	UniProtKB:P18031	RO:0002436	drug_central	Inhibition of human PTPase 1B	biolink:Association
DrugCentral:3217	biolink:molecularly_interacts_with	UniProtKB:Q13822	RO:0002436	drug_central	Competitive inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis by Michaelis-Menten method	biolink:Association
DrugCentral:3219	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central	DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1)	biolink:Association
DrugCentral:3219	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:3220	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:3224	biolink:molecularly_interacts_with	UniProtKB:P05121	RO:0002436	drug_central		biolink:Association
DrugCentral:3225	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central		biolink:Association
DrugCentral:3229	biolink:molecularly_interacts_with	UniProtKB:Q9GZT9	RO:0002436	drug_central	Inhibition of 2-oxoglutarate-dependent human recombinant HIF PHD2 preincubated for 1 hr	biolink:Association
DrugCentral:3236	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Ability to induce 50% of maximal effect in rabbit vas deferens expressing Opioid receptor kappa 1	biolink:Association
DrugCentral:3248	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093866; PROTEIN FAMILY	biolink:Association
DrugCentral:3248	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Mechanism of Action; CHEMBL2093866; PROTEIN FAMILY	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3249	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3253	biolink:molecularly_interacts_with	UniProtKB:P50579	RO:0002436	drug_central	Inhibitory activity against Methionine aminopeptidase 2	biolink:Association
DrugCentral:3257	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:3257	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:3257	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:3257	biolink:molecularly_interacts_with	UniProtKB:Q15661	RO:0002436	drug_central		biolink:Association
DrugCentral:3260	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:3260	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:3260	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:3260	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:3260	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central	Inhibition of human recombinant 5-lipoxygenase after 10 mins by fluorescence assay	biolink:Association
DrugCentral:3260	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:3260	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:3275	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	compound was tested for inhibitory activity against Thrombin	biolink:Association
DrugCentral:3275	biolink:molecularly_interacts_with	UniProtKB:P00749	RO:0002436	drug_central	compound was tested for inhibitory activity against Urokinase-type plasminogen activator (microPa)	biolink:Association
DrugCentral:3275	biolink:molecularly_interacts_with	UniProtKB:P07477	RO:0002436	drug_central	Inhibition of trypsin by amidase assay.	biolink:Association
DrugCentral:3275	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y6	RO:0002436	drug_central	compound was tested for inhibitory activity against Matriptase	biolink:Association
DrugCentral:3282	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3282	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3282	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assay	biolink:Association
DrugCentral:3282	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5A by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3282	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 catalytic domain by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3282	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 catalytic domain by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3282	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5B by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3282	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 3 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3282	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay	biolink:Association
DrugCentral:3290	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central	Inhibition of human recombinant MMP2 after 30 mins	biolink:Association
DrugCentral:3290	biolink:molecularly_interacts_with	UniProtKB:P50579	RO:0002436	drug_central	Inhibition of human methionine aminopeptidase 2	biolink:Association
DrugCentral:3290	biolink:molecularly_interacts_with	UniProtKB:P53582	RO:0002436	drug_central	Inhibition of human MetAP1	biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity against sigma receptor using [3H]-( +)-SKF10,047 radioligand	biolink:Association
DrugCentral:3294	biolink:molecularly_interacts_with	UniProtKB:P32239	RO:0002436	drug_central		biolink:Association
DrugCentral:3309	biolink:molecularly_interacts_with	UniProtKB:P05093	RO:0002436	drug_central	In vitro inhibition of human Cytochrome P450 17A1 activity	biolink:Association
DrugCentral:3309	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central		biolink:Association
DrugCentral:3312	biolink:molecularly_interacts_with	UniProtKB:O60741	RO:0002436	drug_central		biolink:Association
DrugCentral:3312	biolink:molecularly_interacts_with	UniProtKB:Q9UL51	RO:0002436	drug_central		biolink:Association
DrugCentral:3312	biolink:molecularly_interacts_with	UniProtKB:Q9P1Z3	RO:0002436	drug_central		biolink:Association
DrugCentral:3312	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central	Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assay	biolink:Association
DrugCentral:3317	biolink:molecularly_interacts_with	UniProtKB:Q96SW2	RO:0002436	drug_central	competitive titration of thalidomide with human DDB1-human CRBN (50 nM) and Cy5-thalidomide (20 nM)	biolink:Association
DrugCentral:3317	biolink:molecularly_interacts_with	UniProtKB:P01375	RO:0002436	drug_central		biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:O14842	RO:0002436	drug_central		biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:Q14721	RO:0002436	drug_central		biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of aromatase in human placental microsomes by radiometric method	biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay	biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central	Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay	biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:P05413	RO:0002436	drug_central	Binding affinity to human FABP3 expressed in Escherichia coli BL21 (DE3) in DMPC liposomes by surface plasmon resonance analysis	biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX1	biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Binding affinity to PPAR-alpha (unknown origin) by fluorescence-based assay	biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:P13726	RO:0002436	drug_central	Inhibition of amidolytic activity of human tissue factor/human factor 7a	biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:P15090	RO:0002436	drug_central	Displacement of 8-anilino-1-naphthalene-sulfonic acid from human His-FABP4 expressed in Escherichia coli BL21 (DE3) cells after 3 mins relative to linoleic acid	biolink:Association
DrugCentral:3323	biolink:molecularly_interacts_with	UniProtKB:Q5NUL3	RO:0002436	drug_central		biolink:Association
DrugCentral:3325	biolink:molecularly_interacts_with	UniProtKB:Q9HC97	RO:0002436	drug_central	GPR35a–beta-arrestin-2 interaction assays performed using a CHO–K1 cell line stably expressing human GPR35 and beta-arrestin-2	biolink:Association
DrugCentral:3341	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:3341	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3342	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:3356	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:3356	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:3356	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	22Rv1 human prostate cells transfected with hAR and luciferase reporter plasmid driven by the androgen response element.	biolink:Association
DrugCentral:3366	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Binding affinity for estrogen receptor of rabbit uterine skeletal muscle tissue	biolink:Association
DrugCentral:3366	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Binding affinity for estrogen receptor of rabbit uterine skeletal muscle tissue	biolink:Association
DrugCentral:3369	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:3369	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:3369	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:3369	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central	Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2AR	biolink:Association
DrugCentral:3377	biolink:molecularly_interacts_with	UniProtKB:P14324	RO:0002436	drug_central	Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 mins	biolink:Association
DrugCentral:3396	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay	biolink:Association
DrugCentral:3396	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central		biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:O14842	RO:0002436	drug_central		biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:O00519	RO:0002436	drug_central	Inhibition of FAAH	biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of aromatase in human placental microsomes by radiometric method	biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay	biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:Q01469	RO:0002436	drug_central	Displacement of 1,8-ANS from eFABP by fluorescence based-assay	biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:P07148	RO:0002436	drug_central	Binding affinity to L-FABP high binding affinity site by titration calorimetry method	biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central	Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay	biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Inhibition of PPAR-alpha (unknown origin) by SPA assay	biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:P13726	RO:0002436	drug_central	Inhibition of amidolytic activity of human tissue factor/human factor 7a	biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:P15090	RO:0002436	drug_central	Displacement of 1,8-ANS from aFABP by fluorescence based-assay	biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central	Inhibition of DNA topoisomerase 1	biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:Q5NUL3	RO:0002436	drug_central		biolink:Association
DrugCentral:3400	biolink:molecularly_interacts_with	UniProtKB:O14746	RO:0002436	drug_central		biolink:Association
DrugCentral:3401	biolink:molecularly_interacts_with	UniProtKB:Q5T6X5	RO:0002436	drug_central		biolink:Association
DrugCentral:3407	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3407	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3407	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:3408	biolink:molecularly_interacts_with	UniProtKB:P14902	RO:0002436	drug_central		biolink:Association
DrugCentral:3413	biolink:molecularly_interacts_with	UniProtKB:Q9Y233	RO:0002436	drug_central	Binding affinity to human PDE10A catalytic domain expressed in Escherichia coli BL21-Gold(DE3) after 15 mins by SPR inhibition in solution assay	biolink:Association
DrugCentral:3413	biolink:molecularly_interacts_with	UniProtKB:Q02127	RO:0002436	drug_central	Inhibition of human recombinant DHOD expressed in Escherichia coli	biolink:Association
DrugCentral:3424	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central		biolink:Association
DrugCentral:3424	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:3424	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:3424	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:3434	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3434	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3434	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Inhibition of human glucocorticoid receptor	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:P68363	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:P68366	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:Q13748	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:Q6PEY2	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:Q71U36	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:Q9BQE3	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3481	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central	In vitro inhibition of mammalian tubulin polymerization by 50%	biolink:Association
DrugCentral:3482	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Mechanism of Action; CHEMBL206; SINGLE PROTEIN	biolink:Association
DrugCentral:3483	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:3486	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:3487	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:3487	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3487	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3487	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3493	biolink:molecularly_interacts_with	UniProtKB:P07477	RO:0002436	drug_central	Inhibition of trypsin by amidase assay.	biolink:Association
DrugCentral:3496	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3496	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3496	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3502	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	Binding affinity at 5HT3 receptor	biolink:Association
DrugCentral:3502	biolink:molecularly_interacts_with	UniProtKB:Q13639	RO:0002436	drug_central	Binding affinity at 5HT4 receptor	biolink:Association
DrugCentral:3502	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:3505	biolink:molecularly_interacts_with	UniProtKB:Q8TDS4	RO:0002436	drug_central		biolink:Association
DrugCentral:3506	biolink:molecularly_interacts_with	UniProtKB:P51575	RO:0002436	drug_central	Antagonist activity at P2X1 receptor (unknown origin)	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 5A preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 6 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 13 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 5B preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:3508	biolink:molecularly_interacts_with	UniProtKB:P55789	RO:0002436	drug_central	PUBCHEM_BIOASSAY: HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488787]	biolink:Association
DrugCentral:3511	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Displacement of [3H]WIN-35428 from human dopamine transporter expressed in mouse N2A cells by scintillation counting	biolink:Association
DrugCentral:3511	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells	biolink:Association
DrugCentral:3511	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cells	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q05397	RO:0002436	drug_central	Inhibition of FAK (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P68400	RO:0002436	drug_central	Inhibitory constant against Zea mays CK2alpha	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q15046	RO:0002436	drug_central	Inhibition of SYK	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Inhibition of recombinant FLT3 (unknown origin) by TR-FRET assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Inhibition of EGFR	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysis	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Displacement of [125I]AB-MECA binding to human Adenosine A3 receptor expressed in HEK293 cells	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P31749	RO:0002436	drug_central	Inhibition of AKT1 (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human CA2 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P00749	RO:0002436	drug_central	Inhibition of urokinase amidolytic activity (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	Binding affinity to ABCB1 nucleotide binding domain 2	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human CA12 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P04054	RO:0002436	drug_central	Inhibition of phospholipase A2	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of VEGFR2 (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Inhibition of SRC (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P04745	RO:0002436	drug_central	Inhibition of human salivary alpha-amylase	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P24941	RO:0002436	drug_central	Inhibition of CDK2	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human CA4 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q9NPH5	RO:0002436	drug_central	Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q00535	RO:0002436	drug_central	Inhibition of Cyclin-dependent kinase 5-p25nck5a	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q15078	RO:0002436	drug_central	Inhibition of Cyclin-dependent kinase 5-p25nck5a	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q99895	RO:0002436	drug_central	Inhibitory activity against chymotrypsinogen	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P11802	RO:0002436	drug_central	Inhibitory activity against cyclin-dependent kinase 4-cyclin D1	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P24385	RO:0002436	drug_central	Inhibitory activity against cyclin-dependent kinase 4-cyclin D1	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q00796	RO:0002436	drug_central	In vitro inhibitory activity against sorbitol dehydrogenase (SD) from sheep liver	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P06493	RO:0002436	drug_central	Inhibition of Cyclin-dependent kinase 1-cyclin B1	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P14635	RO:0002436	drug_central	Inhibition of Cyclin-dependent kinase 1-cyclin B1	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q9NWT6	RO:0002436	drug_central	Inhibition of human recombinant FIH1	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Inhibition of wild type MET (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q00534	RO:0002436	drug_central	Inhibition of human cyclin-dependent kinase 6 complex with a virus-encoded cyclin from herpesvirus saimiri (Vcyclin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central	Inhibition of 5LOX in human PBMC by EIA assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	Inhibition of human recombinant MMP9 catalytic domain incubated for 20 mins by fluorimetric assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of human placental microsome CYP19	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q13554	RO:0002436	drug_central	Inhibition of CAMK2 using autocamtide-2 as substrate after 30 mins by PKLight assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P34913	RO:0002436	drug_central	Inhibition of sEH (unknown origin) assessed as substrate PHOME hydrolysis after 1 hr by fluorescence method	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central	Inhibition of MRP1 transfected in human HeLa cells assessed as inhibition of [3H]LTC4 transport by rapid filtration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P18031	RO:0002436	drug_central	The inhibitory activity tested against human Protein-tyrosine phosphatase 1B enzyme	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Inhibition of human MAOA	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human recombinant AChE by Ellman's method	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Binding affinity to dopamine D4 receptor	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P27986	RO:0002436	drug_central	Inhibition of PI3K	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P17538	RO:0002436	drug_central	Inhibitory activity against Chymotrypsinogen from Thermus flavus	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P53350	RO:0002436	drug_central	Inhibition of PLK1 (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:O60285	RO:0002436	drug_central	Inhibition of ARK5 (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central	Inhibition of human DPP4 using H-Gly-Pro-AMC peptide substrate assessed as increase in fluorescence for 20 mins by fluorimetric assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Inhibition of human MAOB	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P48147	RO:0002436	drug_central	Inhibition of human brain prolyl oligopeptidase expressed in Escherichia coli	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central	Inhibition of vasopressin-stimulated vasopressin V2 receptor in human HTLA cells pre-incubated for 20 mins measured on day 4 by beta arrestin-recruitment mediated luciferase reporter gene assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q9HC97	RO:0002436	drug_central	Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 mins	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition of human recombinant COX2 expressed in insect Sf21 cells by EIA assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P56817	RO:0002436	drug_central	Noncompetitive inhibition of human recombinant BACE1 after 60 mins by Dixon plot analysis	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P0DP23	RO:0002436	drug_central	Inhibition of human recombinant calmodulin assessed as inhibition of calmodulin-sensitive cAMP phosphodiesterase activation after 15 mins by spectrophotometric analysis	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P0DP24	RO:0002436	drug_central	Inhibition of human recombinant calmodulin assessed as inhibition of calmodulin-sensitive cAMP phosphodiesterase activation after 15 mins by spectrophotometric analysis	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P0DP25	RO:0002436	drug_central	Inhibition of human recombinant calmodulin assessed as inhibition of calmodulin-sensitive cAMP phosphodiesterase activation after 15 mins by spectrophotometric analysis	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P08253	RO:0002436	drug_central	Inhibition of human recombinant MMP2 catalytic domain incubated for 20 mins by fluorimetric assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P05164	RO:0002436	drug_central	Inhibition of myeloperoxidase	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P08254	RO:0002436	drug_central	Inhibition of human recombinant MMP3 catalytic domain incubated for 20 mins by fluorimetric assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P06493	RO:0002436	drug_central	Inhibition of CDK1	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q16678	RO:0002436	drug_central	Inhibition of human CYP1B1 by EROD assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P28907	RO:0002436	drug_central	Inhibition of human CD38 using 20 uM 1, N6-etheno NAD+ as substrate by continuous fluorimetric method	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P51679	RO:0002436	drug_central	Inhibition of CCL22-stimulated CCR4 in human HTLA cells pre-incubated for 20 mins measured on day 4 by beta arrestin-recruitment mediated luciferase reporter gene assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P47989	RO:0002436	drug_central	Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometry	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P18054	RO:0002436	drug_central	Inhibition of 12-hLO	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P11309	RO:0002436	drug_central	Binding affinity to non phosphorylated PIM1	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human CA3 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Inhibition of AXL (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P37059	RO:0002436	drug_central	Inhibition of human recombinant 17beta-HSD2 expressed in HEK293 cell lysate assessed as conversion of radiolabeled estrone to estradiol	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P16050	RO:0002436	drug_central	Inhibition of 15-hLO1	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P25024	RO:0002436	drug_central	Inhibition of CX3CL1-stimulated CX3CR1 in human HTLA cells pre-incubated for 20 mins measured on day 4 by beta arrestin-recruitment mediated luciferase reporter gene assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:O95067	RO:0002436	drug_central	Inhibition of cyclin-dependent kinase 1/cyclinB	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P06493	RO:0002436	drug_central	Inhibition of cyclin-dependent kinase 1/cyclinB	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P14635	RO:0002436	drug_central	Inhibition of cyclin-dependent kinase 1/cyclinB	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q8WWL7	RO:0002436	drug_central	Inhibition of cyclin-dependent kinase 1/cyclinB	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human CA5A by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central	Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 staining	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Inhibition of ALK (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human CA14 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human CA7 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human CA9 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human CA1 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P39900	RO:0002436	drug_central	Inhibition of human recombinant MMP12 catalytic domain incubated for 20 mins by fluorimetric assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P08069	RO:0002436	drug_central	Inhibition of IGF1R (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P49841	RO:0002436	drug_central	Inhibition of Homo sapiens (human) recombinant GSK3beta after 30 min by Kinase-Glo assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P06276	RO:0002436	drug_central	Inhibition of human plasma BChE by Ellman's method	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q96GD4	RO:0002436	drug_central	Inhibition of aurora-B (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human CA5B by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q9HC98	RO:0002436	drug_central	Inhibition of NEK6 (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P45452	RO:0002436	drug_central	Inhibition of human recombinant MMP13 catalytic domain incubated for 20 mins by fluorimetric assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q04760	RO:0002436	drug_central	Inhibition of human recombinant His-tagged Glyoxalase 1 expressed in Sf21-Baculovirus system	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P51955	RO:0002436	drug_central	Inhibition of NEK2 (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:Q16512	RO:0002436	drug_central	Inhibition of PRK1 (unknown origin)	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P49840	RO:0002436	drug_central	Inhibition of glycogen synthase kinase 3	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P49841	RO:0002436	drug_central	Inhibition of glycogen synthase kinase 3	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human CA6 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central	Inhibition of cataracted human eye lens aldose reductase	biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P48736	RO:0002436	drug_central		biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P06737	RO:0002436	drug_central		biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P43405	RO:0002436	drug_central		biolink:Association
DrugCentral:3514	biolink:molecularly_interacts_with	UniProtKB:P53355	RO:0002436	drug_central		biolink:Association
DrugCentral:3520	biolink:molecularly_interacts_with	UniProtKB:P02708	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:3520	biolink:molecularly_interacts_with	UniProtKB:P07510	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:3520	biolink:molecularly_interacts_with	UniProtKB:P11230	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:3520	biolink:molecularly_interacts_with	UniProtKB:Q04844	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:3520	biolink:molecularly_interacts_with	UniProtKB:Q07001	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362997; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:3521	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Binding affinity towards monoamine oxidase A activity was measured using a kynuramine assay	biolink:Association
DrugCentral:3521	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Binding affinity towards monoamine oxidase B activity was measured using a benzylamine assay	biolink:Association
DrugCentral:3524	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3524	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5A by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3524	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 catalytic domain by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3524	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 catalytic domain by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3524	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 5B by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:3524	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay	biolink:Association
DrugCentral:3525	biolink:molecularly_interacts_with	UniProtKB:P20648	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3525	biolink:molecularly_interacts_with	UniProtKB:P51164	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3529	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3531	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of human phosphodiesterase 4	biolink:Association
DrugCentral:3531	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibition of human phosphodiesterase 4	biolink:Association
DrugCentral:3531	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Inhibition of human phosphodiesterase 4	biolink:Association
DrugCentral:3531	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of human phosphodiesterase 4	biolink:Association
DrugCentral:3531	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assay	biolink:Association
DrugCentral:3531	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of human full length PDE4A4 expressed in baculovirus infected sf21 cells	biolink:Association
DrugCentral:3531	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibition of human recombinant PDE4B by scintillation proximity assay	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(D835Y) kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(E746-A750del) kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q04759	RO:0002436	drug_central	Binding constant for PRKCQ kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q96SB4	RO:0002436	drug_central	Binding constant for SRPK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O14730	RO:0002436	drug_central	Binding constant for RIOK3 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UK32	RO:0002436	drug_central	Binding constant for RPS6KA6(Kin.Dom.1 - C-terminal) kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q15418	RO:0002436	drug_central	Binding constant for RPS6KA1(Kin.Dom.1 - N-terminal) kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9H422	RO:0002436	drug_central	Binding constant for HIPK3 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O76039	RO:0002436	drug_central	Binding constant for CDKL5 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9H2X6	RO:0002436	drug_central	Binding constant for HIPK2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q86V86	RO:0002436	drug_central	Binding constant for PIM3 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O60285	RO:0002436	drug_central	Binding constant for ARK5 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P41743	RO:0002436	drug_central	Binding constant for PRKCI kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UHD2	RO:0002436	drug_central	Binding constant for TBK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UPZ9	RO:0002436	drug_central	Binding constant for ICK kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for MAP4K1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P17612	RO:0002436	drug_central	Binding constant for PKAC-alpha kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q8TD08	RO:0002436	drug_central	Binding constant for ERK8 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9BUB5	RO:0002436	drug_central	Binding constant for MKNK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q96BR1	RO:0002436	drug_central	Binding constant for SGK3 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P05129	RO:0002436	drug_central	Inhibition of Protein kinase C gamma	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P49760	RO:0002436	drug_central	Binding constant for CLK2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q8WTQ7	RO:0002436	drug_central	Binding constant for GRK7 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q86Z02	RO:0002436	drug_central	Binding constant for HIPK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P49759	RO:0002436	drug_central	Binding constant for full-length CLK1	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13555	RO:0002436	drug_central	Binding constant for CAMK2G kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Average Binding Constant for STK18; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q2M2I8	RO:0002436	drug_central	Binding constant for AAK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q7KZI7	RO:0002436	drug_central	Average Binding Constant for MARK2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q02156	RO:0002436	drug_central	Binding constant for PRKCE kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P19784	RO:0002436	drug_central	Binding constant for full-length CSNK2A2	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O75582	RO:0002436	drug_central	Binding constant for RPS6KA5(Kin.Dom.1 - C-terminal) kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P11309	RO:0002436	drug_central	Competitive binding affinity to PIM1 in presence of ATP	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q16513	RO:0002436	drug_central	Binding constant for PKN2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q7L7X3	RO:0002436	drug_central	Binding constant for TAOK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Average Binding Constant for HCK; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Average Binding Constant for Aurora3; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Average Binding Constant for PDGFRB; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	Average Binding Constant for FGFR1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O14578	RO:0002436	drug_central	Binding constant for CIT kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P51812	RO:0002436	drug_central	Average Binding Constant for RPS6KA3 (Kin.Dom. 1); NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q15746	RO:0002436	drug_central	Binding constant for MYLK kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Average Binding Constant for MAP4K5; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding constant for MINK kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q5S007	RO:0002436	drug_central	Binding constant for LRRK2(G2019S) kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Average Binding Constant for KIT; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9P1W9	RO:0002436	drug_central	Average Binding Constant for PIM2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Average Binding Constant for TNIK; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q96RR4	RO:0002436	drug_central	Average Binding Constant for CAMKK2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O75676	RO:0002436	drug_central	Binding constant for RPS6KA4(Kin.Dom.1 - C-terminal) kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9HAZ1	RO:0002436	drug_central	Binding constant for CLK4 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UIK4	RO:0002436	drug_central	Average Binding Constant for DAPK2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13043	RO:0002436	drug_central	Average Binding Constant for STK4; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q8N5S9	RO:0002436	drug_central	Average Binding Constant for CAMKK1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13188	RO:0002436	drug_central	Binding constant for MST2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q8IU85	RO:0002436	drug_central	Average Binding Constant for CAMK1D; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UL54	RO:0002436	drug_central	Binding constant for TAOK2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q15349	RO:0002436	drug_central	Binding constant for RPS6KA2(Kin.Dom.1 - N-terminal) kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q16816	RO:0002436	drug_central	Average Binding Constant for PHkg1; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q00536	RO:0002436	drug_central	Binding constant for PCTK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P68400	RO:0002436	drug_central	Binding constant for full-length CSNK2A1	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9Y243	RO:0002436	drug_central	Binding constant for AKT3 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P31751	RO:0002436	drug_central	Binding constant for AKT2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q15831	RO:0002436	drug_central	Binding constant for LKB1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q15835	RO:0002436	drug_central	Binding constant for GRK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13554	RO:0002436	drug_central	Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinase	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13555	RO:0002436	drug_central	Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinase	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13557	RO:0002436	drug_central	Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinase	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UQM7	RO:0002436	drug_central	Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinase	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UQM7	RO:0002436	drug_central	Binding constant for CAMK2A kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P32298	RO:0002436	drug_central	Binding constant for GRK4 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding constant for MAP3K2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9NRM7	RO:0002436	drug_central	Binding constant for LATS2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9Y463	RO:0002436	drug_central	Binding constant for full-length DYRK1B	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13523	RO:0002436	drug_central	Binding constant for PRP4 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O60331	RO:0002436	drug_central	Binding constant for PIP5K1C kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P08922	RO:0002436	drug_central	Binding constant for ROS1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9H2K8	RO:0002436	drug_central	Binding constant for TAOK3 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P50613	RO:0002436	drug_central	Binding constant for CDK7 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P53355	RO:0002436	drug_central	Binding constant for DAPK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q05655	RO:0002436	drug_central	Binding constant for PRKCD kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O43293	RO:0002436	drug_central	Average Binding Constant for DAPK3; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13627	RO:0002436	drug_central	Binding constant for DYRK1A kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q09013	RO:0002436	drug_central	Binding constant for DMPK kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O95835	RO:0002436	drug_central	Binding constant for LATS1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Average Binding Constant for LCK; NA=Not Active at 10 uM	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P80192	RO:0002436	drug_central	Binding constant for MLK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P78356	RO:0002436	drug_central	Binding constant for full-length PIP5K2B	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O15530	RO:0002436	drug_central	Binding constant for full-length PDPK1	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9BZL6	RO:0002436	drug_central	Binding constant for PRKD2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P78362	RO:0002436	drug_central	Binding constant for SRPK2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P45985	RO:0002436	drug_central	Binding constant for MEK4 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UKI8	RO:0002436	drug_central	Binding constant for TLK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9UPE1	RO:0002436	drug_central	Binding constant for SRPK3 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P52564	RO:0002436	drug_central	Binding constant for MEK6 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q99755	RO:0002436	drug_central	Binding constant for full-length PIP5K1A	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding constant for MAP3K3 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9BRS2	RO:0002436	drug_central	Binding constant for full-length RIOK1	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P11802	RO:0002436	drug_central	Binding constant for CDK4-cyclinD1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P23443	RO:0002436	drug_central	Binding constant for S6K1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O96017	RO:0002436	drug_central	Binding constant for CHEK2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q9BYT3	RO:0002436	drug_central	Binding constant for STK33 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P49841	RO:0002436	drug_central	Binding constant for full-length GSK3B	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13557	RO:0002436	drug_central	Binding constant for CAMK2D kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:O14757	RO:0002436	drug_central	Binding constant for CHEK1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q13237	RO:0002436	drug_central	Binding constant for PRKG2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P22694	RO:0002436	drug_central	Binding constant for full-length PKAC-beta	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P24723	RO:0002436	drug_central	Binding constant for PRKCH kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q16512	RO:0002436	drug_central	Binding constant for PKN1 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:3533	biolink:molecularly_interacts_with	UniProtKB:P17252	RO:0002436	drug_central	Inhibition of Protein kinase C alpha	biolink:Association
DrugCentral:3534	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:3534	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:3534	biolink:molecularly_interacts_with	UniProtKB:Q01118	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:3534	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:3534	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:3534	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:3534	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:3534	biolink:molecularly_interacts_with	UniProtKB:Q9UI33	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:3534	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:3534	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:3535	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:3535	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Binding affinity to adrenergic alpha2A receptor	biolink:Association
DrugCentral:3535	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of AChE (unknown origin)	biolink:Association
DrugCentral:3535	biolink:molecularly_interacts_with	UniProtKB:P47989	RO:0002436	drug_central	Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometry	biolink:Association
DrugCentral:3535	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Binding affinity to adrenergic alpha2c receptor	biolink:Association
DrugCentral:3535	biolink:molecularly_interacts_with	UniProtKB:P34913	RO:0002436	drug_central	Inhibition of sEH (unknown origin) assessed as substrate PHOME hydrolysis after 1 hr by fluorescence method	biolink:Association
DrugCentral:3535	biolink:molecularly_interacts_with	UniProtKB:Q9GZQ4	RO:0002436	drug_central		biolink:Association
DrugCentral:3536	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:3536	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	In vitro affinity is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor M3	biolink:Association
DrugCentral:3536	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	Partial agonist activity at human M4 receptor co-expressed with Galpha16 in CHO cells assessed as calcium mobilization after 60 mins by FLIPR assay	biolink:Association
DrugCentral:3536	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	In vitro affinity is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor M2	biolink:Association
DrugCentral:3536	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	In vitro affinity against human Muscarinic acetylcholine receptor M1 using quinuclidynyl benzylate (QNB)	biolink:Association
DrugCentral:3542	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central	Binding affinity to human AT1 receptor by radioligand displacement assay	biolink:Association
DrugCentral:3542	biolink:molecularly_interacts_with	UniProtKB:P50052	RO:0002436	drug_central	Displacement of radiolabeled saralasin from human AT2 receptor	biolink:Association
DrugCentral:3548	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central	Binding affinity against human Endothelin A receptor	biolink:Association
DrugCentral:3548	biolink:molecularly_interacts_with	UniProtKB:P24530	RO:0002436	drug_central	In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assay	biolink:Association
DrugCentral:3553	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central	Inhibit supercoil relaxation property of topoisomerase I.	biolink:Association
DrugCentral:3553	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Tested for 50% inhibition of generation of Human estrogen receptor polymerase chain reaction(PCR) products	biolink:Association
DrugCentral:3553	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Tested for 50% inhibition of generation of Human estrogen receptor polymerase chain reaction(PCR) products	biolink:Association
DrugCentral:3553	biolink:molecularly_interacts_with	UniProtKB:P01112	RO:0002436	drug_central	Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) products	biolink:Association
DrugCentral:3574	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central	In vitro inhibition of PDE-V isolated from porcine pulmonary artery.	biolink:Association
DrugCentral:3574	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Concentration of compound required for 50% inhibition of type III cAMP phosphodiesterase from dog ventricles, activity expressed as pIC50	biolink:Association
DrugCentral:3574	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Concentration of compound required for 50% inhibition of type III cAMP phosphodiesterase from dog ventricles, activity expressed as pIC50	biolink:Association
DrugCentral:3577	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Displacement of [3H]8-OH-DPAT from 5HT1A receptor by vacuum filtration	biolink:Association
DrugCentral:3577	biolink:molecularly_interacts_with	UniProtKB:Q9GZQ4	RO:0002436	drug_central		biolink:Association
DrugCentral:3579	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3580	biolink:molecularly_interacts_with	UniProtKB:P10276	RO:0002436	drug_central	Binding affinity for Retinoic Acid Receptor alpha (RAR alpha)	biolink:Association
DrugCentral:3580	biolink:molecularly_interacts_with	UniProtKB:P10826	RO:0002436	drug_central		biolink:Association
DrugCentral:3580	biolink:molecularly_interacts_with	UniProtKB:P13631	RO:0002436	drug_central		biolink:Association
DrugCentral:3584	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:3584	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:3584	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:3584	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:3584	biolink:molecularly_interacts_with	UniProtKB:P16083	RO:0002436	drug_central		biolink:Association
DrugCentral:3584	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:3584	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:3584	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:3584	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:3584	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:3591	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095203; PROTEIN FAMILY	biolink:Association
DrugCentral:3591	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095203; PROTEIN FAMILY	biolink:Association
DrugCentral:3591	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095203; PROTEIN FAMILY	biolink:Association
DrugCentral:3591	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095203; PROTEIN FAMILY	biolink:Association
DrugCentral:3591	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095203; PROTEIN FAMILY	biolink:Association
DrugCentral:3591	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095203; PROTEIN FAMILY	biolink:Association
DrugCentral:3601	biolink:molecularly_interacts_with	UniProtKB:Q99685	RO:0002436	drug_central	Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation counting	biolink:Association
DrugCentral:3601	biolink:molecularly_interacts_with	UniProtKB:O00519	RO:0002436	drug_central	Inhibition of human recombinant FAAH-maltose binding protein	biolink:Association
DrugCentral:3601	biolink:molecularly_interacts_with	UniProtKB:O75936	RO:0002436	drug_central		biolink:Association
DrugCentral:3604	biolink:molecularly_interacts_with	UniProtKB:P12004	RO:0002436	drug_central	Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay	biolink:Association
DrugCentral:3604	biolink:molecularly_interacts_with	UniProtKB:P10827	RO:0002436	drug_central	Concentration required to inhibit 50% of I-T3 binding to hTR1 (Thyroid hormone receptor alpha) was determined	biolink:Association
DrugCentral:3604	biolink:molecularly_interacts_with	UniProtKB:P10828	RO:0002436	drug_central	Concentration required to inhibit 50% of I-T3 binding to hTR1 (Thyroid hormone receptor beta) was determined	biolink:Association
DrugCentral:3607	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 2 assessed as activity of carbonic anhydrase 2 esterase activity against 4-nitrophenyl acetate	biolink:Association
DrugCentral:3609	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:3609	biolink:molecularly_interacts_with	UniProtKB:P07339	RO:0002436	drug_central	Compound was tested for inhibition human Cathepsin D	biolink:Association
DrugCentral:3609	biolink:molecularly_interacts_with	UniProtKB:P0DJD9	RO:0002436	drug_central	Inhibition of human pepsin	biolink:Association
DrugCentral:3609	biolink:molecularly_interacts_with	UniProtKB:P14091	RO:0002436	drug_central	Compound was tested for inhibition human Cathepsin E	biolink:Association
DrugCentral:3611	biolink:molecularly_interacts_with	UniProtKB:P12004	RO:0002436	drug_central	Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay	biolink:Association
DrugCentral:3611	biolink:molecularly_interacts_with	UniProtKB:P10827	RO:0002436	drug_central	Concentration required to inhibit 50% of I-T3 binding to hTR1 (Thyroid hormone receptor alpha) was determined	biolink:Association
DrugCentral:3611	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Transcriptional activity at human androgen receptor BF3 site stably transfected in eGFP-expressing human LNCAP cells after 5 days by fluorometric analysis	biolink:Association
DrugCentral:3611	biolink:molecularly_interacts_with	UniProtKB:P10828	RO:0002436	drug_central	Inhibition of thyroid hormone receptor beta	biolink:Association
DrugCentral:3616	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Binding affinity to beta-1 adrenergic receptor	biolink:Association
DrugCentral:3616	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity to beta2 adrenergic receptor	biolink:Association
DrugCentral:3617	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:3617	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:3617	biolink:molecularly_interacts_with	UniProtKB:Q16850	RO:0002436	drug_central	Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay	biolink:Association
DrugCentral:3620	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:3620	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:3620	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:3630	biolink:molecularly_interacts_with	UniProtKB:P34913	RO:0002436	drug_central	Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate after 10 mins by fluorescent assay	biolink:Association
DrugCentral:3631	biolink:molecularly_interacts_with	UniProtKB:P16152	RO:0002436	drug_central	Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate	biolink:Association
DrugCentral:3639	biolink:molecularly_interacts_with	UniProtKB:P41231	RO:0002436	drug_central		biolink:Association
DrugCentral:3639	biolink:molecularly_interacts_with	UniProtKB:P51582	RO:0002436	drug_central		biolink:Association
DrugCentral:3639	biolink:molecularly_interacts_with	UniProtKB:Q15077	RO:0002436	drug_central		biolink:Association
DrugCentral:3639	biolink:molecularly_interacts_with	UniProtKB:Q96G91	RO:0002436	drug_central		biolink:Association
DrugCentral:3639	biolink:molecularly_interacts_with	UniProtKB:P56373	RO:0002436	drug_central		biolink:Association
DrugCentral:3642	biolink:molecularly_interacts_with	UniProtKB:Q12884	RO:0002436	drug_central	Inhibition of 6xHis-tagged recombinant FAP (unknown origin) expressed in baculovirus expression system assessed as hydrolysis of Nle-Pro-aminomethylcoumarin after 20 mins by fluorometric assay	biolink:Association
DrugCentral:3642	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central	Inhibition of DPP4 in human plasma using Gly-Pro-AMC as substrate by fluorimetric analysis	biolink:Association
DrugCentral:3642	biolink:molecularly_interacts_with	UniProtKB:Q6V1X1	RO:0002436	drug_central	Inhibition of DPP8	biolink:Association
DrugCentral:3642	biolink:molecularly_interacts_with	UniProtKB:Q86TI2	RO:0002436	drug_central	Inhibition of DPP9	biolink:Association
DrugCentral:3643	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:3643	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:3643	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:3643	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:3644	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3644	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3644	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3644	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3644	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3644	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3644	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3644	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3644	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3651	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of human placental microsome CYP19	biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Displacement of [3H]-4-DAMP from human muscarinic M3 receptor expressed in BHK-21 cells	biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	Displacement of [3H]-4-DAMP from human muscarinic M4 receptor expressed in BHK-21 cells	biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	Displacement of [3H]-4-DAMP from human muscarinic M5 receptor expressed in BHK-21 cells	biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Displacement of [3H]-AFDX-384 from human muscarinic M2 receptor expressed in CHO-K1 cells	biolink:Association
DrugCentral:3652	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Affinity towards human M1 receptor expressed in CHO cells using [3H]QNB as radioligand	biolink:Association
DrugCentral:3658	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:3658	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:3658	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:3658	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 1B receptor	biolink:Association
DrugCentral:3658	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central	Binding affinity towards human 5-hydroxytryptamine 1D receptor using [3H]5-HT trifluoroacetate as radioligand	biolink:Association
DrugCentral:3658	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding affinity towards human Alpha-1 adrenergic receptor	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Binding affinity against human Alpha-2A adrenergic receptor expressed stably in CHO cells using [3H]rauwolscine as radioligand	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central	Inhibition of human recombinant DNA topoisomerase1	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Binding affinity against Alpha-1D adrenergic receptor, from human clones.	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Inhibition of specific [3H]prazosin binding (0.2 nM) to rat brain membranes alpha-1 adrenergic receptor	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Binding affinity against Alpha-1B adrenergic receptor from hamster clones.	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P30304	RO:0002436	drug_central	Inhibition of His-tagged Cdc25A expressed in the Escherichia coli BL21(DE3) using p-nitrophenyl phosphate as substrate for 80 mins by spectrophotometry	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Binding affinity against human alpha 2b-adrenergic receptor expressed stably in CHO cells using [3H]rauwolscine as radioligand	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Displacement of [3H]RX821002 from human recombinant alpha2C adrenoceptor expressed in CHO cells	biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:3659	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:3680	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3680	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3680	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3680	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation counting	biolink:Association
DrugCentral:3686	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assay	biolink:Association
DrugCentral:3686	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assay	biolink:Association
DrugCentral:3689	biolink:molecularly_interacts_with	UniProtKB:P47989	RO:0002436	drug_central	Inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 mins by spectrophotometry	biolink:Association
DrugCentral:3707	biolink:molecularly_interacts_with	UniProtKB:P09874	RO:0002436	drug_central	The compound was tested for poly(ADP-ribose)-polymerase (PARP) inhibition	biolink:Association
DrugCentral:3713	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3734	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3734	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3734	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3770	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3770	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3770	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3787	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole)	biolink:Association
DrugCentral:3805	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3805	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3805	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:3839	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central	Compound was tested for inhibition against Angiotensin II receptor, type 1	biolink:Association
DrugCentral:3848	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of acetylcholinesterase (AChE) of human red blood cell (type XIII) by modified radiometric AChE assay	biolink:Association
DrugCentral:3851	biolink:molecularly_interacts_with	UniProtKB:P42330	RO:0002436	drug_central	Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one as substrate after 1 hr by fluorimetric analysis	biolink:Association
DrugCentral:3851	biolink:molecularly_interacts_with	UniProtKB:P52895	RO:0002436	drug_central	Inhibition of human recombinant N-terminal His6-tagged AKR1C2 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one as substrate after 1 hr by fluorimetric analysis	biolink:Association
DrugCentral:3851	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX1 in human HEL 92.1.7 cells assessed as thromboxane B2 production incubated for 30 mins before arachidonic acid addition measured after 15 mins by ELISA	biolink:Association
DrugCentral:3851	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Inhibition of COX2 in LPS-stimulated and PMA-treated human U937 cells assessed as PGE2 production after 15 mins by ELISA	biolink:Association
DrugCentral:3855	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central	Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay	biolink:Association
DrugCentral:3855	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay	biolink:Association
DrugCentral:3855	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay	biolink:Association
DrugCentral:3862	biolink:molecularly_interacts_with	UniProtKB:P13631	RO:0002436	drug_central		biolink:Association
DrugCentral:3862	biolink:molecularly_interacts_with	UniProtKB:P10826	RO:0002436	drug_central		biolink:Association
DrugCentral:3862	biolink:molecularly_interacts_with	UniProtKB:P48443	RO:0002436	drug_central		biolink:Association
DrugCentral:3862	biolink:molecularly_interacts_with	UniProtKB:P28702	RO:0002436	drug_central		biolink:Association
DrugCentral:3862	biolink:molecularly_interacts_with	UniProtKB:P19793	RO:0002436	drug_central		biolink:Association
DrugCentral:3862	biolink:molecularly_interacts_with	UniProtKB:P10276	RO:0002436	drug_central		biolink:Association
DrugCentral:3862	biolink:molecularly_interacts_with	UniProtKB:P51449	RO:0002436	drug_central	Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitment	biolink:Association
DrugCentral:3871	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:3875	biolink:molecularly_interacts_with	UniProtKB:O43193	RO:0002436	drug_central	Compound was tested for in vitro motilin receptor binding affinity	biolink:Association
DrugCentral:3875	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG expressed in HEK cells	biolink:Association
DrugCentral:3880	biolink:molecularly_interacts_with	UniProtKB:O95180	RO:0002436	drug_central	HEK-293 cells stably expressing hCav3.2 T-type Ca2+ channels	biolink:Association
DrugCentral:3880	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3880	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3881	biolink:molecularly_interacts_with	UniProtKB:O75343	RO:0002436	drug_central	The cGMP produced by compound was expressed as a ratio between the percentage of the DEA/NO response for the compound	biolink:Association
DrugCentral:3881	biolink:molecularly_interacts_with	UniProtKB:P33402	RO:0002436	drug_central	The cGMP produced by compound was expressed as a ratio between the percentage of the DEA/NO response for the compound	biolink:Association
DrugCentral:3881	biolink:molecularly_interacts_with	UniProtKB:Q02108	RO:0002436	drug_central	The cGMP produced by compound was expressed as a ratio between the percentage of the DEA/NO response for the compound	biolink:Association
DrugCentral:3881	biolink:molecularly_interacts_with	UniProtKB:Q02153	RO:0002436	drug_central	The cGMP produced by compound was expressed as a ratio between the percentage of the DEA/NO response for the compound	biolink:Association
DrugCentral:3883	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	Ability to compete with [3H]YM-09151-2 binding to the human dopamine receptor D3 transfected in CHO cells	biolink:Association
DrugCentral:3911	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:3912	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:3912	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:3912	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:3912	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Displacement of [3H]prozosin from human cloned dopamine D2 receptor expressed in CHO cells	biolink:Association
DrugCentral:3912	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Displacement of [3H]prozosin from human cloned 5HT2C receptor expressed in CHO cells	biolink:Association
DrugCentral:3912	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Displacement of [3H]prozosin from human cloned histamine H1 receptor expressed in CHO cells	biolink:Association
DrugCentral:3912	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central		biolink:Association
DrugCentral:3920	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 24 hrs	biolink:Association
DrugCentral:3920	biolink:molecularly_interacts_with	UniProtKB:P08235	RO:0002436	drug_central	Displacement of [3H]-aldosterone from human mineralocorticoid receptor expressed in HEK293 cells	biolink:Association
DrugCentral:3920	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central	Displacement of [3H]-methyltrienolone from human progesterone receptor expressed in HEK293 cells	biolink:Association
DrugCentral:3920	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Displacement of [3H]-methyltrienolone from human androgen receptor expressed in HEK293 cells	biolink:Association
DrugCentral:3927	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Competitive inhibition of binding to human placental Cytochrome P450 19A1	biolink:Association
DrugCentral:3927	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:3927	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Displacement of [3H]DHT from human androgen receptor expressed in MDA-MB-453 cells by whole cell receptor binding assay	biolink:Association
DrugCentral:3927	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:3931	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:3931	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:3944	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central	Mechanism of Action; CHEMBL1806; SINGLE PROTEIN	biolink:Association
DrugCentral:3952	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:3952	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:3952	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:3952	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:3952	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:3952	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:3952	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:3952	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:3952	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine)	biolink:Association
DrugCentral:3952	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central	Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2AR	biolink:Association
DrugCentral:3959	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:3961	biolink:molecularly_interacts_with	UniProtKB:P20648	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3961	biolink:molecularly_interacts_with	UniProtKB:P51164	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central		biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:O75311	RO:0002436	drug_central		biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P23416	RO:0002436	drug_central		biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:P48167	RO:0002436	drug_central		biolink:Association
DrugCentral:3972	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assay	biolink:Association
DrugCentral:3977	biolink:molecularly_interacts_with	UniProtKB:P14920	RO:0002436	drug_central	Inhibition of human recombinant DAAO expressed in HEK293 cell lysate assessed as D-Serine conversion to H2O2 after 20 mins by spectrophotometric analysis	biolink:Association
DrugCentral:3977	biolink:molecularly_interacts_with	UniProtKB:P14679	RO:0002436	drug_central	Inhibition of Tyrosinase	biolink:Association
DrugCentral:3995	biolink:molecularly_interacts_with	UniProtKB:O75936	RO:0002436	drug_central	Inhibition of BBOX (unknown origin)	biolink:Association
DrugCentral:4002	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4004	biolink:molecularly_interacts_with	UniProtKB:P47901	RO:0002436	drug_central		biolink:Association
DrugCentral:4004	biolink:molecularly_interacts_with	UniProtKB:P30559	RO:0002436	drug_central	Binding affinity to oxytocin receptor	biolink:Association
DrugCentral:4004	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central	Concentration which inhibit [3H]AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%	biolink:Association
DrugCentral:4004	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central	Binding affinity to vasopressin V1a receptor	biolink:Association
DrugCentral:4006	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:4006	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:4006	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:4050	biolink:molecularly_interacts_with	UniProtKB:Q14832	RO:0002436	drug_central		biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:O00591	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P31644	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P34903	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P78334	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:Q8N1C3	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:Q99928	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:Q9UN88	RO:0002436	drug_central	Binding affinity towards benzodiazepine site in GABAA receptor	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P48147	RO:0002436	drug_central	Inhibition of human brain prolyl oligopeptidase expressed in Escherichia coli	biolink:Association
DrugCentral:4055	biolink:molecularly_interacts_with	UniProtKB:P06493	RO:0002436	drug_central	Inhibition of Cdk1/cyclin B	biolink:Association
DrugCentral:4061	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT)	biolink:Association
DrugCentral:4061	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol)	biolink:Association
DrugCentral:4061	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:4061	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:4063	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:4072	biolink:molecularly_interacts_with	UniProtKB:Q9UHI7	RO:0002436	drug_central		biolink:Association
DrugCentral:4072	biolink:molecularly_interacts_with	UniProtKB:Q9UGH3	RO:0002436	drug_central		biolink:Association
DrugCentral:4072	biolink:molecularly_interacts_with	UniProtKB:Q02809	RO:0002436	drug_central		biolink:Association
DrugCentral:4072	biolink:molecularly_interacts_with	UniProtKB:P13674	RO:0002436	drug_central		biolink:Association
DrugCentral:4072	biolink:molecularly_interacts_with	UniProtKB:P14679	RO:0002436	drug_central		biolink:Association
DrugCentral:4074	biolink:molecularly_interacts_with	UniProtKB:P14324	RO:0002436	drug_central	Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation counting	biolink:Association
DrugCentral:4074	biolink:molecularly_interacts_with	UniProtKB:O95749	RO:0002436	drug_central	Binding affinity to human GGPPS	biolink:Association
DrugCentral:4099	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4099	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4106	biolink:molecularly_interacts_with	UniProtKB:P0DJD9	RO:0002436	drug_central	Mechanism of Action; CHEMBL3295; SINGLE PROTEIN	biolink:Association
DrugCentral:4109	biolink:molecularly_interacts_with	UniProtKB:O75762	RO:0002436	drug_central		biolink:Association
DrugCentral:4109	biolink:molecularly_interacts_with	UniProtKB:Q9Y2T6	RO:0002436	drug_central	Antagonist activity at human GPR55 transfected in CHO cells assessed as inhibition of LPI-induced beta-arrestin recruitment incubated 60 mins prior to LPI addition by beta-arrestin translocation assay	biolink:Association
DrugCentral:4109	biolink:molecularly_interacts_with	UniProtKB:P34972	RO:0002436	drug_central	Binding affinity to human CB2 receptor	biolink:Association
DrugCentral:4109	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central	Binding affinity was determined in vitro against cannabinoid receptor by ability to displace [3H]CP-55940	biolink:Association
DrugCentral:4109	biolink:molecularly_interacts_with	UniProtKB:P34972	RO:0002436	drug_central	Binding affinity was determined in vitro against cannabinoid receptor by ability to displace [3H]CP-55940	biolink:Association
DrugCentral:4109	biolink:molecularly_interacts_with	UniProtKB:Q14330	RO:0002436	drug_central	Agonist activity at human GPR18 expressed in HEK203 cells by MAP kinase assay	biolink:Association
DrugCentral:4109	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central	Displacement of [3H]CP-55940 from human CB1 receptor	biolink:Association
DrugCentral:4109	biolink:molecularly_interacts_with	UniProtKB:P23416	RO:0002436	drug_central		biolink:Association
DrugCentral:4109	biolink:molecularly_interacts_with	UniProtKB:O75311	RO:0002436	drug_central		biolink:Association
DrugCentral:4109	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:4110	biolink:molecularly_interacts_with	UniProtKB:P30518	RO:0002436	drug_central		biolink:Association
DrugCentral:4110	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central		biolink:Association
DrugCentral:4112	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central	Inhibition of human Kv1.5 channel expressed in HEK293 cells by whole cell patch clamp assay	biolink:Association
DrugCentral:4112	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG	biolink:Association
DrugCentral:4112	biolink:molecularly_interacts_with	UniProtKB:O43526	RO:0002436	drug_central		biolink:Association
DrugCentral:4112	biolink:molecularly_interacts_with	UniProtKB:Q06432	RO:0002436	drug_central		biolink:Association
DrugCentral:4112	biolink:molecularly_interacts_with	UniProtKB:Q9NVV9	RO:0002436	drug_central		biolink:Association
DrugCentral:4112	biolink:molecularly_interacts_with	UniProtKB:O60741	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4112	biolink:molecularly_interacts_with	UniProtKB:Q9UL51	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4112	biolink:molecularly_interacts_with	UniProtKB:Q9P1Z3	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4112	biolink:molecularly_interacts_with	UniProtKB:Q9Y3Q4	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4112	biolink:molecularly_interacts_with	UniProtKB:P10827	RO:0002436	drug_central		biolink:Association
DrugCentral:4113	biolink:molecularly_interacts_with	UniProtKB:Q9H244	RO:0002436	drug_central		biolink:Association
DrugCentral:4114	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central	Inhibition of human DPP4 expressed in Caco-2 cells	biolink:Association
DrugCentral:4114	biolink:molecularly_interacts_with	UniProtKB:Q6V1X1	RO:0002436	drug_central	Inhibition of DPP8	biolink:Association
DrugCentral:4114	biolink:molecularly_interacts_with	UniProtKB:Q86TI2	RO:0002436	drug_central	Inhibition of DPP9	biolink:Association
DrugCentral:4114	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:4114	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:4115	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:4117	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central		biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Binding constant for JNK3 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(H396P)-non phosphorylated kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(K663Q) kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9UBF8	RO:0002436	drug_central	Binding constant for PIK4CB kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central	Binding constant for FLT1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Binding constant for VEGFR2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Binding constant for FGFR3(G697C) kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q14012	RO:0002436	drug_central	Binding constant for full-length CAMK1	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P22455	RO:0002436	drug_central	Binding constant for FGFR4 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Binding constant for PDGFRA kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Binding constant for RIPK2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P27448	RO:0002436	drug_central	Binding constant for full-length MARK3	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Binding constant for AURKA kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P43405	RO:0002436	drug_central	Binding constant for SYK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P04049	RO:0002436	drug_central	Binding constant for RAF1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P19525	RO:0002436	drug_central	Binding constant for PRKR kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P21127	RO:0002436	drug_central	Binding constant for CDC2L1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for MAP4K1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P15056	RO:0002436	drug_central	Binding constant for BRAF(V600E) kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P33981	RO:0002436	drug_central	Binding constant for TTK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P16591	RO:0002436	drug_central	Binding constant for FER kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O75716	RO:0002436	drug_central	Binding constant for STK16 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Binding constant for PLK4 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q2M2I8	RO:0002436	drug_central	Binding constant for AAK1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q7L7X3	RO:0002436	drug_central	Binding constant for TAOK1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Binding constant for full-length AURKC	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	Binding constant for FGFR1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Binding constant for FGFR2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q02779	RO:0002436	drug_central	Binding constant for MLK2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q8TBX8	RO:0002436	drug_central	Binding constant for PIP5K2C kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9NRP7	RO:0002436	drug_central	Binding constant for STK36 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(L576P) kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q16584	RO:0002436	drug_central	Binding constant for MLK3 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O00238	RO:0002436	drug_central	Binding constant for BMPR1B kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Binding constant for TYK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q13882	RO:0002436	drug_central	Binding constant for PTK6 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q96NX5	RO:0002436	drug_central	Binding constant for CAMK1G kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9UL54	RO:0002436	drug_central	Binding constant for TAOK2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P51955	RO:0002436	drug_central	Binding constant for NEK2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P53667	RO:0002436	drug_central	Binding constant for full-length LIMK1	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q00536	RO:0002436	drug_central	Binding constant for PCTK1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q6P3R8	RO:0002436	drug_central	Binding constant for NEK5 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9Y616	RO:0002436	drug_central	Binding constant for IRAK3 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding constant for MAP3K2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q13705	RO:0002436	drug_central	Binding constant for ACVR2B kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding constant for TIE2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O60331	RO:0002436	drug_central	Binding constant for PIP5K1C kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P08922	RO:0002436	drug_central	Binding constant for ROS1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P45983	RO:0002436	drug_central	Binding constant for JNK1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for full-length SNF1LK2	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9H2K8	RO:0002436	drug_central	Binding constant for TAOK3 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9H3Y6	RO:0002436	drug_central	Binding constant for SRMS kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q13233	RO:0002436	drug_central	Binding constant for MAP3K1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P35916	RO:0002436	drug_central	Binding constant for FLT4 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central	Binding constant for DDR2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P37173	RO:0002436	drug_central	Binding constant for TGFBR2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(M918T) kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:O95819	RO:0002436	drug_central	Binding constant for MAP4K4 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P07332	RO:0002436	drug_central	Binding constant for FES kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9H1R3	RO:0002436	drug_central	Binding constant for MYLK2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P80192	RO:0002436	drug_central	Binding constant for MLK1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central	Binding constant for LTK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P45985	RO:0002436	drug_central	Binding constant for MEK4 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P52564	RO:0002436	drug_central	Binding constant for MEK6 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P53671	RO:0002436	drug_central	Binding constant for full-length LIMK2	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Binding constant for ALK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q13546	RO:0002436	drug_central	Binding constant for RIPK1 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9UQ88	RO:0002436	drug_central	Binding constant for CDC2L2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9BVS4	RO:0002436	drug_central	Binding constant for RIOK2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q9UBE8	RO:0002436	drug_central	Binding constant for full-length NLK	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:P57059	RO:0002436	drug_central	Binding constant for SNF1LK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q13470	RO:0002436	drug_central	Binding constant for full-length TNK1	biolink:Association
DrugCentral:4118	biolink:molecularly_interacts_with	UniProtKB:Q08881	RO:0002436	drug_central	Mechanism of Action; CHEMBL2959; SINGLE PROTEIN	biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:P56524	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q8WUI4	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q969S8	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q96DB2	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q9BY41	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q9UBN7	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q9UKV0	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q9UQL6	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:P56524	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q8WUI4	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q9UBN7	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q9UKV0	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q9UQL6	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q9BY41	RO:0002436	drug_central		biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central	Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate after 15 to 30 mins	biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:O75376	RO:0002436	drug_central	Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate after 15 to 30 mins	biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central	Inhibition of recombinant human HDAC3/NCOR2 using Boc-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate by two-step fluorogenic assay	biolink:Association
DrugCentral:4119	biolink:molecularly_interacts_with	UniProtKB:Q9Y618	RO:0002436	drug_central	Inhibition of recombinant human HDAC3/NCOR2 using Boc-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate by two-step fluorogenic assay	biolink:Association
DrugCentral:4120	biolink:molecularly_interacts_with	UniProtKB:O00222	RO:0002436	drug_central		biolink:Association
DrugCentral:4120	biolink:molecularly_interacts_with	UniProtKB:O15303	RO:0002436	drug_central		biolink:Association
DrugCentral:4120	biolink:molecularly_interacts_with	UniProtKB:Q14831	RO:0002436	drug_central		biolink:Association
DrugCentral:4120	biolink:molecularly_interacts_with	UniProtKB:Q14833	RO:0002436	drug_central	Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assay	biolink:Association
DrugCentral:4122	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:4122	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:4122	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:4122	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:4122	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:4122	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:4122	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4122	biolink:molecularly_interacts_with	UniProtKB:Q16881	RO:0002436	drug_central		biolink:Association
DrugCentral:4122	biolink:molecularly_interacts_with	UniProtKB:P09917	RO:0002436	drug_central		biolink:Association
DrugCentral:4122	biolink:molecularly_interacts_with	UniProtKB:O75762	RO:0002436	drug_central	Calcium imaging	biolink:Association
DrugCentral:4123	biolink:molecularly_interacts_with	UniProtKB:P51788	RO:0002436	drug_central		biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central	Displacement of fluorescent 5-(3-(3-(4-((4-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)phenylamino)methyl)-1H-1,2,3-triazol-1-yl)propyl)thioureido)-2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid from human HDAC3/NcoR2 by fluorescence polarization assay	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9Y618	RO:0002436	drug_central	Displacement of fluorescent 5-(3-(3-(4-((4-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)phenylamino)methyl)-1H-1,2,3-triazol-1-yl)propyl)thioureido)-2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid from human HDAC3/NcoR2 by fluorescence polarization assay	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q969S8	RO:0002436	drug_central	Inhibition of HDAC10	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q96DB2	RO:0002436	drug_central	Inhibition of recombinant human HDAC11 enzyme using Ac-LeuGlyLys(Ac)-AMC as substrate after 15 to 30 mins	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:P56524	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q8WUI4	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q969S8	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q96DB2	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9BY41	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9UBN7	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9UKV0	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9UQL6	RO:0002436	drug_central	Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9BY41	RO:0002436	drug_central	Competitive inhibition of HDAC8 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central	Inhibition of HDAC1/3/5/8 in human HeLa cell extract using Boc-Lys-(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorometric analysis	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central	Inhibition of HDAC1/3/5/8 in human HeLa cell extract using Boc-Lys-(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorometric analysis	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9BY41	RO:0002436	drug_central	Inhibition of HDAC1/3/5/8 in human HeLa cell extract using Boc-Lys-(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorometric analysis	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9UQL6	RO:0002436	drug_central	Inhibition of HDAC1/3/5/8 in human HeLa cell extract using Boc-Lys-(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorometric analysis	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central	Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate after 15 to 30 mins	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:O75376	RO:0002436	drug_central	Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate after 15 to 30 mins	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:B2RXH2	RO:0002436	drug_central	Inhibition of JMJD2E pre-incubated for 30 mins	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9UKV0	RO:0002436	drug_central	Competitive inhibition of HDAC9 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9UBN7	RO:0002436	drug_central	Displacement of fluorescent 5-(3-(3-(4-((4-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)phenylamino)methyl)-1H-1,2,3-triazol-1-yl)propyl)thioureido)-2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid from human HDAC6 by fluorescence polarization assay	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central	Inhibition of human HDAC1	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:P56524	RO:0002436	drug_central	Inhibition of HDAC4	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central	Inhibition of human HDAC3	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central	Inhibition of human HDAC2	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q9UQL6	RO:0002436	drug_central	Inhibition of HDAC5	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central	Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells.	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central	Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells.	biolink:Association
DrugCentral:4124	biolink:molecularly_interacts_with	UniProtKB:Q8WUI4	RO:0002436	drug_central	Competitive inhibition of HDAC7 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4125	biolink:molecularly_interacts_with	UniProtKB:P12821	RO:0002436	drug_central	Inhibition of ACE (unknown origin) assessed as 3-Hydroxybutyril-glycil-glycil-glycine conversion to 3-hydroxybutyric acid after 60 mins by WST assay	biolink:Association
DrugCentral:4134	biolink:molecularly_interacts_with	UniProtKB:Q06278	RO:0002436	drug_central	Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)	biolink:Association
DrugCentral:4135	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:4135	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Mechanism of Action; CHEMBL222; SINGLE PROTEIN	biolink:Association
DrugCentral:4135	biolink:molecularly_interacts_with	UniProtKB:Q05940	RO:0002436	drug_central	Mechanism of Action; CHEMBL1893; SINGLE PROTEIN	biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:Q9H3N8	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P28566	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P21918	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:4137	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG channel	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine)	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4138	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:4141	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:4141	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central	PDE5 activity in human platelets	biolink:Association
DrugCentral:4142	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Inhibition of aurora kinase A	biolink:Association
DrugCentral:4146	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Displacement of [3H]DHT from human androgen receptor in MDA453 cells	biolink:Association
DrugCentral:4146	biolink:molecularly_interacts_with	UniProtKB:P05093	RO:0002436	drug_central	In vitro cytochrome P450 17A1 inhibition was assayed using the rapid acetic acid releasing assay (AARA), utilizing intact P450c17-expressing Escherichia coli or P450c17-LNCaP cells as the enzyme source.	biolink:Association
DrugCentral:4150	biolink:molecularly_interacts_with	UniProtKB:P21554	RO:0002436	drug_central	Antagonist activity against human CB1 receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assay	biolink:Association
DrugCentral:4150	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human recombinant AChE expressed in HEK293 cells by photometry	biolink:Association
DrugCentral:4150	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG expressed in HEK293 cells assessed as inhibition of potassium channel current after 5 mins by patch clamp assay	biolink:Association
DrugCentral:4150	biolink:molecularly_interacts_with	UniProtKB:Q9Y2T6	RO:0002436	drug_central	Agonist activity at GPR55 (unknown origin) expressed in CHO cells assessed as inhibition of LPI-induced beta-arrestin translocation after 90 mins by luminescence assay	biolink:Association
DrugCentral:4150	biolink:molecularly_interacts_with	UniProtKB:P34972	RO:0002436	drug_central	Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293T cell membranes by scintillation counting	biolink:Association
DrugCentral:4150	biolink:molecularly_interacts_with	UniProtKB:Q14330	RO:0002436	drug_central	Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta9-THC addition by beta-arrestin translocation assay	biolink:Association
DrugCentral:4151	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:4151	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:4151	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:4151	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Binding constant measured against Alpha-1A adrenergic receptor in human prostate; +++:highly active	biolink:Association
DrugCentral:4153	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4153	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4153	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4153	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4153	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4153	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4153	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4153	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4153	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4157	biolink:molecularly_interacts_with	UniProtKB:Q01668	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4157	biolink:molecularly_interacts_with	UniProtKB:Q13936	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4161	biolink:molecularly_interacts_with	UniProtKB:Q00688	RO:0002436	drug_central		biolink:Association
DrugCentral:4161	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:4161	biolink:molecularly_interacts_with	UniProtKB:P42345	RO:0002436	drug_central	Inhibition of FKBP12-independent human recombinant mTOR expressed in HEK293 cells using His6-S6K1 as a substrate by DELFIA assay	biolink:Association
DrugCentral:4161	biolink:molecularly_interacts_with	UniProtKB:P62942	RO:0002436	drug_central	Mechanism of Action; CHEMBL1902; SINGLE PROTEIN	biolink:Association
DrugCentral:4162	biolink:molecularly_interacts_with	UniProtKB:P20648	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095173; PROTEIN COMPLEX	biolink:Association
DrugCentral:4162	biolink:molecularly_interacts_with	UniProtKB:P51164	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095173; PROTEIN COMPLEX	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:O43525	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:O43526	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:O95259	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:P16389	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:P17658	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:P22001	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:P22459	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:P48547	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:P51787	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:P56696	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q03721	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q09470	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q14003	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q14721	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q16322	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q6PIU1	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q8NCM2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q8TAE7	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q8TDN1	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q8TDN2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q92953	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q96KK3	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q96L42	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q96PR1	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q96RP8	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9BQ31	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9H252	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9H3M0	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9NR82	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9NS40	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9NSA2	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9NZV8	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9UIX4	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9UJ96	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9UK17	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9ULD8	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9ULS6	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4163	biolink:molecularly_interacts_with	UniProtKB:Q9UQ05	RO:0002436	drug_central	Mechanism of Action; CHEMBL2362996; PROTEIN FAMILY	biolink:Association
DrugCentral:4164	biolink:molecularly_interacts_with	UniProtKB:P43220	RO:0002436	drug_central		biolink:Association
DrugCentral:4165	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Mechanism of Action; CHEMBL231; SINGLE PROTEIN	biolink:Association
DrugCentral:4166	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:4167	biolink:molecularly_interacts_with	UniProtKB:Q99500	RO:0002436	drug_central	Agonist activity at S1P3 receptor (unknown origin)	biolink:Association
DrugCentral:4167	biolink:molecularly_interacts_with	UniProtKB:Q9H228	RO:0002436	drug_central	Agonist activity at S1P5 receptor (unknown origin)	biolink:Association
DrugCentral:4167	biolink:molecularly_interacts_with	UniProtKB:O95470	RO:0002436	drug_central	Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hr	biolink:Association
DrugCentral:4167	biolink:molecularly_interacts_with	UniProtKB:O95977	RO:0002436	drug_central	Agonist activity at S1P4 receptor (unknown origin)	biolink:Association
DrugCentral:4167	biolink:molecularly_interacts_with	UniProtKB:P21453	RO:0002436	drug_central	Agonist activity at S1P1 receptor (unknown origin)	biolink:Association
DrugCentral:4168	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4168	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4168	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:4168	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	antagonist with moderate affinity	biolink:Association
DrugCentral:4168	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	partial agonist	biolink:Association
DrugCentral:4168	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	antagonist	biolink:Association
DrugCentral:4170	biolink:molecularly_interacts_with	UniProtKB:Q02643	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4171	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central		biolink:Association
DrugCentral:4171	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central		biolink:Association
DrugCentral:4171	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central		biolink:Association
DrugCentral:4171	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central		biolink:Association
DrugCentral:4171	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central		biolink:Association
DrugCentral:4171	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central		biolink:Association
DrugCentral:4171	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central		biolink:Association
DrugCentral:4171	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central		biolink:Association
DrugCentral:4171	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central		biolink:Association
DrugCentral:4172	biolink:molecularly_interacts_with	UniProtKB:P10619	RO:0002436	drug_central		biolink:Association
DrugCentral:4172	biolink:molecularly_interacts_with	UniProtKB:Q9UBX1	RO:0002436	drug_central	Inhibition of human Cathepsin F	biolink:Association
DrugCentral:4172	biolink:molecularly_interacts_with	UniProtKB:P43235	RO:0002436	drug_central	Inhibition of human Cathepsin K	biolink:Association
DrugCentral:4172	biolink:molecularly_interacts_with	UniProtKB:P07858	RO:0002436	drug_central	Inhibition of human CatB after 60 mins fluorescence assay	biolink:Association
DrugCentral:4172	biolink:molecularly_interacts_with	UniProtKB:O60911	RO:0002436	drug_central	Inhibition of human Cathepsin V	biolink:Association
DrugCentral:4172	biolink:molecularly_interacts_with	UniProtKB:P08246	RO:0002436	drug_central	Inhibition of human leukocyte elastase after 60 mins fluorescence assay	biolink:Association
DrugCentral:4172	biolink:molecularly_interacts_with	UniProtKB:P23946	RO:0002436	drug_central	Inhibition of human Chymase	biolink:Association
DrugCentral:4172	biolink:molecularly_interacts_with	UniProtKB:P25774	RO:0002436	drug_central	Inhibition of human Cathepsin S	biolink:Association
DrugCentral:4172	biolink:molecularly_interacts_with	UniProtKB:P07711	RO:0002436	drug_central	Inhibition of human Cathepsin L	biolink:Association
DrugCentral:4173	biolink:molecularly_interacts_with	UniProtKB:P10619	RO:0002436	drug_central		biolink:Association
DrugCentral:4173	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central	Inhibition of human plasmin	biolink:Association
DrugCentral:4173	biolink:molecularly_interacts_with	UniProtKB:P43235	RO:0002436	drug_central	Inhibition of human Cathepsin K	biolink:Association
DrugCentral:4173	biolink:molecularly_interacts_with	UniProtKB:P07858	RO:0002436	drug_central	Inhibition of cathepsin B	biolink:Association
DrugCentral:4173	biolink:molecularly_interacts_with	UniProtKB:O60911	RO:0002436	drug_central	Inhibition of human Cathepsin V	biolink:Association
DrugCentral:4173	biolink:molecularly_interacts_with	UniProtKB:Q9UNI1	RO:0002436	drug_central	Inhibition of human Pancreatic elastase 1	biolink:Association
DrugCentral:4173	biolink:molecularly_interacts_with	UniProtKB:P08246	RO:0002436	drug_central	Inhibition of human leukocyte elastase after 60 mins fluorescence assay	biolink:Association
DrugCentral:4173	biolink:molecularly_interacts_with	UniProtKB:P23946	RO:0002436	drug_central	Inhibition of human Chymase	biolink:Association
DrugCentral:4173	biolink:molecularly_interacts_with	UniProtKB:P25774	RO:0002436	drug_central	Inhibition of human Cathepsin S	biolink:Association
DrugCentral:4173	biolink:molecularly_interacts_with	UniProtKB:P07711	RO:0002436	drug_central	Inhibition of human Cathepsin L	biolink:Association
DrugCentral:4175	biolink:molecularly_interacts_with	UniProtKB:Q12884	RO:0002436	drug_central	Inhibition of FAPalpha	biolink:Association
DrugCentral:4175	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cells	biolink:Association
DrugCentral:4175	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central	Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus system	biolink:Association
DrugCentral:4175	biolink:molecularly_interacts_with	UniProtKB:Q86TI2	RO:0002436	drug_central		biolink:Association
DrugCentral:4176	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	Inhibition of CYP3A4 expressed in baculovirus infected insect microsomes	biolink:Association
DrugCentral:4176	biolink:molecularly_interacts_with	UniProtKB:P15538	RO:0002436	drug_central	Inhibition of human CYP11B1 expressed in hamster V79MZh11B1 cells	biolink:Association
DrugCentral:4176	biolink:molecularly_interacts_with	UniProtKB:P19099	RO:0002436	drug_central	Inhibition of human CYP11B2 expressed in hamster V79MZh11B2 cells	biolink:Association
DrugCentral:4176	biolink:molecularly_interacts_with	UniProtKB:P05093	RO:0002436	drug_central	Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.	biolink:Association
DrugCentral:4177	biolink:molecularly_interacts_with	UniProtKB:P54289	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4177	biolink:molecularly_interacts_with	UniProtKB:Q9NY47	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central	Binding constant for full-length MEK1	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(K663Q) kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(Y253F)-phosphorylated kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(E746-A750del) kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central	Binding constant for FLT1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Average Binding Constant for VEGFR2; NA=Not Active at 10 uM	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Average Binding Constant for FGFR3; NA=Not Active at 10 uM	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q8TDR2	RO:0002436	drug_central	Binding constant for STK35 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P22455	RO:0002436	drug_central	Binding constant for FGFR4 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Binding constant for PDGFRA kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET(Y1235D) kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P49674	RO:0002436	drug_central	Average Binding Constant for CSNK1E; NA=Not Active at 10 uM	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Binding constant for RIPK2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central	Binding constant for EPHB4 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9UK32	RO:0002436	drug_central	Binding constant for RPS6KA6(Kin.Dom.2 - N-terminal) kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q15418	RO:0002436	drug_central	Binding constant for RPS6KA1(Kin.Dom.2 - C-terminal) kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9NYL2	RO:0002436	drug_central	Binding constant for ZAK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central	Binding constant for BTK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P21709	RO:0002436	drug_central	Binding constant for EPHA1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for HPK1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q96D53	RO:0002436	drug_central	Binding constant for full-length ADCK4	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9BUB5	RO:0002436	drug_central	Binding constant for full-length MKNK1	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q5VT25	RO:0002436	drug_central	Binding constant for MRCKA kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P29322	RO:0002436	drug_central	Binding constant for EPHA8 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P29317	RO:0002436	drug_central	Binding constant for EPHA2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Average Binding Constant for EPHA3; NA=Not Active at 10 uM	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Binding constant for PLK4 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central	Binding constant for full-length CSK	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q59H18	RO:0002436	drug_central	Binding constant for full-length TNNI3K	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	Binding constant for ERBB2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Binding constant for full-length AURKC	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P15735	RO:0002436	drug_central	Binding constant for PHKG2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	Binding constant for FGFR1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Binding constant for FGFR2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:O14578	RO:0002436	drug_central	Binding constant for CIT kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q8NI60	RO:0002436	drug_central	Binding constant for ADCK3 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9Y6R4	RO:0002436	drug_central	Binding constant for MAP3K4 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding constant for MINK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9NWZ3	RO:0002436	drug_central	Binding constant for IRAK4 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(A829P) kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central	Binding constant for ERBB4 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Binding constant for EPHA6 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Average Binding Constant for SLK; NA=Not Active at 10 uM	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9HBH9	RO:0002436	drug_central	Binding constant for MKNK2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:O00238	RO:0002436	drug_central	Binding constant for BMPR1B kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q04912	RO:0002436	drug_central	In vitro inhibition of Met proto-oncogene tyrosine kinase (c-Met) expressed in baculovirus	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q15375	RO:0002436	drug_central	Binding constant for EPHA7 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q13882	RO:0002436	drug_central	Average Binding Constant for PTK6; NA=Not Active at 10 uM	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q13131	RO:0002436	drug_central	Binding constant for AMPK-alpha1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P54756	RO:0002436	drug_central	Binding constant for EPHA5 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P54764	RO:0002436	drug_central	Binding constant for EPHA4 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q16816	RO:0002436	drug_central	Binding constant for full-length PHKG1	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central	Binding constant for EPHB1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q15569	RO:0002436	drug_central	Binding constant for TESK1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q04771	RO:0002436	drug_central	Binding constant for ACVR1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q6DT37	RO:0002436	drug_central	Binding constant for DMPK2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9Y5S2	RO:0002436	drug_central	Binding constant for MRCKB kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding constant for ULK3 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding constant for TIE2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P21860	RO:0002436	drug_central	Binding constant for ERBB3 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for full-length SNF1LK2	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9H3Y6	RO:0002436	drug_central	Binding constant for SRMS kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P50613	RO:0002436	drug_central	Binding constant for CDK7 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q8WU08	RO:0002436	drug_central	Binding constant for YANK1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9Y2K2	RO:0002436	drug_central	Binding constant for QSK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central	Binding constant for ROCK2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P35916	RO:0002436	drug_central	Average Binding Constant for FLT4; NA=Not Active at 10 uM	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P57058	RO:0002436	drug_central	Binding constant for HUNK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central	Binding constant for DDR2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q16659	RO:0002436	drug_central	Binding constant for ERK3 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P37023	RO:0002436	drug_central	Binding constant for ACVRL1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(M918T) kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:O95819	RO:0002436	drug_central	Binding constant for MAP4K4 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q06418	RO:0002436	drug_central	Binding constant for TYRO3 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central	Binding constant for LTK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P29323	RO:0002436	drug_central	Binding constant for EPHB2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central	Binding constant for full-length MEK2	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Binding constant for ALK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P23443	RO:0002436	drug_central	Binding constant for S6K1 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q9BYT3	RO:0002436	drug_central	Binding constant for full-length STK33	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P57078	RO:0002436	drug_central	Binding constant for RIPK4 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:P57059	RO:0002436	drug_central	Binding constant for SNF1LK kinase domain	biolink:Association
DrugCentral:4178	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:4181	biolink:molecularly_interacts_with	UniProtKB:O43526	RO:0002436	drug_central		biolink:Association
DrugCentral:4181	biolink:molecularly_interacts_with	UniProtKB:P56696	RO:0002436	drug_central		biolink:Association
DrugCentral:4181	biolink:molecularly_interacts_with	UniProtKB:Q9NR82	RO:0002436	drug_central		biolink:Association
DrugCentral:4181	biolink:molecularly_interacts_with	UniProtKB:O43525	RO:0002436	drug_central		biolink:Association
DrugCentral:4182	biolink:molecularly_interacts_with	UniProtKB:P00742	RO:0002436	drug_central	Inhibition of Factor 10a	biolink:Association
DrugCentral:4182	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y6	RO:0002436	drug_central		biolink:Association
DrugCentral:4183	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity to human beta2-adrenoceptor by radioligand binding assay	biolink:Association
DrugCentral:4183	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Displacement of [3H]CGP12177 from human beta-1 adrenoceptor	biolink:Association
DrugCentral:4183	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity to dopamine 2 receptor	biolink:Association
DrugCentral:4183	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:4184	biolink:molecularly_interacts_with	UniProtKB:Q9H244	RO:0002436	drug_central	Displacement of [33P]2-MeS-ADP from human recombinant P2Y12 receptor expressed in CHO cell membranes by scintillation counting method	biolink:Association
DrugCentral:4184	biolink:molecularly_interacts_with	UniProtKB:Q99808	RO:0002436	drug_central		biolink:Association
DrugCentral:4185	biolink:molecularly_interacts_with	UniProtKB:P04049	RO:0002436	drug_central	Inhibition of C-Raf in presence of 100 uM ATP	biolink:Association
DrugCentral:4185	biolink:molecularly_interacts_with	UniProtKB:P15056	RO:0002436	drug_central	Inhibition of wild type BRAF (unknown origin)	biolink:Association
DrugCentral:4185	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central		biolink:Association
DrugCentral:4186	biolink:molecularly_interacts_with	UniProtKB:P46663	RO:0002436	drug_central		biolink:Association
DrugCentral:4186	biolink:molecularly_interacts_with	UniProtKB:P30411	RO:0002436	drug_central	Binding affinity towards human cloned Bradykinin receptor B2 expressed in CHO cells by [3H]bradykinin displacement.	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(D835Y) kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q92772	RO:0002436	drug_central	Binding constant for CDKL2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(T315I)-phosphorylated kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(G719C) kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O15075	RO:0002436	drug_central	Binding constant for DCAMKL1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O15146	RO:0002436	drug_central	Binding constant for MUSK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central	Binding constant for FLT1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Binding constant for FGFR3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q8TDR2	RO:0002436	drug_central	Binding constant for STK35 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Binding constant for INSR kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q96SB4	RO:0002436	drug_central	Binding constant for SRPK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q92630	RO:0002436	drug_central	Binding constant for DYRK2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O14730	RO:0002436	drug_central	Binding constant for RIOK3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET(M1250T) kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P46734	RO:0002436	drug_central	Binding constant for MEK3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Binding constant for RIPK2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central	Binding constant for EPHB4 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q8IY84	RO:0002436	drug_central	Binding constant for NIM1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q52WX2	RO:0002436	drug_central	Binding constant for SBK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q6ZN16	RO:0002436	drug_central	Binding constant for MAP3K15 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Binding constant for AURKA kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Binding constant for JAK1(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q08881	RO:0002436	drug_central	Binding constant for ITK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P43405	RO:0002436	drug_central	Binding constant for SYK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P19525	RO:0002436	drug_central	Binding constant for PRKR kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central	Binding constant for BTK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P21127	RO:0002436	drug_central	Binding constant for CDC2L1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q15139	RO:0002436	drug_central	Binding constant for PRKD1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O43283	RO:0002436	drug_central	Binding constant for LZK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9UHD2	RO:0002436	drug_central	Binding constant for TBK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P21709	RO:0002436	drug_central	Binding constant for EPHA1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q8TDX7	RO:0002436	drug_central	Binding constant for NEK7 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for HPK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q96D53	RO:0002436	drug_central	Binding constant for ADCK4 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O94806	RO:0002436	drug_central	Binding constant for PRKD3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O43318	RO:0002436	drug_central	Binding constant for TAK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P29322	RO:0002436	drug_central	Binding constant for EPHA8 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P29317	RO:0002436	drug_central	Binding constant for EPHA2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Binding constant for EPHA3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P16591	RO:0002436	drug_central	Binding constant for FER kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Binding constant for PLK4 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q2M2I8	RO:0002436	drug_central	Binding constant for AAK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q7L7X3	RO:0002436	drug_central	Binding constant for TAOK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q59H18	RO:0002436	drug_central	Binding constant for TNNI3K kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Binding constant for AURKC kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central	Binding constant for TRKA kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q13464	RO:0002436	drug_central	Binding constant for ROCK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q8NFD2	RO:0002436	drug_central	Binding constant for ANKK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding constant for HIPK4 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q8N568	RO:0002436	drug_central	Binding constant for DCAMKL2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding constant for MINK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9NWZ3	RO:0002436	drug_central	Binding constant for IRAK4 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P14616	RO:0002436	drug_central	Binding constant for INSRR kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(V559D,T670I) kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P08069	RO:0002436	drug_central	Binding constant for IGF1R kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Binding constant for EPHA6 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q96RR4	RO:0002436	drug_central	Binding constant for CAMKK2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q96GD4	RO:0002436	drug_central	Binding constant for AURKB kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O00238	RO:0002436	drug_central	Binding constant for BMPR1B kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q04912	RO:0002436	drug_central	Binding constant for MST1R kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Binding constant for TYK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q13043	RO:0002436	drug_central	Binding constant for MST1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q15375	RO:0002436	drug_central	Binding constant for EPHA7 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q13188	RO:0002436	drug_central	Binding constant for MST2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O14920	RO:0002436	drug_central	Binding constant for IKK-beta kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q8TD19	RO:0002436	drug_central	Binding constant for NEK9 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9UL54	RO:0002436	drug_central	Binding constant for TAOK2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q13131	RO:0002436	drug_central	Binding constant for AMPK-alpha1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P51813	RO:0002436	drug_central	Binding constant for BMX kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P54756	RO:0002436	drug_central	Binding constant for EPHA5 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P53667	RO:0002436	drug_central	Binding constant for LIMK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P06748	RO:0002436	drug_central	Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporation assay	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporation assay	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q8IYT8	RO:0002436	drug_central	Binding constant for ULK2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P54764	RO:0002436	drug_central	Binding constant for EPHA4 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central	Binding constant for EPHB1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central	Binding constant for TNK2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q15569	RO:0002436	drug_central	Binding constant for TESK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q05397	RO:0002436	drug_central	Binding constant for FAK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central	Binding constant for TRKC kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P43403	RO:0002436	drug_central	Binding constant for ZAP70 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q04771	RO:0002436	drug_central	Binding constant for ACVR1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9Y616	RO:0002436	drug_central	Binding constant for IRAK3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P32298	RO:0002436	drug_central	Binding constant for GRK4 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding constant for MAP3K2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding constant for ULK3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9P289	RO:0002436	drug_central	Binding constant for MST4 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q14289	RO:0002436	drug_central	Binding constant for PYK2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding constant for TIE2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q14164	RO:0002436	drug_central	Binding constant for IKK-epsilon kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O14936	RO:0002436	drug_central	Binding constant for CASK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q6XUX3	RO:0002436	drug_central	Binding constant for RIPK5 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P08922	RO:0002436	drug_central	Binding constant for ROS1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for SIK2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9H2K8	RO:0002436	drug_central	Binding constant for TAOK3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q13233	RO:0002436	drug_central	Binding constant for MAP3K1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P50613	RO:0002436	drug_central	Binding constant for CDK7 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central	Binding constant for ROCK2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P0C264	RO:0002436	drug_central	Binding constant for SgK110 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P36896	RO:0002436	drug_central	Binding constant for ACVR1B kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P36897	RO:0002436	drug_central	Binding constant for TGFBR1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(M918T) kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q09013	RO:0002436	drug_central	Binding constant for DMPK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q06418	RO:0002436	drug_central	Binding constant for TYRO3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P07332	RO:0002436	drug_central	Binding constant for FES kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central	Binding constant for LTK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central	Binding constant for TRKB kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9UPE1	RO:0002436	drug_central	Binding constant for SRPK3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P53671	RO:0002436	drug_central	Binding constant for LIMK2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Inhibition of wild type human recombinant ALK kinase domain (amino acids 1093 to 1141) expressed in baculovirus system using 5'FAM-KKSRGDYMTMQIG-CONH2 as substrate incubated for 15 mins prior to ATP addition measured after 1 hr by microfluidic mobility shift assay	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q12852	RO:0002436	drug_central	Binding constant for DLK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q13546	RO:0002436	drug_central	Binding constant for RIPK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q99755	RO:0002436	drug_central	Binding constant for PIP5K1A kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding constant for MAP3K3 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9UQ88	RO:0002436	drug_central	Binding constant for CDC2L2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q9BRS2	RO:0002436	drug_central	Binding constant for RIOK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P23443	RO:0002436	drug_central	Binding constant for S6K1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:O75385	RO:0002436	drug_central	Binding constant for ULK1 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:P57078	RO:0002436	drug_central	Binding constant for RIPK4 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q13164	RO:0002436	drug_central	Binding constant for ERK5 kinase domain	biolink:Association
DrugCentral:4187	biolink:molecularly_interacts_with	UniProtKB:Q13470	RO:0002436	drug_central	Binding constant for TNK1 kinase domain	biolink:Association
DrugCentral:4189	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central	human recombinant PR-B isoform in Sf9 cells	biolink:Association
DrugCentral:4189	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:4189	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:4189	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:4189	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:4189	biolink:molecularly_interacts_with	UniProtKB:P04278	RO:0002436	drug_central	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	biolink:Association
DrugCentral:4189	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central	Binding constant for MEK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(H396P)-non phosphorylated kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UBF8	RO:0002436	drug_central	Binding constant for PIK4CB kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O15075	RO:0002436	drug_central	Binding constant for DCAMKL1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q14012	RO:0002436	drug_central	Binding constant for CAMK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q96SB4	RO:0002436	drug_central	Binding constant for SRPK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q92630	RO:0002436	drug_central	Binding constant for DYRK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O14730	RO:0002436	drug_central	Binding constant for RIOK3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P51956	RO:0002436	drug_central	Binding constant for NEK3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P46734	RO:0002436	drug_central	Binding constant for MEK3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q13554	RO:0002436	drug_central	Binding constant for CAMK2B kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UK32	RO:0002436	drug_central	Binding constant for RSK4(Kin.Dom.2-C-terminal) kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q15418	RO:0002436	drug_central	Binding constant for RSK1(Kin.Dom.2-C-terminal) kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q52WX2	RO:0002436	drug_central	Binding constant for SBK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q6ZN16	RO:0002436	drug_central	Binding constant for MAP3K15 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9Y2H9	RO:0002436	drug_central	Binding constant for MAST1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Inhibition of JAK2/TYK2 in human whole blood assessed as inhibition of IL-23-induced STAT-3 phosphorylation preincubated for 45 mins followed by IL-23 addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Inhibition of JAK2/TYK2 in human whole blood assessed as inhibition of IL-23-induced STAT-3 phosphorylation preincubated for 45 mins followed by IL-23 addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Inhibition of JAK1/JAK2/TYK2 in human whole blood assessed as inhibition of IL-6-induced STAT-1 phosphorylation preincubated for 45 mins followed by IL-6 addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Inhibition of JAK1/JAK2/TYK2 in human whole blood assessed as inhibition of IL-6-induced STAT-1 phosphorylation preincubated for 45 mins followed by IL-6 addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Inhibition of JAK1/JAK2/TYK2 in human whole blood assessed as inhibition of IL-6-induced STAT-1 phosphorylation preincubated for 45 mins followed by IL-6 addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Inhibition of JAK1/TYK2 in human whole blood assessed as inhibition of IFN-alpha-induced STAT-3 phosphorylation preincubated for 45 mins followed by IFN-alpha addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Inhibition of JAK1/TYK2 in human whole blood assessed as inhibition of IFN-alpha-induced STAT-3 phosphorylation preincubated for 45 mins followed by IFN-alpha addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Inhibition of purified JAK1 incubated for 30 mins	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9H422	RO:0002436	drug_central	Binding constant for HIPK3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9H2X6	RO:0002436	drug_central	Binding constant for HIPK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q14680	RO:0002436	drug_central	Binding constant for MELK kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P53350	RO:0002436	drug_central	Binding constant for PLK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UHD2	RO:0002436	drug_central	Binding constant for TBK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q8TDX7	RO:0002436	drug_central	Binding constant for NEK7 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O75460	RO:0002436	drug_central	Binding constant for ERN1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P15056	RO:0002436	drug_central	Binding constant for BRAF kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O95747	RO:0002436	drug_central	Binding constant for OSR1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UEW8	RO:0002436	drug_central	Binding constant for STK39 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O43318	RO:0002436	drug_central	Binding constant for TAK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P49760	RO:0002436	drug_central	Binding constant for CLK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q8WTQ7	RO:0002436	drug_central	Binding constant for GRK7 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q86Z02	RO:0002436	drug_central	Binding constant for HIPK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Inhibition of JAK3/1 in human T cells expressing CD3 assessed as inhibition of IL2-stimulated STAT5a phosphorylation	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Inhibition of JAK3/1 in human T cells expressing CD3 assessed as inhibition of IL2-stimulated STAT5a phosphorylation	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P33981	RO:0002436	drug_central	Binding constant for TTK kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Inhibition of JAK2/1 in human T cells expressing CD3 assessed as inhibition of IFNgamma-stimulated STAT1 phosphorylation	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Inhibition of JAK2/1 in human T cells expressing CD3 assessed as inhibition of IFNgamma-stimulated STAT1 phosphorylation	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Binding constant for EPHA3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O75716	RO:0002436	drug_central	Binding constant for STK16 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O94768	RO:0002436	drug_central	Binding constant for DRAK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q13555	RO:0002436	drug_central	Binding constant for CAMK2G kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Binding constant for PLK4 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q2M2I8	RO:0002436	drug_central	Binding constant for AAK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q7KZI7	RO:0002436	drug_central	Binding constant for MARK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q02156	RO:0002436	drug_central	Binding constant for PRKCE kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O75582	RO:0002436	drug_central	Binding constant for RPS6KA5(Kin.Dom.2-C-terminal) kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P19784	RO:0002436	drug_central	Binding constant for CSNK2A2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q7L7X3	RO:0002436	drug_central	Binding constant for TAOK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Binding constant for AURKC kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P15735	RO:0002436	drug_central	Binding constant for PHKG2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central	Binding constant for TRKA kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q13464	RO:0002436	drug_central	Binding constant for ROCK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q8NFD2	RO:0002436	drug_central	Binding constant for ANKK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O00506	RO:0002436	drug_central	Binding constant for YSK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q15746	RO:0002436	drug_central	Binding constant for MYLK kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q8N568	RO:0002436	drug_central	Binding constant for DCAMKL2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q5S007	RO:0002436	drug_central	Binding constant for LRRK2(G2019S) kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9NQU5	RO:0002436	drug_central	Binding constant for PAK6 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(A829P) kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9P286	RO:0002436	drug_central	Binding constant for PAK7 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UEE5	RO:0002436	drug_central	Binding constant for DRAK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O75676	RO:0002436	drug_central	Binding constant for RPS6KA4(Kin.Dom.2-C-terminal) kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9HAZ1	RO:0002436	drug_central	Binding constant for CLK4 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9HBH9	RO:0002436	drug_central	Binding constant for MKNK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UIK4	RO:0002436	drug_central	Binding constant for DAPK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O00238	RO:0002436	drug_central	Binding constant for BMPR1B kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Inhibition of TYK2 kinase domain using N-terminal 5-carboxyfluorescein-tagged Val-Ala-Leu-Val-Asp-Gly-Tyr-Phe-Arg-Leu-Thr-Thr as substrate after 30 mins	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q8IU85	RO:0002436	drug_central	Binding constant for CAMK1D kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q96NX5	RO:0002436	drug_central	Binding constant for CAMK1G kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O14920	RO:0002436	drug_central	Binding constant for IKK-beta kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UL54	RO:0002436	drug_central	Binding constant for TAOK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q15349	RO:0002436	drug_central	Binding constant for RSK3(Kin.Dom.2-C-terminal) kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q8IYT8	RO:0002436	drug_central	Binding constant for ULK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q16816	RO:0002436	drug_central	Binding constant for PHKG1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central	Binding constant for TNK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P68400	RO:0002436	drug_central	Binding constant for CSNK2A1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central	Binding constant for TRKC kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q15835	RO:0002436	drug_central	Binding constant for GRK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UQM7	RO:0002436	drug_central	Binding constant for CAMK2A kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P32298	RO:0002436	drug_central	Binding constant for GRK4 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding constant for MAP3K2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding constant for ULK3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9P289	RO:0002436	drug_central	Binding constant for MST4 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9NYY3	RO:0002436	drug_central	Binding constant for PLK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q13873	RO:0002436	drug_central	Binding constant for BMPR2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q14164	RO:0002436	drug_central	Binding constant for IKK-epsilon kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O14936	RO:0002436	drug_central	Binding constant for CASK kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P45983	RO:0002436	drug_central	Binding constant for JNK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9H2K8	RO:0002436	drug_central	Binding constant for TAOK3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P48729	RO:0002436	drug_central	Binding constant for CSNK1A1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q13233	RO:0002436	drug_central	Binding constant for MAP3K1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P50613	RO:0002436	drug_central	Binding constant for CDK7 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9Y2K2	RO:0002436	drug_central	Binding constant for QSK kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central	Binding constant for ROCK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P53355	RO:0002436	drug_central	Binding constant for DAPK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P0C264	RO:0002436	drug_central	Binding constant for SgK110 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O43293	RO:0002436	drug_central	Binding constant for DAPK3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O96013	RO:0002436	drug_central	Binding constant for PAK4 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9C098	RO:0002436	drug_central	Binding constant for DCAMKL3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q13627	RO:0002436	drug_central	Binding constant for DYRK1A kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(V804M) kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q09013	RO:0002436	drug_central	Binding constant for DMPK kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central	Binding constant for LTK kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9H4B4	RO:0002436	drug_central	Binding constant for PLK3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central	Binding constant for TRKB kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central	Binding constant for MEK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P45985	RO:0002436	drug_central	Binding constant for MEK4 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UPE1	RO:0002436	drug_central	Binding constant for SRPK3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q86Y07	RO:0002436	drug_central	Binding constant for VRK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Binding constant for ALK kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding constant for MAP3K3 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9BRS2	RO:0002436	drug_central	Binding constant for RIOK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q9BVS4	RO:0002436	drug_central	Binding constant for RIOK2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:O75385	RO:0002436	drug_central	Binding constant for ULK1 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q13557	RO:0002436	drug_central	Binding constant for CAMK2D kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q13237	RO:0002436	drug_central	Binding constant for PRKG2 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:P57078	RO:0002436	drug_central	Binding constant for RIPK4 kinase domain	biolink:Association
DrugCentral:4190	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:4191	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:4191	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:4191	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:4191	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:4191	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:4192	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4192	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:4192	biolink:molecularly_interacts_with	UniProtKB:Q4U2R8	RO:0002436	drug_central		biolink:Association
DrugCentral:4192	biolink:molecularly_interacts_with	UniProtKB:Q8TCC7	RO:0002436	drug_central		biolink:Association
DrugCentral:4196	biolink:molecularly_interacts_with	UniProtKB:Q9BXJ7	RO:0002436	drug_central		biolink:Association
DrugCentral:4196	biolink:molecularly_interacts_with	UniProtKB:Q96EY8	RO:0002436	drug_central		biolink:Association
DrugCentral:4196	biolink:molecularly_interacts_with	UniProtKB:Q8IVH4	RO:0002436	drug_central		biolink:Association
DrugCentral:4196	biolink:molecularly_interacts_with	UniProtKB:P20062	RO:0002436	drug_central		biolink:Association
DrugCentral:4196	biolink:molecularly_interacts_with	UniProtKB:P20061	RO:0002436	drug_central		biolink:Association
DrugCentral:4196	biolink:molecularly_interacts_with	UniProtKB:Q9UBK8	RO:0002436	drug_central		biolink:Association
DrugCentral:4196	biolink:molecularly_interacts_with	UniProtKB:Q99707	RO:0002436	drug_central		biolink:Association
DrugCentral:4197	biolink:molecularly_interacts_with	UniProtKB:P02753	RO:0002436	drug_central		biolink:Association
DrugCentral:4199	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 by Lineweaver-Burk curves	biolink:Association
DrugCentral:4203	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human cytosolic carbonic anhydrase 1 by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:4207	biolink:molecularly_interacts_with	UniProtKB:P29218	RO:0002436	drug_central	Mechanism of Action; CHEMBL1786; SINGLE PROTEIN	biolink:Association
DrugCentral:4207	biolink:molecularly_interacts_with	UniProtKB:P49840	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095188; PROTEIN FAMILY	biolink:Association
DrugCentral:4207	biolink:molecularly_interacts_with	UniProtKB:P49841	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095188; PROTEIN FAMILY	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P14780	RO:0002436	drug_central	DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P03956	RO:0002436	drug_central	DRUGMATRIX: Peptidase, Matrix Metalloproteinase-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2)	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:O15244	RO:0002436	drug_central	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptor	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central	Displacement of [3H]-YM-09151-2 (0.06 nM) from human Dopamine receptor D4 expressed in CHO cells	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1D adrenergic receptor	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central	Binding affinity was determined for the alpha-1D adrenergic receptor	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptor	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibitory concentration against potassium channel HERG	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptor	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptor	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:Q86VL8	RO:0002436	drug_central	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:Q96FL8	RO:0002436	drug_central	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:4209	biolink:molecularly_interacts_with	UniProtKB:P16083	RO:0002436	drug_central	Binding affinity to low affinity melatonin (MT3) site of quinone reductase 2	biolink:Association
DrugCentral:4211	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Dissociation constant for binding to SH2 domain of Fyn protein kinase	biolink:Association
DrugCentral:4211	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinase	biolink:Association
DrugCentral:4213	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:4213	biolink:molecularly_interacts_with	UniProtKB:P08185	RO:0002436	drug_central		biolink:Association
DrugCentral:4218	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095158; PROTEIN FAMILY	biolink:Association
DrugCentral:4218	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095158; PROTEIN FAMILY	biolink:Association
DrugCentral:4218	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095158; PROTEIN FAMILY	biolink:Association
DrugCentral:4219	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV	biolink:Association
DrugCentral:4221	biolink:molecularly_interacts_with	UniProtKB:P14679	RO:0002436	drug_central	Mechanism of Action; CHEMBL1973; SINGLE PROTEIN	biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Binding of vilazodone to human 5-HT<sub>1A</sub> receptors against [<sup></sup>3H]8-OH-DPAT (DPAT)	biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:Q13639	RO:0002436	drug_central		biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Inhibition of alpha-2-adrenergic receptor	biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Inhibition of alpha-2-adrenergic receptor	biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Inhibition of alpha-2-adrenergic receptor	biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	Inhibition of alpha-1-adrenergic receptor	biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central	Inhibition of alpha-1-adrenergic receptor	biolink:Association
DrugCentral:4223	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central	Inhibition of alpha-1-adrenergic receptor	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Binding constant for JNK3 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central	Binding constant for MEK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(T315I)-phosphorylated kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(K663Q) kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q92772	RO:0002436	drug_central	Binding constant for CDKL2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(G719C) kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central	Binding constant for FLT1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Binding constant for VEGFR2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Binding constant for FGFR3 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q96SB4	RO:0002436	drug_central	Binding constant for SRPK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Binding constant for PDGFRA kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O14730	RO:0002436	drug_central	Binding constant for RIOK3 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Binding constant for RIPK2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Binding constant for AURKA kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q08881	RO:0002436	drug_central	Binding constant for ITK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9NYL2	RO:0002436	drug_central	Binding constant for ZAK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P19525	RO:0002436	drug_central	Binding constant for PRKR kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for HPK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P33981	RO:0002436	drug_central	Binding constant for TTK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O75716	RO:0002436	drug_central	Binding constant for STK16 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Inhibition of human PLK4	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q2M2I8	RO:0002436	drug_central	Binding constant for AAK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P19784	RO:0002436	drug_central	Binding constant for CSNK2A2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q16513	RO:0002436	drug_central	Binding constant for PKN2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central	Binding constant for CSK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Binding constant for AURKC kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central	Binding constant for TRKA kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	Binding constant for FGFR1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Binding constant for FGFR2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q8NEV4	RO:0002436	drug_central	Binding constant for MYO3A kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q8NFD2	RO:0002436	drug_central	Binding constant for ANKK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9Y6R4	RO:0002436	drug_central	Binding constant for MAP3K4 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding constant for MINK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q5S007	RO:0002436	drug_central	Binding constant for LRRK2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(V559D) kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q96RR4	RO:0002436	drug_central	Binding constant for CAMKK2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q96GD4	RO:0002436	drug_central	Binding constant for AURKB kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O00238	RO:0002436	drug_central	Binding constant for BMPR1B kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Binding constant for TYK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q13043	RO:0002436	drug_central	Binding constant for MST1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q8N5S9	RO:0002436	drug_central	Binding constant for CAMKK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q13188	RO:0002436	drug_central	Binding constant for MST2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q8IYT8	RO:0002436	drug_central	Binding constant for ULK2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central	Binding constant for TNK2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q00536	RO:0002436	drug_central	Binding constant for PCTK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q15569	RO:0002436	drug_central	Binding constant for TESK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9Y5S2	RO:0002436	drug_central	Binding constant for MRCKB kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P32298	RO:0002436	drug_central	Binding constant for GRK4 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding constant for ULK3 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q13705	RO:0002436	drug_central	Binding constant for ACVR2B kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding constant for TIE2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P08922	RO:0002436	drug_central	Binding constant for ROS1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P45983	RO:0002436	drug_central	Binding constant for JNK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P35916	RO:0002436	drug_central	Binding constant for FLT4 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P57058	RO:0002436	drug_central	Binding constant for HUNK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central	Binding constant for DDR2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O96013	RO:0002436	drug_central	Binding constant for PAK4 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(M918T) kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:O95819	RO:0002436	drug_central	Binding constant for MAP4K4 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9H1R3	RO:0002436	drug_central	Binding constant for MYLK2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P80192	RO:0002436	drug_central	Binding constant for MLK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central	Binding constant for MEK2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9UPE1	RO:0002436	drug_central	Binding constant for SRPK3 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q12852	RO:0002436	drug_central	Binding constant for DLK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q32MK0	RO:0002436	drug_central	Binding constant for MLCK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q13546	RO:0002436	drug_central	Binding constant for RIPK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding constant for MAP3K3 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q9BRS2	RO:0002436	drug_central	Binding constant for RIOK1 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P57078	RO:0002436	drug_central	Binding constant for RIPK4 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:P57059	RO:0002436	drug_central	Binding constant for SIK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:4225	biolink:molecularly_interacts_with	UniProtKB:Q13470	RO:0002436	drug_central	Binding constant for TNK1 kinase domain	biolink:Association
DrugCentral:4226	biolink:molecularly_interacts_with	UniProtKB:Q05655	RO:0002436	drug_central	Colo-205 cells	biolink:Association
DrugCentral:4226	biolink:molecularly_interacts_with	UniProtKB:P17252	RO:0002436	drug_central	Colo-205 cells	biolink:Association
DrugCentral:4226	biolink:molecularly_interacts_with	UniProtKB:Q02156	RO:0002436	drug_central	Colo-205 cells	biolink:Association
DrugCentral:4226	biolink:molecularly_interacts_with	UniProtKB:Q15139	RO:0002436	drug_central	Colo-205 cells	biolink:Association
DrugCentral:4226	biolink:molecularly_interacts_with	UniProtKB:P05129	RO:0002436	drug_central		biolink:Association
DrugCentral:4227	biolink:molecularly_interacts_with	UniProtKB:Q15465	RO:0002436	drug_central	Inhibition of human SHH pathway in mouse S12 cells assessed as GLI-mediated transcriptional activity after 48 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:4227	biolink:molecularly_interacts_with	UniProtKB:Q99835	RO:0002436	drug_central	Displacement of [3H]cyclopamine from wild type Smo expressed in U2OS cells after 2 hrs by scintillation counting	biolink:Association
DrugCentral:4228	biolink:molecularly_interacts_with	UniProtKB:P13569	RO:0002436	drug_central	Potentiation of human CFTR F508del mutant expressed in mouse NIH-3T3 cells after 30 mins by fluorescent voltage sensing optical assay	biolink:Association
DrugCentral:4229	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central	Mechanism of Action; CHEMBL1987; SINGLE PROTEIN	biolink:Association
DrugCentral:4234	biolink:molecularly_interacts_with	UniProtKB:P19235	RO:0002436	drug_central		biolink:Association
DrugCentral:4242	biolink:molecularly_interacts_with	UniProtKB:P14679	RO:0002436	drug_central	Mechanism of Action; CHEMBL1973; SINGLE PROTEIN	biolink:Association
DrugCentral:4247	biolink:molecularly_interacts_with	UniProtKB:Q8NER1	RO:0002436	drug_central	Inhibition of TRPV1-mediated membrane currents in human DRG neurons	biolink:Association
DrugCentral:4247	biolink:molecularly_interacts_with	UniProtKB:O00255	RO:0002436	drug_central	Binding affinity to menin (unknown origin) by isothermal titration calorimetry analysis	biolink:Association
DrugCentral:4247	biolink:molecularly_interacts_with	UniProtKB:O95237	RO:0002436	drug_central	Compound tested in vitro for inhibition of translation using highly active Escherichia coli S30 and a plasmid containing a gene expressing truncated lecithin retinol acyltransferase	biolink:Association
DrugCentral:4248	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4248	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4248	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 13 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4248	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4248	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 5A preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4248	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4248	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4248	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4248	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 5B preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4248	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 6 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4257	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094253; PROTEIN FAMILY	biolink:Association
DrugCentral:4257	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094253; PROTEIN FAMILY	biolink:Association
DrugCentral:4258	biolink:molecularly_interacts_with	UniProtKB:O75762	RO:0002436	drug_central	Activation of human TRPA1 assessed as stimulation of intracellular Ca2+ levels	biolink:Association
DrugCentral:4260	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central		biolink:Association
DrugCentral:4260	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central		biolink:Association
DrugCentral:4265	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central	Inhibition of human DHFR after 2 mins	biolink:Association
DrugCentral:4266	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human CA2 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:4266	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human CA12 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:4266	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human CA4 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:4266	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human CA3 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:4266	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human CA14 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:4266	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human CA9 by stopped-flow CO2 hydration assay	biolink:Association
DrugCentral:4266	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human recombinant alpha-carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay	biolink:Association
DrugCentral:4267	biolink:molecularly_interacts_with	UniProtKB:P14679	RO:0002436	drug_central	Inhibition of tyrosinase in Melan-a cells	biolink:Association
DrugCentral:4283	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:4283	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:4289	biolink:molecularly_interacts_with	UniProtKB:O14842	RO:0002436	drug_central		biolink:Association
DrugCentral:4289	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of aromatase in human placental microsomes by radiometric method	biolink:Association
DrugCentral:4289	biolink:molecularly_interacts_with	UniProtKB:Q8TDS5	RO:0002436	drug_central	Antagonist activity at human OXE receptor fused with G-alphai assessed as inhibition of 5-oxo-ETE-induced GTPgammaS binding after 60 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:4296	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 4 by Lineweaver-Burk curves	biolink:Association
DrugCentral:4298	biolink:molecularly_interacts_with	UniProtKB:P00734	RO:0002436	drug_central	Inhibition of human thrombin	biolink:Association
DrugCentral:4298	biolink:molecularly_interacts_with	UniProtKB:P00742	RO:0002436	drug_central	Inhibition of human factor 10a	biolink:Association
DrugCentral:4299	biolink:molecularly_interacts_with	UniProtKB:P08684	RO:0002436	drug_central	Inactivation of Human Hepatic Microsomal CYP3A-Dependent Midazolam 1'-Hydroxylase Activity	biolink:Association
DrugCentral:4299	biolink:molecularly_interacts_with	UniProtKB:P20815	RO:0002436	drug_central	Inactivation of Human Hepatic Microsomal CYP3A-Dependent Midazolam 1'-Hydroxylase Activity	biolink:Association
DrugCentral:4299	biolink:molecularly_interacts_with	UniProtKB:P24462	RO:0002436	drug_central	Inactivation of Human Hepatic Microsomal CYP3A-Dependent Midazolam 1'-Hydroxylase Activity	biolink:Association
DrugCentral:4299	biolink:molecularly_interacts_with	UniProtKB:Q9HB55	RO:0002436	drug_central	Inactivation of Human Hepatic Microsomal CYP3A-Dependent Midazolam 1'-Hydroxylase Activity	biolink:Association
DrugCentral:4302	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:4302	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:4302	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:4302	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:4302	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:4303	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:4303	biolink:molecularly_interacts_with	UniProtKB:P35499	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:4303	biolink:molecularly_interacts_with	UniProtKB:Q01118	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:4303	biolink:molecularly_interacts_with	UniProtKB:Q14524	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:4303	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:4303	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:4303	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:4303	biolink:molecularly_interacts_with	UniProtKB:Q9UI33	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:4303	biolink:molecularly_interacts_with	UniProtKB:Q9UQD0	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:4303	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y9	RO:0002436	drug_central	Mechanism of Action; CHEMBL2331043; PROTEIN FAMILY	biolink:Association
DrugCentral:4304	biolink:molecularly_interacts_with	UniProtKB:P31639	RO:0002436	drug_central		biolink:Association
DrugCentral:4304	biolink:molecularly_interacts_with	UniProtKB:Q9NY91	RO:0002436	drug_central	Inhibition of human SGLT2 expressed in CHO cells using methyl-alpha-D-glucopyranoside by liquid scintillation counting	biolink:Association
DrugCentral:4304	biolink:molecularly_interacts_with	UniProtKB:P13866	RO:0002436	drug_central	Inhibition of human SGLT2 expressed in african green monkey COS7 cells assessed as inhibition of [14C]-methyl-alpha-D-glucopyranoside uptake after 2 hrs by scintillation counting in presence of 25 % human plasma	biolink:Association
DrugCentral:4304	biolink:molecularly_interacts_with	UniProtKB:Q8WWX8	RO:0002436	drug_central	Inhibition of SGLT6 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation counting	biolink:Association
DrugCentral:4305	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central		biolink:Association
DrugCentral:4305	biolink:molecularly_interacts_with	UniProtKB:P51160	RO:0002436	drug_central		biolink:Association
DrugCentral:4308	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Binding affinity for human estrogen receptor alpha	biolink:Association
DrugCentral:4308	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Binding affinity for human estrogen receptor beta	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:Q16555	RO:0002436	drug_central		biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human recombinant CA2 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Binding affinity to human inactivated voltage-gated Na channel 1.7 expressed in HEK293 cells by patch-clamp technique	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant CA12 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human recombinant CA4 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant CA13 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human recombinant CA3 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant CA5A by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant CA14 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant CA7 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human recombinant CA9 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human recombinant CA1 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant CA5B by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4310	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human recombinant CA6 by stopped flow CO2 hydrase assay	biolink:Association
DrugCentral:4314	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:4314	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:4314	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:4314	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:4314	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Binding constant for JNK3 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(F317L)-phosphorylated kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(D835Y) kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(G719C) kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P45984	RO:0002436	drug_central	Binding constant for JNK2 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q92630	RO:0002436	drug_central	Binding constant for DYRK2 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P49674	RO:0002436	drug_central	Binding constant for CSNK1E kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Binding constant for RIPK2 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q9UK32	RO:0002436	drug_central	Binding constant for RSK4(Kin.Dom.2-C-terminal) kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q52WX2	RO:0002436	drug_central	Binding constant for SBK1 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q9BUB5	RO:0002436	drug_central	Binding constant for MKNK1 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	Binding constant for ERBB2 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P15735	RO:0002436	drug_central	Binding constant for PHKG2 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:O14578	RO:0002436	drug_central	Binding constant for CIT kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding constant for HIPK4 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central	Binding constant for ERBB4 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q9UEE5	RO:0002436	drug_central	Binding constant for DRAK1 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Binding constant for EPHA6 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q9HBH9	RO:0002436	drug_central	Binding constant for MKNK2 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q16816	RO:0002436	drug_central	Binding constant for PHKG1 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q9Y463	RO:0002436	drug_central	Binding constant for DYRK1B kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P21860	RO:0002436	drug_central	Binding constant for ERBB3 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q13627	RO:0002436	drug_central	Binding constant for DYRK1A kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:4318	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	Binding constant for p38-alpha kinase domain	biolink:Association
DrugCentral:4322	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central		biolink:Association
DrugCentral:4326	biolink:molecularly_interacts_with	UniProtKB:Q13258	RO:0002436	drug_central	Binding affinity to human DP receptor expressed in HEK293 cells	biolink:Association
DrugCentral:4326	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central	Binding affinity to human FP receptor expressed in HEK293 cells	biolink:Association
DrugCentral:4326	biolink:molecularly_interacts_with	UniProtKB:P43119	RO:0002436	drug_central	Binding affinity to human IP receptor expressed in HEK293 cells	biolink:Association
DrugCentral:4326	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central	Binding affinity to human EP2 receptor expressed in HEK293 cells	biolink:Association
DrugCentral:4326	biolink:molecularly_interacts_with	UniProtKB:P43115	RO:0002436	drug_central	Binding affinity to human EP3 receptor expressed in HEK293 cells	biolink:Association
DrugCentral:4326	biolink:molecularly_interacts_with	UniProtKB:Q9Y5Y4	RO:0002436	drug_central	Activity at CRTH2 receptor	biolink:Association
DrugCentral:4326	biolink:molecularly_interacts_with	UniProtKB:P21731	RO:0002436	drug_central	Binding affinity to human TP receptor expressed in HEK293 cells	biolink:Association
DrugCentral:4326	biolink:molecularly_interacts_with	UniProtKB:P34995	RO:0002436	drug_central	Binding affinity to human EP1 receptor expressed in HEK293 cells	biolink:Association
DrugCentral:4329	biolink:molecularly_interacts_with	UniProtKB:P32745	RO:0002436	drug_central		biolink:Association
DrugCentral:4329	biolink:molecularly_interacts_with	UniProtKB:P30872	RO:0002436	drug_central		biolink:Association
DrugCentral:4329	biolink:molecularly_interacts_with	UniProtKB:P35346	RO:0002436	drug_central		biolink:Association
DrugCentral:4329	biolink:molecularly_interacts_with	UniProtKB:P30874	RO:0002436	drug_central		biolink:Association
DrugCentral:4334	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Inhibition of binding to recombinant human ERalpha by scintillation proximity assay	biolink:Association
DrugCentral:4334	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Inhibition of binding to recombinant human ERbeta by scintillation proximity assay	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:O43525	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:O43526	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:O95259	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:P16389	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:P17658	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:P22001	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:P22459	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:P48547	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:P51787	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:P56696	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q03721	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q09470	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q14003	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q14721	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q16322	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q6PIU1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q8NCM2	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q8TAE7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q8TDN1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q8TDN2	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q92953	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q96KK3	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q96L42	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q96PR1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q96RP8	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9BQ31	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9H252	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9H3M0	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9NR82	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9NS40	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9NSA2	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9NZV8	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9UIX4	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9UJ96	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9UK17	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9ULD8	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9ULS6	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4336	biolink:molecularly_interacts_with	UniProtKB:Q9UQ05	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4337	biolink:molecularly_interacts_with	UniProtKB:P24530	RO:0002436	drug_central		biolink:Association
DrugCentral:4337	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central		biolink:Association
DrugCentral:4340	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central	Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence assay	biolink:Association
DrugCentral:4342	biolink:molecularly_interacts_with	UniProtKB:Q8NER1	RO:0002436	drug_central	increases in intracellular (HEK-293 cells) Ca2+ using Fluo-3 dye	biolink:Association
DrugCentral:4344	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:4344	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA))	biolink:Association
DrugCentral:4344	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4344	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4344	biolink:molecularly_interacts_with	UniProtKB:Q08209	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Phosphatase, PPP3CA (Calcineurin, PP2B) enzyme inhibition (substrate: DiFMUP)	biolink:Association
DrugCentral:4344	biolink:molecularly_interacts_with	UniProtKB:O43194	RO:0002436	drug_central		biolink:Association
DrugCentral:4349	biolink:molecularly_interacts_with	UniProtKB:Q16881	RO:0002436	drug_central		biolink:Association
DrugCentral:4349	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central		biolink:Association
DrugCentral:4353	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	inhibition of [3H]-pyrilamine binding to human recombinant histamine H1-receptors	biolink:Association
DrugCentral:4358	biolink:molecularly_interacts_with	UniProtKB:P35228	RO:0002436	drug_central	Binding affinity to truncated iNOS construct (1-490) by spectral assay	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central	Binding constant for MEK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(D835H) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(F317L)-phosphorylated kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(E746-A750del) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q04759	RO:0002436	drug_central	Binding constant for PRKCQ kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8TDR2	RO:0002436	drug_central	Binding constant for STK35 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Binding constant for PDGFRA kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O14730	RO:0002436	drug_central	Binding constant for RIOK3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P49674	RO:0002436	drug_central	Binding constant for CSNK1E kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8WXR4	RO:0002436	drug_central	Binding constant for MYO3B kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P46734	RO:0002436	drug_central	Binding constant for MEK3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O75914	RO:0002436	drug_central	Binding constant for PAK3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q96Q40	RO:0002436	drug_central	Binding constant for PFTAIRE2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O43353	RO:0002436	drug_central	Binding constant for RIPK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central	Binding constant for EPHB4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UK32	RO:0002436	drug_central	Binding constant for RSK4(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8IY84	RO:0002436	drug_central	Binding constant for NIM1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9Y2H9	RO:0002436	drug_central	Binding constant for MAST1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P48730	RO:0002436	drug_central	Binding constant for CSNK1D kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q08881	RO:0002436	drug_central	Binding constant for ITK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9NYL2	RO:0002436	drug_central	Binding constant for ZAK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9H422	RO:0002436	drug_central	Binding constant for HIPK3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9H2X6	RO:0002436	drug_central	Binding constant for HIPK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P43405	RO:0002436	drug_central	Binding constant for SYK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P53350	RO:0002436	drug_central	Binding constant for PLK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P30291	RO:0002436	drug_central	Binding constant for WEE1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central	Binding constant for BTK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O60285	RO:0002436	drug_central	Binding constant for ARK5 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O43283	RO:0002436	drug_central	Binding constant for LZK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UHD2	RO:0002436	drug_central	Binding constant for TBK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P21709	RO:0002436	drug_central	Binding constant for EPHA1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for HPK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8NG66	RO:0002436	drug_central	Binding constant for NEK11 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O94806	RO:0002436	drug_central	Binding constant for PRKD3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UEW8	RO:0002436	drug_central	Binding constant for STK39 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O43318	RO:0002436	drug_central	Binding constant for TAK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P49760	RO:0002436	drug_central	Binding constant for CLK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P49761	RO:0002436	drug_central	Binding constant for CLK3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8WTQ7	RO:0002436	drug_central	Binding constant for GRK7 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q86Z02	RO:0002436	drug_central	Binding constant for HIPK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P49759	RO:0002436	drug_central	Binding constant for CLK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P29322	RO:0002436	drug_central	Binding constant for EPHA8 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P29317	RO:0002436	drug_central	Binding constant for EPHA2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Binding constant for EPHA3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q86UE8	RO:0002436	drug_central	Binding constant for TLK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P16591	RO:0002436	drug_central	Binding constant for FER kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13555	RO:0002436	drug_central	Binding constant for CAMK2G kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q2M2I8	RO:0002436	drug_central	Binding constant for AAK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q02156	RO:0002436	drug_central	Binding constant for PRKCE kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q16513	RO:0002436	drug_central	Binding constant for PKN2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central	Binding constant for CSK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q7L7X3	RO:0002436	drug_central	Binding constant for TAOK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q59H18	RO:0002436	drug_central	Binding constant for TNNI3K kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	Binding constant for ERBB2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P15735	RO:0002436	drug_central	Binding constant for PHKG2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central	Binding constant for TRKA kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13464	RO:0002436	drug_central	Binding constant for ROCK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O14578	RO:0002436	drug_central	Binding constant for CIT kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P51812	RO:0002436	drug_central	Binding constant for RSK2(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8NEV4	RO:0002436	drug_central	Binding constant for MYO3A kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8NFD2	RO:0002436	drug_central	Binding constant for ANKK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding constant for HIPK4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O00506	RO:0002436	drug_central	Binding constant for YSK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q15746	RO:0002436	drug_central	Binding constant for MYLK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9Y6R4	RO:0002436	drug_central	Binding constant for MAP3K4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding constant for MINK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8N752	RO:0002436	drug_central	Binding constant for CSNK1A1L kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q5S007	RO:0002436	drug_central	Binding constant for LRRK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9NRP7	RO:0002436	drug_central	Binding constant for STK36 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9NWZ3	RO:0002436	drug_central	Binding constant for IRAK4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(D816V) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central	Binding constant for ERBB4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q16584	RO:0002436	drug_central	Binding constant for MLK3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Binding constant for EPHA6 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P42679	RO:0002436	drug_central	Binding constant for CTK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q96RR4	RO:0002436	drug_central	Binding constant for CAMKK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q99640	RO:0002436	drug_central	Binding constant for PKMYT1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9HAZ1	RO:0002436	drug_central	Binding constant for CLK4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q04912	RO:0002436	drug_central	Binding constant for MST1R kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Binding constant for TYK2(JH2domain-pseudokinase) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13153	RO:0002436	drug_central	Binding constant for PAK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13043	RO:0002436	drug_central	Binding constant for MST1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13188	RO:0002436	drug_central	Binding constant for MST2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8IU85	RO:0002436	drug_central	Binding constant for CAMK1D kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UL54	RO:0002436	drug_central	Binding constant for TAOK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P51955	RO:0002436	drug_central	Binding constant for NEK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13131	RO:0002436	drug_central	Binding constant for AMPK-alpha1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q15349	RO:0002436	drug_central	Binding constant for RSK3(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P51813	RO:0002436	drug_central	Binding constant for BMX kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P54756	RO:0002436	drug_central	Binding constant for EPHA5 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8IYT8	RO:0002436	drug_central	Binding constant for ULK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P54764	RO:0002436	drug_central	Binding constant for EPHA4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P06748	RO:0002436	drug_central	Inhibition of NPM/ALK L256T mutant kinase activity in BaF3 cells by radioenzymatic assay	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Inhibition of NPM/ALK L256T mutant kinase activity in BaF3 cells by radioenzymatic assay	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q16816	RO:0002436	drug_central	Binding constant for PHKG1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central	Binding constant for EPHB1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central	Binding constant for TNK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q00536	RO:0002436	drug_central	Binding constant for PCTK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q05397	RO:0002436	drug_central	Binding constant for FAK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central	Binding constant for TRKC kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P43403	RO:0002436	drug_central	Binding constant for ZAP70 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UQM7	RO:0002436	drug_central	Binding constant for CAMK2A kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P32298	RO:0002436	drug_central	Binding constant for GRK4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding constant for MAP3K2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding constant for ULK3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9BQI3	RO:0002436	drug_central	Binding constant for EIF2AK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9P289	RO:0002436	drug_central	Binding constant for MST4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9NYY3	RO:0002436	drug_central	Binding constant for PLK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13873	RO:0002436	drug_central	Binding constant for BMPR2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q14289	RO:0002436	drug_central	Binding constant for PYK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding constant for TIE2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q14164	RO:0002436	drug_central	Binding constant for IKK-epsilon kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O14733	RO:0002436	drug_central	Binding constant for MKK7 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O14936	RO:0002436	drug_central	Binding constant for CASK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q6XUX3	RO:0002436	drug_central	Binding constant for RIPK5 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P21860	RO:0002436	drug_central	Binding constant for ERBB3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for SIK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9H2K8	RO:0002436	drug_central	Binding constant for TAOK3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9H3Y6	RO:0002436	drug_central	Binding constant for SRMS kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P48729	RO:0002436	drug_central	Binding constant for CSNK1A1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13233	RO:0002436	drug_central	Binding constant for MAP3K1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P50613	RO:0002436	drug_central	Binding constant for CDK7 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q8WU08	RO:0002436	drug_central	Binding constant for YANK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9Y2K2	RO:0002436	drug_central	Binding constant for QSK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central	Binding constant for ROCK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9Y6E0	RO:0002436	drug_central	Binding constant for MST3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Inhibition of Abl kinase	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Inhibition of Abl kinase	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P0C1S8	RO:0002436	drug_central	Binding constant for WEE2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P57058	RO:0002436	drug_central	Binding constant for HUNK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central	Binding constant for DDR2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q05655	RO:0002436	drug_central	Binding constant for PRKCD kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9C098	RO:0002436	drug_central	Binding constant for DCAMKL3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O94921	RO:0002436	drug_central	Binding constant for PFTK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9P2K8	RO:0002436	drug_central	Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(M918T) kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q09013	RO:0002436	drug_central	Binding constant for DMPK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O95819	RO:0002436	drug_central	Binding constant for MAP4K4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13177	RO:0002436	drug_central	Binding constant for PAK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q06418	RO:0002436	drug_central	Binding constant for TYRO3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P07332	RO:0002436	drug_central	Binding constant for FES kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P80192	RO:0002436	drug_central	Binding constant for MLK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central	Binding constant for LTK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central	Binding constant for TRKB kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P29323	RO:0002436	drug_central	Binding constant for EPHB2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central	Binding constant for MEK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P45985	RO:0002436	drug_central	Binding constant for MEK4 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UKI8	RO:0002436	drug_central	Binding constant for TLK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UPE1	RO:0002436	drug_central	Binding constant for SRPK3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q86Y07	RO:0002436	drug_central	Binding constant for VRK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P52564	RO:0002436	drug_central	Binding constant for MEK6 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Binding constant for ALK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P54753	RO:0002436	drug_central	Binding constant for EPHB3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q12852	RO:0002436	drug_central	Binding constant for DLK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P42680	RO:0002436	drug_central	Binding constant for TEC kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q99755	RO:0002436	drug_central	Binding constant for PIP5K1A kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding constant for MAP3K3 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Inhibition of Bcr-Abl fusion protein	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P11274	RO:0002436	drug_central	Inhibition of Bcr-Abl fusion protein	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9BRS2	RO:0002436	drug_central	Binding constant for RIOK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P23443	RO:0002436	drug_central	Binding constant for S6K1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O75385	RO:0002436	drug_central	Binding constant for ULK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9BYT3	RO:0002436	drug_central	Binding constant for STK33 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O96017	RO:0002436	drug_central	Binding constant for CHEK2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9BXA7	RO:0002436	drug_central	Binding constant for TSSK1B kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q9UBE8	RO:0002436	drug_central	Binding constant for NLK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:O14757	RO:0002436	drug_central	Binding constant for CHEK1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q16512	RO:0002436	drug_central	Binding constant for PKN1 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:P57059	RO:0002436	drug_central	Binding constant for SIK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:4359	biolink:molecularly_interacts_with	UniProtKB:Q13164	RO:0002436	drug_central	Binding constant for ERK5 kinase domain	biolink:Association
DrugCentral:4360	biolink:molecularly_interacts_with	UniProtKB:Q05193	RO:0002436	drug_central	Concentration required against dynamin-1 GTPase activity of sheep brain.	biolink:Association
DrugCentral:4361	biolink:molecularly_interacts_with	UniProtKB:P21462	RO:0002436	drug_central		biolink:Association
DrugCentral:4361	biolink:molecularly_interacts_with	UniProtKB:Q8TDU6	RO:0002436	drug_central		biolink:Association
DrugCentral:4361	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Ligand dependent recruitment of SRC1(676-700) peptide to human Farnesoid X-activated receptor by fluorescence resonance energy transfer assay	biolink:Association
DrugCentral:4365	biolink:molecularly_interacts_with	UniProtKB:P22460	RO:0002436	drug_central		biolink:Association
DrugCentral:4373	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Binding affinity against human cytosolic Carbonic anhydrase II	biolink:Association
DrugCentral:4373	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Binding affinity against human cytosolic Carbonic anhydrase IV	biolink:Association
DrugCentral:4374	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:4374	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:4374	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:4374	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Displacement of [3H]citalopram from SERT	biolink:Association
DrugCentral:4376	biolink:molecularly_interacts_with	UniProtKB:Q92952	RO:0002436	drug_central		biolink:Association
DrugCentral:4376	biolink:molecularly_interacts_with	UniProtKB:Q9UGI6	RO:0002436	drug_central	Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay	biolink:Association
DrugCentral:4376	biolink:molecularly_interacts_with	UniProtKB:P17252	RO:0002436	drug_central	Inhibition of human recombinant PKCalpha	biolink:Association
DrugCentral:4379	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central		biolink:Association
DrugCentral:4380	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:4380	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:4381	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Inhibition of the reuptake of [<sup>3</sup>H]5-HT	biolink:Association
DrugCentral:4382	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	cAMP accumulation in CHO cells expressing human beta-3 adrenergic receptor	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscle	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscle	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscle	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscle	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	Binding affinity for adenosine A1 receptor by using as [3H]CPX iradioligand n membranes from Chinese hamster ovary cells	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Binding affinity for adenosine A2a receptor by using as [3H]ZM-241385 radioligand in membranes from HEK-A2A cells	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central	Displacement of [3H]DPCPX from human recombinant adenosine A2B receptor expressed in HEK293 cell membrane	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Binding affinity for adenosine A3 receptor by displacement of specific binding of [125I]AB-MECA in membranes from CHO-A3 cells	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:P05186	RO:0002436	drug_central	Inhibition of TNSALP	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:O00329	RO:0002436	drug_central	Inhibition of PI3Kdelta (unknown origin)	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via adenosine A2 receptor in human platelet membranes.	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central	Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via adenosine A2 receptor in human platelet membranes.	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094125; PROTEIN FAMILY	biolink:Association
DrugCentral:4390	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094125; PROTEIN FAMILY	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P25025	RO:0002436	drug_central	DRUGMATRIX: Chemokine CXCR2 (IL-8B) radioligand binding (ligand: [125I] IL-8)	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P41597	RO:0002436	drug_central	DRUGMATRIX: Chemokine CCR2B  radioligand binding (ligand: [125I] MCP-1)	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:O15440	RO:0002436	drug_central		biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:O95255	RO:0002436	drug_central		biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:Q92887	RO:0002436	drug_central		biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:4392	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4399	biolink:molecularly_interacts_with	UniProtKB:P40238	RO:0002436	drug_central		biolink:Association
DrugCentral:4401	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	Binding affinity to sigma 1 receptor	biolink:Association
DrugCentral:4401	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	Displacement of [3H]GR205171 from human NK1 receptor in cortex homogenate by liquid scintillation counting	biolink:Association
DrugCentral:4410	biolink:molecularly_interacts_with	UniProtKB:P48061	RO:0002436	drug_central		biolink:Association
DrugCentral:4410	biolink:molecularly_interacts_with	UniProtKB:P51679	RO:0002436	drug_central		biolink:Association
DrugCentral:4410	biolink:molecularly_interacts_with	UniProtKB:P25106	RO:0002436	drug_central		biolink:Association
DrugCentral:4410	biolink:molecularly_interacts_with	UniProtKB:P61073	RO:0002436	drug_central	Displacement of [125I]12G5 antibody from human wild type CXCR4 expressed in COS7 cells	biolink:Association
DrugCentral:4410	biolink:molecularly_interacts_with	UniProtKB:P41597	RO:0002436	drug_central	Displacement of [125I]SDF1alpha from CCR2/CXCR4 expressed in CHOK1 cells	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:Q99720	RO:0002436	drug_central	DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin)	biolink:Association
DrugCentral:4411	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:4420	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	Biased for &beta;-arrestin signalling.	biolink:Association
DrugCentral:4425	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4425	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4425	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4425	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:4425	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:4425	biolink:molecularly_interacts_with	UniProtKB:P41968	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscle	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscle	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscle	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscle	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	Binding affinity for adenosine A1 receptor by using as [3H]CPX iradioligand n membranes from Chinese hamster ovary cells	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Binding affinity for adenosine A2a receptor by using as [3H]ZM-241385 radioligand in membranes from HEK-A2A cells	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central	Displacement of [3H]DPCPX from human recombinant adenosine A2B receptor expressed in HEK293 cell membrane	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Binding affinity for adenosine A3 receptor by displacement of specific binding of [125I]AB-MECA in membranes from CHO-A3 cells	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:P05186	RO:0002436	drug_central	Inhibition of TNSALP	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:O00329	RO:0002436	drug_central	Inhibition of PI3Kdelta (unknown origin)	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via adenosine A2 receptor in human platelet membranes.	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:P29275	RO:0002436	drug_central	Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via adenosine A2 receptor in human platelet membranes.	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:Q13370	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094125; PROTEIN FAMILY	biolink:Association
DrugCentral:4426	biolink:molecularly_interacts_with	UniProtKB:Q14432	RO:0002436	drug_central	Mechanism of Action; CHEMBL2094125; PROTEIN FAMILY	biolink:Association
DrugCentral:4427	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:4427	biolink:molecularly_interacts_with	UniProtKB:O60894	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:4427	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:4427	biolink:molecularly_interacts_with	UniProtKB:O60895	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:4427	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:4427	biolink:molecularly_interacts_with	UniProtKB:O60896	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:4427	biolink:molecularly_interacts_with	UniProtKB:P30988	RO:0002436	drug_central	IC50 values for peptides in competition for 125I-labeled salmon CT binding to COS-7 cells cotransfected with 100 ng of hCTR and 100 ng of RAMP.	biolink:Association
DrugCentral:4451	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4452	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:4452	biolink:molecularly_interacts_with	UniProtKB:P04083	RO:0002436	drug_central		biolink:Association
DrugCentral:4452	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:4454	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Mechanism of Action; CHEMBL1871; SINGLE PROTEIN	biolink:Association
DrugCentral:4456	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:4458	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central	Inhibitory concentration against Endothelin A receptor	biolink:Association
DrugCentral:4458	biolink:molecularly_interacts_with	UniProtKB:P24530	RO:0002436	drug_central	Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparation	biolink:Association
DrugCentral:4466	biolink:molecularly_interacts_with	UniProtKB:Q99873	RO:0002436	drug_central		biolink:Association
DrugCentral:4470	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central		biolink:Association
DrugCentral:4477	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Binding affinity against human cytosolic Carbonic anhydrase IV	biolink:Association
DrugCentral:4482	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095158; PROTEIN FAMILY	biolink:Association
DrugCentral:4482	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095158; PROTEIN FAMILY	biolink:Association
DrugCentral:4482	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095158; PROTEIN FAMILY	biolink:Association
DrugCentral:4482	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:4483	biolink:molecularly_interacts_with	UniProtKB:P28074	RO:0002436	drug_central	fluorogenic peptide substrate hydrolysis	biolink:Association
DrugCentral:4483	biolink:molecularly_interacts_with	UniProtKB:P07858	RO:0002436	drug_central	Inhibition of recombinant cathepsin B (unknown origin) using Z-Leu-Arg-AMC as substrate by spectrofluorometer analysis	biolink:Association
DrugCentral:4483	biolink:molecularly_interacts_with	UniProtKB:P28062	RO:0002436	drug_central	Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA	biolink:Association
DrugCentral:4484	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	Binding affinity to muscarinic M2 receptor	biolink:Association
DrugCentral:4484	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	Binding affinity to muscarinic M1 receptor	biolink:Association
DrugCentral:4484	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	Binding affinity to muscarinic M3 receptor	biolink:Association
DrugCentral:4484	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	Displacement of [3H]NMS from human muscarinic M4 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay	biolink:Association
DrugCentral:4484	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay	biolink:Association
DrugCentral:4485	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:4493	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:4496	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Displacement of [3H]spiperone from human D2short receptor stably expressed in CHO cell membranes by competitive binding assay	biolink:Association
DrugCentral:4496	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:4496	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:4497	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Mechanism of Action; CHEMBL206; SINGLE PROTEIN	biolink:Association
DrugCentral:4498	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4498	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4498	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG channel	biolink:Association
DrugCentral:4501	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:4501	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:4501	biolink:molecularly_interacts_with	UniProtKB:P33261	RO:0002436	drug_central		biolink:Association
DrugCentral:4501	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central		biolink:Association
DrugCentral:4501	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:4504	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:4505	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Binding affinity towards peroxisome proliferator activated receptor alpha (PPAR alpha)	biolink:Association
DrugCentral:4505	biolink:molecularly_interacts_with	UniProtKB:P12104	RO:0002436	drug_central	Displacement of 1-anilinonaphthalene-8-sulphonic acid from I-FABP	biolink:Association
DrugCentral:4507	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:4508	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:4508	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:4508	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:4512	biolink:molecularly_interacts_with	UniProtKB:P29218	RO:0002436	drug_central	Mechanism of Action; CHEMBL1786; SINGLE PROTEIN	biolink:Association
DrugCentral:4512	biolink:molecularly_interacts_with	UniProtKB:P49840	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095188; PROTEIN FAMILY	biolink:Association
DrugCentral:4512	biolink:molecularly_interacts_with	UniProtKB:P49841	RO:0002436	drug_central	Mechanism of Action; CHEMBL2095188; PROTEIN FAMILY	biolink:Association
DrugCentral:4514	biolink:molecularly_interacts_with	UniProtKB:Q03431	RO:0002436	drug_central		biolink:Association
DrugCentral:4514	biolink:molecularly_interacts_with	UniProtKB:P49190	RO:0002436	drug_central		biolink:Association
DrugCentral:4516	biolink:molecularly_interacts_with	UniProtKB:Q01718	RO:0002436	drug_central	125I-ACTH binding in OS3 cells expressing hMC2R wild type	biolink:Association
DrugCentral:4516	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central	Agonist activity at wild type human melanocortin-4 receptor expressed in HEK293 cells co-transfected with CRE/beta-galactosidase reporter gene assessed as stimulatory response after 6 hrs	biolink:Association
DrugCentral:4523	biolink:molecularly_interacts_with	UniProtKB:P69905	RO:0002436	drug_central		biolink:Association
DrugCentral:4523	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:4523	biolink:molecularly_interacts_with	UniProtKB:Q7RTT9	RO:0002436	drug_central		biolink:Association
DrugCentral:4523	biolink:molecularly_interacts_with	UniProtKB:Q92953	RO:0002436	drug_central		biolink:Association
DrugCentral:4523	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central	High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity model	biolink:Association
DrugCentral:4523	biolink:molecularly_interacts_with	UniProtKB:O15245	RO:0002436	drug_central	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	biolink:Association
DrugCentral:4523	biolink:molecularly_interacts_with	UniProtKB:P35498	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:4523	biolink:molecularly_interacts_with	UniProtKB:Q99250	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:4523	biolink:molecularly_interacts_with	UniProtKB:Q9NY46	RO:0002436	drug_central	Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex	biolink:Association
DrugCentral:4536	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:4554	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Transrepression activity at glucocorticoid receptor in human H292 cells assessed as inhibition of TNF-stimulated IL-6 cytokine synthesis	biolink:Association
DrugCentral:4562	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells	biolink:Association
DrugCentral:4562	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Binding affinity to D2 receptor by radioligand binding assay	biolink:Association
DrugCentral:4566	biolink:molecularly_interacts_with	UniProtKB:O75899	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111463; PROTEIN COMPLEX	biolink:Association
DrugCentral:4566	biolink:molecularly_interacts_with	UniProtKB:Q9UBS5	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111463; PROTEIN COMPLEX	biolink:Association
DrugCentral:4569	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:4573	biolink:molecularly_interacts_with	UniProtKB:P00374	RO:0002436	drug_central	Inhibition of human DHFR assessed as oxidation of NADPH using dihydrofolate as substrate pre-incubated for 10 mins before substrate addition by spectrophotometry	biolink:Association
DrugCentral:4588	biolink:molecularly_interacts_with	UniProtKB:Q9NR82	RO:0002436	drug_central		biolink:Association
DrugCentral:4588	biolink:molecularly_interacts_with	UniProtKB:P56696	RO:0002436	drug_central		biolink:Association
DrugCentral:4588	biolink:molecularly_interacts_with	UniProtKB:O43526	RO:0002436	drug_central		biolink:Association
DrugCentral:4601	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central	Inhibition of MRP1	biolink:Association
DrugCentral:4601	biolink:molecularly_interacts_with	UniProtKB:Q16678	RO:0002436	drug_central	Inhibition of human CYP1B1 by EROD assay	biolink:Association
DrugCentral:4605	biolink:molecularly_interacts_with	UniProtKB:P14735	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Counterscreen for IDE activators: Fluorescence polarization-based biochemical high throughput dose response assay for activators of recombinant IDE. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493087, AID493124, AID588439, AID588440, AID588442]	biolink:Association
DrugCentral:4606	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action; CHEMBL2034; SINGLE PROTEIN	biolink:Association
DrugCentral:4608	biolink:molecularly_interacts_with	UniProtKB:P18031	RO:0002436	drug_central	Inhibition of human PTPase 1B	biolink:Association
DrugCentral:4609	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Mechanism of Action; CHEMBL1871; SINGLE PROTEIN	biolink:Association
DrugCentral:4611	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay	biolink:Association
DrugCentral:4611	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay	biolink:Association
DrugCentral:4611	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central	Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay	biolink:Association
DrugCentral:4611	biolink:molecularly_interacts_with	UniProtKB:P15090	RO:0002436	drug_central	Binding affinity against Adipocyte lipid binding protein	biolink:Association
DrugCentral:4616	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:4616	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central		biolink:Association
DrugCentral:4616	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central		biolink:Association
DrugCentral:4616	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation counting	biolink:Association
DrugCentral:4618	biolink:molecularly_interacts_with	UniProtKB:P05413	RO:0002436	drug_central	Binding affinity to human FABP3 expressed in Escherichia coli BL21 (DE3) in DMPC liposomes by surface plasmon resonance analysis	biolink:Association
DrugCentral:4618	biolink:molecularly_interacts_with	UniProtKB:P11511	RO:0002436	drug_central	Inhibition of aromatase in human placental microsomes by radiometric method	biolink:Association
DrugCentral:4618	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate assessed as formation of prostanoid products preincubated for 10 mins prior to substrate addition measured after 2 mins by Ellman's method	biolink:Association
DrugCentral:4618	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Binding affinity to PPARgamma	biolink:Association
DrugCentral:4618	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Binding affinity to PPAR-alpha (unknown origin) by fluorescence-based assay	biolink:Association
DrugCentral:4618	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central	Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay	biolink:Association
DrugCentral:4618	biolink:molecularly_interacts_with	UniProtKB:P13726	RO:0002436	drug_central	Inhibition of amidolytic activity of human tissue factor/human factor 7a	biolink:Association
DrugCentral:4621	biolink:molecularly_interacts_with	UniProtKB:P04818	RO:0002436	drug_central		biolink:Association
DrugCentral:4622	biolink:molecularly_interacts_with	UniProtKB:P25092	RO:0002436	drug_central	competitive radioligand binding assay with [125I]-STa	biolink:Association
DrugCentral:4624	biolink:molecularly_interacts_with	UniProtKB:P15121	RO:0002436	drug_central	Inhibition of aldose reductase	biolink:Association
DrugCentral:4627	biolink:molecularly_interacts_with	UniProtKB:P32238	RO:0002436	drug_central	Displacement of radiolabeled CCK-8s from human CCK1 receptor	biolink:Association
DrugCentral:4627	biolink:molecularly_interacts_with	UniProtKB:P32239	RO:0002436	drug_central	Tested for the inhibition of [3H]pCCK-8 binding to Cholecystokinin type B receptor in guinea pig brain	biolink:Association
DrugCentral:4628	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Displacement of [3H]R1881 from AR in human MDA-MB-453 cells	biolink:Association
DrugCentral:4630	biolink:molecularly_interacts_with	UniProtKB:P14324	RO:0002436	drug_central	Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 mins	biolink:Association
DrugCentral:4631	biolink:molecularly_interacts_with	UniProtKB:P16066	RO:0002436	drug_central		biolink:Association
DrugCentral:4631	biolink:molecularly_interacts_with	UniProtKB:O75343	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:4631	biolink:molecularly_interacts_with	UniProtKB:P33402	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:4631	biolink:molecularly_interacts_with	UniProtKB:Q02108	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:4631	biolink:molecularly_interacts_with	UniProtKB:Q02153	RO:0002436	drug_central	Mechanism of Action; CHEMBL2111348; PROTEIN COMPLEX GROUP	biolink:Association
DrugCentral:4633	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Inhibition of Src	biolink:Association
DrugCentral:4634	biolink:molecularly_interacts_with	UniProtKB:Q02127	RO:0002436	drug_central	Inhibition of human recombinant DHODH	biolink:Association
DrugCentral:4637	biolink:molecularly_interacts_with	UniProtKB:Q99895	RO:0002436	drug_central	Inhibitory activity against chymotrypsinogen	biolink:Association
DrugCentral:4637	biolink:molecularly_interacts_with	UniProtKB:P16278	RO:0002436	drug_central	Inhibition of Beta-galactosidase	biolink:Association
DrugCentral:4641	biolink:molecularly_interacts_with	UniProtKB:Q96RJ0	RO:0002436	drug_central	Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assay	biolink:Association
DrugCentral:4642	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay	biolink:Association
DrugCentral:4642	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay	biolink:Association
DrugCentral:4642	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central	Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay	biolink:Association
DrugCentral:4647	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central		biolink:Association
DrugCentral:4648	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	Inhibition of COX1	biolink:Association
DrugCentral:4654	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central		biolink:Association
DrugCentral:4654	biolink:molecularly_interacts_with	UniProtKB:P15056	RO:0002436	drug_central	Inhibition of wild-type B-Raf	biolink:Association
DrugCentral:4654	biolink:molecularly_interacts_with	UniProtKB:P34913	RO:0002436	drug_central	Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carbonate conversion to 6-methoxy-2-naphthaldehyde preincubated for 5 mins prior to substrate addition by fluorescence assay	biolink:Association
DrugCentral:4654	biolink:molecularly_interacts_with	UniProtKB:P23415	RO:0002436	drug_central		biolink:Association
DrugCentral:4659	biolink:molecularly_interacts_with	UniProtKB:O75762	RO:0002436	drug_central	inhibition of calcium response evoked by the TRPA1 agonist AITC (10uM) in IMR90	biolink:Association
DrugCentral:4663	biolink:molecularly_interacts_with	UniProtKB:O00748	RO:0002436	drug_central	Inhibition constant against human intestinal carboxylesterase (hiCE) expressed in Sf21 cells using 3 mM o-NPA	biolink:Association
DrugCentral:4663	biolink:molecularly_interacts_with	UniProtKB:P23141	RO:0002436	drug_central	Inhibition constant against human liver carboxylesterase (hCE1) expressed in Sf21 cells using 3 mM o-NPA	biolink:Association
DrugCentral:4664	biolink:molecularly_interacts_with	UniProtKB:P14920	RO:0002436	drug_central	Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serine	biolink:Association
DrugCentral:4667	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine)	biolink:Association
DrugCentral:4667	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4667	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4667	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4667	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central	DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine)	biolink:Association
DrugCentral:4667	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	biolink:Association
DrugCentral:4671	biolink:molecularly_interacts_with	UniProtKB:Q9Y2I1	RO:0002436	drug_central		biolink:Association
DrugCentral:4673	biolink:molecularly_interacts_with	UniProtKB:P41146	RO:0002436	drug_central		biolink:Association
DrugCentral:4673	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Binding affinity to kappa opioid receptor	biolink:Association
DrugCentral:4673	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central		biolink:Association
DrugCentral:4673	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:4676	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Binding affinity to sarin-inhibited hemoglobin free human erythrocyte ghost acetylcholinesterase using acetylthiocholineiodide as substrate measured up to 1 hr by Ellman method	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:Q969S8	RO:0002436	drug_central	Competitive inhibition of HDAC10 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:Q96DB2	RO:0002436	drug_central	Competitive inhibition of HDAC11 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:Q9BY41	RO:0002436	drug_central	Competitive inhibition of HDAC8 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:Q9UKV0	RO:0002436	drug_central	Competitive inhibition of HDAC9 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:Q9UBN7	RO:0002436	drug_central	Competitive inhibition of HDAC6 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central	Inhibition of human HDAC1	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:P56524	RO:0002436	drug_central	Competitive inhibition of HDAC4 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central	Inhibition of human HDAC3	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central	Inhibition of human HDAC2	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:Q9UQL6	RO:0002436	drug_central	Competitive inhibition of HDAC5 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4682	biolink:molecularly_interacts_with	UniProtKB:Q8WUI4	RO:0002436	drug_central	Competitive inhibition of HDAC7 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4683	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration method	biolink:Association
DrugCentral:4683	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration method	biolink:Association
DrugCentral:4684	biolink:molecularly_interacts_with	UniProtKB:P42261	RO:0002436	drug_central	Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-3 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluorescence imaging plate reader method	biolink:Association
DrugCentral:4684	biolink:molecularly_interacts_with	UniProtKB:P42262	RO:0002436	drug_central	Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-3 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluorescence imaging plate reader method	biolink:Association
DrugCentral:4684	biolink:molecularly_interacts_with	UniProtKB:P42263	RO:0002436	drug_central	Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-3 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluorescence imaging plate reader method	biolink:Association
DrugCentral:4684	biolink:molecularly_interacts_with	UniProtKB:P48058	RO:0002436	drug_central	Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-3 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluorescence imaging plate reader method	biolink:Association
DrugCentral:4690	biolink:molecularly_interacts_with	UniProtKB:O75469	RO:0002436	drug_central	Activation of human PXR expressed in african green monkey CV1 cells transfected with pSG5-hPXRDATG and (ER6)3-tk-CAT reporter	biolink:Association
DrugCentral:4696	biolink:molecularly_interacts_with	UniProtKB:P00797	RO:0002436	drug_central	purified human renin	biolink:Association
DrugCentral:4702	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA	biolink:Association
DrugCentral:4702	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Binding affinity to human adrenergic beta1 receptor by radioligand displacement assay	biolink:Association
DrugCentral:4702	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	biolink:Association
DrugCentral:4704	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:4706	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:4706	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4706	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4706	biolink:molecularly_interacts_with	UniProtKB:Q16881	RO:0002436	drug_central		biolink:Association
DrugCentral:4706	biolink:molecularly_interacts_with	UniProtKB:P07711	RO:0002436	drug_central	Inhibitory concentration against human liver cathepsin L	biolink:Association
DrugCentral:4710	biolink:molecularly_interacts_with	UniProtKB:P32241	RO:0002436	drug_central	inhibition of [125I]-VIP binding to membranes from CHO cells stably expressing the recombinant receptor	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central		biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(T315I)-phosphorylated kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:O15075	RO:0002436	drug_central	Binding constant for DCAMKL1 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q14012	RO:0002436	drug_central	Binding constant for CAMK1 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q9UK32	RO:0002436	drug_central	Binding constant for RSK4(Kin.Dom.2-C-terminal) kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q15418	RO:0002436	drug_central	Binding constant for RSK1(Kin.Dom.2-C-terminal) kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Inhibition of JAK2/TYK2 in human whole blood assessed as inhibition of IL-23-induced STAT-3 phosphorylation preincubated for 45 mins followed by IL-23 addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Inhibition of JAK2/TYK2 in human whole blood assessed as inhibition of IL-23-induced STAT-3 phosphorylation preincubated for 45 mins followed by IL-23 addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Inhibition of JAK1/JAK2/TYK2 in human whole blood assessed as inhibition of IL-6-induced STAT-1 phosphorylation preincubated for 45 mins followed by IL-6 addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Inhibition of JAK1/JAK2/TYK2 in human whole blood assessed as inhibition of IL-6-induced STAT-1 phosphorylation preincubated for 45 mins followed by IL-6 addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Inhibition of JAK1/JAK2/TYK2 in human whole blood assessed as inhibition of IL-6-induced STAT-1 phosphorylation preincubated for 45 mins followed by IL-6 addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Inhibition of JAK1/TYK2 in human whole blood assessed as inhibition of IFN-alpha-induced STAT-3 phosphorylation preincubated for 45 mins followed by IFN-alpha addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Inhibition of JAK1/TYK2 in human whole blood assessed as inhibition of IFN-alpha-induced STAT-3 phosphorylation preincubated for 45 mins followed by IFN-alpha addition measured after 15 mins by FACS analysis	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Inhibition of human recombinant GST-tagged JAK1 using 5-FAM-KKSRGDYMTMQIG as substrate by peptide mobility shift assay	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q8WTQ7	RO:0002436	drug_central	Binding constant for GRK7 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q16513	RO:0002436	drug_central	Binding constant for PKN2 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q13464	RO:0002436	drug_central	Binding constant for ROCK1 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q5S007	RO:0002436	drug_central	Binding constant for LRRK2(G2019S) kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q9HBH9	RO:0002436	drug_central	Binding constant for MKNK2 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Inhibition of human recombinant GST-tagged TYK2 using 5-FAM-KKSRGDYMTMQIG as substrate by peptide mobility shift assay	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q8IU85	RO:0002436	drug_central	Binding constant for CAMK1D kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q13188	RO:0002436	drug_central	Binding affinity to MST2	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q15349	RO:0002436	drug_central	Binding constant for RSK3(Kin.Dom.2-C-terminal) kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q9UQM7	RO:0002436	drug_central	Binding constant for CAMK2A kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding constant for ULK3 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central	Binding constant for ROCK2 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q05655	RO:0002436	drug_central	Binding constant for PRKCD kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q9C098	RO:0002436	drug_central	Binding affinity to DCamkL3	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(M918T) kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q09013	RO:0002436	drug_central	Binding constant for DMPK kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q13557	RO:0002436	drug_central	Binding constant for CAMK2D kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q16512	RO:0002436	drug_central	Binding constant for PKN1 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:Q13470	RO:0002436	drug_central	Binding constant for TNK1 kinase domain	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4713	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4715	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central		biolink:Association
DrugCentral:4715	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central		biolink:Association
DrugCentral:4715	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central		biolink:Association
DrugCentral:4715	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central		biolink:Association
DrugCentral:4715	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central		biolink:Association
DrugCentral:4715	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central		biolink:Association
DrugCentral:4715	biolink:molecularly_interacts_with	UniProtKB:Q04912	RO:0002436	drug_central		biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central		biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central		biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central		biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central		biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central		biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central		biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central		biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Inhibition of FLT3 in human MV4-11 cells	biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P11274	RO:0002436	drug_central	Mechanism of Action; CHEMBL5146; SINGLE PROTEIN	biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Inhibition of BCR/ABL (unknown origin)	biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P11274	RO:0002436	drug_central	Inhibition of BCR/ABL (unknown origin)	biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central		biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central		biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:P49336	RO:0002436	drug_central	CDK8/cyclin C.	biolink:Association
DrugCentral:4716	biolink:molecularly_interacts_with	UniProtKB:Q9BWU1	RO:0002436	drug_central	CDK19/cyclin C.	biolink:Association
DrugCentral:4718	biolink:molecularly_interacts_with	UniProtKB:O95838	RO:0002436	drug_central	Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay	biolink:Association
DrugCentral:4719	biolink:molecularly_interacts_with	UniProtKB:O95255	RO:0002436	drug_central		biolink:Association
DrugCentral:4719	biolink:molecularly_interacts_with	UniProtKB:Q9UNQ0	RO:0002436	drug_central		biolink:Association
DrugCentral:4719	biolink:molecularly_interacts_with	UniProtKB:P33527	RO:0002436	drug_central		biolink:Association
DrugCentral:4719	biolink:molecularly_interacts_with	UniProtKB:P11388	RO:0002436	drug_central		biolink:Association
DrugCentral:4719	biolink:molecularly_interacts_with	UniProtKB:P08183	RO:0002436	drug_central		biolink:Association
DrugCentral:4721	biolink:molecularly_interacts_with	UniProtKB:P55157	RO:0002436	drug_central		biolink:Association
DrugCentral:4727	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central		biolink:Association
DrugCentral:4728	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:4728	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central	DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid)	biolink:Association
DrugCentral:4728	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:4728	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:4728	biolink:molecularly_interacts_with	UniProtKB:P48050	RO:0002436	drug_central		biolink:Association
DrugCentral:4731	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	inhibition of GABA-induced Cl- current in human GABAA receptor expressed in Xenopus oocytes	biolink:Association
DrugCentral:4731	biolink:molecularly_interacts_with	UniProtKB:P47869	RO:0002436	drug_central	inhibition of GABA-induced Cl- current in human GABAA receptor expressed in Xenopus oocytes	biolink:Association
DrugCentral:4731	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	inhibition of GABA-induced Cl- current in human GABAA receptor expressed in Xenopus oocytes	biolink:Association
DrugCentral:4731	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	inhibition of GABA-induced Cl- current in human GABAA receptor expressed in Xenopus oocytes	biolink:Association
DrugCentral:4731	biolink:molecularly_interacts_with	UniProtKB:P18505	RO:0002436	drug_central	inhibition of GABA-induced Cl- current in human GABAA receptor expressed in Xenopus oocytes	biolink:Association
DrugCentral:4731	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	inhibition of GABA-induced Cl- current in human GABAA receptor expressed in Xenopus oocytes	biolink:Association
DrugCentral:4731	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	inhibition of GABA-induced Cl- current in human GABAA receptor expressed in Xenopus oocytes	biolink:Association
DrugCentral:4731	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	inhibition of GABA-induced Cl- current in human GABAA receptor expressed in Xenopus oocytes	biolink:Association
DrugCentral:4731	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	inhibition of GABA-induced Cl- current in human GABAA receptor expressed in Xenopus oocytes	biolink:Association
DrugCentral:4732	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	Inhibition of human AchE	biolink:Association
DrugCentral:4732	biolink:molecularly_interacts_with	UniProtKB:Q9UBE0	RO:0002436	drug_central	PUBCHEM_BIOASSAY: uHTS HTRF assay for identification of inhibitors of SUMOylation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2011, AID2018, AID2069, AID2614, AID2658]	biolink:Association
DrugCentral:4732	biolink:molecularly_interacts_with	UniProtKB:Q9UBT2	RO:0002436	drug_central	PUBCHEM_BIOASSAY: uHTS HTRF assay for identification of inhibitors of SUMOylation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2011, AID2018, AID2069, AID2614, AID2658]	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central	DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912)	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55)	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide)	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central	DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine)	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone)	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central	DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912)	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P10635	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA)	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P22748	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:Q8N1Q1	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 13 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P07451	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P35218	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 5A preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:Q9Y2D0	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 5B preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human recombinant carbonic anhydrase 6 preincubated for 15 mins to 72 hrs measured after 15 mins by stopped flow CO2 hydration method	biolink:Association
DrugCentral:4733	biolink:molecularly_interacts_with	UniProtKB:Q9NR96	RO:0002436	drug_central	PUBCHEM_BIOASSAY: Fluorescence-based cell-based high throughput dose response assay for inhibitors of TLR9-MyD88 binding. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504734, AID504750, AID540250, AID540251]	biolink:Association
DrugCentral:4744	biolink:molecularly_interacts_with	UniProtKB:P13569	RO:0002436	drug_central		biolink:Association
DrugCentral:4744	biolink:molecularly_interacts_with	UniProtKB:Q5XXA6	RO:0002436	drug_central		biolink:Association
DrugCentral:4746	biolink:molecularly_interacts_with	UniProtKB:Q96SW2	RO:0002436	drug_central	competitive titration of thalidomide with human DDB1-human CRBN (50 nM) and Cy5-thalidomide (20 nM)	biolink:Association
DrugCentral:4749	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central		biolink:Association
DrugCentral:4752	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:4752	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:4757	biolink:molecularly_interacts_with	UniProtKB:Q14145	RO:0002436	drug_central	Mechanism of Action; CHEMBL2069156; SINGLE PROTEIN	biolink:Association
DrugCentral:4757	biolink:molecularly_interacts_with	UniProtKB:Q8TDS4	RO:0002436	drug_central	Displacement of [3H]nicotinic acid from human GPR109a receptor expressed in human HEK293T cells by liquid scintillation counting	biolink:Association
DrugCentral:4758	biolink:molecularly_interacts_with	UniProtKB:P31639	RO:0002436	drug_central		biolink:Association
DrugCentral:4758	biolink:molecularly_interacts_with	UniProtKB:P13866	RO:0002436	drug_central	Inhibition of human SGLT1 expressed in CHO-K1 cells by [14C]AMG uptake assay	biolink:Association
DrugCentral:4773	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:4773	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Agonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1	biolink:Association
DrugCentral:4773	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Agonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1	biolink:Association
DrugCentral:4773	biolink:molecularly_interacts_with	UniProtKB:O43570	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:4773	biolink:molecularly_interacts_with	UniProtKB:Q9ULX7	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:4773	biolink:molecularly_interacts_with	UniProtKB:P43166	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:4773	biolink:molecularly_interacts_with	UniProtKB:Q16790	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:4773	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay	biolink:Association
DrugCentral:4778	biolink:molecularly_interacts_with	UniProtKB:P42345	RO:0002436	drug_central	Measured as dose-dependent inhibition of phosphorylation of ribosomal protein S6, a signaling protein downstream of mTOR	biolink:Association
DrugCentral:4794	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central	DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1)	biolink:Association
DrugCentral:4794	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4794	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:4794	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:4794	biolink:molecularly_interacts_with	UniProtKB:P21452	RO:0002436	drug_central	DRUGMATRIX: Tachykinin NK2  radioligand binding (ligand: [3H] SR-48968)	biolink:Association
DrugCentral:4794	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:4794	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central	DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH)	biolink:Association
DrugCentral:4797	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli	biolink:Association
DrugCentral:4797	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli	biolink:Association
DrugCentral:4799	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:4799	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central		biolink:Association
DrugCentral:4799	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:4801	biolink:molecularly_interacts_with	UniProtKB:P15056	RO:0002436	drug_central		biolink:Association
DrugCentral:4801	biolink:molecularly_interacts_with	UniProtKB:P36897	RO:0002436	drug_central	Inhibition of Alk5 in TGF-beta-stimulated human HepG2 cells assessed as decrease in Smad2 phosphorylation treated for 45 mins prior to TGF-beta stimulation measured after 60 mins by odyssey blot scanner analysis	biolink:Association
DrugCentral:4801	biolink:molecularly_interacts_with	UniProtKB:P04049	RO:0002436	drug_central		biolink:Association
DrugCentral:4802	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central		biolink:Association
DrugCentral:4802	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central		biolink:Association
DrugCentral:4804	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P46098	RO:0002436	drug_central	antagonist	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	antagonist	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central	partial agonist	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	agonist	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	inhibitor	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	Binding affinity to human beta 2 adrenergic receptor	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Binding affinity to human beta 1 adrenergic receptor	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P25021	RO:0002436	drug_central	Binding affinity to human histamine H2 receptor	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	Binding affinity to human 5HT2C receptor	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Binding affinity to human 5HT2A receptor	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Binding affinity to human histamine H1 receptor	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central	Binding affinity to human 5HT5A receptor	biolink:Association
DrugCentral:4806	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central	Binding affinity to human 5HT6 receptor	biolink:Association
DrugCentral:4807	biolink:molecularly_interacts_with	UniProtKB:Q02153	RO:0002436	drug_central	minimal effective concentration to achieve threefold stimulation of cGMP formation in a recombinant sGC-overexpressing cell line	biolink:Association
DrugCentral:4807	biolink:molecularly_interacts_with	UniProtKB:Q9NP56	RO:0002436	drug_central	radioligand binding	biolink:Association
DrugCentral:4808	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.	biolink:Association
DrugCentral:4809	biolink:molecularly_interacts_with	UniProtKB:P25101	RO:0002436	drug_central	IC50 value as determined in binding assays using membranes of Chinese hamster ovary (CHO) cells containing recombinant ETA	biolink:Association
DrugCentral:4809	biolink:molecularly_interacts_with	UniProtKB:P24530	RO:0002436	drug_central	IC50 value as determined in binding assays using membranes of Chinese hamster ovary (CHO) cells containing recombinant ETB	biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central	measured in anti-IgM stimulated Ramos human B cell line	biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	measured in anti-IgM stimulated Ramos human B cell line	biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Inhibition of ErbB1 relative to control	biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P51813	RO:0002436	drug_central	Inhibition of BMX	biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Inhibition of RET	biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:Q08881	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P42680	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central		biolink:Association
DrugCentral:4810	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central		biolink:Association
DrugCentral:4812	biolink:molecularly_interacts_with	UniProtKB:P25774	RO:0002436	drug_central	Inhibition of human cathepsin S in human JY cells assessed as p10 accumulation by fluorescence-based assay	biolink:Association
DrugCentral:4814	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	competitive binding experiments against [3H]CGP 12177 in the presence of 5'-guanylyl-imidodiphosphate	biolink:Association
DrugCentral:4814	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	competitive binding experiments against [3H]CGP 12177 in the presence of 5'-guanylyl-imidodiphosphate	biolink:Association
DrugCentral:4814	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	competitive binding experiments against [3H]CGP 12177 in the presence of 5'-guanylyl-imidodiphosphate	biolink:Association
DrugCentral:4815	biolink:molecularly_interacts_with	UniProtKB:P43220	RO:0002436	drug_central	CHO cells transfected with the human GLP-1 receptor binding affinity	biolink:Association
DrugCentral:4816	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central	radioligand binding assays in CHO cells expressing human M1, M2, or M3 receptors in a scintillation proximity assay with 0.5 nM [3H]-N-methyl scopolamine as the ligand	biolink:Association
DrugCentral:4816	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central	radioligand binding assays in CHO cells expressing human M1, M2, or M3 receptors in a scintillation proximity assay with 0.5 nM [3H]-N-methyl scopolamine as the ligand	biolink:Association
DrugCentral:4816	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central	radioligand binding assays in CHO cells expressing human M1, M2, or M3 receptors in a scintillation proximity assay with 0.5 nM [3H]-N-methyl scopolamine as the ligand	biolink:Association
DrugCentral:4816	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:4816	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:4817	biolink:molecularly_interacts_with	UniProtKB:O95342	RO:0002436	drug_central		biolink:Association
DrugCentral:4817	biolink:molecularly_interacts_with	UniProtKB:P46721	RO:0002436	drug_central		biolink:Association
DrugCentral:4817	biolink:molecularly_interacts_with	UniProtKB:Q9Y6L6	RO:0002436	drug_central		biolink:Association
DrugCentral:4820	biolink:molecularly_interacts_with	UniProtKB:P48039	RO:0002436	drug_central		biolink:Association
DrugCentral:4820	biolink:molecularly_interacts_with	UniProtKB:P49286	RO:0002436	drug_central		biolink:Association
DrugCentral:4821	biolink:molecularly_interacts_with	UniProtKB:Q01718	RO:0002436	drug_central	125I-ACTH binding in OS3 cells expressing hMC2R wild type	biolink:Association
DrugCentral:4824	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4826	biolink:molecularly_interacts_with	UniProtKB:P48357	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4829	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central	PDE4 enzyme isolated from U937 cells	biolink:Association
DrugCentral:4829	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central	Potency against recombinant human PDE4A1A isoform in a TR-FRET assay.	biolink:Association
DrugCentral:4829	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central	Potency against recombinant human PDE4C1 isoform in a TR-FRET assay.	biolink:Association
DrugCentral:4829	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central	Potency against recombinant human PDE4B1 and B2 isoforms in a TR-FRET assay.	biolink:Association
DrugCentral:4830	biolink:molecularly_interacts_with	UniProtKB:P13866	RO:0002436	drug_central	uptake of [14C] alpha-methyl glucopyranoside	biolink:Association
DrugCentral:4830	biolink:molecularly_interacts_with	UniProtKB:Q2M3M2	RO:0002436	drug_central	uptake of [14C] alpha-methyl glucopyranoside	biolink:Association
DrugCentral:4830	biolink:molecularly_interacts_with	UniProtKB:A0PJK1	RO:0002436	drug_central	uptake of [14C] mannose	biolink:Association
DrugCentral:4830	biolink:molecularly_interacts_with	UniProtKB:Q8WWX8	RO:0002436	drug_central	uptake of [14C] myo-inositol	biolink:Association
DrugCentral:4830	biolink:molecularly_interacts_with	UniProtKB:P31639	RO:0002436	drug_central	[3H]-empagliflozin kinetic binding experiment	biolink:Association
DrugCentral:4832	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4833	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central	fluorometric assay with Gly-Pro-AMC substrate	biolink:Association
DrugCentral:4833	biolink:molecularly_interacts_with	UniProtKB:Q86TI2	RO:0002436	drug_central	fluorometric assay with Gly-Pro-AMC substrate	biolink:Association
DrugCentral:4834	biolink:molecularly_interacts_with	UniProtKB:Q16739	RO:0002436	drug_central	inhibition of GlcCer synthesis in disrupted wild-type MDCK cell preparations	biolink:Association
DrugCentral:4836	biolink:molecularly_interacts_with	UniProtKB:Q01726	RO:0002436	drug_central		biolink:Association
DrugCentral:4836	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central		biolink:Association
DrugCentral:4836	biolink:molecularly_interacts_with	UniProtKB:P41968	RO:0002436	drug_central		biolink:Association
DrugCentral:4836	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central		biolink:Association
DrugCentral:4839	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central		biolink:Association
DrugCentral:4839	biolink:molecularly_interacts_with	UniProtKB:P03952	RO:0002436	drug_central	Mechanism of Action; CHEMBL2000; SINGLE PROTEIN	biolink:Association
DrugCentral:4846	biolink:molecularly_interacts_with	UniProtKB:P03952	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4848	biolink:molecularly_interacts_with	UniProtKB:P10912	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4855	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4855	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4857	biolink:molecularly_interacts_with	UniProtKB:P03372	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4857	biolink:molecularly_interacts_with	UniProtKB:Q92731	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4857	biolink:molecularly_interacts_with	UniProtKB:P08842	RO:0002436	drug_central	Inhibitory activity against steroid sulfatase (STS) desulfation of 4-MUS	biolink:Association
DrugCentral:4858	biolink:molecularly_interacts_with	UniProtKB:P34998	RO:0002436	drug_central	COS cells binding human CRF	biolink:Association
DrugCentral:4863	biolink:molecularly_interacts_with	UniProtKB:O75899	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4863	biolink:molecularly_interacts_with	UniProtKB:Q9UBS5	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4864	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	radioligand binding in HEK-293 cells	biolink:Association
DrugCentral:4864	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	radioligand binding in HEK-293 cells	biolink:Association
DrugCentral:4864	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Inhibition of human DAT	biolink:Association
DrugCentral:4865	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4865	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P08069	RO:0002436	drug_central	in vitro enzymatic activity	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	in vitro enzymatic activity	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:Q9BXA7	RO:0002436	drug_central	in vitro enzymatic activity	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	in vitro enzymatic activity	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Inhibition of ABL (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Inhibition of FLT3 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Inhibition of EGFR (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Inhibition of TEL-fused SRC (unknown origin) by cell-based assay	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of TEL-fused KDR (unknown origin) by cell-based assay	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Inhibition of FGFR3 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P22455	RO:0002436	drug_central	Inhibition of FGFR4 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Inhibition of PDGFRalpha (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Inhibition of TEL-fused MET (unknown origin) by cell-based assay	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Inhibition of JAK2 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Inhibition of JAK1 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P43405	RO:0002436	drug_central	Inhibition of SYK (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central	Inhibition of BTK (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Inhibition of TEL-fused FGR (unknown origin) by cell-based assay	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Inhibition of JAK3 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG by dofetilide binding assay	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central	Inhibition of TEL-fused TRKA (unknown origin) by cell-based assay	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Inhibition of FGFR2 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Inhibition of cKIT (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:Q9HBH9	RO:0002436	drug_central	Inhibition of MKNK2 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Inhibition of LYN (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P43403	RO:0002436	drug_central	Inhibition of ZAP70 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P24941	RO:0002436	drug_central	Inhibition of CDK2 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P08922	RO:0002436	drug_central	Inhibition of TEL-fused ROS (unknown origin) by cell-based assay	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central	Inhibition of ROCK2 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P41212	RO:0002436	drug_central	Inhibition of wild-type TEL (unknown origin) by cell-based assay	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Inhibition of RET (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Inhibition of LCK (unknown origin) after 60 mins	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central	Inhibition of TEL-fused TRKB (unknown origin) by cell-based assay	biolink:Association
DrugCentral:4866	biolink:molecularly_interacts_with	UniProtKB:P11802	RO:0002436	drug_central	Inhibition of CDK4 (unknown origin) after 60 mins	biolink:Association
DrugCentral:4867	biolink:molecularly_interacts_with	UniProtKB:P20648	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4867	biolink:molecularly_interacts_with	UniProtKB:P51164	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4870	biolink:molecularly_interacts_with	UniProtKB:P25116	RO:0002436	drug_central	antagonist	biolink:Association
DrugCentral:4875	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Inhibition of human ERG by whole cell patch clamp assay	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:P56524	RO:0002436	drug_central	histone deacetylase activity in vitro in HeLa cell extracts	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:Q969S8	RO:0002436	drug_central	Competitive inhibition of HDAC10 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:Q96DB2	RO:0002436	drug_central	Competitive inhibition of HDAC11 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:Q9BY41	RO:0002436	drug_central	Competitive inhibition of HDAC8 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:Q9UKV0	RO:0002436	drug_central	Competitive inhibition of HDAC9 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:Q9UBN7	RO:0002436	drug_central	Inhibition of human HDAC6	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central	Inhibition of human HDAC1	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central	Inhibition of human HDAC3	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central	Inhibition of human HDAC2	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:Q9UQL6	RO:0002436	drug_central	Competitive inhibition of HDAC5 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4876	biolink:molecularly_interacts_with	UniProtKB:Q8WUI4	RO:0002436	drug_central	Competitive inhibition of HDAC7 using KI-104 as substrate by fluorescence assay	biolink:Association
DrugCentral:4878	biolink:molecularly_interacts_with	UniProtKB:O00329	RO:0002436	drug_central	in vitro Invitrogen SelectScreen kinase inhibitor assay	biolink:Association
DrugCentral:4878	biolink:molecularly_interacts_with	UniProtKB:P48736	RO:0002436	drug_central	in vitro Invitrogen SelectScreen kinase inhibitor assay	biolink:Association
DrugCentral:4878	biolink:molecularly_interacts_with	UniProtKB:P42338	RO:0002436	drug_central	in vitro Invitrogen SelectScreen kinase inhibitor assay	biolink:Association
DrugCentral:4878	biolink:molecularly_interacts_with	UniProtKB:P42336	RO:0002436	drug_central	in vitro Invitrogen SelectScreen kinase inhibitor assay	biolink:Association
DrugCentral:4878	biolink:molecularly_interacts_with	UniProtKB:P78527	RO:0002436	drug_central		biolink:Association
DrugCentral:4879	biolink:molecularly_interacts_with	UniProtKB:P01008	RO:0002436	drug_central		biolink:Association
DrugCentral:4881	biolink:molecularly_interacts_with	UniProtKB:O43613	RO:0002436	drug_central	radioligand-displacement binding assay	biolink:Association
DrugCentral:4881	biolink:molecularly_interacts_with	UniProtKB:O43614	RO:0002436	drug_central	radioligand-displacement binding assay	biolink:Association
DrugCentral:4882	biolink:molecularly_interacts_with	UniProtKB:P30542	RO:0002436	drug_central	Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 90 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:4882	biolink:molecularly_interacts_with	UniProtKB:P29274	RO:0002436	drug_central	Binding affinity towards human Adenosine A2a receptor expressed in HEK293 cells using 6 nM [3H]CGS-21680	biolink:Association
DrugCentral:4882	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central	Displacement of [3H]PSB-11 from human recombinant adenosine A3 receptor expressed in CHO cells	biolink:Association
DrugCentral:4885	biolink:molecularly_interacts_with	UniProtKB:P43220	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4886	biolink:molecularly_interacts_with	UniProtKB:P16233	RO:0002436	drug_central		biolink:Association
DrugCentral:4888	biolink:molecularly_interacts_with	UniProtKB:P47989	RO:0002436	drug_central		biolink:Association
DrugCentral:4890	biolink:molecularly_interacts_with	UniProtKB:P31639	RO:0002436	drug_central		biolink:Association
DrugCentral:4890	biolink:molecularly_interacts_with	UniProtKB:P13866	RO:0002436	drug_central		biolink:Association
DrugCentral:4891	biolink:molecularly_interacts_with	UniProtKB:P31639	RO:0002436	drug_central		biolink:Association
DrugCentral:4891	biolink:molecularly_interacts_with	UniProtKB:P13866	RO:0002436	drug_central		biolink:Association
DrugCentral:4892	biolink:molecularly_interacts_with	UniProtKB:P31639	RO:0002436	drug_central		biolink:Association
DrugCentral:4892	biolink:molecularly_interacts_with	UniProtKB:P13866	RO:0002436	drug_central		biolink:Association
DrugCentral:4893	biolink:molecularly_interacts_with	UniProtKB:P19971	RO:0002436	drug_central	spectrophotometric assay; 5-nitro-2'-deoxyuridine substrate	biolink:Association
DrugCentral:4895	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central		biolink:Association
DrugCentral:4895	biolink:molecularly_interacts_with	UniProtKB:Q6V1X1	RO:0002436	drug_central		biolink:Association
DrugCentral:4895	biolink:molecularly_interacts_with	UniProtKB:Q86TI2	RO:0002436	drug_central		biolink:Association
DrugCentral:4896	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central		biolink:Association
DrugCentral:4896	biolink:molecularly_interacts_with	UniProtKB:Q6V1X1	RO:0002436	drug_central		biolink:Association
DrugCentral:4896	biolink:molecularly_interacts_with	UniProtKB:Q86TI2	RO:0002436	drug_central		biolink:Association
DrugCentral:4896	biolink:molecularly_interacts_with	UniProtKB:Q12884	RO:0002436	drug_central	Inhibition of human recombinant FAP expressed in baculovirus-infected Sf9 insect cells using H-Ala-Pro-AFC as substrate after 60 mins by fluorescence assay	biolink:Association
DrugCentral:4897	biolink:molecularly_interacts_with	UniProtKB:P00742	RO:0002436	drug_central		biolink:Association
DrugCentral:4898	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	displacement of [3H]-labelled substance P from cloned human receptor expressed in CHO cells	biolink:Association
DrugCentral:4900	biolink:molecularly_interacts_with	UniProtKB:P41231	RO:0002436	drug_central		biolink:Association
DrugCentral:4900	biolink:molecularly_interacts_with	UniProtKB:P51582	RO:0002436	drug_central		biolink:Association
DrugCentral:4901	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4902	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:4902	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central		biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central		biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central		biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central		biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P35916	RO:0002436	drug_central		biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Binding constant for JNK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central	Binding constant for MEK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(T315I)-phosphorylated kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q92772	RO:0002436	drug_central	Binding constant for CDKL2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(D835Y) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q04759	RO:0002436	drug_central	Binding constant for PRKCQ kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O15075	RO:0002436	drug_central	Binding constant for DCAMKL1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O15146	RO:0002436	drug_central	Binding constant for MUSK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q14012	RO:0002436	drug_central	Binding constant for CAMK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Binding constant for FGFR3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q8TDR2	RO:0002436	drug_central	Binding constant for STK35 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q16566	RO:0002436	drug_central	Binding constant for CAMK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Binding constant for INSR kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P22455	RO:0002436	drug_central	Binding constant for FGFR4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q96SB4	RO:0002436	drug_central	Binding constant for SRPK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O14730	RO:0002436	drug_central	Binding constant for RIOK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P49674	RO:0002436	drug_central	Binding constant for CSNK1E kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q8WXR4	RO:0002436	drug_central	Binding constant for MYO3B kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P46734	RO:0002436	drug_central	Binding constant for MEK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O75914	RO:0002436	drug_central	Binding constant for PAK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P54760	RO:0002436	drug_central	Binding constant for EPHB4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UK32	RO:0002436	drug_central	Binding constant for RSK4(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P27448	RO:0002436	drug_central	Binding constant for MARK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q15418	RO:0002436	drug_central	Binding constant for RSK1(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q52WX2	RO:0002436	drug_central	Binding constant for SBK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q6ZN16	RO:0002436	drug_central	Binding constant for MAP3K15 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9Y2H9	RO:0002436	drug_central	Binding constant for MAST1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Binding constant for JAK1(JH2domain-pseudokinase) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P48730	RO:0002436	drug_central	Binding constant for CSNK1D kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q08881	RO:0002436	drug_central	Binding constant for ITK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9H422	RO:0002436	drug_central	Binding constant for HIPK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9H2X6	RO:0002436	drug_central	Binding constant for HIPK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q14680	RO:0002436	drug_central	Binding constant for MELK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P30291	RO:0002436	drug_central	Binding constant for WEE1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central	Binding constant for BTK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O60285	RO:0002436	drug_central	Binding constant for ARK5 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q15139	RO:0002436	drug_central	Binding constant for PRKD1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O43283	RO:0002436	drug_central	Binding constant for LZK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UHD2	RO:0002436	drug_central	Binding constant for TBK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UPZ9	RO:0002436	drug_central	Binding constant for ICK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P21709	RO:0002436	drug_central	Binding constant for EPHA1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for HPK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O75460	RO:0002436	drug_central	Binding constant for ERN1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q96L34	RO:0002436	drug_central	Binding constant for MARK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O95747	RO:0002436	drug_central	Binding constant for OSR1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O94806	RO:0002436	drug_central	Binding constant for PRKD3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q96BR1	RO:0002436	drug_central	Binding constant for SGK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UEW8	RO:0002436	drug_central	Binding constant for STK39 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O43318	RO:0002436	drug_central	Binding constant for TAK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P49760	RO:0002436	drug_central	Binding constant for CLK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q8WTQ7	RO:0002436	drug_central	Binding constant for GRK7 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q86YV6	RO:0002436	drug_central	Binding constant for MYLK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q86Z02	RO:0002436	drug_central	Binding constant for HIPK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P49759	RO:0002436	drug_central	Binding constant for CLK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P33981	RO:0002436	drug_central	Binding constant for TTK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P29317	RO:0002436	drug_central	Binding constant for EPHA2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P29320	RO:0002436	drug_central	Binding constant for EPHA3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P16591	RO:0002436	drug_central	Binding constant for FER kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O75716	RO:0002436	drug_central	Binding constant for STK16 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O94768	RO:0002436	drug_central	Binding constant for DRAK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Binding constant for PLK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q2M2I8	RO:0002436	drug_central	Binding constant for AAK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q7KZI7	RO:0002436	drug_central	Binding constant for MARK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O75582	RO:0002436	drug_central	Binding constant for RPS6KA5(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P19784	RO:0002436	drug_central	Binding constant for CSNK2A2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q16513	RO:0002436	drug_central	Binding constant for PKN2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Binding constant for AURKC kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P15735	RO:0002436	drug_central	Binding constant for PHKG2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central	Binding constant for TRKA kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Binding constant for FGFR2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P51812	RO:0002436	drug_central	Binding constant for RSK2(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding constant for HIPK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q15746	RO:0002436	drug_central	Binding constant for MYLK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q02779	RO:0002436	drug_central	Binding constant for MLK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding constant for MINK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q5S007	RO:0002436	drug_central	Binding constant for LRRK2(G2019S) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9NWZ3	RO:0002436	drug_central	Binding constant for IRAK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P14616	RO:0002436	drug_central	Binding constant for INSRR kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(L576P) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9P286	RO:0002436	drug_central	Binding constant for PAK7 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UEE5	RO:0002436	drug_central	Binding constant for DRAK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q16584	RO:0002436	drug_central	Binding constant for MLK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P08069	RO:0002436	drug_central	Binding constant for IGF1R kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UF33	RO:0002436	drug_central	Binding constant for EPHA6 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q96RR4	RO:0002436	drug_central	Binding constant for CAMKK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O75676	RO:0002436	drug_central	Binding constant for RPS6KA4(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q96GD4	RO:0002436	drug_central	Binding constant for AURKB kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9HAZ1	RO:0002436	drug_central	Binding constant for CLK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UIK4	RO:0002436	drug_central	Binding constant for DAPK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Binding constant for TYK2(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13043	RO:0002436	drug_central	Binding constant for MST1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q8N5S9	RO:0002436	drug_central	Binding constant for CAMKK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q8IU85	RO:0002436	drug_central	Binding constant for CAMK1D kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13188	RO:0002436	drug_central	Binding constant for MST2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q96NX5	RO:0002436	drug_central	Binding constant for CAMK1G kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13131	RO:0002436	drug_central	Binding constant for AMPK-alpha1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q15349	RO:0002436	drug_central	Binding constant for RSK3(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q8IYT8	RO:0002436	drug_central	Binding constant for ULK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q16816	RO:0002436	drug_central	Binding constant for PHKG1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P54762	RO:0002436	drug_central	Binding constant for EPHB1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central	Binding constant for TNK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q00536	RO:0002436	drug_central	Binding constant for PCTK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q05397	RO:0002436	drug_central	Binding constant for FAK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P68400	RO:0002436	drug_central	Binding constant for CSNK2A1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central	Binding constant for TRKC kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q15831	RO:0002436	drug_central	Binding constant for LKB1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q15835	RO:0002436	drug_central	Binding constant for GRK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P43403	RO:0002436	drug_central	Binding constant for ZAP70 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q04771	RO:0002436	drug_central	Binding constant for ACVR1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9Y616	RO:0002436	drug_central	Binding constant for IRAK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UQM7	RO:0002436	drug_central	Binding constant for CAMK2A kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P32298	RO:0002436	drug_central	Binding constant for GRK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding constant for MAP3K2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P24941	RO:0002436	drug_central	Binding constant for CDK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding constant for ULK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P42684	RO:0002436	drug_central	Binding constant for ABL2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9P0L2	RO:0002436	drug_central	Binding constant for MARK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9P289	RO:0002436	drug_central	Binding constant for MST4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13873	RO:0002436	drug_central	Binding constant for BMPR2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q14289	RO:0002436	drug_central	Binding constant for PYK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9NRM7	RO:0002436	drug_central	Binding constant for LATS2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O15111	RO:0002436	drug_central	Binding constant for IKK-alpha kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding constant for TIE2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q14164	RO:0002436	drug_central	Binding constant for IKK-epsilon kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9Y463	RO:0002436	drug_central	Binding constant for DYRK1B kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13523	RO:0002436	drug_central	Binding constant for PRP4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P08922	RO:0002436	drug_central	Binding constant for ROS1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P45983	RO:0002436	drug_central	Binding constant for JNK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for SIK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P50613	RO:0002436	drug_central	Binding constant for CDK7 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9Y6E0	RO:0002436	drug_central	Binding constant for MST3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P54646	RO:0002436	drug_central	Binding constant for AMPK-alpha2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P0C264	RO:0002436	drug_central	Binding constant for SgK110 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q16832	RO:0002436	drug_central	Binding constant for DDR2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q00537	RO:0002436	drug_central	Binding constant for PCTK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O43293	RO:0002436	drug_central	Binding constant for DAPK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P37023	RO:0002436	drug_central	Binding constant for ACVRL1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P36896	RO:0002436	drug_central	Binding constant for ACVR1B kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P36897	RO:0002436	drug_central	Binding constant for TGFBR1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O96013	RO:0002436	drug_central	Binding constant for PAK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9C098	RO:0002436	drug_central	Binding constant for DCAMKL3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O94921	RO:0002436	drug_central	Binding constant for PFTK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9P2K8	RO:0002436	drug_central	Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(V804M) kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O95819	RO:0002436	drug_central	Binding constant for MAP4K4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q07002	RO:0002436	drug_central	Binding constant for PCTK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O95835	RO:0002436	drug_central	Binding constant for LATS1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13177	RO:0002436	drug_central	Binding constant for PAK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q06418	RO:0002436	drug_central	Binding constant for TYRO3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P07332	RO:0002436	drug_central	Binding constant for FES kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9H1R3	RO:0002436	drug_central	Binding constant for MYLK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P80192	RO:0002436	drug_central	Binding constant for MLK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central	Binding constant for LTK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P78356	RO:0002436	drug_central	Binding constant for PIP5K2B kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O15530	RO:0002436	drug_central	Binding constant for PDPK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9BZL6	RO:0002436	drug_central	Binding constant for PRKD2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central	Binding constant for TRKB kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P78362	RO:0002436	drug_central	Binding constant for SRPK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central	Binding constant for MEK2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P45985	RO:0002436	drug_central	Binding constant for MEK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UPE1	RO:0002436	drug_central	Binding constant for SRPK3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Binding constant for ALK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q12852	RO:0002436	drug_central	Binding constant for DLK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q32MK0	RO:0002436	drug_central	Binding constant for MLCK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13546	RO:0002436	drug_central	Binding constant for RIPK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q99755	RO:0002436	drug_central	Binding constant for PIP5K1A kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding constant for MAP3K3 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9BRS2	RO:0002436	drug_central	Binding constant for RIOK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P11802	RO:0002436	drug_central	Binding constant for CDK4-cyclinD1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P23443	RO:0002436	drug_central	Binding constant for S6K1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O75385	RO:0002436	drug_central	Binding constant for ULK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9BYT3	RO:0002436	drug_central	Binding constant for STK33 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q9BXA7	RO:0002436	drug_central	Binding constant for TSSK1B kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P49841	RO:0002436	drug_central	Binding constant for GSK3B kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:O14757	RO:0002436	drug_central	Binding constant for CHEK1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P49840	RO:0002436	drug_central	Binding constant for GSK3A kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13976	RO:0002436	drug_central	Binding constant for PRKG1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P57078	RO:0002436	drug_central	Binding constant for RIPK4 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q16512	RO:0002436	drug_central	Binding constant for PKN1 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:P57059	RO:0002436	drug_central	Binding constant for SIK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13164	RO:0002436	drug_central	Binding constant for ERK5 kinase domain	biolink:Association
DrugCentral:4903	biolink:molecularly_interacts_with	UniProtKB:Q13470	RO:0002436	drug_central	Binding constant for TNK1 kinase domain	biolink:Association
DrugCentral:4904	biolink:molecularly_interacts_with	UniProtKB:P01375	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4905	biolink:molecularly_interacts_with	UniProtKB:P15692	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4906	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central	antagonism of angiotensin II induced contraction	biolink:Association
DrugCentral:4907	biolink:molecularly_interacts_with	UniProtKB:P09874	RO:0002436	drug_central		biolink:Association
DrugCentral:4907	biolink:molecularly_interacts_with	UniProtKB:Q9UGN5	RO:0002436	drug_central		biolink:Association
DrugCentral:4907	biolink:molecularly_interacts_with	UniProtKB:O95271	RO:0002436	drug_central		biolink:Association
DrugCentral:4907	biolink:molecularly_interacts_with	UniProtKB:Q9Y6F1	RO:0002436	drug_central	Inhibition of PARP3 (unknown origin) using activated DNA as substrate after 1 hr by streptavidin-horseradish peroxidase-based luminescence assay	biolink:Association
DrugCentral:4908	biolink:molecularly_interacts_with	UniProtKB:P22303	RO:0002436	drug_central	recombinant human AChE	biolink:Association
DrugCentral:4909	biolink:molecularly_interacts_with	UniProtKB:P31358	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4910	biolink:molecularly_interacts_with	UniProtKB:P37288	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4915	biolink:molecularly_interacts_with	UniProtKB:P15391	RO:0002436	drug_central	Binding of the single-chain Fv portion of blinatumomab to CD19.	biolink:Association
DrugCentral:4915	biolink:molecularly_interacts_with	UniProtKB:P04234	RO:0002436	drug_central	Binding of the single-chain Fv portion of blinatumomab to CD3.	biolink:Association
DrugCentral:4915	biolink:molecularly_interacts_with	UniProtKB:P07766	RO:0002436	drug_central	Binding of the single-chain Fv portion of blinatumomab to CD3.	biolink:Association
DrugCentral:4915	biolink:molecularly_interacts_with	UniProtKB:P09693	RO:0002436	drug_central	Binding of the single-chain Fv portion of blinatumomab to CD3.	biolink:Association
DrugCentral:4916	biolink:molecularly_interacts_with	UniProtKB:P49765	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4916	biolink:molecularly_interacts_with	UniProtKB:P49763	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4916	biolink:molecularly_interacts_with	UniProtKB:P15692	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4917	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central		biolink:Association
DrugCentral:4921	biolink:molecularly_interacts_with	UniProtKB:P27338	RO:0002436	drug_central	human recombinant MAO B	biolink:Association
DrugCentral:4921	biolink:molecularly_interacts_with	UniProtKB:Q15858	RO:0002436	drug_central	Inhibition of tetrodotoxin-sensitive Na+ channel at -50 mV membrane holding potential by patch-clamp electrophysiology	biolink:Association
DrugCentral:4921	biolink:molecularly_interacts_with	UniProtKB:P21397	RO:0002436	drug_central		biolink:Association
DrugCentral:4923	biolink:molecularly_interacts_with	UniProtKB:Q15116	RO:0002436	drug_central		biolink:Association
DrugCentral:4924	biolink:molecularly_interacts_with	UniProtKB:Q15116	RO:0002436	drug_central		biolink:Association
DrugCentral:4925	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4925	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4927	biolink:molecularly_interacts_with	UniProtKB:P43220	RO:0002436	drug_central		biolink:Association
DrugCentral:4928	biolink:molecularly_interacts_with	UniProtKB:P23945	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4929	biolink:molecularly_interacts_with	UniProtKB:P22888	RO:0002436	drug_central		biolink:Association
DrugCentral:4930	biolink:molecularly_interacts_with	UniProtKB:P16473	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4931	biolink:molecularly_interacts_with	UniProtKB:Q01726	RO:0002436	drug_central		biolink:Association
DrugCentral:4931	biolink:molecularly_interacts_with	UniProtKB:P41968	RO:0002436	drug_central		biolink:Association
DrugCentral:4931	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central		biolink:Association
DrugCentral:4931	biolink:molecularly_interacts_with	UniProtKB:Q01718	RO:0002436	drug_central		biolink:Association
DrugCentral:4933	biolink:molecularly_interacts_with	UniProtKB:P08887	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4933	biolink:molecularly_interacts_with	UniProtKB:P40189	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4934	biolink:molecularly_interacts_with	UniProtKB:Q16552	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4936	biolink:molecularly_interacts_with	UniProtKB:Q03431	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4937	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	time-resolved fluorescence resonance energy transfer assay to examine each compound’s ability to phosphorylate substrate peptide Biotin-EGPWLEEEEEAYGWMDF in the presence of the drug and 30 umol/L ATP	biolink:Association
DrugCentral:4937	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	TR-FRET in vitro assay ATP concentration 30uM	biolink:Association
DrugCentral:4937	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of KDR using Bio-Gastrintide as substrate by TR-FRET assay in presence of 50 uM of ATP	biolink:Association
DrugCentral:4938	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4938	biolink:molecularly_interacts_with	UniProtKB:Q13464	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4939	biolink:molecularly_interacts_with	UniProtKB:P25774	RO:0002436	drug_central	Inhibition of human cathepsin S	biolink:Association
DrugCentral:4940	biolink:molecularly_interacts_with	UniProtKB:P01589	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:P11802	RO:0002436	drug_central	Cdk4/cyclin D1	biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:Q00534	RO:0002436	drug_central	Cdk6/cyclin D2	biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:Q13627	RO:0002436	drug_central		biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:Q15418	RO:0002436	drug_central		biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Inhibition of GST-fused human FLT3 cytoplasmic domain (amino acids 564 to 993) using Ulight-JAK1 as substrate after 1 hr by TR-FRET assay	biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:P20248	RO:0002436	drug_central	Inhibition of CDK2/cyclinA (unknown origin)	biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:P24941	RO:0002436	drug_central	Inhibition of CDK2/cyclinA (unknown origin)	biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Inhibition of JAK3 (unknown origin)	biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:P11802	RO:0002436	drug_central	Inhibition of CDK4/cyclin D1 (unknown origin) using Rb as substrate after 60 mins by scintillation counting analysis in presence of [r-33P]ATP	biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:P24385	RO:0002436	drug_central	Inhibition of CDK4/cyclin D1 (unknown origin) using Rb as substrate after 60 mins by scintillation counting analysis in presence of [r-33P]ATP	biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:P24385	RO:0002436	drug_central	Inhibition of CDK6/cyclinD1 (unknown origin)	biolink:Association
DrugCentral:4941	biolink:molecularly_interacts_with	UniProtKB:Q00534	RO:0002436	drug_central	Inhibition of CDK6/cyclinD1 (unknown origin)	biolink:Association
DrugCentral:4942	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central	in vitro kinase activity at 1uM ATP	biolink:Association
DrugCentral:4942	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	in vitro kinase activity at 1uM ATP	biolink:Association
DrugCentral:4942	biolink:molecularly_interacts_with	UniProtKB:P35916	RO:0002436	drug_central	in vitro kinase activity at 1uM ATP	biolink:Association
DrugCentral:4942	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	in vitro kinase activity at 1uM ATP	biolink:Association
DrugCentral:4942	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	in vitro kinase activity at 1uM ATP	biolink:Association
DrugCentral:4942	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	in vitro kinase activity at 1uM ATP	biolink:Association
DrugCentral:4942	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	in vitro kinase activity at 1uM ATP	biolink:Association
DrugCentral:4942	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	in vitro kinase activity at 1uM ATP	biolink:Association
DrugCentral:4942	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Inhibition of RET (unknown origin)	biolink:Association
DrugCentral:4943	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central	displacement of [125I]-iodopindololreceptor in Sf9 cells expressing human recombinant beta2	biolink:Association
DrugCentral:4943	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central	displacement of [125I]-iodopindololreceptor in Sf9 cells expressing human recombinant beta2	biolink:Association
DrugCentral:4943	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	Agonist activity at human beta3 adrenoceptor transfected in CHO cells assessed as cyclic AMP accumulation after 45 mins by fluorescence polarization assay	biolink:Association
DrugCentral:4945	biolink:molecularly_interacts_with	UniProtKB:P32239	RO:0002436	drug_central		biolink:Association
DrugCentral:4949	biolink:molecularly_interacts_with	UniProtKB:Q9Y275	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4950	biolink:molecularly_interacts_with	UniProtKB:P05106	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4950	biolink:molecularly_interacts_with	UniProtKB:P08514	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4951	biolink:molecularly_interacts_with	UniProtKB:P11836	RO:0002436	drug_central	Binding affinity for clone 2F2 ((HuMax-CD20).	biolink:Association
DrugCentral:4952	biolink:molecularly_interacts_with	UniProtKB:P01584	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4953	biolink:molecularly_interacts_with	UniProtKB:P01589	RO:0002436	drug_central		biolink:Association
DrugCentral:4953	biolink:molecularly_interacts_with	UniProtKB:P14784	RO:0002436	drug_central		biolink:Association
DrugCentral:4953	biolink:molecularly_interacts_with	UniProtKB:P31785	RO:0002436	drug_central		biolink:Association
DrugCentral:4954	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central		biolink:Association
DrugCentral:4955	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central		biolink:Association
DrugCentral:4956	biolink:molecularly_interacts_with	UniProtKB:P15692	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4957	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central		biolink:Association
DrugCentral:4958	biolink:molecularly_interacts_with	UniProtKB:P16410	RO:0002436	drug_central		biolink:Association
DrugCentral:4959	biolink:molecularly_interacts_with	UniProtKB:P20701	RO:0002436	drug_central	Binding of humanized MHM24 to human CD11a on Jurkat cells.	biolink:Association
DrugCentral:4960	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4964	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central	microtubule disrupting agent auristatin E	biolink:Association
DrugCentral:4964	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central	microtubule disrupting agent auristatin E	biolink:Association
DrugCentral:4964	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central	microtubule disrupting agent auristatin E	biolink:Association
DrugCentral:4964	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	microtubule disrupting agent auristatin E	biolink:Association
DrugCentral:4964	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central	microtubule disrupting agent auristatin E	biolink:Association
DrugCentral:4964	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central	microtubule disrupting agent auristatin E	biolink:Association
DrugCentral:4964	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central	microtubule disrupting agent auristatin E	biolink:Association
DrugCentral:4964	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central	microtubule disrupting agent auristatin E	biolink:Association
DrugCentral:4964	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central	microtubule disrupting agent auristatin E	biolink:Association
DrugCentral:4964	biolink:molecularly_interacts_with	UniProtKB:P28908	RO:0002436	drug_central	antibody binding to CD30-expressing cells	biolink:Association
DrugCentral:4965	biolink:molecularly_interacts_with	UniProtKB:O14788	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4966	biolink:molecularly_interacts_with	UniProtKB:P29459	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4966	biolink:molecularly_interacts_with	UniProtKB:P29460	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4966	biolink:molecularly_interacts_with	UniProtKB:P29460	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4966	biolink:molecularly_interacts_with	UniProtKB:Q9NPF7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4967	biolink:molecularly_interacts_with	UniProtKB:P01375	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4968	biolink:molecularly_interacts_with	UniProtKB:P01375	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4969	biolink:molecularly_interacts_with	UniProtKB:P01031	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4970	biolink:molecularly_interacts_with	UniProtKB:P05556	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4970	biolink:molecularly_interacts_with	UniProtKB:P13612	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4970	biolink:molecularly_interacts_with	UniProtKB:P13612	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4970	biolink:molecularly_interacts_with	UniProtKB:P26010	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4971	biolink:molecularly_interacts_with	UniProtKB:P15692	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4972	biolink:molecularly_interacts_with	UniProtKB:P01854	RO:0002436	drug_central	<i>In vitro</i> binding affinity	biolink:Association
DrugCentral:4973	biolink:molecularly_interacts_with	UniProtKB:Q13547	RO:0002436	drug_central	HDAC enzyme inhibition assay using BSA substrate	biolink:Association
DrugCentral:4973	biolink:molecularly_interacts_with	UniProtKB:Q92769	RO:0002436	drug_central	HDAC enzyme inhibition assay using BSA substrate	biolink:Association
DrugCentral:4973	biolink:molecularly_interacts_with	UniProtKB:O15379	RO:0002436	drug_central	HDAC enzyme inhibition assay using BSA substrate	biolink:Association
DrugCentral:4973	biolink:molecularly_interacts_with	UniProtKB:Q969S8	RO:0002436	drug_central	HDAC enzyme inhibition assay using BSA substrate	biolink:Association
DrugCentral:4973	biolink:molecularly_interacts_with	UniProtKB:Q9BY41	RO:0002436	drug_central	HDAC enzyme inhibition assay using BSA substrate	biolink:Association
DrugCentral:4973	biolink:molecularly_interacts_with	UniProtKB:Q96DB2	RO:0002436	drug_central	HDAC enzyme inhibition assay using BSA substrate	biolink:Association
DrugCentral:4974	biolink:molecularly_interacts_with	UniProtKB:P01375	RO:0002436	drug_central		biolink:Association
DrugCentral:4975	biolink:molecularly_interacts_with	UniProtKB:P11836	RO:0002436	drug_central		biolink:Association
DrugCentral:4976	biolink:molecularly_interacts_with	UniProtKB:P04150	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4977	biolink:molecularly_interacts_with	UniProtKB:P05231	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4978	biolink:molecularly_interacts_with	UniProtKB:P01375	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4979	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4980	biolink:molecularly_interacts_with	UniProtKB:P20138	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4981	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4982	biolink:molecularly_interacts_with	UniProtKB:P13612	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4982	biolink:molecularly_interacts_with	UniProtKB:P26010	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4983	biolink:molecularly_interacts_with	UniProtKB:P11836	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4984	biolink:molecularly_interacts_with	UniProtKB:P11836	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4985	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4986	biolink:molecularly_interacts_with	UniProtKB:Q99062	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4987	biolink:molecularly_interacts_with	UniProtKB:Q99062	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4988	biolink:molecularly_interacts_with	UniProtKB:P21462	RO:0002436	drug_central		biolink:Association
DrugCentral:4988	biolink:molecularly_interacts_with	UniProtKB:Q8TDU6	RO:0002436	drug_central		biolink:Association
DrugCentral:4990	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central	microtubule destabilizing agent maytansine derivative	biolink:Association
DrugCentral:4990	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central	microtubule destabilizing agent maytansine derivative	biolink:Association
DrugCentral:4990	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central	microtubule destabilizing agent maytansine derivative	biolink:Association
DrugCentral:4990	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	microtubule destabilizing agent maytansine derivative	biolink:Association
DrugCentral:4990	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central	microtubule destabilizing agent maytansine derivative	biolink:Association
DrugCentral:4990	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central	microtubule destabilizing agent maytansine derivative	biolink:Association
DrugCentral:4990	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central	microtubule destabilizing agent maytansine derivative	biolink:Association
DrugCentral:4990	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central	microtubule destabilizing agent maytansine derivative	biolink:Association
DrugCentral:4990	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central	microtubule destabilizing agent maytansine derivative	biolink:Association
DrugCentral:4990	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	binding to sub-domain IV of the HER2 receptor	biolink:Association
DrugCentral:4991	biolink:molecularly_interacts_with	UniProtKB:Q99062	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:4993	biolink:molecularly_interacts_with	UniProtKB:P20648	RO:0002436	drug_central	[14C]TAK-438 binding	biolink:Association
DrugCentral:4993	biolink:molecularly_interacts_with	UniProtKB:P51164	RO:0002436	drug_central	[14C]TAK-438 binding	biolink:Association
DrugCentral:4995	biolink:molecularly_interacts_with	UniProtKB:P19235	RO:0002436	drug_central	Assay performed using recombinant human EPO	biolink:Association
DrugCentral:4996	biolink:molecularly_interacts_with	UniProtKB:P40238	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5000	biolink:molecularly_interacts_with	UniProtKB:Q8NBP7	RO:0002436	drug_central	Dissociation equilibrium constant for wild-type hPCSK9, measured using proprietary BIACore&reg; technology.	biolink:Association
DrugCentral:5001	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central	Recombinantly expressed human mu OR	biolink:Association
DrugCentral:5001	biolink:molecularly_interacts_with	UniProtKB:P41145	RO:0002436	drug_central	Recombinantly expressed human kappa OR	biolink:Association
DrugCentral:5001	biolink:molecularly_interacts_with	UniProtKB:P41143	RO:0002436	drug_central	equivalent to DPDPE in human SK-N-BE cells	biolink:Association
DrugCentral:5002	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5003	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5003	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:5005	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5006	biolink:molecularly_interacts_with	UniProtKB:Q9H244	RO:0002436	drug_central	cAMP accumulation in HORK3-expressing cells	biolink:Association
DrugCentral:5006	biolink:molecularly_interacts_with	UniProtKB:Q9BPV8	RO:0002436	drug_central		biolink:Association
DrugCentral:5007	biolink:molecularly_interacts_with	UniProtKB:P19235	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5008	biolink:molecularly_interacts_with	UniProtKB:Q99835	RO:0002436	drug_central		biolink:Association
DrugCentral:5009	biolink:molecularly_interacts_with	UniProtKB:P08069	RO:0002436	drug_central	human placental type 1 IGF receptor	biolink:Association
DrugCentral:5009	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	human placental insulin receptor	biolink:Association
DrugCentral:5010	biolink:molecularly_interacts_with	UniProtKB:P13569	RO:0002436	drug_central	human bronchial epithelial (HBE) cells with CF homozygous for the F508del CFTR mutation	biolink:Association
DrugCentral:5011	biolink:molecularly_interacts_with	UniProtKB:P01589	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5011	biolink:molecularly_interacts_with	UniProtKB:P14784	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5011	biolink:molecularly_interacts_with	UniProtKB:P31785	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5012	biolink:molecularly_interacts_with	UniProtKB:P08473	RO:0002436	drug_central		biolink:Association
DrugCentral:5013	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P50406	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P35348	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P08913	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P18089	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P08588	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P07550	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P35368	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P18825	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:5014	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central		biolink:Association
DrugCentral:5015	biolink:molecularly_interacts_with	UniProtKB:P10912	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5016	biolink:molecularly_interacts_with	UniProtKB:Q8NBP7	RO:0002436	drug_central		biolink:Association
DrugCentral:5017	biolink:molecularly_interacts_with	UniProtKB:P14778	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5017	biolink:molecularly_interacts_with	UniProtKB:Q9NPH3	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5022	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central		biolink:Association
DrugCentral:5022	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:5022	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:5022	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:5022	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:5022	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central		biolink:Association
DrugCentral:5022	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:5022	biolink:molecularly_interacts_with	UniProtKB:P47898	RO:0002436	drug_central		biolink:Association
DrugCentral:5025	biolink:molecularly_interacts_with	UniProtKB:P15509	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5025	biolink:molecularly_interacts_with	UniProtKB:P32927	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5026	biolink:molecularly_interacts_with	UniProtKB:P40189	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5026	biolink:molecularly_interacts_with	UniProtKB:Q14626	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5027	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	CHO cells expressing the human NK1 receptor	biolink:Association
DrugCentral:5031	biolink:molecularly_interacts_with	UniProtKB:P51679	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5037	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central	CHO cells, [3H]Spiperone (0.7nM)	biolink:Association
DrugCentral:5037	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	CHO cells, [3H]Spiperone (0.16nM)	biolink:Association
DrugCentral:5037	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	CHO cells, [3H]8-OH-DPAT (1.5nM)	biolink:Association
DrugCentral:5037	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	CHO-K1 cells, [3H]Ketanserine (0.5nM)	biolink:Association
DrugCentral:5037	biolink:molecularly_interacts_with	UniProtKB:P41595	RO:0002436	drug_central	CHO-K1 cells, [3H]LSD (1.2nM)	biolink:Association
DrugCentral:5037	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	CHO-K1 cells, [3H]Mesulergine (1.0nM)	biolink:Association
DrugCentral:5037	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central	CHO cells, [3H]LSD (1.5nM)	biolink:Association
DrugCentral:5037	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	CHO-1 cells, [3H]Pyrilamine (1.5nM)	biolink:Association
DrugCentral:5037	biolink:molecularly_interacts_with	UniProtKB:P25100	RO:0002436	drug_central	HEK-293 cells, [3H]Prazosin (0.6nM)	biolink:Association
DrugCentral:5037	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central	Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cells by competitive binding assay	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr))	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P28482	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P24557	RO:0002436	drug_central	DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2)	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:Q16539	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P05177	RO:0002436	drug_central	DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P04035	RO:0002436	drug_central	DRUGMATRIX: HMG-CoA Reductase enzyme inhibition (substrate: [14C]HMG-CoA)	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P27361	RO:0002436	drug_central	DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein)	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P11712	RO:0002436	drug_central	DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin)	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:O76074	RO:0002436	drug_central	DRUGMATRIX: Phosphodiesterase PDE5 enzyme inhibition (substrate: [3H]cGMP + cGMP)	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P23280	RO:0002436	drug_central	Inhibition of human CA6 using 4-nitrophenylacetate substrate by esterase assay	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P00918	RO:0002436	drug_central	Inhibition of human CA2 using 4-nitrophenylacetate substrate by esterase assay	biolink:Association
DrugCentral:5039	biolink:molecularly_interacts_with	UniProtKB:P00915	RO:0002436	drug_central	Inhibition of human CA1 using 4-nitrophenylacetate substrate by esterase assay	biolink:Association
DrugCentral:5042	biolink:molecularly_interacts_with	UniProtKB:P10912	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5044	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5046	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central		biolink:Association
DrugCentral:5046	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central		biolink:Association
DrugCentral:5047	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central	PPRE-luc transactivation assay in HepG2 cells transfected with hPPAR-alpha and hPPAR-gamma receptors	biolink:Association
DrugCentral:5047	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central	PPRE-luc transactivation assay in HepG2 cells transfected with hPPAR-alpha and hPPAR-gamma receptors	biolink:Association
DrugCentral:5048	biolink:molecularly_interacts_with	UniProtKB:Q9Y5N1	RO:0002436	drug_central	[35S]GTP-gamma-S binding in HEK-293 cells stably expressing the human H3	biolink:Association
DrugCentral:5048	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central	Displacement of [3H]pyrilamine from human H1 receptor expressed in CHO cell membrane after 120 mins by liquid scintillation counting analysis	biolink:Association
DrugCentral:5052	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5052	biolink:molecularly_interacts_with	UniProtKB:P08908	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5052	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5052	biolink:molecularly_interacts_with	UniProtKB:P35462	RO:0002436	drug_central		biolink:Association
DrugCentral:5052	biolink:molecularly_interacts_with	UniProtKB:P21917	RO:0002436	drug_central		biolink:Association
DrugCentral:5052	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central		biolink:Association
DrugCentral:5052	biolink:molecularly_interacts_with	UniProtKB:P34969	RO:0002436	drug_central		biolink:Association
DrugCentral:5052	biolink:molecularly_interacts_with	UniProtKB:P35367	RO:0002436	drug_central		biolink:Association
DrugCentral:5052	biolink:molecularly_interacts_with	UniProtKB:P28221	RO:0002436	drug_central		biolink:Association
DrugCentral:5052	biolink:molecularly_interacts_with	UniProtKB:P28222	RO:0002436	drug_central		biolink:Association
DrugCentral:5054	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5057	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5059	biolink:molecularly_interacts_with	UniProtKB:P40238	RO:0002436	drug_central	Mechanism of Action; cell proliferation; recombinant human TPO	biolink:Association
DrugCentral:5060	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:5061	biolink:molecularly_interacts_with	UniProtKB:P05113	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5062	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Inhibition of EGFR phosphorylation in double mutant cell line H1975	biolink:Association
DrugCentral:5062	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central		biolink:Association
DrugCentral:5062	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:5063	biolink:molecularly_interacts_with	UniProtKB:P28907	RO:0002436	drug_central		biolink:Association
DrugCentral:5066	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5067	biolink:molecularly_interacts_with	UniProtKB:P28074	RO:0002436	drug_central		biolink:Association
DrugCentral:5067	biolink:molecularly_interacts_with	UniProtKB:P49721	RO:0002436	drug_central		biolink:Association
DrugCentral:5067	biolink:molecularly_interacts_with	UniProtKB:P20618	RO:0002436	drug_central		biolink:Association
DrugCentral:5068	biolink:molecularly_interacts_with	UniProtKB:Q7L0J3	RO:0002436	drug_central		biolink:Association
DrugCentral:5071	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5072	biolink:molecularly_interacts_with	UniProtKB:Q9NQ25	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5075	biolink:molecularly_interacts_with	UniProtKB:Q96S37	RO:0002436	drug_central		biolink:Association
DrugCentral:5075	biolink:molecularly_interacts_with	UniProtKB:Q9NSA0	RO:0002436	drug_central		biolink:Association
DrugCentral:5077	biolink:molecularly_interacts_with	UniProtKB:P43119	RO:0002436	drug_central		biolink:Association
DrugCentral:5078	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central		biolink:Association
DrugCentral:5078	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central		biolink:Association
DrugCentral:5083	biolink:molecularly_interacts_with	UniProtKB:Q16552	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5087	biolink:molecularly_interacts_with	UniProtKB:P01589	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5087	biolink:molecularly_interacts_with	UniProtKB:P14784	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5087	biolink:molecularly_interacts_with	UniProtKB:P31785	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5088	biolink:molecularly_interacts_with	UniProtKB:P06729	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5089	biolink:molecularly_interacts_with	UniProtKB:P33681	RO:0002436	drug_central	Measuring binding of <sup>125</sup>I-labeled B7Ig fusion protein to immobilized abatacept.	biolink:Association
DrugCentral:5089	biolink:molecularly_interacts_with	UniProtKB:P42081	RO:0002436	drug_central	Measuring binding of <sup>125</sup>I-labeled B7Ig fusion protein to immobilized abatacept.	biolink:Association
DrugCentral:5091	biolink:molecularly_interacts_with	UniProtKB:P33681	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5091	biolink:molecularly_interacts_with	UniProtKB:P42081	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5093	biolink:molecularly_interacts_with	UniProtKB:P05113	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5105	biolink:molecularly_interacts_with	UniProtKB:P01584	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5105	biolink:molecularly_interacts_with	UniProtKB:P01583	RO:0002436	drug_central		biolink:Association
DrugCentral:5105	biolink:molecularly_interacts_with	UniProtKB:P18510	RO:0002436	drug_central		biolink:Association
DrugCentral:5109	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5110	biolink:molecularly_interacts_with	UniProtKB:P06280	RO:0002436	drug_central		biolink:Association
DrugCentral:5110	biolink:molecularly_interacts_with	UniProtKB:P16278	RO:0002436	drug_central		biolink:Association
DrugCentral:5110	biolink:molecularly_interacts_with	UniProtKB:P09848	RO:0002436	drug_central		biolink:Association
DrugCentral:5110	biolink:molecularly_interacts_with	UniProtKB:P35573	RO:0002436	drug_central		biolink:Association
DrugCentral:5110	biolink:molecularly_interacts_with	UniProtKB:P14410	RO:0002436	drug_central		biolink:Association
DrugCentral:5110	biolink:molecularly_interacts_with	UniProtKB:Q9HCG7	RO:0002436	drug_central		biolink:Association
DrugCentral:5110	biolink:molecularly_interacts_with	UniProtKB:P10253	RO:0002436	drug_central		biolink:Association
DrugCentral:5110	biolink:molecularly_interacts_with	UniProtKB:O43451	RO:0002436	drug_central		biolink:Association
DrugCentral:5118	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central		biolink:Association
DrugCentral:5118	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central		biolink:Association
DrugCentral:5133	biolink:molecularly_interacts_with	UniProtKB:P10415	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5133	biolink:molecularly_interacts_with	UniProtKB:Q07817	RO:0002436	drug_central		biolink:Association
DrugCentral:5133	biolink:molecularly_interacts_with	UniProtKB:Q92843	RO:0002436	drug_central		biolink:Association
DrugCentral:5137	biolink:molecularly_interacts_with	UniProtKB:P17181	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5137	biolink:molecularly_interacts_with	UniProtKB:P48551	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5139	biolink:molecularly_interacts_with	UniProtKB:P17181	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5139	biolink:molecularly_interacts_with	UniProtKB:P48551	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5140	biolink:molecularly_interacts_with	UniProtKB:P17181	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5140	biolink:molecularly_interacts_with	UniProtKB:P48551	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5141	biolink:molecularly_interacts_with	UniProtKB:P00747	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5142	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central	1 nM [3H]ketanserin binding in cell membranes	biolink:Association
DrugCentral:5142	biolink:molecularly_interacts_with	UniProtKB:P28335	RO:0002436	drug_central	3 nM [3H]mesulergine binding in cell membranes	biolink:Association
DrugCentral:5143	biolink:molecularly_interacts_with	UniProtKB:P21964	RO:0002436	drug_central		biolink:Association
DrugCentral:5144	biolink:molecularly_interacts_with	UniProtKB:P04062	RO:0002436	drug_central		biolink:Association
DrugCentral:5149	biolink:molecularly_interacts_with	UniProtKB:P22888	RO:0002436	drug_central		biolink:Association
DrugCentral:5151	biolink:molecularly_interacts_with	UniProtKB:Q9NZQ7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5155	biolink:molecularly_interacts_with	UniProtKB:Q96RI1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5155	biolink:molecularly_interacts_with	UniProtKB:Q8TDU6	RO:0002436	drug_central		biolink:Association
DrugCentral:5157	biolink:molecularly_interacts_with	UniProtKB:P19235	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5158	biolink:molecularly_interacts_with	UniProtKB:P17181	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5158	biolink:molecularly_interacts_with	UniProtKB:P48551	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5160	biolink:molecularly_interacts_with	UniProtKB:P19235	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5164	biolink:molecularly_interacts_with	UniProtKB:P17181	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5164	biolink:molecularly_interacts_with	UniProtKB:P48551	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5165	biolink:molecularly_interacts_with	UniProtKB:P19235	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5167	biolink:molecularly_interacts_with	UniProtKB:Q99062	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5169	biolink:molecularly_interacts_with	UniProtKB:P11473	RO:0002436	drug_central		biolink:Association
DrugCentral:5170	biolink:molecularly_interacts_with	UniProtKB:P19235	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5174	biolink:molecularly_interacts_with	UniProtKB:P05107	RO:0002436	drug_central	inhibition of ICAM-1 binding to LFA-1 in HuT 78 cell line	biolink:Association
DrugCentral:5174	biolink:molecularly_interacts_with	UniProtKB:P20701	RO:0002436	drug_central	inhibition of ICAM-1 binding to LFA-1 in HuT 78 cell line	biolink:Association
DrugCentral:5177	biolink:molecularly_interacts_with	UniProtKB:P04234	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5177	biolink:molecularly_interacts_with	UniProtKB:P07766	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5177	biolink:molecularly_interacts_with	UniProtKB:P09693	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5179	biolink:molecularly_interacts_with	UniProtKB:Q8NAC3	RO:0002436	drug_central		biolink:Association
DrugCentral:5179	biolink:molecularly_interacts_with	UniProtKB:Q96F46	RO:0002436	drug_central		biolink:Association
DrugCentral:5181	biolink:molecularly_interacts_with	UniProtKB:P41180	RO:0002436	drug_central	Measuring ligand induced IP<sub>1</sub> accumulation.	biolink:Association
DrugCentral:5182	biolink:molecularly_interacts_with	UniProtKB:P11532	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5183	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	BIAcore assay	biolink:Association
DrugCentral:5185	biolink:molecularly_interacts_with	UniProtKB:P30874	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5188	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central		biolink:Association
DrugCentral:5201	biolink:molecularly_interacts_with	UniProtKB:P27815	RO:0002436	drug_central		biolink:Association
DrugCentral:5201	biolink:molecularly_interacts_with	UniProtKB:Q07343	RO:0002436	drug_central		biolink:Association
DrugCentral:5201	biolink:molecularly_interacts_with	UniProtKB:Q08493	RO:0002436	drug_central		biolink:Association
DrugCentral:5201	biolink:molecularly_interacts_with	UniProtKB:Q08499	RO:0002436	drug_central		biolink:Association
DrugCentral:5201	biolink:molecularly_interacts_with	UniProtKB:P54750	RO:0002436	drug_central		biolink:Association
DrugCentral:5201	biolink:molecularly_interacts_with	UniProtKB:Q13946	RO:0002436	drug_central		biolink:Association
DrugCentral:5202	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central		biolink:Association
DrugCentral:5202	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central		biolink:Association
DrugCentral:5202	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central		biolink:Association
DrugCentral:5202	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central		biolink:Association
DrugCentral:5203	biolink:molecularly_interacts_with	UniProtKB:P09874	RO:0002436	drug_central		biolink:Association
DrugCentral:5203	biolink:molecularly_interacts_with	UniProtKB:Q9UGN5	RO:0002436	drug_central		biolink:Association
DrugCentral:5203	biolink:molecularly_interacts_with	UniProtKB:Q9Y6F1	RO:0002436	drug_central		biolink:Association
DrugCentral:5203	biolink:molecularly_interacts_with	UniProtKB:O95271	RO:0002436	drug_central		biolink:Association
DrugCentral:5203	biolink:molecularly_interacts_with	UniProtKB:Q9H2K2	RO:0002436	drug_central		biolink:Association
DrugCentral:5208	biolink:molecularly_interacts_with	UniProtKB:P25092	RO:0002436	drug_central	Stimulation of cGMP synthesis in T84 cells	biolink:Association
DrugCentral:5208	biolink:molecularly_interacts_with	UniProtKB:P01375	RO:0002436	drug_central	Binding affinity to TNF-alpha (unknown origin)	biolink:Association
DrugCentral:5209	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central		biolink:Association
DrugCentral:5210	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	HCC827 cells expressing EGFR(DEL19)	biolink:Association
DrugCentral:5211	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central		biolink:Association
DrugCentral:5211	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central		biolink:Association
DrugCentral:5211	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central		biolink:Association
DrugCentral:5211	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central		biolink:Association
DrugCentral:5211	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central	Assay used apatinib mesylate (YN968D1)	biolink:Association
DrugCentral:5214	biolink:molecularly_interacts_with	UniProtKB:P17752	RO:0002436	drug_central		biolink:Association
DrugCentral:5215	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central		biolink:Association
DrugCentral:5217	biolink:molecularly_interacts_with	UniProtKB:P36544	RO:0002436	drug_central	Binding affinity to human Nicotinic acetylcholine receptor alpha7 expressed in IMR32 cells using [3H]alpha-bungarotoxin	biolink:Association
DrugCentral:5218	biolink:molecularly_interacts_with	UniProtKB:P11802	RO:0002436	drug_central		biolink:Association
DrugCentral:5218	biolink:molecularly_interacts_with	UniProtKB:Q00534	RO:0002436	drug_central		biolink:Association
DrugCentral:5220	biolink:molecularly_interacts_with	UniProtKB:P35372	RO:0002436	drug_central		biolink:Association
DrugCentral:5221	biolink:molecularly_interacts_with	UniProtKB:Q9NZQ7	RO:0002436	drug_central		biolink:Association
DrugCentral:5222	biolink:molecularly_interacts_with	UniProtKB:P09874	RO:0002436	drug_central		biolink:Association
DrugCentral:5222	biolink:molecularly_interacts_with	UniProtKB:Q9UGN5	RO:0002436	drug_central		biolink:Association
DrugCentral:5222	biolink:molecularly_interacts_with	UniProtKB:O95271	RO:0002436	drug_central	Inhibition of human TANK1 C-terminal domain by trichloroacetic acid precipitation assay	biolink:Association
DrugCentral:5222	biolink:molecularly_interacts_with	UniProtKB:Q9Y6F1	RO:0002436	drug_central	Inhibition of human PARP3 by trichloroacetic acid precipitation assay	biolink:Association
DrugCentral:5223	biolink:molecularly_interacts_with	UniProtKB:P11836	RO:0002436	drug_central		biolink:Association
DrugCentral:5224	biolink:molecularly_interacts_with	UniProtKB:P24394	RO:0002436	drug_central	Value derived from an ELISA-based solution competition assay.	biolink:Association
DrugCentral:5226	biolink:molecularly_interacts_with	UniProtKB:Q05940	RO:0002436	drug_central		biolink:Association
DrugCentral:5227	biolink:molecularly_interacts_with	UniProtKB:Q05940	RO:0002436	drug_central		biolink:Association
DrugCentral:5229	biolink:molecularly_interacts_with	UniProtKB:P00491	RO:0002436	drug_central		biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central		biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P35916	RO:0002436	drug_central	Binding constant for FLT4 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O75914	RO:0002436	drug_central	Binding constant for full-length PAK3	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O15530	RO:0002436	drug_central	Binding affinity to PDPK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q16816	RO:0002436	drug_central	Binding affinity to PHKG1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q99755	RO:0002436	drug_central	Binding constant for full-length PIP5K1A	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9UK32	RO:0002436	drug_central	Binding constant for RPS6KA6(Kin.Dom.1 - C-terminal) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q86YV6	RO:0002436	drug_central	Binding constant for SgK085 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of recombinant GST-tagged VEGFR2 kinase domain (V789 to V1356) (unknown origin) expressed in insect Sf9 cells using polyGlu4:Tyr peptide as substrate after 120 mins by Kinase-Glo assay	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O00506	RO:0002436	drug_central	Binding constant for YSK1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P43403	RO:0002436	drug_central	Binding constant for ZAP70 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P78356	RO:0002436	drug_central	Binding constant for full-length PIP5K2B	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P22694	RO:0002436	drug_central	Binding constant for full-length PKAC-beta	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q14289	RO:0002436	drug_central	Binding constant for full-length PTK2B	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P49759	RO:0002436	drug_central	Binding constant for full-length CLK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central	Binding constant for full-length CSK	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding constant for TIE2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central	Binding constant for TNK2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central	Binding constant for TRKA kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central	Binding constant for TRKB kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central	Binding constant for TRKC kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P33981	RO:0002436	drug_central	Binding constant for TTK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P68400	RO:0002436	drug_central	Binding constant for full-length CSNK2A1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9UIK4	RO:0002436	drug_central	Binding constant for full-length DAPK2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O94768	RO:0002436	drug_central	Binding constant for full-length DRAK2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9Y463	RO:0002436	drug_central	Binding constant for full-length DYRK1B	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P49840	RO:0002436	drug_central	Binding constant for full-length GSK3A	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P49841	RO:0002436	drug_central	Binding constant for full-length GSK3B	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q14164	RO:0002436	drug_central	Binding constant for full-length IKK-epsilon	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central	Binding constant for TYK2(Kin.Dom.2/JH1 - catalytic) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P45983	RO:0002436	drug_central	Binding constant for full-length JNK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q15831	RO:0002436	drug_central	Binding constant for full-length LKB1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P27448	RO:0002436	drug_central	Binding constant for full-length MARK3	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P46734	RO:0002436	drug_central	Binding constant for full-length MEK3	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q14680	RO:0002436	drug_central	Binding constant for full-length MELK	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q2M2I8	RO:0002436	drug_central	Binding constant for AAK1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13043	RO:0002436	drug_central	Binding affinity to MST1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9P2K8	RO:0002436	drug_central	Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(T315I)-phosphorylated kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9Y616	RO:0002436	drug_central	Binding constant for IRAK3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	Binding constant for JAK2(Kin.Dom.2/JH1 - catalytic) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Binding constant for JNK3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	Binding constant for KIT(D816V) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9BRS2	RO:0002436	drug_central	Binding constant for full-length RIOK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O14730	RO:0002436	drug_central	Binding constant for full-length RIOK3	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for full-length SNF1LK2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q96SB4	RO:0002436	drug_central	Binding constant for full-length SRPK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P78362	RO:0002436	drug_central	Binding constant for full-length SRPK2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13470	RO:0002436	drug_central	Binding constant for full-length TNK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9BXA7	RO:0002436	drug_central	Binding constant for full-length TSSK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central	Binding constant for ALK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13131	RO:0002436	drug_central	Binding constant for AMPK-alpha1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P54646	RO:0002436	drug_central	Binding constant for AMPK-alpha2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q08345	RO:0002436	drug_central	Binding constant for DDR1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q09013	RO:0002436	drug_central	Binding constant for DMPK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P31749	RO:0002436	drug_central	Binding constant for AKT1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P31751	RO:0002436	drug_central	Binding constant for AKT2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O95835	RO:0002436	drug_central	Binding constant for LATS1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9NRM7	RO:0002436	drug_central	Binding constant for LATS2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central	Binding constant for LTK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9UEE5	RO:0002436	drug_central	Binding constant for DRAK1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	Binding constant for EGFR(L858R,T790M) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O60285	RO:0002436	drug_central	Binding constant for ARK5 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O14965	RO:0002436	drug_central	Inhibition of recombinant GST-tagged Aurora-A kinase domain (S123 to S401) (unknown origin) expressed in insect Sf9 cells using tetra(LRRASLG) peptide as substrate after 90 mins by Kinase-Glo assay	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	Binding affinity to PDGFRA	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central	Binding constant for PDGFRB kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P15735	RO:0002436	drug_central	Binding affinity to PHKG2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P11309	RO:0002436	drug_central	Binding constant for PIM1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q86V86	RO:0002436	drug_central	Binding constant for PIM3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P17612	RO:0002436	drug_central	Binding constant for PKAC-alpha kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for MAP4K1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q96GD4	RO:0002436	drug_central	Binding constant for AURKB kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9NSY1	RO:0002436	drug_central	Binding constant for BIKE kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q8TDC3	RO:0002436	drug_central	Binding constant for BRSK1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q8IU85	RO:0002436	drug_central	Binding constant for CAMK1D kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q96NX5	RO:0002436	drug_central	Binding constant for CAMK1G kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O95819	RO:0002436	drug_central	Binding constant for MAP4K4 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9P0L2	RO:0002436	drug_central	Binding constant for MARK1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q7KZI7	RO:0002436	drug_central	Binding constant for MARK2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q96L34	RO:0002436	drug_central	Binding constant for MARK4 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P45985	RO:0002436	drug_central	Binding constant for MEK4 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET(Y1235D) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9UQM7	RO:0002436	drug_central	Binding constant for CAMK2A kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13554	RO:0002436	drug_central	Binding constant for CAMK2B kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13557	RO:0002436	drug_central	Binding constant for CAMK2D kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13555	RO:0002436	drug_central	Binding constant for CAMK2G kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q8N5S9	RO:0002436	drug_central	Binding constant for CAMKK1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q96RR4	RO:0002436	drug_central	Binding constant for CAMKK2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9BWU1	RO:0002436	drug_central	Binding constant for CDK11 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9HBH9	RO:0002436	drug_central	Binding constant for MKNK2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P80192	RO:0002436	drug_central	Binding constant for MLK1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q02779	RO:0002436	drug_central	Binding constant for MLK2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q16584	RO:0002436	drug_central	Binding constant for MLK3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13188	RO:0002436	drug_central	Binding affinity to MST2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q15746	RO:0002436	drug_central	Binding affinity to MYLK	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O14757	RO:0002436	drug_central	Binding constant for CHEK1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P49760	RO:0002436	drug_central	Binding constant for CLK2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9HAZ1	RO:0002436	drug_central	Binding constant for CLK4 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Inhibition of human FMS expressed in growth factor dependent mouse FDC-P1 cells assessed as inhibition of FMS-mediated cell proliferation in presence human CSF1 after 48 hrs by resazurin dye reduction assay	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P53355	RO:0002436	drug_central	Binding constant for DAPK1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O43293	RO:0002436	drug_central	Binding constant for DAPK3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13153	RO:0002436	drug_central	Binding affinity to PAK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13177	RO:0002436	drug_central	Binding affinity to PAK2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P42685	RO:0002436	drug_central	Binding constant for FRK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9UQB9	RO:0002436	drug_central	Binding constant for full-length AURKC	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q8IWQ3	RO:0002436	drug_central	Binding constant for full-length BRSK2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q14012	RO:0002436	drug_central	Binding constant for full-length CAMK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P57059	RO:0002436	drug_central	Binding constant for SNF1LK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O75716	RO:0002436	drug_central	Binding constant for STK16 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P43405	RO:0002436	drug_central	Binding constant for SYK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q16512	RO:0002436	drug_central	Binding constant for PKN1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q16513	RO:0002436	drug_central	Binding constant for PKN2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O00444	RO:0002436	drug_central	Binding constant for PLK4 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q05655	RO:0002436	drug_central	Binding constant for PRKCD kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q02156	RO:0002436	drug_central	Binding constant for PRKCE kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P24723	RO:0002436	drug_central	Binding constant for PRKCH kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q04759	RO:0002436	drug_central	Binding constant for PRKCQ kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P16591	RO:0002436	drug_central	Binding constant for FER kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9BZL6	RO:0002436	drug_central	Binding constant for PRKD2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O94806	RO:0002436	drug_central	Binding constant for PRKD3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13976	RO:0002436	drug_central	Binding constant for PRKG1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13237	RO:0002436	drug_central	Binding constant for PRKG2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P19525	RO:0002436	drug_central	Binding constant for PRKR kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P07949	RO:0002436	drug_central	Binding constant for RET(V804M) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	Binding constant for FGFR1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Binding constant for FGFR2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Binding constant for FGFR3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central	Binding constant for FLT1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P08922	RO:0002436	drug_central	Binding constant for ROS1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q15418	RO:0002436	drug_central	Binding affinity to RPS6KA4(Kin.Dom.1-N-terminal)	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q15349	RO:0002436	drug_central	Binding affinity to RPS6KA5(Kin.Dom.1-N-terminal)	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P51812	RO:0002436	drug_central	Binding constant for RPS6KA3(Kin.Dom.1 - N-terminal) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O75676	RO:0002436	drug_central	Binding constant for RPS6KA4(Kin.Dom.1 - C-terminal) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O75582	RO:0002436	drug_central	Binding constant for RPS6KA5(Kin.Dom.1 - C-terminal) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13627	RO:0002436	drug_central	Binding affinity to DYRK1A	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding affinity to EPHB6	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central	Binding affinity to ERBB4	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O75460	RO:0002436	drug_central	Binding affinity to ERN1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q15835	RO:0002436	drug_central	Binding affinity to GRK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P32298	RO:0002436	drug_central	Binding affinity to GRK4	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q8WTQ7	RO:0002436	drug_central	Binding affinity to GRK7	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9H2X6	RO:0002436	drug_central	Binding affinity to HIPK2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9H422	RO:0002436	drug_central	Binding affinity to HIPK3	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding affinity to HIPK4	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P57058	RO:0002436	drug_central	Binding affinity to HUNK	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O15111	RO:0002436	drug_central	Binding affinity to IKK-alpha	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central	Binding affinity to JH1 catalytic domain JAK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O43283	RO:0002436	drug_central	Binding affinity to LZK	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding affinity to MAP3K2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding affinity to MAP3K3	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding affinity to MAP4K2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding affinity to MINK	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O00750	RO:0002436	drug_central	Binding affinity to PIK3C2B	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O75747	RO:0002436	drug_central	Binding affinity to PIK3C2G	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P17252	RO:0002436	drug_central	Binding affinity to PKAC-alpha	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O43172	RO:0002436	drug_central	Binding affinity to PRP4	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9Y2K2	RO:0002436	drug_central	Binding affinity to QSK	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9BVS4	RO:0002436	drug_central	Binding affinity to RIOK2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13464	RO:0002436	drug_central	Binding affinity to ROCK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central	Binding affinity to ROCK2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9UPE1	RO:0002436	drug_central	Binding affinity to SRPK3	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O43318	RO:0002436	drug_central	Binding affinity to TAK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9UHD2	RO:0002436	drug_central	Binding affinity to TBK1	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9H2K2	RO:0002436	drug_central	Binding affinity to TNK2	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q6PHR2	RO:0002436	drug_central	Binding affinity to ULK3	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding affinity to YSK4	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q8WU08	RO:0002436	drug_central	Binding constant for YANK1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:O14920	RO:0002436	drug_central	Binding constant for IKK-beta kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P52564	RO:0002436	drug_central	Binding constant for MEK6 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P23443	RO:0002436	drug_central	Binding constant for S6K1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P30291	RO:0002436	drug_central	Binding constant for WEE1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q13523	RO:0002436	drug_central	Binding constant for PRP4 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P49761	RO:0002436	drug_central	Binding constant for CLK3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9Y243	RO:0002436	drug_central	Binding constant for AKT3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P42336	RO:0002436	drug_central	Binding constant for PIK3CA(H1047L) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9P1W9	RO:0002436	drug_central	Binding constant for PIM2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q96BR1	RO:0002436	drug_central	Binding constant for SGK3 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9UPZ9	RO:0002436	drug_central	Binding constant for ICK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9Y2H9	RO:0002436	drug_central	Binding constant for MAST1 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q9BYT3	RO:0002436	drug_central	Binding constant for STK33 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:P45984	RO:0002436	drug_central	Binding constant for JNK2 kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q32MK0	RO:0002436	drug_central	Binding constant for MLCK kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q5S007	RO:0002436	drug_central	Binding constant for LRRK2(G2019S) kinase domain	biolink:Association
DrugCentral:5231	biolink:molecularly_interacts_with	UniProtKB:Q6XUX3	RO:0002436	drug_central	Binding constant for RIPK5 kinase domain	biolink:Association
DrugCentral:5232	biolink:molecularly_interacts_with	UniProtKB:Q03431	RO:0002436	drug_central		biolink:Association
DrugCentral:5233	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central		biolink:Association
DrugCentral:5233	biolink:molecularly_interacts_with	UniProtKB:P08922	RO:0002436	drug_central		biolink:Association
DrugCentral:5233	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central		biolink:Association
DrugCentral:5233	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central		biolink:Association
DrugCentral:5233	biolink:molecularly_interacts_with	UniProtKB:P08069	RO:0002436	drug_central		biolink:Association
DrugCentral:5233	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central		biolink:Association
DrugCentral:5234	biolink:molecularly_interacts_with	UniProtKB:Q9NZQ7	RO:0002436	drug_central		biolink:Association
DrugCentral:5235	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central		biolink:Association
DrugCentral:5235	biolink:molecularly_interacts_with	UniProtKB:P08138	RO:0002436	drug_central		biolink:Association
DrugCentral:5237	biolink:molecularly_interacts_with	UniProtKB:P08887	RO:0002436	drug_central		biolink:Association
DrugCentral:5237	biolink:molecularly_interacts_with	UniProtKB:P40189	RO:0002436	drug_central		biolink:Association
DrugCentral:5239	biolink:molecularly_interacts_with	UniProtKB:P27487	RO:0002436	drug_central		biolink:Association
DrugCentral:5240	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:5240	biolink:molecularly_interacts_with	UniProtKB:P23219	RO:0002436	drug_central		biolink:Association
DrugCentral:5241	biolink:molecularly_interacts_with	UniProtKB:P00742	RO:0002436	drug_central		biolink:Association
DrugCentral:5241	biolink:molecularly_interacts_with	UniProtKB:Q12809	RO:0002436	drug_central	Binding affinity to human ERG	biolink:Association
DrugCentral:5245	biolink:molecularly_interacts_with	UniProtKB:P23945	RO:0002436	drug_central		biolink:Association
DrugCentral:5246	biolink:molecularly_interacts_with	UniProtKB:P29460	RO:0002436	drug_central		biolink:Association
DrugCentral:5246	biolink:molecularly_interacts_with	UniProtKB:Q9NPF7	RO:0002436	drug_central		biolink:Association
DrugCentral:5247	biolink:molecularly_interacts_with	UniProtKB:P20273	RO:0002436	drug_central		biolink:Association
DrugCentral:5248	biolink:molecularly_interacts_with	UniProtKB:Q07869	RO:0002436	drug_central		biolink:Association
DrugCentral:5248	biolink:molecularly_interacts_with	UniProtKB:P37231	RO:0002436	drug_central		biolink:Association
DrugCentral:5248	biolink:molecularly_interacts_with	UniProtKB:Q03181	RO:0002436	drug_central		biolink:Association
DrugCentral:5250	biolink:molecularly_interacts_with	UniProtKB:P35354	RO:0002436	drug_central		biolink:Association
DrugCentral:5251	biolink:molecularly_interacts_with	UniProtKB:P48735	RO:0002436	drug_central	inhibition of 2HG production by the IDH2(R140Q) homodimer	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central		biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central		biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central		biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Inhibition of human VEGFR2 in presence of 1 uM ATP	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P00519	RO:0002436	drug_central	Binding constant for ABL1(Q252H)-phosphorylated kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central	Binding constant for CSF1R kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P16591	RO:0002436	drug_central	Binding constant for FER kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P09769	RO:0002436	drug_central	Binding constant for FGR kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O14976	RO:0002436	drug_central	Binding constant for GAK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P06239	RO:0002436	drug_central	Binding constant for LCK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P12931	RO:0002436	drug_central	Binding constant for SRC kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P35590	RO:0002436	drug_central	Binding constant for TIE1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P07947	RO:0002436	drug_central	Binding constant for YES kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O94806	RO:0002436	drug_central	Binding constant for PRKD3 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9Y6R4	RO:0002436	drug_central	Binding constant for MAP3K4 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O94804	RO:0002436	drug_central	Binding constant for LOK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q00536	RO:0002436	drug_central	Binding constant for PCTK1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q13188	RO:0002436	drug_central	Binding constant for MST2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q13043	RO:0002436	drug_central	Binding constant for MST1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q12852	RO:0002436	drug_central	Binding constant for DLK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O00506	RO:0002436	drug_central	Binding constant for YSK1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9Y4K4	RO:0002436	drug_central	Binding constant for MAP4K5 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9Y2U5	RO:0002436	drug_central	Binding constant for MAP3K2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P14616	RO:0002436	drug_central	Binding constant for INSRR kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9H2G2	RO:0002436	drug_central	Binding constant for SLK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q14680	RO:0002436	drug_central	Binding constant for MELK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O60285	RO:0002436	drug_central	Binding constant for ARK5 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9Y2H9	RO:0002436	drug_central	Binding constant for MAST1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9UKE5	RO:0002436	drug_central	Binding constant for TNIK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9H0K1	RO:0002436	drug_central	Binding constant for SIK2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9NRP7	RO:0002436	drug_central	Binding constant for STK36 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9H2K8	RO:0002436	drug_central	Binding constant for TAOK3 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9BZL6	RO:0002436	drug_central	Binding constant for PRKD2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9P289	RO:0002436	drug_central	Binding constant for MST4 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9NQU5	RO:0002436	drug_central	Binding constant for PAK6 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q8IU85	RO:0002436	drug_central	Binding constant for CAMK1D kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q15349	RO:0002436	drug_central	Binding constant for RSK3(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q56UN5	RO:0002436	drug_central	Binding constant for YSK4 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central	Binding constant for MEK2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9BYT3	RO:0002436	drug_central	Binding constant for STK33 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9H093	RO:0002436	drug_central	Binding constant for SNARK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P80192	RO:0002436	drug_central	Binding constant for MLK1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q8TDR2	RO:0002436	drug_central	Binding constant for STK35 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9NYL2	RO:0002436	drug_central	Binding constant for ZAK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q8NE63	RO:0002436	drug_central	Binding constant for HIPK4 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q13163	RO:0002436	drug_central	Binding constant for MEK5 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O14733	RO:0002436	drug_central	Binding constant for MKK7 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O95819	RO:0002436	drug_central	Binding constant for MAP4K4 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P06241	RO:0002436	drug_central	Binding constant for FYN kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q05397	RO:0002436	drug_central	Binding constant for FAK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q14289	RO:0002436	drug_central	Binding constant for PYK2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P57059	RO:0002436	drug_central	Binding constant for SIK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P0C1S8	RO:0002436	drug_central	Binding constant for WEE2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q6XUX3	RO:0002436	drug_central	Binding constant for RIPK5 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q12866	RO:0002436	drug_central	Binding constant for MERTK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central	Binding constant for BTK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P06213	RO:0002436	drug_central	Binding constant for INSR kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central	Binding constant for JAK3(JH1domain-catalytic) kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central	Binding constant for MET kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q02763	RO:0002436	drug_central	Binding constant for TIE2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O96017	RO:0002436	drug_central	Binding constant for CHEK2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central	Binding constant for TNK2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9P2K8	RO:0002436	drug_central	Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q8N4C8	RO:0002436	drug_central	Binding constant for MINK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q92918	RO:0002436	drug_central	Binding constant for HPK1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O14757	RO:0002436	drug_central	Binding constant for CHEK1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P78368	RO:0002436	drug_central	Binding constant for CSNK1G2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P51617	RO:0002436	drug_central	Binding constant for IRAK1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P30530	RO:0002436	drug_central	Binding constant for AXL kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P51451	RO:0002436	drug_central	Binding constant for BLK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P50613	RO:0002436	drug_central	Binding constant for CDK7 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P49674	RO:0002436	drug_central	Binding constant for CSNK1E kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P21860	RO:0002436	drug_central	Binding constant for ERBB3 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P07332	RO:0002436	drug_central	Binding constant for FES kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P08631	RO:0002436	drug_central	Binding constant for HCK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central	Binding constant for LYN kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q99759	RO:0002436	drug_central	Binding constant for MAP3K3 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q16584	RO:0002436	drug_central	Binding constant for MLK3 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q02779	RO:0002436	drug_central	Binding constant for MLK2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q04912	RO:0002436	drug_central	Binding constant for MST1R kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P51955	RO:0002436	drug_central	Binding constant for NEK2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P51956	RO:0002436	drug_central	Binding constant for NEK3 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q13153	RO:0002436	drug_central	Binding constant for PAK1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q13177	RO:0002436	drug_central	Binding constant for PAK2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q15139	RO:0002436	drug_central	Binding constant for PRKD1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P45983	RO:0002436	drug_central	Binding constant for JNK1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P53779	RO:0002436	drug_central	Binding constant for JNK3 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central	Binding constant for MEK1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q15418	RO:0002436	drug_central	Binding constant for RSK1(Kin.Dom.1-N-terminal) kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P43405	RO:0002436	drug_central	Binding constant for SYK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central	Binding constant for TXK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P30291	RO:0002436	drug_central	Binding constant for WEE1 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9Y6E0	RO:0002436	drug_central	Binding constant for MST3 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q8IVH8	RO:0002436	drug_central	Binding constant for MAP4K3 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	Binding constant for FLT3(D835Y) kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O94768	RO:0002436	drug_central	Binding constant for DRAK2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:P41240	RO:0002436	drug_central	Binding constant for CSK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9Y6M4	RO:0002436	drug_central	Binding constant for CSNK1G3 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O15197	RO:0002436	drug_central	Binding constant for EPHB6 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q12851	RO:0002436	drug_central	Binding constant for MAP4K2 kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:O43283	RO:0002436	drug_central	Binding constant for LZK kinase domain	biolink:Association
DrugCentral:5252	biolink:molecularly_interacts_with	UniProtKB:Q9UEE5	RO:0002436	drug_central	Binding constant for DRAK1 kinase domain	biolink:Association
DrugCentral:5256	biolink:molecularly_interacts_with	UniProtKB:P42336	RO:0002436	drug_central		biolink:Association
DrugCentral:5256	biolink:molecularly_interacts_with	UniProtKB:O00329	RO:0002436	drug_central		biolink:Association
DrugCentral:5256	biolink:molecularly_interacts_with	UniProtKB:P42338	RO:0002436	drug_central		biolink:Association
DrugCentral:5256	biolink:molecularly_interacts_with	UniProtKB:P48736	RO:0002436	drug_central		biolink:Association
DrugCentral:5257	biolink:molecularly_interacts_with	UniProtKB:O95069	RO:0002436	drug_central		biolink:Association
DrugCentral:5258	biolink:molecularly_interacts_with	UniProtKB:P17948	RO:0002436	drug_central		biolink:Association
DrugCentral:5258	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central		biolink:Association
DrugCentral:5258	biolink:molecularly_interacts_with	UniProtKB:P35916	RO:0002436	drug_central		biolink:Association
DrugCentral:5258	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central		biolink:Association
DrugCentral:5258	biolink:molecularly_interacts_with	UniProtKB:P09619	RO:0002436	drug_central		biolink:Association
DrugCentral:5258	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central		biolink:Association
DrugCentral:5258	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central		biolink:Association
DrugCentral:5258	biolink:molecularly_interacts_with	UniProtKB:P08581	RO:0002436	drug_central		biolink:Association
DrugCentral:5259	biolink:molecularly_interacts_with	UniProtKB:P11802	RO:0002436	drug_central		biolink:Association
DrugCentral:5259	biolink:molecularly_interacts_with	UniProtKB:Q00534	RO:0002436	drug_central		biolink:Association
DrugCentral:5260	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central		biolink:Association
DrugCentral:5260	biolink:molecularly_interacts_with	UniProtKB:P51813	RO:0002436	drug_central		biolink:Association
DrugCentral:5260	biolink:molecularly_interacts_with	UniProtKB:P42680	RO:0002436	drug_central		biolink:Association
DrugCentral:5260	biolink:molecularly_interacts_with	UniProtKB:P42681	RO:0002436	drug_central		biolink:Association
DrugCentral:5260	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central		biolink:Association
DrugCentral:5260	biolink:molecularly_interacts_with	UniProtKB:P07948	RO:0002436	drug_central		biolink:Association
DrugCentral:5261	biolink:molecularly_interacts_with	UniProtKB:P43088	RO:0002436	drug_central	Value based on agonist activity of latanoprost.	biolink:Association
DrugCentral:5263	biolink:molecularly_interacts_with	UniProtKB:Q01344	RO:0002436	drug_central		biolink:Association
DrugCentral:5267	biolink:molecularly_interacts_with	UniProtKB:P43220	RO:0002436	drug_central		biolink:Association
DrugCentral:5269	biolink:molecularly_interacts_with	UniProtKB:O75116	RO:0002436	drug_central		biolink:Association
DrugCentral:5270	biolink:molecularly_interacts_with	UniProtKB:P31639	RO:0002436	drug_central		biolink:Association
DrugCentral:5270	biolink:molecularly_interacts_with	UniProtKB:P13866	RO:0002436	drug_central		biolink:Association
DrugCentral:5270	biolink:molecularly_interacts_with	UniProtKB:Q9NY91	RO:0002436	drug_central	Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of methyl alpha-D-glucopyranoside uptake after 1 hr	biolink:Association
DrugCentral:5271	biolink:molecularly_interacts_with	UniProtKB:Q92847	RO:0002436	drug_central	In a radioligand displacement assay using <sup>125</sup>I-labeled ghrelin as the probe, and human pituitary gland samples.	biolink:Association
DrugCentral:5272	biolink:molecularly_interacts_with	UniProtKB:P30556	RO:0002436	drug_central		biolink:Association
DrugCentral:5272	biolink:molecularly_interacts_with	UniProtKB:P50052	RO:0002436	drug_central		biolink:Association
DrugCentral:5275	biolink:molecularly_interacts_with	UniProtKB:P30874	RO:0002436	drug_central		biolink:Association
DrugCentral:5276	biolink:molecularly_interacts_with	UniProtKB:P13569	RO:0002436	drug_central		biolink:Association
DrugCentral:5277	biolink:molecularly_interacts_with	UniProtKB:Q12908	RO:0002436	drug_central		biolink:Association
DrugCentral:5278	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	equilibrium-binding affinity of ARN-509 for AR measured in competition with 16b-[18F]fluoro-5a-DHT	biolink:Association
DrugCentral:5279	biolink:molecularly_interacts_with	UniProtKB:P01730	RO:0002436	drug_central		biolink:Association
DrugCentral:5280	biolink:molecularly_interacts_with	UniProtKB:P43405	RO:0002436	drug_central		biolink:Association
DrugCentral:5280	biolink:molecularly_interacts_with	UniProtKB:P0DMS8	RO:0002436	drug_central		biolink:Association
DrugCentral:5281	biolink:molecularly_interacts_with	UniProtKB:P29460	RO:0002436	drug_central		biolink:Association
DrugCentral:5281	biolink:molecularly_interacts_with	UniProtKB:Q9NPF7	RO:0002436	drug_central		biolink:Association
DrugCentral:5282	biolink:molecularly_interacts_with	UniProtKB:Q9GZV9	RO:0002436	drug_central		biolink:Association
DrugCentral:5283	biolink:molecularly_interacts_with	UniProtKB:P25103	RO:0002436	drug_central	displacement of [3H]-labelled substance P from cloned human receptor expressed in CHO cells	biolink:Association
DrugCentral:5284	biolink:molecularly_interacts_with	UniProtKB:O60894	RO:0002436	drug_central		biolink:Association
DrugCentral:5284	biolink:molecularly_interacts_with	UniProtKB:Q16602	RO:0002436	drug_central		biolink:Association
DrugCentral:5285	biolink:molecularly_interacts_with	UniProtKB:P40238	RO:0002436	drug_central		biolink:Association
DrugCentral:5288	biolink:molecularly_interacts_with	UniProtKB:Q9Y2T6	RO:0002436	drug_central		biolink:Association
DrugCentral:5288	biolink:molecularly_interacts_with	UniProtKB:Q8NER1	RO:0002436	drug_central		biolink:Association
DrugCentral:5289	biolink:molecularly_interacts_with	UniProtKB:P15056	RO:0002436	drug_central		biolink:Association
DrugCentral:5289	biolink:molecularly_interacts_with	UniProtKB:P04049	RO:0002436	drug_central		biolink:Association
DrugCentral:5290	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central		biolink:Association
DrugCentral:5290	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central		biolink:Association
DrugCentral:5292	biolink:molecularly_interacts_with	UniProtKB:O75874	RO:0002436	drug_central	The enzyme and compound were preincubated for 1h	biolink:Association
DrugCentral:5293	biolink:molecularly_interacts_with	UniProtKB:P30968	RO:0002436	drug_central	determined by competition for [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from human GnRH receptor	biolink:Association
DrugCentral:5296	biolink:molecularly_interacts_with	UniProtKB:O00329	RO:0002436	drug_central	Enzymatic assay at 3mM ATP (nM)	biolink:Association
DrugCentral:5296	biolink:molecularly_interacts_with	UniProtKB:P48736	RO:0002436	drug_central	Enzymatic assay at 3mM ATP (nM)	biolink:Association
DrugCentral:5297	biolink:molecularly_interacts_with	UniProtKB:P00533	RO:0002436	drug_central	ELISA-Based erbB Kinase Assay with 20 uM [ATP]	biolink:Association
DrugCentral:5297	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	ELISA-Based erbB Kinase Assay with 20 uM [ATP]	biolink:Association
DrugCentral:5297	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central	ELISA-Based erbB Kinase Assay with 20 uM [ATP]	biolink:Association
DrugCentral:5300	biolink:molecularly_interacts_with	UniProtKB:P09874	RO:0002436	drug_central		biolink:Association
DrugCentral:5300	biolink:molecularly_interacts_with	UniProtKB:Q9UGN5	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:P08922	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:P29376	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:P16591	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:P07332	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:Q05397	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:Q14289	RO:0002436	drug_central		biolink:Association
DrugCentral:5302	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central		biolink:Association
DrugCentral:5303	biolink:molecularly_interacts_with	UniProtKB:P11229	RO:0002436	drug_central		biolink:Association
DrugCentral:5303	biolink:molecularly_interacts_with	UniProtKB:P08172	RO:0002436	drug_central		biolink:Association
DrugCentral:5303	biolink:molecularly_interacts_with	UniProtKB:P20309	RO:0002436	drug_central		biolink:Association
DrugCentral:5303	biolink:molecularly_interacts_with	UniProtKB:P08173	RO:0002436	drug_central		biolink:Association
DrugCentral:5303	biolink:molecularly_interacts_with	UniProtKB:P08912	RO:0002436	drug_central		biolink:Association
DrugCentral:5304	biolink:molecularly_interacts_with	UniProtKB:Q99835	RO:0002436	drug_central		biolink:Association
DrugCentral:5305	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central		biolink:Association
DrugCentral:5305	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central		biolink:Association
DrugCentral:5305	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central		biolink:Association
DrugCentral:5306	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central		biolink:Association
DrugCentral:5307	biolink:molecularly_interacts_with	UniProtKB:P41180	RO:0002436	drug_central		biolink:Association
DrugCentral:5308	biolink:molecularly_interacts_with	UniProtKB:P04275	RO:0002436	drug_central		biolink:Association
DrugCentral:5309	biolink:molecularly_interacts_with	UniProtKB:P03952	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5311	biolink:molecularly_interacts_with	UniProtKB:P13945	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5312	biolink:molecularly_interacts_with	UniProtKB:P43116	RO:0002436	drug_central	activity measured for the active metabolite (omidenepag)	biolink:Association
DrugCentral:5313	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5314	biolink:molecularly_interacts_with	UniProtKB:P20273	RO:0002436	drug_central		biolink:Association
DrugCentral:5315	biolink:molecularly_interacts_with	UniProtKB:P06881	RO:0002436	drug_central		biolink:Association
DrugCentral:5316	biolink:molecularly_interacts_with	UniProtKB:P06881	RO:0002436	drug_central		biolink:Association
DrugCentral:5317	biolink:molecularly_interacts_with	UniProtKB:Q15116	RO:0002436	drug_central		biolink:Association
DrugCentral:5319	biolink:molecularly_interacts_with	UniProtKB:P02766	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5320	biolink:molecularly_interacts_with	UniProtKB:P01579	RO:0002436	drug_central		biolink:Association
DrugCentral:5322	biolink:molecularly_interacts_with	UniProtKB:P01031	RO:0002436	drug_central		biolink:Association
DrugCentral:5323	biolink:molecularly_interacts_with	UniProtKB:P26951	RO:0002436	drug_central		biolink:Association
DrugCentral:5323	biolink:molecularly_interacts_with	UniProtKB:P32927	RO:0002436	drug_central		biolink:Association
DrugCentral:5324	biolink:molecularly_interacts_with	UniProtKB:P14867	RO:0002436	drug_central	Possible target. Activity determined against recombinant Ltk cells	biolink:Association
DrugCentral:5324	biolink:molecularly_interacts_with	UniProtKB:P18507	RO:0002436	drug_central	Possible target. Activity determined against recombinant Ltk cells	biolink:Association
DrugCentral:5324	biolink:molecularly_interacts_with	UniProtKB:P47870	RO:0002436	drug_central	Possible target. Activity determined against recombinant Ltk cells	biolink:Association
DrugCentral:5324	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Possible target. Activity determined against recombinant CHO cells	biolink:Association
DrugCentral:5324	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Possible target. Activity determined against recombinant CHO cells	biolink:Association
DrugCentral:5324	biolink:molecularly_interacts_with	UniProtKB:P48169	RO:0002436	drug_central	Possible target. Activity determined against recombinant CHO cells	biolink:Association
DrugCentral:5324	biolink:molecularly_interacts_with	UniProtKB:O14764	RO:0002436	drug_central	Possible target. Activity determined against recombinant CHO cells	biolink:Association
DrugCentral:5324	biolink:molecularly_interacts_with	UniProtKB:P28472	RO:0002436	drug_central	Possible target. Activity determined against recombinant CHO cells	biolink:Association
DrugCentral:5324	biolink:molecularly_interacts_with	UniProtKB:Q16445	RO:0002436	drug_central	Possible target. Activity determined against recombinant CHO cells	biolink:Association
DrugCentral:5325	biolink:molecularly_interacts_with	UniProtKB:Q01959	RO:0002436	drug_central	Binding affinity	biolink:Association
DrugCentral:5325	biolink:molecularly_interacts_with	UniProtKB:P23975	RO:0002436	drug_central	Binding affinity	biolink:Association
DrugCentral:5325	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central	Binding affinity	biolink:Association
DrugCentral:5326	biolink:molecularly_interacts_with	UniProtKB:P21453	RO:0002436	drug_central	Possible mechanism of action	biolink:Association
DrugCentral:5326	biolink:molecularly_interacts_with	UniProtKB:Q9H228	RO:0002436	drug_central	Possible mechanism of action	biolink:Association
DrugCentral:5326	biolink:molecularly_interacts_with	UniProtKB:O95136	RO:0002436	drug_central		biolink:Association
DrugCentral:5326	biolink:molecularly_interacts_with	UniProtKB:Q99500	RO:0002436	drug_central		biolink:Association
DrugCentral:5326	biolink:molecularly_interacts_with	UniProtKB:O95977	RO:0002436	drug_central		biolink:Association
DrugCentral:5327	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5327	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5327	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5327	biolink:molecularly_interacts_with	UniProtKB:P22455	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5327	biolink:molecularly_interacts_with	UniProtKB:P35968	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5328	biolink:molecularly_interacts_with	UniProtKB:P42336	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5329	biolink:molecularly_interacts_with	UniProtKB:Q01726	RO:0002436	drug_central		biolink:Association
DrugCentral:5329	biolink:molecularly_interacts_with	UniProtKB:P41968	RO:0002436	drug_central		biolink:Association
DrugCentral:5329	biolink:molecularly_interacts_with	UniProtKB:P33032	RO:0002436	drug_central		biolink:Association
DrugCentral:5329	biolink:molecularly_interacts_with	UniProtKB:Q01718	RO:0002436	drug_central		biolink:Association
DrugCentral:5329	biolink:molecularly_interacts_with	UniProtKB:P32245	RO:0002436	drug_central	Functional evaluation of PT‐141 at the MC4R was performed by measuring the accumulation of intracellular cAMP in HEK‐293 cells expressing MC4R	biolink:Association
DrugCentral:5330	biolink:molecularly_interacts_with	UniProtKB:O14980	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5331	biolink:molecularly_interacts_with	UniProtKB:P60880	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5333	biolink:molecularly_interacts_with	UniProtKB:P40259	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5333	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5333	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5333	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5333	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5333	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5333	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5333	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5333	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5333	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5334	biolink:molecularly_interacts_with	UniProtKB:P10275	RO:0002436	drug_central	Competitively inhibits androgen binding	biolink:Association
DrugCentral:5334	biolink:molecularly_interacts_with	UniProtKB:P06401	RO:0002436	drug_central		biolink:Association
DrugCentral:5335	biolink:molecularly_interacts_with	UniProtKB:P02656	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5337	biolink:molecularly_interacts_with	UniProtKB:Q9NPF7	RO:0002436	drug_central	selectively binds to the p19 subunit of human IL-23	biolink:Association
DrugCentral:5338	biolink:molecularly_interacts_with	UniProtKB:P17181	RO:0002436	drug_central	Patients showed a statistically significant difference in the JAK2V617F allele burden (19.7%) and JAK2V617F allele change from baseline (-22.9%)	biolink:Association
DrugCentral:5338	biolink:molecularly_interacts_with	UniProtKB:P48551	RO:0002436	drug_central	Patients showed a statistically significant difference in the JAK2V617F allele burden (19.7%) and JAK2V617F allele change from baseline (-22.9%)	biolink:Association
DrugCentral:5339	biolink:molecularly_interacts_with	UniProtKB:P13866	RO:0002436	drug_central		biolink:Association
DrugCentral:5339	biolink:molecularly_interacts_with	UniProtKB:P31639	RO:0002436	drug_central		biolink:Association
DrugCentral:5341	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central	FLT3 binding affinity in biochemical assay	biolink:Association
DrugCentral:5343	biolink:molecularly_interacts_with	UniProtKB:P07333	RO:0002436	drug_central		biolink:Association
DrugCentral:5343	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central		biolink:Association
DrugCentral:5343	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central		biolink:Association
DrugCentral:5345	biolink:molecularly_interacts_with	UniProtKB:P04629	RO:0002436	drug_central		biolink:Association
DrugCentral:5345	biolink:molecularly_interacts_with	UniProtKB:Q16620	RO:0002436	drug_central		biolink:Association
DrugCentral:5345	biolink:molecularly_interacts_with	UniProtKB:Q16288	RO:0002436	drug_central		biolink:Association
DrugCentral:5345	biolink:molecularly_interacts_with	UniProtKB:P08922	RO:0002436	drug_central		biolink:Association
DrugCentral:5345	biolink:molecularly_interacts_with	UniProtKB:Q9UM73	RO:0002436	drug_central		biolink:Association
DrugCentral:5345	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central		biolink:Association
DrugCentral:5345	biolink:molecularly_interacts_with	UniProtKB:Q07912	RO:0002436	drug_central		biolink:Association
DrugCentral:5346	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central		biolink:Association
DrugCentral:5346	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central		biolink:Association
DrugCentral:5346	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central		biolink:Association
DrugCentral:5347	biolink:molecularly_interacts_with	UniProtKB:O60674	RO:0002436	drug_central	wild type JAK2	biolink:Association
DrugCentral:5347	biolink:molecularly_interacts_with	UniProtKB:P36888	RO:0002436	drug_central		biolink:Association
DrugCentral:5347	biolink:molecularly_interacts_with	UniProtKB:P52333	RO:0002436	drug_central		biolink:Association
DrugCentral:5347	biolink:molecularly_interacts_with	UniProtKB:P23458	RO:0002436	drug_central		biolink:Association
DrugCentral:5347	biolink:molecularly_interacts_with	UniProtKB:P29597	RO:0002436	drug_central		biolink:Association
DrugCentral:5349	biolink:molecularly_interacts_with	UniProtKB:P48764	RO:0002436	drug_central	wild type	biolink:Association
DrugCentral:5350	biolink:molecularly_interacts_with	UniProtKB:P13631	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5350	biolink:molecularly_interacts_with	UniProtKB:P10276	RO:0002436	drug_central		biolink:Association
DrugCentral:5350	biolink:molecularly_interacts_with	UniProtKB:P10826	RO:0002436	drug_central		biolink:Association
DrugCentral:5351	biolink:molecularly_interacts_with	UniProtKB:P30939	RO:0002436	drug_central		biolink:Association
DrugCentral:5353	biolink:molecularly_interacts_with	UniProtKB:Q06187	RO:0002436	drug_central		biolink:Association
DrugCentral:5354	biolink:molecularly_interacts_with	UniProtKB:P13196	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5356	biolink:molecularly_interacts_with	UniProtKB:P69905	RO:0002436	drug_central	Hemoglobin S differs from hemoglobin A only by a single amino acid substitution: a valine replaces a glutamine in the 6th position of the beta chain of globin; forms a reversible covalent bond with the N‐terminal valine of the α chain of HbS.	biolink:Association
DrugCentral:5357	biolink:molecularly_interacts_with	UniProtKB:P11532	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5358	biolink:molecularly_interacts_with	UniProtKB:P28223	RO:0002436	drug_central		biolink:Association
DrugCentral:5358	biolink:molecularly_interacts_with	UniProtKB:P14416	RO:0002436	drug_central		biolink:Association
DrugCentral:5358	biolink:molecularly_interacts_with	UniProtKB:P31645	RO:0002436	drug_central		biolink:Association
DrugCentral:5358	biolink:molecularly_interacts_with	UniProtKB:P21728	RO:0002436	drug_central		biolink:Association
DrugCentral:5360	biolink:molecularly_interacts_with	UniProtKB:O43613	RO:0002436	drug_central		biolink:Association
DrugCentral:5360	biolink:molecularly_interacts_with	UniProtKB:O43614	RO:0002436	drug_central		biolink:Association
DrugCentral:5361	biolink:molecularly_interacts_with	UniProtKB:Q16602	RO:0002436	drug_central		biolink:Association
DrugCentral:5362	biolink:molecularly_interacts_with	UniProtKB:Q9BQB4	RO:0002436	drug_central		biolink:Association
DrugCentral:5363	biolink:molecularly_interacts_with	UniProtKB:P15692	RO:0002436	drug_central	binds to the three major isoforms of VEGF-A	biolink:Association
DrugCentral:5364	biolink:molecularly_interacts_with	UniProtKB:O95390	RO:0002436	drug_central		biolink:Association
DrugCentral:5364	biolink:molecularly_interacts_with	UniProtKB:O14793	RO:0002436	drug_central		biolink:Association
DrugCentral:5365	biolink:molecularly_interacts_with	UniProtKB:P16109	RO:0002436	drug_central	ex-vivo determination published in FDA's Multi-Discipline Review of BLA 761128	biolink:Association
DrugCentral:5366	biolink:molecularly_interacts_with	UniProtKB:Q96NY8	RO:0002436	drug_central		biolink:Association
DrugCentral:5366	biolink:molecularly_interacts_with	UniProtKB:P04350	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5366	biolink:molecularly_interacts_with	UniProtKB:P07437	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5366	biolink:molecularly_interacts_with	UniProtKB:P68371	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5366	biolink:molecularly_interacts_with	UniProtKB:Q13509	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5366	biolink:molecularly_interacts_with	UniProtKB:Q13885	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5366	biolink:molecularly_interacts_with	UniProtKB:Q3ZCM7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5366	biolink:molecularly_interacts_with	UniProtKB:Q9BUF5	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5366	biolink:molecularly_interacts_with	UniProtKB:Q9BVA1	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5366	biolink:molecularly_interacts_with	UniProtKB:Q9H4B7	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5367	biolink:molecularly_interacts_with	UniProtKB:P11387	RO:0002436	drug_central	cell-free DNA topoisomerase I inhibitory activity of DXd component	biolink:Association
DrugCentral:5367	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central	HER2-specific cell growth inhibition	biolink:Association
DrugCentral:5368	biolink:molecularly_interacts_with	UniProtKB:P60880	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5371	biolink:molecularly_interacts_with	UniProtKB:Q96KS0	RO:0002436	drug_central		biolink:Association
DrugCentral:5371	biolink:molecularly_interacts_with	UniProtKB:Q9GZT9	RO:0002436	drug_central		biolink:Association
DrugCentral:5371	biolink:molecularly_interacts_with	UniProtKB:Q9H6Z9	RO:0002436	drug_central		biolink:Association
DrugCentral:5372	biolink:molecularly_interacts_with	UniProtKB:P13569	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5375	biolink:molecularly_interacts_with	UniProtKB:P19838	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5375	biolink:molecularly_interacts_with	UniProtKB:Q13131	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5378	biolink:molecularly_interacts_with	UniProtKB:P09874	RO:0002436	drug_central	biotinylated [NAD+]-based luminescence assays	biolink:Association
DrugCentral:5378	biolink:molecularly_interacts_with	UniProtKB:Q9UGN5	RO:0002436	drug_central	biotinylated [NAD+]-based luminescence assays	biolink:Association
DrugCentral:5379	biolink:molecularly_interacts_with	UniProtKB:P16234	RO:0002436	drug_central	PDGFRA D842V (exon 18) mutant	biolink:Association
DrugCentral:5379	biolink:molecularly_interacts_with	UniProtKB:P10721	RO:0002436	drug_central	KIT D816V (exon 17)	biolink:Association
DrugCentral:5380	biolink:molecularly_interacts_with	UniProtKB:Q15910	RO:0002436	drug_central	Mechanism of Action	biolink:Association
DrugCentral:5380	biolink:molecularly_interacts_with	UniProtKB:Q92800	RO:0002436	drug_central		biolink:Association
DrugCentral:5381	biolink:molecularly_interacts_with	UniProtKB:Q16602	RO:0002436	drug_central		biolink:Association
DrugCentral:5382	biolink:molecularly_interacts_with	UniProtKB:P53396	RO:0002436	drug_central	Inhibition of ACL by ETC-1002-CoA	biolink:Association
DrugCentral:5383	biolink:molecularly_interacts_with	UniProtKB:P21453	RO:0002436	drug_central		biolink:Association
DrugCentral:5383	biolink:molecularly_interacts_with	UniProtKB:Q9H228	RO:0002436	drug_central		biolink:Association
DrugCentral:5384	biolink:molecularly_interacts_with	UniProtKB:P15538	RO:0002436	drug_central		biolink:Association
DrugCentral:5384	biolink:molecularly_interacts_with	UniProtKB:P19099	RO:0002436	drug_central		biolink:Association
DrugCentral:5385	biolink:molecularly_interacts_with	UniProtKB:P28907	RO:0002436	drug_central		biolink:Association
DrugCentral:5386	biolink:molecularly_interacts_with	UniProtKB:P06881	RO:0002436	drug_central		biolink:Association
DrugCentral:5386	biolink:molecularly_interacts_with	UniProtKB:P10092	RO:0002436	drug_central		biolink:Association
DrugCentral:5387	biolink:molecularly_interacts_with	UniProtKB:P08069	RO:0002436	drug_central		biolink:Association
DrugCentral:5388	biolink:molecularly_interacts_with	UniProtKB:Q02750	RO:0002436	drug_central		biolink:Association
DrugCentral:5388	biolink:molecularly_interacts_with	UniProtKB:P36507	RO:0002436	drug_central		biolink:Association
DrugCentral:5389	biolink:molecularly_interacts_with	UniProtKB:P04626	RO:0002436	drug_central		biolink:Association
DrugCentral:5389	biolink:molecularly_interacts_with	UniProtKB:P21860	RO:0002436	drug_central		biolink:Association
DrugCentral:5389	biolink:molecularly_interacts_with	UniProtKB:Q15303	RO:0002436	drug_central		biolink:Association
DrugCentral:5390	biolink:molecularly_interacts_with	UniProtKB:P11362	RO:0002436	drug_central		biolink:Association
DrugCentral:5390	biolink:molecularly_interacts_with	UniProtKB:P21802	RO:0002436	drug_central		biolink:Association
DrugCentral:5390	biolink:molecularly_interacts_with	UniProtKB:P22607	RO:0002436	drug_central		biolink:Association
DrugCentral:5390	biolink:molecularly_interacts_with	UniProtKB:P22455	RO:0002436	drug_central		biolink:Association